TreeWAS – Variant ID: rs1437898

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D63.0 Anaemia in neoplastic disease	0.048	0.952	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.023	0.977	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.981	0.019
C34.9 Bronchus or lung, unspecified	0.016	0.984	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.013	0.987	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.009	0.990	0.000
C34 Malignant neoplasm of bronchus and lung	0.009	0.991	0.000
C34.1 Upper lobe, bronchus or lung	0.009	0.991	0.000
S52.10 Fracture of upper end of radius (closed)	0.008	0.992	0.000
C34.0 Main bronchus	0.007	0.992	0.000
C34.8 Overlapping lesion of bronchus and lung	0.007	0.993	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.993	0.007
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.006	0.994	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.006	0.994	0.000
N30.3 Trigonitis	0.006	0.994	0.000
S82.81 Fractures of other parts of lower leg (open)	0.005	0.995	0.000
C34.2 Middle lobe, bronchus or lung	0.005	0.995	0.000
N30.1 Interstitial cystitis (chronic)	0.005	0.995	0.000
S82.8 Fractures of other parts of lower leg	0.005	0.995	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.005	0.995	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.005	0.995	0.000
E13.9 Without complications	0.005	0.995	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.995	0.005
N30 Cystitis	0.004	0.996	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.004	0.996	0.000
N30.8 Other cystitis	0.004	0.996	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.004	0.996	0.000
R44.0 Auditory hallucinations	0.000	0.996	0.004
C33 Malignant neoplasm of trachea	0.004	0.996	0.000
C37 Malignant neoplasm of thymus	0.004	0.996	0.000
S82.86 Maisonneuve's fracture	0.004	0.996	0.000
C38.4 Pleura	0.004	0.996	0.000
S52.1 Fracture of upper end of radius	0.004	0.996	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.004	0.996	0.000
D32.0 Cerebral meninges	0.000	0.996	0.004
R44.3 Hallucinations, unspecified	0.000	0.996	0.004
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.004	0.996	0.000
N30.2 Other chronic cystitis	0.004	0.996	0.000
N30.0 Acute cystitis	0.004	0.996	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.996	0.004
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.996	0.004
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.996	0.003
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.996	0.003
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.996	0.003
Z11.5 Special screening examination for other viral diseases	0.000	0.996	0.003
C30.0 Nasal cavity	0.003	0.996	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.996	0.004
C38.3 Mediastinum, part unspecified	0.003	0.996	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.997	0.003
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.003	0.997	0.000
C38.2 Posterior mediastinum	0.003	0.997	0.000
C38.1 Anterior mediastinum	0.003	0.997	0.000
C38.0 Heart	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
C31 Malignant neoplasm of accessory sinuses	0.003	0.997	0.000
C34.3 Lower lobe, bronchus or lung	0.003	0.997	0.000
C30.1 Middle ear	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.997	0.003
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.997	0.003
R44.2 Other hallucinations	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
S52.11 Fracture of upper end of radius (open)	0.003	0.997	0.000
R44.1 Visual hallucinations	0.000	0.997	0.003
C39.9 Ill-defined sites within the respiratory system	0.003	0.997	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.003	0.997	0.000
C39.0 Upper respiratory tract, part unspecified	0.003	0.997	0.000
N71.1 Chronic inflammatory disease of uterus	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
F43.1 Posttraumatic stress disorder	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.003
N30.4 Irradiation cystitis	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
C32.2 Subglottis	0.003	0.997	0.000
Z03.1 Observation for suspected malignant neoplasm	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
C31.9 Accessory sinus, unspecified	0.002	0.997	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.997	0.000
C31.3 Sphenoidal sinus	0.002	0.997	0.000
C31.2 Frontal sinus	0.002	0.997	0.000
C31.1 Ethmoidal sinus	0.002	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.997	0.003
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.002	0.997	0.000
C32.3 Laryngeal cartilage	0.002	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
K81.0 Acute cholecystitis	0.000	0.997	0.003
E26 Hyperaldosteronism	0.000	0.997	0.002
K76.8 Other specified diseases of liver	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
M47.2 Other spondylosis with radiculopathy	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
C31.0 Maxillary sinus	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.998	0.002
H46 Optic neuritis	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.002	0.998	0.000
D16.4 Bones of skull and face	0.002	0.998	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.000	0.998	0.002
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
K59.4 Anal spasm	0.000	0.998	0.002
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
O47.9 False labour, unspecified	0.002	0.998	0.000
D16.0 Scapula and long bones of upper limb	0.002	0.998	0.000
F20.8 Other schizophrenia	0.000	0.998	0.002
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.002	0.998	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.002	0.998	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.002	0.998	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.002	0.998	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.002	0.998	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.002	0.998	0.000
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
K06 Other disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.998	0.002
Y40.0 Penicillins	0.000	0.998	0.002
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.998	0.002
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.998	0.002
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.998	0.002
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.998	0.002
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
M79.70 Fibromyalgia (Multiple sites)	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D16.2 Long bones of lower limb	0.002	0.998	0.000
D16 Benign neoplasm of bone and articular cartilage	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
C22.9 Liver, unspecified	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
K82.1 Hydrops of gallbladder	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
C32.1 Supraglottis	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
D16.1 Short bones of upper limb	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
H47.2 Optic atrophy	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
K06.1 Gingival enlargement	0.000	0.998	0.002
N90.7 Vulvar cyst	0.000	0.998	0.002
E20-E35 Disorders of other endocrine glands	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
D14.1 Larynx	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.000	0.998	0.002
M86.8 Other osteomyelitis	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.002	0.998	0.000
E25 Adrenogenital disorders	0.000	0.998	0.002
D16.3 Short bones of lower limb	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
D16.7 Ribs, sternum and clavicle	0.002	0.998	0.000
D16.6 Vertebral column	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.001
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.998	0.002
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
D16.9 Bone and articular cartilage, unspecified	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.998	0.001
C43.5 Malignant melanoma of trunk	0.002	0.998	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.000	0.998	0.001
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
N34.3 Urethral syndrome, unspecified	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
S81.0 Open wound of knee	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.001
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.001
Z89 Acquired absence of limb	0.000	0.998	0.002
A04.7 Enterocolitis due to Clostridium difficile	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.000	0.998	0.002
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.998	0.000
M71.34 Other bursal cyst (Hand)	0.000	0.998	0.001
M86.89 Other osteomyelitis (Site unspecified)	0.000	0.998	0.001
M86.88 Other osteomyelitis (Other)	0.000	0.998	0.001
M86.84 Other osteomyelitis (Hand)	0.000	0.998	0.001
M86.83 Other osteomyelitis (Forearm)	0.000	0.998	0.001
M86.82 Other osteomyelitis (Upper arm)	0.000	0.998	0.001
M86.81 Other osteomyelitis (Shoulder region)	0.000	0.998	0.001
M86.80 Other osteomyelitis (Multiple sites)	0.000	0.998	0.001
D23.9 Skin, unspecified	0.002	0.998	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
N88.2 Stricture and stenosis of cervix uteri	0.002	0.998	0.000
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
D83 Common variable immunodeficiency	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.001
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.001
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.001
C22.0 Liver cell carcinoma	0.000	0.998	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.001
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.001
E25.8 Other adrenogenital disorders	0.000	0.998	0.001
E32 Diseases of thymus	0.000	0.998	0.001
E28 Ovarian dysfunction	0.000	0.998	0.001
M86.86 Other osteomyelitis (Lower leg)	0.000	0.999	0.001
K06.0 Gingival recession	0.000	0.999	0.001
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.999	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
E24 Cushing's syndrome	0.000	0.999	0.001
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
H16.9 Keratitis, unspecified	0.001	0.999	0.000
J38.3 Other diseases of vocal cords	0.001	0.999	0.000
L93.0 Discoid lupus erythematosus	0.000	0.999	0.001
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.000	0.999	0.001
D61 Other aplastic anaemias	0.001	0.999	0.000
D16.5 Lower jaw bone	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.000	0.999	0.001
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.999	0.001
Z89.2 Acquired absence of upper limb above wrist	0.000	0.999	0.001
E31 Polyglandular dysfunction	0.000	0.999	0.001
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.999	0.001
D61.0 Constitutional aplastic anaemia	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
E40-E46 Malnutrition	0.001	0.999	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999	0.000
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.000	0.999	0.001
M86 Osteomyelitis	0.000	0.999	0.001
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M86.68 Other chronic osteomyelitis (Other)	0.000	0.999	0.001
M86.66 Other chronic osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.64 Other chronic osteomyelitis (Hand)	0.000	0.999	0.001
M86.63 Other chronic osteomyelitis (Forearm)	0.000	0.999	0.001
M86.62 Other chronic osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.61 Other chronic osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.60 Other chronic osteomyelitis (Multiple sites)	0.000	0.999	0.001
S02.51 Fracture of tooth (open)	0.000	0.999	0.001
D60.8 Other acquired pure red cell aplasias	0.001	0.999	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.999	0.000
D60.0 Chronic acquired pure red cell aplasia	0.001	0.999	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.999	0.001
E30.8 Other disorders of puberty	0.000	0.999	0.001
E30.1 Precocious puberty	0.000	0.999	0.001
E30.0 Delayed puberty	0.000	0.999	0.001
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.999	0.001
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.999	0.001
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.999	0.001
S82.7 Multiple fractures of lower leg	0.001	0.999	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.999	0.001
Z89.1 Acquired absence of hand and wrist	0.000	0.999	0.001
E16 Other disorders of pancreatic internal secretion	0.001	0.999	0.000
M85.64 Other cyst of bone (Hand)	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.001	0.999	0.000
M86.1 Other acute osteomyelitis	0.000	0.999	0.001
N93.0 Postcoital and contact bleeding	0.000	0.999	0.001
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.999	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.999	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.999	0.000
Q55.3 Atresia of vas deferens	0.001	0.999	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.999	0.000
Z71.9 Counselling, unspecified	0.001	0.999	0.000
M54.37 Sciatica (Lumbosacral region)	0.001	0.999	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
Y40.6 Rifamycins	0.000	0.999	0.001
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.999	0.001
M86.17 Other acute osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
E28.9 Ovarian dysfunction, unspecified	0.000	0.999	0.001
E28.8 Other ovarian dysfunction	0.000	0.999	0.001
E28.1 Androgen excess	0.000	0.999	0.001
E28.0 Oestrogen excess	0.000	0.999	0.001
E32.8 Other diseases of thymus	0.000	0.999	0.001
E32.1 Abscess of thymus	0.000	0.999	0.001
E32.0 Persistent hyperplasia of thymus	0.000	0.999	0.001
Y40 Systemic antibiotics	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.999	0.001
E24.3 Ectopic ACTH syndrome	0.000	0.999	0.001
E24.2 Drug-induced Cushing's syndrome	0.000	0.999	0.001
E24.1 Nelson's syndrome	0.000	0.999	0.001
M86.69 Other chronic osteomyelitis (Site unspecified)	0.000	0.999	0.001
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.000	0.999	0.001
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.000	0.999	0.001
D61.8 Other specified aplastic anaemias	0.001	0.999	0.000
D61.3 Idiopathic aplastic anaemia	0.001	0.999	0.000
D61.2 Aplastic anaemia due to other external agents	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.999	0.000
O47 False labour	0.001	0.999	0.000
E24.8 Other Cushing's syndrome	0.000	0.999	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.999	0.001
E31.8 Other polyglandular dysfunction	0.000	0.999	0.001
E31.1 Polyglandular hyperfunction	0.000	0.999	0.001
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.000	0.999	0.001
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.000	0.999	0.001
H48.0 Optic atrophy in diseases classified elsewhere	0.000	0.999	0.001
M86.4 Chronic osteomyelitis with draining sinus	0.000	0.999	0.001
Y40.4 Tetracyclines	0.000	0.999	0.001
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.999	0.001
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.999	0.001
E32.9 Disease of thymus, unspecified	0.000	0.999	0.001
M86.5 Other chronic haematogenous osteomyelitis	0.000	0.999	0.001
M86.3 Chronic multifocal osteomyelitis	0.000	0.999	0.001
M86.2 Subacute osteomyelitis	0.000	0.999	0.001
M86.0 Acute haematogenous osteomyelitis	0.000	0.999	0.001
N71.9 Inflammatory disease of uterus, unspecified	0.001	0.999	0.000
E20 Hypoparathyroidism	0.000	0.999	0.001
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.999	0.000
E45 Retarded development following protein-energy malnutrition	0.001	0.999	0.000
E43 Unspecified severe protein-energy malnutrition	0.001	0.999	0.000
E42 Marasmic kwashiorkor	0.001	0.999	0.000
E41 Nutritional marasmus	0.001	0.999	0.000
E40 Kwashiorkor	0.001	0.999	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.000	0.999	0.001
S82.71 Multiple fractures of lower leg (open)	0.001	0.999	0.000
E10.2 With renal complications	0.001	0.999	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.999	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.999	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.999	0.000
E16.3 Increased secretion of glucagon	0.001	0.999	0.000
Q61.3 Polycystic kidney, unspecified	0.001	0.999	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
S82 Fracture of lower leg, including ankle	0.001	0.999	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.18 Other acute osteomyelitis (Other)	0.000	0.999	0.001
M86.16 Other acute osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.14 Other acute osteomyelitis (Hand)	0.000	0.999	0.001
M86.13 Other acute osteomyelitis (Forearm)	0.000	0.999	0.001
M86.12 Other acute osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.11 Other acute osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.10 Other acute osteomyelitis (Multiple sites)	0.000	0.999	0.001
E24.9 Cushing's syndrome, unspecified	0.000	0.999	0.001
S81.8 Open wound of other parts of lower leg	0.001	0.999	0.000
W49.9 Unspecified place	0.000	0.999	0.001
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.000	0.999	0.001
Y42.2 Antithyroid drugs	0.001	0.999	0.000
M79.79 Fibromyalgia (Site unspecified)	0.001	0.999	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.999	0.001
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
B44.9 Aspergillosis, unspecified	0.001	0.999	0.000
D61.1 Drug-induced aplastic anaemia	0.001	0.999	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.999	0.001
Q61.0 Congenital single renal cyst	0.001	0.999	0.000
H16 Keratitis	0.001	0.999	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.000	0.999	0.001
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.000	0.999	0.001
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.000	0.999	0.001
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.000	0.999	0.001
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.000	0.999	0.001
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.000	0.999	0.001
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.000	0.999	0.001
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.000	0.999	0.001
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.999	0.001
S22.50 Flail chest (closed)	0.000	0.999	0.001
C22.7 Other specified carcinomas of liver	0.000	0.999	0.001
C22.4 Other sarcomas of liver	0.000	0.999	0.001
C22.3 Angiosarcoma of liver	0.000	0.999	0.001
C22.2 Hepatoblastoma	0.000	0.999	0.001
G97.8 Other postprocedural disorders of nervous system	0.000	0.999	0.001
Z89.4 Acquired absence of foot and ankle	0.000	0.999	0.001
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.08 Acute haematogenous osteomyelitis (Other)	0.000	0.999	0.001
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.04 Acute haematogenous osteomyelitis (Hand)	0.000	0.999	0.001
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.000	0.999	0.001
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.000	0.999	0.001
M86.29 Subacute osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.28 Subacute osteomyelitis (Other)	0.000	0.999	0.001
M86.27 Subacute osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.26 Subacute osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.24 Subacute osteomyelitis (Hand)	0.000	0.999	0.001
M86.23 Subacute osteomyelitis (Forearm)	0.000	0.999	0.001
M86.22 Subacute osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.21 Subacute osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.20 Subacute osteomyelitis (Multiple sites)	0.000	0.999	0.001
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.38 Chronic multifocal osteomyelitis (Other)	0.000	0.999	0.001
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.34 Chronic multifocal osteomyelitis (Hand)	0.000	0.999	0.001
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations