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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1419637
log Bayes Factor = 57.0183
Chromosome 6   position 29,355,558  (GRCh37) Explore rs1419637 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.012 0.988
E10.2 With renal complications
0.000 0.014 0.986
E20-E35 Disorders of other endocrine glands
0.000 0.014 0.986
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.018 0.982
E03 Other hypothyroidism
0.000 0.021 0.979
E27 Other disorders of adrenal gland
0.000 0.025 0.975
E03.9 Hypothyroidism, unspecified
0.000 0.036 0.964
E27.1 Primary adrenocortical insufficiency
0.000 0.045 0.955
E10.1 With ketoacidosis
0.000 0.059 0.941
E24 Cushing's syndrome
0.000 0.062 0.938
E13 Other specified diabetes mellitus
0.000 0.066 0.934
E14.9 Without complications
0.000 0.072 0.928
E10.4 With neurological complications
0.000 0.109 0.891
E13.9 Without complications
0.000 0.111 0.889
E20 Hypoparathyroidism
0.000 0.133 0.867
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.144 0.856
E10.0 With coma
0.000 0.147 0.853
E50-E64 Other nutritional deficiencies
0.000 0.148 0.852
E24.9 Cushing's syndrome, unspecified
0.000 0.157 0.843
E14.6 With other specified complications
0.000 0.165 0.835
K90 Intestinal malabsorption
0.000 0.175 0.825
E14.2 Withrenal complications
0.000 0.194 0.805
E27.8 Other specified disorders of adrenal gland
0.000 0.198 0.802
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.202 0.798
E40-E46 Malnutrition
0.000 0.210 0.790
E24.2 Drug-induced Cushing's syndrome
0.000 0.215 0.785
E20.9 Hypoparathyroidism, unspecified
0.000 0.218 0.782
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.226 0.774
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.226 0.774
E24.0 Pituitary-dependent Cushing's disease
0.000 0.228 0.772
K90.9 Intestinal malabsorption, unspecified
0.000 0.230 0.770
E16 Other disorders of pancreatic internal secretion
0.000 0.246 0.754
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.259 0.741
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.272 0.728
E05.8 Other thyrotoxicosis
0.000 0.274 0.726
E10.6 With other specified complications
0.000 0.278 0.721
E61 Deficiency of other nutrient elements
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.284 0.715
E14.0 With coma
0.000 0.284 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E14.5 With peripheral circulatory complications
0.000 0.288 0.712
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.293 0.707
E32 Diseases of thymus
0.000 0.293 0.707
E30 Disorders of puberty, not elsewhere classified
0.000 0.293 0.707
E03.5 Myxoedema coma
0.000 0.298 0.702
E03.4 Atrophy of thyroid (acquired)
0.000 0.298 0.702
E03.3 Postinfectious hypothyroidism
0.000 0.298 0.702
E31 Polyglandular dysfunction
0.000 0.299 0.701
E55 Vitamin D deficiency
0.000 0.299 0.701
E27.5 Adrenomedullary hyperfunction
0.000 0.301 0.699
E27.0 Other adrenocortical overactivity
0.000 0.301 0.699
E25 Adrenogenital disorders
0.000 0.304 0.696
E27.9 Disorder of adrenal gland, unspecified
0.000 0.305 0.694
E03.8 Other specified hypothyroidism
0.000 0.306 0.694
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.309 0.691
E51 Thiamine deficiency
0.000 0.311 0.689
E14.4 With neurological complications
0.000 0.317 0.683
E29 Testicular dysfunction
0.000 0.324 0.676
E24.8 Other Cushing's syndrome
0.000 0.328 0.672
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.328 0.672
E24.3 Ectopic ACTH syndrome
0.000 0.328 0.672
E24.1 Nelson's syndrome
0.000 0.328 0.672
E13.8 With unspecified complications
0.000 0.331 0.669
E13.7 With multiple complications
0.000 0.331 0.669
E13.6 With other specified complications
0.000 0.331 0.669
E13.5 With peripheral circulatory complications
0.000 0.331 0.669
E13.4 With neurological complications
0.000 0.331 0.669
E13.2 With renal complications
0.000 0.331 0.669
E13.1 With ketoacidosis
0.000 0.331 0.669
E13.0 With coma
0.000 0.331 0.669
E14.1 With ketoacidosis
0.000 0.336 0.664
E14.8 With unspecified complications
0.000 0.345 0.655
E10.8 With unspecified complications
0.000 0.345 0.655
E23 Hypofunction and other disorders of pituitary gland
0.000 0.347 0.653
E13.3 With ophthalmic complications
0.000 0.351 0.649
E03.1 Congenital hypothyroidism without goitre
0.000 0.356 0.644
E16.2 Hypoglycaemia, unspecified
0.000 0.359 0.641
E46 Unspecified protein-energy malnutrition
0.000 0.360 0.640
E22 Hyperfunction of pituitary gland
0.000 0.361 0.639
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.370 0.630
E56 Other vitamin deficiencies
0.000 0.371 0.629
E27.2 Addisonian crisis
0.000 0.374 0.626
E28 Ovarian dysfunction
0.000 0.376 0.624
E20.8 Other hypoparathyroidism
0.000 0.378 0.622
E20.1 Pseudohypoparathyroidism
0.000 0.378 0.622
E20.0 Idiopathic hypoparathyroidism
0.000 0.378 0.622
E15 Nondiabetic hypoglycaemic coma
0.000 0.386 0.614
E61.2 Magnesium deficiency
0.000 0.387 0.613
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.389 0.611
E50 Vitamin A deficiency
0.000 0.389 0.611
E60 Dietary zinc deficiency
0.000 0.389 0.611
E59 Dietary selenium deficiency
0.000 0.389 0.611
E52 Niacin deficiency [pellagra]
0.000 0.389 0.611
E07 Other disorders of thyroid
0.000 0.391 0.609
E53 Deficiency of other B group vitamins
0.000 0.397 0.602
E58 Dietary calcium deficiency
0.000 0.401 0.598
E55.9 Vitamin D deficiency, unspecified
0.000 0.407 0.593
K90.3 Pancreatic steatorrhoea
0.000 0.408 0.591
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.408 0.591
K90.1 Tropical sprue
0.000 0.408 0.591
E06 Thyroiditis
0.000 0.411 0.589
E10.5 With peripheral circulatory complications
0.000 0.414 0.586
E16.1 Other hypoglycaemia
0.000 0.415 0.585
E26 Hyperaldosteronism
0.000 0.415 0.584
E34 Other endocrine disorders
0.000 0.419 0.581
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.422 0.578
E51.2 Wernicke's encephalopathy
0.000 0.428 0.572
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.433 0.566
E45 Retarded development following protein-energy malnutrition
0.000 0.433 0.566
E43 Unspecified severe protein-energy malnutrition
0.000 0.433 0.566
E42 Marasmic kwashiorkor
0.000 0.433 0.566
E41 Nutritional marasmus
0.000 0.433 0.566
E40 Kwashiorkor
0.000 0.433 0.566
E22.0 Acromegaly and pituitary gigantism
0.000 0.449 0.551
E53.9 Vitamin B deficiency, unspecified
0.000 0.451 0.549
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.460 0.540
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.460 0.540
E16.4 Abnormal secretion of gastrin
0.000 0.460 0.540
E16.3 Increased secretion of glucagon
0.000 0.460 0.540
E61.1 Iron deficiency
0.000 0.462 0.538
K90.8 Other intestinal malabsorption
0.000 0.463 0.536
E63 Other nutritional deficiencies
0.000 0.464 0.536
E23.2 Diabetes insipidus
0.000 0.474 0.526
E61.9 Deficiency of nutrient element, unspecified
0.000 0.484 0.516
E61.8 Deficiency of other specified nutrient elements
0.000 0.484 0.516
E61.7 Deficiency of multiple nutrient elements
0.000 0.484 0.516
E61.6 Vanadium deficiency
0.000 0.484 0.516
E61.5 Molybdenum deficiency
0.000 0.484 0.516
E61.4 Chromium deficiency
0.000 0.484 0.516
E61.3 Manganese deficiency
0.000 0.484 0.516
E61.0 Copper deficiency
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E30.9 Disorder of puberty, unspecified
0.000 0.493 0.507
E30.8 Other disorders of puberty
0.000 0.493 0.507
E30.1 Precocious puberty
0.000 0.493 0.507
E30.0 Delayed puberty
0.000 0.493 0.507
E32.9 Disease of thymus, unspecified
0.000 0.493 0.507
E32.8 Other diseases of thymus
0.000 0.493 0.507
E32.1 Abscess of thymus
0.000 0.493 0.507
E32.0 Persistent hyperplasia of thymus
0.000 0.493 0.507
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.493 0.507
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.493 0.507
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.493 0.507
E54 Ascorbic acid deficiency
0.000 0.494 0.506
E31.9 Polyglandular dysfunction, unspecified
0.000 0.497 0.503
E31.8 Other polyglandular dysfunction
0.000 0.497 0.503
E31.1 Polyglandular hyperfunction
0.000 0.497 0.503
E55.0 Rickets, active
0.000 0.497 0.503
E23.0 Hypopituitarism
0.000 0.499 0.501
E25.9 Adrenogenital disorder, unspecified
0.000 0.501 0.499
E25.8 Other adrenogenital disorders
0.000 0.501 0.499
E31.0 Autoimmune polyglandular failure
0.000 0.502 0.498
E51.9 Thiamine deficiency, unspecified
0.000 0.506 0.494
E51.8 Other manifestations of thiamine deficiency
0.000 0.506 0.494
E51.1 Beriberi
0.000 0.506 0.494
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.512 0.488
E29.9 Testicular dysfunction, unspecified
0.000 0.515 0.485
E29.8 Other testicular dysfunction
0.000 0.515 0.485
E29.0 Testicular hyperfunction
0.000 0.515 0.485
E22.1 Hyperprolactinaemia
0.000 0.528 0.472
E56.1 Deficiency of vitamin K
0.000 0.531 0.469
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.532 0.468
E23.1 Drug-induced hypopituitarism
0.000 0.532 0.468
E06.9 Thyroiditis, unspecified
0.000 0.534 0.466
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.539 0.461
E22.8 Other hyperfunction of pituitary gland
0.000 0.541 0.458
E29.1 Testicular hypofunction
0.000 0.546 0.454
E28.2 Polycystic ovarian syndrome
0.000 0.546 0.454
E56.9 Vitamin deficiency, unspecified
0.000 0.549 0.451
E56.8 Deficiency of other vitamins
0.000 0.549 0.451
E56.0 Deficiency of vitamin E
0.000 0.549 0.451
E28.9 Ovarian dysfunction, unspecified
0.000 0.552 0.448
E28.8 Other ovarian dysfunction
0.000 0.552 0.448
E28.1 Androgen excess
0.000 0.552 0.448
E28.0 Oestrogen excess
0.000 0.552 0.448
E50.9 Vitamin A deficiency, unspecified
0.000 0.562 0.438
E50.8 Other manifestations of vitamin A deficiency
0.000 0.562 0.438
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.562 0.438
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.562 0.438
E50.5 Vitamin A deficiency with night blindness
0.000 0.562 0.438
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.562 0.438
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.562 0.438
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.562 0.438
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.562 0.438
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.562 0.438
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.562 0.438
E64.8 Sequelae of other nutritional deficiencies
0.000 0.562 0.438
E64.3 Sequelae of rickets
0.000 0.562 0.438
E64.2 Sequelae of vitamin C deficiency
0.000 0.562 0.438
E64.1 Sequelae of vitamin A deficiency
0.000 0.562 0.438
E64.0 Sequelae of protein-energy malnutrition
0.000 0.562 0.438
E07.1 Dyshormogenetic goitre
0.000 0.563 0.437
E07.0 Hypersecretion of calcitonin
0.000 0.563 0.437
E53.1 Pyridoxine deficiency
0.000 0.568 0.432
E53.0 Riboflavin deficiency
0.000 0.568 0.432
E06.4 Drug-induced thyroiditis
0.000 0.578 0.422
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.578 0.422
E06.1 Subacute thyroiditis
0.000 0.578 0.422
E06.0 Acute thyroiditis
0.000 0.578 0.422
E26.9 Hyperaldosteronism, unspecified
0.000 0.581 0.419
E26.8 Other hyperaldosteronism
0.000 0.581 0.419
E26.1 Secondary hyperaldosteronism
0.000 0.581 0.419
E07.9 Disorder of thyroid, unspecified
0.000 0.582 0.418
E34.9 Endocrine disorder, unspecified
0.000 0.583 0.417
E34.5 Androgen resistance syndrome
0.000 0.583 0.416
E34.4 Constitutional tall stature
0.000 0.583 0.416
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.583 0.416
E34.1 Other hypersecretion of intestinal hormones
0.000 0.583 0.416
E34.3 Short stature, not elsewhere classified
0.000 0.585 0.415
E23.7 Disorder of pituitary gland, unspecified
0.000 0.589 0.411
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.592 0.408
E44.1 Mild protein-energy malnutrition
0.000 0.594 0.406
E44.0 Moderate protein-energy malnutrition
0.000 0.594 0.406
E11 Non-insulin-dependent diabetes mellitus
0.000 0.602 0.398
E06.5 Other chronic thyroiditis
0.000 0.613 0.386
E63.8 Other specified nutritional deficiencies
0.000 0.616 0.384
E63.1 Imbalance of constituents of food intake
0.000 0.616 0.384
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.616 0.384
E34.0 Carcinoid syndrome
0.000 0.624 0.375
E11.9 Without complications
0.000 0.627 0.373
E28.3 Primary ovarian failure
0.000 0.644 0.356
E07.8 Other specified disorders of thyroid
0.000 0.644 0.356
E34.8 Other specified endocrine disorders
0.000 0.650 0.350
E11.6 With other specified complications
0.000 0.669 0.331
E23.6 Other disorders of pituitary gland
0.000 0.669 0.331
E63.9 Nutritional deficiency, unspecified
0.001 0.690 0.309
E26.0 Primary hyperaldosteronism
0.000 0.703 0.297
E11.7 With multiple complications
0.000 0.714 0.286
E11.8 With unspecified complications
0.000 0.724 0.276
E11.2 With renal complications
0.000 0.733 0.267
E06.3 Autoimmune thyroiditis
0.000 0.738 0.261
E11.0 With coma
0.000 0.739 0.261
E65-E68 Obesity and other hyperalimentation
0.000 0.743 0.256
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.765 0.235
E11.5 With peripheral circulatory complications
0.000 0.767 0.233
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.790 0.210
E67 Other hyperalimentation
0.000 0.816 0.184
E68 Sequelae of hyperalimentation
0.000 0.816 0.184
E21.4 Other specified disorders of parathyroid gland
0.000 0.832 0.168
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.837 0.163
E21.2 Other hyperparathyroidism
0.000 0.837 0.163
E11.1 With ketoacidosis
0.000 0.844 0.156
E11.4 With neurological complications
0.000 0.846 0.154
E04 Other non-toxic goitre
0.001 0.858 0.142
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.861 0.139
E67.8 Other specified hyperalimentation
0.000 0.868 0.132
E67.3 Hypervitaminosis D
0.000 0.868 0.132
E67.2 Megavitamin-B6 syndrome
0.000 0.868 0.132
E67.1 Hypercarotenaemia
0.000 0.868 0.132
E67.0 Hypervitaminosis A
0.000 0.868 0.132
E21.3 Hyperparathyroidism, unspecified
0.000 0.870 0.130
E04.9 Non-toxic goitre, unspecified
0.000 0.884 0.116
E04.8 Other specified non-toxic goitre
0.001 0.898 0.102
E83 Disorders of mineral metabolism
0.099 0.901 0.001
E11.3 With ophthalmic complications
0.000 0.907 0.093
K90-K93 Other diseases of the digestive system
0.000 0.917 0.083
E65 Localised adiposity
0.001 0.919 0.080
H90.2 Conductive hearing loss, unspecified
0.000 0.920 0.080
E83.9 Disorder of mineral metabolism, unspecified
0.077 0.922 0.000
H90 Conductive and sensorineural hearing loss
0.000 0.927 0.073
E83.8 Other disorders of mineral metabolism
0.071 0.929 0.001
E83.2 Disorders of zinc metabolism
0.071 0.929 0.001
E83.0 Disorders of copper metabolism
0.071 0.929 0.001
H90.3 Sensorineural hearing loss, bilateral
0.000 0.933 0.067
E83.3 Disorders of phosphorus metabolism
0.066 0.934 0.000
H90.5 Sensorineural hearing loss, unspecified
0.000 0.935 0.065
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.940 0.060
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.940 0.059
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.000 0.942 0.058
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.000 0.943 0.057
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.944 0.056
E04.0 Non-toxic diffuse goitre
0.001 0.951 0.047
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.952 0.048
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.957 0.043
K93.1 Megacolon in Chagas' disease
0.000 0.957 0.043
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.957 0.043
H90.0 Conductive hearing loss, bilateral
0.000 0.959 0.041
E53.8 Deficiency of other specified B group vitamins
0.001 0.962 0.038
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.962 0.038
E66 Obesity
0.000 0.963 0.037
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.968 0.032
E21.0 Primary hyperparathyroidism
0.000 0.969 0.030
K91.3 Postoperative intestinal obstruction
0.000 0.969 0.031
K91.1 Postgastric surgery syndromes
0.000 0.970 0.030
N30.8 Other cystitis
0.000 0.971 0.029
E66.0 Obesity due to excess calories
0.000 0.972 0.028
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.972 0.028
H26.9 Cataract, unspecified
0.000 0.973 0.027
E66.1 Drug-induced obesity
0.000 0.973 0.027
K91.5 Postcholecystectomy syndrome
0.000 0.973 0.027
M75.0 Adhesive capsulitis of shoulder
0.000 0.975 0.025
E83.4 Disorders of magnesium metabolism
0.023 0.977 0.000
E83.5 Disorders of calcium metabolism
0.023 0.977 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.978 0.022
K51 Ulcerative colitis
0.022 0.978 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.979 0.021
K51.3 Ulcerative (chronic) rectosigmoiditis
0.021 0.979 0.000
K51.2 Ulcerative (chronic) proctitis
0.021 0.979 0.000
K51.4 Pseudopolyposis of colon
0.020 0.980 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.980 0.020
K51.5 Mucosal proctocolitis
0.018 0.982 0.000
K51.9 Ulcerative colitis, unspecified
0.018 0.982 0.000
K91.4 Colostomy and enterostomy malfunction
0.000 0.983 0.017
K51.8 Other ulcerative colitis
0.016 0.984 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.016 0.984 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.016 0.984 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.015 0.985 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.985 0.014
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.987 0.013
E04.2 Non-toxic multinodular goitre
0.001 0.987 0.012
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.010 0.990 0.000
B02.2 Zoster with other nervous system involvement
0.000 0.991 0.009
H26 Other cataract
0.000 0.991 0.009
X41.9 Unspecified place
0.009 0.991 0.000
H26.1 Traumatic cataract
0.000 0.992 0.008
H26.4 After-cataract
0.000 0.992 0.008
A87.9 Viral meningitis, unspecified
0.000 0.993 0.007
K07.6 Temporomandibular joint disorders
0.007 0.993 0.000
J45.9 Asthma, unspecified
0.000 0.993 0.007
H26.2 Complicated cataract
0.000 0.993 0.007
G53.0 Postzoster neuralgia
0.000 0.993 0.007
C77.4 Inguinal and lower limb lymph nodes
0.000 0.994 0.006
E66.8 Other obesity
0.000 0.994 0.006
H26.3 Drug-induced cataract
0.000 0.994 0.006
M35 Other systemic involvement of connective tissue
0.000 0.994 0.006
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.006 0.994 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.005 0.995 0.000
V18.0 Driver injured in nontraffic accident
0.005 0.995 0.000
R06.5 Mouth breathing
0.005 0.995 0.000
M35.2 Behcet's disease
0.000 0.995 0.005
E70-E90 Metabolic disorders
0.001 0.995 0.004
A87 Viral meningitis
0.000 0.995 0.005
V18 Pedal cyclist injured in noncollision transport accident
0.005 0.995 0.000
A04.8 Other specified bacterial intestinal infections
0.000 0.995 0.005
M35.8 Other specified systemic involvement of connective tissue
0.000 0.995 0.005
F99 Mental disorder, not otherwise specified
0.005 0.995 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.000 0.995 0.004
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.004 0.996 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.996 0.004
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.996 0.004
M35.5 Multifocal fibrosclerosis
0.000 0.996 0.004
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.996 0.004
X41.0 Home
0.004 0.996 0.000
X41.8 Other specified place
0.004 0.996 0.000
X41.7 Farm
0.004 0.996 0.000
X41.6 Industrial and construction area
0.004 0.996 0.000
X41.5 Trade and service area
0.004 0.996 0.000
X41.4 Street and highway
0.004 0.996 0.000
X41.3 Sports and athletics area
0.004 0.996 0.000
X41.2 School, other institution and public administrative area
0.004 0.996 0.000
X41.1 Residential institution
0.004 0.996 0.000
D68.8 Other specified coagulation defects
0.000 0.996 0.004
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.996 0.004
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.004 0.996 0.000
V18.1 Passenger injured in nontraffic accident
0.004 0.996 0.000
V17.4 Driver injured in traffic accident
0.004 0.996 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.004 0.996 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
M35.1 Other overlap syndromes
0.000 0.996 0.004
E79 Disorders of purine and pyrimidine metabolism
0.001 0.996 0.003
U88 Agent resistant to multiple antibiotics
0.004 0.996 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
E74 Other disorders of carbohydrate metabolism
0.001 0.996 0.003
L40.9 Psoriasis, unspecified
0.004 0.996 0.000
I83 Varicose veins of lower extremities
0.004 0.996 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.004 0.996 0.000
B02 Zoster [herpes zoster]
0.000 0.996 0.004
H90-H95 Other disorders of ear
0.000 0.996 0.004
E70 Disorders of aromatic amino-acid metabolism
0.001 0.996 0.003
M35.7 Hypermobility syndrome
0.000 0.996 0.004
E77 Disorders of glycoprotein metabolism
0.001 0.996 0.003
E76 Disorders of glycosaminoglycan metabolism
0.001 0.996 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.996 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.996 0.003
V17 Pedal cyclist injured in collision with fixed or stationary object
0.004 0.996 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.004 0.996 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
V18.5 Passenger injured in traffic accident
0.004 0.996 0.000
A87.8 Other viral meningitis
0.000 0.996 0.004
A87.2 Lymphocytic choriomeningitis
0.000 0.996 0.004
A87.1 Adenoviral meningitis
0.000 0.996 0.004
A87.0 Enteroviral meningitis
0.000 0.996 0.004
I05.9 Mitral valve disease, unspecified
0.000 0.996 0.004
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.003 0.996 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.003 0.996 0.000
V18.4 Driver injured in traffic accident
0.003 0.996 0.000
E84 Cystic fibrosis
0.001 0.996 0.003
K09 Cysts of oral region, not elsewhere classified
0.000 0.996 0.004
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.996 0.003
V10-V19 Pedal cyclist injured in transport accident
0.004 0.996 0.000
E72 Other disorders of amino-acid metabolism
0.001 0.996 0.003
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.997 0.003
X40-X49 Accidental poisoning by and exposure to noxious substances
0.003 0.997 0.000
K09.2 Other cysts of jaw
0.000 0.997 0.003
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.997 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.997 0.003
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities
0.003 0.997 0.000
K92 Other diseases of digestive system
0.000 0.997 0.003
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.997 0.003
E73 Lactose intolerance
0.001 0.997 0.003
F30.9 Manic episode, unspecified
0.003 0.997 0.000
H26.0 Infantile, juvenile and presenile cataract
0.001 0.997 0.002
F30.2 Mania with psychotic symptoms
0.003 0.997 0.000
K09.1 Developmental (nonodontogenic) cysts of oral region
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.997 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.997 0.003
E79.1 Lesch-Nyhan syndrome
0.001 0.997 0.003
W22.9 Unspecified place
0.003 0.997 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.003 0.997 0.000
E70.3 Albinism
0.001 0.997 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.997 0.003
E74.2 Disorders of galactose metabolism
0.001 0.997 0.003
E74.1 Disorders of fructose metabolism
0.001 0.997 0.003
E85 Amyloidosis
0.001 0.997 0.002
B02.7 Disseminated zoster
0.000 0.997 0.003
B02.1 Zoster meningitis
0.000 0.997 0.003
B02.0 Zoster encephalitis
0.000 0.997 0.003
T91.3 Sequelae of injury of spinal cord
0.003 0.997 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.003 0.997 0.000
V18.3 Person injured while boarding or alighting
0.003 0.997 0.000
W25.9 Unspecified place
0.003 0.997 0.000
B02.8 Zoster with other complications
0.000 0.997 0.003
V17.2 Unspecified pedal cyclist injured in nontraffic accident
0.003 0.997 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.997 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.997 0.002
E70.2 Disorders of tyrosine metabolism
0.001 0.997 0.002
E70.1 Other hyperphenylalaninaemias
0.001 0.997 0.002
E70.0 Classical phenylketonuria
0.001 0.997 0.002
E74.0 Glycogen storage disease
0.001 0.997 0.002
K09.0 Developmental odontogenic cysts
0.000 0.997 0.003
Y84.8 Other medical procedures
0.003 0.997 0.000
F30 Manic episode
0.003 0.997 0.000
K09.9 Cyst of oral region, unspecified
0.000 0.997 0.003
V10 Pedal cyclist injured in collision with pedestrian or animal
0.003 0.997 0.000
E71.3 Disorders of fatty-acid metabolism
0.001 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.997 0.002
E71.0 Maple-syrup-urine disease
0.001 0.997 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.997 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.997 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.997 0.002
E76.2 Other mucopolysaccharidoses
0.001 0.997 0.002
E76.1 Mucopolysaccharidosis, type II
0.001 0.997 0.002
E76.0 Mucopolysaccharidosis, type I
0.001 0.997 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.997 0.002
E77.8 Other disorders of glycoprotein metabolism
0.001 0.997 0.002
E77.1 Defects in glycoprotein degradation
0.001 0.997 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.997 0.002
V17.9 Unspecified pedal cyclist injured in traffic accident
0.003 0.997 0.000
V17.5 Passenger injured in traffic accident
0.003 0.997 0.000
V17.3 Person injured while boarding or alighting
0.003 0.997 0.000
V17.1 Passenger injured in nontraffic accident
0.003 0.997 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.003 0.997 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.003 0.997 0.000
M21.1 Varus deformity, not elsewhere classified
0.003 0.997 0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.003 0.997 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.003 0.997 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.003 0.997 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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