TreeWAS – Variant ID: rs1395479

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S06 Intracranial injury	0.415	0.585	0.000
S06.5 Traumatic subdural haemorrhage	0.401	0.599	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.392	0.608	0.000
S06.3 Focal brain injury	0.389	0.610	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.387	0.613	0.000
S06.9 Intracranial injury, unspecified	0.371	0.629	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.371	0.629	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.367	0.633	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.340	0.660	0.000
S06.0 Concussion	0.338	0.662	0.000
S06.4 Epidural haemorrhage	0.337	0.663	0.000
S06.8 Other intracranial injuries	0.336	0.664	0.000
S06.1 Traumatic cerebral oedema	0.331	0.669	0.000
S06.2 Diffuse brain injury	0.311	0.689	0.000
S06.7 Intracranial injury with prolonged coma	0.298	0.702	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.288	0.712	0.000
S06.00 Concussion (without open intracranial wound)	0.282	0.718	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.281	0.719	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.279	0.721	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.279	0.721	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.277	0.722	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.270	0.729	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.266	0.734	0.000
S00-S09 Injuries to the head	0.254	0.746	0.000
S06.01 Concussion (with open intracranial wound)	0.242	0.757	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.242	0.758	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.241	0.759	0.000
S02 Fracture of skull and facial bones	0.239	0.761	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.237	0.762	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.236	0.764	0.000
S02.1 Fracture of base of skull	0.229	0.771	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.223	0.777	0.000
S02.10 Fracture of base of skull (closed)	0.223	0.777	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.214	0.786	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.214	0.786	0.000
S00 Superficial injury of head	0.208	0.792	0.000
S08 Traumatic amputation of part of head	0.201	0.799	0.000
S02.5 Fracture of tooth	0.187	0.813	0.000
S02.3 Fracture of orbital floor	0.184	0.816	0.000
S07 Crushing injury of head	0.182	0.818	0.000
S04 Injury of cranial nerves	0.182	0.818	0.000
S00.3 Superficial injury of nose	0.182	0.818	0.000
S02.6 Fracture of mandible	0.182	0.818	0.000
S02.7 Multiple fractures involving skull and facial bones	0.180	0.819	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.179	0.820	0.000
S02.0 Fracture of vault of skull	0.178	0.822	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.172	0.828	0.000
S00.0 Superficial injury of scalp	0.167	0.833	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.167	0.833	0.000
S02.11 Fracture of base of skull (open)	0.166	0.834	0.000
S02.2 Fracture of nasal bones	0.164	0.835	0.000
S08.1 Traumatic amputation of ear	0.163	0.837	0.000
S00.4 Superficial injury of ear	0.162	0.838	0.000
S02.8 Fractures of other skull and facial bones	0.160	0.840	0.000
S00.5 Superficial injury of lip and oral cavity	0.155	0.845	0.000
S01 Open wound of head	0.152	0.848	0.000
S02.50 Fracture of tooth (closed)	0.150	0.850	0.000
S02.30 Fracture of orbital floor (closed)	0.145	0.855	0.000
S08.9 Traumatic amputation of unspecified part of head	0.144	0.856	0.000
S08.8 Traumatic amputation of other parts of head	0.144	0.856	0.000
S08.0 Avulsion of scalp	0.144	0.856	0.000
S05 Injury of eye and orbit	0.141	0.859	0.000
S02.60 Fracture of mandible (closed)	0.140	0.859	0.000
S00.1 Contusion of eyelid and periocular area	0.139	0.861	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.139	0.861	0.000
S01.8 Open wound of other parts of head	0.136	0.864	0.000
S02.51 Fracture of tooth (open)	0.134	0.865	0.000
S02.00 Fracture of vault of skull (closed)	0.134	0.866	0.000
S03.0 Dislocation of jaw	0.134	0.866	0.000
S02.31 Fracture of orbital floor (open)	0.132	0.868	0.000
S00.7 Multiple superficial injuries of head	0.131	0.869	0.000
S04.9 Injury of unspecified cranial nerve	0.131	0.869	0.000
S04.8 Injury of other cranial nerves	0.131	0.869	0.000
S04.7 Injury of accessory nerve	0.131	0.869	0.000
S04.6 Injury of acoustic nerve	0.131	0.869	0.000
S04.5 Injury of facial nerve	0.131	0.869	0.000
S04.4 Injury of abducent nerve	0.131	0.869	0.000
S04.3 Injury of trigeminal nerve	0.131	0.869	0.000
S04.2 Injury of trochlear nerve	0.131	0.869	0.000
S04.1 Injury of oculomotor nerve	0.131	0.869	0.000
S04.0 Injury of optic nerve and pathways	0.131	0.869	0.000
S07.9 Crushing injury of head, part unspecified	0.131	0.869	0.000
S07.8 Crushing injury of other parts of head	0.131	0.869	0.000
S07.1 Crushing injury of skull	0.131	0.869	0.000
S07.0 Crushing injury of face	0.131	0.869	0.000
S02.61 Fracture of mandible (open)	0.130	0.870	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.129	0.870	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.129	0.871	0.000
S03.4 Sprain and strain of jaw	0.129	0.871	0.000
S03.3 Dislocation of other and unspecified parts of head	0.129	0.871	0.000
S03.1 Dislocation of septal cartilage of nose	0.129	0.871	0.000
S02.01 Fracture of vault of skull (open)	0.127	0.872	0.000
S01.0 Open wound of scalp	0.125	0.875	0.000
S01.9 Open wound of head, part unspecified	0.121	0.879	0.000
S03.2 Dislocation of tooth	0.120	0.879	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.120	0.880	0.000
S02.21 Fracture of nasal bones (open)	0.118	0.882	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.117	0.883	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.116	0.884	0.000
S00.9 Superficial injury of head, part unspecified	0.116	0.884	0.000
S02.81 Fractures of other skull and facial bones (open)	0.115	0.885	0.000
S01.4 Open wound of cheek and temporomandibular area	0.115	0.885	0.000
S02.4 Fracture of malar and maxillary bones	0.114	0.885	0.000
S00.8 Superficial injury of other parts of head	0.113	0.887	0.000
S09 Other and unspecified injuries of head	0.112	0.887	0.000
S02.20 Fracture of nasal bones (closed)	0.111	0.889	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.109	0.891	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.108	0.892	0.000
S01.7 Multiple open wounds of head	0.107	0.893	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.103	0.896	0.000
S05.7 Avulsion of eye	0.101	0.899	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.101	0.899	0.000
S05.9 Injury of eye and orbit, part unspecified	0.099	0.901	0.000
S05.8 Other injuries of eye and orbit	0.097	0.903	0.000
S01.5 Open wound of lip and oral cavity	0.096	0.904	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.090	0.910	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.082	0.918	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.082	0.918	0.000
S09.7 Multiple injuries of head	0.081	0.919	0.000
S09.2 Traumatic rupture of ear drum	0.081	0.919	0.000
S09.1 Injury of muscle and tendon of head	0.081	0.919	0.000
S01.2 Open wound of nose	0.081	0.919	0.000
S09.8 Other specified injuries of head	0.077	0.923	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.070	0.930	0.000
S01.3 Open wound of ear	0.069	0.931	0.000
S05.1 Contusion of eyeball and orbital tissues	0.053	0.946	0.000
S01.1 Open wound of eyelid and periocular area	0.046	0.954	0.000
S09.9 Unspecified injury of head	0.045	0.955	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.025	0.975	0.000
Z51.0 Radiotherapy session	0.000	0.988	0.012
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.011	0.989	0.000
C18.7 Sigmoid colon	0.010	0.990	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.009	0.991	0.000
H53.9 Visual disturbance, unspecified	0.009	0.991	0.000
T42.0 Hydantoin derivatives	0.009	0.991	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.008	0.992	0.000
T42.3 Barbiturates	0.007	0.993	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.007	0.993	0.000
T39.0 Salicylates	0.007	0.993	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.007	0.993	0.000
H53.4 Visual field defects	0.007	0.993	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.993	0.000
I34.0 Mitral (valve) insufficiency	0.007	0.993	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
H53 Visual disturbances	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
H53.8 Other visual disturbances	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
I34.1 Mitral (valve) prolapse	0.006	0.994	0.000
T42.4 Benzodiazepines	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.005	0.994	0.000
T39.2 Pyrazolone derivatives	0.005	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.994	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
D22.4 Melanocytic naevi of scalp and neck	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
I34 Nonrheumatic mitral valve disorders	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
T42.1 Iminostilbenes	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.005	0.995	0.000
H53.6 Night blindness	0.005	0.995	0.000
H53.5 Colour vision deficiencies	0.005	0.995	0.000
H53.3 Other disorders of binocular vision	0.005	0.995	0.000
I84.8 Unspecified haemorrhoids with other complications	0.000	0.995	0.005
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.995	0.000
T47.7 Emetics	0.004	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.995	0.000
T47.5 Digestants	0.004	0.995	0.000
T47.4 Other laxatives	0.004	0.995	0.000
T47.3 Saline and osmotic laxatives	0.004	0.995	0.000
T47.2 Stimulant laxatives	0.004	0.995	0.000
T48.5 Anti-common-cold drugs	0.004	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.004	0.996	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.004	0.996	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.003	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.996	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.996	0.000
T40.8 Lysergide [LSD]	0.003	0.996	0.000
T40.7 Cannabis (derivatives)	0.003	0.996	0.000
T40.5 Cocaine	0.003	0.996	0.000
T40.3 Methadone	0.003	0.996	0.000
T40.1 Heroin	0.003	0.996	0.000
T40.0 Opium	0.003	0.996	0.000
H35.8 Other specified retinal disorders	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
N71 Inflammatory disease of uterus, except cervix	0.003	0.997	0.000
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
H53.0 Amblyopia ex anopsia	0.003	0.997	0.000
N71.1 Chronic inflammatory disease of uterus	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
S19.9 Unspecified injury of neck	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
H35.9 Retinal disorder, unspecified	0.003	0.997	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.997	0.003
K37 Unspecified appendicitis	0.000	0.997	0.003
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.997	0.003
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
T70.3 Caisson disease [decompression sickness]	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
H53.1 Subjective visual disturbances	0.003	0.997	0.000
N71.0 Acute inflammatory disease of uterus	0.003	0.997	0.000
S10-S19 Injuries to the neck	0.003	0.997	0.000
T25.3 Burn of third degree of ankle and foot	0.003	0.997	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
Z94.7 Corneal transplant status	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.997	0.001
R60.0 Localised oedema	0.000	0.997	0.003
T21 Burn and corrosion of trunk	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
I73.8 Other specified peripheral vascular diseases	0.003	0.997	0.000
S12 Fracture of neck	0.003	0.997	0.000
H35.5 Hereditary retinal dystrophy	0.003	0.997	0.000
H35 Other retinal disorders	0.003	0.997	0.000
T36.0 Penicillins	0.002	0.997	0.001
T78.3 Angioneurotic oedema	0.003	0.997	0.000
T21.2 Burn of second degree of trunk	0.002	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.997	0.000
T46.7 Peripheral vasodilators	0.002	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.997	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
S10 Superficial injury of neck	0.002	0.997	0.000
S19.7 Multiple injuries of neck	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
S19.8 Other specified injuries of neck	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
T00-T07 Injuries involving multiple body regions	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
D35.1 Parathyroid gland	0.000	0.998	0.002
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.002	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.002	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.002	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.001
T45.4 Iron and its compounds	0.002	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.001
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.001
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T66 Unspecified effects of radiation	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
T33-T35 Frostbite	0.002	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T25.7 Corrosion of third degree of ankle and foot	0.002	0.998	0.000
T25.6 Corrosion of second degree of ankle and foot	0.002	0.998	0.000
T25.5 Corrosion of first degree of ankle and foot	0.002	0.998	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.002	0.998	0.000
T25.1 Burn of first degree of ankle and foot	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.002	0.998	0.000
T70.8 Other effects of air pressure and water pressure	0.002	0.998	0.000
T70.4 Effects of high-pressure fluids	0.002	0.998	0.000
T70.2 Other and unspecified effects of high altitude	0.002	0.998	0.000
T70.1 Sinus barotrauma	0.002	0.998	0.000
T70.0 Otitic barotrauma	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.002	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.002	0.998	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.998	0.002
H35.4 Peripheral retinal degeneration	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
H35.1 Retinopathy of prematurity	0.002	0.998	0.000
T75 Effects of other external causes	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
D18.0 Haemangioma, any site	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T02 Fractures involving multiple body regions	0.002	0.998	0.000
T74 Maltreatment syndromes	0.002	0.998	0.000
T73 Effects of other deprivation	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
T09 Other injuries of spine and trunk, level unspecified	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.002	0.998	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.002	0.998	0.000
S10.0 Contusion of throat	0.002	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
T09.3 Injury of spinal cord, level unspecified	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.002	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.002	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.002	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.002	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
T01 Open wounds involving multiple body regions	0.002	0.998	0.000
T11 Other injuries of upper limb, level unspecified	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
H35.6 Retinal haemorrhage	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.002	0.998	0.000
T25.2 Burn of second degree of ankle and foot	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
D31.0 Conjunctiva	0.000	0.998	0.002
T75.1 Drowning and nonfatal submersion	0.002	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.002	0.998	0.000
H35.7 Separation of retinal layers	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.002	0.998	0.000
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.002	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.002	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.002	0.998	0.000
S15.3 Injury of internal jugular vein	0.002	0.998	0.000
S15.2 Injury of external jugular vein	0.002	0.998	0.000
S15.1 Injury of vertebral artery	0.002	0.998	0.000
S15.0 Injury of carotid artery	0.002	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.002	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.002	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.998	0.001
Q66 Congenital deformities of feet	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.002	0.998	0.000
T23.6 Corrosion of second degree of wrist and hand	0.002	0.998	0.000
T23.5 Corrosion of first degree of wrist and hand	0.002	0.998	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.002	0.998	0.000
T05 Traumatic amputations involving multiple body regions	0.002	0.998	0.000
T04 Crushing injuries involving multiple body regions	0.002	0.998	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.002	0.998	0.000
T07 Unspecified multiple injuries	0.002	0.998	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.002	0.998	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.002	0.998	0.000
T12 Fracture of lower limb, level unspecified	0.002	0.998	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.002	0.998	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.002	0.998	0.000
T10 Fracture of upper limb, level unspecified	0.002	0.998	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.002	0.998	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.002	0.998	0.000
T08 Fracture of spine, level unspecified	0.002	0.998	0.000
T71 Asphyxiation	0.002	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations