TreeWAS – Variant ID: rs1361831

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I10-I15 Hypertensive diseases	0.541	0.459	0.000
I11 Hypertensive heart disease	0.441	0.559	0.000
I13 Hypertensive heart and renal disease	0.431	0.569	0.000
I15 Secondary hypertension	0.385	0.615	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.375	0.625	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.340	0.660	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.328	0.672	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.309	0.691	0.000
I15.0 Renovascular hypertension	0.309	0.691	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.308	0.692	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.306	0.694	0.000
I15.2 Hypertension secondary to endocrine disorders	0.284	0.716	0.000
I15.9 Seconday hypertension, unspecified	0.283	0.717	0.000
I12 Hypertensive renal disease	0.278	0.722	0.000
I15.8 Other secondary hypertension	0.276	0.724	0.000
S02.20 Fracture of nasal bones (closed)	0.271	0.729	0.000
I15.1 Hypertension secondary to other renal disorders	0.203	0.797	0.000
I12.0 Hypertensive renal disease with renal failure	0.203	0.797	0.000
S02.2 Fracture of nasal bones	0.161	0.839	0.000
I67 Other cerebrovascular diseases	0.146	0.854	0.000
I60-I69 Cerebrovascular diseases	0.143	0.857	0.000
I67.1 Cerebral aneurysm, nonruptured	0.140	0.860	0.000
I63 Cerebral infarction	0.139	0.861	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.136	0.864	0.000
Chapter IX Diseases of the circulatory system	0.136	0.864	0.000
I67.2 Cerebral atherosclerosis	0.135	0.865	0.000
I60 Subarachnoid haemorrhage	0.131	0.869	0.000
I67.9 Cerebrovascular disease, unspecified	0.128	0.872	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.128	0.872	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.126	0.874	0.000
I63.8 Other cerebral infarction	0.126	0.874	0.000
I05-I09 Chronic rheumatic heart diseases	0.125	0.875	0.000
I08.0 Disorders of both mitral and aortic valves	0.122	0.878	0.000
S02.21 Fracture of nasal bones (open)	0.121	0.879	0.000
I08 Multiple valve diseases	0.121	0.879	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.116	0.884	0.000
I67.4 Hypertensive encephalopathy	0.111	0.889	0.000
I00-I02 Acute rheumatic fever	0.110	0.890	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.106	0.894	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.105	0.895	0.000
I67.5 Moyamoya disease	0.105	0.895	0.000
I67.3 Progressive vascular leukoencephalopathy	0.105	0.895	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.104	0.896	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.104	0.896	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.103	0.897	0.000
I09 Other rheumatic heart diseases	0.103	0.897	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.101	0.899	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.100	0.900	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.100	0.900	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.099	0.901	0.000
I62 Other nontraumatic intracranial haemorrhage	0.097	0.903	0.000
I60.8 Other subarachnoid haemorrhage	0.097	0.903	0.000
I61 Intracerebral haemorrhage	0.097	0.903	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.096	0.904	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.096	0.904	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.095	0.904	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.094	0.906	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.092	0.908	0.000
I00 Rheumatic fever without mention of heart involvement	0.091	0.909	0.000
I06 Rheumatic aortic valve diseases	0.089	0.911	0.000
I08.8 Other multiple valve diseases	0.088	0.912	0.000
I09.9 Rheumatic heart disease, unspecified	0.087	0.913	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.086	0.914	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.086	0.914	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.085	0.915	0.000
I67.8 Other specified cerebrovascular diseases	0.084	0.916	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.082	0.917	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.083	0.917	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.082	0.918	0.000
I12.9 Hypertensive renal disease without renal failure	0.081	0.919	0.000
I07 Rheumatic tricuspid valve diseases	0.081	0.919	0.000
I02 Rheumatic chorea	0.079	0.921	0.000
I01 Rheumatic fever with heart involvement	0.079	0.921	0.000
I61.8 Other intracerebral haemorrhage	0.078	0.922	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.074	0.926	0.000
I09.8 Other specified rheumatic heart diseases	0.074	0.926	0.000
I09.2 Chronic rheumatic pericarditis	0.074	0.926	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.074	0.926	0.000
I09.0 Rheumatic myocarditis	0.074	0.926	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.073	0.927	0.000
I65.1 Occlusion and stenosis of basilar artery	0.073	0.927	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.073	0.927	0.000
K61.0 Anal abscess	0.000	0.928	0.072
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.072	0.928	0.000
S02 Fracture of skull and facial bones	0.072	0.928	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.071	0.929	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.071	0.929	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.071	0.929	0.000
I08.9 Multiple valve disease, unspecified	0.071	0.929	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.069	0.931	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.069	0.931	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.068	0.932	0.000
I06.0 Rheumatic aortic stenosis	0.068	0.932	0.000
I68.0 Cerebral amyloid angiopathy	0.067	0.933	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.066	0.934	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.065	0.935	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.065	0.935	0.000
I69 Sequelae of cerebrovascular disease	0.065	0.935	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.064	0.935	0.000
I06.8 Other rheumatic aortic valve diseases	0.064	0.936	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.064	0.936	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.063	0.937	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.062	0.938	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.062	0.938	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.062	0.938	0.000
I62.1 Nontraumatic extradural haemorrhage	0.062	0.938	0.000
S02.7 Multiple fractures involving skull and facial bones	0.061	0.939	0.000
I05 Rheumatic mitral valve diseases	0.060	0.940	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.059	0.941	0.000
I06.1 Rheumatic aortic insufficiency	0.058	0.941	0.000
I07.9 Tricuspid valve disease, unspecified	0.058	0.941	0.000
I07.8 Other tricuspid valve diseases	0.058	0.941	0.000
I07.2 Tricuspid stenosis with insufficiency	0.058	0.941	0.000
I07.0 Tricuspid stenosis	0.058	0.941	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.058	0.942	0.000
S02.5 Fracture of tooth	0.058	0.942	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.057	0.943	0.000
S02.8 Fractures of other skull and facial bones	0.057	0.943	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.057	0.943	0.000
I01.8 Other acute rheumatic heart disease	0.057	0.943	0.000
I01.2 Acute rheumatic myocarditis	0.057	0.943	0.000
I01.1 Acute rheumatic endocarditis	0.057	0.943	0.000
I01.0 Acute rheumatic pericarditis	0.057	0.943	0.000
I02.9 Rheumatic chorea without heart involvement	0.057	0.943	0.000
I02.0 Rheumatic chorea with heart involvement	0.057	0.943	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.057	0.943	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.054	0.945	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.054	0.946	0.000
S02.0 Fracture of vault of skull	0.053	0.946	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.053	0.947	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.053	0.947	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.053	0.947	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.053	0.947	0.000
I07.1 Tricuspid insufficiency	0.050	0.950	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.049	0.951	0.000
S02.50 Fracture of tooth (closed)	0.047	0.953	0.000
S02.1 Fracture of base of skull	0.047	0.953	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.047	0.953	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.046	0.954	0.000
S02.4 Fracture of malar and maxillary bones	0.046	0.954	0.000
I05.0 Mitral stenosis	0.046	0.954	0.000
I05.8 Other mitral valve diseases	0.045	0.955	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.044	0.955	0.000
S02.6 Fracture of mandible	0.044	0.955	0.000
I95 Hypotension	0.044	0.956	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.044	0.956	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.043	0.957	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.043	0.957	0.000
I99 Other and unspecified disorders of circulatory system	0.043	0.957	0.000
I95.2 Hypotension due to drugs	0.042	0.958	0.000
S02.51 Fracture of tooth (open)	0.041	0.958	0.000
S02.81 Fractures of other skull and facial bones (open)	0.041	0.959	0.000
S02.00 Fracture of vault of skull (closed)	0.040	0.960	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.040	0.960	0.000
I69.3 Sequelae of cerebral infarction	0.040	0.960	0.000
S02.3 Fracture of orbital floor	0.039	0.960	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.039	0.961	0.000
S02.01 Fracture of vault of skull (open)	0.038	0.961	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.038	0.961	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.038	0.962	0.000
I95.8 Other hypotension	0.038	0.962	0.000
I05.9 Mitral valve disease, unspecified	0.037	0.963	0.000
I97.1 Other functional disturbances following cardiac surgery	0.037	0.963	0.000
I05.2 Mitral stenosis with insufficiency	0.037	0.963	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.035	0.964	0.000
I97.0 Postcardiotomy syndrome	0.035	0.965	0.000
S02.10 Fracture of base of skull (closed)	0.035	0.965	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.033	0.966	0.000
S02.61 Fracture of mandible (open)	0.032	0.968	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.031	0.969	0.001
I05.1 Rheumatic mitral insufficiency	0.031	0.969	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.030	0.970	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.030	0.970	0.000
S02.11 Fracture of base of skull (open)	0.028	0.971	0.000
S02.31 Fracture of orbital floor (open)	0.028	0.971	0.000
I28 Other diseases of pulmonary vessels	0.027	0.972	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.027	0.973	0.000
S02.60 Fracture of mandible (closed)	0.025	0.975	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.023	0.977	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.022	0.977	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.022	0.977	0.001
I98.0 Cardiovascular syphilis	0.022	0.977	0.001
N83.2 Other and unspecified ovarian cysts	0.022	0.978	0.000
I95.0 Idiopathic hypotension	0.022	0.978	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.022	0.978	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.021	0.979	0.000
I95.1 Orthostatic hypotension	0.020	0.980	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.020	0.980	0.000
I28.1 Aneurysm of pulmonary artery	0.020	0.980	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.020	0.980	0.000
I28.8 Other specified diseases of pulmonary vessels	0.020	0.980	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.018	0.982	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.016	0.984	0.000
S02.30 Fracture of orbital floor (closed)	0.016	0.984	0.000
I77.6 Arteritis, unspecified	0.000	0.984	0.016
S83.6 Sprain and strain of other and unspecified parts of knee	0.016	0.984	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.015	0.985	0.000
I49.8 Other specified cardiac arrhythmias	0.015	0.985	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.015	0.985	0.000
K61 Abscess of anal and rectal regions	0.000	0.985	0.015
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.015	0.985	0.000
I89.1 Lymphangitis	0.014	0.986	0.000
S83.3 Tear of articular cartilage of knee, current	0.014	0.986	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.013	0.987	0.000
S83.0 Dislocation of patella	0.013	0.987	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.013	0.987	0.000
I26 Pulmonary embolism	0.013	0.987	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.013	0.987	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.012	0.987	0.000
I72 Other aneurysm	0.012	0.988	0.000
I70 Atherosclerosis	0.012	0.988	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.012	0.988	0.000
K61.4 Intrasphincteric abscess	0.000	0.988	0.012
S83.1 Dislocation of knee	0.012	0.988	0.000
H02.0 Entropion and trichiasis of eyelid	0.012	0.988	0.000
I65.2 Occlusion and stenosis of carotid artery	0.012	0.988	0.000
S83.7 Injury to multiple structures of knee	0.011	0.989	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.011	0.989	0.000
I88 Nonspecific lymphadenitis	0.011	0.989	0.000
I49 Other cardiac arrhythmias	0.011	0.989	0.000
I49.9 Cardiac arrhythmia, unspecified	0.011	0.989	0.000
I79.1 Aortitis in diseases classified elsewhere	0.011	0.989	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.011	0.989	0.000
I70.1 Atherosclerosis of renal artery	0.011	0.989	0.000
I72.0 Aneurysm of carotid artery	0.011	0.989	0.000
I49.1 Atrial premature depolarisation	0.011	0.989	0.000
I72.4 Aneurysm of artery of lower extremity	0.010	0.989	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.989	0.011
K61.2 Anorectal abscess	0.000	0.989	0.010
I70.10 Atherosclerosis of renal artery (without gangrene)	0.010	0.990	0.000
I88.8 Other nonspecific lymphadenitis	0.010	0.990	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.010	0.990	0.000
N83.6 Haematosalpinx	0.010	0.990	0.000
I83 Varicose veins of lower extremities	0.010	0.990	0.000
K08.3 Retained dental root	0.010	0.990	0.000
I70.0 Atherosclerosis of aorta	0.010	0.990	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.010	0.990	0.000
K61.1 Rectal abscess	0.000	0.990	0.009
I72.9 Aneurysm of unspecified site	0.009	0.991	0.000
I70.8 Atherosclerosis of other arteries	0.009	0.991	0.000
I72.3 Aneurysm of iliac artery	0.009	0.991	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.009	0.991	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.009	0.991	0.000
I70.9 Generalised and unspecified atherosclerosis	0.009	0.991	0.000
I72.8 Aneurysm of other specified arteries	0.009	0.991	0.000
I27 Other pulmonary heart diseases	0.009	0.991	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.008	0.992	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.008	0.992	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.008	0.992	0.000
N83.7 Haematoma of broad ligament	0.008	0.992	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.008	0.992	0.000
N83.1 Corpus luteum cyst	0.008	0.992	0.000
I87 Other disorders of veins	0.008	0.992	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.008	0.992	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.008	0.992	0.000
S83.2 Tear of meniscus, current	0.008	0.992	0.000
I49.2 Junctional premature depolarisation	0.008	0.992	0.000
I72.2 Aneurysm of renal artery	0.008	0.992	0.000
K08 Other disorders of teeth and supporting structures	0.008	0.992	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.008	0.992	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.008	0.992	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.008	0.992	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.007	0.993	0.000
I49.0 Ventricular fibrillation and flutter	0.007	0.993	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.007	0.993	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.007	0.993	0.000
I72.1 Aneurysm of artery of upper extremity	0.007	0.993	0.000
I30-I52 Other forms of heart disease	0.007	0.993	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.007	0.993	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.007	0.993	0.000
N83.0 Follicular cyst of ovary	0.007	0.993	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.007	0.993	0.000
I73.0 Raynaud's syndrome	0.000	0.993	0.007
M34.9 Systemic sclerosis, unspecified	0.000	0.993	0.007
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.006	0.993	0.000
I33 Acute and subacute endocarditis	0.006	0.993	0.000
I82 Other venous embolism and thrombosis	0.006	0.993	0.000
I27.1 Kyphoscoliotic heart disease	0.006	0.993	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
R49.8 Other and unspecified voice disturbances	0.000	0.994	0.006
I85 Oesophageal varices	0.003	0.994	0.003
I33.0 Acute and subacute infective endocarditis	0.006	0.994	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.006	0.994	0.000
I36 Nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
I27.9 Pulmonary heart disease, unspecified	0.006	0.994	0.000
I87.0 Postphlebitic syndrome	0.006	0.994	0.000
I30 Acute pericarditis	0.006	0.994	0.000
I49.3 Ventricular premature depolarisation	0.006	0.994	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.006	0.994	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.006	0.994	0.000
I87.1 Compression of vein	0.006	0.994	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.006	0.994	0.000
I27.8 Other specified pulmonary heart diseases	0.006	0.994	0.000
I87.8 Other specified disorders of veins	0.006	0.994	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.006	0.994	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.006	0.994	0.000
I30.1 Infective pericarditis	0.006	0.994	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.994	0.006
I82.3 Embolism and thrombosis of renal vein	0.006	0.994	0.000
I38 Endocarditis, valve unspecified	0.006	0.994	0.000
O48 Prolonged pregnancy	0.000	0.994	0.006
I52 Other heart disorders in diseases classified elsewhere	0.005	0.994	0.000
I48 Atrial fibrillation and flutter	0.005	0.994	0.000
I41 Myocarditis in diseases classified elsewhere	0.005	0.994	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.005	0.994	0.000
I32 Pericarditis in diseases classified elsewhere	0.005	0.994	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.005	0.994	0.000
I87.9 Disorder of vein, unspecified	0.005	0.995	0.000
I37 Pulmonary valve disorders	0.005	0.995	0.000
I50.1 Left ventricular failure	0.005	0.995	0.000
R49.0 Dysphonia	0.000	0.995	0.005
Q12.0 Congenital cataract	0.005	0.995	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.005	0.995	0.000
Q54.0 Hypospadias, balanic	0.000	0.995	0.005
Z57.2 Occupational exposure to dust	0.005	0.995	0.000
N50.9 Disorder of male genital organs, unspecified	0.000	0.995	0.005
N50 Other disorders of male genital organs	0.000	0.995	0.005
I83.1 Varicose veins of lower extremities with inflammation	0.005	0.995	0.000
I82.8 Embolism and thrombosis of other specified veins	0.005	0.995	0.000
I82.1 Thrombophlebitis migrans	0.005	0.995	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.004	0.995	0.001
I78 Diseases of capillaries	0.005	0.995	0.000
R59.0 Localised enlarged lymph nodes	0.005	0.995	0.000
I40 Acute myocarditis	0.005	0.995	0.000
I50 Heart failure	0.005	0.995	0.000
M34 Systemic sclerosis	0.000	0.995	0.005
I30.8 Other forms of acute pericarditis	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
Q54 Hypospadias	0.000	0.995	0.005
D32.0 Cerebral meninges	0.005	0.995	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.005	0.995	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.005	0.995	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.005	0.995	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.005	0.995	0.000
I46 Cardiac arrest	0.005	0.995	0.000
R49 Voice disturbances	0.000	0.995	0.005
I30.0 Acute nonspecific idiopathic pericarditis	0.005	0.995	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.995	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.995	0.005
Q54.9 Hypospadias, unspecified	0.000	0.995	0.005
D32.9 Meninges, unspecified	0.004	0.995	0.000
I20-I25 Ischaemic heart diseases	0.004	0.996	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
N64.5 Other signs and symptoms in breast	0.000	0.996	0.004
I33.9 Acute endocarditis, unspecified	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.004	0.996	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.004	0.996	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.004	0.996	0.000
I37.1 Pulmonary valve insufficiency	0.004	0.996	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.004	0.996	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.004	0.996	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.004	0.996	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.004	0.996	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.004	0.996	0.000
I48.4 Atypical atrial flutter	0.004	0.996	0.000
I48.3 Typical atrial flutter	0.004	0.996	0.000
I48.2 Chronic atrial fibrillation	0.004	0.996	0.000
I48.1 Persistent atrial fibrillation	0.004	0.996	0.000
I48.0 Paroxysmal atrial fibrillation	0.004	0.996	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.004	0.996	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.004	0.996	0.000
N50.0 Atrophy of testis	0.000	0.996	0.004
I82.0 Budd-Chiari syndrome	0.004	0.996	0.000
M34.1 CR(E)ST syndrome	0.000	0.996	0.004
I37.9 Pulmonary valve disorder, unspecified	0.004	0.996	0.000
I37.8 Other pulmonary valve disorders	0.004	0.996	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.004	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.004	0.996	0.000
I49.5 Sick sinus syndrome	0.004	0.996	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.004	0.996	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.004	0.996	0.000
I37.0 Pulmonary valve stenosis	0.004	0.996	0.000
I85.0 Oesophageal varices with bleeding	0.001	0.996	0.003
I73 Other peripheral vascular diseases	0.003	0.996	0.001
I30.9 Acute pericarditis, unspecified	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
I34 Nonrheumatic mitral valve disorders	0.004	0.996	0.000
Q54.1 Hypospadias, penile	0.000	0.996	0.004
I22.9 Subsequent myocardial infarction of unspecified site	0.004	0.996	0.000
I40.8 Other acute myocarditis	0.004	0.996	0.000
I40.1 Isolated myocarditis	0.004	0.996	0.000
M34.0 Progressive systemic sclerosis	0.000	0.996	0.004
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.004	0.996	0.000
D32 Benign neoplasm of meninges	0.004	0.996	0.000
I40.9 Acute myocarditis, unspecified	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
L50.8 Other urticaria	0.000	0.996	0.004
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.996	0.004
Q54.8 Other hypospadias	0.000	0.996	0.004
Q54.4 Congenital chordee	0.000	0.996	0.004
Q54.3 Hypospadias, perineal	0.000	0.996	0.004
Q54.2 Hypospadias, penoscrotal	0.000	0.996	0.004
I81 Portal vein thrombosis	0.003	0.996	0.000
I46.9 Cardiac arrest, unspecified	0.004	0.996	0.000
K61.3 Ischiorectal abscess	0.000	0.996	0.003
I46.1 Sudden cardiac death, so described	0.004	0.996	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.004	0.996	0.000
R49.2 Hypernasality and hyponasality	0.000	0.996	0.004
I34.1 Mitral (valve) prolapse	0.004	0.996	0.000
N18.3 Chronic kidney disease, stage 3	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
I63.9 Cerebral infarction, unspecified	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.996	0.000
M16.0 Primary coxarthrosis, bilateral	0.004	0.996	0.000
H02.8 Other specified disorders of eyelid	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.000	0.996	0.004
Q51.2 Other doubling of uterus	0.000	0.996	0.003
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.003	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.997	0.003
I23 Certain current complications following acute myocardial infarction	0.003	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.001
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
I22 Subsequent myocardial infarction	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.000	0.997	0.003
Q12 Congenital lens malformations	0.003	0.997	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.003	0.997	0.000
I40.0 Infective myocarditis	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.000	0.997	0.003
I34.8 Other nonrheumatic mitral valve disorders	0.003	0.997	0.000
Q53 Undescended testicle	0.000	0.997	0.003
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.997	0.003
I89.0 Lymphoedema, not elsewhere classified	0.003	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
I80 Phlebitis and thrombophlebitis	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.997	0.003
L50 Urticaria	0.000	0.997	0.003
M54.29 Cervicalgia-Site unspe	0.000	0.997	0.003
I77 Other disorders of arteries and arterioles	0.002	0.997	0.001
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.997	0.003
S72.20 Subtrochanteric fracture (closed)	0.003	0.997	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
I35 Nonrheumatic aortic valve disorders	0.003	0.997	0.000
L50.0 Allergic urticaria	0.000	0.997	0.003
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.997	0.003
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.997	0.003
I74.0 Embolism and thrombosis of abdominal aorta	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.000	0.997	0.003
I73.8 Other specified peripheral vascular diseases	0.002	0.997	0.001
Q52.1 Doubling of vagina	0.000	0.997	0.003
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
W18.3 Sports and athletics area	0.003	0.997	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
D32.1 Spinal meninges	0.003	0.997	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.003	0.997	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.003	0.997	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.003	0.997	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.003	0.997	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.003	0.997	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.003	0.997	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.997	0.003
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.997	0.003
Q51.6 Embryonic cyst of cervix	0.000	0.997	0.003
Q51.5 Agenesis and aplasia of cervix	0.000	0.997	0.003
Q51.4 Unicornate uterus	0.000	0.997	0.003
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.997	0.003
Q51.0 Agenesis and aplasia of uterus	0.000	0.997	0.003
Q52.5 Fusion of labia	0.000	0.997	0.003
I74.8 Embolism and thrombosis of other arteries	0.003	0.997	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.997	0.003
R49.1 Aphonia	0.000	0.997	0.002
R52.0 Acute pain	0.000	0.997	0.003
H02 Other disorders of eyelid	0.003	0.997	0.000
I86 Varicose veins of other sites	0.002	0.997	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.003	0.997	0.000
I95.9 Hypotension, unspecified	0.003	0.997	0.000
I23.8 Other current complications following acute myocardial infarction	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.000	0.997	0.003
I31 Other diseases of pericardium	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.003	0.997	0.000
S52.50 Fracture of lower end of radius (closed)	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.000	0.997	0.002
L50.1 Idiopathic urticaria	0.000	0.997	0.003
Q12.9 Congenital lens malformation, unspecified	0.002	0.997	0.000
Q12.8 Other congenital lens malformations	0.002	0.997	0.000
Q12.4 Spherophakia	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations