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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs143813799
log Bayes Factor = 18.0084
Chromosome 17   position 60,023,795  (GRCh37) Explore rs143813799 on Ensembl!
Variant rs143813799 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Z92 Personal history of medical treatment
0.995 0.005 0.000
J90-J94 Other diseases of pleura
0.994 0.006 0.000
M25 Other joint disorders, not elsewhere classified
0.993 0.007 0.000
M25.5 Pain in joint
0.993 0.007 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.991 0.009 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.989 0.011 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.988 0.012 0.000
Chapter II Neoplasms
0.987 0.013 0.000
J90 Pleural effusion, not elsewhere classified
0.986 0.014 0.000
Z37 Outcome of delivery
0.985 0.015 0.000
K14 Diseases of tongue
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.981 0.019 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.978 0.022 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.974 0.026 0.000
I30-I52 Other forms of heart disease
0.974 0.026 0.000
C15-C26 Malignant neoplasms of digestive organs
0.973 0.027 0.000
K14.0 Glossitis
0.967 0.033 0.000
Z36 Antenatal screening
0.963 0.037 0.000
Z37.0 Single live birth
0.960 0.040 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.956 0.044 0.000
K70-K77 Diseases of liver
0.955 0.045 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.952 0.048 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.950 0.050 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.949 0.051 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.948 0.052 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.947 0.053 0.000
F30-F39 Mood [affective] disorders
0.941 0.059 0.000
K90-K93 Other diseases of the digestive system
0.940 0.060 0.000
I34 Nonrheumatic mitral valve disorders
0.940 0.060 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.936 0.064 0.000
M50-M54 Other dorsopathies
0.930 0.070 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.927 0.073 0.000
K92 Other diseases of digestive system
0.924 0.076 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.923 0.077 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.920 0.080 0.000
M21 Other acquired deformities of limbs
0.920 0.080 0.000
Z36.9 Antenatal screening, unspecified
0.919 0.081 0.000
K92.1 Melaena
0.919 0.081 0.000
R10 Abdominal and pelvic pain
0.917 0.083 0.000
R11 Nausea and vomiting
0.914 0.086 0.000
K01 Embedded and impacted teeth
0.911 0.089 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.911 0.089 0.000
R10.4 Other and unspecified abdominal pain
0.907 0.093 0.000
K11 Diseases of salivary glands
0.907 0.093 0.000
Z35 Supervision of high-risk pregnancy
0.906 0.094 0.000
F10.2 Dependence syndrome
0.906 0.094 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.903 0.097 0.000
I05-I09 Chronic rheumatic heart diseases
0.901 0.099 0.000
J93 Pneumothorax
0.899 0.101 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.897 0.103 0.000
R15 Faecal incontinence
0.897 0.103 0.000
F32 Depressive episode
0.891 0.109 0.000
Z34 Supervision of normal pregnancy
0.886 0.114 0.000
K83 Other diseases of biliary tract
0.881 0.119 0.000
M25.4 Effusion of joint
0.881 0.119 0.000
K08 Other disorders of teeth and supporting structures
0.881 0.119 0.000
M54 Dorsalgia
0.880 0.120 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.877 0.123 0.000
F20 Schizophrenia
0.877 0.123 0.000
K70 Alcoholic liver disease
0.870 0.130 0.000
I34.0 Mitral (valve) insufficiency
0.870 0.130 0.000
Z33 Pregnant state, incidental
0.867 0.132 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.867 0.133 0.000
Z37.2 Twins, both liveborn
0.867 0.133 0.000
Chapter XX External causes of morbidity and mortality
0.866 0.134 0.000
M25.57 Pain in joint (Ankle and foot)
0.866 0.134 0.000
D60-D64 Aplastic and other anaemias
0.866 0.134 0.000
Z88.2 Personal history of allergy to sulphonamides
0.865 0.135 0.000
I42 Cardiomyopathy
0.865 0.135 0.000
D80-D89 Certain disorders involving the immune mechanism
0.864 0.136 0.000
F32.9 Depressive episode, unspecified
0.862 0.138 0.000
I49 Other cardiac arrhythmias
0.861 0.139 0.000
J95-J99 Other diseases of the respiratory system
0.860 0.140 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.860 0.140 0.000
J09-J18 Influenza and pneumonia
0.860 0.140 0.000
Chapter VII Diseases of the eye and adnexa
0.859 0.141 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.854 0.146 0.000
Z87 Personal history of other diseases and conditions
0.853 0.147 0.000
C77.5 Intrapelvic lymph nodes
0.850 0.150 0.000
I44 Atrioventricular and left bundle-branch block
0.850 0.150 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.849 0.151 0.000
K01.1 Impacted teeth
0.848 0.152 0.000
I34.1 Mitral (valve) prolapse
0.847 0.153 0.000
R17 Unspecified jaundice
0.846 0.154 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.846 0.154 0.000
C20 Malignant neoplasm of rectum
0.844 0.156 0.000
O60-O75 Complications of labour and delivery
0.843 0.157 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.840 0.160 0.000
Z88.5 Personal history of allergy to narcotic agent
0.840 0.160 0.000
K65-K67 Diseases of peritoneum
0.839 0.161 0.000
K83.1 Obstruction of bile duct
0.839 0.161 0.000
Z93 Artificial opening status
0.837 0.163 0.000
R50-R69 General symptoms and signs
0.836 0.164 0.000
Z35.5 Supervision of elderly primigravida
0.836 0.164 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.835 0.165 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.832 0.168 0.000
C15 Malignant neoplasm of oesophagus
0.831 0.169 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.829 0.171 0.000
I05 Rheumatic mitral valve diseases
0.829 0.171 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.828 0.172 0.000
F41 Other anxiety disorders
0.828 0.172 0.000
J93.9 Pneumothorax, unspecified
0.827 0.173 0.000
C77.9 Lymph node, unspecified
0.827 0.173 0.000
Z88.6 Personal history of allergy to analgesic agent
0.827 0.173 0.000
R18 Ascites
0.824 0.176 0.000
M54.5 Low back pain
0.822 0.178 0.000
Chapter I Certain infectious and parasitic diseases
0.822 0.178 0.000
K12 Stomatitis and related lesions
0.819 0.181 0.000
L60-L75 Disorders of skin appendages
0.819 0.181 0.000
M25.56 Pain in joint (Lower leg)
0.819 0.181 0.000
Z36.8 Other antenatal screening
0.817 0.183 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.816 0.184 0.000
K86 Other diseases of pancreas
0.812 0.188 0.000
K74 Fibrosis and cirrhosis of liver
0.811 0.189 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.811 0.189 0.000
M25.59 Pain in joint (Site unspecified)
0.811 0.189 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.811 0.189 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.810 0.190 0.000
K70.9 Alcoholic liver disease, unspecified
0.809 0.191 0.000
Z39 Postpartum care and examination
0.808 0.191 0.000
M21.3 Wrist or foot drop (acquired)
0.808 0.192 0.000
I50 Heart failure
0.807 0.193 0.000
K82 Other diseases of gallbladder
0.806 0.194 0.000
J94 Other pleural conditions
0.806 0.194 0.000
H30-H36 Disorders of choroid and retina
0.800 0.200 0.000
F60-F69 Disorders of adult personality and behaviour
0.799 0.201 0.000
D64 Other anaemias
0.799 0.201 0.000
C34 Malignant neoplasm of bronchus and lung
0.798 0.202 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.797 0.203 0.000
M25.46 Effusion of joint (Lower leg)
0.797 0.203 0.000
R60 Oedema, not elsewhere classified
0.797 0.203 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.795 0.205 0.000
O42 Premature rupture of membranes
0.793 0.207 0.000
I27 Other pulmonary heart diseases
0.793 0.207 0.000
K07 Dentofacial anomalies [including malocclusion]
0.792 0.207 0.000
C78.7 Secondary malignant neoplasm of liver
0.792 0.208 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.792 0.208 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.789 0.211 0.000
K14.9 Disease of tongue, unspecified
0.788 0.211 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.786 0.214 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.783 0.217 0.000
Z92.3 Personal history of irradiation
0.783 0.217 0.000
O36 Maternal care for other known or suspected foetal problems
0.783 0.217 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.783 0.217 0.000
Z91.5 Personal history of self-harm
0.783 0.217 0.000
M25.53 Pain in joint (Forearm)
0.782 0.218 0.000
L60 Nail disorders
0.780 0.220 0.000
F20.9 Schizophrenia, unspecified
0.777 0.223 0.000
H35 Other retinal disorders
0.776 0.224 0.000
R52 Pain, not elsewhere classified
0.775 0.225 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.775 0.225 0.000
D86 Sarcoidosis
0.773 0.227 0.000
F41.9 Anxiety disorder, unspecified
0.771 0.229 0.000
M54.59 Low back pain (Site unspecified)
0.771 0.229 0.000
K10 Other diseases of jaws
0.769 0.231 0.000
K13 Other diseases of lip and oral mucosa
0.769 0.231 0.000
K66 Other disorders of peritoneum
0.763 0.237 0.000
Z89 Acquired absence of limb
0.763 0.237 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.763 0.237 0.000
C21 Malignant neoplasm of anus and anal canal
0.763 0.237 0.000
C77.8 Lymph nodes of multiple regions
0.763 0.237 0.000
M25.50 Pain in joint (Multiple sites)
0.762 0.237 0.000
Z31 Procreative management
0.762 0.238 0.000
C51-C58 Malignant neoplasms of female genital organs
0.761 0.239 0.000
I51 Complications and ill-defined descriptions of heart disease
0.761 0.239 0.000
J30-J39 Other diseases of upper respiratory tract
0.761 0.239 0.000
H35.3 Degeneration of macula and posterior pole
0.760 0.240 0.000
O30 Multiple gestation
0.759 0.241 0.000
I42.0 Dilated cardiomyopathy
0.758 0.242 0.000
R14 Flatulence and related conditions
0.757 0.243 0.000
C25 Malignant neoplasm of pancreas
0.757 0.243 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.757 0.243 0.000
I50.0 Congestive heart failure
0.756 0.244 0.000
M21.0 Valgus deformity, not elsewhere classified
0.755 0.245 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.753 0.247 0.000
M31 Other necrotising vasculopathies
0.752 0.247 0.000
L40-L45 Papulosquamous disorders
0.752 0.248 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.752 0.248 0.000
F20.0 Paranoid schizophrenia
0.751 0.249 0.000
D64.9 Anaemia, unspecified
0.751 0.249 0.000
C78.0 Secondary malignant neoplasm of lung
0.750 0.250 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.750 0.250 0.000
K11.6 Mucocele of salivary gland
0.750 0.250 0.000
O47 False labour
0.749 0.251 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.749 0.251 0.000
K08.3 Retained dental root
0.749 0.251 0.000
I44.7 Left bundle-branch block, unspecified
0.749 0.251 0.000
C77.3 Axillary and upper limb lymph nodes
0.749 0.251 0.000
C50-C50 Malignant neoplasm of breast
0.749 0.251 0.000
Z86 Personal history of certain other diseases
0.748 0.252 0.000
Z88.0 Personal history of allergy to penicillin
0.748 0.252 0.000
M25.8 Other specified joint disorders
0.747 0.253 0.000
Q21 Congenital malformations of cardiac septa
0.747 0.253 0.000
K14.8 Other diseases of tongue
0.745 0.255 0.000
R25 Abnormal involuntary movements
0.745 0.255 0.000
K09 Cysts of oral region, not elsewhere classified
0.743 0.257 0.000
Chapter VI Diseases of the nervous system
0.743 0.257 0.000
F23 Acute and transient psychotic disorders
0.743 0.257 0.000
K11.2 Sialoadenitis
0.742 0.258 0.000
J98 Other respiratory disorders
0.741 0.259 0.000
A30-A49 Other bacterial diseases
0.739 0.260 0.000
C22.9 Liver, unspecified
0.739 0.261 0.000
J60-J70 Lung diseases due to external agents
0.738 0.262 0.000
K11.5 Sialolithiasis
0.737 0.263 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.737 0.263 0.000
I36 Nonrheumatic tricuspid valve disorders
0.736 0.264 0.000
M24 Other specific joint derangements
0.735 0.265 0.000
Z97 Presence of other devices
0.734 0.266 0.000
J91 Pleural effusion in conditions classified elsewhere
0.734 0.266 0.000
M54.1 Radiculopathy
0.733 0.267 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.732 0.268 0.000
J20-J22 Other acute lower respiratory infections
0.732 0.268 0.000
C15.9 Oesophagus, unspecified
0.731 0.269 0.000
J18 Pneumonia, organism unspecified
0.731 0.269 0.000
I49.1 Atrial premature depolarisation
0.730 0.270 0.000
F25 Schizoaffective disorders
0.729 0.270 0.000
Z91.6 Personal history of other physical trauma
0.729 0.271 0.000
F29 Unspecified nonorganic psychosis
0.729 0.271 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.728 0.272 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.728 0.272 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.728 0.272 0.000
F10.1 Harmful use
0.728 0.272 0.000
F45 Somatoform disorders
0.727 0.273 0.000
L20-L30 Dermatitis and eczema
0.726 0.274 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.726 0.274 0.000
J00-J06 Acute upper respiratory infections
0.725 0.274 0.000
M40-M43 Deforming dorsopathies
0.724 0.276 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.723 0.276 0.000
Z93.2 Ileostomy status
0.724 0.276 0.000
F43 Reaction to severe stress, and adjustment disorders
0.723 0.277 0.000
R60.9 Oedema, unspecified
0.722 0.278 0.000
M25.54 Pain in joint (Hand)
0.720 0.280 0.000
F33 Recurrent depressive disorder
0.720 0.280 0.000
M86-M90 Other osteopathies
0.720 0.280 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.719 0.281 0.000
C77.2 Intra-abdominal lymph nodes
0.718 0.282 0.000
I44.3 Other and unspecified atrioventricular block
0.718 0.282 0.000
F99-F99 Unspecified mental disorder
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z38 Liveborn infants according to place of birth
0.717 0.283 0.000
Z32 Pregnancy examination and test
0.717 0.283 0.000
M22 Disorders of patella
0.717 0.283 0.000
K03 Other diseases of hard tissues of teeth
0.717 0.283 0.000
K00 Disorders of tooth development and eruption
0.717 0.283 0.000
H55-H59 Other disorders of eye and adnexa
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
L60.0 Ingrowing nail
0.716 0.284 0.000
Z34.0 Supervision of normal first pregnancy
0.716 0.284 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.716 0.284 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.715 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.284 0.000
Q50-Q56 Congenital malformations of genital organs
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.714 0.286 0.000
C77.4 Inguinal and lower limb lymph nodes
0.714 0.286 0.000
K05 Gingivitis and periodontal diseases
0.714 0.286 0.000
K75 Other inflammatory liver diseases
0.714 0.286 0.000
M91-M94 Chondropathies
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
Z92.9 Personal history of medical treatment, unspecified
0.713 0.287 0.000
Z92.8 Personal history of other medical treatment
0.713 0.287 0.000
Z92.5 Personal history of rehabilitation measures
0.713 0.287 0.000
Z92.0 Personal history of contraception
0.713 0.287 0.000
M25.9 Joint disorder, unspecified
0.712 0.288 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.712 0.288 0.000
M25.3 Other instability of joint
0.712 0.288 0.000
M25.2 Flail joint
0.712 0.288 0.000
M25.1 Fistula of joint
0.712 0.288 0.000
M25.0 Haemarthrosis
0.712 0.288 0.000
M25.58 Pain in joint (Other)
0.712 0.288 0.000
M25.52 Pain in joint (Upper arm)
0.712 0.288 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
M25.51 Pain in joint (Shoulder region)
0.712 0.288 0.000
K76 Other diseases of liver
0.711 0.289 0.000
R60.0 Localised oedema
0.711 0.289 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.710 0.290 0.000
C77.0 Lymph nodes of head, face and neck
0.710 0.290 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.710 0.290 0.000
K72 Hepatic failure, not elsewhere classified
0.709 0.290 0.000
I27.0 Primary pulmonary hypertension
0.709 0.291 0.000
I49.9 Cardiac arrhythmia, unspecified
0.709 0.291 0.000
M80-M85 Disorders of bone density and structure
0.709 0.291 0.000
K35-K38 Diseases of appendix
0.708 0.292 0.000
M21.6 Other acquired deformities of ankle and foot
0.708 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.708 0.292 0.000
K82.8 Other specified diseases of gallbladder
0.708 0.292 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.708 0.292 0.000
K85 Acute pancreatitis
0.707 0.293 0.000
D80 Immunodeficiency with predominantly antibody defects
0.707 0.293 0.000
M53 Other dorsopathies, not elsewhere classified
0.706 0.293 0.000
Z37.9 Outcome of delivery unspecified
0.706 0.294 0.000
Z37.7 Other multiple births, all stillborn
0.706 0.294 0.000
Z37.6 Other multiple births, some liveborn
0.706 0.294 0.000
Z37.5 Other multiple births, all liveborn
0.706 0.294 0.000
Z37.4 Twins, both stillborn
0.706 0.294 0.000
Z37.3 Twins, one liveborn and one stillborn
0.706 0.294 0.000
Z37.1 Single stillbirth
0.706 0.294 0.000
K14.6 Glossodynia
0.706 0.294 0.000
K14.5 Plicated tongue
0.706 0.294 0.000
K14.4 Atrophy of tongue papillae
0.706 0.294 0.000
K14.3 Hypertrophy of tongue papillae
0.706 0.294 0.000
K14.2 Median rhomboid glossitis
0.706 0.294 0.000
K14.1 Geographic tongue
0.706 0.294 0.000
R94 Abnormal results of function studies
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
M65-M68 Disorders of synovium and tendon
0.703 0.297 0.000
L03 Cellulitis
0.703 0.297 0.000
K81 Cholecystitis
0.702 0.298 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.702 0.298 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.298 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.701 0.298 0.000
K74.6 Other and unspecified cirrhosis of liver
0.701 0.299 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.700 0.300 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
M54.4 Lumbago with sciatica
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.698 0.302 0.000
I48 Atrial fibrillation and flutter
0.698 0.302 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.698 0.302 0.000
I41 Myocarditis in diseases classified elsewhere
0.698 0.302 0.000
I40 Acute myocarditis
0.698 0.302 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.698 0.302 0.000
I37 Pulmonary valve disorders
0.698 0.302 0.000
I33 Acute and subacute endocarditis
0.698 0.302 0.000
I32 Pericarditis in diseases classified elsewhere
0.698 0.302 0.000
I30 Acute pericarditis
0.698 0.302 0.000
C17 Malignant neoplasm of small intestine
0.698 0.302 0.000
C23 Malignant neoplasm of gallbladder
0.698 0.302 0.000
C34.3 Lower lobe, bronchus or lung
0.697 0.303 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.697 0.303 0.000
K66.0 Peritoneal adhesions
0.697 0.303 0.000
I05.0 Mitral stenosis
0.697 0.303 0.000
C80 Malignant neoplasm without specification of site
0.696 0.304 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.695 0.304 0.000
O48 Prolonged pregnancy
0.695 0.304 0.000
O63 Long labour
0.695 0.305 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.695 0.305 0.000
C24.1 Ampulla of Vater
0.694 0.306 0.000
C22.0 Liver cell carcinoma
0.694 0.306 0.000
I38 Endocarditis, valve unspecified
0.693 0.307 0.000
I05.9 Mitral valve disease, unspecified
0.693 0.307 0.000
L91 Hypertrophic disorders of skin
0.692 0.308 0.000
I08 Multiple valve diseases
0.692 0.308 0.000
M70-M79 Other soft tissue disorders
0.692 0.308 0.000
Z98 Other postsurgical states
0.691 0.309 0.000
Z36.5 Antenatal screening for isoimmunisation
0.690 0.310 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.690 0.310 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.690 0.310 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.690 0.310 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.690 0.310 0.000
L50-L54 Urticaria and erythema
0.690 0.310 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.689 0.310 0.000
Q60-Q64 Congenital malformations of the urinary system
0.689 0.311 0.000
C16 Malignant neoplasm of stomach
0.689 0.311 0.000
A41 Other septicaemia
0.687 0.313 0.000
D61 Other aplastic anaemias
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.313 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.686 0.314 0.000
R52.2 Other chronic pain
0.686 0.314 0.000
Chapter XXII Codes for special purposes
0.685 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.684 0.315 0.000
K73 Chronic hepatitis, not elsewhere classified
0.684 0.315 0.000
K71 Toxic liver disease
0.684 0.315 0.000
L81 Other disorders of pigmentation
0.684 0.316 0.000
M21.1 Varus deformity, not elsewhere classified
0.683 0.317 0.000
D55-D59 Haemolytic anaemias
0.683 0.317 0.000
L60.8 Other nail disorders
0.683 0.317 0.000
O44 Placenta praevia
0.681 0.319 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.680 0.320 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.680 0.320 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.680 0.320 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.680 0.320 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.680 0.320 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.680 0.320 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.680 0.320 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.680 0.320 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.680 0.320 0.000
F11 Mental and behavioural disorders due to use of opioids
0.680 0.320 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.679 0.320 0.000
C79 Secondary malignant neoplasm of other sites
0.680 0.320 0.000
F28 Other nonorganic psychotic disorders
0.679 0.321 0.000
F24 Induced delusional disorder
0.679 0.321 0.000
F21 Schizotypal disorder
0.679 0.321 0.000
K86.3 Pseudocyst of pancreas
0.678 0.322 0.000
R68 Other general symptoms and signs
0.677 0.323 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.677 0.323 0.000
J80 Adult respiratory distress syndrome
0.675 0.325 0.000
H25-H28 Disorders of lens
0.675 0.325 0.000
F38 Other mood [affective] disorders
0.674 0.325 0.000
F34 Persistent mood [affective] disorders
0.674 0.325 0.000
F30 Manic episode
0.674 0.325 0.000
F39 Unspecified mood [affective] disorder
0.674 0.325 0.000
K04 Diseases of pulp and periapical tissues
0.674 0.326 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.674 0.326 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.674 0.326 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.674 0.326 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.674 0.326 0.000
O41 Other disorders of amniotic fluid and membranes
0.674 0.326 0.000
I05.2 Mitral stenosis with insufficiency
0.672 0.328 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.672 0.328 0.000
D37.7 Other digestive organs
0.671 0.329 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.671 0.329 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.671 0.329 0.000
I49.5 Sick sinus syndrome
0.671 0.329 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.670 0.330 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.669 0.331 0.000
I45 Other conduction disorders
0.669 0.331 0.000
I51.9 Heart disease, unspecified
0.669 0.331 0.000
R52.1 Chronic intractable pain
0.669 0.331 0.000
O36.8 Maternal care for other specified foetal problems
0.669 0.331 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.668 0.332 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.668 0.332 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.667 0.333 0.000
I27.2 Other secondary pulmonary hypertension
0.667 0.333 0.000
D86.0 Sarcoidosis of lung
0.667 0.333 0.000
F31 Bipolar affective disorder
0.667 0.333 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.667 0.333 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.666 0.334 0.000
K12.1 Other forms of stomatitis
0.665 0.335 0.000
O85-O92 Complications predominantly related to the puerperium
0.665 0.335 0.000
K86.9 Disease of pancreas, unspecified
0.665 0.335 0.000
L83 Acanthosis nigricans
0.665 0.335 0.000
M51 Other intervertebral disk disorders
0.663 0.337 0.000
K92.8 Other specified diseases of digestive system
0.663 0.337 0.000
I42.9 Cardiomyopathy, unspecified
0.662 0.338 0.000
F10.9 Unspecified mental and behavioural disorder
0.662 0.338 0.000
F10.8 Other mental and behavioural disorders
0.662 0.338 0.000
F10.7 Residual and late-onset psychotic disorder
0.662 0.338 0.000
F10.6 Amnesic syndrome
0.662 0.338 0.000
F10.5 Psychotic disorder
0.662 0.338 0.000
F10.4 Withdrawal state with delirium
0.662 0.338 0.000
F22 Persistent delusional disorders
0.662 0.338 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.662 0.338 0.000
Q80-Q89 Other congenital malformations
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.662 0.338 0.000
Q35-Q37 Cleft lip and cleft palate
0.662 0.338 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.662 0.338 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.662 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.338 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.662 0.338 0.000
J32 Chronic sinusitis
0.662 0.338 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.661 0.338 0.000
Z87.8 Personal history of other specified conditions
0.661 0.339 0.000
Z39.1 Care and examination of lactating mother
0.660 0.340 0.000
F48 Other neurotic disorders
0.660 0.340 0.000
F44 Dissociative [conversion] disorders
0.660 0.340 0.000
F42 Obsessive-compulsive disorder
0.660 0.340 0.000
M21.9 Acquired deformity of limb, unspecified
0.659 0.340 0.000
M21.8 Other specified acquired deformities of limbs
0.659 0.340 0.000
M21.7 Unequal limb length (acquired)
0.659 0.340 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.659 0.340 0.000
M21.4 Flat foot [pes planus] (acquired)
0.659 0.340 0.000
M21.2 Flexion deformity
0.659 0.340 0.000
J93.1 Other spontaneous pneumothorax
0.659 0.341 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.659 0.341 0.000
J94.2 Haemothorax
0.658 0.342 0.000
K70.1 Alcoholic hepatitis
0.657 0.343 0.000
M54.56 Low back pain (Lumbar region)
0.657 0.343 0.000
Z75 Problems related to medical facilities and other health care
0.656 0.344 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.656 0.344 0.000
F60 Specific personality disorders
0.656 0.344 0.000
O30.0 Twin pregnancy
0.655 0.345 0.000
J98.1 Pulmonary collapse
0.655 0.345 0.000
R25.2 Cramp and spasm
0.655 0.345 0.000
K92.0 Haematemesis
0.654 0.346 0.000
K01.0 Embedded teeth
0.653 0.346 0.000
K07.3 Anomalies of tooth position
0.653 0.347 0.000
I07 Rheumatic tricuspid valve diseases
0.653 0.347 0.000
Z96 Presence of other functional implants
0.652 0.348 0.000
Chapter XIV Diseases of the genitourinary system
0.652 0.348 0.000
L84 Corns and callosities
0.652 0.348 0.000
O36.6 Maternal care for excessive foetal growth
0.651 0.349 0.000
C78.2 Secondary malignant neoplasm of pleura
0.651 0.349 0.000
A41.9 Septicaemia, unspecified
0.651 0.349 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.650 0.350 0.000
K11.9 Disease of salivary gland, unspecified
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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