TreeWAS – Variant ID: rs141668138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I47.1 Supraventricular tachycardia	0.036	0.964	0.000
I47 Paroxysmal tachycardia	0.032	0.968	0.000
I30-I52 Other forms of heart disease	0.031	0.969	0.000
I42 Cardiomyopathy	0.030	0.970	0.000
I44 Atrioventricular and left bundle-branch block	0.028	0.972	0.000
I31 Other diseases of pericardium	0.028	0.972	0.000
I50 Heart failure	0.026	0.974	0.000
I47.0 Reentry ventricular arrhythmia	0.026	0.974	0.000
I42.9 Cardiomyopathy, unspecified	0.026	0.974	0.000
I45 Other conduction disorders	0.026	0.974	0.000
I31.9 Disease of pericardium, unspecified	0.025	0.975	0.000
I50.0 Congestive heart failure	0.025	0.975	0.000
I42.0 Dilated cardiomyopathy	0.025	0.975	0.000
I42.8 Other cardiomyopathies	0.024	0.976	0.000
I51 Complications and ill-defined descriptions of heart disease	0.024	0.976	0.000
I44.7 Left bundle-branch block, unspecified	0.024	0.976	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.024	0.976	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.023	0.977	0.000
I44.0 Atrioventricular block, first degree	0.023	0.977	0.000
I42.2 Other hypertrophic cardiomyopathy	0.022	0.977	0.000
I38 Endocarditis, valve unspecified	0.022	0.978	0.000
I52 Other heart disorders in diseases classified elsewhere	0.022	0.978	0.000
I48 Atrial fibrillation and flutter	0.022	0.978	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.022	0.978	0.000
I41 Myocarditis in diseases classified elsewhere	0.022	0.978	0.000
I40 Acute myocarditis	0.022	0.978	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.022	0.978	0.000
I37 Pulmonary valve disorders	0.022	0.978	0.000
I36 Nonrheumatic tricuspid valve disorders	0.022	0.978	0.000
I32 Pericarditis in diseases classified elsewhere	0.022	0.978	0.000
I30 Acute pericarditis	0.022	0.978	0.000
I46 Cardiac arrest	0.022	0.978	0.000
I33 Acute and subacute endocarditis	0.021	0.978	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.021	0.978	0.000
I42.6 Alcoholic cardiomyopathy	0.021	0.978	0.000
I42.5 Other restrictive cardiomyopathy	0.021	0.978	0.000
I42.4 Endocardial fibroelastosis	0.021	0.978	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.021	0.978	0.000
I44.1 Atrioventricular block, second degree	0.021	0.979	0.000
I31.3 Pericardial effusion (noninflammatory)	0.021	0.979	0.000
I44.2 Atrioventricular block, complete	0.020	0.979	0.000
I44.6 Other and unspecified fascicular block	0.020	0.980	0.000
I44.5 Left posterior fascicular block	0.020	0.980	0.000
I44.4 Left anterior fascicular block	0.020	0.980	0.000
I44.3 Other and unspecified atrioventricular block	0.020	0.980	0.000
I31.8 Other specified diseases of pericardium	0.020	0.980	0.000
I31.2 Haemopericardium, not elsewhere classified	0.020	0.980	0.000
I31.1 Chronic constrictive pericarditis	0.020	0.980	0.000
I31.0 Chronic adhesive pericarditis	0.020	0.980	0.000
I51.9 Heart disease, unspecified	0.020	0.980	0.000
I45.1 Other and unspecified right bundle-branch block	0.020	0.980	0.000
I50.9 Heart failure, unspecified	0.020	0.980	0.000
I45.5 Other specified heart block	0.020	0.980	0.000
I45.6 Preexcitation syndrome	0.019	0.980	0.000
I45.9 Conduction disorder, unspecified	0.019	0.981	0.000
I51.8 Other ill-defined heart diseases	0.019	0.981	0.000
I45.8 Other specified conduction disorders	0.018	0.981	0.000
I45.4 Nonspecific intraventricular block	0.018	0.981	0.000
I45.3 Trifascicular block	0.018	0.981	0.000
I45.2 Bifascicular block	0.018	0.981	0.000
I45.0 Right fascicular block	0.018	0.981	0.000
I51.6 Cardiovascular disease, unspecified	0.018	0.982	0.000
I51.5 Myocardial degeneration	0.018	0.982	0.000
I51.4 Myocarditis, unspecified	0.018	0.982	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.018	0.982	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.018	0.982	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.018	0.982	0.000
I51.0 Cardiac septal defect, acquired	0.018	0.982	0.000
I35 Nonrheumatic aortic valve disorders	0.016	0.983	0.000
I30.9 Acute pericarditis, unspecified	0.016	0.984	0.000
I30.8 Other forms of acute pericarditis	0.016	0.984	0.000
I30.1 Infective pericarditis	0.016	0.984	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.016	0.984	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.016	0.984	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.016	0.984	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.016	0.984	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.016	0.984	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.016	0.984	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.016	0.984	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.016	0.984	0.000
I37.9 Pulmonary valve disorder, unspecified	0.016	0.984	0.000
I37.8 Other pulmonary valve disorders	0.016	0.984	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.016	0.984	0.000
I37.1 Pulmonary valve insufficiency	0.016	0.984	0.000
I37.0 Pulmonary valve stenosis	0.016	0.984	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.016	0.984	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I40.9 Acute myocarditis, unspecified	0.016	0.984	0.000
I40.8 Other acute myocarditis	0.016	0.984	0.000
I40.1 Isolated myocarditis	0.016	0.984	0.000
I40.0 Infective myocarditis	0.016	0.984	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.016	0.984	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.016	0.984	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.016	0.984	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.016	0.984	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.016	0.984	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.016	0.984	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.016	0.984	0.000
I48.4 Atypical atrial flutter	0.016	0.984	0.000
I48.3 Typical atrial flutter	0.016	0.984	0.000
I48.2 Chronic atrial fibrillation	0.016	0.984	0.000
I48.1 Persistent atrial fibrillation	0.016	0.984	0.000
I48.0 Paroxysmal atrial fibrillation	0.016	0.984	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.016	0.984	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.016	0.984	0.000
I46.0 Cardiac arrest with successful resuscitation	0.016	0.984	0.000
I46.1 Sudden cardiac death, so described	0.016	0.984	0.000
I33.9 Acute endocarditis, unspecified	0.016	0.984	0.000
I46.9 Cardiac arrest, unspecified	0.015	0.984	0.000
I33.0 Acute and subacute infective endocarditis	0.015	0.985	0.000
I51.7 Cardiomegaly	0.015	0.985	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.985	0.015
I47.2 Ventricular tachycardia	0.013	0.986	0.000
I34 Nonrheumatic mitral valve disorders	0.013	0.987	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.013	0.987	0.000
I35.9 Aortic valve disorder, unspecified	0.012	0.988	0.000
I35.8 Other aortic valve disorders	0.012	0.988	0.000
I35.0 Aortic (valve) stenosis	0.011	0.989	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.010	0.990	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.010	0.990	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.010	0.990	0.000
M81.9 Osteoporosis, unspecified	0.000	0.990	0.010
I49 Other cardiac arrhythmias	0.009	0.991	0.000
I50.1 Left ventricular failure	0.009	0.991	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.992	0.008
I34.1 Mitral (valve) prolapse	0.008	0.992	0.000
H35.3 Degeneration of macula and posterior pole	0.007	0.993	0.000
I49.1 Atrial premature depolarisation	0.007	0.993	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.993	0.007
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.993	0.007
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.993	0.007
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.993	0.007
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.993	0.007
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.993	0.007
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.993	0.007
I35.1 Aortic (valve) insufficiency	0.007	0.993	0.001
I49.4 Other and unspecified premature depolarisation	0.007	0.993	0.000
I49.2 Junctional premature depolarisation	0.007	0.993	0.000
H35 Other retinal disorders	0.007	0.993	0.000
N39.3 Stress incontinence	0.000	0.993	0.007
H35.8 Other specified retinal disorders	0.007	0.993	0.000
I49.5 Sick sinus syndrome	0.006	0.994	0.000
I49.0 Ventricular fibrillation and flutter	0.006	0.994	0.000
H52.1 Myopia	0.006	0.994	0.000
H35.7 Separation of retinal layers	0.006	0.994	0.000
I49.9 Cardiac arrhythmia, unspecified	0.005	0.994	0.000
I49.8 Other specified cardiac arrhythmias	0.005	0.994	0.000
H52 Disorders of refraction and accommodation	0.005	0.995	0.000
I34.0 Mitral (valve) insufficiency	0.005	0.995	0.000
H35.4 Peripheral retinal degeneration	0.005	0.995	0.000
H35.9 Retinal disorder, unspecified	0.005	0.995	0.000
H35.6 Retinal haemorrhage	0.005	0.995	0.000
H35.5 Hereditary retinal dystrophy	0.005	0.995	0.000
H35.2 Other proliferative retinopathy	0.005	0.995	0.000
H35.1 Retinopathy of prematurity	0.005	0.995	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.005	0.995	0.000
H30-H36 Disorders of choroid and retina	0.005	0.995	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.005	0.995	0.000
I49.3 Ventricular premature depolarisation	0.004	0.995	0.001
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.995	0.000
J32.0 Chronic maxillary sinusitis	0.005	0.995	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.000	0.995	0.004
J32 Chronic sinusitis	0.005	0.995	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.005	0.995	0.000
H35.0 Background retinopathy and retinal vascular changes	0.004	0.995	0.000
H50 Other strabismus	0.004	0.995	0.000
H52.3 Anisometropia and aniseikonia	0.004	0.996	0.000
J32.9 Chronic sinusitis, unspecified	0.004	0.996	0.000
J32.8 Other chronic sinusitis	0.004	0.996	0.000
H34 Retinal vascular occlusions	0.004	0.996	0.000
H36 Retinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H52.7 Disorder of refraction, unspecified	0.004	0.996	0.000
H52.6 Other disorders of refraction	0.004	0.996	0.000
H52.5 Disorders of accommodation	0.004	0.996	0.000
H52.4 Presbyopia	0.004	0.996	0.000
J32.2 Chronic ethmoidal sinusitis	0.004	0.996	0.000
H52.2 Astigmatism	0.004	0.996	0.000
H49 Paralytic strabismus	0.004	0.996	0.000
Chapter VII Diseases of the eye and adnexa	0.004	0.996	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H31 Other disorders of choroid	0.004	0.996	0.000
H30 Chorioretinal inflammation	0.004	0.996	0.000
H50.1 Divergent concomitant strabismus	0.004	0.996	0.000
H52.0 Hypermetropia	0.004	0.996	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
H51 Other disorders of binocular movement	0.004	0.996	0.000
H50.9 Strabismus, unspecified	0.004	0.996	0.000
F17.1 Harmful use	0.000	0.996	0.004
J32.4 Chronic pansinusitis	0.004	0.996	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
H20 Iridocyclitis	0.004	0.996	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.003	0.996	0.000
M81.8 Other osteoporosis	0.000	0.996	0.003
M81.6 Localised osteoporosis [Lequesne]	0.000	0.996	0.003
M81.5 Idiopathic osteoporosis	0.000	0.996	0.003
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.996	0.003
M81.2 Osteoporosis of disuse	0.000	0.996	0.003
M81.1 Postoophorectomy osteoporosis	0.000	0.996	0.003
M81.0 Postmenopausal osteoporosis	0.000	0.996	0.003
H50.0 Convergent concomitant strabismus	0.003	0.996	0.000
J32.3 Chronic sphenoidal sinusitis	0.003	0.996	0.000
J32.1 Chronic frontal sinusitis	0.003	0.996	0.000
H34.8 Other retinal vascular occlusions	0.003	0.996	0.000
H55-H59 Other disorders of eye and adnexa	0.003	0.996	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.996	0.003
H36.0 Diabetic retinopathy	0.003	0.996	0.000
H50.8 Other specified strabismus	0.003	0.996	0.000
H50.6 Mechanical strabismus	0.003	0.996	0.000
H50.5 Heterophoria	0.003	0.996	0.000
H50.4 Other and unspecified heterotropia	0.003	0.996	0.000
H50.3 Intermittent heterotropia	0.003	0.996	0.000
H50.2 Vertical strabismus	0.003	0.996	0.000
H43-H45 Disorders of vitreous body and globe	0.003	0.997	0.000
F10.2 Dependence syndrome	0.000	0.997	0.003
H20.8 Other iridocyclitis	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.000	0.997	0.003
H46-H48 Disorders of optic nerve and visual pathways	0.003	0.997	0.000
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
H34.9 Retinal vascular occlusion, unspecified	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
H34.1 Central retinal artery occlusion	0.003	0.997	0.000
H34.0 Transient retinal artery occlusion	0.003	0.997	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
H49.9 Paralytic strabismus, unspecified	0.003	0.997	0.000
H49.8 Other paralytic strabismus	0.003	0.997	0.000
H49.4 Progressive external ophthalmoplegia	0.003	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.003	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.003	0.997	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
H30.9 Chorioretinal inflammation, unspecified	0.003	0.997	0.000
H30.8 Other chorioretinal inflammations	0.003	0.997	0.000
H30.2 Posterior cyclitis	0.003	0.997	0.000
H30.1 Disseminated chorioretinal inflammation	0.003	0.997	0.000
H30.0 Focal chorioretinal inflammation	0.003	0.997	0.000
H31.9 Disorder of choroid, unspecified	0.003	0.997	0.000
H31.8 Other specified disorders of choroid	0.003	0.997	0.000
H31.4 Choroidal detachment	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.003	0.997	0.000
H31.2 Hereditary choroidal dystrophy	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.003	0.997	0.000
H31.0 Chorioretinal scars	0.003	0.997	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.003	0.997	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.003	0.997	0.000
M25.7 Osteophyte	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
H15 Disorders of sclera	0.003	0.997	0.000
H51.9 Disorder of binocular movement, unspecified	0.003	0.997	0.000
H51.8 Other specified disorders of binocular movement	0.003	0.997	0.000
H51.2 Internuclear ophthalmoplegia	0.003	0.997	0.000
H51.1 Convergence insufficiency and excess	0.003	0.997	0.000
H51.0 Palsy of conjugate gaze	0.003	0.997	0.000
H43 Disorders of vitreous body	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
H44 Disorders of globe	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.997	0.000
M25 Other joint disorders, not elsewhere classified	0.003	0.997	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.997	0.003
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.997	0.003
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.997	0.003
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.997	0.003
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.997	0.003
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.997	0.003
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.997	0.003
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.997	0.003
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.997	0.003
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.997	0.003
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.997	0.003
M81.28 Osteoporosis of disuse (Other)	0.000	0.997	0.003
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.997	0.003
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.997	0.003
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.997	0.003
M81.24 Osteoporosis of disuse (Hand)	0.000	0.997	0.003
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.997	0.003
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.997	0.003
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.997	0.003
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.997	0.003
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.997	0.003
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.997	0.003
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.997	0.003
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.997	0.003
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.58 Idiopathic osteoporosis (Other)	0.000	0.997	0.003
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.997	0.003
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.997	0.003
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.997	0.003
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.997	0.003
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.997	0.003
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.997	0.003
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.997	0.003
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.997	0.003
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.997	0.003
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.997	0.003
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.997	0.003
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.997	0.003
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.997	0.003
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.997	0.003
M81.89 Other osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.88 Other osteoporosis (Other)	0.000	0.997	0.003
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.86 Other osteoporosis (Lower leg)	0.000	0.997	0.003
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.84 Other osteoporosis (Hand)	0.000	0.997	0.003
M81.83 Other osteoporosis (Forearm)	0.000	0.997	0.003
M81.82 Other osteoporosis (Upper arm)	0.000	0.997	0.003
M81.81 Other osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.80 Other osteoporosis (Multiple sites)	0.000	0.997	0.003
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.997	0.003
H33 Retinal detachments and breaks	0.003	0.997	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.003	0.997	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.003	0.997	0.000
M23 Internal derangement of knee	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.003	0.997	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.997	0.003
H46 Optic neuritis	0.003	0.997	0.000
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.997	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.997	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.997	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.997	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.997	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.997	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.997	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.997	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.997	0.002
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.002	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.997	0.000
H18.7 Other corneal deformities	0.002	0.997	0.000
H18.6 Keratoconus	0.002	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.997	0.000
H18.4 Corneal degeneration	0.002	0.997	0.000
H18.3 Changes in corneal membranes	0.002	0.997	0.000
H18.2 Other corneal oedema	0.002	0.997	0.000
H18.1 Bullous keratopathy	0.002	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.997	0.000
H53 Visual disturbances	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
H44.2 Degenerative myopia	0.002	0.997	0.000
M79.0 Rheumatism, unspecified	0.000	0.997	0.003
M25.9 Joint disorder, unspecified	0.002	0.997	0.000
M25.4 Effusion of joint	0.002	0.997	0.000
F10.3 Withdrawal state	0.000	0.997	0.002
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.997	0.000
H59.0 Vitreous syndrome following cataract surgery	0.002	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.997	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.997	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.997	0.000
H16.0 Corneal ulcer	0.002	0.997	0.000
W19.9 Unspecified place	0.002	0.997	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.002	0.997	0.000
H10 Conjunctivitis	0.002	0.997	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
M25.73 Osteophyte (Forearm)	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.002	0.998	0.000
M25.70 Osteophyte (Multiple sites)	0.002	0.998	0.000
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
H11 Other disorders of conjunctiva	0.002	0.998	0.000
M22 Disorders of patella	0.002	0.998	0.000
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
H43.0 Vitreous prolapse	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
H44.9 Disorder of globe, unspecified	0.002	0.998	0.000
H44.8 Other disorders of globe	0.002	0.998	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.002	0.998	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.002	0.998	0.000
H44.5 Degenerated conditions of globe	0.002	0.998	0.000
H44.4 Hypotony of eye	0.002	0.998	0.000
H44.3 Other degenerative disorders of globe	0.002	0.998	0.000
H44.1 Other endophthalmitis	0.002	0.998	0.000
H44.0 Purulent endophthalmitis	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
M25.3 Other instability of joint	0.002	0.998	0.000
M25.2 Flail joint	0.002	0.998	0.000
M25.1 Fistula of joint	0.002	0.998	0.000
M25.0 Haemarthrosis	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
H33.3 Retinal breaks without detachment	0.002	0.998	0.000
H40-H42 Glaucoma	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
F17.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F17.8 Other mental and behavioural disorders	0.000	0.998	0.002
F17.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F17.6 Amnesic syndrome	0.000	0.998	0.002
F17.5 Psychotic disorder	0.000	0.998	0.002
F17.4 Withdrawal state with delirium	0.000	0.998	0.002
F17.3 Withdrawal state	0.000	0.998	0.002
F17.0 Acute intoxication	0.000	0.998	0.002
H33.5 Other retinal detachments	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.002	0.998	0.000
H47.6 Disorders of visual cortex	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.002	0.998	0.000
H47.4 Disorders of optic chiasm	0.002	0.998	0.000
H47.2 Optic atrophy	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations