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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138477082
log Bayes Factor = 2.62368
Chromosome 12   position 103,796,611  (GRCh37) Explore rs138477082 on Ensembl!
Variant rs138477082 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
I20-I25 Ischaemic heart diseases
0.981 0.019 0.000
I60-I69 Cerebrovascular diseases
0.971 0.029 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.965 0.035 0.000
M45-M49 Spondylopathies
0.961 0.039 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.953 0.047 0.000
M47 Spondylosis
0.937 0.063 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.929 0.071 0.000
I25 Chronic ischaemic heart disease
0.929 0.071 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.929 0.071 0.000
M47.8 Other spondylosis
0.928 0.072 0.000
M47.82 Other spondylosis (Cervical region)
0.924 0.076 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.919 0.081 0.000
I21 Acute myocardial infarction
0.912 0.088 0.000
Chapter VIII Diseases of the ear and mastoid process
0.909 0.091 0.000
M80-M85 Disorders of bone density and structure
0.909 0.091 0.000
G81 Hemiplegia
0.909 0.091 0.000
H30-H36 Disorders of choroid and retina
0.906 0.094 0.000
O60-O75 Complications of labour and delivery
0.902 0.098 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.899 0.101 0.000
M40-M43 Deforming dorsopathies
0.898 0.102 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.884 0.116 0.000
G40-G47 Episodic and paroxysmal disorders
0.883 0.117 0.000
H53-H54 Visual disturbances and blindness
0.879 0.121 0.000
G83 Other paralytic syndromes
0.878 0.122 0.000
O00-O08 Pregnancy with abortive outcome
0.877 0.123 0.000
H43-H45 Disorders of vitreous body and globe
0.874 0.126 0.000
G81.9 Hemiplegia, unspecified
0.870 0.130 0.000
I63 Cerebral infarction
0.868 0.132 0.000
I73 Other peripheral vascular diseases
0.866 0.134 0.000
I67 Other cerebrovascular diseases
0.859 0.141 0.000
O42 Premature rupture of membranes
0.835 0.165 0.000
H52 Disorders of refraction and accommodation
0.833 0.167 0.000
I78 Diseases of capillaries
0.826 0.174 0.000
H33 Retinal detachments and breaks
0.824 0.176 0.000
G90-G99 Other disorders of the nervous system
0.822 0.178 0.000
G83.4 Cauda equina syndrome
0.817 0.183 0.000
G43 Migraine
0.814 0.186 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.813 0.187 0.000
H60-H62 Diseases of external ear
0.812 0.188 0.000
I25.2 Old myocardial infarction
0.811 0.189 0.000
O16 Unspecified maternal hypertension
0.809 0.191 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.806 0.194 0.000
H90-H95 Other disorders of ear
0.806 0.194 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.800 0.200 0.000
I67.9 Cerebrovascular disease, unspecified
0.797 0.203 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.795 0.205 0.000
H43 Disorders of vitreous body
0.791 0.209 0.000
H54 Blindness and low vision
0.789 0.211 0.000
M43 Other deforming dorsopathies
0.789 0.211 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.788 0.212 0.000
H50 Other strabismus
0.787 0.213 0.000
I60 Subarachnoid haemorrhage
0.785 0.215 0.000
H16 Keratitis
0.783 0.217 0.000
H55-H59 Other disorders of eye and adnexa
0.783 0.217 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.782 0.218 0.000
H21 Other disorders of iris and ciliary body
0.782 0.218 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.782 0.218 0.000
H18 Other disorders of cornea
0.779 0.220 0.000
H35 Other retinal disorders
0.779 0.221 0.000
M81 Osteoporosis without pathological fracture
0.777 0.223 0.000
G43.9 Migraine, unspecified
0.775 0.225 0.000
I77 Other disorders of arteries and arterioles
0.769 0.231 0.000
I24 Other acute ischaemic heart diseases
0.768 0.232 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.765 0.235 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.764 0.236 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.764 0.236 0.000
I73.9 Peripheral vascular disease, unspecified
0.764 0.236 0.000
O03 Spontaneous abortion
0.763 0.237 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
M45 Ankylosing spondylitis
0.759 0.240 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.756 0.244 0.000
M41 Scoliosis
0.755 0.245 0.000
I05-I09 Chronic rheumatic heart diseases
0.753 0.247 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.752 0.248 0.000
H43.8 Other disorders of vitreous body
0.748 0.252 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.746 0.254 0.000
M60-M63 Disorders of muscles
0.746 0.254 0.000
O66 Other obstructed labour
0.740 0.260 0.000
M65-M68 Disorders of synovium and tendon
0.739 0.261 0.000
H10-H13 Disorders of conjunctiva
0.736 0.264 0.000
H52.1 Myopia
0.736 0.264 0.000
O63 Long labour
0.732 0.268 0.000
O70 Perineal laceration during delivery
0.729 0.271 0.000
H90 Conductive and sensorineural hearing loss
0.729 0.271 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.729 0.271 0.000
M85 Other disorders of bone density and structure
0.728 0.272 0.000
M46 Other inflammatory spondylopathies
0.726 0.274 0.000
H33.3 Retinal breaks without detachment
0.726 0.274 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.723 0.277 0.000
M05-M14 Inflammatory polyarthropathies
0.723 0.277 0.000
O41 Other disorders of amniotic fluid and membranes
0.720 0.280 0.000
I25.5 Ischaemic cardiomyopathy
0.718 0.282 0.000
O42.9 Premature rupture of membranes, unspecified
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.282 0.000
I73.0 Raynaud's syndrome
0.717 0.283 0.000
M84 Disorders of continuity of bone
0.716 0.284 0.000
M80 Osteoporosis with pathological fracture
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.715 0.285 0.000
I63.9 Cerebral infarction, unspecified
0.715 0.285 0.000
O02 Other abnormal products of conception
0.715 0.285 0.000
I69 Sequelae of cerebrovascular disease
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
I22 Subsequent myocardial infarction
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
G20-G26 Extrapyramidal and movement disorders
0.712 0.288 0.000
I62 Other nontraumatic intracranial haemorrhage
0.711 0.289 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.709 0.291 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
O23 Infections of genito-urinary tract in pregnancy
0.707 0.293 0.000
G82 Paraplegia and tetraplegia
0.706 0.294 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.705 0.295 0.000
H61 Other disorders of external ear
0.704 0.296 0.000
G70-G73 Diseases of myoneural junction and muscle
0.704 0.296 0.000
I23 Certain current complications following acute myocardial infarction
0.703 0.297 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.702 0.298 0.000
I74 Arterial embolism and thrombosis
0.701 0.299 0.000
I72 Other aneurysm
0.699 0.300 0.000
I70 Atherosclerosis
0.697 0.303 0.000
O24 Diabetes mellitus in pregnancy
0.696 0.303 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.304 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.695 0.305 0.000
S50-S59 Injuries to the elbow and forearm
0.695 0.305 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.693 0.307 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.693 0.307 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.692 0.308 0.000
G80 Infantile cerebral palsy
0.692 0.308 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.692 0.308 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.691 0.309 0.000
H49 Paralytic strabismus
0.690 0.309 0.000
M49 Spondylopathies in diseases classified elsewhere
0.689 0.311 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.688 0.312 0.000
O20 Haemorrhage in early pregnancy
0.686 0.314 0.000
M43.1 Spondylolisthesis
0.686 0.314 0.000
H35.9 Retinal disorder, unspecified
0.685 0.315 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.684 0.316 0.000
H52.0 Hypermetropia
0.683 0.317 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.681 0.319 0.000
I20 Angina pectoris
0.680 0.320 0.000
H54.9 Unspecified visual impairment (binocular)
0.679 0.321 0.000
H16.0 Corneal ulcer
0.679 0.321 0.000
I21.4 Acute subendocardial myocardial infarction
0.678 0.322 0.000
Chapter I Certain infectious and parasitic diseases
0.678 0.322 0.000
O62 Abnormalities of forces of labour
0.676 0.324 0.000
M48 Other spondylopathies
0.676 0.324 0.000
G30-G32 Other degenerative diseases of the nervous system
0.675 0.325 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.673 0.327 0.000
I78.1 Naevus, nonneoplastic
0.673 0.327 0.000
M81.9 Osteoporosis, unspecified
0.672 0.328 0.000
M47.1 Other spondylosis with myelopathy
0.672 0.328 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.672 0.328 0.000
S20-S29 Injuries to the thorax
0.670 0.330 0.000
M47.86 Other spondylosis (Lumbar region)
0.669 0.331 0.000
H51 Other disorders of binocular movement
0.666 0.334 0.000
I25.6 Silent myocardial ischaemia
0.666 0.334 0.000
I25.4 Coronary artery aneurysm
0.666 0.334 0.000
I25.3 Aneurysm of heart
0.666 0.334 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.666 0.334 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.666 0.334 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.666 0.334 0.000
H17 Corneal scars and opacities
0.666 0.334 0.000
H15 Disorders of sclera
0.666 0.334 0.000
M47.89 Other spondylosis (Site unspecified)
0.665 0.335 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.665 0.335 0.000
M47.84 Other spondylosis (Thoracic region)
0.665 0.335 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.665 0.335 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.665 0.335 0.000
M70-M79 Other soft tissue disorders
0.665 0.335 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.664 0.336 0.000
H50.9 Strabismus, unspecified
0.664 0.336 0.000
H60 Otitis externa
0.662 0.338 0.000
O34.1 Maternal care for tumour of corpus uteri
0.661 0.339 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.661 0.339 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.661 0.339 0.000
H54.0 Blindness, both eyes
0.661 0.339 0.000
O45 Premature separation of placenta [abruptio placentae]
0.659 0.341 0.000
O44 Placenta praevia
0.659 0.341 0.000
O43 Placental disorders
0.659 0.341 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.659 0.341 0.000
O33 Maternal care for known or suspected disproportion
0.659 0.341 0.000
O31 Complications specific to multiple gestation
0.659 0.341 0.000
O30 Multiple gestation
0.659 0.341 0.000
O40 Polyhydramnios
0.659 0.341 0.000
H33.0 Retinal detachment with retinal break
0.658 0.342 0.000
G91 Hydrocephalus
0.658 0.342 0.000
H35.6 Retinal haemorrhage
0.657 0.343 0.000
I61 Intracerebral haemorrhage
0.657 0.343 0.000
H50.0 Convergent concomitant strabismus
0.656 0.344 0.000
H90.5 Sensorineural hearing loss, unspecified
0.655 0.345 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.654 0.345 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.654 0.346 0.000
H20 Iridocyclitis
0.654 0.346 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.654 0.346 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.654 0.346 0.000
M41.9 Scoliosis, unspecified
0.653 0.347 0.000
I80 Phlebitis and thrombophlebitis
0.653 0.347 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.652 0.348 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.652 0.348 0.000
M83 Adult osteomalacia
0.652 0.348 0.000
M82 Osteoporosis in diseases classified elsewhere
0.652 0.348 0.000
G81.1 Spastic hemiplegia
0.652 0.348 0.000
G81.0 Flaccid hemiplegia
0.652 0.348 0.000
O03.9 Complete or unspecified, without complication
0.652 0.348 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.652 0.348 0.000
H18.1 Bullous keratopathy
0.651 0.349 0.000
G93 Other disorders of brain
0.650 0.350 0.000
I25.1 Atherosclerotic heart disease
0.650 0.350 0.000
H53 Visual disturbances
0.650 0.350 0.000
G51 Facial nerve disorders
0.650 0.350 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.649 0.351 0.000
H31 Other disorders of choroid
0.649 0.351 0.000
H30 Chorioretinal inflammation
0.649 0.351 0.000
M10 Gout
0.647 0.353 0.000
O74 Complications of anaesthesia during labour and delivery
0.647 0.353 0.000
O71 Other obstetric trauma
0.647 0.353 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.647 0.353 0.000
O61 Failed induction of labour
0.647 0.353 0.000
O60 Preterm delivery
0.647 0.353 0.000
G45.4 Transient global amnesia
0.647 0.353 0.000
S00-S09 Injuries to the head
0.645 0.355 0.000
O63.1 Prolonged second stage (of labour)
0.645 0.355 0.000
O15 Eclampsia
0.644 0.356 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.644 0.356 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.644 0.356 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.644 0.356 0.000
M42 Spinal osteochondrosis
0.643 0.356 0.000
M40 Kyphosis and lordosis
0.643 0.356 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.642 0.358 0.000
M47.2 Other spondylosis with radiculopathy
0.640 0.360 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.639 0.361 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.639 0.361 0.000
H61.2 Impacted cerumen
0.638 0.362 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.636 0.363 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.636 0.364 0.000
H40-H42 Glaucoma
0.634 0.365 0.000
H21.8 Other specified disorders of iris and ciliary body
0.634 0.366 0.000
O29 Complications of anaesthesia during pregnancy
0.634 0.366 0.000
O28 Abnormal findings on antenatal screening of mother
0.634 0.366 0.000
O22 Venous complications in pregnancy
0.634 0.366 0.000
O21 Excessive vomiting in pregnancy
0.634 0.366 0.000
O25 Malnutrition in pregnancy
0.634 0.366 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.633 0.367 0.000
G41 Status epilepticus
0.633 0.367 0.000
O70.0 First degree perineal laceration during delivery
0.631 0.369 0.000
G83.9 Paralytic syndrome, unspecified
0.630 0.370 0.000
G83.8 Other specified paralytic syndromes
0.630 0.370 0.000
G83.5 Locked-in syndrome
0.630 0.370 0.000
G83.3 Monoplegia, unspecified
0.630 0.370 0.000
G83.2 Monoplegia of upper limb
0.630 0.370 0.000
G83.1 Monoplegia of lower limb
0.630 0.370 0.000
G83.0 Diplegia of upper limbs
0.630 0.370 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.629 0.371 0.000
O07 Failed attempted abortion
0.629 0.371 0.000
O06 Unspecified abortion
0.629 0.371 0.000
O05 Other abortion
0.629 0.371 0.000
O01 Hydatidiform mole
0.629 0.371 0.000
O00 Ectopic pregnancy
0.629 0.371 0.000
H92 Otalgia and effusion of ear
0.627 0.373 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.626 0.374 0.000
O73 Retained placenta and membranes, without haemorrhage
0.625 0.375 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.624 0.376 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.624 0.376 0.000
S90-S99 Injuries to the ankle and foot
0.624 0.376 0.000
H34 Retinal vascular occlusions
0.623 0.377 0.000
G44 Other headache syndromes
0.623 0.377 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.622 0.378 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.622 0.378 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.622 0.378 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.622 0.378 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.622 0.378 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.622 0.378 0.000
H33.2 Serous retinal detachment
0.621 0.379 0.000
I73.8 Other specified peripheral vascular diseases
0.621 0.379 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.621 0.379 0.000
I21.9 Acute myocardial infarction, unspecified
0.619 0.381 0.000
M43.0 Spondylolysis
0.619 0.381 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.619 0.381 0.000
I77.1 Stricture of artery
0.617 0.383 0.000
H35.0 Background retinopathy and retinal vascular changes
0.617 0.383 0.000
I63.8 Other cerebral infarction
0.616 0.384 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.616 0.384 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.616 0.384 0.000
I67.5 Moyamoya disease
0.616 0.384 0.000
I67.4 Hypertensive encephalopathy
0.616 0.384 0.000
I67.3 Progressive vascular leukoencephalopathy
0.616 0.384 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.616 0.384 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.615 0.385 0.000
H93 Other disorders of ear, not elsewhere classified
0.612 0.388 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.611 0.389 0.000
H44 Disorders of globe
0.611 0.389 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.611 0.389 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.610 0.390 0.000
H57 Other disorders of eye and adnexa
0.609 0.391 0.000
I67.1 Cerebral aneurysm, nonruptured
0.609 0.391 0.000
I71 Aortic aneurysm and dissection
0.608 0.391 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.606 0.394 0.000
G25 Other extrapyramidal and movement disorders
0.606 0.394 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.606 0.394 0.000
S52 Fracture of forearm
0.605 0.395 0.000
O03.4 Incomplete, without complication
0.604 0.396 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.604 0.396 0.000
G47 Sleep disorders
0.603 0.397 0.000
S10-S19 Injuries to the neck
0.602 0.398 0.000
I67.8 Other specified cerebrovascular diseases
0.602 0.398 0.000
I20.0 Unstable angina
0.602 0.398 0.000
M88 Paget's disease of bone [osteitis deformans]
0.601 0.399 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.600 0.400 0.000
O02.1 Missed abortion
0.599 0.401 0.000
H18.4 Corneal degeneration
0.599 0.401 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.599 0.401 0.000
M85.8 Other specified disorders of bone density and structure
0.598 0.402 0.000
H52.7 Disorder of refraction, unspecified
0.597 0.403 0.000
H52.6 Other disorders of refraction
0.597 0.403 0.000
H52.5 Disorders of accommodation
0.597 0.403 0.000
H52.4 Presbyopia
0.597 0.403 0.000
H52.3 Anisometropia and aniseikonia
0.597 0.403 0.000
I86 Varicose veins of other sites
0.597 0.403 0.000
H54.7 Unspecified visual loss
0.596 0.404 0.000
H33.5 Other retinal detachments
0.596 0.404 0.000
O04 Medical abortion
0.594 0.406 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.593 0.407 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.593 0.407 0.000
I78.9 Disease of capillaries, unspecified
0.592 0.407 0.000
I78.8 Other diseases of capillaries
0.592 0.407 0.000
M10.9 Gout, unspecified
0.592 0.408 0.000
Chapter XX External causes of morbidity and mortality
0.592 0.408 0.000
B35-B49 Mycoses
0.591 0.409 0.000
H33.4 Traction detachment of retina
0.590 0.409 0.000
H33.1 Retinoschisis and retinal cysts
0.590 0.409 0.000
O47 False labour
0.590 0.410 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.590 0.410 0.000
G96 Other disorders of central nervous system
0.590 0.410 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.590 0.410 0.000
G90 Disorders of autonomic nervous system
0.590 0.410 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.590 0.410 0.000
G92 Toxic encephalopathy
0.590 0.410 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.590 0.410 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.589 0.411 0.000
G95 Other diseases of spinal cord
0.589 0.411 0.000
T66-T78 Other and unspecified effects of external causes
0.587 0.412 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.587 0.413 0.000
H47.3 Other disorders of optic disk
0.587 0.413 0.000
H65-H75 Diseases of middle ear and mastoid
0.584 0.416 0.000
G43.8 Other migraine
0.584 0.416 0.000
G43.3 Complicated migraine
0.584 0.416 0.000
G43.2 Status migrainosus
0.584 0.416 0.000
G43.0 Migraine without aura [common migraine]
0.584 0.416 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.584 0.416 0.000
H80-H83 Diseases of inner ear
0.583 0.417 0.000
I77.8 Other specified disorders of arteries and arterioles
0.583 0.417 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.583 0.417 0.000
H46 Optic neuritis
0.583 0.417 0.000
I24.8 Other forms of acute ischaemic heart disease
0.582 0.417 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.582 0.418 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.581 0.419 0.000
G51.0 Bell's palsy
0.581 0.419 0.000
O48 Prolonged pregnancy
0.580 0.420 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.580 0.420 0.000
M81.4 Drug-induced osteoporosis
0.578 0.421 0.000
O41.0 Oligohydramnios
0.578 0.422 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.578 0.422 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.578 0.422 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.577 0.423 0.000
H90.2 Conductive hearing loss, unspecified
0.576 0.424 0.000
M62 Other disorders of muscle
0.576 0.424 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.576 0.424 0.000
Q80-Q89 Other congenital malformations
0.575 0.424 0.000
O26.9 Pregnancy-related condition, unspecified
0.575 0.425 0.000
I74.8 Embolism and thrombosis of other arteries
0.575 0.425 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.575 0.425 0.000
H43.1 Vitreous haemorrhage
0.573 0.427 0.000
I67.2 Cerebral atherosclerosis
0.572 0.428 0.000
H04 Disorders of lachrymal system
0.571 0.429 0.000
M89 Other disorders of bone
0.571 0.429 0.000
G56 Mononeuropathies of upper limb
0.570 0.430 0.000
T33-T35 Frostbite
0.570 0.430 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.570 0.430 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.570 0.430 0.000
T00-T07 Injuries involving multiple body regions
0.570 0.430 0.000
H53.4 Visual field defects
0.569 0.431 0.000
I08 Multiple valve diseases
0.568 0.432 0.000
H43.9 Disorder of vitreous body, unspecified
0.567 0.433 0.000
H43.2 Crystalline deposits in vitreous body
0.567 0.433 0.000
H43.0 Vitreous prolapse
0.567 0.433 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.566 0.433 0.000
H52.2 Astigmatism
0.566 0.434 0.000
H54.6 Unqualified visual loss, one eye
0.565 0.434 0.000
H54.5 Low vision, one eye
0.565 0.434 0.000
H54.3 Unqualified visual loss, both eyes
0.565 0.434 0.000
H54.2 Low vision, both eyes
0.565 0.434 0.000
H54.1 Blindness, one eye, low vision, other eye
0.565 0.434 0.000
M43.9 Deforming dorsopathy, unspecified
0.565 0.434 0.000
M43.8 Other specified deforming dorsopathies
0.565 0.434 0.000
M43.6 Torticollis
0.565 0.434 0.000
M43.5 Other recurrent vertebral subluxation
0.565 0.434 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.565 0.434 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.565 0.434 0.000
M43.2 Other fusion of spine
0.565 0.434 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.565 0.435 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.565 0.435 0.000
O34.6 Maternal care for abnormality of vagina
0.565 0.435 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.565 0.435 0.000
O34.4 Maternal care for other abnormalities of cervix
0.565 0.435 0.000
O34.3 Maternal care for cervical incompetence
0.565 0.435 0.000
O34.0 Maternal care for congenital malformation of uterus
0.565 0.435 0.000
H50.8 Other specified strabismus
0.564 0.436 0.000
H50.6 Mechanical strabismus
0.564 0.436 0.000
H50.5 Heterophoria
0.564 0.436 0.000
H50.4 Other and unspecified heterotropia
0.564 0.436 0.000
H50.3 Intermittent heterotropia
0.564 0.436 0.000
H50.2 Vertical strabismus
0.564 0.436 0.000
S60-S69 Injuries to the wrist and hand
0.563 0.437 0.000
M50-M54 Other dorsopathies
0.563 0.437 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.563 0.437 0.000
S52.6 Fracture of lower end of both ulna and radius
0.563 0.437 0.000
I60.8 Other subarachnoid haemorrhage
0.563 0.437 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.563 0.437 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.563 0.437 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.563 0.437 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.563 0.437 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.563 0.437 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.563 0.437 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.563 0.437 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.563 0.437 0.000
M66 Spontaneous rupture of synovium and tendon
0.563 0.437 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.562 0.438 0.000
H16.9 Keratitis, unspecified
0.561 0.439 0.000
H16.8 Other keratitis
0.561 0.439 0.000
H16.4 Corneal neovascularisation
0.561 0.439 0.000
H16.3 Interstitial and deep keratitis
0.561 0.439 0.000
H16.2 Keratoconjunctivitis
0.561 0.439 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.561 0.439 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.561 0.439 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.560 0.439 0.000
H21.4 Pupillary membranes
0.560 0.439 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.560 0.439 0.000
H21.2 Degeneration of iris and ciliary body
0.560 0.439 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.560 0.439 0.000
H21.0 Hyphaema
0.560 0.439 0.000
H01 Other inflammation of eyelid
0.560 0.440 0.000
H18.9 Disorder of cornea, unspecified
0.559 0.441 0.000
H18.8 Other specified disorders of cornea
0.559 0.441 0.000
H18.7 Other corneal deformities
0.559 0.441 0.000
H18.6 Keratoconus
0.559 0.441 0.000
H18.3 Changes in corneal membranes
0.559 0.441 0.000
H18.2 Other corneal oedema
0.559 0.441 0.000
H18.0 Corneal pigmentations and deposits
0.559 0.441 0.000
H35.7 Separation of retinal layers
0.559 0.441 0.000
H35.5 Hereditary retinal dystrophy
0.559 0.441 0.000
H35.2 Other proliferative retinopathy
0.559 0.441 0.000
H35.1 Retinopathy of prematurity
0.559 0.441 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.558 0.442 0.000
H10 Conjunctivitis
0.557 0.442 0.000
M81.8 Other osteoporosis
0.557 0.443 0.000
M81.6 Localised osteoporosis [Lequesne]
0.557 0.443 0.000
M81.5 Idiopathic osteoporosis
0.557 0.443 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.557 0.443 0.000
M81.2 Osteoporosis of disuse
0.557 0.443 0.000
M81.1 Postoophorectomy osteoporosis
0.557 0.443 0.000
M81.0 Postmenopausal osteoporosis
0.557 0.443 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.555 0.445 0.000
H18.5 Hereditary corneal dystrophies
0.555 0.445 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.555 0.445 0.000
H60.9 Otitis externa, unspecified
0.555 0.445 0.000
M65 Synovitis and tenosynovitis
0.555 0.445 0.000
O36 Maternal care for other known or suspected foetal problems
0.554 0.446 0.000
O80-O84 Delivery
0.552 0.447 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.552 0.448 0.000
I07 Rheumatic tricuspid valve diseases
0.552 0.448 0.000
I77.5 Necrosis of artery
0.551 0.448 0.000
I77.4 Coeliac artery compression syndrome
0.551 0.448 0.000
I77.3 Arterial fibromuscular dysplasia
0.551 0.448 0.000
I77.2 Rupture of artery
0.551 0.448 0.000
I77.0 Arteriovenous fistula, acquired
0.551 0.448 0.000
I77.6 Arteritis, unspecified
0.551 0.449 0.000
I24.1 Dressler's syndrome
0.550 0.449 0.000
O70.2 Third degree perineal laceration during delivery
0.550 0.450 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.549 0.451 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.549 0.451 0.000
G45.3 Amaurosis fugax
0.549 0.451 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.549 0.451 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.549 0.451 0.000
G45.0 Vertebro-basilar artery syndrome
0.549 0.451 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.548 0.452 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.548 0.452 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.548 0.452 0.000
Q35-Q37 Cleft lip and cleft palate
0.548 0.452 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.548 0.452 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.548 0.452 0.000
Q00-Q07 Congenital malformations of the nervous system
0.548 0.452 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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