TreeWAS – Variant ID: rs1406503

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I84.2 Internal haemorrhoids without complication	0.617	0.383	0.000
I84 Haemorrhoids	0.594	0.406	0.000
I84.6 Residual haemorrhoidal skin tags	0.584	0.416	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.488	0.512	0.000
I84.5 External haemorrhoids without complication	0.483	0.517	0.000
I84.3 External thrombosed haemorrhoids	0.481	0.519	0.000
I86 Varicose veins of other sites	0.447	0.552	0.000
I82 Other venous embolism and thrombosis	0.446	0.554	0.000
I84.8 Unspecified haemorrhoids with other complications	0.439	0.561	0.000
I84.9 Unspecified haemorrhoids without complication	0.431	0.569	0.000
I84.0 Internal thrombosed haemorrhoids	0.428	0.572	0.000
I82.8 Embolism and thrombosis of other specified veins	0.421	0.579	0.000
I87 Other disorders of veins	0.411	0.589	0.000
I86.1 Scrotal varices	0.411	0.589	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.397	0.603	0.000
I83 Varicose veins of lower extremities	0.364	0.636	0.000
I81 Portal vein thrombosis	0.354	0.646	0.000
I88 Nonspecific lymphadenitis	0.350	0.650	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.347	0.653	0.000
I86.4 Gastric varices	0.346	0.653	0.000
I87.8 Other specified disorders of veins	0.338	0.662	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.336	0.664	0.000
I87.1 Compression of vein	0.326	0.674	0.000
I82.2 Embolism and thrombosis of vena cava	0.325	0.675	0.000
I86.8 Varicose veins of other specified sites	0.321	0.679	0.000
I86.3 Vulval varices	0.321	0.679	0.000
I86.2 Pelvic varices	0.321	0.679	0.000
I86.0 Sublingual varices	0.321	0.679	0.000
I82.3 Embolism and thrombosis of renal vein	0.320	0.680	0.000
I82.1 Thrombophlebitis migrans	0.320	0.680	0.000
I82.0 Budd-Chiari syndrome	0.320	0.680	0.000
I84.4 External haemorrhoids with other complications	0.304	0.695	0.000
I87.9 Disorder of vein, unspecified	0.295	0.705	0.000
I87.0 Postphlebitic syndrome	0.295	0.705	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.292	0.708	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.290	0.709	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.278	0.722	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.266	0.734	0.000
I85 Oesophageal varices	0.261	0.739	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.261	0.739	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.257	0.743	0.000
I89.1 Lymphangitis	0.256	0.744	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.251	0.749	0.000
I88.8 Other nonspecific lymphadenitis	0.251	0.749	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.251	0.749	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.251	0.749	0.000
I80 Phlebitis and thrombophlebitis	0.205	0.795	0.000
I85.0 Oesophageal varices with bleeding	0.187	0.812	0.000
I89.0 Lymphoedema, not elsewhere classified	0.174	0.825	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.167	0.833	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.146	0.853	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.141	0.859	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.137	0.863	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.104	0.896	0.000
I85.9 Oesophageal varices without bleeding	0.098	0.901	0.001
I84.1 Internal haemorrhoids with other complications	0.097	0.902	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.071	0.929	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.030	0.970	0.000
G56.2 Lesion of ulnar nerve	0.026	0.974	0.000
Z80 Family history of malignant neoplasm	0.018	0.982	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.018	0.982	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.017	0.983	0.000
G56 Mononeuropathies of upper limb	0.017	0.983	0.000
Z80.3 Family history of malignant neoplasm of breast	0.017	0.983	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.016	0.984	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.016	0.984	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.015	0.985	0.000
G56.8 Other mononeuropathies of upper limb	0.014	0.986	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.014	0.986	0.000
Z80.6 Family history of leukaemia	0.014	0.986	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.013	0.986	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.012	0.988	0.000
G56.4 Causalgia	0.012	0.988	0.000
G56.3 Lesion of radial nerve	0.012	0.988	0.000
G56.1 Other lesions of median nerve	0.012	0.988	0.000
G56.0 Carpal tunnel syndrome	0.011	0.989	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.009	0.991	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.007	0.993	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.007	0.993	0.000
T43.2 Other and unspecified antidepressants	0.000	0.993	0.007
G70.0 Myasthenia gravis	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.994	0.006
G70 Myasthenia gravis and other myoneural disorders	0.006	0.994	0.000
Chapter VI Diseases of the nervous system	0.006	0.994	0.000
I77.1 Stricture of artery	0.000	0.994	0.006
G70-G73 Diseases of myoneural junction and muscle	0.006	0.994	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.006	0.994	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.994	0.006
G20-G26 Extrapyramidal and movement disorders	0.006	0.994	0.000
G24 Dystonia	0.006	0.994	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.005	0.994	0.000
G52 Disorders of other cranial nerves	0.005	0.995	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.005
G04 Encephalitis, myelitis and encephalomyelitis	0.005	0.995	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.005	0.995	0.000
G24.9 Dystonia, unspecified	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
G54 Nerve root and plexus disorders	0.005	0.995	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.995	0.005
G55.3 Nerve root and plexus compressions in other dorsopathies	0.005	0.995	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.005	0.995	0.000
G90-G99 Other disorders of the nervous system	0.005	0.995	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.005	0.995	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.005	0.995	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.005	0.995	0.000
G58 Other mononeuropathies	0.005	0.995	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.005	0.995	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.005	0.995	0.000
G25 Other extrapyramidal and movement disorders	0.005	0.995	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.995	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T43.6 Psychostimulants with abuse potential	0.000	0.995	0.005
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.995	0.005
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
G71 Primary disorders of muscles	0.005	0.995	0.000
G70.9 Myoneural disorder, unspecified	0.005	0.995	0.000
G70.8 Other specified myoneural disorders	0.005	0.995	0.000
G70.2 Congenital and developmental myasthenia	0.005	0.995	0.000
G70.1 Toxic myoneural disorders	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.005	0.995	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.005	0.995	0.000
G72 Other myopathies	0.005	0.995	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.005	0.995	0.000
G63.2 Diabetic polyneuropathy	0.005	0.995	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.005	0.995	0.000
G03 Meningitis due to other and unspecified causes	0.005	0.995	0.000
G00 Bacterial meningitis, not elsewhere classified	0.005	0.995	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.005	0.995	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.005	0.995	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.005	0.995	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.005	0.995	0.000
G50 Disorders of trigeminal nerve	0.005	0.995	0.000
G95 Other diseases of spinal cord	0.005	0.995	0.000
G23 Other degenerative diseases of basal ganglia	0.004	0.995	0.000
G21 Secondary Parkinsonism	0.004	0.995	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.004	0.995	0.000
G22 Parkinsonism in diseases classified elsewhere	0.004	0.995	0.000
G24.5 Blepharospasm	0.004	0.995	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.000	0.995	0.005
G57 Mononeuropathies of lower limb	0.004	0.995	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.004	0.996	0.000
G60 Hereditary and idiopathic neuropathy	0.004	0.996	0.000
G25.0 Essential tremor	0.004	0.996	0.000
G24.8 Other dystonia	0.004	0.996	0.000
G24.4 Idiopathic orofacial dystonia	0.004	0.996	0.000
G24.3 Spasmodic torticollis	0.004	0.996	0.000
G24.2 Idiopathic nonfamilial dystonia	0.004	0.996	0.000
G24.1 Idiopathic familial dystonia	0.004	0.996	0.000
G24.0 Drug-induced dystonia	0.004	0.996	0.000
G95.2 Cord compression, unspecified	0.004	0.996	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
G02.1 Meningitis in mycoses	0.004	0.996	0.000
G06.1 Intraspinal abscess and granuloma	0.004	0.996	0.000
G52.9 Cranial nerve disorder, unspecified	0.004	0.996	0.000
G52.8 Disorders of other specified cranial nerves	0.004	0.996	0.000
G52.7 Disorders of multiple cranial nerves	0.004	0.996	0.000
G52.3 Disorders of hypoglossal nerve	0.004	0.996	0.000
G52.2 Disorders of vagus nerve	0.004	0.996	0.000
G52.1 Disorders of glossopharyngeal nerve	0.004	0.996	0.000
G52.0 Disorders of olfactory nerve	0.004	0.996	0.000
G20 Parkinson's disease	0.004	0.996	0.000
G51 Facial nerve disorders	0.004	0.996	0.000
G64 Other disorders of peripheral nervous system	0.004	0.996	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.004	0.996	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.004	0.996	0.000
G04.1 Tropical spastic paraplegia	0.004	0.996	0.000
G04.0 Acute disseminated encephalitis	0.004	0.996	0.000
G96 Other disorders of central nervous system	0.004	0.996	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.004	0.996	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.004	0.996	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.004	0.996	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.004	0.996	0.000
G61 Inflammatory polyneuropathy	0.004	0.996	0.000
G90 Disorders of autonomic nervous system	0.004	0.996	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.004	0.996	0.000
G54.8 Other nerve root and plexus disorders	0.004	0.996	0.000
G54.7 Phantom limb syndrome without pain	0.004	0.996	0.000
G54.6 Phantom limb syndrome with pain	0.004	0.996	0.000
G54.5 Neuralgic amyotrophy	0.004	0.996	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.004	0.996	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.004	0.996	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.004	0.996	0.000
G54.1 Lumbosacral plexus disorders	0.004	0.996	0.000
G25.3 Myoclonus	0.004	0.996	0.000
G12 Spinal muscular atrophy and related syndromes	0.004	0.996	0.000
G53.0 Postzoster neuralgia	0.004	0.996	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.004	0.996	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.004	0.996	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.004	0.996	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.004	0.996	0.000
G92 Toxic encephalopathy	0.004	0.996	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.004	0.996	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.004	0.996	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.004	0.996	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.004	0.996	0.000
G62 Other polyneuropathies	0.004	0.996	0.000
G83 Other paralytic syndromes	0.004	0.996	0.000
G06.2 Extradural and subdural abscess, unspecified	0.004	0.996	0.000
G06.0 Intracranial abscess and granuloma	0.004	0.996	0.000
G54.0 Brachial plexus disorders	0.004	0.996	0.000
G58.7 Mononeuritis multiplex	0.004	0.996	0.000
G58.0 Intercostal neuropathy	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.004	0.996	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.004	0.996	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.004	0.996	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.004	0.996	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.004	0.996	0.000
G63.1 Polyneuropathy in neoplastic disease	0.004	0.996	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
M81.9 Osteoporosis, unspecified	0.004	0.996	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.004	0.996	0.000
G11 Hereditary ataxia	0.004	0.996	0.000
G14 Postpolio syndrome	0.004	0.996	0.000
G10 Huntington's disease	0.004	0.996	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.004	0.996	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.004	0.996	0.000
G25.5 Other chorea	0.004	0.996	0.000
G25.4 Drug-induced chorea	0.004	0.996	0.000
G25.2 Other specified forms of tremor	0.004	0.996	0.000
G25.1 Drug-induced tremor	0.004	0.996	0.000
G71.0 Muscular dystrophy	0.004	0.996	0.000
G91 Hydrocephalus	0.004	0.996	0.000
G71.9 Primary disorder of muscle, unspecified	0.003	0.996	0.000
G71.8 Other primary disorders of muscles	0.003	0.996	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.003	0.996	0.000
G71.2 Congenital myopathies	0.003	0.996	0.000
G71.1 Myotonic disorders	0.003	0.996	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
G72.9 Myopathy, unspecified	0.003	0.996	0.000
G72.8 Other specified myopathies	0.003	0.996	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.003	0.996	0.000
G72.3 Periodic paralysis	0.003	0.996	0.000
G72.2 Myopathy due to other toxic agents	0.003	0.996	0.000
G72.1 Alcoholic myopathy	0.003	0.996	0.000
G72.0 Drug-induced myopathy	0.003	0.996	0.000
G73.7 Myopathy other diseases classified elsewhere	0.003	0.996	0.000
G73.6 Myopathy in metabolic diseases	0.003	0.996	0.000
G73.5 Myopathy in endocrine diseases	0.003	0.996	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.003	0.996	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.003	0.996	0.000
G73.1 Eaton-Lambert syndrome	0.003	0.996	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.003	0.996	0.000
G80 Infantile cerebral palsy	0.004	0.996	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.004	0.996	0.000
G58.9 Mononeuropathy, unspecified	0.003	0.996	0.000
G93 Other disorders of brain	0.004	0.996	0.000
G00.9 Bacterial meningitis, unspecified	0.003	0.996	0.000
G00.8 Other bacterial meningitis	0.003	0.996	0.000
G00.3 Staphylococcal meningitis	0.003	0.996	0.000
G00.2 Streptococcal meningitis	0.003	0.996	0.000
G00.1 Pneumococcal meningitis	0.003	0.996	0.000
G00.0 Haemophilus meningitis	0.003	0.996	0.000
G03.9 Meningitis, unspecified	0.003	0.996	0.000
G03.8 Meningitis due to other specified causes	0.003	0.996	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.003	0.996	0.000
G03.1 Chronic meningitis	0.003	0.996	0.000
G03.0 Nonpyogenic meningitis	0.003	0.996	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.003	0.996	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.003	0.996	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.003	0.996	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.003	0.996	0.000
G50.8 Other disorders of trigeminal nerve	0.003	0.996	0.000
G50.1 Atypical facial pain	0.003	0.996	0.000
G57.1 Meralgia paraesthetica	0.003	0.996	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.004	0.996	0.000
D12.3 Transverse colon	0.000	0.996	0.004
G60.0 Hereditary motor and sensory neuropathy	0.003	0.996	0.000
G58.8 Other specified mononeuropathies	0.003	0.996	0.000
G59.0 Diabetic mononeuropathy	0.003	0.996	0.000
G95.8 Other specified diseases of spinal cord	0.003	0.996	0.000
G95.0 Syringomyelia and syringobulbia	0.003	0.996	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.003	0.996	0.000
G21.9 Secondary Parkinsonism, unspecified	0.003	0.996	0.000
G21.8 Other secondary Parkinsonism	0.003	0.996	0.000
G21.4 Vascular parkinsonism	0.003	0.996	0.000
G21.3 Postencephalitic Parkinsonism	0.003	0.996	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.003	0.996	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.003	0.996	0.000
G21.0 Malignant neuroleptic syndrome	0.003	0.996	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.003	0.996	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.003	0.996	0.000
G23.3 Multiple system atrophy, cerebellar type	0.003	0.996	0.000
G23.2 Striatonigral degeneration	0.003	0.996	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.003	0.996	0.000
G23.0 Hallervorden-Spatz disease	0.003	0.996	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.003	0.996	0.000
G57.5 Tarsal tunnel syndrome	0.003	0.996	0.000
G57.4 Lesion of medial popliteal nerve	0.003	0.996	0.000
G57.3 Lesion of lateral popliteal nerve	0.003	0.996	0.000
G57.2 Lesion of femoral nerve	0.003	0.996	0.000
G57.0 Lesion of sciatic nerve	0.003	0.996	0.000
G62.8 Other specified polyneuropathies	0.003	0.996	0.000
G93.6 Cerebral oedema	0.003	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.003	0.997	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.003	0.997	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.003	0.997	0.000
G60.3 Idiopathic progressive neuropathy	0.003	0.997	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.003	0.997	0.000
G60.1 Refsum's disease	0.003	0.997	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.003	0.997	0.000
G30 Alzheimer's disease	0.003	0.997	0.000
G51.9 Disorder of facial nerve, unspecified	0.003	0.997	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.003	0.997	0.000
G61.8 Other inflammatory polyneuropathies	0.003	0.997	0.000
G51.8 Other disorders of facial nerve	0.003	0.997	0.000
G51.4 Facial myokymia	0.003	0.997	0.000
G51.3 Clonic hemifacial spasm	0.003	0.997	0.000
G51.2 Melkersson's syndrome	0.003	0.997	0.000
G51.1 Geniculate ganglionitis	0.003	0.997	0.000
G57.8 Other mononeuropathies of lower limb	0.003	0.997	0.000
G83.1 Monoplegia of lower limb	0.003	0.997	0.000
G12.2 Motor neuron disease	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
G96.9 Disorder of central nervous system, unspecified	0.003	0.997	0.000
G96.8 Other specified disorders of central nervous system	0.003	0.997	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.003	0.997	0.000
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.003	0.997	0.000
G61.1 Serum neuropathy	0.003	0.997	0.000
G90.8 Other disorders of autonomic nervous system	0.003	0.997	0.000
G90.4 Autonomic dysreflexia	0.003	0.997	0.000
G90.3 Multisystem degeneration	0.003	0.997	0.000
G90.2 Horner's syndrome	0.003	0.997	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.003	0.997	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.003	0.997	0.000
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
G12.9 Spinal muscular atrophy, unspecified	0.003	0.997	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.003	0.997	0.000
G12.1 Other inherited spinal muscular atrophy	0.003	0.997	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.003	0.997	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.003	0.997	0.000
G94.1 Hydrocephalus in neoplastic disease	0.003	0.997	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.003	0.997	0.000
G97.8 Other postprocedural disorders of nervous system	0.003	0.997	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.003	0.997	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.003	0.997	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.003	0.997	0.000
M81.98 Osteoporosis, unspecified (Other)	0.003	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.003	0.997	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.003	0.997	0.000
G83.9 Paralytic syndrome, unspecified	0.003	0.997	0.000
G83.8 Other specified paralytic syndromes	0.003	0.997	0.000
G83.5 Locked-in syndrome	0.003	0.997	0.000
G83.3 Monoplegia, unspecified	0.003	0.997	0.000
G83.2 Monoplegia of upper limb	0.003	0.997	0.000
G83.0 Diplegia of upper limbs	0.003	0.997	0.000
G62.2 Polyneuropathy due to other toxic agents	0.003	0.997	0.000
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
G62.0 Drug-induced polyneuropathy	0.003	0.997	0.000
G95.9 Disease of spinal cord, unspecified	0.003	0.997	0.000
G82.5 Tetraplegia, unspecified	0.003	0.997	0.000
G82.4 Spastic tetraplegia	0.003	0.997	0.000
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
G82.0 Flaccid paraplegia	0.003	0.997	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.003	0.997	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.003	0.997	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.997	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.003	0.997	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.003	0.997	0.000
G11.9 Hereditary ataxia, unspecified	0.003	0.997	0.000
G11.8 Other hereditary ataxias	0.003	0.997	0.000
G11.4 Hereditary spastic paraplegia	0.003	0.997	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.003	0.997	0.000
G11.2 Late-onset cerebellar ataxia	0.003	0.997	0.000
G11.1 Early-onset cerebellar ataxia	0.003	0.997	0.000
G11.0 Congenital nonprogressive ataxia	0.003	0.997	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.003	0.997	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.003	0.997	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.003	0.997	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.003	0.997	0.000
G91.8 Other hydrocephalus	0.003	0.997	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.003	0.997	0.000
G91.2 Normal-pressure hydrocephalus	0.003	0.997	0.000
G91.1 Obstructive hydrocephalus	0.003	0.997	0.000
G91.0 Communicating hydrocephalus	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
G93.0 Cerebral cysts	0.003	0.997	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.003	0.997	0.000
G61.0 Guillain-Barre syndrome	0.003	0.997	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.003	0.997	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.003	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.003	0.997	0.000
G80.8 Other infantile cerebral palsy	0.003	0.997	0.000
G80.4 Ataxic cerebral palsy	0.003	0.997	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.997	0.000
G80.2 Infantile hemiplegia	0.003	0.997	0.000
G80.1 Spastic diplegia	0.003	0.997	0.000
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.997	0.000
M23.3 Other meniscus derangements	0.003	0.997	0.000
G81 Hemiplegia	0.003	0.997	0.000
G93.7 Reye's syndrome	0.003	0.997	0.000
G93.5 Compression of brain	0.003	0.997	0.000
G93.4 Encephalopathy, unspecified	0.003	0.997	0.000
G93.2 Benign intracranial hypertension	0.003	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.003	0.997	0.000
N35.9 Urethral stricture, unspecified	0.000	0.997	0.003
B34.9 Viral infection, unspecified	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.000	0.997	0.003
M23.30 Other meniscus derangements (Multiple sites)	0.003	0.997	0.000
G91.9 Hydrocephalus, unspecified	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
G50.0 Trigeminal neuralgia	0.003	0.997	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.997	0.003
G55.2 Nerve root and plexus compressions in spondylosis	0.003	0.997	0.000
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
G30.8 Other Alzheimer's disease	0.002	0.997	0.000
G30.1 Alzheimer's disease with late onset	0.002	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.002	0.997	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.002	0.997	0.000
T39.0 Salicylates	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
K60.2 Anal fissure, unspecified	0.003	0.997	0.000
M54.22 Cervicalgia (Cervical region)	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.997	0.000
M81.8 Other osteoporosis	0.002	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.997	0.000
M81.5 Idiopathic osteoporosis	0.002	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.997	0.000
M81.2 Osteoporosis of disuse	0.002	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.997	0.000
G93.9 Disorder of brain, unspecified	0.002	0.997	0.000
G93.3 Postviral fatigue syndrome	0.002	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.002
C54.1 Endometrium	0.002	0.998	0.000
G57.6 Lesion of plantar nerve	0.002	0.998	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.002	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.000	0.998	0.002
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
M20.4 Other hammer toe(s) (acquired)	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
G36 Other acute disseminated demyelination	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.002	0.998	0.000
I12 Hypertensive renal disease	0.000	0.998	0.002
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
I77.5 Necrosis of artery	0.000	0.998	0.002
I77.4 Coeliac artery compression syndrome	0.000	0.998	0.002
I77.3 Arterial fibromuscular dysplasia	0.000	0.998	0.002
I77.2 Rupture of artery	0.000	0.998	0.002
I77.0 Arteriovenous fistula, acquired	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations