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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1441756
log Bayes Factor = 18.4586
Chromosome 8   position 19,868,386  (GRCh37) Explore rs1441756 on Ensembl!
Variant rs1441756 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.003 0.997
I22 Subsequent myocardial infarction
0.000 0.005 0.995
I20.0 Unstable angina
0.000 0.007 0.993
E78.5 Hyperlipidaemia, unspecified
0.000 0.012 0.988
E78.2 Mixed hyperlipidaemia
0.000 0.016 0.984
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.021 0.979
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.023 0.977
I24 Other acute ischaemic heart diseases
0.000 0.024 0.976
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.028 0.972
I20.9 Angina pectoris, unspecified
0.000 0.036 0.964
I21.9 Acute myocardial infarction, unspecified
0.000 0.036 0.964
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.036 0.964
I25.4 Coronary artery aneurysm
0.000 0.080 0.920
E78.4 Other hyperlipidaemia
0.000 0.089 0.911
E78.1 Pure hyperglyceridaemia
0.000 0.102 0.898
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.106 0.894
I21.4 Acute subendocardial myocardial infarction
0.000 0.109 0.891
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.110 0.890
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.119 0.881
I77 Other disorders of arteries and arterioles
0.000 0.128 0.872
I73 Other peripheral vascular diseases
0.000 0.131 0.869
I71 Aortic aneurysm and dissection
0.000 0.136 0.864
I73.9 Peripheral vascular disease, unspecified
0.000 0.137 0.863
I77.1 Stricture of artery
0.000 0.139 0.861
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.151 0.849
I70 Atherosclerosis
0.000 0.183 0.817
I25.5 Ischaemic cardiomyopathy
0.000 0.184 0.816
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.204 0.796
I73.8 Other specified peripheral vascular diseases
0.000 0.211 0.789
I71.0 Dissection of aorta [any part]
0.000 0.216 0.784
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.220 0.780
Chapter IX Diseases of the circulatory system
0.000 0.235 0.765
I77.8 Other specified disorders of arteries and arterioles
0.000 0.236 0.764
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.241 0.759
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.247 0.753
I24.8 Other forms of acute ischaemic heart disease
0.000 0.253 0.747
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.265 0.735
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.716
E78.3 Hyperchylomicronaemia
0.000 0.283 0.716
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.292 0.708
I23 Certain current complications following acute myocardial infarction
0.000 0.319 0.681
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.319 0.681
I70.1 Atherosclerosis of renal artery
0.000 0.323 0.677
I77.0 Arteriovenous fistula, acquired
0.000 0.324 0.676
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.329 0.671
E78.6 Lipoprotein deficiency
0.000 0.331 0.669
I77.2 Rupture of artery
0.000 0.340 0.660
I20.1 Angina pectoris with documented spasm
0.000 0.355 0.645
I77.5 Necrosis of artery
0.000 0.374 0.625
I77.4 Coeliac artery compression syndrome
0.000 0.374 0.625
I77.3 Arterial fibromuscular dysplasia
0.000 0.374 0.625
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.381 0.619
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.381 0.619
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.381 0.619
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.381 0.619
I70.0 Atherosclerosis of aorta
0.000 0.394 0.606
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.398 0.602
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.414 0.586
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.417 0.583
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.420 0.580
E78.8 Other disorders of lipoprotein metabolism
0.000 0.424 0.576
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.424 0.576
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.429 0.570
I79.1 Aortitis in diseases classified elsewhere
0.000 0.429 0.570
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.429 0.570
I70.9 Generalised and unspecified atherosclerosis
0.000 0.432 0.568
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.446 0.554
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.449 0.551
I00-I02 Acute rheumatic fever
0.000 0.453 0.547
I24.1 Dressler's syndrome
0.000 0.465 0.534
I70.8 Atherosclerosis of other arteries
0.000 0.484 0.515
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.488 0.512
I25.6 Silent myocardial ischaemia
0.001 0.498 0.501
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.501 0.499
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.511 0.488
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.511 0.488
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.511 0.488
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.511 0.488
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.511 0.488
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.511 0.488
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.511 0.488
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.515 0.485
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.516 0.484
I77.6 Arteritis, unspecified
0.000 0.523 0.477
I22.8 Subsequent myocardial infarction of other sites
0.000 0.529 0.471
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.546 0.454
I23.8 Other current complications following acute myocardial infarction
0.000 0.547 0.453
I25.3 Aneurysm of heart
0.000 0.554 0.446
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.555 0.445
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.565 0.434
I97.1 Other functional disturbances following cardiac surgery
0.000 0.585 0.415
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.592 0.407
I02 Rheumatic chorea
0.000 0.608 0.392
I01 Rheumatic fever with heart involvement
0.000 0.608 0.392
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.610 0.390
I00 Rheumatic fever without mention of heart involvement
0.000 0.610 0.390
I05-I09 Chronic rheumatic heart diseases
0.000 0.620 0.380
I78 Diseases of capillaries
0.000 0.620 0.380
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.630 0.369
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.653 0.347
I97.0 Postcardiotomy syndrome
0.000 0.653 0.347
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.663 0.337
I74 Arterial embolism and thrombosis
0.000 0.671 0.329
I07 Rheumatic tricuspid valve diseases
0.000 0.674 0.326
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.676 0.324
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.682 0.318
I99 Other and unspecified disorders of circulatory system
0.000 0.690 0.310
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.696 0.303
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.701 0.299
I07.1 Tricuspid insufficiency
0.000 0.712 0.287
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.719 0.281
I01.8 Other acute rheumatic heart disease
0.000 0.719 0.281
I01.2 Acute rheumatic myocarditis
0.000 0.719 0.281
I01.1 Acute rheumatic endocarditis
0.000 0.719 0.281
I01.0 Acute rheumatic pericarditis
0.000 0.719 0.281
I02.9 Rheumatic chorea without heart involvement
0.000 0.719 0.281
I02.0 Rheumatic chorea with heart involvement
0.000 0.719 0.281
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.721 0.279
I09 Other rheumatic heart diseases
0.000 0.725 0.275
I74.8 Embolism and thrombosis of other arteries
0.000 0.726 0.274
I78.9 Disease of capillaries, unspecified
0.000 0.727 0.273
I20.8 Other forms of angina pectoris
0.000 0.748 0.252
I05 Rheumatic mitral valve diseases
0.000 0.748 0.252
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.750 0.250
I78.8 Other diseases of capillaries
0.000 0.757 0.243
I28 Other diseases of pulmonary vessels
0.000 0.765 0.235
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.766 0.234
I07.9 Tricuspid valve disease, unspecified
0.000 0.766 0.234
I07.8 Other tricuspid valve diseases
0.000 0.766 0.234
I07.2 Tricuspid stenosis with insufficiency
0.000 0.766 0.234
I07.0 Tricuspid stenosis
0.000 0.766 0.234
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.769 0.231
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.775 0.225
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.775 0.225
I05.1 Rheumatic mitral insufficiency
0.000 0.779 0.221
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.782 0.218
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.782 0.218
I98.0 Cardiovascular syphilis
0.000 0.782 0.218
I06 Rheumatic aortic valve diseases
0.000 0.798 0.202
I09.9 Rheumatic heart disease, unspecified
0.000 0.800 0.200
I09.8 Other specified rheumatic heart diseases
0.000 0.802 0.197
I09.2 Chronic rheumatic pericarditis
0.000 0.802 0.197
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.802 0.197
I09.0 Rheumatic myocarditis
0.000 0.802 0.197
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.811 0.189
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.811 0.189
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.813 0.187
Z95.1 Presence of aortocoronary bypass graft
0.000 0.814 0.186
I74.5 Embolism and thrombosis of iliac artery
0.000 0.816 0.184
I05.8 Other mitral valve diseases
0.000 0.819 0.180
I26 Pulmonary embolism
0.000 0.824 0.175
I05.9 Mitral valve disease, unspecified
0.000 0.826 0.174
I28.8 Other specified diseases of pulmonary vessels
0.000 0.828 0.171
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.830 0.169
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.831 0.169
I28.1 Aneurysm of pulmonary artery
0.000 0.831 0.169
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.831 0.169
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.836 0.164
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.840 0.160
Z95.2 Presence of prosthetic heart valve
0.000 0.841 0.159
I05.0 Mitral stenosis
0.000 0.851 0.149
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.855 0.145
I06.8 Other rheumatic aortic valve diseases
0.000 0.855 0.145
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.855 0.145
I06.1 Rheumatic aortic insufficiency
0.000 0.855 0.144
N90 Other noninflammatory disorders of vulva and perineum
0.000 0.856 0.144
N90.7 Vulvar cyst
0.000 0.858 0.142
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.859 0.141
N90.4 Leukoplakia of vulva
0.000 0.860 0.140
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.000 0.866 0.134
N90.6 Hypertrophy of vulva
0.000 0.868 0.132
N90.5 Atrophy of vulva
0.000 0.868 0.132
I10-I15 Hypertensive diseases
0.000 0.873 0.126
I27 Other pulmonary heart diseases
0.000 0.878 0.122
I06.0 Rheumatic aortic stenosis
0.001 0.880 0.120
I05.2 Mitral stenosis with insufficiency
0.000 0.881 0.118
N90.1 Moderate vulvar dysplasia
0.000 0.884 0.116
I72 Other aneurysm
0.001 0.885 0.114
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.886 0.114
I73.0 Raynaud's syndrome
0.000 0.895 0.105
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.000 0.897 0.103
N90.0 Mild vulvar dysplasia
0.000 0.899 0.101
I08 Multiple valve diseases
0.000 0.903 0.096
I11 Hypertensive heart disease
0.000 0.907 0.092
I08.8 Other multiple valve diseases
0.000 0.911 0.089
I27.1 Kyphoscoliotic heart disease
0.000 0.912 0.088
I15 Secondary hypertension
0.000 0.913 0.087
I27.9 Pulmonary heart disease, unspecified
0.000 0.915 0.085
I27.8 Other specified pulmonary heart diseases
0.000 0.915 0.085
Z95.3 Presence of xenogenic heart valve
0.000 0.916 0.084
I72.9 Aneurysm of unspecified site
0.001 0.916 0.083
I72.6 Aneurysm and dissection of vertebral artery
0.001 0.917 0.082
I72.5 Aneurysm and dissection of other precerebral arteries
0.001 0.917 0.082
I72.2 Aneurysm of renal artery
0.001 0.918 0.081
I78.1 Naevus, nonneoplastic
0.000 0.919 0.081
I13 Hypertensive heart and renal disease
0.000 0.920 0.080
N90.3 Dysplasia of vulva, unspecified
0.000 0.923 0.076
I72.1 Aneurysm of artery of upper extremity
0.001 0.924 0.075
I08.9 Multiple valve disease, unspecified
0.000 0.924 0.076
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.929 0.071
I15.1 Hypertension secondary to other renal disorders
0.000 0.931 0.069
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.000 0.935 0.064
I72.4 Aneurysm of artery of lower extremity
0.001 0.936 0.063
I95 Hypotension
0.000 0.936 0.064
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.936 0.063
I27.0 Primary pulmonary hypertension
0.000 0.937 0.063
I15.8 Other secondary hypertension
0.000 0.937 0.062
I15.2 Hypertension secondary to endocrine disorders
0.000 0.937 0.062
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.942 0.057
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.942 0.057
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.942 0.057
I15.0 Renovascular hypertension
0.000 0.943 0.057
I15.9 Seconday hypertension, unspecified
0.000 0.944 0.056
I72.3 Aneurysm of iliac artery
0.001 0.947 0.051
I27.2 Other secondary pulmonary hypertension
0.000 0.949 0.051
I95.8 Other hypotension
0.000 0.953 0.047
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.954 0.046
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.954 0.046
I72.8 Aneurysm of other specified arteries
0.002 0.954 0.045
I72.0 Aneurysm of carotid artery
0.002 0.955 0.043
I95.0 Idiopathic hypotension
0.000 0.957 0.043
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.958 0.041
Z95.4 Presence of other heart-valve replacement
0.000 0.963 0.037
I12 Hypertensive renal disease
0.000 0.967 0.033
I08.0 Disorders of both mitral and aortic valves
0.000 0.977 0.023
I95.1 Orthostatic hypotension
0.000 0.977 0.023
I95.2 Hypotension due to drugs
0.000 0.980 0.019
E11.5 With peripheral circulatory complications
0.000 0.987 0.013
E11.9 Without complications
0.000 0.987 0.013
E11 Non-insulin-dependent diabetes mellitus
0.000 0.987 0.013
E11.3 With ophthalmic complications
0.000 0.988 0.012
E11.1 With ketoacidosis
0.000 0.989 0.011
I95.9 Hypotension, unspecified
0.000 0.989 0.011
E11.8 With unspecified complications
0.000 0.990 0.010
E70-E90 Metabolic disorders
0.000 0.990 0.010
I12.9 Hypertensive renal disease without renal failure
0.000 0.990 0.009
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.990 0.009
E11.7 With multiple complications
0.000 0.991 0.009
E11.0 With coma
0.000 0.991 0.009
E11.2 With renal complications
0.000 0.991 0.009
E85 Amyloidosis
0.000 0.991 0.009
E73 Lactose intolerance
0.000 0.991 0.009
E79 Disorders of purine and pyrimidine metabolism
0.000 0.992 0.008
E73.9 Lactose intolerance, unspecified
0.000 0.992 0.008
E84 Cystic fibrosis
0.000 0.992 0.008
E11.6 With other specified complications
0.000 0.992 0.008
E85.4 Organ-limited amyloidosis
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.000 0.992 0.007
E76 Disorders of glycosaminoglycan metabolism
0.000 0.992 0.007
E72 Other disorders of amino-acid metabolism
0.000 0.992 0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.992 0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.992 0.007
E74 Other disorders of carbohydrate metabolism
0.000 0.992 0.007
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.992 0.007
E85.3 Secondary systemic amyloidosis
0.000 0.993 0.007
C02.1 Border of tongue
0.007 0.993 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.993 0.007
I81 Portal vein thrombosis
0.000 0.993 0.007
I83 Varicose veins of lower extremities
0.000 0.993 0.007
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.993 0.007
S20.8 Superficial injuries of other and unspecified parts of thorax
0.007 0.993 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.993 0.007
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.993 0.007
C02 Malignant neoplasm of other and unspecified parts of tongue
0.007 0.993 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.993 0.007
I87 Other disorders of veins
0.000 0.993 0.007
E85.9 Amyloidosis, unspecified
0.000 0.993 0.007
E85.8 Other amyloidosis
0.000 0.993 0.007
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.993 0.007
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.000 0.993 0.007
E73.1 Secondary lactase deficiency
0.000 0.993 0.007
E73.0 Congenital lactase deficiency
0.000 0.993 0.007
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.993 0.007
I87.1 Compression of vein
0.000 0.993 0.007
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.993 0.007
E84.9 Cystic fibrosis, unspecified
0.000 0.994 0.006
R16.1 Splenomegaly, not elsewhere classified
0.006 0.994 0.000
S06.2 Diffuse brain injury
0.000 0.994 0.006
J36 Peritonsillar abscess
0.006 0.994 0.000
C00.0 External upper lip
0.006 0.994 0.000
C02.9 Tongue, unspecified
0.006 0.994 0.000
I88 Nonspecific lymphadenitis
0.000 0.994 0.006
C00 Malignant neoplasm of lip
0.006 0.994 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.994 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.994 0.006
E79.1 Lesch-Nyhan syndrome
0.000 0.994 0.006
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.006 0.994 0.000
W19.4 Street and highway
0.006 0.994 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.994 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.994 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.994 0.006
C06 Malignant neoplasm of other and unspecified parts of mouth
0.006 0.994 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.994 0.006
C06.0 Cheek mucosa
0.006 0.994 0.000
E11.4 With neurological complications
0.000 0.994 0.006
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.994 0.006
I85 Oesophageal varices
0.000 0.994 0.006
S06 Intracranial injury
0.000 0.994 0.006
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.994 0.006
E71.3 Disorders of fatty-acid metabolism
0.000 0.994 0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.994 0.006
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.994 0.006
E71.0 Maple-syrup-urine disease
0.000 0.994 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.994 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.994 0.006
E72.5 Disorders of glycine metabolism
0.000 0.994 0.006
E72.4 Disorders of ornithine metabolism
0.000 0.994 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.994 0.006
E72.2 Disorders of urea cycle metabolism
0.000 0.994 0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.994 0.006
E72.0 Disorders of amino-acid transport
0.000 0.994 0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.994 0.006
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.994 0.006
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.994 0.006
E76.2 Other mucopolysaccharidoses
0.000 0.994 0.006
E76.1 Mucopolysaccharidosis, type II
0.000 0.994 0.006
E76.0 Mucopolysaccharidosis, type I
0.000 0.994 0.006
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.994 0.006
E77.8 Other disorders of glycoprotein metabolism
0.000 0.994 0.006
E77.1 Defects in glycoprotein degradation
0.000 0.994 0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.994 0.006
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.994 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.994 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.994 0.005
E74.2 Disorders of galactose metabolism
0.000 0.994 0.005
E74.1 Disorders of fructose metabolism
0.000 0.994 0.005
E74.0 Glycogen storage disease
0.000 0.994 0.005
S06.3 Focal brain injury
0.000 0.994 0.006
C02.2 Ventral surface of tongue
0.006 0.994 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.994 0.005
E88 Other metabolic disorders
0.000 0.995 0.005
E75.6 Lipid storage disorder, unspecified
0.000 0.995 0.005
E75.5 Other lipid storage disorders
0.000 0.995 0.005
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.995 0.005
E75.3 Sphingolipidosis, unspecified
0.000 0.995 0.005
E75.1 Other gangliosidosis
0.000 0.995 0.005
E75.0 GM2 gangliosidosis
0.000 0.995 0.005
I51.9 Heart disease, unspecified
0.000 0.995 0.005
C02.8 Overlapping lesion of tongue
0.005 0.995 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.005 0.995 0.000
C02.0 Dorsal surface of tongue
0.005 0.995 0.000
C07 Malignant neoplasm of parotid gland
0.005 0.995 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.995 0.005
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.995 0.005
E70.2 Disorders of tyrosine metabolism
0.000 0.995 0.005
E70.1 Other hyperphenylalaninaemias
0.000 0.995 0.005
E70.0 Classical phenylketonuria
0.000 0.995 0.005
I87.9 Disorder of vein, unspecified
0.000 0.995 0.005
I87.0 Postphlebitic syndrome
0.000 0.995 0.005
C02.4 Lingual tonsil
0.005 0.995 0.000
C03 Malignant neoplasm of gum
0.005 0.995 0.000
G50.0 Trigeminal neuralgia
0.000 0.995 0.005
S06.8 Other intracranial injuries
0.000 0.995 0.005
S20.2 Contusion of thorax
0.005 0.995 0.000
C06.2 Retromolar area
0.005 0.995 0.000
S06.5 Traumatic subdural haemorrhage
0.000 0.995 0.005
C00.9 Lip, unspecified
0.005 0.995 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.995 0.005
Z95.0 Presence of cardiac pacemaker
0.000 0.995 0.005
M07.30 Other psoriatic arthropathies (Multiple sites)
0.005 0.995 0.000
I87.8 Other specified disorders of veins
0.000 0.995 0.005
C04 Malignant neoplasm of floor of mouth
0.005 0.995 0.000
C00.1 External lower lip
0.005 0.995 0.000
E75.2 Other sphingolipidosis
0.000 0.995 0.005
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.995 0.005
C10 Malignant neoplasm of oropharynx
0.005 0.995 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.995 0.005
C00.8 Overlapping lesion of lip
0.005 0.995 0.000
C00.6 Commissure of lip
0.005 0.995 0.000
C00.5 Lip, unspecified, inner aspect
0.005 0.995 0.000
C00.4 Lower lip, inner aspect
0.005 0.995 0.000
C00.3 Upper lip, inner aspect
0.005 0.995 0.000
C00.2 External lip, unspecified
0.005 0.995 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.995 0.005
S06.9 Intracranial injury, unspecified
0.000 0.995 0.005
S20 Superficial injury of thorax
0.005 0.995 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.005 0.995 0.000
S06.4 Epidural haemorrhage
0.000 0.995 0.005
C13 Malignant neoplasm of hypopharynx
0.005 0.995 0.000
I60-I69 Cerebrovascular diseases
0.000 0.995 0.005
C06.9 Mouth, unspecified
0.004 0.995 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.004 0.995 0.000
C06.1 Vestibule of mouth
0.004 0.995 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.995 0.005
C11 Malignant neoplasm of nasopharynx
0.004 0.995 0.000
C03.1 Lower gum
0.004 0.995 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.995 0.004
E70.3 Albinism
0.000 0.995 0.004
I88.8 Other nonspecific lymphadenitis
0.000 0.995 0.004
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.995 0.004
C05 Malignant neoplasm of palate
0.004 0.995 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.996 0.004
S06.7 Intracranial injury with prolonged coma
0.000 0.996 0.004
S06.1 Traumatic cerebral oedema
0.000 0.996 0.004
G91.9 Hydrocephalus, unspecified
0.004 0.996 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.996 0.004
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.996 0.004
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.996 0.004
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.004 0.996 0.000
I84.4 External haemorrhoids with other complications
0.000 0.996 0.004
I85.9 Oesophageal varices without bleeding
0.000 0.996 0.004
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.996 0.004
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.996 0.004
C09 Malignant neoplasm of tonsil
0.004 0.996 0.000
C04.9 Floor of mouth, unspecified
0.004 0.996 0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.000 0.996 0.004
C03.9 Gum, unspecified
0.004 0.996 0.000
C03.0 Upper gum
0.004 0.996 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.996 0.004
E88.3 Tumour lysis syndrome
0.000 0.996 0.004
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.004 0.996 0.000
I63 Cerebral infarction
0.000 0.996 0.004
E88.2 Lipomatosis, not elsewhere classified
0.000 0.996 0.004
E80.2 Other porphyria
0.000 0.996 0.004
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.996 0.004
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.996 0.004
E88.8 Other specified metabolic disorders
0.000 0.996 0.004
Y60.0 During surgical operation
0.004 0.996 0.000
C12 Malignant neoplasm of pyriform sinus
0.004 0.996 0.000
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.996 0.004
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.996 0.004
M07.3 Other psoriatic arthropathies
0.004 0.996 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.996 0.004
E88.9 Metabolic disorder, unspecified
0.000 0.996 0.004
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.996 0.004
C10.9 Oropharynx, unspecified
0.004 0.996 0.000
T40.4 Other synthetic narcotics
0.000 0.996 0.004
C04.8 Overlapping lesion of floor of mouth
0.004 0.996 0.000
C04.1 Lateral floor of mouth
0.004 0.996 0.000
C04.0 Anterior floor of mouth
0.004 0.996 0.000
C08.0 Submandibular gland
0.004 0.996 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.996 0.004
C05.0 Hard palate
0.004 0.996 0.000
C10.8 Overlapping lesion of oropharynx
0.004 0.996 0.000
C10.4 Branchial cleft
0.004 0.996 0.000
C10.3 Posterior wall of oropharynx
0.004 0.996 0.000
C10.2 Lateral wall of oropharynx
0.004 0.996 0.000
C10.1 Anterior surface of epiglottis
0.004 0.996 0.000
C10.0 Vallecula
0.004 0.996 0.000
E80.5 Crigler-Najjar syndrome
0.000 0.996 0.003
E80.3 Defects of catalase and peroxydase
0.000 0.996 0.003
E80.0 Hereditary erythropoietic porphyria
0.000 0.996 0.003
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.000 0.996 0.003
N34.2 Other urethritis
0.004 0.996 0.000
S20.7 Multiple superficial injuries of thorax
0.004 0.996 0.000
S20.0 Contusion of breast
0.004 0.996 0.000
C08.8 Overlapping lesion of major salivary glands
0.003 0.996 0.000
C08.1 Sublingual gland
0.003 0.996 0.000
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.996 0.003
C13.9 Hypopharynx, unspecified
0.003 0.996 0.000
C13.8 Overlapping lesion of hypopharynx
0.003 0.996 0.000
C13.2 Posterior wall of hypopharynx
0.003 0.996 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.003 0.996 0.000
C13.0 Postcricoid region
0.003 0.996 0.000
C11.8 Overlapping lesion of nasopharynx
0.003 0.996 0.000
C11.3 Anterior wall of nasopharynx
0.003 0.996 0.000
C11.2 Lateral wall of nasopharynx
0.003 0.996 0.000
C11.1 Posterior wall of nasopharynx
0.003 0.996 0.000
C11.0 Superior wall of nasopharynx
0.003 0.996 0.000
T40.2 Other opioids
0.000 0.996 0.004
C05.1 Soft palate
0.003 0.996 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.996 0.003
C05.8 Overlapping lesion of palate
0.003 0.996 0.000
C05.2 Uvula
0.003 0.996 0.000
S20.1 Other and unspecified superficial injuries of breast
0.003 0.996 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.997 0.003
C08.9 Major salivary gland, unspecified
0.003 0.997 0.000
C11.9 Nasopharynx, unspecified
0.003 0.997 0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.000 0.997 0.003
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.000 0.997 0.003
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.997 0.003
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.997 0.003
Z13.6 Special screening examination for cardiovascular disorders
0.003 0.997 0.000
C01 Malignant neoplasm of base of tongue
0.003 0.997 0.000
E80.1 Porphyria cutanea tarda
0.000 0.997 0.003
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.003 0.997 0.000
C14.2 Waldeyer's ring
0.003 0.997 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.000 0.997 0.003
S06.0 Concussion
0.000 0.997 0.003
I85.0 Oesophageal varices with bleeding
0.000 0.997 0.003
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.997 0.003
S20.4 Other superficial injuries of back wall of thorax
0.003 0.997 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.997 0.003
D13.2 Duodenum
0.000 0.997 0.003
E80.4 Gilbert's syndrome
0.000 0.997 0.003
C09.8 Overlapping lesion of tonsil
0.003 0.997 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.003 0.997 0.000
C09.0 Tonsillar fossa
0.003 0.997 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.997 0.003
I63.8 Other cerebral infarction
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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