TreeWAS – Variant ID: rs1375785

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.291	0.709	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.288	0.712	0.000
C85.1 B-cell lymphoma, unspecified	0.278	0.722	0.000
C91 Lymphoid leukaemia	0.277	0.723	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.275	0.725	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.271	0.729	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.268	0.732	0.000
C83.3 Large cell (diffuse)	0.260	0.740	0.000
C91.1 Chronic lymphocytic leukaemia	0.259	0.741	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.255	0.745	0.000
C81 Hodgkin's disease	0.239	0.761	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.238	0.762	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.235	0.765	0.000
C91.4 Hairy-cell leukaemia	0.227	0.773	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.226	0.774	0.000
C86 Other specified types of T/NK-cell lymphoma	0.220	0.780	0.000
C92 Myeloid leukaemia	0.219	0.781	0.000
C91.5 Adult T-cell leukaemia	0.219	0.781	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.217	0.783	0.000
C82.0 Small cleaved cell, follicular	0.217	0.783	0.000
C93 Monocytic leukaemia	0.212	0.788	0.000
C85.0 Lymphosarcoma	0.211	0.789	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.207	0.793	0.000
C91.0 Acute lymphoblastic leukaemia	0.204	0.796	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.203	0.797	0.000
C82.2 Large cell, follicular	0.202	0.798	0.000
C83.7 Burkitt's tumour	0.200	0.800	0.000
C95 Leukaemia of unspecified cell type	0.199	0.801	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.199	0.801	0.000
C91.7 Other lymphoid leukaemia	0.199	0.801	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.199	0.801	0.000
C91.3 Prolymphocytic leukaemia	0.199	0.801	0.000
C91.2 Subacute lymphocytic leukaemia	0.199	0.801	0.000
C82.3 Follicular lymphoma grade IIIa	0.198	0.802	0.000
C83.6 Undifferentiated (diffuse)	0.197	0.803	0.000
C83.4 Immunoblastic (diffuse)	0.197	0.803	0.000
C91.9 Lymphoid leukaemia, unspecified	0.196	0.804	0.000
C88 Malignant immunoproliferative diseases	0.195	0.805	0.000
C81.2 Mixed cellularity	0.194	0.806	0.000
C82.6 Cutaneous follicle centre lymphoma	0.194	0.806	0.000
C82.5 Diffuse follicle centre lymphoma	0.194	0.806	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.194	0.806	0.000
C81.9 Hodgkin's disease, unspecified	0.192	0.808	0.000
C83.2 Mixed small and large cell (diffuse)	0.191	0.809	0.000
C83.0 Small cell (diffuse)	0.190	0.809	0.000
C83.5 Lymphoblastic (diffuse)	0.185	0.815	0.000
C94 Other leukaemias of specified cell type	0.185	0.815	0.000
C82.4 Follicular lymphoma grade IIIb	0.184	0.815	0.000
C81.7 Other Hodgkin's disease	0.175	0.825	0.000
C81.0 Lymphocytic predominance	0.175	0.825	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.171	0.828	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.171	0.829	0.000
C81.3 Lymphocytic depletion	0.171	0.829	0.000
C92.1 Chronic myeloid leukaemia	0.171	0.829	0.000
C92.9 Myeloid leukaemia, unspecified	0.169	0.831	0.000
C92.4 Acute promyelocytic leukaemia	0.168	0.832	0.000
C83.1 Small cleaved cell (diffuse)	0.166	0.833	0.000
C92.2 Subacute myeloid leukaemia	0.165	0.835	0.000
C92.5 Acute myelomonocytic leukaemia	0.163	0.837	0.000
C92.7 Other myeloid leukaemia	0.160	0.840	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.158	0.842	0.000
C86.4 Blastic NK-cell lymphoma	0.158	0.842	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.158	0.842	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.158	0.842	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.158	0.842	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.158	0.842	0.000
C93.1 Chronic monocytic leukaemia	0.158	0.842	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.157	0.843	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.157	0.843	0.000
C92.3 Myeloid sarcoma	0.157	0.843	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.157	0.843	0.000
C93.9 Monocytic leukaemia, unspecified	0.152	0.848	0.000
C93.7 Other monocytic leukaemia	0.152	0.848	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.152	0.848	0.000
C93.2 Subacute monocytic leukaemia	0.152	0.848	0.000
C93.0 Acute monocytic leukaemia	0.152	0.848	0.000
C95.9 Leukaemia, unspecified	0.151	0.849	0.000
C81.1 Nodular sclerosis	0.151	0.849	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.148	0.851	0.000
C96.8 Histiocytic sarcoma	0.148	0.851	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.148	0.851	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.148	0.851	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.148	0.851	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.148	0.851	0.000
C96.3 True histiocytic lymphoma	0.148	0.851	0.000
C96.2 Malignant mast cell tumour	0.148	0.851	0.000
C96.1 Malignant histiocytosis	0.148	0.851	0.000
C96.0 Letterer-Siwe disease	0.148	0.851	0.000
C95.7 Other leukaemia of unspecified cell type	0.143	0.857	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.143	0.857	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.141	0.859	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.140	0.860	0.000
C88.7 Other malignant immunoproliferative diseases	0.140	0.860	0.000
C88.3 Immunoproliferative small intestinal disease	0.140	0.860	0.000
C88.2 Gamma heavy chain disease	0.140	0.860	0.000
C88.1 Alpha heavy chain disease	0.140	0.860	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.139	0.861	0.000
C94.7 Other specified leukaemias	0.132	0.867	0.000
C94.5 Acute myelofibrosis	0.132	0.867	0.000
C94.3 Mast cell leukaemia	0.132	0.867	0.000
C94.2 Acute megakaryoblastic leukaemia	0.132	0.867	0.000
C94.1 Chronic erythraemia	0.132	0.867	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.132	0.867	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.130	0.870	0.000
C94.4 Acute panmyelosis	0.130	0.870	0.000
C95.0 Acute leukaemia of unspecified cell type	0.128	0.872	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.127	0.872	0.000
C84.5 Other and unspecified T-cell lymphomas	0.115	0.885	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.114	0.886	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.112	0.887	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.112	0.887	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.112	0.887	0.000
C84.3 Lymphoepithelioid lymphoma	0.112	0.887	0.000
C84.2 T-zone lymphoma	0.112	0.887	0.000
C84.1 Sezary's diease	0.112	0.887	0.000
C84.4 Peripheral T-cell lymphoma	0.108	0.892	0.000
C90.3 Solitary plasmacytoma	0.100	0.900	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.093	0.906	0.000
C84.0 Mycosis fungoides	0.093	0.907	0.000
C92.0 Acute myeloid leukaemia	0.089	0.911	0.000
C90.1 Plasma cell leukaemia	0.079	0.920	0.000
C90.2 Plasmacytoma, extramedullary	0.072	0.928	0.000
C90.0 Multiple myeloma	0.067	0.933	0.000
B37.8 Candidiasis of other sites	0.050	0.950	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.951	0.049
S82.80 Fractures of other parts of lower leg (closed)	0.043	0.957	0.000
S82.8 Fractures of other parts of lower leg	0.039	0.961	0.000
N13 Obstructive and reflux uropathy	0.000	0.962	0.038
S82 Fracture of lower leg, including ankle	0.037	0.963	0.000
S82.0 Fracture of patella	0.035	0.965	0.000
N13.4 Hydroureter	0.000	0.965	0.035
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.966	0.034
S82.00 Fracture of patella (closed)	0.034	0.966	0.000
S82.4 Fracture of fibula alone	0.034	0.966	0.000
S82.40 Fracture of fibula alone (closed)	0.032	0.968	0.000
B37 Candidiasis	0.031	0.969	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.969	0.031
S82.81 Fractures of other parts of lower leg (open)	0.030	0.970	0.000
S82.1 Fracture of upper end of tibia	0.029	0.971	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.971	0.029
S82.86 Maisonneuve's fracture	0.028	0.971	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.972	0.028
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.972	0.028
S82.9 Fracture of lower leg, part unspecified	0.027	0.973	0.000
S82.2 Fracture of shaft of tibia	0.027	0.973	0.000
S82.01 Fracture of patella (open)	0.027	0.973	0.000
S82.6 Fracture of lateral malleolus	0.027	0.973	0.000
N13.6 Pyonephrosis	0.000	0.973	0.027
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.975	0.025
S82.41 Fracture of fibula alone (open)	0.024	0.975	0.000
B37.9 Candidiasis, unspecified	0.024	0.975	0.000
S82.21 Fracture of shaft of tibia (open)	0.024	0.976	0.000
B37.7 Candidal septicaemia	0.024	0.976	0.000
B37.4 Candidiasis of other urogenital sites	0.024	0.976	0.000
B37.1 Pulmonary candidiasis	0.023	0.977	0.000
S80-S89 Injuries to the knee and lower leg	0.023	0.977	0.000
S82.7 Multiple fractures of lower leg	0.023	0.977	0.000
S83.2 Tear of meniscus, current	0.023	0.977	0.000
B37.3 Candidiasis of vulva and vagina	0.023	0.977	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.023	0.977	0.000
B37.6 Candidal endocarditis	0.022	0.978	0.000
B37.5 Candidal meningitis	0.022	0.978	0.000
S82.10 Fracture of upper end of tibia (closed)	0.022	0.978	0.000
S82.11 Fracture of upper end of tibia (open)	0.022	0.978	0.000
B37.2 Candidiasis of skin and nail	0.022	0.978	0.000
S82.3 Fracture of lower end of tibia	0.021	0.978	0.000
S82.5 Fracture of medial malleolus	0.020	0.980	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.020	0.980	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.020	0.980	0.000
S82.60 Fracture of lateral malleolus (closed)	0.020	0.980	0.000
S82.61 Fracture of lateral malleolus (open)	0.019	0.981	0.000
S81 Open wound of lower leg	0.019	0.981	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.018	0.982	0.000
S87 Crushing injury of lower leg	0.018	0.982	0.000
S82.31 Fracture of lower end of tibia (open)	0.018	0.982	0.000
S85 Injury of blood vessels at lower leg level	0.018	0.982	0.000
S83.7 Injury to multiple structures of knee	0.018	0.982	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.018	0.982	0.000
S84 Injury of nerves at lower leg level	0.017	0.983	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.017	0.983	0.000
S88 Traumatic amputation of lower leg	0.017	0.983	0.000
S82.71 Multiple fractures of lower leg (open)	0.017	0.983	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.017	0.983	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.017	0.983	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.017	0.983	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.983	0.017
S83.0 Dislocation of patella	0.016	0.984	0.000
S81.0 Open wound of knee	0.016	0.984	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.016	0.984	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.016	0.984	0.000
B37.0 Candidal stomatitis	0.016	0.984	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.016	0.984	0.000
T39.0 Salicylates	0.016	0.984	0.000
S81.8 Open wound of other parts of lower leg	0.015	0.985	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.015	0.985	0.000
T45.0 Antiallergic and antiemetic drugs	0.015	0.985	0.000
S83.3 Tear of articular cartilage of knee, current	0.015	0.985	0.000
S82.51 Fracture of medial malleolus (open)	0.015	0.985	0.000
B35-B49 Mycoses	0.015	0.985	0.000
S89 Other and unspecified injuries of lower leg	0.015	0.985	0.000
T40.2 Other opioids	0.015	0.985	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.015	0.985	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.014	0.986	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.014	0.986	0.000
S86 Injury of muscle and tendon at lower leg level	0.014	0.986	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.014	0.986	0.000
T36 Poisoning by systemic antibiotics	0.014	0.986	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.986	0.014
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.014	0.986	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.014	0.986	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.014	0.986	0.000
T45.2 Vitamins, not elsewhere classified	0.014	0.986	0.000
S83.1 Dislocation of knee	0.013	0.986	0.000
S82.70 Multiple fractures of lower leg (closed)	0.013	0.986	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.014	0.986	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.013	0.986	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.013	0.987	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.013	0.987	0.000
S87.0 Crushing injury of knee	0.013	0.987	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.013	0.987	0.000
M65.8 Other synovitis and tenosynovitis	0.000	0.987	0.013
T46.5 Other antihypertensive drugs, not elsewhere classified	0.013	0.987	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.013	0.987	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.013	0.987	0.000
S85.8 Injury of other blood vessels at lower leg level	0.013	0.987	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.013	0.987	0.000
S85.5 Injury of popliteal vein	0.013	0.987	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.013	0.987	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.013	0.987	0.000
S85.2 Injury of peroneal artery	0.013	0.987	0.000
S85.0 Injury of popliteal artery	0.013	0.987	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.013	0.987	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.013	0.987	0.000
S84.8 Injury of other nerves at lower leg level	0.013	0.987	0.000
S84.7 Injury of multiple nerves at lower leg level	0.013	0.987	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.013	0.987	0.000
S84.0 Injury of tibial nerve at lower leg level	0.013	0.987	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.013	0.987	0.000
K76.8 Other specified diseases of liver	0.013	0.987	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.012	0.987	0.000
T40.3 Methadone	0.012	0.987	0.000
T46.1 Calcium-channel blockers	0.012	0.987	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.012	0.987	0.000
T45.8 Other primarily systemic and haematological agents	0.012	0.987	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.012	0.987	0.000
T45.6 Fibrinolysis-affecting drugs	0.012	0.987	0.000
T45.4 Iron and its compounds	0.012	0.987	0.000
T45.3 Enzymes, not elsewhere classified	0.012	0.987	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.012	0.987	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.012	0.987	0.000
S88.0 Traumatic amputation at knee level	0.012	0.987	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.988	0.012
T45.5 Anticoagulants	0.012	0.988	0.000
T40.4 Other synthetic narcotics	0.012	0.988	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.012	0.988	0.000
T46.7 Peripheral vasodilators	0.012	0.988	0.000
S81.7 Multiple open wounds of lower leg	0.012	0.988	0.000
B35 Dermatophytosis	0.012	0.988	0.000
T47.0 Histamine H(2)-receptor antagonists	0.012	0.988	0.000
T39.4 Antirheumatics, not elsewhere classified	0.012	0.988	0.000
T39.2 Pyrazolone derivatives	0.012	0.988	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.012	0.988	0.000
T40.6 Other and unspecified narcotics	0.012	0.988	0.000
M65 Synovitis and tenosynovitis	0.000	0.988	0.012
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.012	0.988	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.012	0.988	0.000
T40.8 Lysergide [LSD]	0.012	0.988	0.000
T40.7 Cannabis (derivatives)	0.012	0.988	0.000
T40.0 Opium	0.012	0.988	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.012	0.988	0.000
K76.6 Portal hypertension	0.012	0.988	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
T42.4 Benzodiazepines	0.012	0.988	0.000
T40.5 Cocaine	0.012	0.988	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.012	0.988	0.000
T47.2 Stimulant laxatives	0.012	0.988	0.000
T47.4 Other laxatives	0.011	0.988	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.011	0.988	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.011	0.988	0.000
T47.7 Emetics	0.011	0.988	0.000
T47.5 Digestants	0.011	0.988	0.000
T47.3 Saline and osmotic laxatives	0.011	0.988	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
B35.3 Tinea pedis	0.012	0.988	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.011	0.988	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.011	0.988	0.000
T47.6 Antidiarrhoeal drugs	0.011	0.989	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.989	0.011
T40.1 Heroin	0.011	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.011	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.011	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.011	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.011	0.989	0.000
T44.0 Anticholinesterase agents	0.011	0.989	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.011	0.989	0.000
S80 Superficial injury of lower leg	0.011	0.989	0.000
S81.9 Open wound of lower leg, part unspecified	0.011	0.989	0.000
T36.0 Penicillins	0.011	0.989	0.000
S82.20 Fracture of shaft of tibia (closed)	0.011	0.989	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.011	0.989	0.000
T42.1 Iminostilbenes	0.011	0.989	0.000
K76 Other diseases of liver	0.011	0.989	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.011	0.989	0.000
B49 Unspecified mycosis	0.011	0.989	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.989	0.000
B48 Other mycoses, not elsewhere classified	0.011	0.989	0.000
B46 Zygomycosis	0.011	0.989	0.000
B45 Cryptococcosis	0.011	0.989	0.000
B43 Chromomycosis and phaeomycotic abscess	0.011	0.989	0.000
B42 Sporotrichosis	0.011	0.989	0.000
B41 Paracoccidioidomycosis	0.011	0.989	0.000
B40 Blastomycosis	0.011	0.989	0.000
B39 Histoplasmosis	0.011	0.989	0.000
B38 Coccidioidomycosis	0.011	0.989	0.000
S89.7 Multiple injuries of lower leg	0.011	0.989	0.000
S89.1 Other specified injuries of lower leg	0.011	0.989	0.000
S89.0 Multiple injuries of lower leg	0.011	0.989	0.000
B47 Mycetoma	0.011	0.989	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.011	0.989	0.000
T42.2 Succinimides and oxazolidinediones	0.011	0.989	0.000
T42.3 Barbiturates	0.011	0.989	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.010	0.989	0.000
T36.8 Other systemic antibiotics	0.010	0.990	0.000
S86.0 Injury of Achilles tendon	0.010	0.990	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.010	0.990	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.010	0.990	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.990	0.010
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.990	0.010
T36.9 Systemic antibiotic, unspecified	0.010	0.990	0.000
T36.7 Antifungal antibiotics, systemically used	0.010	0.990	0.000
T36.6 Rifamycins	0.010	0.990	0.000
T36.5 Aminoglycosides	0.010	0.990	0.000
T36.2 Chloramphenicol group	0.010	0.990	0.000
W06.0 Home	0.000	0.990	0.010
T36.4 Tetracyclines	0.010	0.990	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.010	0.990	0.000
T48.4 Expectorants	0.010	0.990	0.000
T48.3 Antitussives	0.010	0.990	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.010	0.990	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.010	0.990	0.000
T48.0 Oxytocic drugs	0.010	0.990	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.010	0.990	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.010	0.990	0.000
T48.5 Anti-common-cold drugs	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
Z87.8 Personal history of other specified conditions	0.000	0.990	0.010
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.990	0.010
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.990	0.010
T49.9 Topical agent, unspecified	0.010	0.990	0.000
T49.8 Other topical agents	0.010	0.990	0.000
T49.7 Dental drugs, topically applied	0.010	0.990	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.010	0.990	0.000
T49.5 Ophthalmological drugs and preparations	0.010	0.990	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.010	0.990	0.000
T49.3 Emollients, demulcents and protectants	0.010	0.990	0.000
T49.2 Local astringents and local detergents	0.010	0.990	0.000
T49.1 Antipruritics	0.010	0.990	0.000
S89.9 Unspecified injury of lower leg	0.010	0.990	0.000
B44 Aspergillosis	0.010	0.990	0.000
T38.0 Glucocorticoids and synthetic analogues	0.010	0.990	0.000
T41.2 Other and unspecified general anaesthetics	0.010	0.990	0.000
T36.3 Macrolides	0.010	0.990	0.000
A49.0 Staphylococcal infection, unspecified	0.010	0.990	0.000
T41.5 Therapeutic gases	0.010	0.990	0.000
T41.4 Anaesthetic, unspecified	0.010	0.990	0.000
T41.3 Local anaesthetics	0.010	0.990	0.000
T41.1 Intravenous anaesthetics	0.010	0.990	0.000
T41.0 Inhaled anaesthetics	0.010	0.990	0.000
T38.9 Other and unspecified hormone antagonists	0.010	0.990	0.000
T38.7 Androgens and anabolic congeners	0.010	0.990	0.000
T38.4 Oral contraceptives	0.010	0.990	0.000
T38.2 Antithyroid drugs	0.010	0.990	0.000
T42.0 Hydantoin derivatives	0.010	0.990	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.990	0.010
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.990	0.010
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.990	0.010
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.990	0.010
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.990	0.010
K70 Alcoholic liver disease	0.010	0.990	0.000
S89.8 Other specified injuries of lower leg	0.009	0.990	0.000
M65.3 Trigger finger	0.000	0.990	0.009
T37.2 Antimalarials and drugs acting on other blood protozoa	0.009	0.990	0.000
T38.5 Other oestrogens and progestogens	0.009	0.990	0.000
B35.9 Dermatophytosis, unspecified	0.009	0.991	0.000
A49 Bacterial infection of unspecified site	0.009	0.991	0.000
M65.0 Abscess of tendon sheath	0.000	0.991	0.009
B35.6 Tinea cruris	0.009	0.991	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.991	0.000
T37.5 Antiviral drugs	0.009	0.991	0.000
T37.4 Anthelminthics	0.009	0.991	0.000
T37.3 Other antiprotozoal drugs	0.009	0.991	0.000
T37.1 Antimycobacterial drugs	0.009	0.991	0.000
T37.0 Sulphonamides	0.009	0.991	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.991	0.009
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.991	0.009
B36 Other superficial mycoses	0.009	0.991	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.991	0.009
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.009	0.991	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.991	0.009
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.991	0.009
T38.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
B35.8 Other dermatophytoses	0.009	0.991	0.000
B35.5 Tinea imbricata	0.009	0.991	0.000
B35.2 Tinea manuum	0.009	0.991	0.000
B35.0 Tinea barbae and tinea capitis	0.009	0.991	0.000
T50.8 Diagnostic agents	0.009	0.991	0.000
K70.9 Alcoholic liver disease, unspecified	0.009	0.991	0.000
S82.50 Fracture of medial malleolus (closed)	0.008	0.991	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.991	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.991	0.009
M65.2 Calcific tendinitis	0.000	0.991	0.009
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.991	0.009
B35.4 Tinea corporis	0.008	0.991	0.000
M65.1 Other infective (teno)synovitis	0.000	0.991	0.008
T50.7 Analeptics and opioid receptor antagonists	0.008	0.991	0.000
T50.5 Appetite depressants	0.008	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.008	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.008	0.991	0.000
K76.1 Chronic passive congestion of liver	0.008	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.991	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.008	0.991	0.000
A46 Erysipelas	0.008	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.008	0.992	0.000
K70-K77 Diseases of liver	0.008	0.992	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.008	0.992	0.000
A40 Streptococcal septicaemia	0.008	0.992	0.000
A30-A49 Other bacterial diseases	0.008	0.992	0.000
K76.3 Infarction of liver	0.008	0.992	0.000
K70.4 Alcoholic hepatic failure	0.008	0.992	0.000
B44.9 Aspergillosis, unspecified	0.008	0.992	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.992	0.008
K72 Hepatic failure, not elsewhere classified	0.008	0.992	0.000
K76.5 Hepatic veno-occlusive disease	0.008	0.992	0.000
K76.4 Peliosis hepatis	0.008	0.992	0.000
K76.2 Central haemorrhagic necrosis of liver	0.008	0.992	0.000
B38.9 Coccidioidomycosis, unspecified	0.008	0.992	0.000
B38.8 Other forms of coccidioidomycosis	0.008	0.992	0.000
B38.7 Disseminated coccidioidomycosis	0.008	0.992	0.000
B38.4 Coccidioidomycosis meningitis	0.008	0.992	0.000
B38.3 Cutaneous coccidioidomycosis	0.008	0.992	0.000
B38.2 Pulmonary coccidioidomycosis, unspecified	0.008	0.992	0.000
B38.1 Chronic pulmonary coccidioidomycosis	0.008	0.992	0.000
B38.0 Acute pulmonary coccidioidomycosis	0.008	0.992	0.000
B39.9 Histoplasmosis, unspecified	0.008	0.992	0.000
B39.5 Histoplasmosis duboisii	0.008	0.992	0.000
B39.4 Histoplasmosis capsulati, unspecified	0.008	0.992	0.000
B39.3 Disseminated histoplasmosis capsulati	0.008	0.992	0.000
B39.2 Pulmonary histoplasmosis capsulati, unspecified	0.008	0.992	0.000
B39.1 Chronic pulmonary histoplasmosis capsulati	0.008	0.992	0.000
B39.0 Acute pulmonary histoplasmosis capsulati	0.008	0.992	0.000
B40.9 Blastomycosis, unspecified	0.008	0.992	0.000
B40.8 Other forms of blastomycosis	0.008	0.992	0.000
B40.7 Disseminated blastomycosis	0.008	0.992	0.000
B40.3 Cutaneous blastomycosis	0.008	0.992	0.000
B40.2 Pulmonary blastomycosis, unspecified	0.008	0.992	0.000
B40.1 Chronic pulmonary blastomycosis	0.008	0.992	0.000
B40.0 Acute pulmonary blastomycosis	0.008	0.992	0.000
B41.9 Paracoccidioidomycosis, unspecified	0.008	0.992	0.000
B41.8 Other forms of paracoccidioidomycosis	0.008	0.992	0.000
B41.7 Disseminated paracoccidioidomycosis	0.008	0.992	0.000
B41.0 Pulmonary paracoccidioidomycosis	0.008	0.992	0.000
B42.9 Sporotrichosis, unspecified	0.008	0.992	0.000
B42.8 Other forms of sporotrichosis	0.008	0.992	0.000
B42.7 Disseminated sporotrichosis	0.008	0.992	0.000
B42.1 Lymphocutaneous sporotrichosis	0.008	0.992	0.000
B42.0 Pulmonary sporotrichosis	0.008	0.992	0.000
B43.9 Chromomycosis, unspecified	0.008	0.992	0.000
B43.8 Other forms of chromomycosis	0.008	0.992	0.000
B43.2 Subcutaneous phaeomycotic abscess and cyst	0.008	0.992	0.000
B43.1 Phaeomycotic brain abscess	0.008	0.992	0.000
B43.0 Cutaneous chromomycosis	0.008	0.992	0.000
B45.9 Cryptococcosis, unspecified	0.008	0.992	0.000
B45.8 Other forms of cryptococcosis	0.008	0.992	0.000
B45.7 Disseminated cryptococcosis	0.008	0.992	0.000
B45.3 Osseous cryptococcosis	0.008	0.992	0.000
B45.2 Cutaneous cryptococcosis	0.008	0.992	0.000
B45.1 Cerebral cryptococcosis	0.008	0.992	0.000
B45.0 Pulmonary cryptococcosis	0.008	0.992	0.000
B46.9 Zygomycosis, unspecified	0.008	0.992	0.000
B46.8 Other zygomycoses	0.008	0.992	0.000
B46.5 Mucormycosis, unspecified	0.008	0.992	0.000
B46.4 Disseminated mucormycosis	0.008	0.992	0.000
B46.3 Cutaneous mucormycosis	0.008	0.992	0.000
B46.2 Gastro-intestinal mucormycosis	0.008	0.992	0.000
B46.1 Rhinocerebral mucormycosis	0.008	0.992	0.000
B46.0 Pulmonary mucormycosis	0.008	0.992	0.000
B48.8 Other specified mycoses	0.008	0.992	0.000
B48.7 Opportunistic mycoses	0.008	0.992	0.000
B48.4 Penicillosis	0.008	0.992	0.000
B48.3 Geotrichosis	0.008	0.992	0.000
B48.2 Allescheriasis	0.008	0.992	0.000
B48.1 Rhinosporidiosis	0.008	0.992	0.000
B48.0 Lobomycosis	0.008	0.992	0.000
K70.1 Alcoholic hepatitis	0.008	0.992	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.008	0.992	0.000
B47.1 Actinomycetoma	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations