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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs141218484
log Bayes Factor = 0.0266478
Chromosome 11   position 62,248,663  (GRCh37) Explore rs141218484 on Ensembl!
Variant rs141218484 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.942 0.058
I25 Chronic ischaemic heart disease
0.000 0.943 0.057
I21.9 Acute myocardial infarction, unspecified
0.000 0.945 0.055
I20-I25 Ischaemic heart diseases
0.000 0.945 0.055
I21 Acute myocardial infarction
0.000 0.946 0.054
I25.2 Old myocardial infarction
0.000 0.953 0.047
I20 Angina pectoris
0.000 0.954 0.046
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.957 0.043
I22 Subsequent myocardial infarction
0.000 0.957 0.043
I20.0 Unstable angina
0.000 0.958 0.042
I24 Other acute ischaemic heart diseases
0.000 0.958 0.042
I21.4 Acute subendocardial myocardial infarction
0.000 0.958 0.041
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.959 0.041
I25.6 Silent myocardial ischaemia
0.000 0.959 0.041
I25.5 Ischaemic cardiomyopathy
0.000 0.959 0.041
I25.4 Coronary artery aneurysm
0.000 0.959 0.041
I25.3 Aneurysm of heart
0.000 0.959 0.041
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.959 0.041
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.960 0.040
I23 Certain current complications following acute myocardial infarction
0.000 0.961 0.039
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.961 0.039
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.961 0.039
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.966 0.034
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.966 0.034
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.966 0.034
I20.1 Angina pectoris with documented spasm
0.000 0.967 0.033
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.967 0.033
I24.8 Other forms of acute ischaemic heart disease
0.000 0.967 0.033
I20.8 Other forms of angina pectoris
0.000 0.969 0.031
I22.8 Subsequent myocardial infarction of other sites
0.000 0.969 0.031
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.969 0.031
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.969 0.031
I20.9 Angina pectoris, unspecified
0.000 0.969 0.031
I24.1 Dressler's syndrome
0.000 0.970 0.030
I23.8 Other current complications following acute myocardial infarction
0.000 0.971 0.028
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.971 0.028
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.971 0.028
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.971 0.028
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.971 0.028
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.971 0.028
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.971 0.028
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.971 0.028
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.973 0.027
Chapter IX Diseases of the circulatory system
0.000 0.991 0.009
I44.7 Left bundle-branch block, unspecified
0.000 0.992 0.008
I47 Paroxysmal tachycardia
0.000 0.992 0.008
I30-I52 Other forms of heart disease
0.000 0.992 0.008
I05-I09 Chronic rheumatic heart diseases
0.000 0.992 0.008
I44 Atrioventricular and left bundle-branch block
0.000 0.992 0.007
I47.1 Supraventricular tachycardia
0.000 0.993 0.007
R31 Unspecified haematuria
0.007 0.993 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.993 0.007
I47.2 Ventricular tachycardia
0.000 0.993 0.007
I08 Multiple valve diseases
0.000 0.993 0.007
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.993 0.006
I00-I02 Acute rheumatic fever
0.000 0.993 0.006
I60-I69 Cerebrovascular diseases
0.000 0.994 0.006
I34.0 Mitral (valve) insufficiency
0.000 0.994 0.006
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.994 0.006
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.994 0.006
I71 Aortic aneurysm and dissection
0.000 0.994 0.006
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.994 0.006
I44.1 Atrioventricular block, second degree
0.000 0.994 0.006
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.994 0.006
I47.0 Reentry ventricular arrhythmia
0.000 0.994 0.006
I50 Heart failure
0.000 0.994 0.006
I31 Other diseases of pericardium
0.000 0.994 0.006
I52 Other heart disorders in diseases classified elsewhere
0.000 0.994 0.006
I48 Atrial fibrillation and flutter
0.000 0.994 0.006
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.994 0.006
I41 Myocarditis in diseases classified elsewhere
0.000 0.994 0.006
I40 Acute myocarditis
0.000 0.994 0.006
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.994 0.006
I37 Pulmonary valve disorders
0.000 0.994 0.006
I36 Nonrheumatic tricuspid valve disorders
0.000 0.994 0.006
I32 Pericarditis in diseases classified elsewhere
0.000 0.994 0.006
I30 Acute pericarditis
0.000 0.994 0.006
I09 Other rheumatic heart diseases
0.000 0.994 0.006
I07 Rheumatic tricuspid valve diseases
0.000 0.994 0.006
I06 Rheumatic aortic valve diseases
0.000 0.994 0.006
I05 Rheumatic mitral valve diseases
0.000 0.994 0.006
I67 Other cerebrovascular diseases
0.000 0.994 0.006
I44.6 Other and unspecified fascicular block
0.000 0.994 0.006
I44.5 Left posterior fascicular block
0.000 0.994 0.006
I44.4 Left anterior fascicular block
0.000 0.994 0.006
I44.3 Other and unspecified atrioventricular block
0.000 0.994 0.006
I34.1 Mitral (valve) prolapse
0.000 0.994 0.006
I33 Acute and subacute endocarditis
0.000 0.994 0.005
R19.4 Change in bowel habit
0.000 0.994 0.006
I42 Cardiomyopathy
0.000 0.995 0.005
I51 Complications and ill-defined descriptions of heart disease
0.000 0.995 0.005
I50.1 Left ventricular failure
0.000 0.995 0.005
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.995 0.005
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.995 0.005
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.995 0.005
I27 Other pulmonary heart diseases
0.000 0.995 0.005
I08.9 Multiple valve disease, unspecified
0.000 0.995 0.005
I08.8 Other multiple valve diseases
0.000 0.995 0.005
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.995 0.005
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.995 0.005
I44.2 Atrioventricular block, complete
0.000 0.995 0.005
I08.0 Disorders of both mitral and aortic valves
0.000 0.995 0.005
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.995 0.005
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.995 0.005
I45 Other conduction disorders
0.000 0.995 0.005
I60 Subarachnoid haemorrhage
0.000 0.995 0.005
I67.8 Other specified cerebrovascular diseases
0.000 0.995 0.005
I02 Rheumatic chorea
0.000 0.995 0.005
I01 Rheumatic fever with heart involvement
0.000 0.995 0.005
I00 Rheumatic fever without mention of heart involvement
0.000 0.995 0.005
I69 Sequelae of cerebrovascular disease
0.000 0.995 0.005
I61 Intracerebral haemorrhage
0.000 0.995 0.005
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.995 0.005
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.995 0.005
I62 Other nontraumatic intracranial haemorrhage
0.000 0.995 0.005
I67.9 Cerebrovascular disease, unspecified
0.000 0.995 0.005
I35 Nonrheumatic aortic valve disorders
0.000 0.995 0.005
I70 Atherosclerosis
0.000 0.995 0.005
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.995 0.005
I72 Other aneurysm
0.000 0.995 0.005
I44.0 Atrioventricular block, first degree
0.000 0.995 0.005
I31.9 Disease of pericardium, unspecified
0.000 0.995 0.005
I28 Other diseases of pulmonary vessels
0.000 0.995 0.004
I38 Endocarditis, valve unspecified
0.000 0.995 0.004
I46 Cardiac arrest
0.000 0.995 0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.995 0.004
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.995 0.004
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.995 0.004
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.995 0.004
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.995 0.004
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.995 0.004
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.995 0.004
I71.0 Dissection of aorta [any part]
0.000 0.995 0.004
I27.0 Primary pulmonary hypertension
0.000 0.996 0.004
I31.8 Other specified diseases of pericardium
0.000 0.996 0.004
I31.2 Haemopericardium, not elsewhere classified
0.000 0.996 0.004
I31.1 Chronic constrictive pericarditis
0.000 0.996 0.004
I31.0 Chronic adhesive pericarditis
0.000 0.996 0.004
I67.1 Cerebral aneurysm, nonruptured
0.000 0.996 0.004
I30.9 Acute pericarditis, unspecified
0.000 0.996 0.004
I30.8 Other forms of acute pericarditis
0.000 0.996 0.004
I30.1 Infective pericarditis
0.000 0.996 0.004
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.996 0.004
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.996 0.004
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.996 0.004
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.996 0.004
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.996 0.004
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.996 0.004
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.996 0.004
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.996 0.004
I37.9 Pulmonary valve disorder, unspecified
0.000 0.996 0.004
I37.8 Other pulmonary valve disorders
0.000 0.996 0.004
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.996 0.004
I37.1 Pulmonary valve insufficiency
0.000 0.996 0.004
I37.0 Pulmonary valve stenosis
0.000 0.996 0.004
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.996 0.004
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.996 0.004
I40.9 Acute myocarditis, unspecified
0.000 0.996 0.004
I40.8 Other acute myocarditis
0.000 0.996 0.004
I40.1 Isolated myocarditis
0.000 0.996 0.004
I40.0 Infective myocarditis
0.000 0.996 0.004
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.996 0.004
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.996 0.004
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.996 0.004
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.996 0.004
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.996 0.004
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.996 0.004
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.996 0.004
I48.4 Atypical atrial flutter
0.000 0.996 0.004
I48.3 Typical atrial flutter
0.000 0.996 0.004
I48.2 Chronic atrial fibrillation
0.000 0.996 0.004
I48.1 Persistent atrial fibrillation
0.000 0.996 0.004
I48.0 Paroxysmal atrial fibrillation
0.000 0.996 0.004
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.996 0.004
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.996 0.004
I05.9 Mitral valve disease, unspecified
0.000 0.996 0.004
I05.8 Other mitral valve diseases
0.000 0.996 0.004
I05.2 Mitral stenosis with insufficiency
0.000 0.996 0.004
I05.1 Rheumatic mitral insufficiency
0.000 0.996 0.004
I05.0 Mitral stenosis
0.000 0.996 0.004
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.996 0.004
I06.8 Other rheumatic aortic valve diseases
0.000 0.996 0.004
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.996 0.004
I06.1 Rheumatic aortic insufficiency
0.000 0.996 0.004
I06.0 Rheumatic aortic stenosis
0.000 0.996 0.004
I07.9 Tricuspid valve disease, unspecified
0.000 0.996 0.004
I07.8 Other tricuspid valve diseases
0.000 0.996 0.004
I07.2 Tricuspid stenosis with insufficiency
0.000 0.996 0.004
I07.1 Tricuspid insufficiency
0.000 0.996 0.004
I07.0 Tricuspid stenosis
0.000 0.996 0.004
I09.9 Rheumatic heart disease, unspecified
0.000 0.996 0.004
I09.8 Other specified rheumatic heart diseases
0.000 0.996 0.004
I09.2 Chronic rheumatic pericarditis
0.000 0.996 0.004
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.996 0.004
I09.0 Rheumatic myocarditis
0.000 0.996 0.004
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.996 0.004
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.996 0.004
I67.5 Moyamoya disease
0.000 0.996 0.004
I67.4 Hypertensive encephalopathy
0.000 0.996 0.004
I67.3 Progressive vascular leukoencephalopathy
0.000 0.996 0.004
I67.2 Cerebral atherosclerosis
0.000 0.996 0.004
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.996 0.004
I78 Diseases of capillaries
0.000 0.996 0.004
I74 Arterial embolism and thrombosis
0.000 0.996 0.004
I33.9 Acute endocarditis, unspecified
0.000 0.996 0.004
I27.2 Other secondary pulmonary hypertension
0.000 0.996 0.004
I51.8 Other ill-defined heart diseases
0.000 0.996 0.004
I42.9 Cardiomyopathy, unspecified
0.000 0.996 0.004
I42.8 Other cardiomyopathies
0.000 0.996 0.004
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.996 0.004
I42.6 Alcoholic cardiomyopathy
0.000 0.996 0.004
I42.5 Other restrictive cardiomyopathy
0.000 0.996 0.004
I42.4 Endocardial fibroelastosis
0.000 0.996 0.004
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.996 0.004
I42.2 Other hypertrophic cardiomyopathy
0.000 0.996 0.004
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.996 0.004
I51.6 Cardiovascular disease, unspecified
0.000 0.996 0.004
I51.5 Myocardial degeneration
0.000 0.996 0.004
I51.4 Myocarditis, unspecified
0.000 0.996 0.004
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.996 0.004
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.996 0.004
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.996 0.004
I51.0 Cardiac septal defect, acquired
0.000 0.996 0.004
I31.3 Pericardial effusion (noninflammatory)
0.000 0.996 0.004
I77 Other disorders of arteries and arterioles
0.000 0.996 0.004
I73 Other peripheral vascular diseases
0.000 0.996 0.004
I51.9 Heart disease, unspecified
0.000 0.996 0.004
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.996 0.004
I27.9 Pulmonary heart disease, unspecified
0.000 0.996 0.004
I27.8 Other specified pulmonary heart diseases
0.000 0.996 0.004
I27.1 Kyphoscoliotic heart disease
0.000 0.996 0.004
I33.0 Acute and subacute infective endocarditis
0.000 0.996 0.004
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.996 0.004
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.996 0.004
I99 Other and unspecified disorders of circulatory system
0.000 0.996 0.004
I49 Other cardiac arrhythmias
0.000 0.996 0.004
I45.9 Conduction disorder, unspecified
0.000 0.996 0.004
I45.8 Other specified conduction disorders
0.000 0.996 0.004
I45.5 Other specified heart block
0.000 0.996 0.004
I45.4 Nonspecific intraventricular block
0.000 0.996 0.004
I45.3 Trifascicular block
0.000 0.996 0.004
I45.2 Bifascicular block
0.000 0.996 0.004
I45.0 Right fascicular block
0.000 0.996 0.004
I60.8 Other subarachnoid haemorrhage
0.000 0.996 0.004
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.996 0.004
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.996 0.004
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.996 0.004
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.996 0.004
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.996 0.004
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.996 0.004
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.996 0.004
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.996 0.004
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.996 0.004
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.996 0.004
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.996 0.004
I01.8 Other acute rheumatic heart disease
0.000 0.996 0.004
I01.2 Acute rheumatic myocarditis
0.000 0.996 0.004
I01.1 Acute rheumatic endocarditis
0.000 0.996 0.004
I01.0 Acute rheumatic pericarditis
0.000 0.996 0.004
I02.9 Rheumatic chorea without heart involvement
0.000 0.996 0.004
I02.0 Rheumatic chorea with heart involvement
0.000 0.996 0.004
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.996 0.004
I69.3 Sequelae of cerebral infarction
0.000 0.996 0.004
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.996 0.004
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.996 0.004
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.996 0.004
I50.0 Congestive heart failure
0.000 0.996 0.004
I42.0 Dilated cardiomyopathy
0.000 0.996 0.004
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.996 0.004
I61.8 Other intracerebral haemorrhage
0.000 0.996 0.004
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.996 0.004
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.996 0.004
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.996 0.004
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.996 0.004
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.996 0.004
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.996 0.004
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.996 0.004
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.996 0.003
I62.1 Nontraumatic extradural haemorrhage
0.000 0.996 0.003
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.996 0.003
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.996 0.003
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.996 0.003
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.996 0.003
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.996 0.003
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.996 0.003
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.996 0.003
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.996 0.003
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.996 0.003
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.996 0.003
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.003
I68.0 Cerebral amyloid angiopathy
0.000 0.996 0.003
I35.9 Aortic valve disorder, unspecified
0.000 0.996 0.004
I35.8 Other aortic valve disorders
0.000 0.996 0.004
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.996 0.004
I50.9 Heart failure, unspecified
0.000 0.996 0.004
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.996 0.003
I70.9 Generalised and unspecified atherosclerosis
0.000 0.996 0.003
I70.8 Atherosclerosis of other arteries
0.000 0.996 0.003
I70.1 Atherosclerosis of renal artery
0.000 0.996 0.003
I70.0 Atherosclerosis of aorta
0.000 0.996 0.003
L72.1 Trichilemmal cyst
0.004 0.996 0.000
I72.9 Aneurysm of unspecified site
0.000 0.996 0.003
I72.8 Aneurysm of other specified arteries
0.000 0.996 0.003
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.996 0.003
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.996 0.003
I72.4 Aneurysm of artery of lower extremity
0.000 0.996 0.003
I72.3 Aneurysm of iliac artery
0.000 0.996 0.003
I72.2 Aneurysm of renal artery
0.000 0.996 0.003
I72.1 Aneurysm of artery of upper extremity
0.000 0.996 0.003
I72.0 Aneurysm of carotid artery
0.000 0.996 0.003
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.996 0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.996 0.003
I79.1 Aortitis in diseases classified elsewhere
0.000 0.996 0.003
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.996 0.003
I10-I15 Hypertensive diseases
0.000 0.996 0.004
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.996 0.003
I28.8 Other specified diseases of pulmonary vessels
0.000 0.996 0.003
I28.1 Aneurysm of pulmonary artery
0.000 0.996 0.003
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.996 0.003
I51.7 Cardiomegaly
0.000 0.996 0.004
Z60.2 Living alone
0.000 0.996 0.004
I45.1 Other and unspecified right bundle-branch block
0.000 0.996 0.003
Y43.3 Other antineoplastic drugs
0.004 0.996 0.000
I46.1 Sudden cardiac death, so described
0.000 0.996 0.003
I45.6 Preexcitation syndrome
0.000 0.997 0.003
I26 Pulmonary embolism
0.000 0.997 0.003
I78.9 Disease of capillaries, unspecified
0.000 0.997 0.003
I78.8 Other diseases of capillaries
0.000 0.997 0.003
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.997 0.003
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.997 0.003
I74.8 Embolism and thrombosis of other arteries
0.000 0.997 0.003
I74.5 Embolism and thrombosis of iliac artery
0.000 0.997 0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.997 0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.997 0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.997 0.003
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.997 0.003
I63 Cerebral infarction
0.000 0.997 0.003
I35.1 Aortic (valve) insufficiency
0.000 0.997 0.003
I49.8 Other specified cardiac arrhythmias
0.000 0.997 0.003
I35.0 Aortic (valve) stenosis
0.000 0.997 0.003
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.997 0.003
I77.8 Other specified disorders of arteries and arterioles
0.000 0.997 0.003
I77.6 Arteritis, unspecified
0.000 0.997 0.003
I77.5 Necrosis of artery
0.000 0.997 0.003
I77.4 Coeliac artery compression syndrome
0.000 0.997 0.003
I77.3 Arterial fibromuscular dysplasia
0.000 0.997 0.003
I77.2 Rupture of artery
0.000 0.997 0.003
I77.0 Arteriovenous fistula, acquired
0.000 0.997 0.003
I73.9 Peripheral vascular disease, unspecified
0.000 0.997 0.003
I73.8 Other specified peripheral vascular diseases
0.000 0.997 0.003
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.997 0.003
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.997 0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.997 0.003
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.997 0.003
I97.1 Other functional disturbances following cardiac surgery
0.000 0.997 0.003
I97.0 Postcardiotomy syndrome
0.000 0.997 0.003
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.997 0.003
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.997 0.003
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.997 0.003
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
I98.0 Cardiovascular syphilis
0.000 0.997 0.003
I49.4 Other and unspecified premature depolarisation
0.000 0.997 0.003
I49.3 Ventricular premature depolarisation
0.000 0.997 0.003
I49.2 Junctional premature depolarisation
0.000 0.997 0.003
I46.9 Cardiac arrest, unspecified
0.000 0.997 0.003
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.997 0.003
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.997 0.003
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.997 0.003
I65.1 Occlusion and stenosis of basilar artery
0.000 0.997 0.003
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.997 0.003
Z72.0 Tobacco use
0.000 0.997 0.003
I46.0 Cardiac arrest with successful resuscitation
0.000 0.997 0.003
J43.9 Emphysema, unspecified
0.000 0.997 0.003
J44 Other chronic obstructive pulmonary disease
0.000 0.997 0.003
I78.1 Naevus, nonneoplastic
0.000 0.997 0.003
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.997 0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.997 0.003
I49.5 Sick sinus syndrome
0.000 0.997 0.003
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.997 0.003
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.997 0.003
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.997 0.003
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.997 0.003
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.997 0.003
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.997 0.003
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.997 0.003
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.997 0.003
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.997 0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.997 0.003
I15 Secondary hypertension
0.000 0.997 0.003
I13 Hypertensive heart and renal disease
0.000 0.997 0.003
I11 Hypertensive heart disease
0.000 0.997 0.003
J40 Bronchitis, not specified as acute or chronic
0.000 0.997 0.003
J43 Emphysema
0.000 0.997 0.003
Y43 Primarily systemic agents
0.003 0.997 0.000
H00.1 Chalazion
0.003 0.997 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.997 0.003
I49.1 Atrial premature depolarisation
0.000 0.997 0.002
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.997 0.003
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.997 0.002
K30 Dyspepsia
0.003 0.997 0.000
I49.0 Ventricular fibrillation and flutter
0.000 0.997 0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.997 0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.997 0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.997 0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.997 0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.997 0.002
I12 Hypertensive renal disease
0.000 0.997 0.003
I95 Hypotension
0.001 0.997 0.002
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.997 0.002
I77.1 Stricture of artery
0.000 0.997 0.002
Y84.8 Other medical procedures
0.002 0.997 0.000
I49.9 Cardiac arrhythmia, unspecified
0.000 0.998 0.002
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.998 0.002
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.998 0.002
I63.8 Other cerebral infarction
0.000 0.998 0.002
I73.0 Raynaud's syndrome
0.000 0.998 0.002
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.998 0.002
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.998 0.002
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.998 0.002
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.998 0.002
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.998 0.002
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.998 0.002
I15.9 Seconday hypertension, unspecified
0.000 0.998 0.002
I15.8 Other secondary hypertension
0.000 0.998 0.002
I15.2 Hypertension secondary to endocrine disorders
0.000 0.998 0.002
I15.1 Hypertension secondary to other renal disorders
0.000 0.998 0.002
I15.0 Renovascular hypertension
0.000 0.998 0.002
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.998 0.002
J47 Bronchiectasis
0.000 0.998 0.002
J43.8 Other emphysema
0.000 0.998 0.002
J43.2 Centrilobular emphysema
0.000 0.998 0.002
J43.1 Panlobular emphysema
0.000 0.998 0.002
J43.0 MacLeod's syndrome
0.000 0.998 0.002
Y43.9 Primarily systemic agent, unspecified
0.002 0.998 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.002 0.998 0.000
Y43.6 Enzymes, not elsewhere classified
0.002 0.998 0.000
Y43.5 Acidifying and alkalising agents
0.002 0.998 0.000
Y43.4 Immunosuppressive agents
0.002 0.998 0.000
Y43.2 Antineoplastic natural products
0.002 0.998 0.000
Y43.1 Antineoplastic antimetabolites
0.002 0.998 0.000
Y43.0 Antiallergic and antiemetic drugs
0.002 0.998 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.998 0.002
J46 Status asthmaticus
0.000 0.998 0.002
J42 Unspecified chronic bronchitis
0.000 0.998 0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.002 0.998 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.000 0.998 0.002
I12.9 Hypertensive renal disease without renal failure
0.000 0.998 0.002
I95.8 Other hypotension
0.001 0.998 0.002
I95.2 Hypotension due to drugs
0.001 0.998 0.002
I95.0 Idiopathic hypotension
0.001 0.998 0.002
I65.2 Occlusion and stenosis of carotid artery
0.001 0.998 0.002
J45 Asthma
0.000 0.998 0.002
N41.1 Chronic prostatitis
0.002 0.998 0.000
Z60 Problems related to social environment
0.000 0.998 0.002
I63.9 Cerebral infarction, unspecified
0.000 0.998 0.002
H00 Hordeolum and chalazion
0.002 0.998 0.000
Y40 Systemic antibiotics
0.002 0.998 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.002 0.998 0.000
Y57 Other and unspecified drugs and medicaments
0.002 0.998 0.000
Y44 Agents primarily affecting blood constituents
0.002 0.998 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.002 0.998 0.000
Y40.0 Penicillins
0.002 0.998 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.998 0.002
R20.2 Paraesthesia of skin
0.000 0.998 0.002
E87.5 Hyperkalaemia
0.002 0.998 0.000
H01.0 Blepharitis
0.002 0.998 0.000
I95.1 Orthostatic hypotension
0.001 0.998 0.001
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.998 0.002
J41.1 Mucopurulent chronic bronchitis
0.000 0.998 0.002
J41.0 Simple chronic bronchitis
0.000 0.998 0.002
Y59 Other and unspecified vaccines and biological substances
0.002 0.998 0.000
Y58 Bacterial vaccines
0.002 0.998 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.002 0.998 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.002 0.998 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.002 0.998 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.002 0.998 0.000
Y52 Agents primarily affecting the cardiovascular system
0.002 0.998 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.002 0.998 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.002 0.998 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.002 0.998 0.000
Y48 Anaesthetics and therapeutic gases
0.002 0.998 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.002 0.998 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.002 0.998 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.002 0.998 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.002 0.998 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.002 0.998 0.000
E87.6 Hypokalaemia
0.002 0.998 0.000
J45.8 Mixed asthma
0.000 0.998 0.002
J45.1 Nonallergic asthma
0.000 0.998 0.002
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.002 0.998 0.000
Y57.9 Drug or medicament, unspecified
0.002 0.998 0.000
Z60.9 Problem related to social environment, unspecified
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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