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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138355804
log Bayes Factor = 3.1184
Chromosome 4   position 30,402,249  (GRCh37) Explore rs138355804 on Ensembl!
Variant rs138355804 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.984 0.016 0.000
M15-M19 Arthrosis
0.972 0.028 0.000
Chapter I Certain infectious and parasitic diseases
0.964 0.036 0.000
M25 Other joint disorders, not elsewhere classified
0.958 0.042 0.000
H30-H36 Disorders of choroid and retina
0.944 0.056 0.000
M50-M54 Other dorsopathies
0.931 0.069 0.000
M20 Acquired deformities of fingers and toes
0.915 0.085 0.000
M19 Other arthrosis
0.908 0.092 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.903 0.097 0.000
Chapter V Mental and behavioural disorders
0.902 0.098 0.000
M25.5 Pain in joint
0.900 0.100 0.000
Chapter VI Diseases of the nervous system
0.894 0.106 0.000
M23 Internal derangement of knee
0.883 0.117 0.000
H33 Retinal detachments and breaks
0.878 0.122 0.000
A00-A09 Intestinal infectious diseases
0.870 0.130 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.866 0.134 0.000
M54 Dorsalgia
0.858 0.142 0.000
Chapter XXI Factors influencing health status and contact with health services
0.857 0.143 0.000
G40-G47 Episodic and paroxysmal disorders
0.844 0.156 0.000
M19.9 Arthrosis, unspecified
0.838 0.162 0.000
B95-B98 Bacterial, viral and other infectious agents
0.837 0.163 0.000
H43-H45 Disorders of vitreous body and globe
0.837 0.163 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.835 0.165 0.000
H40-H42 Glaucoma
0.833 0.167 0.000
M17 Gonarthrosis [arthrosis of knee]
0.831 0.169 0.000
Chapter XIV Diseases of the genitourinary system
0.827 0.173 0.000
G47 Sleep disorders
0.824 0.176 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.822 0.178 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.818 0.182 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.816 0.184 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.814 0.186 0.000
H35 Other retinal disorders
0.813 0.187 0.000
M20.5 Other deformities of toe(s) (acquired)
0.812 0.188 0.000
G47.3 Sleep apnoea
0.808 0.192 0.000
M05-M14 Inflammatory polyarthropathies
0.804 0.196 0.000
H33.0 Retinal detachment with retinal break
0.803 0.197 0.000
M25.7 Osteophyte
0.800 0.200 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.797 0.203 0.000
S60-S69 Injuries to the wrist and hand
0.797 0.203 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.791 0.209 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.789 0.211 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.786 0.214 0.000
M20.2 Hallux rigidus
0.785 0.215 0.000
M40-M43 Deforming dorsopathies
0.783 0.217 0.000
N84 Polyp of female genital tract
0.782 0.218 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.781 0.219 0.000
M50 Cervical disk disorders
0.773 0.227 0.000
M17.9 Gonarthrosis, unspecified
0.772 0.228 0.000
M45-M49 Spondylopathies
0.766 0.234 0.000
A30-A49 Other bacterial diseases
0.764 0.235 0.000
M16 Coxarthrosis [arthrosis of hip]
0.762 0.238 0.000
M23.3 Other meniscus derangements
0.761 0.239 0.000
M25.56 Pain in joint (Lower leg)
0.761 0.239 0.000
M18 Arthrosis of first carpometacarpal joint
0.761 0.239 0.000
M25.4 Effusion of joint
0.755 0.245 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.754 0.246 0.000
B25-B34 Other viral diseases
0.751 0.249 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.751 0.249 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.751 0.249 0.000
Chapter VIII Diseases of the ear and mastoid process
0.743 0.257 0.000
N84.0 Polyp of corpus uteri
0.741 0.259 0.000
M19.0 Primary arthrosis of other joints
0.740 0.260 0.000
M65-M68 Disorders of synovium and tendon
0.739 0.261 0.000
Z12 Special screening examination for neoplasms
0.731 0.269 0.000
H43 Disorders of vitreous body
0.731 0.269 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.271 0.000
M54.5 Low back pain
0.728 0.272 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.725 0.275 0.000
H33.3 Retinal breaks without detachment
0.725 0.275 0.000
H40 Glaucoma
0.725 0.275 0.000
H53-H54 Visual disturbances and blindness
0.724 0.276 0.000
M20.4 Other hammer toe(s) (acquired)
0.722 0.278 0.000
L40-L45 Papulosquamous disorders
0.721 0.279 0.000
H25-H28 Disorders of lens
0.719 0.281 0.000
F99-F99 Unspecified mental disorder
0.719 0.281 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.719 0.281 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.716 0.283 0.000
S61 Open wound of wrist and hand
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M86-M90 Other osteopathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
N95 Menopausal and other perimenopausal disorders
0.715 0.285 0.000
M24 Other specific joint derangements
0.712 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M31 Other necrotising vasculopathies
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
M22 Disorders of patella
0.712 0.288 0.000
M21 Other acquired deformities of limbs
0.712 0.288 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.710 0.290 0.000
H34 Retinal vascular occlusions
0.708 0.292 0.000
M80-M85 Disorders of bone density and structure
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.705 0.294 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.705 0.294 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.705 0.294 0.000
H10-H13 Disorders of conjunctiva
0.705 0.294 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.703 0.296 0.000
Chapter XX External causes of morbidity and mortality
0.700 0.299 0.000
M54.2 Cervicalgia
0.698 0.302 0.000
E10-E14 Diabetes mellitus
0.698 0.302 0.000
O60-O75 Complications of labour and delivery
0.697 0.303 0.000
M15 Polyarthrosis
0.697 0.303 0.000
M25.57 Pain in joint (Ankle and foot)
0.696 0.304 0.000
M54.3 Sciatica
0.693 0.307 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.692 0.308 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.692 0.308 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.691 0.309 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.691 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
A75-A79 Rickettsioses
0.691 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.309 0.000
A65-A69 Other spirochaetal diseases
0.691 0.309 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.691 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.309 0.000
A15-A19 Tuberculosis
0.691 0.309 0.000
B35-B49 Mycoses
0.690 0.310 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.690 0.310 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.689 0.311 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.688 0.312 0.000
M25.9 Joint disorder, unspecified
0.686 0.313 0.000
M25.8 Other specified joint disorders
0.686 0.313 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.686 0.313 0.000
M25.3 Other instability of joint
0.686 0.313 0.000
M25.2 Flail joint
0.686 0.313 0.000
M25.1 Fistula of joint
0.686 0.313 0.000
M25.0 Haemarthrosis
0.686 0.313 0.000
Chapter II Neoplasms
0.686 0.314 0.000
H35.4 Peripheral retinal degeneration
0.686 0.314 0.000
M23.8 Other internal derangements of knee
0.685 0.315 0.000
Z48 Other surgical follow-up care
0.680 0.319 0.000
M16.9 Coxarthrosis, unspecified
0.679 0.321 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.679 0.321 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.679 0.321 0.000
Z47 Other orthopaedic follow-up care
0.679 0.321 0.000
H35.8 Other specified retinal disorders
0.678 0.322 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.677 0.323 0.000
H31 Other disorders of choroid
0.677 0.323 0.000
H30 Chorioretinal inflammation
0.677 0.323 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.676 0.324 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.674 0.326 0.000
H36 Retinal disorders in diseases classified elsewhere
0.672 0.328 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.670 0.330 0.000
M53 Other dorsopathies, not elsewhere classified
0.667 0.332 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.667 0.333 0.000
Z53.9 Procedure not carried out, unspecified reason
0.665 0.335 0.000
S20-S29 Injuries to the thorax
0.663 0.337 0.000
S40-S49 Injuries to the shoulder and upper arm
0.661 0.339 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.661 0.339 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.660 0.340 0.000
N84.1 Polyp of cervix uteri
0.660 0.340 0.000
G20-G26 Extrapyramidal and movement disorders
0.656 0.343 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.656 0.344 0.000
M20.3 Other deformity of hallux (acquired)
0.656 0.344 0.000
M20.0 Deformity of finger(s)
0.656 0.344 0.000
Z53.0 Procedure not carried out because of contraindication
0.655 0.345 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.654 0.346 0.000
N81 Female genital prolapse
0.653 0.346 0.000
H40.9 Glaucoma, unspecified
0.652 0.348 0.000
M19.8 Other specified arthrosis
0.651 0.349 0.000
M19.2 Other secondary arthrosis
0.651 0.349 0.000
M19.1 Posttraumatic arthrosis of other joints
0.651 0.349 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.648 0.352 0.000
T79-T79 Certain early complications of trauma
0.648 0.352 0.000
T66-T78 Other and unspecified effects of external causes
0.648 0.352 0.000
T33-T35 Frostbite
0.648 0.352 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.648 0.352 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.648 0.352 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.352 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.648 0.352 0.000
T00-T07 Injuries involving multiple body regions
0.648 0.352 0.000
S90-S99 Injuries to the ankle and foot
0.648 0.352 0.000
S10-S19 Injuries to the neck
0.648 0.352 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.646 0.353 0.000
F80-F89 Disorders of psychological development
0.646 0.353 0.000
F70-F79 Mental retardation
0.646 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.646 0.353 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.646 0.353 0.000
M25.77 Osteophyte (Ankle and foot)
0.646 0.354 0.000
M25.59 Pain in joint (Site unspecified)
0.645 0.355 0.000
M25.58 Pain in joint (Other)
0.645 0.355 0.000
M25.54 Pain in joint (Hand)
0.645 0.355 0.000
M25.53 Pain in joint (Forearm)
0.645 0.355 0.000
M25.52 Pain in joint (Upper arm)
0.645 0.355 0.000
M25.50 Pain in joint (Multiple sites)
0.645 0.355 0.000
Z13 Special screening examination for other diseases and disorders
0.644 0.356 0.000
M54.9 Dorsalgia, unspecified
0.642 0.358 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.641 0.359 0.000
G70-G73 Diseases of myoneural junction and muscle
0.641 0.359 0.000
G30-G32 Other degenerative diseases of the nervous system
0.641 0.359 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.641 0.359 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.641 0.359 0.000
S80-S89 Injuries to the knee and lower leg
0.641 0.359 0.000
M06 Other rheumatoid arthritis
0.640 0.359 0.000
M35 Other systemic involvement of connective tissue
0.637 0.363 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.636 0.364 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.636 0.364 0.000
M51 Other intervertebral disk disorders
0.635 0.365 0.000
M25.76 Osteophyte (Lower leg)
0.634 0.366 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.634 0.366 0.000
G90-G99 Other disorders of the nervous system
0.633 0.367 0.000
M23.9 Internal derangement of knee, unspecified
0.633 0.367 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.633 0.367 0.000
M23.5 Chronic instability of knee
0.633 0.367 0.000
M23.4 Loose body in knee
0.633 0.367 0.000
M23.1 Discoid meniscus (congenital)
0.633 0.367 0.000
M23.0 Cystic meniscus
0.633 0.367 0.000
L50-L54 Urticaria and erythema
0.632 0.367 0.000
S70-S79 Injuries to the hip and thigh
0.631 0.369 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.631 0.369 0.000
N87 Dysplasia of cervix uteri
0.630 0.370 0.000
N89 Other noninflammatory disorders of vagina
0.630 0.370 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.630 0.370 0.000
H33.5 Other retinal detachments
0.630 0.370 0.000
H33.4 Traction detachment of retina
0.630 0.370 0.000
H33.1 Retinoschisis and retinal cysts
0.630 0.370 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.629 0.371 0.000
H33.2 Serous retinal detachment
0.629 0.371 0.000
H26 Other cataract
0.625 0.375 0.000
A08 Viral and other specified intestinal infections
0.624 0.376 0.000
A07 Other protozoal intestinal diseases
0.624 0.376 0.000
A06 Amoebiasis
0.624 0.376 0.000
A05 Other bacterial foodborne intoxications
0.624 0.376 0.000
A03 Shigellosis
0.624 0.376 0.000
A02 Other Salmonella infections
0.624 0.376 0.000
A01 Typhoid and paratyphoid fevers
0.624 0.376 0.000
A00 Cholera
0.624 0.376 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.623 0.377 0.000
Chapter X Diseases of the respiratory system
0.622 0.378 0.000
A41 Other septicaemia
0.621 0.378 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.621 0.379 0.000
G47.9 Sleep disorder, unspecified
0.621 0.379 0.000
L10-L14 Bullous disorders
0.621 0.379 0.000
E65-E68 Obesity and other hyperalimentation
0.621 0.379 0.000
M50.2 Other cervical disk displacement
0.621 0.379 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.620 0.380 0.000
N30-N39 Other diseases of urinary system
0.619 0.381 0.000
Z43 Attention to artificial openings
0.619 0.381 0.000
G40 Epilepsy
0.618 0.381 0.000
F17.1 Harmful use
0.617 0.383 0.000
M54.8 Other dorsalgia
0.615 0.384 0.000
M54.6 Pain in thoracic spine
0.615 0.384 0.000
M54.4 Lumbago with sciatica
0.615 0.384 0.000
M54.1 Radiculopathy
0.615 0.384 0.000
M54.0 Panniculitis affecting regions of neck and back
0.615 0.384 0.000
L40 Psoriasis
0.615 0.385 0.000
S61.0 Open wound of finger(s) without damage to nail
0.615 0.385 0.000
N93 Other abnormal uterine and vaginal bleeding
0.615 0.385 0.000
N95.2 Postmenopausal atrophic vaginitis
0.614 0.386 0.000
M10 Gout
0.613 0.387 0.000
F30-F39 Mood [affective] disorders
0.613 0.387 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.612 0.388 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.611 0.389 0.000
N25-N29 Other disorders of kidney and ureter
0.611 0.389 0.000
M50.3 Other cervical disk degeneration
0.610 0.390 0.000
M25.46 Effusion of joint (Lower leg)
0.609 0.391 0.000
M48 Other spondylopathies
0.609 0.391 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.609 0.391 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.608 0.392 0.000
F29 Unspecified nonorganic psychosis
0.606 0.394 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.605 0.395 0.000
G44 Other headache syndromes
0.605 0.395 0.000
G41 Status epilepticus
0.605 0.395 0.000
M43 Other deforming dorsopathies
0.605 0.395 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.605 0.395 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.604 0.396 0.000
Z53.8 Procedure not carried out for other reasons
0.604 0.396 0.000
C50-C50 Malignant neoplasm of breast
0.604 0.396 0.000
S68 Traumatic amputation of wrist and hand
0.603 0.397 0.000
Z42 Follow-up care involving plastic surgery
0.603 0.397 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.603 0.397 0.000
M19.98 Arthrosis, unspecified (Other)
0.601 0.399 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.601 0.399 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.601 0.399 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.601 0.399 0.000
S61.1 Open wound of finger(s) with damage to nail
0.601 0.399 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.600 0.400 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.600 0.400 0.000
N97 Female infertility
0.600 0.400 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.600 0.400 0.000
H44 Disorders of globe
0.600 0.400 0.000
H43.3 Other vitreous opacities
0.599 0.401 0.000
M19.94 Arthrosis, unspecified (Hand)
0.599 0.401 0.000
D60-D64 Aplastic and other anaemias
0.599 0.401 0.000
O85-O92 Complications predominantly related to the puerperium
0.598 0.402 0.000
B34 Viral infection of unspecified site
0.598 0.402 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.598 0.402 0.000
E10 Insulin-dependent diabetes mellitus
0.598 0.402 0.000
S50-S59 Injuries to the elbow and forearm
0.597 0.403 0.000
H42 Glaucoma in diseases classified elsewhere
0.597 0.403 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.596 0.404 0.000
L08 Other local infections of skin and subcutaneous tissue
0.596 0.404 0.000
M17.5 Other secondary gonarthrosis
0.596 0.404 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.596 0.404 0.000
M17.3 Other posttraumatic gonarthrosis
0.596 0.404 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.596 0.404 0.000
D50-D53 Nutritional anaemias
0.595 0.405 0.000
M25.51 Pain in joint (Shoulder region)
0.594 0.405 0.000
H43.8 Other disorders of vitreous body
0.594 0.406 0.000
N99-N99 Other disorders of the genitourinary system
0.593 0.407 0.000
L60-L75 Disorders of skin appendages
0.591 0.409 0.000
G47.8 Other sleep disorders
0.591 0.409 0.000
G47.4 Narcolepsy and cataplexy
0.591 0.409 0.000
G47.2 Disorders of the sleep-wake schedule
0.591 0.409 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.591 0.409 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.591 0.409 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.590 0.409 0.000
H80-H83 Diseases of inner ear
0.589 0.410 0.000
M41 Scoliosis
0.589 0.410 0.000
F99 Mental disorder, not otherwise specified
0.588 0.412 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.588 0.412 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.587 0.413 0.000
O00-O08 Pregnancy with abortive outcome
0.586 0.414 0.000
Z54 Convalescence
0.585 0.415 0.000
Z52 Donors of organs and tissues
0.585 0.415 0.000
Z49 Care involving dialysis
0.585 0.415 0.000
Z44 Fitting and adjustment of external prosthetic device
0.585 0.415 0.000
Z41 Procedures for purposes other than remedying health state
0.585 0.415 0.000
Z40 Prophylactic surgery
0.585 0.415 0.000
M17.0 Primary gonarthrosis, bilateral
0.585 0.415 0.000
N98 Complications associated with artificial fertilisation
0.584 0.416 0.000
N91 Absent, scanty and rare menstruation
0.584 0.416 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.584 0.416 0.000
N82 Fistulae involving female genital tract
0.584 0.416 0.000
N96 Habitual aborter
0.584 0.416 0.000
M54.22 Cervicalgia (Cervical region)
0.583 0.417 0.000
H35.9 Retinal disorder, unspecified
0.583 0.417 0.000
H35.7 Separation of retinal layers
0.583 0.417 0.000
H35.6 Retinal haemorrhage
0.583 0.417 0.000
H35.5 Hereditary retinal dystrophy
0.583 0.417 0.000
H35.2 Other proliferative retinopathy
0.583 0.417 0.000
H35.1 Retinopathy of prematurity
0.583 0.417 0.000
H35.0 Background retinopathy and retinal vascular changes
0.583 0.417 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.581 0.419 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.580 0.420 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.580 0.420 0.000
S00-S09 Injuries to the head
0.579 0.421 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.579 0.421 0.000
M14 Arthropathies in other diseases classified elsewhere
0.576 0.424 0.000
M12 Other specific arthropathies
0.576 0.424 0.000
M11 Other crystal arthropathies
0.576 0.424 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.576 0.424 0.000
M08 Juvenile arthritis
0.576 0.424 0.000
M07 Psoriatic and enteropathic arthropathies
0.576 0.424 0.000
M05 Seropositive rheumatoid arthritis
0.576 0.424 0.000
H00 Hordeolum and chalazion
0.576 0.424 0.000
M54.39 Sciatica (Site unspecified)
0.575 0.425 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.575 0.425 0.000
Z45 Adjustment and management of implanted device
0.574 0.426 0.000
M25.79 Osteophyte (Site unspecified)
0.574 0.426 0.000
M25.78 Osteophyte (Other)
0.574 0.426 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.574 0.426 0.000
M25.74 Osteophyte (Hand)
0.574 0.426 0.000
M25.73 Osteophyte (Forearm)
0.574 0.426 0.000
M25.72 Osteophyte (Upper arm)
0.574 0.426 0.000
M25.71 Osteophyte (Shoulder region)
0.574 0.426 0.000
M25.70 Osteophyte (Multiple sites)
0.574 0.426 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.572 0.428 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.572 0.428 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.572 0.428 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.572 0.428 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.572 0.428 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.572 0.428 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.572 0.428 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.572 0.428 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.572 0.428 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.572 0.428 0.000
T36 Poisoning by systemic antibiotics
0.572 0.428 0.000
N95.0 Postmenopausal bleeding
0.572 0.428 0.000
S69 Other and unspecified injuries of wrist and hand
0.572 0.428 0.000
S67 Crushing injury of wrist and hand
0.572 0.428 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.572 0.428 0.000
S65 Injury of blood vessels at wrist and hand level
0.572 0.428 0.000
S64 Injury of nerves at wrist and hand level
0.572 0.428 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.572 0.428 0.000
S60 Superficial injury of wrist and hand
0.572 0.428 0.000
M13 Other arthritis
0.571 0.429 0.000
C51-C58 Malignant neoplasms of female genital organs
0.568 0.432 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.567 0.433 0.000
Z10 Routine general health check-up of defined subpopulation
0.567 0.433 0.000
Z04 Examination and observation for other reasons
0.567 0.433 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.567 0.433 0.000
L20-L30 Dermatitis and eczema
0.566 0.433 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.566 0.434 0.000
E40-E46 Malnutrition
0.563 0.437 0.000
E20-E35 Disorders of other endocrine glands
0.563 0.437 0.000
N10-N16 Renal tubulo-interstitial diseases
0.562 0.438 0.000
M42 Spinal osteochondrosis
0.561 0.439 0.000
M40 Kyphosis and lordosis
0.561 0.439 0.000
N84.9 Polyp of female genital tract, unspecified
0.561 0.439 0.000
N84.8 Polyp of other parts of female genital tract
0.561 0.439 0.000
N84.3 Polyp of vulva
0.561 0.439 0.000
N84.2 Polyp of vagina
0.561 0.439 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.559 0.441 0.000
N80 Endometriosis
0.559 0.441 0.000
N81.5 Vaginal enterocele
0.558 0.442 0.000
M67 Other disorders of synovium and tendon
0.558 0.442 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.557 0.443 0.000
W20-W49 Exposure to inanimate mechanical forces
0.555 0.444 0.000
J40-J47 Chronic lower respiratory diseases
0.555 0.445 0.000
E50-E64 Other nutritional deficiencies
0.555 0.445 0.000
N00-N08 Glomerular diseases
0.555 0.445 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.554 0.445 0.000
M50.9 Cervical disk disorder, unspecified
0.554 0.446 0.000
M50.8 Other cervical disk disorders
0.554 0.446 0.000
M50.1 Cervical disk disorder with radiculopathy
0.554 0.446 0.000
M50.0 Cervical disk disorder with myelopathy
0.554 0.446 0.000
M54.56 Low back pain (Lumbar region)
0.554 0.446 0.000
A04 Other bacterial intestinal infections
0.553 0.447 0.000
H26.4 After-cataract
0.553 0.447 0.000
Z48.0 Attention to surgical dressings and sutures
0.552 0.448 0.000
S62 Fracture at wrist and hand level
0.551 0.449 0.000
H43.1 Vitreous haemorrhage
0.551 0.449 0.000
M54.59 Low back pain (Site unspecified)
0.551 0.449 0.000
M54.57 Low back pain (Lumbosacral region)
0.551 0.449 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.550 0.450 0.000
M49 Spondylopathies in diseases classified elsewhere
0.549 0.451 0.000
M46 Other inflammatory spondylopathies
0.549 0.451 0.000
M45 Ankylosing spondylitis
0.549 0.451 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.549 0.451 0.000
M20.1 Hallux valgus (acquired)
0.549 0.451 0.000
A49 Bacterial infection of unspecified site
0.548 0.452 0.000
A48 Other bacterial diseases, not elsewhere classified
0.548 0.452 0.000
A44 Bartonellosis
0.548 0.452 0.000
A43 Nocardiosis
0.548 0.452 0.000
A42 Actinomycosis
0.548 0.452 0.000
A40 Streptococcal septicaemia
0.548 0.452 0.000
A39 Meningococcal infection
0.548 0.452 0.000
A37 Whooping cough
0.548 0.452 0.000
A36 Diphtheria
0.548 0.452 0.000
A32 Listeriosis
0.548 0.452 0.000
A31 Infection due to other mycobacteria
0.548 0.452 0.000
A30 Leprosy [Hansen's disease]
0.548 0.452 0.000
A46 Erysipelas
0.548 0.452 0.000
A38 Scarlet fever
0.548 0.452 0.000
A35 Other tetanus
0.548 0.452 0.000
A34 Obstetrical tetanus
0.548 0.452 0.000
A33 Tetanus neonatorum
0.548 0.452 0.000
Z50 Care involving use of rehabilitation procedures
0.547 0.453 0.000
O80-O84 Delivery
0.547 0.453 0.000
M16.7 Other secondary coxarthrosis
0.546 0.454 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.546 0.454 0.000
M16.5 Other posttraumatic coxarthrosis
0.546 0.454 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.546 0.454 0.000
M16.3 Other dysplastic coxarthrosis
0.546 0.454 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.546 0.454 0.000
M16.0 Primary coxarthrosis, bilateral
0.546 0.454 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.546 0.454 0.000
M23.37 Other meniscus derangements-Capsular lig
0.546 0.454 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.546 0.454 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.546 0.454 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.546 0.454 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.545 0.455 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.545 0.455 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.545 0.455 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.545 0.455 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.545 0.455 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.545 0.455 0.000
C50 Malignant neoplasm of breast
0.545 0.455 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.544 0.456 0.000
M80 Osteoporosis with pathological fracture
0.542 0.457 0.000
E14 Unspecified diabetes mellitus
0.542 0.458 0.000
S32 Fracture of lumbar spine and pelvis
0.541 0.459 0.000
M25.49 Effusion of joint (Site unspecified)
0.541 0.459 0.000
M25.48 Effusion of joint (Other)
0.541 0.459 0.000
M25.47 Effusion of joint (Ankle and foot)
0.541 0.459 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.541 0.459 0.000
M25.44 Effusion of joint (Hand)
0.541 0.459 0.000
M25.43 Effusion of joint (Forearm)
0.541 0.459 0.000
M25.42 Effusion of joint (Upper arm)
0.541 0.459 0.000
M25.41 Effusion of joint (Shoulder region)
0.541 0.459 0.000
M25.40 Effusion of joint (Multiple sites)
0.541 0.459 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.540 0.459 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.540 0.459 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.540 0.459 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.540 0.459 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.540 0.459 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.540 0.459 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.540 0.459 0.000
F11 Mental and behavioural disorders due to use of opioids
0.540 0.459 0.000
E11 Non-insulin-dependent diabetes mellitus
0.540 0.460 0.000
H40.0 Glaucoma suspect
0.539 0.461 0.000
B33 Other viral diseases, not elsewhere classified
0.538 0.461 0.000
B30 Viral conjunctivitis
0.538 0.461 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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