TreeWAS – Variant ID: rs139806220

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	0.000	0.047	0.953
I51 Complications and ill-defined descriptions of heart disease	0.000	0.056	0.944
I50 Heart failure	0.000	0.080	0.920
I51.8 Other ill-defined heart diseases	0.000	0.095	0.905
I47 Paroxysmal tachycardia	0.000	0.096	0.904
I51.7 Cardiomegaly	0.000	0.096	0.904
I42 Cardiomyopathy	0.000	0.112	0.888
I34 Nonrheumatic mitral valve disorders	0.000	0.117	0.883
I44 Atrioventricular and left bundle-branch block	0.000	0.119	0.881
I50.1 Left ventricular failure	0.000	0.127	0.873
I34.0 Mitral (valve) insufficiency	0.000	0.146	0.854
I44.7 Left bundle-branch block, unspecified	0.000	0.183	0.817
I31 Other diseases of pericardium	0.000	0.183	0.817
I47.1 Supraventricular tachycardia	0.000	0.197	0.803
I47.2 Ventricular tachycardia	0.000	0.203	0.797
I42.0 Dilated cardiomyopathy	0.000	0.226	0.774
I50.0 Congestive heart failure	0.000	0.233	0.767
I44.0 Atrioventricular block, first degree	0.000	0.236	0.764
I33 Acute and subacute endocarditis	0.000	0.243	0.757
I31.9 Disease of pericardium, unspecified	0.000	0.243	0.757
I35 Nonrheumatic aortic valve disorders	0.000	0.258	0.742
I42.2 Other hypertrophic cardiomyopathy	0.000	0.264	0.736
I45 Other conduction disorders	0.000	0.271	0.729
I51.9 Heart disease, unspecified	0.000	0.274	0.726
I50.9 Heart failure, unspecified	0.000	0.298	0.702
I30 Acute pericarditis	0.000	0.302	0.698
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.309	0.691
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.316	0.684
I52 Other heart disorders in diseases classified elsewhere	0.000	0.317	0.683
I48 Atrial fibrillation and flutter	0.000	0.317	0.683
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.317	0.683
I41 Myocarditis in diseases classified elsewhere	0.000	0.317	0.683
I40 Acute myocarditis	0.000	0.317	0.683
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.317	0.683
I37 Pulmonary valve disorders	0.000	0.317	0.683
I36 Nonrheumatic tricuspid valve disorders	0.000	0.317	0.683
I32 Pericarditis in diseases classified elsewhere	0.000	0.317	0.683
I42.9 Cardiomyopathy, unspecified	0.000	0.318	0.682
I51.6 Cardiovascular disease, unspecified	0.000	0.323	0.677
I51.5 Myocardial degeneration	0.000	0.323	0.677
I51.4 Myocarditis, unspecified	0.000	0.323	0.677
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.323	0.677
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.323	0.677
I51.0 Cardiac septal defect, acquired	0.000	0.323	0.677
I46 Cardiac arrest	0.000	0.335	0.665
I47.0 Reentry ventricular arrhythmia	0.000	0.352	0.648
I45.1 Other and unspecified right bundle-branch block	0.000	0.358	0.642
I42.8 Other cardiomyopathies	0.000	0.363	0.637
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.363	0.637
I42.6 Alcoholic cardiomyopathy	0.000	0.363	0.637
I42.5 Other restrictive cardiomyopathy	0.000	0.363	0.637
I42.4 Endocardial fibroelastosis	0.000	0.363	0.637
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.363	0.637
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.367	0.633
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.367	0.633
I44.5 Left posterior fascicular block	0.000	0.368	0.632
I44.4 Left anterior fascicular block	0.000	0.368	0.632
I44.3 Other and unspecified atrioventricular block	0.000	0.368	0.632
I33.0 Acute and subacute infective endocarditis	0.000	0.383	0.617
I44.1 Atrioventricular block, second degree	0.000	0.383	0.617
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.388	0.611
I44.6 Other and unspecified fascicular block	0.000	0.397	0.603
I34.1 Mitral (valve) prolapse	0.000	0.400	0.600
I31.8 Other specified diseases of pericardium	0.000	0.414	0.586
I31.2 Haemopericardium, not elsewhere classified	0.000	0.414	0.586
I31.1 Chronic constrictive pericarditis	0.000	0.414	0.586
I31.0 Chronic adhesive pericarditis	0.000	0.414	0.586
I35.9 Aortic valve disorder, unspecified	0.000	0.414	0.586
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.415	0.585
I30.9 Acute pericarditis, unspecified	0.000	0.450	0.550
I33.9 Acute endocarditis, unspecified	0.000	0.457	0.543
I35.8 Other aortic valve disorders	0.000	0.460	0.540
I49 Other cardiac arrhythmias	0.000	0.464	0.536
I35.1 Aortic (valve) insufficiency	0.000	0.466	0.534
I45.8 Other specified conduction disorders	0.000	0.477	0.523
I45.4 Nonspecific intraventricular block	0.000	0.477	0.523
I45.3 Trifascicular block	0.000	0.477	0.523
I45.0 Right fascicular block	0.000	0.477	0.523
I46.0 Cardiac arrest with successful resuscitation	0.000	0.479	0.521
I44.2 Atrioventricular block, complete	0.000	0.483	0.517
I45.9 Conduction disorder, unspecified	0.000	0.494	0.506
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.496	0.503
I30.8 Other forms of acute pericarditis	0.000	0.499	0.500
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.499	0.500
I45.2 Bifascicular block	0.000	0.501	0.499
I45.5 Other specified heart block	0.000	0.501	0.499
I38 Endocarditis, valve unspecified	0.000	0.510	0.490
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.510	0.490
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.510	0.490
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.510	0.490
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.510	0.490
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.510	0.490
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.510	0.490
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.510	0.490
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.510	0.490
I37.9 Pulmonary valve disorder, unspecified	0.000	0.510	0.490
I37.8 Other pulmonary valve disorders	0.000	0.510	0.490
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.510	0.490
I37.1 Pulmonary valve insufficiency	0.000	0.510	0.490
I37.0 Pulmonary valve stenosis	0.000	0.510	0.490
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.510	0.490
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.510	0.490
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.510	0.490
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.510	0.490
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.510	0.490
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.510	0.490
I40.9 Acute myocarditis, unspecified	0.000	0.510	0.490
I40.8 Other acute myocarditis	0.000	0.510	0.490
I40.1 Isolated myocarditis	0.000	0.510	0.490
I40.0 Infective myocarditis	0.000	0.510	0.490
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.510	0.490
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.510	0.490
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.510	0.490
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.510	0.490
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.510	0.490
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.510	0.490
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.510	0.490
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.510	0.490
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.510	0.490
I48.4 Atypical atrial flutter	0.000	0.510	0.490
I48.3 Typical atrial flutter	0.000	0.510	0.490
I48.2 Chronic atrial fibrillation	0.000	0.510	0.490
I48.1 Persistent atrial fibrillation	0.000	0.510	0.490
I48.0 Paroxysmal atrial fibrillation	0.000	0.510	0.490
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.510	0.490
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.510	0.490
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.510	0.490
I46.1 Sudden cardiac death, so described	0.000	0.523	0.477
I35.0 Aortic (valve) stenosis	0.000	0.542	0.458
I49.5 Sick sinus syndrome	0.000	0.543	0.457
I30.1 Infective pericarditis	0.000	0.545	0.455
I31.3 Pericardial effusion (noninflammatory)	0.000	0.555	0.445
I45.6 Preexcitation syndrome	0.000	0.556	0.444
I49.4 Other and unspecified premature depolarisation	0.000	0.577	0.423
I46.9 Cardiac arrest, unspecified	0.000	0.605	0.395
I49.2 Junctional premature depolarisation	0.000	0.615	0.384
I49.1 Atrial premature depolarisation	0.000	0.632	0.368
I49.0 Ventricular fibrillation and flutter	0.000	0.641	0.358
I49.3 Ventricular premature depolarisation	0.000	0.650	0.350
I49.8 Other specified cardiac arrhythmias	0.000	0.725	0.274
I49.9 Cardiac arrhythmia, unspecified	0.000	0.742	0.258
K59.0 Constipation	0.000	0.929	0.071
I60-I69 Cerebrovascular diseases	0.000	0.959	0.041
Chapter IX Diseases of the circulatory system	0.000	0.959	0.041
I67 Other cerebrovascular diseases	0.000	0.960	0.040
I67.8 Other specified cerebrovascular diseases	0.000	0.961	0.039
I67.2 Cerebral atherosclerosis	0.000	0.966	0.034
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.966	0.034
I69 Sequelae of cerebrovascular disease	0.000	0.966	0.034
I67.9 Cerebrovascular disease, unspecified	0.000	0.967	0.033
I62 Other nontraumatic intracranial haemorrhage	0.000	0.967	0.033
I60 Subarachnoid haemorrhage	0.000	0.967	0.033
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.967	0.033
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.970	0.030
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.970	0.030
I00-I02 Acute rheumatic fever	0.000	0.971	0.029
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.971	0.029
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.971	0.029
I67.5 Moyamoya disease	0.000	0.971	0.029
I67.4 Hypertensive encephalopathy	0.000	0.971	0.029
I67.3 Progressive vascular leukoencephalopathy	0.000	0.971	0.029
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.971	0.029
I65.2 Occlusion and stenosis of carotid artery	0.000	0.971	0.029
I69.3 Sequelae of cerebral infarction	0.000	0.971	0.029
I61 Intracerebral haemorrhage	0.000	0.971	0.029
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.971	0.028
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.972	0.028
I05-I09 Chronic rheumatic heart diseases	0.000	0.974	0.026
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.974	0.026
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.975	0.025
K59 Other functional intestinal disorders	0.000	0.975	0.025
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.975	0.024
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.975	0.024
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.975	0.024
I65.1 Occlusion and stenosis of basilar artery	0.000	0.975	0.024
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.975	0.024
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.975	0.024
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.975	0.024
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.975	0.024
I62.1 Nontraumatic extradural haemorrhage	0.000	0.976	0.024
I60.8 Other subarachnoid haemorrhage	0.000	0.976	0.024
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.976	0.024
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.976	0.024
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.976	0.024
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.976	0.024
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.976	0.024
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.976	0.024
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.976	0.023
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.977	0.023
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.977	0.022
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.978	0.022
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.978	0.021
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.978	0.021
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.978	0.021
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.978	0.021
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.978	0.021
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.978	0.021
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.978	0.021
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.978	0.021
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.978	0.021
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.978	0.021
I68.0 Cerebral amyloid angiopathy	0.000	0.978	0.021
I67.1 Cerebral aneurysm, nonruptured	0.000	0.978	0.021
I08 Multiple valve diseases	0.000	0.978	0.021
Chapter XV Pregnancy, childbirth and the puerperium	0.022	0.978	0.000
I02 Rheumatic chorea	0.000	0.979	0.021
I01 Rheumatic fever with heart involvement	0.000	0.979	0.021
I00 Rheumatic fever without mention of heart involvement	0.000	0.979	0.021
O63.1 Prolonged second stage (of labour)	0.021	0.979	0.000
O60-O75 Complications of labour and delivery	0.021	0.979	0.000
O63 Long labour	0.021	0.979	0.000
O72 Postpartum haemorrhage	0.021	0.979	0.000
O72.1 Other immediate postpartum haemorrhage	0.021	0.979	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.979	0.021
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.979	0.021
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.979	0.021
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.979	0.021
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.979	0.021
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.979	0.021
O94-O99 Other obstetric conditions, not elsewhere classified	0.021	0.979	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.980	0.020
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.020	0.980	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.980	0.020
K59.8 Other specified functional intestinal disorders	0.000	0.981	0.019
O20-O29 Other maternal disorders predominantly related to pregnancy	0.019	0.981	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.019	0.981	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.981	0.019
I06 Rheumatic aortic valve diseases	0.000	0.981	0.019
I10-I15 Hypertensive diseases	0.000	0.981	0.019
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.982	0.018
O85-O92 Complications predominantly related to the puerperium	0.018	0.982	0.000
O72.0 Third-stage haemorrhage	0.018	0.982	0.000
K59.4 Anal spasm	0.000	0.982	0.018
K59.2 Neurogenic bowel, not elsewhere classified	0.000	0.982	0.018
O26.9 Pregnancy-related condition, unspecified	0.018	0.982	0.000
O62 Abnormalities of forces of labour	0.018	0.982	0.000
I05 Rheumatic mitral valve diseases	0.000	0.982	0.018
K59.1 Functional diarrhoea	0.000	0.982	0.018
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.982	0.018
O71 Other obstetric trauma	0.018	0.982	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.018	0.982	0.000
I27 Other pulmonary heart diseases	0.000	0.983	0.017
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.017	0.983	0.000
K59.9 Functional intestinal disorder, unspecified	0.000	0.983	0.017
I28 Other diseases of pulmonary vessels	0.000	0.983	0.017
O63.9 Long labour, unspecified	0.017	0.983	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.017	0.983	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.983	0.017
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.017	0.983	0.000
I09 Other rheumatic heart diseases	0.000	0.983	0.016
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.016	0.983	0.000
O66 Other obstructed labour	0.016	0.984	0.000
O86 Other puerperal infections	0.016	0.984	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.016	0.984	0.000
O00-O08 Pregnancy with abortive outcome	0.016	0.984	0.000
O61 Failed induction of labour	0.016	0.984	0.000
O24 Diabetes mellitus in pregnancy	0.016	0.984	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.984	0.016
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.984	0.015
I01.8 Other acute rheumatic heart disease	0.000	0.984	0.015
I01.2 Acute rheumatic myocarditis	0.000	0.984	0.015
I01.1 Acute rheumatic endocarditis	0.000	0.984	0.015
I01.0 Acute rheumatic pericarditis	0.000	0.984	0.015
I02.9 Rheumatic chorea without heart involvement	0.000	0.984	0.015
I02.0 Rheumatic chorea with heart involvement	0.000	0.984	0.015
O74 Complications of anaesthesia during labour and delivery	0.015	0.984	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.015	0.984	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.015	0.984	0.000
O60 Preterm delivery	0.015	0.984	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.015	0.984	0.000
O16 Unspecified maternal hypertension	0.015	0.985	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.015	0.985	0.000
I20-I25 Ischaemic heart diseases	0.000	0.985	0.015
I08.8 Other multiple valve diseases	0.000	0.985	0.015
O72.3 Postpartum coagulation defects	0.015	0.985	0.000
I11 Hypertensive heart disease	0.000	0.985	0.015
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.015	0.985	0.000
K59.3 Megacolon, not elsewhere classified	0.000	0.985	0.015
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.000	0.985	0.015
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O97 Death from sequelae of direct obstetric causes	0.015	0.985	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.015	0.985	0.000
O95 Obstetric death of unspecified cause	0.015	0.985	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O71.4 Obstetric high vaginal laceration alone	0.015	0.985	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O14.9 Preeclampsia, unspecified	0.015	0.985	0.000
O63.0 Prolonged first stage (of labour)	0.015	0.985	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
O73 Retained placenta and membranes, without haemorrhage	0.015	0.985	0.000
O23 Infections of genito-urinary tract in pregnancy	0.014	0.985	0.000
O62.0 Primary inadequate contractions	0.014	0.986	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.014	0.986	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.986	0.014
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.986	0.014
O29 Complications of anaesthesia during pregnancy	0.014	0.986	0.000
O28 Abnormal findings on antenatal screening of mother	0.014	0.986	0.000
O22 Venous complications in pregnancy	0.014	0.986	0.000
O25 Malnutrition in pregnancy	0.014	0.986	0.000
O15 Eclampsia	0.014	0.986	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.014	0.986	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.014	0.986	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.986	0.014
I06.8 Other rheumatic aortic valve diseases	0.000	0.986	0.014
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.986	0.014
I06.1 Rheumatic aortic insufficiency	0.000	0.986	0.014
I06.0 Rheumatic aortic stenosis	0.000	0.986	0.014
I13 Hypertensive heart and renal disease	0.000	0.986	0.014
O48 Prolonged pregnancy	0.014	0.986	0.000
O86.2 Urinary tract infection following delivery	0.014	0.986	0.000
I15 Secondary hypertension	0.000	0.986	0.014
I21 Acute myocardial infarction	0.000	0.986	0.014
O80-O84 Delivery	0.014	0.986	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.986	0.013
O20 Haemorrhage in early pregnancy	0.013	0.987	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.013	0.987	0.000
O91 Infections of breast associated with childbirth	0.013	0.987	0.000
O89 Complications of anaesthesia during the puerperium	0.013	0.987	0.000
O88 Obstetric embolism	0.013	0.987	0.000
O87 Venous complications in the puerperium	0.013	0.987	0.000
O85 Puerperal sepsis	0.013	0.987	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.013	0.987	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.987	0.013
O43 Placental disorders	0.013	0.987	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.013	0.987	0.000
O86.0 Infection of obstetric surgical wound	0.013	0.987	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.987	0.013
O03 Spontaneous abortion	0.013	0.987	0.000
O42 Premature rupture of membranes	0.013	0.987	0.000
O62.9 Abnormality of forces of labour, unspecified	0.013	0.987	0.000
O62.8 Other abnormalities of forces of labour	0.013	0.987	0.000
O62.1 Secondary uterine inertia	0.013	0.987	0.000
O90 Complications of the puerperium, not elsewhere classified	0.013	0.987	0.000
I12 Hypertensive renal disease	0.000	0.987	0.013
I05.8 Other mitral valve diseases	0.000	0.987	0.013
I05.1 Rheumatic mitral insufficiency	0.000	0.987	0.013
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.987	0.013
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.013	0.987	0.000
O71.9 Obstetric trauma, unspecified	0.013	0.987	0.000
O71.8 Other specified obstetric trauma	0.013	0.987	0.000
O71.7 Obstetric haematoma of pelvis	0.013	0.987	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.013	0.987	0.000
O71.5 Other obstetric injury to pelvic organs	0.013	0.987	0.000
O71.3 Obstetric laceration of cervix	0.013	0.987	0.000
O71.2 Postpartum inversion of uterus	0.013	0.987	0.000
O71.1 Rupture of uterus during labour	0.013	0.987	0.000
O71.0 Rupture of uterus before onset of labour	0.013	0.987	0.000
O14.1 Severe preeclampsia	0.013	0.987	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O26.5 Maternal hypotension syndrome	0.013	0.987	0.000
O26.4 Herpes gestationis	0.013	0.987	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.013	0.987	0.000
O26.2 Pregnancy care of habitual aborter	0.013	0.987	0.000
O26.1 Low weight gain in pregnancy	0.013	0.987	0.000
O26.0 Excessive weight gain in pregnancy	0.013	0.987	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.013	0.987	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.013	0.987	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.013	0.987	0.000
O21 Excessive vomiting in pregnancy	0.013	0.987	0.000
O45 Premature separation of placenta [abruptio placentae]	0.013	0.987	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.987	0.012
I27.1 Kyphoscoliotic heart disease	0.000	0.987	0.012
O62.3 Precipitate labour	0.012	0.987	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.987	0.012
I28.8 Other specified diseases of pulmonary vessels	0.000	0.987	0.012
I28.1 Aneurysm of pulmonary artery	0.000	0.987	0.012
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.987	0.012
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.987	0.013
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.987	0.012
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.988	0.012
O12.0 Gestational oedema	0.012	0.988	0.000
O40 Polyhydramnios	0.012	0.988	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.988	0.012
O62.2 Other uterine inertia	0.012	0.988	0.000
O14.2 HELLP syndrome	0.012	0.988	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.012	0.988	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.988	0.012
I07.8 Other tricuspid valve diseases	0.000	0.988	0.012
I07.2 Tricuspid stenosis with insufficiency	0.000	0.988	0.012
I07.0 Tricuspid stenosis	0.000	0.988	0.012
I22 Subsequent myocardial infarction	0.000	0.988	0.012
I05.2 Mitral stenosis with insufficiency	0.000	0.988	0.012
I09.8 Other specified rheumatic heart diseases	0.000	0.988	0.012
I09.2 Chronic rheumatic pericarditis	0.000	0.988	0.012
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.988	0.012
I09.0 Rheumatic myocarditis	0.000	0.988	0.012
O61.0 Failed medical induction of labour	0.012	0.988	0.000
O14.0 Moderate preeclampsia	0.012	0.988	0.000
I05.0 Mitral stenosis	0.000	0.988	0.012
O02 Other abnormal products of conception	0.012	0.988	0.000
I27.0 Primary pulmonary hypertension	0.000	0.988	0.012
O86.4 Pyrexia of unknown origin following delivery	0.012	0.988	0.000
O66.9 Obstructed labour, unspecified	0.012	0.988	0.000
O66.8 Other specified obstructed labour	0.012	0.988	0.000
O66.4 Failed trial of labour, unspecified	0.012	0.988	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.012	0.988	0.000
O66.2 Obstructed labour due to unusually large foetus	0.012	0.988	0.000
O66.1 Obstructed labour due to locked twins	0.012	0.988	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.988	0.012
O86.8 Other specified puerperal infections	0.012	0.988	0.000
O86.3 Other genito-urinary tract infections following delivery	0.012	0.988	0.000
O86.1 Other infection of genital tract following delivery	0.012	0.988	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.012	0.988	0.000
O36 Maternal care for other known or suspected foetal problems	0.012	0.988	0.000
O33 Maternal care for known or suspected disproportion	0.012	0.988	0.000
O31 Complications specific to multiple gestation	0.012	0.988	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O07 Failed attempted abortion	0.012	0.988	0.000
O06 Unspecified abortion	0.012	0.988	0.000
O05 Other abortion	0.012	0.988	0.000
O01 Hydatidiform mole	0.012	0.988	0.000
O43.8 Other placental disorders	0.012	0.988	0.000
O61.9 Failed induction of labour, unspecified	0.012	0.988	0.000
O61.8 Other failed induction of labour	0.012	0.988	0.000
O61.1 Failed instrumental induction of labour	0.012	0.988	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.012	0.988	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.011	0.988	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.011	0.988	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.011	0.988	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.011	0.988	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.011	0.988	0.000
O04 Medical abortion	0.012	0.988	0.000
O44 Placenta praevia	0.011	0.988	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.011	0.988	0.000
O60.3 Preterm delivery without spontaneous labour	0.011	0.989	0.000
O60.2 Preterm spontaneous labour with term delivery	0.011	0.989	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.011	0.989	0.000
O60.0 Preterm labour without delivery	0.011	0.989	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.011	0.989	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.011	0.989	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.011	0.989	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.011	0.989	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.011	0.989	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.011	0.989	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.011	0.989	0.000
O65.0 Obstructed labour due to deformed pelvis	0.011	0.989	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.011	0.989	0.000
O67.8 Other intrapartum haemorrhage	0.011	0.989	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.011	0.989	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.011	0.989	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.011	0.989	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.011	0.989	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.011	0.989	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.011	0.989	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.011	0.989	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.011	0.989	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.011	0.989	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.011	0.989	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.011	0.989	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.011	0.989	0.000
O75.8 Other specified complications of labour and delivery	0.011	0.989	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.989	0.011
O23.4 Unspecified infection of urinary tract in pregnancy	0.011	0.989	0.000
O41 Other disorders of amniotic fluid and membranes	0.011	0.989	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.989	0.011
O12.2 Gestational oedema with proteinuria	0.011	0.989	0.000
O12.1 Gestational proteinuria	0.011	0.989	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.989	0.011
I12.9 Hypertensive renal disease without renal failure	0.000	0.989	0.011
O03.4 Incomplete, without complication	0.011	0.989	0.000
O96.9 Death from unspecified obstetric cause	0.011	0.989	0.000
O96.1 Death from indirect obstetric cause	0.011	0.989	0.000
O96.0 Death from direct obstetric cause	0.011	0.989	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.011	0.989	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.011	0.989	0.000
O97.0 Death from sequelae of direct obstetric cause	0.011	0.989	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O30 Multiple gestation	0.011	0.989	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.989	0.011
O20.0 Threatened abortion	0.011	0.989	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.011	0.989	0.000
I26 Pulmonary embolism	0.000	0.989	0.011
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.010	0.989	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.010	0.989	0.000
O23.2 Infections of urethra in pregnancy	0.010	0.989	0.000
O23.1 Infections of bladder in pregnancy	0.010	0.989	0.000
O23.0 Infections of kidney in pregnancy	0.010	0.989	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.011	0.989	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.989	0.011
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.989	0.010
I63 Cerebral infarction	0.000	0.989	0.010
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.010	0.989	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.010	0.989	0.000
O64.5 Obstructed labour due to compound presentation	0.010	0.989	0.000
O64.4 Obstructed labour due to shoulder presentation	0.010	0.989	0.000
O64.3 Obstructed labour due to brow presentation	0.010	0.989	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations