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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs144191434
log Bayes Factor = 3.26906
Chromosome 22   position 20,004,100  (GRCh37) Explore rs144191434 on Ensembl!
Variant rs144191434 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
K40-K46 Hernia
0.976 0.024 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.970 0.030 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.967 0.033 0.000
Chapter XXI Factors influencing health status and contact with health services
0.965 0.035 0.000
Chapter VII Diseases of the eye and adnexa
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.941 0.059 0.000
K90-K93 Other diseases of the digestive system
0.940 0.060 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.939 0.061 0.000
K44 Diaphragmatic hernia
0.930 0.070 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.930 0.070 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.916 0.084 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.914 0.086 0.000
K92 Other diseases of digestive system
0.905 0.095 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.903 0.097 0.000
Chapter II Neoplasms
0.902 0.098 0.000
Z48 Other surgical follow-up care
0.901 0.099 0.000
K40 Inguinal hernia
0.899 0.101 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.898 0.102 0.000
S00-S09 Injuries to the head
0.898 0.102 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.894 0.106 0.000
M20-M25 Other joint disorders
0.888 0.112 0.000
Z96 Presence of other functional implants
0.887 0.113 0.000
M15-M19 Arthrosis
0.877 0.123 0.000
K92.0 Haematemesis
0.862 0.138 0.000
H40-H42 Glaucoma
0.862 0.138 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.861 0.139 0.000
Z50 Care involving use of rehabilitation procedures
0.859 0.141 0.000
Chapter VI Diseases of the nervous system
0.857 0.143 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.847 0.153 0.000
O60-O75 Complications of labour and delivery
0.845 0.155 0.000
Z80 Family history of malignant neoplasm
0.843 0.157 0.000
Z48.8 Other specified surgical follow-up care
0.843 0.157 0.000
E65-E68 Obesity and other hyperalimentation
0.842 0.158 0.000
Z96.1 Presence of intraocular lens
0.836 0.164 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.836 0.164 0.000
K42 Umbilical hernia
0.828 0.172 0.000
H65-H75 Diseases of middle ear and mastoid
0.825 0.175 0.000
H60-H62 Diseases of external ear
0.820 0.180 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.812 0.188 0.000
S01 Open wound of head
0.811 0.189 0.000
Z96.0 Presence of urogenital implants
0.806 0.194 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.806 0.194 0.000
Chapter I Certain infectious and parasitic diseases
0.803 0.197 0.000
Z51 Other medical care
0.802 0.198 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.802 0.198 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.800 0.200 0.000
H40 Glaucoma
0.797 0.203 0.000
S60-S69 Injuries to the wrist and hand
0.795 0.205 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.786 0.213 0.000
Z48.0 Attention to surgical dressings and sutures
0.781 0.219 0.000
M25 Other joint disorders, not elsewhere classified
0.779 0.221 0.000
E66 Obesity
0.779 0.221 0.000
K50-K52 Noninfective enteritis and colitis
0.775 0.225 0.000
Z51.0 Radiotherapy session
0.770 0.230 0.000
E20-E35 Disorders of other endocrine glands
0.768 0.232 0.000
M16 Coxarthrosis [arthrosis of hip]
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.762 0.238 0.000
K11 Diseases of salivary glands
0.761 0.239 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.761 0.239 0.000
H30-H36 Disorders of choroid and retina
0.760 0.240 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.759 0.241 0.000
E50-E64 Other nutritional deficiencies
0.752 0.248 0.000
S06 Intracranial injury
0.745 0.255 0.000
S01.8 Open wound of other parts of head
0.744 0.256 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.743 0.257 0.000
T39.1 4-Aminophenol derivatives
0.743 0.257 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.742 0.258 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.741 0.259 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.740 0.260 0.000
H53-H54 Visual disturbances and blindness
0.738 0.262 0.000
K92.1 Melaena
0.738 0.262 0.000
Z50.1 Other physical therapy
0.736 0.264 0.000
C51-C58 Malignant neoplasms of female genital organs
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.731 0.269 0.000
M18 Arthrosis of first carpometacarpal joint
0.731 0.269 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.730 0.270 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.727 0.273 0.000
E10-E14 Diabetes mellitus
0.726 0.274 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.725 0.275 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
H40.0 Glaucoma suspect
0.723 0.277 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.723 0.277 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.722 0.278 0.000
K90 Intestinal malabsorption
0.722 0.278 0.000
M23 Internal derangement of knee
0.722 0.278 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.722 0.278 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.721 0.279 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.720 0.279 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.715 0.285 0.000
M50-M54 Other dorsopathies
0.711 0.289 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.710 0.289 0.000
H80-H83 Diseases of inner ear
0.710 0.290 0.000
M40-M43 Deforming dorsopathies
0.709 0.291 0.000
Z80.3 Family history of malignant neoplasm of breast
0.707 0.293 0.000
Z83 Family history of other specific disorders
0.707 0.293 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.706 0.294 0.000
M45-M49 Spondylopathies
0.705 0.295 0.000
E66.9 Obesity, unspecified
0.705 0.295 0.000
M70-M79 Other soft tissue disorders
0.703 0.297 0.000
Chapter XX External causes of morbidity and mortality
0.703 0.297 0.000
M80-M85 Disorders of bone density and structure
0.703 0.297 0.000
T66-T78 Other and unspecified effects of external causes
0.702 0.297 0.000
Z96.6 Presence of orthopaedic joint implants
0.701 0.299 0.000
Z43 Attention to artificial openings
0.701 0.299 0.000
K46 Unspecified abdominal hernia
0.700 0.300 0.000
K45 Other abdominal hernia
0.700 0.300 0.000
H90-H95 Other disorders of ear
0.699 0.301 0.000
K14 Diseases of tongue
0.698 0.302 0.000
K04 Diseases of pulp and periapical tissues
0.698 0.302 0.000
K41 Femoral hernia
0.697 0.303 0.000
C50-C50 Malignant neoplasm of breast
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.304 0.000
M91-M94 Chondropathies
0.695 0.304 0.000
M60-M63 Disorders of muscles
0.695 0.304 0.000
M00-M03 Infectious arthropathies
0.695 0.304 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.695 0.305 0.000
H66 Suppurative and unspecified otitis media
0.695 0.305 0.000
M21 Other acquired deformities of limbs
0.694 0.305 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.694 0.306 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.694 0.306 0.000
T79-T79 Certain early complications of trauma
0.694 0.306 0.000
T33-T35 Frostbite
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.694 0.306 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.694 0.306 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.694 0.306 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.694 0.306 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
T00-T07 Injuries involving multiple body regions
0.694 0.306 0.000
S90-S99 Injuries to the ankle and foot
0.694 0.306 0.000
S10-S19 Injuries to the neck
0.694 0.306 0.000
M17 Gonarthrosis [arthrosis of knee]
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.691 0.309 0.000
C77.3 Axillary and upper limb lymph nodes
0.690 0.310 0.000
Z97 Presence of other devices
0.690 0.310 0.000
S00 Superficial injury of head
0.689 0.311 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
H49 Paralytic strabismus
0.688 0.312 0.000
B95-B98 Bacterial, viral and other infectious agents
0.688 0.312 0.000
D10-D36 Benign neoplasms
0.687 0.313 0.000
M22 Disorders of patella
0.687 0.313 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.687 0.313 0.000
Z46 Fitting and adjustment of other devices
0.686 0.314 0.000
K43 Ventral hernia
0.686 0.314 0.000
L20-L30 Dermatitis and eczema
0.684 0.316 0.000
H55-H59 Other disorders of eye and adnexa
0.684 0.316 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.684 0.316 0.000
H10-H13 Disorders of conjunctiva
0.684 0.316 0.000
H60 Otitis externa
0.684 0.316 0.000
H52 Disorders of refraction and accommodation
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.681 0.319 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.679 0.320 0.000
Z91.5 Personal history of self-harm
0.678 0.322 0.000
S02 Fracture of skull and facial bones
0.677 0.323 0.000
K08 Other disorders of teeth and supporting structures
0.677 0.323 0.000
S62 Fracture at wrist and hand level
0.677 0.323 0.000
H50 Other strabismus
0.676 0.324 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.674 0.326 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.674 0.326 0.000
Z54 Convalescence
0.673 0.327 0.000
Z52 Donors of organs and tissues
0.673 0.327 0.000
Z49 Care involving dialysis
0.673 0.327 0.000
Z44 Fitting and adjustment of external prosthetic device
0.673 0.327 0.000
K02 Dental caries
0.672 0.327 0.000
M20 Acquired deformities of fingers and toes
0.672 0.328 0.000
H61 Other disorders of external ear
0.672 0.328 0.000
C60-C63 Malignant neoplasms of male genital organs
0.671 0.329 0.000
M25.5 Pain in joint
0.671 0.329 0.000
K51 Ulcerative colitis
0.671 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
M16.1 Other primary coxarthrosis
0.669 0.331 0.000
O00-O08 Pregnancy with abortive outcome
0.668 0.332 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.668 0.332 0.000
K44.1 Diaphragmatic hernia with gangrene
0.667 0.333 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.667 0.333 0.000
Z50.5 Speech therapy
0.667 0.333 0.000
E40-E46 Malnutrition
0.667 0.333 0.000
K05 Gingivitis and periodontal diseases
0.663 0.337 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.662 0.338 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.662 0.338 0.000
G40-G47 Episodic and paroxysmal disorders
0.661 0.339 0.000
K11.2 Sialoadenitis
0.659 0.341 0.000
K12 Stomatitis and related lesions
0.659 0.341 0.000
Z86 Personal history of certain other diseases
0.659 0.341 0.000
Z41 Procedures for purposes other than remedying health state
0.658 0.342 0.000
O70 Perineal laceration during delivery
0.657 0.343 0.000
E27 Other disorders of adrenal gland
0.657 0.343 0.000
O85-O92 Complications predominantly related to the puerperium
0.657 0.343 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.657 0.343 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.657 0.343 0.000
Z89 Acquired absence of limb
0.655 0.345 0.000
Z84 Family history of other conditions
0.655 0.345 0.000
Z81 Family history of mental and behavioural disorders
0.655 0.345 0.000
O63 Long labour
0.655 0.345 0.000
C15-C26 Malignant neoplasms of digestive organs
0.655 0.345 0.000
C79 Secondary malignant neoplasm of other sites
0.651 0.349 0.000
S40-S49 Injuries to the shoulder and upper arm
0.649 0.351 0.000
K92.9 Disease of digestive system, unspecified
0.649 0.351 0.000
K92.8 Other specified diseases of digestive system
0.649 0.351 0.000
M17.9 Gonarthrosis, unspecified
0.649 0.351 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.648 0.351 0.000
H65 Nonsuppurative otitis media
0.648 0.352 0.000
K35-K38 Diseases of appendix
0.648 0.352 0.000
K10 Other diseases of jaws
0.647 0.352 0.000
K09 Cysts of oral region, not elsewhere classified
0.647 0.352 0.000
K07 Dentofacial anomalies [including malocclusion]
0.647 0.352 0.000
K03 Other diseases of hard tissues of teeth
0.647 0.352 0.000
K00 Disorders of tooth development and eruption
0.647 0.352 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.647 0.353 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.647 0.353 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.647 0.353 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.647 0.353 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.647 0.353 0.000
Z48.9 Surgical follow-up care, unspecified
0.646 0.354 0.000
K70-K77 Diseases of liver
0.646 0.354 0.000
Z51.8 Other specified medical care
0.646 0.354 0.000
M05-M14 Inflammatory polyarthropathies
0.645 0.355 0.000
E66.8 Other obesity
0.645 0.355 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.645 0.355 0.000
L40-L45 Papulosquamous disorders
0.645 0.355 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.644 0.356 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.644 0.356 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.644 0.356 0.000
Z92 Personal history of medical treatment
0.644 0.356 0.000
Z51.3 Blood transfusion without reported diagnosis
0.644 0.356 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.644 0.356 0.000
S08 Traumatic amputation of part of head
0.644 0.356 0.000
S07 Crushing injury of head
0.644 0.356 0.000
S05 Injury of eye and orbit
0.644 0.356 0.000
S04 Injury of cranial nerves
0.644 0.356 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.644 0.356 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.643 0.357 0.000
E00-E07 Disorders of thyroid gland
0.643 0.357 0.000
Z94 Transplanted organ and tissue status
0.642 0.358 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.641 0.359 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.641 0.359 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.641 0.359 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.641 0.359 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.641 0.359 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.641 0.359 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.641 0.359 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.641 0.359 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.641 0.359 0.000
T36 Poisoning by systemic antibiotics
0.641 0.359 0.000
Z40 Prophylactic surgery
0.641 0.359 0.000
Z50.8 Care involving use of rehabilitation procedures
0.640 0.360 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.640 0.360 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.639 0.361 0.000
C54 Malignant neoplasm of corpus uteri
0.638 0.361 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.636 0.363 0.000
M34 Systemic sclerosis
0.636 0.363 0.000
M33 Dermatopolymyositis
0.636 0.363 0.000
M32 Systemic lupus erythematosus
0.636 0.363 0.000
M31 Other necrotising vasculopathies
0.636 0.363 0.000
M30 Polyarteritis nodosa and related conditions
0.636 0.363 0.000
O80-O84 Delivery
0.636 0.363 0.000
Z96.9 Presence of functional implant, unspecified
0.636 0.364 0.000
Z96.7 Presence of other bone and tendon implants
0.636 0.364 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.636 0.364 0.000
Z96.4 Presence of endocrine implants
0.636 0.364 0.000
Z96.3 Presence of artificial larynx
0.636 0.364 0.000
Z96.2 Presence of otological and audiological implants
0.636 0.364 0.000
M24 Other specific joint derangements
0.635 0.365 0.000
Z98 Other postsurgical states
0.635 0.365 0.000
H43-H45 Disorders of vitreous body and globe
0.634 0.366 0.000
Z42 Follow-up care involving plastic surgery
0.633 0.366 0.000
H71 Cholesteatoma of middle ear
0.633 0.366 0.000
S80-S89 Injuries to the knee and lower leg
0.633 0.367 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.631 0.368 0.000
M23.3 Other meniscus derangements
0.630 0.370 0.000
M15 Polyarthrosis
0.629 0.371 0.000
G62 Other polyneuropathies
0.626 0.373 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.626 0.374 0.000
K13 Other diseases of lip and oral mucosa
0.625 0.375 0.000
E53 Deficiency of other B group vitamins
0.625 0.375 0.000
A30-A49 Other bacterial diseases
0.625 0.375 0.000
D17 Benign lipomatous neoplasm
0.624 0.376 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.623 0.377 0.000
E14 Unspecified diabetes mellitus
0.623 0.377 0.000
H34 Retinal vascular occlusions
0.623 0.377 0.000
S01.9 Open wound of head, part unspecified
0.621 0.378 0.000
K65-K67 Diseases of peritoneum
0.621 0.379 0.000
H42 Glaucoma in diseases classified elsewhere
0.618 0.382 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.618 0.382 0.000
Z91.7 Personal history of female genital mutilation
0.618 0.382 0.000
Z91.6 Personal history of other physical trauma
0.618 0.382 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.618 0.382 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.618 0.382 0.000
Z91.2 Personal history of poor personal hygiene
0.618 0.382 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.618 0.382 0.000
Z50.6 Orthoptic training
0.616 0.384 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.616 0.384 0.000
Z50.3 Drug rehabilitation
0.616 0.384 0.000
Z50.2 Alcohol rehabilitation
0.616 0.384 0.000
Z50.0 Cardiac rehabilitation
0.616 0.384 0.000
G70-G73 Diseases of myoneural junction and muscle
0.614 0.385 0.000
G30-G32 Other degenerative diseases of the nervous system
0.614 0.385 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.614 0.385 0.000
Z45 Adjustment and management of implanted device
0.614 0.386 0.000
L50-L54 Urticaria and erythema
0.614 0.386 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.614 0.386 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.614 0.386 0.000
H40.2 Primary angle-closure glaucoma
0.612 0.388 0.000
Z72 Problems related to lifestyle
0.610 0.390 0.000
T43.2 Other and unspecified antidepressants
0.610 0.390 0.000
B25-B34 Other viral diseases
0.610 0.390 0.000
M25.56 Pain in joint (Lower leg)
0.609 0.391 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.608 0.392 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.608 0.392 0.000
H51 Other disorders of binocular movement
0.607 0.393 0.000
H40.9 Glaucoma, unspecified
0.606 0.394 0.000
S06.5 Traumatic subdural haemorrhage
0.606 0.394 0.000
O74 Complications of anaesthesia during labour and delivery
0.606 0.394 0.000
O73 Retained placenta and membranes, without haemorrhage
0.606 0.394 0.000
O71 Other obstetric trauma
0.606 0.394 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.606 0.394 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.606 0.394 0.000
O66 Other obstructed labour
0.606 0.394 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.606 0.394 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.606 0.394 0.000
O62 Abnormalities of forces of labour
0.606 0.394 0.000
O61 Failed induction of labour
0.606 0.394 0.000
O60 Preterm delivery
0.606 0.394 0.000
M25.4 Effusion of joint
0.606 0.394 0.000
S50-S59 Injuries to the elbow and forearm
0.605 0.395 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.605 0.395 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.605 0.395 0.000
Z80.6 Family history of leukaemia
0.605 0.395 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.605 0.395 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.605 0.395 0.000
E67 Other hyperalimentation
0.604 0.396 0.000
E68 Sequelae of hyperalimentation
0.604 0.396 0.000
E65 Localised adiposity
0.604 0.396 0.000
D80-D89 Certain disorders involving the immune mechanism
0.603 0.397 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.602 0.398 0.000
H66.9 Otitis media, unspecified
0.601 0.399 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.600 0.400 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.600 0.400 0.000
C80 Malignant neoplasm without specification of site
0.599 0.401 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.599 0.401 0.000
M16.0 Primary coxarthrosis, bilateral
0.598 0.402 0.000
Z51.5 Palliative care
0.598 0.402 0.000
C77.2 Intra-abdominal lymph nodes
0.597 0.403 0.000
G90-G99 Other disorders of the nervous system
0.596 0.404 0.000
H73 Other disorders of tympanic membrane
0.595 0.405 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.594 0.406 0.000
K42.1 Umbilical hernia with gangrene
0.594 0.406 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.594 0.406 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.594 0.406 0.000
S62.6 Fracture of other finger
0.592 0.408 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.591 0.408 0.000
H74 Other disorders of middle ear and mastoid
0.591 0.408 0.000
H70 Mastoiditis and related conditions
0.591 0.408 0.000
H69 Other disorders of Eustachian tube
0.591 0.408 0.000
H68 Eustachian salpingitis and obstruction
0.591 0.408 0.000
H67 Otitis media in diseases classified elsewhere
0.591 0.408 0.000
E10 Insulin-dependent diabetes mellitus
0.591 0.409 0.000
C77.5 Intrapelvic lymph nodes
0.591 0.409 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.591 0.409 0.000
H40.1 Primary open-angle glaucoma
0.590 0.410 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.588 0.412 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.587 0.413 0.000
Z83.3 Family history of diabetes mellitus
0.586 0.414 0.000
M65 Synovitis and tenosynovitis
0.586 0.414 0.000
H54 Blindness and low vision
0.586 0.414 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.585 0.415 0.000
O42 Premature rupture of membranes
0.583 0.416 0.000
H72 Perforation of tympanic membrane
0.582 0.418 0.000
S01.7 Multiple open wounds of head
0.581 0.418 0.000
S01.4 Open wound of cheek and temporomandibular area
0.581 0.418 0.000
S01.3 Open wound of ear
0.581 0.418 0.000
S01.2 Open wound of nose
0.581 0.418 0.000
S01.1 Open wound of eyelid and periocular area
0.581 0.418 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.581 0.419 0.000
S01.5 Open wound of lip and oral cavity
0.580 0.419 0.000
M25.7 Osteophyte
0.579 0.421 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.578 0.421 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.578 0.422 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.578 0.422 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.578 0.422 0.000
T39.4 Antirheumatics, not elsewhere classified
0.578 0.422 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.578 0.422 0.000
T39.2 Pyrazolone derivatives
0.578 0.422 0.000
T39.0 Salicylates
0.578 0.422 0.000
S68 Traumatic amputation of wrist and hand
0.577 0.422 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.577 0.423 0.000
B99-B99 Other infectious diseases
0.576 0.424 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.576 0.424 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.576 0.424 0.000
B65-B83 Helminthiases
0.576 0.424 0.000
B50-B64 Protozoal diseases
0.576 0.424 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.576 0.424 0.000
B15-B19 Viral hepatitis
0.576 0.424 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.576 0.424 0.000
A80-A89 Viral infections of the central nervous system
0.576 0.424 0.000
A75-A79 Rickettsioses
0.576 0.424 0.000
A70-A74 Other diseases caused by chlamydiae
0.576 0.424 0.000
A65-A69 Other spirochaetal diseases
0.576 0.424 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.576 0.424 0.000
A20-A28 Certain zoonotic bacterial diseases
0.576 0.424 0.000
A15-A19 Tuberculosis
0.576 0.424 0.000
Z51.9 Medical care, unspecified
0.575 0.425 0.000
Z51.6 Desensitisation to allergens
0.575 0.425 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.575 0.425 0.000
H49.0 Third [oculomotor] nerve palsy
0.575 0.425 0.000
O72 Postpartum haemorrhage
0.575 0.425 0.000
L10-L14 Bullous disorders
0.573 0.426 0.000
D00-D09 In situ neoplasms
0.573 0.427 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.573 0.427 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.573 0.427 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.572 0.428 0.000
H25-H28 Disorders of lens
0.572 0.428 0.000
H40.8 Other glaucoma
0.571 0.429 0.000
H40.6 Glaucoma secondary to drugs
0.571 0.429 0.000
H40.5 Glaucoma secondary to other eye disorders
0.571 0.429 0.000
H40.4 Glaucoma secondary to eye inflammation
0.571 0.429 0.000
H40.3 Glaucoma secondary to eye trauma
0.571 0.429 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.571 0.429 0.000
H35 Other retinal disorders
0.571 0.429 0.000
S69 Other and unspecified injuries of wrist and hand
0.570 0.430 0.000
S67 Crushing injury of wrist and hand
0.570 0.430 0.000
S65 Injury of blood vessels at wrist and hand level
0.570 0.430 0.000
S64 Injury of nerves at wrist and hand level
0.570 0.430 0.000
S60 Superficial injury of wrist and hand
0.570 0.430 0.000
C54.1 Endometrium
0.570 0.430 0.000
K50 Crohn's disease [regional enteritis]
0.569 0.431 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.566 0.433 0.000
H52.1 Myopia
0.566 0.434 0.000
K90.0 Coeliac disease
0.566 0.434 0.000
D46 Myelodysplastic syndromes
0.566 0.434 0.000
H60.1 Cellulitis of external ear
0.565 0.435 0.000
K14.0 Glossitis
0.565 0.435 0.000
S32 Fracture of lumbar spine and pelvis
0.565 0.435 0.000
S27 Injury of other and unspecified intrathoracic organs
0.565 0.435 0.000
K01 Embedded and impacted teeth
0.564 0.436 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.564 0.436 0.000
Q80-Q89 Other congenital malformations
0.564 0.436 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.564 0.436 0.000
Q60-Q64 Congenital malformations of the urinary system
0.564 0.436 0.000
Q50-Q56 Congenital malformations of genital organs
0.564 0.436 0.000
Q35-Q37 Cleft lip and cleft palate
0.564 0.436 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.564 0.436 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.564 0.436 0.000
Q00-Q07 Congenital malformations of the nervous system
0.564 0.436 0.000
B35-B49 Mycoses
0.564 0.436 0.000
L29 Pruritus
0.561 0.439 0.000
H61.0 Perichondritis of external ear
0.561 0.439 0.000
M20.5 Other deformities of toe(s) (acquired)
0.561 0.439 0.000
Chapter IX Diseases of the circulatory system
0.561 0.439 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.560 0.440 0.000
M25.9 Joint disorder, unspecified
0.559 0.441 0.000
M25.8 Other specified joint disorders
0.559 0.441 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.559 0.441 0.000
M25.3 Other instability of joint
0.559 0.441 0.000
M25.2 Flail joint
0.559 0.441 0.000
M25.1 Fistula of joint
0.559 0.441 0.000
M25.0 Haemarthrosis
0.559 0.441 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.559 0.441 0.000
E66.1 Drug-induced obesity
0.559 0.441 0.000
E66.0 Obesity due to excess calories
0.559 0.441 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.558 0.442 0.000
G62.9 Polyneuropathy, unspecified
0.558 0.442 0.000
Z47 Other orthopaedic follow-up care
0.557 0.443 0.000
K51.9 Ulcerative colitis, unspecified
0.557 0.443 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.556 0.443 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.556 0.444 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.556 0.444 0.000
M21.0 Valgus deformity, not elsewhere classified
0.556 0.444 0.000
C92 Myeloid leukaemia
0.555 0.445 0.000
S01.0 Open wound of scalp
0.555 0.445 0.000
H20 Iridocyclitis
0.554 0.445 0.000
S09 Other and unspecified injuries of head
0.554 0.446 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.554 0.446 0.000
H50.0 Convergent concomitant strabismus
0.554 0.446 0.000
L30 Other dermatitis
0.554 0.446 0.000
D45 Polycythaemia vera
0.554 0.446 0.000
H81 Disorders of vestibular function
0.553 0.447 0.000
G12 Spinal muscular atrophy and related syndromes
0.552 0.448 0.000
C77.1 Intrathoracic lymph nodes
0.552 0.448 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.550 0.449 0.000
E34 Other endocrine disorders
0.550 0.449 0.000
E32 Diseases of thymus
0.550 0.449 0.000
E31 Polyglandular dysfunction
0.550 0.449 0.000
E30 Disorders of puberty, not elsewhere classified
0.550 0.449 0.000
E29 Testicular dysfunction
0.550 0.449 0.000
E28 Ovarian dysfunction
0.550 0.449 0.000
E26 Hyperaldosteronism
0.550 0.449 0.000
E25 Adrenogenital disorders
0.550 0.449 0.000
E24 Cushing's syndrome
0.550 0.449 0.000
E23 Hypofunction and other disorders of pituitary gland
0.550 0.449 0.000
E22 Hyperfunction of pituitary gland
0.550 0.449 0.000
E20 Hypoparathyroidism
0.550 0.449 0.000
K04.7 Periapical abscess without sinus
0.550 0.450 0.000
E14.9 Without complications
0.550 0.450 0.000
C50 Malignant neoplasm of breast
0.549 0.451 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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