TreeWAS – Variant ID: rs1351394

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.866	0.134	0.000
E11 Non-insulin-dependent diabetes mellitus	0.766	0.234	0.000
E11.3 With ophthalmic complications	0.748	0.252	0.000
E11.8 With unspecified complications	0.669	0.331	0.000
E11.6 With other specified complications	0.667	0.333	0.000
E11.1 With ketoacidosis	0.605	0.395	0.000
E11.7 With multiple complications	0.549	0.451	0.000
E11.0 With coma	0.520	0.479	0.000
E11.2 With renal complications	0.422	0.578	0.000
E11.5 With peripheral circulatory complications	0.380	0.620	0.000
E11.4 With neurological complications	0.236	0.763	0.000
E10-E14 Diabetes mellitus	0.059	0.941	0.000
I89.0 Lymphoedema, not elsewhere classified	0.046	0.954	0.000
C43.5 Malignant melanoma of trunk	0.000	0.958	0.042
E12 Malnutrition-related diabetes mellitus	0.042	0.958	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.958	0.042
C43 Malignant melanoma of skin	0.000	0.959	0.041
C43.9 Malignant melanoma of skin, unspecified	0.000	0.962	0.038
C43.4 Malignant melanoma of scalp and neck	0.000	0.962	0.038
N36.8 Other specified disorders of urethra	0.000	0.963	0.037
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.036	0.964	0.000
N36.2 Urethral caruncle	0.000	0.966	0.034
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.967	0.033
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.033	0.967	0.000
N36 Other disorders of urethra	0.000	0.967	0.033
E13 Other specified diabetes mellitus	0.032	0.968	0.000
E12.9 Without complications	0.030	0.969	0.000
E12.8 With unspecified complications	0.030	0.969	0.000
E12.7 With multiple complications	0.030	0.969	0.000
E12.6 With other specified complications	0.030	0.969	0.000
E12.5 With peripheral circulatory complications	0.030	0.969	0.000
E12.4 With neurological complications	0.030	0.969	0.000
E12.3 With ophthalmic complications	0.030	0.969	0.000
E12.2 With renal complications	0.030	0.969	0.000
E12.1 With ketoacidosis	0.030	0.969	0.000
E12.0 With coma	0.030	0.969	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.970	0.030
C43.0 Malignant melanoma of lip	0.000	0.970	0.030
I89.1 Lymphangitis	0.029	0.971	0.000
E04.2 Non-toxic multinodular goitre	0.028	0.972	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.027	0.973	0.000
N36.1 Urethral diverticulum	0.000	0.973	0.027
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.973	0.027
N36.3 Prolapsed urethral mucosa	0.000	0.976	0.024
E13.3 With ophthalmic complications	0.023	0.976	0.000
E13.8 With unspecified complications	0.023	0.977	0.000
E13.7 With multiple complications	0.023	0.977	0.000
E13.6 With other specified complications	0.023	0.977	0.000
E13.5 With peripheral circulatory complications	0.023	0.977	0.000
E13.4 With neurological complications	0.023	0.977	0.000
E13.2 With renal complications	0.023	0.977	0.000
E13.1 With ketoacidosis	0.023	0.977	0.000
E13.0 With coma	0.023	0.977	0.000
E14 Unspecified diabetes mellitus	0.023	0.977	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.977	0.023
N36.9 Urethral disorder, unspecified	0.000	0.977	0.022
E14.2 Withrenal complications	0.020	0.980	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.980	0.020
M06.9 Rheumatoid arthritis, unspecified	0.000	0.982	0.018
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.983	0.017
E14.1 With ketoacidosis	0.017	0.983	0.000
N36.0 Urethral fistula	0.000	0.983	0.017
E14.7 With multiple complications	0.016	0.983	0.000
E14.0 With coma	0.016	0.983	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.984	0.016
E14.8 With unspecified complications	0.016	0.984	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.984	0.016
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.984	0.016
E14.4 With neurological complications	0.016	0.984	0.000
E14.9 Without complications	0.015	0.985	0.000
E14.6 With other specified complications	0.014	0.985	0.000
M06 Other rheumatoid arthritis	0.000	0.985	0.015
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.986	0.014
I77.8 Other specified disorders of arteries and arterioles	0.014	0.986	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.986	0.014
D75.2 Essential thrombocytosis	0.014	0.986	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.987	0.013
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.987	0.013
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.988	0.012
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.988	0.012
E13.9 Without complications	0.012	0.988	0.000
E14.5 With peripheral circulatory complications	0.012	0.988	0.000
I77 Other disorders of arteries and arterioles	0.011	0.989	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.989	0.011
M06.3 Rheumatoid nodule	0.000	0.989	0.011
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.989	0.011
I77.6 Arteritis, unspecified	0.011	0.989	0.000
M06.2 Rheumatoid bursitis	0.000	0.989	0.011
M06.1 Adult-onset Still's disease	0.000	0.989	0.011
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.989	0.010
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.989	0.011
E10 Insulin-dependent diabetes mellitus	0.010	0.990	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.990	0.010
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.990	0.010
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.990	0.010
M06.34 Rheumatoid nodule (Hand)	0.000	0.990	0.010
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.990	0.010
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.990	0.010
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.990	0.010
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.990	0.010
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.990	0.010
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.990	0.010
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.990	0.010
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.990	0.010
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.990	0.010
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.990	0.010
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.990	0.010
E04 Other non-toxic goitre	0.010	0.990	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.990	0.010
I77.0 Arteriovenous fistula, acquired	0.010	0.990	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.990	0.009
I77.3 Arterial fibromuscular dysplasia	0.009	0.991	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.991	0.009
E61.1 Iron deficiency	0.009	0.991	0.000
D86.9 Sarcoidosis, unspecified	0.009	0.991	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.991	0.009
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.991	0.008
E10.6 With other specified complications	0.008	0.991	0.000
E10.0 With coma	0.008	0.991	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.008	0.992	0.000
E10.1 With ketoacidosis	0.008	0.992	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.008	0.992	0.000
I77.5 Necrosis of artery	0.008	0.992	0.000
I77.4 Coeliac artery compression syndrome	0.008	0.992	0.000
E61 Deficiency of other nutrient elements	0.008	0.992	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.992	0.008
M06.38 Rheumatoid nodule (Other)	0.000	0.992	0.008
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.992	0.008
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.992	0.008
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.992	0.008
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
I77.2 Rupture of artery	0.008	0.992	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.992	0.008
M06.18 Adult-onset Still's disease (Other)	0.000	0.992	0.008
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.992	0.008
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.992	0.008
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.992	0.008
M06.14 Adult-onset Still's disease (Hand)	0.000	0.992	0.008
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.992	0.008
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.992	0.008
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.992	0.008
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.992	0.008
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.992	0.008
M06.28 Rheumatoid bursitis (Other)	0.000	0.992	0.008
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.992	0.008
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.992	0.008
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.992	0.008
M06.24 Rheumatoid bursitis (Hand)	0.000	0.992	0.008
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.992	0.008
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.992	0.008
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.992	0.008
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.992	0.008
E14.3 With ophthalmic complications	0.008	0.992	0.000
E04.0 Non-toxic diffuse goitre	0.008	0.992	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.992	0.008
D86 Sarcoidosis	0.008	0.992	0.000
M06.33 Rheumatoid nodule (Forearm)	0.000	0.992	0.007
E10.7 With multiple complications	0.007	0.993	0.000
E04.8 Other specified non-toxic goitre	0.007	0.993	0.000
D80-D89 Certain disorders involving the immune mechanism	0.007	0.993	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.993	0.007
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.993	0.007
E10.8 With unspecified complications	0.007	0.993	0.000
D84 Other immunodeficiencies	0.007	0.993	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.993	0.007
E58 Dietary calcium deficiency	0.007	0.993	0.000
I77.1 Stricture of artery	0.007	0.993	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.993	0.007
E00-E07 Disorders of thyroid gland	0.007	0.993	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.993	0.006
D80 Immunodeficiency with predominantly antibody defects	0.007	0.993	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.993	0.006
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.993	0.006
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.993	0.006
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.993	0.006
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.993	0.006
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.993	0.006
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.993	0.006
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.993	0.006
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.993	0.007
E40-E46 Malnutrition	0.007	0.993	0.000
D86.0 Sarcoidosis of lung	0.007	0.993	0.000
E56 Other vitamin deficiencies	0.006	0.993	0.000
D84.9 Immunodeficiency, unspecified	0.006	0.993	0.000
E10.3 With ophthalmic complications	0.006	0.994	0.000
E10.2 With renal complications	0.006	0.994	0.000
E51 Thiamine deficiency	0.006	0.994	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.006	0.994	0.000
E61.9 Deficiency of nutrient element, unspecified	0.006	0.994	0.000
E61.8 Deficiency of other specified nutrient elements	0.006	0.994	0.000
E61.7 Deficiency of multiple nutrient elements	0.006	0.994	0.000
E61.6 Vanadium deficiency	0.006	0.994	0.000
E61.5 Molybdenum deficiency	0.006	0.994	0.000
E61.4 Chromium deficiency	0.006	0.994	0.000
E61.3 Manganese deficiency	0.006	0.994	0.000
E61.0 Copper deficiency	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.006	0.994	0.000
D47.2 Monoclonal gammopathy	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.006	0.994	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.006	0.994	0.000
D84.8 Other specified immunodeficiencies	0.006	0.994	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.994	0.005
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.994	0.005
D86.8 Sarcoidosis of other and combined sites	0.006	0.994	0.000
D83 Common variable immunodeficiency	0.006	0.994	0.000
T51.9 Alcohol, unspecified	0.006	0.994	0.000
E61.2 Magnesium deficiency	0.005	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.005	0.994	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.994	0.000
D82 Immunodeficiency associated with other major defects	0.005	0.994	0.000
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.995	0.005
D81 Combined immunodeficiencies	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.005	0.995	0.000
E56.1 Deficiency of vitamin K	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D84.1 Defects in the complement system	0.005	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.005	0.995	0.000
E46 Unspecified protein-energy malnutrition	0.005	0.995	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.995	0.005
I62.1 Nontraumatic extradural haemorrhage	0.000	0.995	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.995	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E00 Congenital iodine-deficiency syndrome	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.005	0.995	0.000
E45 Retarded development following protein-energy malnutrition	0.005	0.995	0.000
E43 Unspecified severe protein-energy malnutrition	0.005	0.995	0.000
E42 Marasmic kwashiorkor	0.005	0.995	0.000
E41 Nutritional marasmus	0.005	0.995	0.000
E40 Kwashiorkor	0.005	0.995	0.000
E51.2 Wernicke's encephalopathy	0.005	0.995	0.000
E56.9 Vitamin deficiency, unspecified	0.005	0.995	0.000
E56.8 Deficiency of other vitamins	0.005	0.995	0.000
E56.0 Deficiency of vitamin E	0.005	0.995	0.000
I65.2 Occlusion and stenosis of carotid artery	0.005	0.995	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.005	0.995	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
M79.69 Pain in limb (Site unspecified)	0.000	0.995	0.005
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.005	0.995	0.000
D83.9 Common variable immunodeficiency, unspecified	0.005	0.995	0.000
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
W18.3 Sports and athletics area	0.005	0.995	0.000
E04.9 Non-toxic goitre, unspecified	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.005	0.995	0.000
E51.8 Other manifestations of thiamine deficiency	0.005	0.995	0.000
E51.1 Beriberi	0.005	0.995	0.000
D86.3 Sarcoidosis of skin	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
J86.9 Pyothorax without fistula	0.005	0.995	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.995	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.995	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.995	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.995	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.995	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.995	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.995	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.995	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.995	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.004	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.004	0.995	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.995	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.995	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.995	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.995	0.000
E64.3 Sequelae of rickets	0.004	0.995	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.995	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.995	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.995	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.005	0.995	0.000
R82.9 Other and unspecified abnormal finding in urine	0.005	0.995	0.000
E06 Thyroiditis	0.005	0.995	0.000
E55 Vitamin D deficiency	0.004	0.995	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.004	0.995	0.000
O30.0 Twin pregnancy	0.000	0.996	0.004
D83.8 Other common variable immunodeficiencies	0.004	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.004	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.004	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.004	0.996	0.000
K50.8 Other Crohn's disease	0.000	0.996	0.004
D82.1 Di George's syndrome	0.004	0.996	0.000
R82.4 Acetonuria	0.004	0.996	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.004	0.996	0.000
D47.4 Osteomyelofibrosis	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.004	0.996	0.000
E53.0 Riboflavin deficiency	0.004	0.996	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.004	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.004	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.004	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.004	0.996	0.000
O41.0 Oligohydramnios	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.004	0.996	0.000
D81.8 Other combined immunodeficiencies	0.004	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.004	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.004	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.004	0.996	0.000
D81.4 Nezelof's syndrome	0.004	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.004	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.004	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.004	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.004	0.996	0.000
E20 Hypoparathyroidism	0.004	0.996	0.000
R82 Other abnormal findings in urine	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
E10.4 With neurological complications	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.996	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.004	0.996	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.004	0.996	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.004	0.996	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.004	0.996	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.004	0.996	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.004	0.996	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.004	0.996	0.000
L03.2 Cellulitis of face	0.004	0.996	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.996	0.004
E44.1 Mild protein-energy malnutrition	0.004	0.996	0.000
E44.0 Moderate protein-energy malnutrition	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.004	0.996	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.996	0.004
E06.1 Subacute thyroiditis	0.003	0.996	0.000
I47.2 Ventricular tachycardia	0.000	0.996	0.004
M31.6 Other giant cell arteritis	0.004	0.996	0.000
E15 Nondiabetic hypoglycaemic coma	0.003	0.996	0.000
E06.5 Other chronic thyroiditis	0.003	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.004	0.996	0.000
E25 Adrenogenital disorders	0.003	0.996	0.000
E06.4 Drug-induced thyroiditis	0.003	0.996	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.003	0.996	0.000
E06.0 Acute thyroiditis	0.003	0.996	0.000
E31 Polyglandular dysfunction	0.003	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.996	0.000
E34.0 Carcinoid syndrome	0.003	0.996	0.000
E55.0 Rickets, active	0.003	0.996	0.000
E65-E68 Obesity and other hyperalimentation	0.003	0.996	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
K80.4 Calculus of bile duct with cholecystitis	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
M31.3 Wegener's granulomatosis	0.003	0.997	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.997	0.003
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R82.3 Haemoglobinuria	0.003	0.997	0.000
R82.2 Biliuria	0.003	0.997	0.000
R82.0 Chyluria	0.003	0.997	0.000
R82.1 Myoglobinuria	0.003	0.997	0.000
E07 Other disorders of thyroid	0.003	0.997	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.997	0.003
K22.8 Other specified diseases of oesophagus	0.003	0.997	0.000
E10.9 Without complications	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.997	0.003
E28 Ovarian dysfunction	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
W18.1 Residential institution	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.997	0.003
W18 Other fall on same level	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.003	0.997	0.000
M31 Other necrotising vasculopathies	0.003	0.997	0.000
D75 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
E67 Other hyperalimentation	0.003	0.997	0.000
E68 Sequelae of hyperalimentation	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
M31.7 Microscopic polyangiitis	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.997	0.000
M31.8 Other specified necrotising vasculopathies	0.003	0.997	0.000
E07.1 Dyshormogenetic goitre	0.002	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.003	0.997	0.000
H55-H59 Other disorders of eye and adnexa	0.000	0.997	0.003
K27 Peptic ulcer, site unspecified	0.003	0.997	0.000
K27.7 Chronic without haemorrhage or perforation	0.002	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
M31.9 Necrotising vasculopathy, unspecified	0.002	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.997	0.000
E28.8 Other ovarian dysfunction	0.002	0.997	0.000
E28.1 Androgen excess	0.002	0.997	0.000
E28.0 Oestrogen excess	0.002	0.997	0.000
J86 Pyothorax	0.002	0.997	0.000
I49.3 Ventricular premature depolarisation	0.000	0.997	0.002
I65.1 Occlusion and stenosis of basilar artery	0.002	0.997	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.997	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
W18.9 Unspecified place	0.002	0.998	0.000
W18.8 Other specified place	0.002	0.998	0.000
W18.4 Street and highway	0.002	0.998	0.000
W18.2 School, other institution and public administrative area	0.002	0.998	0.000
W18.0 Home	0.002	0.998	0.000
W18.7 Farm	0.002	0.998	0.000
W18.6 Industrial and construction area	0.002	0.998	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
W18.5 Trade and service area	0.002	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
E65 Localised adiposity	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.002	0.998	0.000
E67.3 Hypervitaminosis D	0.002	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.002	0.998	0.000
E67.1 Hypercarotenaemia	0.002	0.998	0.000
E67.0 Hypervitaminosis A	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
J32.9 Chronic sinusitis, unspecified	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations