TreeWAS – Variant ID: rs1353899

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z83.5 Family history of eye and ear disorders	0.000	0.967	0.033
G56.0 Carpal tunnel syndrome	0.000	0.981	0.019
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.982	0.018
N97.9 Female infertility, unspecified	0.017	0.983	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.990	0.010
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.991	0.009
D69 Purpura and other haemorrhagic conditions	0.000	0.991	0.009
K35.8 Acute appendicitis, other and unspecified	0.009	0.991	0.000
H61.2 Impacted cerumen	0.007	0.993	0.000
D69.0 Allergic purpura	0.000	0.993	0.007
D69.5 Secondary thrombocytopenia	0.000	0.993	0.007
D69.2 Other nonthrombocytopenic purpura	0.000	0.993	0.007
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.993	0.007
D69.9 Haemorrhagic condition, unspecified	0.000	0.993	0.007
D69.8 Other specified haemorrhagic conditions	0.000	0.993	0.007
D69.4 Other primary thrombocytopenia	0.000	0.993	0.007
D69.1 Qualitative platelet defects	0.000	0.993	0.007
D47.1 Chronic myeloproliferative disease	0.000	0.993	0.007
D47.4 Osteomyelofibrosis	0.000	0.993	0.007
N97 Female infertility	0.007	0.993	0.000
S22.4 Multiple fractures of ribs	0.000	0.994	0.006
N97.0 Female infertility associated with anovulation	0.006	0.994	0.000
Z83 Family history of other specific disorders	0.000	0.995	0.005
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.995	0.005
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.995	0.005
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.995	0.005
H57.1 Ocular pain	0.005	0.995	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.005	0.995	0.000
N97.4 Female infertility associated with male factors	0.005	0.995	0.000
N97.3 Female infertility of cervical origin	0.005	0.995	0.000
N97.2 Female infertility of uterine origin	0.005	0.995	0.000
N97.8 Female infertility of other origin	0.005	0.995	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.995	0.005
Z87.8 Personal history of other specified conditions	0.000	0.995	0.005
D45 Polycythaemia vera	0.000	0.995	0.005
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.995	0.005
Z83.6 Family history of diseases of the respiratory system	0.000	0.996	0.004
H33.3 Retinal breaks without detachment	0.004	0.996	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.996	0.004
R22.3 Localised swelling, mass and lump, upper limb	0.004	0.996	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.996	0.004
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.996	0.004
N97.1 Female infertility of tubal origin	0.004	0.996	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.004	0.996	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.996	0.004
H81.0 Meniere's disease	0.000	0.996	0.004
Z83.3 Family history of diabetes mellitus	0.000	0.996	0.004
H57.8 Other specified disorders of eye and adnexa	0.004	0.996	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
K29.4 Chronic atrophic gastritis	0.004	0.996	0.000
H57 Other disorders of eye and adnexa	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.997	0.003
Z83.7 Family history of diseases of the digestive system	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.997	0.003
H92.1 Otorrhoea	0.000	0.997	0.003
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
G47.3 Sleep apnoea	0.003	0.997	0.000
S01.8 Open wound of other parts of head	0.000	0.997	0.003
S52.6 Fracture of lower end of both ulna and radius	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.003
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
N60.0 Solitary cyst of breast	0.003	0.997	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.997	0.002
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.997	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.997	0.003
S32.30 Fracture of ilium (closed)	0.000	0.997	0.003
C77.1 Intrathoracic lymph nodes	0.003	0.997	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.997	0.003
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.997	0.002
D40.1 Testis	0.000	0.997	0.002
Q60.0 Renal agenesis, unilateral	0.002	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.000	0.998	0.002
Z47.8 Other specified orthopaedic follow-up care	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
S32.3 Fracture of ilium	0.000	0.998	0.002
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.998	0.002
N02.9 Unspecified	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.998	0.002
N89.8 Other specified noninflammatory disorders of vagina	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.998	0.002
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
K38.8 Other specified diseases of appendix	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
D67 Hereditary factor IX deficiency	0.000	0.998	0.002
D66 Hereditary factor VIII deficiency	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.002
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
G47.4 Narcolepsy and cataplexy	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.998	0.002
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.998	0.002
S22.2 Fracture of sternum	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.002
G47 Sleep disorders	0.002	0.998	0.000
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
S22.5 Flail chest	0.000	0.998	0.002
S32.1 Fracture of sacrum	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.998	0.002
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.998	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
I84.5 External haemorrhoids without complication	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.000	0.998	0.002
D40.7 Other male genital organs	0.000	0.998	0.002
G47.9 Sleep disorder, unspecified	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.000	0.998	0.002
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.002	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.998	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.000	0.998	0.002
Q12.0 Congenital cataract	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
I86.1 Scrotal varices	0.000	0.998	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
N39.9 Disorder of urinary system, unspecified	0.000	0.998	0.002
S22.3 Fracture of rib	0.000	0.998	0.002
S36.1 Injury of liver or gallbladder	0.000	0.998	0.002
S36 Injury of intra-abdominal organs	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
I73.0 Raynaud's syndrome	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.998	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.998	0.002
S27.6 Injury of pleura	0.000	0.998	0.002
S27.5 Injury of thoracic trachea	0.000	0.998	0.002
S27.4 Injury of bronchus	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.000	0.998	0.002
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
S21 Open wound of thorax	0.000	0.998	0.002
S22.51 Flail chest (open)	0.000	0.998	0.002
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
D37.7 Other digestive organs	0.000	0.998	0.002
G47.2 Disorders of the sleep-wake schedule	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
S20-S29 Injuries to the thorax	0.000	0.998	0.002
C16.9 Stomach, unspecified	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.002
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.998	0.002
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.002
S36.0 Injury of spleen	0.000	0.998	0.002
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.000	0.998	0.001
D42.1 Spinal meninges	0.000	0.998	0.001
D42.0 Cerebral meninges	0.000	0.998	0.001
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.000	0.998	0.002
S21.9 Open wound of thorax, part unspecified	0.000	0.998	0.002
S27.3 Other injuries of lung	0.000	0.998	0.002
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
M86.94 Osteomyelitis, unspecified (Hand)	0.002	0.998	0.000
D40.0 Prostate	0.000	0.998	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.001
D46 Myelodysplastic syndromes	0.000	0.998	0.002
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.998	0.002
Q12 Congenital lens malformations	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.998	0.002
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.001	0.998	0.000
S32.21 Fracture of coccyx (open)	0.000	0.998	0.001
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.001
D37.3 Appendix	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.998	0.000
S21.2 Open wound of back wall of thorax	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
M10.96 Gout, unspecified (Lower leg)	0.000	0.998	0.002
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
S32.5 Fracture of pubis	0.000	0.998	0.002
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.998	0.002
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.001	0.998	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.001	0.998	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.001	0.998	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.001	0.998	0.000
Q60.6 Potter's syndrome	0.001	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.001
S22.50 Flail chest (closed)	0.000	0.998	0.001
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.000	0.998	0.001
D38.0 Larynx	0.000	0.998	0.001
G47.8 Other sleep disorders	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.001	0.998	0.000
Q14.1 Congenital malformation of retina	0.001	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.000	0.998	0.001
S36.8 Injury of other intra-abdominal organs	0.000	0.998	0.001
S36.7 Injury of multiple intra-abdominal organs	0.000	0.998	0.001
S36.6 Injury of rectum	0.000	0.998	0.001
S36.5 Injury of colon	0.000	0.998	0.001
S36.4 Injury of small intestine	0.000	0.998	0.001
S36.3 Injury of stomach	0.000	0.998	0.001
S36.2 Injury of pancreas	0.000	0.998	0.001
Z51.2 Other chemotherapy	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
H92 Otalgia and effusion of ear	0.000	0.998	0.002
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.001
D38.6 Respiratory organ, unspecified	0.000	0.998	0.001
D38.4 Thymus	0.000	0.998	0.001
D38.3 Mediastinum	0.000	0.998	0.001
D38.2 Pleura	0.000	0.998	0.001
G03.9 Meningitis, unspecified	0.002	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
S32.41 Fracture of acetabulum (open)	0.000	0.998	0.001
D44.3 Pituitary gland	0.000	0.998	0.001
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.001
F43.0 Acute stress reaction	0.000	0.998	0.002
S21.8 Open wound of other parts of thorax	0.000	0.998	0.001
S21.7 Multiple open wounds of thoracic wall	0.000	0.998	0.001
S21.1 Open wound of front wall of thorax	0.000	0.998	0.001
S21.0 Open wound of breast	0.000	0.998	0.001
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.001
Q14 Congenital malformations of posterior segment of eye	0.001	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.001
D37.2 Small intestine	0.000	0.998	0.001
Q38.8 Other congenital malformations of pharynx	0.001	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.998	0.000
Q38.2 Macroglossia	0.001	0.998	0.000
Q38.1 Ankyloglossia	0.001	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.998	0.000
Q77.4 Achondroplasia	0.001	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.998	0.000
D68 Other coagulation defects	0.000	0.998	0.002
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.998	0.001
S26 Injury of heart	0.000	0.998	0.001
S25 Injury of blood vessels of thorax	0.000	0.998	0.001
S24 Injury of nerves and spinal cord at thorax level	0.000	0.998	0.001
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.998	0.001
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.001
S36.01 Injury of spleen (with open wound into cavity)	0.000	0.998	0.001
D44.0 Thyroid gland	0.000	0.998	0.001
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.001	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.001	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.001
I05.0 Mitral stenosis	0.000	0.998	0.001
I67.9 Cerebrovascular disease, unspecified	0.002	0.998	0.000
K76.6 Portal hypertension	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.001	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.000	0.998	0.001
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.000	0.998	0.001
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.000	0.998	0.001
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.000	0.998	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.001
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.001
D44.9 Endocrine gland, unspecified	0.000	0.998	0.001
D44.6 Carotid body	0.000	0.998	0.001
D44.5 Pineal gland	0.000	0.998	0.001
D44.2 Parathyroid gland	0.000	0.998	0.001
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.001
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.001
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.001
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.001
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.001
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.001
H36.0 Diabetic retinopathy	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.001
Q12.9 Congenital lens malformation, unspecified	0.001	0.998	0.000
Q12.8 Other congenital lens malformations	0.001	0.998	0.000
Q12.4 Spherophakia	0.001	0.998	0.000
Q12.3 Congenital aphakia	0.001	0.998	0.000
Q12.2 Coloboma of lens	0.001	0.998	0.000
Q12.1 Congenital displaced lens	0.001	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
S29 Other and unspecified injuries of thorax	0.000	0.998	0.001
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.999	0.001
D38.5 Other respiratory organs	0.000	0.999	0.001
H58.8 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.001	0.999	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.000	0.999	0.001
H72.2 Other marginal perforations of tympanic membrane	0.000	0.999	0.001
H83.0 Labyrinthitis	0.000	0.999	0.001
Q70 Syndactyly	0.001	0.999	0.000
S37 Injury of urinary and pelvic organs	0.000	0.999	0.001
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.999	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
D37.9 Digestive organ, unspecified	0.000	0.999	0.001
D37.1 Stomach	0.000	0.999	0.001
D39.9 Female genital organ, unspecified	0.000	0.999	0.001
D39.7 Other female genital organs	0.000	0.999	0.001
D39.2 Placenta	0.000	0.999	0.001
D43.9 Central nervous system, unspecified	0.000	0.999	0.001
D43.7 Other parts of central nervous system	0.000	0.999	0.001
D43.4 Spinal cord	0.000	0.999	0.001
D43.3 Cranial nerves	0.000	0.999	0.001
J94.8 Other specified pleural conditions	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.000	0.999	0.001
Q76.0 Spina bifida occulta	0.001	0.999	0.000
M86 Osteomyelitis	0.001	0.999	0.000
F99-F99 Unspecified mental disorder	0.000	0.999	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
M86.98 Osteomyelitis, unspecified (Other)	0.001	0.999	0.000
M89.38 Hypertrophy of bone (Other)	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.000	0.999	0.001
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.999	0.001
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
Q70.3 Webbed toes	0.001	0.999	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.999	0.001
M89 Other disorders of bone	0.001	0.999	0.000
Q43 Other congenital malformations of intestine	0.001	0.999	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.999	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.000	0.999	0.001
S36.20 Injury of pancreas (without open wound into cavity)	0.000	0.999	0.001
S36.31 Injury of stomach (with open wound into cavity)	0.000	0.999	0.001
S36.30 Injury of stomach (without open wound into cavity)	0.000	0.999	0.001
S36.41 Injury of small intestine (with open wound into cavity)	0.000	0.999	0.001
S36.40 Injury of small intestine (without open wound into cavity)	0.000	0.999	0.001
S36.51 Injury of colon (with open wound into cavity)	0.000	0.999	0.001
S36.50 Injury of colon (without open wound into cavity)	0.000	0.999	0.001
S36.61 Injury of rectum (with open wound into cavity)	0.000	0.999	0.001
S36.60 Injury of rectum (without open wound into cavity)	0.000	0.999	0.001
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.000	0.999	0.001
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.000	0.999	0.001
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.000	0.999	0.001
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.000	0.999	0.001
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.000	0.999	0.001
F81.9 Developmental disorder of scholastic skills, unspecified	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
Q17 Other congenital malformations of ear	0.001	0.999	0.000
Q40 Other congenital malformations of upper alimentary tract	0.001	0.999	0.000
M25.84 Other specified joint disorders (Hand)	0.001	0.999	0.000
M89.84 Other specified disorders of bone (Hand)	0.001	0.999	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.999	0.001
D44.8 Pluriglandular involvement	0.000	0.999	0.001
D44.1 Adrenal gland	0.000	0.999	0.001
D68.1 Hereditary factor XI deficiency	0.000	0.999	0.001
J37.0 Chronic laryngitis	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.000	0.999	0.001
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.001	0.999	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.999	0.001
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
F43.1 Posttraumatic stress disorder	0.000	0.999	0.001
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.001	0.999	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.001	0.999	0.000
Q14.3 Congenital malformation of choroid	0.001	0.999	0.000
Q14.2 Congenital malformation of optic disk	0.001	0.999	0.000
Q14.0 Congenital malformation of vitreous humour	0.001	0.999	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.000	0.999	0.001
Q45 Other congenital malformations of digestive system	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.999	0.000
S52.30 Fracture of shaft of radius (closed)	0.001	0.999	0.000
D43.0 Brain, supratentorial	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.000	0.999	0.001
Q63.2 Ectopic kidney	0.001	0.999	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.999	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.999	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.999	0.000
Q77.5 Diastrophic dysplasia	0.001	0.999	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.999	0.000
Q77.2 Short rib syndrome	0.001	0.999	0.000
Q77.1 Thanatophoric short stature	0.001	0.999	0.000
Q77.0 Achondrogenesis	0.001	0.999	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.999	0.001
S23.4 Sprain and strain of ribs and sternum	0.000	0.999	0.001
S23.3 Sprain and strain of thoracic spine	0.000	0.999	0.001
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.999	0.001
S23.1 Dislocation of thoracic vertebra	0.000	0.999	0.001
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.999	0.001
S24.6 Injury of unspecified nerve of thorax	0.000	0.999	0.001
S24.5 Injury of other nerves of thorax	0.000	0.999	0.001
S24.4 Injury of thoracic sympathetic nerves	0.000	0.999	0.001
S24.3 Injury of peripheral nerves of thorax	0.000	0.999	0.001
S24.2 Injury of nerve root of thoracic spine	0.000	0.999	0.001
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.999	0.001
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.999	0.001
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.999	0.001
S25.8 Injury of other blood vessels of thorax	0.000	0.999	0.001
S25.7 Injury of multiple blood vessels of thorax	0.000	0.999	0.001
S25.5 Injury of intercostal blood vessels	0.000	0.999	0.001
S25.4 Injury of pulmonary blood vessels	0.000	0.999	0.001
S25.3 Injury of innominate or subclavian vein	0.000	0.999	0.001
S25.2 Injury of superior vena cava	0.000	0.999	0.001
S25.1 Injury of innominate or subclavian artery	0.000	0.999	0.001
S25.0 Injury of thoracic aorta	0.000	0.999	0.001
S26.9 Injury of heart, unspecified	0.000	0.999	0.001
S26.8 Other injuries of heart	0.000	0.999	0.001
S26.0 Injury of heart with haemopericardium	0.000	0.999	0.001
S28.1 Traumatic amputation of part of thorax	0.000	0.999	0.001
S28.0 Crushed chest	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.999	0.001
Q18 Other congenital malformations of face and neck	0.001	0.999	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.999	0.000
Q15 Other congenital malformations of eye	0.001	0.999	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.999	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.999	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations