TreeWAS – Variant ID: rs138556413

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.999	0.001	0.000
I25 Chronic ischaemic heart disease	0.999	0.001	0.000
I20-I25 Ischaemic heart diseases	0.997	0.003	0.000
I21 Acute myocardial infarction	0.977	0.023	0.000
I20 Angina pectoris	0.970	0.030	0.000
I25.2 Old myocardial infarction	0.964	0.036	0.000
I21.9 Acute myocardial infarction, unspecified	0.961	0.039	0.000
I20.9 Angina pectoris, unspecified	0.951	0.049	0.000
I22 Subsequent myocardial infarction	0.888	0.112	0.000
I20.0 Unstable angina	0.853	0.147	0.000
I24 Other acute ischaemic heart diseases	0.851	0.149	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.814	0.186	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.785	0.215	0.000
I25.3 Aneurysm of heart	0.772	0.228	0.000
I21.4 Acute subendocardial myocardial infarction	0.766	0.234	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.762	0.238	0.000
I22.8 Subsequent myocardial infarction of other sites	0.742	0.258	0.000
I25.6 Silent myocardial ischaemia	0.716	0.284	0.000
I25.4 Coronary artery aneurysm	0.716	0.284	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.716	0.284	0.000
I23 Certain current complications following acute myocardial infarction	0.715	0.285	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.700	0.300	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.700	0.300	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.700	0.300	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.665	0.335	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.642	0.358	0.000
I25.5 Ischaemic cardiomyopathy	0.618	0.382	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.610	0.389	0.000
I24.1 Dressler's syndrome	0.610	0.390	0.000
I20.1 Angina pectoris with documented spasm	0.609	0.391	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.597	0.403	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.593	0.406	0.000
I24.8 Other forms of acute ischaemic heart disease	0.581	0.419	0.000
I23.8 Other current complications following acute myocardial infarction	0.513	0.487	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.513	0.487	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.513	0.487	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.513	0.487	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.513	0.487	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.513	0.487	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.513	0.487	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.513	0.487	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.511	0.489	0.000
I20.8 Other forms of angina pectoris	0.485	0.515	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.208	0.792	0.000
M20.1 Hallux valgus (acquired)	0.000	0.863	0.137
M20 Acquired deformities of fingers and toes	0.000	0.868	0.132
M20.5 Other deformities of toe(s) (acquired)	0.000	0.875	0.125
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.877	0.122
M20.0 Deformity of finger(s)	0.000	0.885	0.115
M20.4 Other hammer toe(s) (acquired)	0.000	0.888	0.112
M20.3 Other deformity of hallux (acquired)	0.000	0.913	0.087
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.920	0.080
G40-G47 Episodic and paroxysmal disorders	0.000	0.920	0.080
G43.9 Migraine, unspecified	0.000	0.921	0.079
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.921	0.079
G43 Migraine	0.000	0.922	0.078
G47 Sleep disorders	0.000	0.922	0.078
G47.3 Sleep apnoea	0.000	0.928	0.072
G47.9 Sleep disorder, unspecified	0.000	0.928	0.072
G40 Epilepsy	0.000	0.937	0.063
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.943	0.057
G41 Status epilepticus	0.000	0.943	0.057
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.943	0.056
G45.3 Amaurosis fugax	0.000	0.943	0.056
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.943	0.056
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.943	0.056
G45.0 Vertebro-basilar artery syndrome	0.000	0.943	0.056
G43.8 Other migraine	0.000	0.944	0.056
G43.3 Complicated migraine	0.000	0.944	0.056
G43.2 Status migrainosus	0.000	0.944	0.056
G43.0 Migraine without aura [common migraine]	0.000	0.944	0.056
G47.8 Other sleep disorders	0.000	0.944	0.056
G47.4 Narcolepsy and cataplexy	0.000	0.944	0.056
G47.2 Disorders of the sleep-wake schedule	0.000	0.944	0.056
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.945	0.055
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.946	0.054
G44 Other headache syndromes	0.000	0.947	0.052
Chapter IX Diseases of the circulatory system	0.052	0.948	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.950	0.050
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.952	0.048
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.952	0.048
G45.4 Transient global amnesia	0.000	0.952	0.048
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.048	0.952	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.047	0.953	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.954	0.045
G40.5 Special epileptic syndromes	0.000	0.954	0.045
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.954	0.045
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.954	0.045
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.955	0.045
G43.1 Migraine with aura [classical migraine]	0.000	0.956	0.044
G40.8 Other epilepsy	0.000	0.956	0.044
O70.1 Second degree perineal laceration during delivery	0.000	0.958	0.042
I95 Hypotension	0.042	0.958	0.000
G41.9 Status epilepticus, unspecified	0.000	0.959	0.041
G41.8 Other status epilepticus	0.000	0.959	0.041
G41.2 Complex partial status epilepticus	0.000	0.959	0.041
G41.1 Petit mal status epilepticus	0.000	0.959	0.041
G41.0 Grand mal status epilepticus	0.000	0.959	0.041
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.959	0.041
G46.7 Other lacunar syndromes	0.000	0.959	0.041
G46.6 Pure sensory lacunar syndrome	0.000	0.959	0.041
G46.5 Pure motor lacunar syndrome	0.000	0.959	0.041
G46.4 Cerebellar stroke syndrome	0.000	0.959	0.041
G46.3 Brain stem stroke syndrome	0.000	0.959	0.041
G46.2 Posterior cerebral artery syndrome	0.000	0.959	0.041
G46.1 Anterior cerebral artery syndrome	0.000	0.959	0.041
G46.0 Middle cerebral artery syndrome	0.000	0.959	0.041
I26 Pulmonary embolism	0.041	0.959	0.000
I27 Other pulmonary heart diseases	0.041	0.959	0.000
I05-I09 Chronic rheumatic heart diseases	0.040	0.960	0.000
I95.1 Orthostatic hypotension	0.040	0.960	0.000
M20.2 Hallux rigidus	0.000	0.961	0.039
G44.8 Other specified headache syndromes	0.000	0.962	0.038
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.962	0.038
G44.3 Chronic posttraumatic headache	0.000	0.962	0.038
G44.1 Vascular headache, not elsewhere classified	0.000	0.962	0.038
I00-I02 Acute rheumatic fever	0.038	0.962	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.037	0.963	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.037	0.963	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.037	0.963	0.000
G44.0 Cluster headache syndrome	0.000	0.963	0.036
G44.2 Tension-type headache	0.000	0.965	0.035
I27.0 Primary pulmonary hypertension	0.035	0.965	0.000
G40.9 Epilepsy, unspecified	0.000	0.965	0.035
I05 Rheumatic mitral valve diseases	0.035	0.965	0.000
I28 Other diseases of pulmonary vessels	0.034	0.965	0.000
I27.2 Other secondary pulmonary hypertension	0.034	0.966	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.032	0.968	0.000
O70 Perineal laceration during delivery	0.000	0.968	0.032
O70.0 First degree perineal laceration during delivery	0.000	0.969	0.031
I95.8 Other hypotension	0.030	0.970	0.000
I95.0 Idiopathic hypotension	0.030	0.970	0.000
I73 Other peripheral vascular diseases	0.030	0.970	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.030	0.970	0.000
I08 Multiple valve diseases	0.030	0.970	0.000
I05.1 Rheumatic mitral insufficiency	0.030	0.970	0.000
I99 Other and unspecified disorders of circulatory system	0.030	0.970	0.000
I27.8 Other specified pulmonary heart diseases	0.030	0.970	0.000
I27.1 Kyphoscoliotic heart disease	0.030	0.970	0.000
I73.9 Peripheral vascular disease, unspecified	0.030	0.970	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.029	0.970	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.029	0.970	0.000
I09 Other rheumatic heart diseases	0.029	0.971	0.000
I06 Rheumatic aortic valve diseases	0.029	0.971	0.000
I95.9 Hypotension, unspecified	0.027	0.973	0.000
I27.9 Pulmonary heart disease, unspecified	0.027	0.973	0.000
I02 Rheumatic chorea	0.027	0.973	0.000
I01 Rheumatic fever with heart involvement	0.027	0.973	0.000
I00 Rheumatic fever without mention of heart involvement	0.027	0.973	0.000
I95.2 Hypotension due to drugs	0.027	0.973	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.026	0.973	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.026	0.973	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.026	0.973	0.000
I98.0 Cardiovascular syphilis	0.026	0.973	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.026	0.973	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.026	0.973	0.000
I97.1 Other functional disturbances following cardiac surgery	0.026	0.973	0.000
I97.0 Postcardiotomy syndrome	0.026	0.973	0.000
I05.9 Mitral valve disease, unspecified	0.026	0.974	0.000
I05.8 Other mitral valve diseases	0.025	0.975	0.000
I05.2 Mitral stenosis with insufficiency	0.025	0.975	0.000
I05.0 Mitral stenosis	0.025	0.975	0.000
I08.0 Disorders of both mitral and aortic valves	0.025	0.975	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.025	0.975	0.000
I28.8 Other specified diseases of pulmonary vessels	0.025	0.975	0.000
I28.1 Aneurysm of pulmonary artery	0.025	0.975	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.025	0.975	0.000
I72 Other aneurysm	0.024	0.976	0.000
I73.8 Other specified peripheral vascular diseases	0.024	0.976	0.000
I07 Rheumatic tricuspid valve diseases	0.023	0.976	0.000
I70 Atherosclerosis	0.024	0.976	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.023	0.977	0.000
O70.3 Fourth degree perineal laceration during delivery	0.000	0.977	0.023
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.023	0.977	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.022	0.978	0.000
I08.9 Multiple valve disease, unspecified	0.022	0.978	0.000
I08.8 Other multiple valve diseases	0.022	0.978	0.000
I78 Diseases of capillaries	0.021	0.978	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.979	0.021
I06.9 Rheumatic aortic valve disease, unspecified	0.021	0.979	0.000
I06.8 Other rheumatic aortic valve diseases	0.021	0.979	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.021	0.979	0.000
I06.1 Rheumatic aortic insufficiency	0.021	0.979	0.000
I06.0 Rheumatic aortic stenosis	0.021	0.979	0.000
I09.9 Rheumatic heart disease, unspecified	0.021	0.979	0.000
I09.8 Other specified rheumatic heart diseases	0.021	0.979	0.000
I09.2 Chronic rheumatic pericarditis	0.021	0.979	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.021	0.979	0.000
I09.0 Rheumatic myocarditis	0.021	0.979	0.000
I74 Arterial embolism and thrombosis	0.020	0.980	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.020	0.980	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.020	0.980	0.000
I01.8 Other acute rheumatic heart disease	0.020	0.980	0.000
I01.2 Acute rheumatic myocarditis	0.020	0.980	0.000
I01.1 Acute rheumatic endocarditis	0.020	0.980	0.000
I01.0 Acute rheumatic pericarditis	0.020	0.980	0.000
I02.9 Rheumatic chorea without heart involvement	0.020	0.980	0.000
I02.0 Rheumatic chorea with heart involvement	0.020	0.980	0.000
I77 Other disorders of arteries and arterioles	0.019	0.980	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.981	0.019
Z95 Presence of cardiac and vascular implants and grafts	0.019	0.981	0.000
I72.4 Aneurysm of artery of lower extremity	0.018	0.982	0.000
I70.0 Atherosclerosis of aorta	0.018	0.982	0.000
I72.8 Aneurysm of other specified arteries	0.018	0.982	0.000
I72.9 Aneurysm of unspecified site	0.017	0.982	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.017	0.982	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.017	0.982	0.000
I72.3 Aneurysm of iliac artery	0.017	0.982	0.000
I72.2 Aneurysm of renal artery	0.017	0.982	0.000
I72.1 Aneurysm of artery of upper extremity	0.017	0.982	0.000
I72.0 Aneurysm of carotid artery	0.017	0.982	0.000
I07.9 Tricuspid valve disease, unspecified	0.017	0.983	0.000
I07.8 Other tricuspid valve diseases	0.017	0.983	0.000
I07.2 Tricuspid stenosis with insufficiency	0.017	0.983	0.000
I07.0 Tricuspid stenosis	0.017	0.983	0.000
I70.9 Generalised and unspecified atherosclerosis	0.017	0.983	0.000
I70.8 Atherosclerosis of other arteries	0.017	0.983	0.000
I70.1 Atherosclerosis of renal artery	0.017	0.983	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.017	0.983	0.000
I77.6 Arteritis, unspecified	0.017	0.983	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.016	0.983	0.000
I79.1 Aortitis in diseases classified elsewhere	0.016	0.983	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.016	0.983	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.017	0.983	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.016	0.984	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.016	0.984	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.016	0.984	0.000
I78.9 Disease of capillaries, unspecified	0.015	0.984	0.000
I78.8 Other diseases of capillaries	0.015	0.984	0.000
I73.0 Raynaud's syndrome	0.015	0.985	0.000
I10-I15 Hypertensive diseases	0.015	0.985	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.015	0.985	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.014	0.985	0.000
I74.8 Embolism and thrombosis of other arteries	0.014	0.985	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.014	0.985	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.014	0.985	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.014	0.985	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.985	0.015
I77.5 Necrosis of artery	0.014	0.986	0.000
I77.4 Coeliac artery compression syndrome	0.014	0.986	0.000
I77.3 Arterial fibromuscular dysplasia	0.014	0.986	0.000
I77.2 Rupture of artery	0.014	0.986	0.000
I77.0 Arteriovenous fistula, acquired	0.014	0.986	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.014	0.986	0.000
Z95.1 Presence of aortocoronary bypass graft	0.014	0.986	0.000
I78.1 Naevus, nonneoplastic	0.013	0.986	0.000
I77.8 Other specified disorders of arteries and arterioles	0.013	0.987	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.013	0.987	0.000
I74.5 Embolism and thrombosis of iliac artery	0.013	0.987	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.013	0.987	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.012	0.987	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.012	0.987	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.012	0.987	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.012	0.987	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.012	0.987	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.012	0.987	0.000
Chapter VI Diseases of the nervous system	0.000	0.987	0.013
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.012	0.988	0.000
I77.1 Stricture of artery	0.012	0.988	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.012	0.988	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.988	0.012
I07.1 Tricuspid insufficiency	0.011	0.988	0.001
Z95.3 Presence of xenogenic heart valve	0.011	0.989	0.000
I13 Hypertensive heart and renal disease	0.011	0.989	0.000
I15 Secondary hypertension	0.011	0.989	0.000
I11 Hypertensive heart disease	0.011	0.989	0.000
Z95.0 Presence of cardiac pacemaker	0.011	0.989	0.000
G35 Multiple sclerosis	0.000	0.989	0.011
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.010	0.990	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.990	0.010
I77.9 Disorder of arteries and arterioles, unspecified	0.009	0.990	0.000
H35.3 Degeneration of macula and posterior pole	0.010	0.990	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.990	0.010
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.990	0.009
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.991	0.009
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.991	0.009
N43.3 Hydrocele, unspecified	0.000	0.991	0.009
Z95.2 Presence of prosthetic heart valve	0.009	0.991	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.991	0.009
I84.5 External haemorrhoids without complication	0.000	0.991	0.009
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.991	0.009
G70-G73 Diseases of myoneural junction and muscle	0.000	0.991	0.009
G36 Other acute disseminated demyelination	0.000	0.991	0.009
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.991	0.008
I71 Aortic aneurysm and dissection	0.007	0.991	0.001
I60-I69 Cerebrovascular diseases	0.003	0.992	0.005
I13.9 Hypertensive heart and renal disease, unspecified	0.008	0.992	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.008	0.992	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.008	0.992	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.008	0.992	0.000
I15.9 Seconday hypertension, unspecified	0.008	0.992	0.000
I15.8 Other secondary hypertension	0.008	0.992	0.000
I15.2 Hypertension secondary to endocrine disorders	0.008	0.992	0.000
I15.0 Renovascular hypertension	0.008	0.992	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.008	0.992	0.000
I15.1 Hypertension secondary to other renal disorders	0.008	0.992	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.008	0.992	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
I12 Hypertensive renal disease	0.008	0.992	0.000
K57 Diverticular disease of intestine	0.000	0.992	0.008
G12 Spinal muscular atrophy and related syndromes	0.000	0.992	0.008
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.992	0.008
Z95.4 Presence of other heart-valve replacement	0.007	0.992	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.992	0.007
G83 Other paralytic syndromes	0.000	0.992	0.007
I67.9 Cerebrovascular disease, unspecified	0.000	0.993	0.007
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.993	0.007
I67 Other cerebrovascular diseases	0.001	0.993	0.007
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.007	0.993	0.000
K58 Irritable bowel syndrome	0.000	0.993	0.007
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.993	0.007
G37.5 Concentric sclerosis [Balo]	0.000	0.993	0.007
G37.4 Subacute necrotising myelitis	0.000	0.993	0.007
G37.2 Central pontine myelinolysis	0.000	0.993	0.007
G37.1 Central demyelination of corpus callosum	0.000	0.993	0.007
G37.0 Diffuse sclerosis	0.000	0.993	0.007
G62 Other polyneuropathies	0.000	0.993	0.007
G30 Alzheimer's disease	0.000	0.993	0.007
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.007	0.993	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.993	0.007
G14 Postpolio syndrome	0.000	0.993	0.007
G10 Huntington's disease	0.000	0.993	0.007
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.993	0.007
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.993	0.007
G64 Other disorders of peripheral nervous system	0.000	0.993	0.007
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.993	0.007
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.993	0.007
G03 Meningitis due to other and unspecified causes	0.000	0.993	0.007
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.993	0.007
G00 Bacterial meningitis, not elsewhere classified	0.000	0.993	0.007
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.993	0.007
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.993	0.007
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.993	0.007
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.993	0.007
G80 Infantile cerebral palsy	0.000	0.993	0.007
I67.8 Other specified cerebrovascular diseases	0.000	0.993	0.007
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.993	0.007
G60 Hereditary and idiopathic neuropathy	0.000	0.993	0.007
I61 Intracerebral haemorrhage	0.002	0.993	0.005
G72 Other myopathies	0.000	0.993	0.006
G11 Hereditary ataxia	0.000	0.993	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.006
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.993	0.006
G61 Inflammatory polyneuropathy	0.000	0.993	0.006
G36.9 Acute disseminated demyelination, unspecified	0.000	0.993	0.006
G36.8 Other specified acute disseminated demyelination	0.000	0.993	0.006
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.993	0.006
G36.0 Neuromyelitis optica [Devic]	0.000	0.993	0.006
G81 Hemiplegia	0.000	0.993	0.006
G70 Myasthenia gravis and other myoneural disorders	0.000	0.994	0.006
G12.2 Motor neuron disease	0.000	0.994	0.006
I71.8 Aortic aneurysm of unspecified site, ruptured	0.005	0.994	0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.005	0.994	0.001
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.005	0.994	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.005	0.994	0.001
I71.1 Thoracic aortic aneurysm, ruptured	0.005	0.994	0.001
G83.4 Cauda equina syndrome	0.000	0.994	0.006
G62.8 Other specified polyneuropathies	0.000	0.994	0.006
I86 Varicose veins of other sites	0.006	0.994	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.002	0.994	0.004
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.002	0.994	0.004
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.994	0.006
G63.2 Diabetic polyneuropathy	0.000	0.994	0.006
G71 Primary disorders of muscles	0.000	0.994	0.006
G31.8 Other specified degenerative diseases of nervous system	0.000	0.994	0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.005	0.994	0.001
G31.2 Degeneration of nervous system due to alcohol	0.000	0.994	0.006
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
G31.0 Circumscribed brain atrophy	0.000	0.994	0.006
I62 Other nontraumatic intracranial haemorrhage	0.002	0.994	0.004
I67.2 Cerebral atherosclerosis	0.000	0.994	0.006
I69 Sequelae of cerebrovascular disease	0.001	0.994	0.005
G82 Paraplegia and tetraplegia	0.000	0.994	0.006
I63 Cerebral infarction	0.001	0.994	0.005
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.994	0.006
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.994	0.006
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.994	0.006
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.994	0.006
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.002	0.994	0.004
G20-G26 Extrapyramidal and movement disorders	0.000	0.994	0.006
G12.9 Spinal muscular atrophy, unspecified	0.000	0.994	0.006
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.994	0.006
G12.1 Other inherited spinal muscular atrophy	0.000	0.994	0.006
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.994	0.006
I85 Oesophageal varices	0.006	0.994	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.994	0.006
O60-O75 Complications of labour and delivery	0.000	0.994	0.006
I87 Other disorders of veins	0.006	0.994	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.994	0.005
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.994	0.005
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.994	0.005
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.994	0.005
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.994	0.005
G63.1 Polyneuropathy in neoplastic disease	0.000	0.994	0.005
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.005
G83.9 Paralytic syndrome, unspecified	0.000	0.994	0.005
G83.8 Other specified paralytic syndromes	0.000	0.994	0.005
G83.5 Locked-in syndrome	0.000	0.994	0.005
G83.3 Monoplegia, unspecified	0.000	0.994	0.005
G83.2 Monoplegia of upper limb	0.000	0.994	0.005
G83.1 Monoplegia of lower limb	0.000	0.994	0.005
G83.0 Diplegia of upper limbs	0.000	0.994	0.005
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.994	0.005
I71.0 Dissection of aorta [any part]	0.004	0.994	0.001
I86.1 Scrotal varices	0.005	0.994	0.000
H00.1 Chalazion	0.006	0.994	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.001	0.994	0.005
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.001	0.994	0.005
I67.5 Moyamoya disease	0.001	0.994	0.005
I67.4 Hypertensive encephalopathy	0.001	0.994	0.005
I67.3 Progressive vascular leukoencephalopathy	0.001	0.994	0.005
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.994	0.005
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.994	0.005
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.994	0.005
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.994	0.005
C85.1 B-cell lymphoma, unspecified	0.000	0.995	0.005
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.995	0.005
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.995	0.005
G62.2 Polyneuropathy due to other toxic agents	0.000	0.995	0.005
G62.1 Alcoholic polyneuropathy	0.000	0.995	0.005
G62.0 Drug-induced polyneuropathy	0.000	0.995	0.005
G30.8 Other Alzheimer's disease	0.000	0.995	0.005
G30.1 Alzheimer's disease with late onset	0.000	0.995	0.005
G30.0 Alzheimer's disease with early onset	0.000	0.995	0.005
I88 Nonspecific lymphadenitis	0.005	0.995	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.995	0.005
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.995	0.005
G04.1 Tropical spastic paraplegia	0.000	0.995	0.005
G04.0 Acute disseminated encephalitis	0.000	0.995	0.005
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.000	0.995	0.005
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.000	0.995	0.005
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.000	0.995	0.005
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.000	0.995	0.005
I60 Subarachnoid haemorrhage	0.003	0.995	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.001	0.995	0.004
G00.9 Bacterial meningitis, unspecified	0.000	0.995	0.005
G00.8 Other bacterial meningitis	0.000	0.995	0.005
G00.3 Staphylococcal meningitis	0.000	0.995	0.005
G00.2 Streptococcal meningitis	0.000	0.995	0.005
G00.1 Pneumococcal meningitis	0.000	0.995	0.005
G00.0 Haemophilus meningitis	0.000	0.995	0.005
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
G02.1 Meningitis in mycoses	0.000	0.995	0.005
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.995	0.005
G03.9 Meningitis, unspecified	0.000	0.995	0.005
G03.8 Meningitis due to other specified causes	0.000	0.995	0.005
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.995	0.005
G03.1 Chronic meningitis	0.000	0.995	0.005
G03.0 Nonpyogenic meningitis	0.000	0.995	0.005
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.995	0.005
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.995	0.005
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.995	0.005
G06.2 Extradural and subdural abscess, unspecified	0.000	0.995	0.005
G06.1 Intraspinal abscess and granuloma	0.000	0.995	0.005
G06.0 Intracranial abscess and granuloma	0.000	0.995	0.005
G80.9 Infantile cerebral palsy, unspecified	0.000	0.995	0.005
G30.9 Alzheimer's disease, unspecified	0.000	0.995	0.005
G80.8 Other infantile cerebral palsy	0.000	0.995	0.005
G80.4 Ataxic cerebral palsy	0.000	0.995	0.005
G80.3 Dyskinetic cerebral palsy	0.000	0.995	0.005
G80.2 Infantile hemiplegia	0.000	0.995	0.005
G80.1 Spastic diplegia	0.000	0.995	0.005
G80.0 Spastic cerebral palsy	0.000	0.995	0.005
G50-G59 Nerve, nerve root and plexus disorders	0.000	0.995	0.005
G72.9 Myopathy, unspecified	0.000	0.995	0.005
I67.0 Dissection of cerebral arteries, nonruptured	0.001	0.995	0.005
I86.8 Varicose veins of other specified sites	0.005	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.995	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.995	0.005
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.995	0.005
G60.3 Idiopathic progressive neuropathy	0.000	0.995	0.005
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.995	0.005
G60.1 Refsum's disease	0.000	0.995	0.005
G72.8 Other specified myopathies	0.000	0.995	0.005
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.995	0.005
G72.3 Periodic paralysis	0.000	0.995	0.005
G72.2 Myopathy due to other toxic agents	0.000	0.995	0.005
G72.1 Alcoholic myopathy	0.000	0.995	0.005
G72.0 Drug-induced myopathy	0.000	0.995	0.005
I61.8 Other intracerebral haemorrhage	0.001	0.995	0.004
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.995	0.004
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.995	0.004
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.995	0.004
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.995	0.004
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.995	0.004
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.995	0.004
G11.8 Other hereditary ataxias	0.000	0.995	0.005
G11.4 Hereditary spastic paraplegia	0.000	0.995	0.005
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.995	0.005
G11.2 Late-onset cerebellar ataxia	0.000	0.995	0.005
G11.1 Early-onset cerebellar ataxia	0.000	0.995	0.005
G11.0 Congenital nonprogressive ataxia	0.000	0.995	0.005
I87.2 Venous insufficiency (chronic) (peripheral)	0.005	0.995	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.995	0.005
G61.1 Serum neuropathy	0.000	0.995	0.005
G73.7 Myopathy other diseases classified elsewhere	0.000	0.995	0.005
G73.6 Myopathy in metabolic diseases	0.000	0.995	0.005
G73.5 Myopathy in endocrine diseases	0.000	0.995	0.005
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations