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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1397230
log Bayes Factor = 10.2387
Chromosome 3   position 161,797,310  (GRCh37) Explore rs1397230 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
F30-F39 Mood [affective] disorders
0.999 0.001 0.000
# Top node
0.998 0.002 0.000
T43.2 Other and unspecified antidepressants
0.997 0.003 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.989 0.011 0.000
M05 Seropositive rheumatoid arthritis
0.989 0.011 0.000
F33 Recurrent depressive disorder
0.985 0.015 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.985 0.015 0.000
F20 Schizophrenia
0.982 0.018 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.982 0.018 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.976 0.024 0.000
M80-M85 Disorders of bone density and structure
0.972 0.028 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.969 0.031 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.969 0.031 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.965 0.035 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.964 0.036 0.000
M85 Other disorders of bone density and structure
0.963 0.037 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.962 0.038 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.959 0.041 0.000
T51 Toxic effect of alcohol
0.954 0.046 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.954 0.046 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.954 0.046 0.000
M85.8 Other specified disorders of bone density and structure
0.952 0.048 0.000
X41.9 Unspecified place
0.951 0.049 0.000
X60-X84 Intentional self-harm
0.947 0.053 0.000
T51.0 Ethanol
0.942 0.058 0.000
S50-S59 Injuries to the elbow and forearm
0.940 0.060 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.930 0.070 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.928 0.072 0.000
F20.0 Paranoid schizophrenia
0.927 0.073 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.927 0.073 0.000
S51 Open wound of forearm
0.921 0.079 0.000
F33.9 Recurrent depressive disorder, unspecified
0.921 0.079 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.918 0.082 0.000
M10 Gout
0.916 0.084 0.000
F20.9 Schizophrenia, unspecified
0.914 0.086 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.913 0.087 0.000
F31 Bipolar affective disorder
0.913 0.087 0.000
M06.3 Rheumatoid nodule
0.908 0.092 0.000
M86-M90 Other osteopathies
0.906 0.094 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.906 0.094 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.903 0.097 0.000
M45-M49 Spondylopathies
0.903 0.097 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.902 0.098 0.000
F32 Depressive episode
0.902 0.098 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.901 0.099 0.000
X78 Intentional self-harm by sharp object
0.901 0.099 0.000
S51.9 Open wound of forearm, part unspecified
0.891 0.109 0.000
F23 Acute and transient psychotic disorders
0.888 0.112 0.000
F60-F69 Disorders of adult personality and behaviour
0.885 0.115 0.000
M45 Ankylosing spondylitis
0.882 0.118 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.876 0.124 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.870 0.130 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.869 0.131 0.000
X78.0 Home
0.868 0.132 0.000
S10-S19 Injuries to the neck
0.866 0.134 0.000
F25 Schizoaffective disorders
0.862 0.138 0.000
T91 Sequelae of injuries of neck and trunk
0.862 0.138 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.861 0.139 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.853 0.147 0.000
M70-M79 Other soft tissue disorders
0.851 0.149 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.849 0.151 0.000
S32 Fracture of lumbar spine and pelvis
0.846 0.154 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.846 0.154 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.845 0.155 0.000
F39 Unspecified mood [affective] disorder
0.844 0.156 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
M10.9 Gout, unspecified
0.836 0.164 0.000
V70-V79 Bus occupant injured in transport accident
0.835 0.165 0.000
S51.8 Open wound of other parts of forearm
0.834 0.166 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.833 0.167 0.000
S56 Injury of muscle and tendon at forearm level
0.832 0.168 0.000
S70-S79 Injuries to the hip and thigh
0.832 0.168 0.000
F70-F79 Mental retardation
0.831 0.169 0.000
Y00-Y09 Assault
0.831 0.169 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.827 0.173 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.827 0.173 0.000
T66-T78 Other and unspecified effects of external causes
0.827 0.173 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.826 0.174 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.826 0.174 0.000
M86 Osteomyelitis
0.826 0.174 0.000
V90-V94 Water transport accidents
0.825 0.175 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.819 0.181 0.000
T58 Toxic effect of carbon monoxide
0.817 0.183 0.000
F32.1 Moderate depressive episode
0.816 0.184 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.815 0.185 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.815 0.185 0.000
Y60.0 During surgical operation
0.815 0.185 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.814 0.186 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.812 0.188 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.812 0.188 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.804 0.196 0.000
M06.8 Other specified rheumatoid arthritis
0.804 0.196 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.802 0.198 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.802 0.198 0.000
V01-V09 Pedestrian injured in transport accident
0.798 0.202 0.000
M07 Psoriatic and enteropathic arthropathies
0.798 0.202 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.797 0.203 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.797 0.203 0.000
M85.6 Other cyst of bone
0.795 0.205 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.793 0.207 0.000
Q60-Q64 Congenital malformations of the urinary system
0.790 0.210 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.790 0.210 0.000
T91.1 Sequelae of fracture of spine
0.788 0.212 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.786 0.214 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.783 0.217 0.000
F30 Manic episode
0.783 0.217 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.783 0.217 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.782 0.218 0.000
M06.34 Rheumatoid nodule (Hand)
0.778 0.222 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.778 0.222 0.000
M06.0 Seronegative rheumatoid arthritis
0.777 0.223 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.777 0.223 0.000
F29 Unspecified nonorganic psychosis
0.777 0.223 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.776 0.224 0.000
S72 Fracture of femur
0.776 0.224 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.775 0.225 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.774 0.226 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.774 0.226 0.000
M82 Osteoporosis in diseases classified elsewhere
0.774 0.226 0.000
S80-S89 Injuries to the knee and lower leg
0.772 0.228 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.771 0.229 0.000
F20.5 Residual schizophrenia
0.771 0.229 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.768 0.232 0.000
Y89 Sequelae of other external causes
0.768 0.232 0.000
T91.3 Sequelae of injury of spinal cord
0.768 0.232 0.000
F31.7 Bipolar affective disorder, currently in remission
0.767 0.233 0.000
M12 Other specific arthropathies
0.764 0.236 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.763 0.237 0.000
S36 Injury of intra-abdominal organs
0.762 0.238 0.000
F31.9 Bipolar affective disorder, unspecified
0.762 0.238 0.000
X45 Accidental poisoning by and exposure to alcohol
0.762 0.238 0.000
Y65 Other misadventures during surgical and medical care
0.761 0.239 0.000
Y66 Nonadministration of surgical and medical care
0.759 0.241 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.758 0.242 0.000
F43 Reaction to severe stress, and adjustment disorders
0.758 0.242 0.000
M79.0 Rheumatism, unspecified
0.757 0.243 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
M79.2 Neuralgia and neuritis, unspecified
0.756 0.244 0.000
F34 Persistent mood [affective] disorders
0.756 0.244 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.755 0.245 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.754 0.246 0.000
T45.5 Anticoagulants
0.754 0.246 0.000
X50-X57 Overexertion, travel and privation
0.752 0.248 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.751 0.249 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.750 0.249 0.000
F02 Dementia in other diseases classified elsewhere
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.750 0.250 0.000
W75-W84 Other accidental threats to breathing
0.747 0.253 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.745 0.255 0.000
S31 Open wound of abdomen, lower back and pelvis
0.745 0.255 0.000
F69 Unspecified disorder of adult personality and behaviour
0.744 0.255 0.000
M79.6 Pain in limb
0.744 0.256 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.743 0.257 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.743 0.257 0.000
F03 Unspecified dementia
0.742 0.258 0.000
S54 Injury of nerves at forearm level
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.734 0.266 0.000
S32.0 Fracture of lumbar vertebra
0.733 0.267 0.000
F60 Specific personality disorders
0.732 0.267 0.000
M87 Osteonecrosis
0.732 0.268 0.000
Y00 Assault by blunt object
0.730 0.270 0.000
X00-X09 Exposure to smoke, fire and flames
0.728 0.272 0.000
F25.1 Schizoaffective disorder, depressive type
0.727 0.273 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.726 0.274 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.726 0.274 0.000
T50.4 Drugs affecting uric acid metabolism
0.725 0.274 0.000
M14 Arthropathies in other diseases classified elsewhere
0.725 0.275 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.725 0.275 0.000
M86.9 Osteomyelitis, unspecified
0.725 0.275 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.724 0.275 0.000
S11 Open wound of neck
0.724 0.276 0.000
S32.4 Fracture of acetabulum
0.724 0.276 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.723 0.277 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.723 0.277 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.723 0.277 0.000
V95-V97 Air and space transport accidents
0.721 0.279 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.721 0.279 0.000
M10.0 Idiopathic gout
0.720 0.280 0.000
Y89.9 Sequelae of unspecified external cause
0.720 0.280 0.000
V78 Bus occupant injured in noncollision transport accident
0.720 0.280 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.720 0.280 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.282 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
T43.9 Psychotropic drug, unspecified
0.717 0.283 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.717 0.283 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.716 0.284 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.715 0.285 0.000
F28 Other nonorganic psychotic disorders
0.714 0.286 0.000
F24 Induced delusional disorder
0.714 0.286 0.000
F21 Schizotypal disorder
0.714 0.286 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.714 0.286 0.000
X42.2 School, other institution and public administrative area
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.713 0.287 0.000
F25.9 Schizoaffective disorder, unspecified
0.712 0.288 0.000
M83 Adult osteomalacia
0.712 0.288 0.000
F79 Unspecified mental retardation
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
T54 Toxic effect of corrosive substances
0.710 0.290 0.000
F41 Other anxiety disorders
0.710 0.290 0.000
M05.8 Other seropositive rheumatoid arthritis
0.709 0.291 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.709 0.291 0.000
M05.2 Rheumatoid vasculitis
0.709 0.291 0.000
M05.1 Rheumatoid lung disease
0.709 0.291 0.000
M05.0 Felty's syndrome
0.709 0.291 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
S72.2 Subtrochanteric fracture
0.708 0.292 0.000
F33.8 Other recurrent depressive disorders
0.706 0.294 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.706 0.294 0.000
X48 Accidental poisoning by and exposure to pesticides
0.706 0.294 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.706 0.294 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.706 0.294 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.706 0.294 0.000
F20.8 Other schizophrenia
0.704 0.296 0.000
F20.6 Simple schizophrenia
0.704 0.296 0.000
F20.4 Postschizophrenic depression
0.704 0.296 0.000
F20.3 Undifferentiated schizophrenia
0.704 0.296 0.000
F20.2 Catatonic schizophrenia
0.704 0.296 0.000
F20.1 Hebephrenic schizophrenia
0.704 0.296 0.000
S56.5 Injury of other extensor muscle and tendon at forearm level
0.704 0.296 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.704 0.296 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.704 0.296 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.704 0.296 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.704 0.296 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.704 0.296 0.000
V93 Accident on board watercraft without accident to watercraft, not causing drowning and submersion
0.702 0.297 0.000
M85.2 Hyperostosis of skull
0.702 0.298 0.000
T18 Foreign body in alimentary tract
0.702 0.298 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.700 0.300 0.000
T62 Toxic effect of other noxious substances eaten as food
0.700 0.300 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.700 0.300 0.000
T60 Toxic effect of pesticides
0.700 0.300 0.000
T57 Toxic effect of other inorganic substances
0.700 0.300 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.700 0.300 0.000
T52 Toxic effect of organic solvents
0.700 0.300 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.700 0.300 0.000
T55 Toxic effect of soaps and detergents
0.700 0.300 0.000
Q61 Cystic kidney disease
0.700 0.300 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.699 0.301 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.699 0.301 0.000
S19 Other and unspecified injuries of neck
0.699 0.301 0.000
M10.99 Gout, unspecified (Site unspecified)
0.699 0.301 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.695 0.305 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
M90 Osteopathies in diseases classified elsewhere
0.694 0.306 0.000
T65 Toxic effect of other and unspecified substances
0.693 0.306 0.000
M91-M94 Chondropathies
0.693 0.307 0.000
M85.0 Fibrous dysplasia (monostotic)
0.692 0.308 0.000
X41.0 Home
0.692 0.308 0.000
X41.8 Other specified place
0.692 0.308 0.000
X41.7 Farm
0.692 0.308 0.000
X41.6 Industrial and construction area
0.692 0.308 0.000
X41.5 Trade and service area
0.692 0.308 0.000
X41.4 Street and highway
0.692 0.308 0.000
X41.3 Sports and athletics area
0.692 0.308 0.000
X41.2 School, other institution and public administrative area
0.692 0.308 0.000
X41.1 Residential institution
0.692 0.308 0.000
T39.4 Antirheumatics, not elsewhere classified
0.691 0.309 0.000
T39.2 Pyrazolone derivatives
0.691 0.309 0.000
S51.7 Multiple open wounds of forearm
0.691 0.309 0.000
M85.5 Aneurysmal bone cyst
0.691 0.309 0.000
M85.4 Solitary bone cyst
0.691 0.309 0.000
M85.3 Osteitis condensans
0.691 0.309 0.000
M85.1 Skeletal fluorosis
0.691 0.309 0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.690 0.310 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
T00-T07 Injuries involving multiple body regions
0.688 0.312 0.000
T59 Toxic effect of other gases, fumes and vapours
0.688 0.312 0.000
T90 Sequelae of injuries of head
0.688 0.312 0.000
T51.8 Other alcohols
0.684 0.316 0.000
T51.3 Fusel oil
0.684 0.316 0.000
T51.2 2-Propanol
0.684 0.316 0.000
T51.1 Methanol
0.684 0.316 0.000
Y64 Contaminated medical or biological substances
0.684 0.316 0.000
Y63 Failure in dosage during surgical and medical care
0.684 0.316 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.684 0.316 0.000
Y69 Unspecified misadventure during surgical and medical care
0.684 0.316 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.683 0.317 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.683 0.317 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.683 0.317 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.683 0.317 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
M46 Other inflammatory spondylopathies
0.681 0.319 0.000
M85.9 Disorder of bone density and structure, unspecified
0.680 0.319 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
S72.0 Fracture of neck of femur
0.680 0.320 0.000
T71 Asphyxiation
0.679 0.321 0.000
X84 Intentional self-harm by unspecified means
0.679 0.321 0.000
X83 Intentional self-harm by other specified means
0.679 0.321 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.679 0.321 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.679 0.321 0.000
X80 Intentional self-harm by jumping from a high place
0.679 0.321 0.000
X79 Intentional self-harm by blunt object
0.679 0.321 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.679 0.321 0.000
X76 Intentional self-harm by smoke, fire and flames
0.679 0.321 0.000
X75 Intentional self-harm by explosive material
0.679 0.321 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.679 0.321 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.679 0.321 0.000
X72 Intentional self-harm by handgun discharge
0.679 0.321 0.000
X71 Intentional self-harm by drowning and submersion
0.679 0.321 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.679 0.321 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.679 0.321 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.679 0.321 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
F43.2 Adjustment disorders
0.679 0.321 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.678 0.322 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.675 0.325 0.000
S58 Traumatic amputation of forearm
0.674 0.326 0.000
S57 Crushing injury of forearm
0.674 0.326 0.000
S55 Injury of blood vessels at forearm level
0.674 0.326 0.000
S81 Open wound of lower leg
0.674 0.326 0.000
V01 Pedestrian injured in collision with pedal cycle
0.672 0.328 0.000
M71 Other bursopathies
0.671 0.329 0.000
T56 Toxic effect of metals
0.670 0.330 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.666 0.334 0.000
S13.4 Sprain and strain of cervical spine
0.666 0.334 0.000
W87 Exposure to unspecified electric current
0.666 0.334 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.338 0.000
T78 Adverse effects, not elsewhere classified
0.662 0.338 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.660 0.339 0.000
T98 Sequelae of other and unspecified effects of external causes
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.660 0.340 0.000
E50-E64 Other nutritional deficiencies
0.660 0.340 0.000
M86.8 Other osteomyelitis
0.659 0.341 0.000
Q64 Other congenital malformations of urinary system
0.659 0.341 0.000
S72.20 Subtrochanteric fracture (closed)
0.659 0.341 0.000
M10.90 Gout, unspecified (Multiple sites)
0.659 0.341 0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.658 0.341 0.000
T50.7 Analeptics and opioid receptor antagonists
0.658 0.342 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.658 0.342 0.000
T50.5 Appetite depressants
0.658 0.342 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.658 0.342 0.000
T50.1 Loop [high-ceiling] diuretics
0.658 0.342 0.000
T50.0 Mineralocorticoids and their antagonists
0.658 0.342 0.000
F32.8 Other depressive episodes
0.657 0.343 0.000
M10.4 Other secondary gout
0.656 0.343 0.000
M10.3 Gout due to impairment of renal function
0.656 0.343 0.000
M10.2 Drug-induced gout
0.656 0.343 0.000
M10.1 Lead-induced gout
0.656 0.343 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.655 0.345 0.000
F22 Persistent delusional disorders
0.655 0.345 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.655 0.345 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.655 0.345 0.000
T50.8 Diagnostic agents
0.655 0.345 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.655 0.345 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.655 0.345 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.655 0.345 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.655 0.345 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.654 0.346 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.654 0.346 0.000
T19 Foreign body in genito-urinary tract
0.653 0.347 0.000
E20-E35 Disorders of other endocrine glands
0.653 0.347 0.000
S71 Open wound of hip and thigh
0.653 0.347 0.000
M07.3 Other psoriatic arthropathies
0.653 0.347 0.000
F31.8 Other bipolar affective disorders
0.652 0.347 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.652 0.348 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.348 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.651 0.349 0.000
M06.38 Rheumatoid nodule (Other)
0.651 0.349 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.651 0.349 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.651 0.349 0.000
M06.33 Rheumatoid nodule (Forearm)
0.651 0.349 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.651 0.349 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.651 0.349 0.000
W94 Exposure to high and low air pressure and changes in air pressure
0.649 0.351 0.000
Y61.0 During surgical operation
0.649 0.351 0.000
Q63 Other congenital malformations of kidney
0.649 0.351 0.000
T94.1 Sequelae of injuries, not specified by body region
0.649 0.351 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.649 0.351 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.649 0.351 0.000
S79 Other and unspecified injuries of hip and thigh
0.648 0.352 0.000
S56.7 Injury of multiple muscles and tendons at forearm level
0.647 0.353 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.647 0.353 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.647 0.353 0.000
X78.9 Unspecified place
0.646 0.354 0.000
X78.8 Other specified place
0.646 0.354 0.000
X78.7 Farm
0.646 0.354 0.000
X78.6 Industrial and construction area
0.646 0.354 0.000
X78.5 Trade and service area
0.646 0.354 0.000
X78.4 Street and highway
0.646 0.354 0.000
X78.3 Sports and athletics area
0.646 0.354 0.000
X78.2 School, other institution and public administrative area
0.646 0.354 0.000
X78.1 Residential institution
0.646 0.354 0.000
F30.0 Hypomania
0.646 0.354 0.000
M79.68 Pain in limb (Other)
0.645 0.355 0.000
F64 Gender identity disorders
0.645 0.355 0.000
T15 Foreign body on external eye
0.645 0.355 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.644 0.355 0.000
S31.8 Open wound of other and unspecified parts of abdomen
0.643 0.357 0.000
S10 Superficial injury of neck
0.643 0.357 0.000
F02.3 Dementia in Parkinson's disease
0.642 0.358 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.641 0.359 0.000
M81 Osteoporosis without pathological fracture
0.641 0.359 0.000
M86.6 Other chronic osteomyelitis
0.638 0.362 0.000
M79.9 Soft tissue disorder, unspecified
0.638 0.362 0.000
V78.1 Passenger injured in nontraffic accident
0.637 0.363 0.000
T63 Toxic effect of contact with venomous animals
0.637 0.363 0.000
T70 Effects of air pressure and water pressure
0.637 0.363 0.000
F23.8 Other acute and transient psychotic disorders
0.636 0.364 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.636 0.364 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.636 0.364 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.636 0.364 0.000
S32.40 Fracture of acetabulum (closed)
0.636 0.364 0.000
M77 Other enthesopathies
0.635 0.365 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.635 0.365 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.635 0.365 0.000
F68 Other disorders of adult personality and behaviour
0.635 0.365 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.635 0.365 0.000
F65 Disorders of sexual preference
0.635 0.365 0.000
F63 Habit and impulse disorders
0.635 0.365 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.635 0.365 0.000
F61 Mixed and other personality disorders
0.635 0.365 0.000
F40 Phobic anxiety disorders
0.634 0.366 0.000
S37 Injury of urinary and pelvic organs
0.633 0.366 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.632 0.368 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.632 0.368 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.632 0.368 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.632 0.368 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.632 0.368 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.632 0.368 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.632 0.368 0.000
M82.1 Osteoporosis in endocrine disorders
0.631 0.369 0.000
M11 Other crystal arthropathies
0.631 0.369 0.000
F43.1 Posttraumatic stress disorder
0.630 0.370 0.000
T95 Sequelae of burns, corrosions and frostbite
0.630 0.370 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.629 0.371 0.000
Q68 Other congenital musculoskeletal deformities
0.628 0.372 0.000
T14 Injury of unspecified body region
0.627 0.373 0.000
Y00.9 Unspecified place
0.626 0.374 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.625 0.375 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.624 0.376 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.624 0.376 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.624 0.376 0.000
M87.9 Osteonecrosis, unspecified
0.624 0.376 0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.624 0.376 0.000
X68.9 Unspecified place
0.623 0.377 0.000
Y60.9 During unspecified surgical and medical care
0.623 0.377 0.000
Y60.7 During administration of enema
0.623 0.377 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.623 0.377 0.000
Y60.5 During heart catheterisation
0.623 0.377 0.000
Y60.3 During injection or immunisation
0.623 0.377 0.000
Y60.2 During kidney dialysis or other perfusion
0.623 0.377 0.000
Y60.1 During infusion or transfusion
0.623 0.377 0.000
S11.9 Open wound of neck, part unspecified
0.623 0.377 0.000
S17 Crushing injury of neck
0.621 0.379 0.000
S15 Injury of blood vessels at neck level
0.621 0.379 0.000
S18 Traumatic amputation at neck level
0.621 0.379 0.000
S16 Injury of muscle and tendon at neck level
0.621 0.379 0.000
Y65.4 Failure to introduce or to remove other tube or instrument
0.620 0.380 0.000
E55 Vitamin D deficiency
0.620 0.380 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.619 0.381 0.000
X49.9 Unspecified place
0.619 0.381 0.000
F25.8 Other schizoaffective disorders
0.618 0.382 0.000
F25.2 Schizoaffective disorder, mixed type
0.618 0.382 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.618 0.382 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.618 0.382 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.618 0.382 0.000
S86 Injury of muscle and tendon at lower leg level
0.618 0.382 0.000
V80-V89 Other land transport accidents
0.615 0.385 0.000
T43.6 Psychostimulants with abuse potential
0.615 0.385 0.000
T45.0 Antiallergic and antiemetic drugs
0.614 0.386 0.000
T51.9 Alcohol, unspecified
0.613 0.387 0.000
S54.1 Injury of median nerve at forearm level
0.612 0.388 0.000
S36.8 Injury of other intra-abdominal organs
0.611 0.389 0.000
S72.00 Fracture of neck of femur (closed)
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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