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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1362073
log Bayes Factor = 37.8177
Chromosome 6   position 29,383,320  (GRCh37) Explore rs1362073 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.008 0.992
E10.3 With ophthalmic complications
0.000 0.019 0.981
E10.9 Without complications
0.000 0.027 0.973
E10.2 With renal complications
0.000 0.035 0.965
E10.1 With ketoacidosis
0.000 0.059 0.941
E10-E14 Diabetes mellitus
0.000 0.089 0.911
E10.4 With neurological complications
0.000 0.108 0.892
E13 Other specified diabetes mellitus
0.000 0.116 0.884
E13.9 Without complications
0.000 0.135 0.865
E10.0 With coma
0.000 0.211 0.789
E10.6 With other specified complications
0.000 0.256 0.744
E10.5 With peripheral circulatory complications
0.000 0.269 0.731
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.346 0.653
E14 Unspecified diabetes mellitus
0.000 0.348 0.652
E13.8 With unspecified complications
0.000 0.366 0.634
E13.7 With multiple complications
0.000 0.366 0.634
E13.6 With other specified complications
0.000 0.366 0.634
E13.5 With peripheral circulatory complications
0.000 0.366 0.634
E13.4 With neurological complications
0.000 0.366 0.634
E13.2 With renal complications
0.000 0.366 0.634
E13.1 With ketoacidosis
0.000 0.366 0.634
E13.0 With coma
0.000 0.366 0.634
E13.3 With ophthalmic complications
0.000 0.370 0.630
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.418 0.582
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.424 0.576
E16 Other disorders of pancreatic internal secretion
0.000 0.428 0.572
E16.2 Hypoglycaemia, unspecified
0.000 0.431 0.569
E00-E07 Disorders of thyroid gland
0.000 0.458 0.542
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.461 0.539
E05.9 Thyrotoxicosis, unspecified
0.000 0.467 0.533
E10.8 With unspecified complications
0.000 0.476 0.524
E14.2 Withrenal complications
0.000 0.494 0.506
E11 Non-insulin-dependent diabetes mellitus
0.000 0.505 0.495
E14.4 With neurological complications
0.000 0.508 0.492
K90 Intestinal malabsorption
0.000 0.511 0.489
E16.1 Other hypoglycaemia
0.000 0.515 0.485
E14.8 With unspecified complications
0.000 0.524 0.476
E14.9 Without complications
0.000 0.526 0.474
E12.9 Without complications
0.000 0.531 0.468
E12.8 With unspecified complications
0.000 0.531 0.468
E12.7 With multiple complications
0.000 0.531 0.468
E12.6 With other specified complications
0.000 0.531 0.468
E12.5 With peripheral circulatory complications
0.000 0.531 0.468
E12.4 With neurological complications
0.000 0.531 0.468
E12.3 With ophthalmic complications
0.000 0.531 0.468
E12.2 With renal complications
0.000 0.531 0.468
E12.1 With ketoacidosis
0.000 0.531 0.468
E12.0 With coma
0.000 0.531 0.468
E14.7 With multiple complications
0.000 0.532 0.468
E14.6 With other specified complications
0.000 0.532 0.468
E14.5 With peripheral circulatory complications
0.000 0.532 0.468
E14.0 With coma
0.000 0.532 0.468
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.533 0.467
E14.1 With ketoacidosis
0.000 0.534 0.466
E05.8 Other thyrotoxicosis
0.000 0.541 0.459
E11.2 With renal complications
0.000 0.548 0.452
E11.0 With coma
0.000 0.573 0.427
E15 Nondiabetic hypoglycaemic coma
0.000 0.587 0.413
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.589 0.410
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.589 0.410
E16.4 Abnormal secretion of gastrin
0.000 0.589 0.410
E16.3 Increased secretion of glucagon
0.000 0.589 0.410
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.598 0.402
E11.6 With other specified complications
0.000 0.601 0.399
E40-E46 Malnutrition
0.000 0.604 0.395
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.611 0.389
E00 Congenital iodine-deficiency syndrome
0.000 0.611 0.389
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.612 0.387
E05.5 Thyroid crisis or storm
0.000 0.613 0.386
E05.4 Thyrotoxicosis factitia
0.000 0.613 0.386
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.613 0.386
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.630 0.370
E14.3 With ophthalmic complications
0.000 0.640 0.360
E11.7 With multiple complications
0.000 0.645 0.355
K90.3 Pancreatic steatorrhoea
0.000 0.649 0.351
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.649 0.351
K90.1 Tropical sprue
0.000 0.649 0.351
K90.9 Intestinal malabsorption, unspecified
0.000 0.650 0.350
E11.1 With ketoacidosis
0.000 0.653 0.347
E07 Other disorders of thyroid
0.000 0.656 0.344
K90.8 Other intestinal malabsorption
0.000 0.660 0.340
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.670 0.329
E11.4 With neurological complications
0.000 0.688 0.312
E11.5 With peripheral circulatory complications
0.000 0.692 0.308
E03 Other hypothyroidism
0.000 0.694 0.306
E04 Other non-toxic goitre
0.000 0.695 0.305
E11.8 With unspecified complications
0.000 0.701 0.299
E04.9 Non-toxic goitre, unspecified
0.000 0.702 0.297
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.703 0.297
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.716 0.284
E45 Retarded development following protein-energy malnutrition
0.000 0.716 0.284
E43 Unspecified severe protein-energy malnutrition
0.000 0.716 0.284
E42 Marasmic kwashiorkor
0.000 0.716 0.284
E41 Nutritional marasmus
0.000 0.716 0.284
E40 Kwashiorkor
0.000 0.716 0.284
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.721 0.279
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.721 0.279
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.721 0.279
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.721 0.279
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.721 0.279
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.721 0.279
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.721 0.279
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.721 0.279
K51 Ulcerative colitis
0.279 0.721 0.000
E50-E64 Other nutritional deficiencies
0.000 0.726 0.274
E06 Thyroiditis
0.000 0.727 0.273
K51.4 Pseudopolyposis of colon
0.270 0.730 0.000
E07.8 Other specified disorders of thyroid
0.000 0.730 0.270
K51.9 Ulcerative colitis, unspecified
0.269 0.731 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.264 0.736 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.738 0.262
K51.2 Ulcerative (chronic) proctitis
0.259 0.741 0.000
E07.1 Dyshormogenetic goitre
0.000 0.753 0.247
E07.0 Hypersecretion of calcitonin
0.000 0.753 0.247
E20-E35 Disorders of other endocrine glands
0.000 0.757 0.243
E03.8 Other specified hypothyroidism
0.000 0.759 0.241
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.768 0.232
K51.0 Ulcerative (chronic) enterocolitis
0.232 0.768 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.768 0.232
E03.5 Myxoedema coma
0.000 0.780 0.220
E03.4 Atrophy of thyroid (acquired)
0.000 0.780 0.220
E03.3 Postinfectious hypothyroidism
0.000 0.780 0.220
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.780 0.220
E04.8 Other specified non-toxic goitre
0.000 0.781 0.219
E23 Hypofunction and other disorders of pituitary gland
0.000 0.784 0.216
E06.9 Thyroiditis, unspecified
0.000 0.784 0.216
E51 Thiamine deficiency
0.000 0.785 0.214
K51.1 Ulcerative (chronic) ileocolitis
0.207 0.793 0.000
E56 Other vitamin deficiencies
0.000 0.796 0.204
K51.5 Mucosal proctocolitis
0.204 0.796 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.796 0.203
E44.0 Moderate protein-energy malnutrition
0.000 0.796 0.203
K51.8 Other ulcerative colitis
0.202 0.798 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.799 0.201
E24 Cushing's syndrome
0.000 0.801 0.199
E20 Hypoparathyroidism
0.000 0.803 0.197
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.803 0.197
E63 Other nutritional deficiencies
0.000 0.803 0.197
E50 Vitamin A deficiency
0.000 0.803 0.197
E60 Dietary zinc deficiency
0.000 0.803 0.197
E59 Dietary selenium deficiency
0.000 0.803 0.197
E54 Ascorbic acid deficiency
0.000 0.803 0.197
E52 Niacin deficiency [pellagra]
0.000 0.803 0.197
E06.4 Drug-induced thyroiditis
0.000 0.804 0.196
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.804 0.196
E06.1 Subacute thyroiditis
0.000 0.804 0.196
E06.0 Acute thyroiditis
0.000 0.804 0.196
E23.2 Diabetes insipidus
0.000 0.809 0.191
E83 Disorders of mineral metabolism
0.188 0.812 0.000
E23.0 Hypopituitarism
0.000 0.812 0.188
E29 Testicular dysfunction
0.000 0.825 0.175
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.826 0.174
E32 Diseases of thymus
0.000 0.826 0.174
E30 Disorders of puberty, not elsewhere classified
0.000 0.826 0.174
E25 Adrenogenital disorders
0.000 0.826 0.174
E53 Deficiency of other B group vitamins
0.000 0.827 0.173
E51.2 Wernicke's encephalopathy
0.000 0.828 0.172
E58 Dietary calcium deficiency
0.000 0.829 0.171
E20.9 Hypoparathyroidism, unspecified
0.000 0.836 0.164
E24.9 Cushing's syndrome, unspecified
0.000 0.836 0.164
E55 Vitamin D deficiency
0.000 0.839 0.160
E31 Polyglandular dysfunction
0.000 0.841 0.159
E07.9 Disorder of thyroid, unspecified
0.000 0.842 0.158
E06.5 Other chronic thyroiditis
0.000 0.843 0.157
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.845 0.155
E23.1 Drug-induced hypopituitarism
0.000 0.845 0.155
E28 Ovarian dysfunction
0.000 0.845 0.155
E56.1 Deficiency of vitamin K
0.000 0.845 0.154
E51.9 Thiamine deficiency, unspecified
0.000 0.846 0.154
E51.8 Other manifestations of thiamine deficiency
0.000 0.846 0.154
E51.1 Beriberi
0.000 0.846 0.154
E22 Hyperfunction of pituitary gland
0.000 0.847 0.153
E11.3 With ophthalmic complications
0.000 0.848 0.152
E61 Deficiency of other nutrient elements
0.000 0.851 0.149
E24.2 Drug-induced Cushing's syndrome
0.000 0.851 0.149
E53.9 Vitamin B deficiency, unspecified
0.000 0.852 0.148
E56.9 Vitamin deficiency, unspecified
0.000 0.853 0.147
E56.8 Deficiency of other vitamins
0.000 0.853 0.147
E56.0 Deficiency of vitamin E
0.000 0.853 0.147
E26 Hyperaldosteronism
0.000 0.854 0.146
E67 Other hyperalimentation
0.000 0.856 0.144
E68 Sequelae of hyperalimentation
0.000 0.856 0.144
E23.7 Disorder of pituitary gland, unspecified
0.000 0.857 0.143
E24.8 Other Cushing's syndrome
0.000 0.857 0.143
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.857 0.143
E24.3 Ectopic ACTH syndrome
0.000 0.857 0.143
E24.1 Nelson's syndrome
0.000 0.857 0.143
E24.0 Pituitary-dependent Cushing's disease
0.000 0.857 0.143
E83.3 Disorders of phosphorus metabolism
0.142 0.858 0.000
E20.8 Other hypoparathyroidism
0.000 0.859 0.141
E20.1 Pseudohypoparathyroidism
0.000 0.859 0.141
E20.0 Idiopathic hypoparathyroidism
0.000 0.859 0.141
E04.0 Non-toxic diffuse goitre
0.001 0.859 0.141
E50.9 Vitamin A deficiency, unspecified
0.000 0.859 0.141
E50.8 Other manifestations of vitamin A deficiency
0.000 0.859 0.141
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.859 0.141
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.859 0.141
E50.5 Vitamin A deficiency with night blindness
0.000 0.859 0.141
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.859 0.141
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.859 0.141
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.859 0.141
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.859 0.141
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.859 0.141
E63.9 Nutritional deficiency, unspecified
0.000 0.859 0.141
E63.8 Other specified nutritional deficiencies
0.000 0.859 0.141
E63.1 Imbalance of constituents of food intake
0.000 0.859 0.141
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.859 0.141
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.859 0.141
E64.8 Sequelae of other nutritional deficiencies
0.000 0.859 0.141
E64.3 Sequelae of rickets
0.000 0.859 0.141
E64.2 Sequelae of vitamin C deficiency
0.000 0.859 0.141
E64.1 Sequelae of vitamin A deficiency
0.000 0.859 0.141
E64.0 Sequelae of protein-energy malnutrition
0.000 0.859 0.141
E83.9 Disorder of mineral metabolism, unspecified
0.135 0.865 0.000
E83.8 Other disorders of mineral metabolism
0.135 0.865 0.000
E83.2 Disorders of zinc metabolism
0.135 0.865 0.000
E83.0 Disorders of copper metabolism
0.135 0.865 0.000
E23.6 Other disorders of pituitary gland
0.000 0.866 0.134
E34 Other endocrine disorders
0.000 0.866 0.134
E29.1 Testicular hypofunction
0.000 0.873 0.127
E29.9 Testicular dysfunction, unspecified
0.000 0.874 0.126
E29.8 Other testicular dysfunction
0.000 0.874 0.126
E29.0 Testicular hyperfunction
0.000 0.874 0.126
E25.9 Adrenogenital disorder, unspecified
0.000 0.875 0.125
E25.8 Other adrenogenital disorders
0.000 0.875 0.125
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.875 0.125
E30.9 Disorder of puberty, unspecified
0.000 0.875 0.125
E30.8 Other disorders of puberty
0.000 0.875 0.125
E30.1 Precocious puberty
0.000 0.875 0.125
E30.0 Delayed puberty
0.000 0.875 0.125
E32.9 Disease of thymus, unspecified
0.000 0.875 0.125
E32.8 Other diseases of thymus
0.000 0.875 0.125
E32.1 Abscess of thymus
0.000 0.875 0.125
E32.0 Persistent hyperplasia of thymus
0.000 0.875 0.125
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.875 0.125
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.875 0.125
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.875 0.125
E53.1 Pyridoxine deficiency
0.000 0.876 0.124
E53.0 Riboflavin deficiency
0.000 0.876 0.124
E28.3 Primary ovarian failure
0.000 0.879 0.121
E22.0 Acromegaly and pituitary gigantism
0.000 0.884 0.116
E55.0 Rickets, active
0.000 0.885 0.115
E31.9 Polyglandular dysfunction, unspecified
0.000 0.886 0.114
E31.8 Other polyglandular dysfunction
0.000 0.886 0.114
E31.1 Polyglandular hyperfunction
0.000 0.886 0.114
E65 Localised adiposity
0.000 0.888 0.111
E28.9 Ovarian dysfunction, unspecified
0.000 0.889 0.111
E28.8 Other ovarian dysfunction
0.000 0.889 0.111
E28.1 Androgen excess
0.000 0.889 0.111
E28.0 Oestrogen excess
0.000 0.889 0.111
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.890 0.110
E22.8 Other hyperfunction of pituitary gland
0.000 0.890 0.110
E27 Other disorders of adrenal gland
0.000 0.891 0.109
E61.9 Deficiency of nutrient element, unspecified
0.000 0.893 0.107
E61.8 Deficiency of other specified nutrient elements
0.000 0.893 0.107
E61.7 Deficiency of multiple nutrient elements
0.000 0.893 0.107
E61.6 Vanadium deficiency
0.000 0.893 0.107
E61.5 Molybdenum deficiency
0.000 0.893 0.107
E61.4 Chromium deficiency
0.000 0.893 0.107
E61.3 Manganese deficiency
0.000 0.893 0.107
E61.0 Copper deficiency
0.000 0.893 0.107
E83.4 Disorders of magnesium metabolism
0.105 0.895 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.895 0.105
E26.8 Other hyperaldosteronism
0.000 0.895 0.105
E26.1 Secondary hyperaldosteronism
0.000 0.895 0.105
E67.8 Other specified hyperalimentation
0.000 0.896 0.103
E67.3 Hypervitaminosis D
0.000 0.896 0.103
E67.2 Megavitamin-B6 syndrome
0.000 0.896 0.103
E67.1 Hypercarotenaemia
0.000 0.896 0.103
E67.0 Hypervitaminosis A
0.000 0.896 0.103
E22.1 Hyperprolactinaemia
0.000 0.898 0.102
E31.0 Autoimmune polyglandular failure
0.000 0.901 0.098
E61.2 Magnesium deficiency
0.000 0.902 0.098
E06.3 Autoimmune thyroiditis
0.000 0.902 0.098
E34.5 Androgen resistance syndrome
0.000 0.904 0.096
E34.4 Constitutional tall stature
0.000 0.904 0.096
E34.3 Short stature, not elsewhere classified
0.000 0.904 0.096
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.904 0.096
E34.1 Other hypersecretion of intestinal hormones
0.000 0.904 0.096
E34.8 Other specified endocrine disorders
0.000 0.907 0.093
E34.9 Endocrine disorder, unspecified
0.000 0.910 0.090
E27.1 Primary adrenocortical insufficiency
0.000 0.910 0.090
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.912 0.088
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.919 0.081
E55.9 Vitamin D deficiency, unspecified
0.000 0.921 0.079
E27.5 Adrenomedullary hyperfunction
0.000 0.922 0.078
E27.0 Other adrenocortical overactivity
0.000 0.922 0.078
E26.0 Primary hyperaldosteronism
0.000 0.924 0.076
E27.8 Other specified disorders of adrenal gland
0.000 0.925 0.075
E61.1 Iron deficiency
0.000 0.925 0.075
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.927 0.073
E28.2 Polycystic ovarian syndrome
0.000 0.928 0.072
E34.0 Carcinoid syndrome
0.000 0.929 0.071
E27.9 Disorder of adrenal gland, unspecified
0.000 0.932 0.068
E83.5 Disorders of calcium metabolism
0.064 0.936 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.940 0.060
E21.4 Other specified disorders of parathyroid gland
0.000 0.941 0.058
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.942 0.058
E27.2 Addisonian crisis
0.000 0.944 0.056
H54.0 Blindness, both eyes
0.000 0.944 0.056
E21.2 Other hyperparathyroidism
0.000 0.944 0.055
E21.3 Hyperparathyroidism, unspecified
0.000 0.945 0.055
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.951 0.049
H54 Blindness and low vision
0.000 0.952 0.048
H54.9 Unspecified visual impairment (binocular)
0.000 0.957 0.043
E11.9 Without complications
0.000 0.958 0.042
H54.6 Unqualified visual loss, one eye
0.000 0.958 0.042
E04.1 Non-toxic single thyroid nodule
0.001 0.959 0.040
H54.7 Unspecified visual loss
0.000 0.961 0.039
H54.5 Low vision, one eye
0.000 0.963 0.037
K50-K52 Noninfective enteritis and colitis
0.037 0.963 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.964 0.036
H54.3 Unqualified visual loss, both eyes
0.000 0.965 0.034
H54.4 Blindness, one eye
0.000 0.966 0.034
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
H54.1 Blindness, one eye, low vision, other eye
0.000 0.969 0.031
K90-K93 Other diseases of the digestive system
0.001 0.969 0.030
H54.2 Low vision, both eyes
0.000 0.971 0.029
E66 Obesity
0.000 0.973 0.027
C43.5 Malignant melanoma of trunk
0.000 0.975 0.025
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.977 0.022
K50 Crohn's disease [regional enteritis]
0.022 0.978 0.000
E04.2 Non-toxic multinodular goitre
0.001 0.980 0.020
E66.1 Drug-induced obesity
0.000 0.980 0.020
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.018 0.982 0.000
K50.9 Crohn's disease, unspecified
0.018 0.982 0.000
E66.0 Obesity due to excess calories
0.000 0.983 0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.984 0.016
K93.1 Megacolon in Chagas' disease
0.001 0.984 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.984 0.016
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.984 0.016
H53-H54 Visual disturbances and blindness
0.000 0.984 0.016
K50.0 Crohn's disease of small intestine
0.016 0.984 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.014 0.986 0.000
J38.7 Other diseases of larynx
0.014 0.986 0.000
J38.3 Other diseases of vocal cords
0.014 0.986 0.000
J38.2 Nodules of vocal cords
0.014 0.986 0.000
J38.4 Oedema of larynx
0.014 0.986 0.000
C43 Malignant melanoma of skin
0.000 0.986 0.014
K50.1 Crohn's disease of large intestine
0.013 0.987 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.987 0.013
E21.0 Primary hyperparathyroidism
0.000 0.987 0.012
A08 Viral and other specified intestinal infections
0.000 0.988 0.012
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.988 0.012
J38.5 Laryngeal spasm
0.012 0.988 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.988 0.012
K50.8 Other Crohn's disease
0.011 0.989 0.000
H53.2 Diplopia
0.000 0.989 0.011
Z99.1 Dependence on respirator
0.000 0.989 0.011
E66.8 Other obesity
0.000 0.989 0.011
C43.4 Malignant melanoma of scalp and neck
0.000 0.990 0.010
C43.8 Overlapping malignant melanoma of skin
0.000 0.990 0.010
C43.0 Malignant melanoma of lip
0.000 0.990 0.010
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.990 0.010
A08.3 Other viral enteritis
0.000 0.990 0.010
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.990 0.010
C43.9 Malignant melanoma of skin, unspecified
0.000 0.990 0.010
H53 Visual disturbances
0.000 0.990 0.010
A08.5 Other specified intestinal infections
0.000 0.991 0.009
A08.2 Adenoviral enteritis
0.000 0.991 0.009
A08.0 Rotaviral enteritis
0.000 0.991 0.009
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.991 0.009
J38.1 Polyp of vocal cord and larynx
0.009 0.991 0.000
H53.1 Subjective visual disturbances
0.000 0.991 0.009
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.992 0.008
J38.6 Stenosis of larynx
0.008 0.992 0.000
I83 Varicose veins of lower extremities
0.008 0.992 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.992 0.008
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.993 0.007
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.993 0.007
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.993 0.007
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
M25.76 Osteophyte (Lower leg)
0.000 0.993 0.007
H53.6 Night blindness
0.000 0.993 0.007
H53.5 Colour vision deficiencies
0.000 0.993 0.007
H53.3 Other disorders of binocular vision
0.000 0.993 0.007
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.993 0.007
V18.0 Driver injured in nontraffic accident
0.007 0.993 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.007 0.993 0.000
K92.1 Melaena
0.007 0.993 0.000
J38.0 Paralysis of vocal cords and larynx
0.007 0.993 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.993 0.006
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.993 0.006
Z99.8 Dependence on other enabling machines and devices
0.000 0.994 0.006
S64.0 Injury of ulnar nerve at wrist and hand level
0.006 0.994 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.994 0.006
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.994 0.006
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.000 0.994 0.006
K92.0 Haematemesis
0.006 0.994 0.000
K92 Other diseases of digestive system
0.005 0.994 0.001
N85.1 Endometrial adenomatous hyperplasia
0.000 0.994 0.006
K04.5 Chronic apical periodontitis
0.005 0.995 0.000
N18.5 Chronic kidney disease, stage 5
0.000 0.995 0.005
I83.1 Varicose veins of lower extremities with inflammation
0.005 0.995 0.000
J81 Pulmonary oedema
0.000 0.995 0.005
I83.0 Varicose veins of lower extremities with ulcer
0.005 0.995 0.000
H53.4 Visual field defects
0.000 0.995 0.005
Z99.2 Dependence on renal dialysis
0.000 0.995 0.005
J35.8 Other chronic diseases of tonsils and adenoids
0.005 0.995 0.000
X41.9 Unspecified place
0.005 0.995 0.000
K92.8 Other specified diseases of digestive system
0.004 0.995 0.000
N60.2 Fibroadenosis of breast
0.005 0.995 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.995 0.005
F45.8 Other somatoform disorders
0.000 0.995 0.005
M25.71 Osteophyte (Shoulder region)
0.000 0.995 0.005
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.995 0.005
Z99.4 Dependence on artificial heart
0.000 0.995 0.005
Z99.0 Dependence on aspirator
0.000 0.995 0.005
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.005 0.995 0.000
H53.0 Amblyopia ex anopsia
0.000 0.995 0.005
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.996 0.004
L53.9 Erythematous condition, unspecified
0.004 0.996 0.000
E70-E90 Metabolic disorders
0.001 0.996 0.003
O43.8 Other placental disorders
0.000 0.996 0.004
K14.8 Other diseases of tongue
0.000 0.996 0.004
D30.3 Bladder
0.004 0.996 0.000
S42.10 Fracture of scapula (closed)
0.000 0.996 0.004
E73 Lactose intolerance
0.001 0.996 0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.996 0.004
E79 Disorders of purine and pyrimidine metabolism
0.001 0.996 0.003
M25.7 Osteophyte
0.000 0.996 0.004
N18.0 End-stage renal disease
0.000 0.996 0.004
M79.0 Rheumatism, unspecified
0.000 0.997 0.003
Q23.1 Congenital insufficiency of aortic valve
0.003 0.997 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.997 0.003
N18 Chronic renal failure
0.000 0.997 0.003
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.001 0.997 0.002
E76 Disorders of glycosaminoglycan metabolism
0.001 0.997 0.002
E72 Other disorders of amino-acid metabolism
0.001 0.997 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.997 0.002
E70 Disorders of aromatic amino-acid metabolism
0.001 0.997 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.997 0.002
Q23 Congenital malformations of aortic and mitral valves
0.003 0.997 0.000
M79.08 Rheumatism, unspecified (Other)
0.000 0.997 0.003
E73.9 Lactose intolerance, unspecified
0.000 0.997 0.003
Q23.0 Congenital stenosis of aortic valve
0.003 0.997 0.000
E74 Other disorders of carbohydrate metabolism
0.001 0.997 0.003
S64 Injury of nerves at wrist and hand level
0.003 0.997 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.003 0.997 0.000
N34.2 Other urethritis
0.003 0.997 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.003 0.997 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.997 0.002
E84 Cystic fibrosis
0.001 0.997 0.002
J35.2 Hypertrophy of adenoids
0.003 0.997 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.003 0.997 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.000 0.997 0.003
K52 Other non-infective gastro-enteritis and colitis
0.003 0.997 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.003 0.997 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
M62.82 Other specified disorders of muscle (Upper arm)
0.000 0.997 0.003
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.997 0.003
K92.2 Gastro-intestinal haemorrhage, unspecified
0.003 0.997 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.003 0.997 0.000
S64.1 Injury of median nerve at wrist and hand level
0.003 0.997 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.003 0.997 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.003 0.997 0.000
D47.4 Osteomyelofibrosis
0.000 0.997 0.003
M25.79 Osteophyte (Site unspecified)
0.000 0.997 0.003
C82.3 Follicular lymphoma grade IIIa
0.003 0.997 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
E73.8 Other lactose intolerance
0.001 0.997 0.002
E73.1 Secondary lactase deficiency
0.001 0.997 0.002
E73.0 Congenital lactase deficiency
0.001 0.997 0.002
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.997 0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.997 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.997 0.002
E79.1 Lesch-Nyhan syndrome
0.001 0.997 0.002
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified
0.003 0.997 0.000
M25.70 Osteophyte (Multiple sites)
0.000 0.997 0.003
I84.4 External haemorrhoids with other complications
0.003 0.997 0.000
M62.8 Other specified disorders of muscle
0.000 0.997 0.003
L43.9 Lichen planus, unspecified
0.000 0.997 0.003
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.997 0.003
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.997 0.003
M79.04 Rheumatism, unspecified (Hand)
0.000 0.997 0.003
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.997 0.003
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.997 0.003
N00-N08 Glomerular diseases
0.000 0.997 0.003
E85 Amyloidosis
0.001 0.997 0.002
V18.5 Passenger injured in traffic accident
0.003 0.997 0.000
M25.72 Osteophyte (Upper arm)
0.000 0.997 0.003
L53 Other erythematous conditions
0.003 0.997 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.003 0.997 0.000
C82.0 Small cleaved cell, follicular
0.003 0.997 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.997 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.997 0.002
E70.3 Albinism
0.001 0.997 0.002
E70.2 Disorders of tyrosine metabolism
0.001 0.997 0.002
E70.1 Other hyperphenylalaninaemias
0.001 0.997 0.002
E70.0 Classical phenylketonuria
0.001 0.997 0.002
E71.3 Disorders of fatty-acid metabolism
0.001 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.997 0.002
E71.0 Maple-syrup-urine disease
0.001 0.997 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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