TreeWAS – Variant ID: rs1351696

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I10-I15 Hypertensive diseases	0.816	0.184	0.000
I12 Hypertensive renal disease	0.766	0.234	0.000
I12.0 Hypertensive renal disease with renal failure	0.731	0.269	0.000
I11 Hypertensive heart disease	0.676	0.323	0.000
I13 Hypertensive heart and renal disease	0.590	0.409	0.000
I12.9 Hypertensive renal disease without renal failure	0.551	0.449	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.550	0.450	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.525	0.475	0.000
I15 Secondary hypertension	0.518	0.482	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.454	0.545	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.423	0.576	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.421	0.579	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.395	0.605	0.000
I15.2 Hypertension secondary to endocrine disorders	0.374	0.626	0.000
I15.9 Seconday hypertension, unspecified	0.360	0.640	0.000
I15.8 Other secondary hypertension	0.358	0.641	0.000
I15.1 Hypertension secondary to other renal disorders	0.355	0.645	0.000
I15.0 Renovascular hypertension	0.353	0.647	0.000
L57.0 Actinic keratosis	0.085	0.915	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.062	0.938	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.048	0.952	0.000
L57.5 Actinic granuloma	0.046	0.953	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.045	0.955	0.000
L57.3 Poikiloderma of Civatte	0.044	0.955	0.000
L57.2 Cutis rhomboidalis nuchae	0.044	0.955	0.000
L57.1 Actinic reticuloid	0.044	0.955	0.000
L57.4 Cutis laxa senilis	0.044	0.956	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.042	0.958	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.038	0.962	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.036	0.963	0.000
L58 Radiodermatitis	0.034	0.966	0.000
L55 Sunburn	0.033	0.967	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.033	0.967	0.000
L56.4 Polymorphous light eruption	0.033	0.967	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.032	0.967	0.000
L56.3 Solar urticaria	0.030	0.970	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.030	0.970	0.000
L56.1 Drug photoallergic response	0.030	0.970	0.000
L56.0 Drug phototoxic response	0.030	0.970	0.000
L58.9 Radiodermatitis, unspecified	0.025	0.974	0.000
L55.9 Sunburn, unspecified	0.025	0.975	0.000
L58.1 Chronic radiodermatitis	0.024	0.975	0.000
L58.0 Acute radiodermatitis	0.024	0.975	0.000
L55.8 Other sunburn	0.024	0.976	0.000
L55.2 Sunburn of third degree	0.024	0.976	0.000
L55.1 Sunburn of second degree	0.024	0.976	0.000
L55.0 Sunburn of first degree	0.024	0.976	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.024	0.976	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.023	0.976	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.023	0.977	0.000
I50.1 Left ventricular failure	0.020	0.980	0.000
I50.0 Congestive heart failure	0.016	0.984	0.000
I50 Heart failure	0.015	0.985	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.986	0.014
G35 Multiple sclerosis	0.000	0.986	0.014
S42.30 Fracture of shaft of humerus (closed)	0.000	0.992	0.008
R20.2 Paraesthesia of skin	0.007	0.993	0.000
L03.3 Cellulitis of trunk	0.007	0.993	0.000
E23.0 Hypopituitarism	0.007	0.993	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.993	0.007
I50.9 Heart failure, unspecified	0.007	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
H40.9 Glaucoma, unspecified	0.000	0.994	0.006
E27.4 Other and unspecified adrenocortical insufficiency	0.006	0.994	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.006	0.994	0.000
K63.8 Other specified diseases of intestine	0.006	0.994	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.006	0.994	0.000
E21.0 Primary hyperparathyroidism	0.006	0.994	0.000
D86 Sarcoidosis	0.006	0.994	0.000
E23.2 Diabetes insipidus	0.006	0.994	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.006	0.994	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.994	0.006
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.995	0.005
D86.0 Sarcoidosis of lung	0.005	0.995	0.000
E80.4 Gilbert's syndrome	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.005	0.995	0.000
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.005	0.995	0.000
D86.3 Sarcoidosis of skin	0.005	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
S42.3 Fracture of shaft of humerus	0.000	0.996	0.004
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.996	0.000
L40.9 Psoriasis, unspecified	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.996	0.004
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
Z83.7 Family history of diseases of the digestive system	0.004	0.996	0.000
G62.8 Other specified polyneuropathies	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
I67.9 Cerebrovascular disease, unspecified	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
G36 Other acute disseminated demyelination	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.004	0.996	0.000
E27.0 Other adrenocortical overactivity	0.004	0.996	0.000
E25 Adrenogenital disorders	0.004	0.996	0.000
J81 Pulmonary oedema	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.996	0.004
D48.1 Connective and other soft tissue	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
G62 Other polyneuropathies	0.004	0.996	0.000
E28 Ovarian dysfunction	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.003	0.996	0.000
E20 Hypoparathyroidism	0.003	0.996	0.000
E26 Hyperaldosteronism	0.003	0.996	0.000
K63.1 Perforation of intestine (nontraumatic)	0.004	0.996	0.000
G62.0 Drug-induced polyneuropathy	0.003	0.997	0.000
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.997	0.003
Z86.0 Personal history of other neoplasms	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.997	0.003
G37.4 Subacute necrotising myelitis	0.000	0.997	0.003
G37.2 Central pontine myelinolysis	0.000	0.997	0.003
G37.1 Central demyelination of corpus callosum	0.000	0.997	0.003
G37.0 Diffuse sclerosis	0.000	0.997	0.003
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.997	0.003
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
J84 Other interstitial pulmonary diseases	0.003	0.997	0.000
K63 Other diseases of intestine	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.000	0.997	0.003
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.997	0.003
K63.2 Fistula of intestine	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
M94.88 Other specified disorders of cartilage (Other)	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.997	0.003
G36.8 Other specified acute disseminated demyelination	0.000	0.997	0.003
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.997	0.003
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.003	0.997	0.000
L40 Psoriasis	0.003	0.997	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
K63.0 Abscess of intestine	0.003	0.997	0.000
L40.0 Psoriasis vulgaris	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
N90.7 Vulvar cyst	0.003	0.997	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.003	0.997	0.000
G62.2 Polyneuropathy due to other toxic agents	0.003	0.997	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
N36.2 Urethral caruncle	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
M94.8 Other specified disorders of cartilage	0.003	0.997	0.000
N36.3 Prolapsed urethral mucosa	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.997	0.000
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.997	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.997	0.003
J82 Pulmonary eosinophilia, not elsewhere classified	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
N36.9 Urethral disorder, unspecified	0.003	0.997	0.000
N36 Other disorders of urethra	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
E80.6 Other disorders of bilirubin metabolism	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.002	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.997	0.000
E22.1 Hyperprolactinaemia	0.002	0.997	0.000
N93.0 Postcoital and contact bleeding	0.003	0.997	0.000
E34 Other endocrine disorders	0.002	0.997	0.000
K63.4 Enteroptosis	0.002	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.997	0.000
E80.1 Porphyria cutanea tarda	0.002	0.997	0.000
J84.0 Alveolar and parietoalveolar conditions	0.002	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.997	0.000
L40.4 Guttate psoriasis	0.002	0.998	0.000
L40.2 Acrodermatitis continua	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
Z83.3 Family history of diabetes mellitus	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.000	0.998	0.002
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
N36.1 Urethral diverticulum	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.002
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
L40.1 Generalised pustular psoriasis	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
L40.8 Other psoriasis	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.000	0.998	0.002
L40.3 Pustulosis palmaris et plantaris	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
H49 Paralytic strabismus	0.000	0.998	0.002
Chapter XII Diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
L40-L45 Papulosquamous disorders	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.002	0.998	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Z83 Family history of other specific disorders	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
F41.1 Generalised anxiety disorder	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
K63.3 Ulcer of intestine	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
N36.0 Urethral fistula	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.000	0.998	0.002
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
L40.5 Arthropathic psoriasis	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.998	0.002
M24.18 Other articular cartilage disorders (Other)	0.000	0.998	0.002
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.998	0.002
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.000	0.998	0.002
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
L44 Other papulosquamous disorders	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
L41 Parapsoriasis	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.000	0.998	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.001	0.998	0.000
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.998	0.002
Z83.0 Family history of human immunodeficiency virus [HIV]	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.002	0.998	0.000
L71.1 Rhinophyma	0.002	0.998	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.998	0.002
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
Z91.5 Personal history of self-harm	0.002	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
L82 Seborrhoeic keratosis	0.000	0.998	0.002
G81.9 Hemiplegia, unspecified	0.002	0.998	0.000
Z83.6 Family history of diseases of the respiratory system	0.002	0.998	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.002	0.998	0.000
Z87.8 Personal history of other specified conditions	0.002	0.998	0.000
L20-L30 Dermatitis and eczema	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.998	0.001
L44.0 Pityriasis rubra pilaris	0.001	0.998	0.000
Z90.0 Acquired absence of part of head and neck	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
L41.1 Pityriasis lichenoides chronica	0.001	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
L41.9 Parapsoriasis, unspecified	0.001	0.998	0.000
L41.8 Other parapsoriasis	0.001	0.998	0.000
L41.5 Retiform parapsoriasis	0.001	0.998	0.000
L41.4 Large plaque parapsoriasis	0.001	0.998	0.000
L41.3 Small plaque parapsoriasis	0.001	0.998	0.000
L41.2 Lymphomatoid papulosis	0.001	0.998	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.001	0.998	0.000
L44.9 Papulosquamous disorder, unspecified	0.001	0.998	0.000
L44.8 Other specified papulosquamous disorders	0.001	0.998	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.001	0.998	0.000
L44.3 Lichen ruber moniliformis	0.001	0.998	0.000
L44.2 Lichen striatus	0.001	0.998	0.000
L44.1 Lichen nitidus	0.001	0.998	0.000
L29 Pruritus	0.002	0.998	0.000
L42 Pityriasis rosea	0.001	0.998	0.000
L29.0 Pruritus ani	0.002	0.998	0.000
Y40.6 Rifamycins	0.001	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.002	0.998	0.000
R82.1 Myoglobinuria	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
L10-L14 Bullous disorders	0.001	0.998	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.998	0.000
L29.8 Other pruritus	0.002	0.998	0.000
M94.2 Chondromalacia	0.001	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
L30 Other dermatitis	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
G64 Other disorders of peripheral nervous system	0.001	0.998	0.000
R82 Other abnormal findings in urine	0.002	0.998	0.000
L30.3 Infective dermatitis	0.001	0.998	0.000
S80.0 Contusion of knee	0.001	0.998	0.000
Y40.5 Aminoglycosides	0.001	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
H02.3 Blepharochalasis	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.001
H52.0 Hypermetropia	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.001	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.001	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.001	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
L25 Unspecified contact dermatitis	0.001	0.998	0.000
L24 Irritant contact dermatitis	0.001	0.998	0.000
L22 Diaper [napkin] dermatitis	0.001	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.998	0.000
G61.0 Guillain-Barre syndrome	0.001	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.001
L30.0 Nummular dermatitis	0.001	0.998	0.000
Y40.8 Other systemic antibiotics	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
G61.1 Serum neuropathy	0.001	0.998	0.000
K11.5 Sialolithiasis	0.000	0.998	0.001
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
L23 Allergic contact dermatitis	0.001	0.998	0.000
L20 Atopic dermatitis	0.001	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.001	0.999	0.000
M94.3 Chondrolysis	0.001	0.999	0.000
M94.1 Relapsing polychondritis	0.001	0.999	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
R82.4 Acetonuria	0.001	0.999	0.000
Y52.1 Calcium-channel blockers	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
L27 Dermatitis due to substances taken internally	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
K63.9 Disease of intestine, unspecified	0.001	0.999	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.001	0.999	0.000
L29.9 Pruritus, unspecified	0.001	0.999	0.000
L29.1 Pruritus scroti	0.001	0.999	0.000
L30.4 Erythema intertrigo	0.001	0.999	0.000
N76.2 Acute vulvitis	0.001	0.999	0.000
N76.0 Acute vaginitis	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
L26 Exfoliative dermatitis	0.001	0.999	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
G60.3 Idiopathic progressive neuropathy	0.001	0.999	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.001	0.999	0.000
G60.1 Refsum's disease	0.001	0.999	0.000
G60.0 Hereditary motor and sensory neuropathy	0.001	0.999	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.999	0.000
N90.6 Hypertrophy of vulva	0.001	0.999	0.000
O36.8 Maternal care for other specified foetal problems	0.001	0.999	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.999	0.000
Y41.5 Antiviral drugs	0.001	0.999	0.000
Y41.4 Anthelminthics	0.001	0.999	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.999	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.999	0.000
R20 Disturbances of skin sensation	0.001	0.999	0.000
N76.1 Subacute and chronic vaginitis	0.001	0.999	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
Z31.2 In vitro fertilisation	0.000	0.999	0.001
L71 Rosacea	0.001	0.999	0.000
M94.29 Chondromalacia (Site unspecified)	0.001	0.999	0.000
M94.28 Chondromalacia (Other)	0.001	0.999	0.000
M94.27 Chondromalacia (Ankle and foot)	0.001	0.999	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.001	0.999	0.000
M94.24 Chondromalacia (Hand)	0.001	0.999	0.000
M94.23 Chondromalacia (Forearm)	0.001	0.999	0.000
M94.22 Chondromalacia (Upper arm)	0.001	0.999	0.000
M94.21 Chondromalacia (Shoulder region)	0.001	0.999	0.000
M94.20 Chondromalacia (Multiple sites)	0.001	0.999	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.999	0.001
L30.8 Other specified dermatitis	0.001	0.999	0.000
L30.5 Pityriasis alba	0.001	0.999	0.000
L30.2 Cutaneous autosensitisation	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
L12 Pemphigoid	0.001	0.999	0.000
L14 Bullous disorders in diseases classified elsewhere	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.001	0.999	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.999	0.001
L30.1 Dyshidrosis [pompholyx]	0.001	0.999	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R82.3 Haemoglobinuria	0.001	0.999	0.000
R82.2 Biliuria	0.001	0.999	0.000
R82.0 Chyluria	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
I83 Varicose veins of lower extremities	0.000	0.999	0.001
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.001	0.999	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.001	0.999	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.999	0.001
G63.8 Polyneuropathy in other diseases classified elsewhere	0.001	0.999	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.001	0.999	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.001	0.999	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.001	0.999	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.001	0.999	0.000
G63.1 Polyneuropathy in neoplastic disease	0.001	0.999	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations