TreeWAS – Variant ID: rs1451488

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C20 Malignant neoplasm of rectum	0.938	0.062	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.924	0.076	0.000
C15-C26 Malignant neoplasms of digestive organs	0.919	0.081	0.000
C25 Malignant neoplasm of pancreas	0.862	0.138	0.000
C25.9 Pancreas, unspecified	0.802	0.198	0.000
C25.1 Body of pancreas	0.785	0.215	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.747	0.253	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.671	0.329	0.000
C25.4 Endocrine pancreas	0.668	0.332	0.000
C26.0 Intestinal tract, part unspecified	0.648	0.352	0.000
C23 Malignant neoplasm of gallbladder	0.619	0.381	0.000
C25.0 Head of pancreas	0.615	0.385	0.000
C25.2 Tail of pancreas	0.615	0.385	0.000
C17 Malignant neoplasm of small intestine	0.609	0.391	0.000
C21 Malignant neoplasm of anus and anal canal	0.591	0.409	0.000
C15 Malignant neoplasm of oesophagus	0.587	0.413	0.000
C25.8 Overlapping lesion of pancreas	0.578	0.422	0.000
C26.8 Overlapping lesion of digestive system	0.536	0.464	0.000
C26.1 Spleen	0.536	0.464	0.000
C25.3 Pancreatic duct	0.526	0.473	0.000
C17.9 Small intestine, unspecified	0.509	0.491	0.000
C24.0 Extrahepatic bile duct	0.508	0.492	0.000
C24.9 Biliary tract, unspecified	0.502	0.498	0.000
C26.9 Ill-defined sites within the digestive system	0.487	0.513	0.000
C24.8 Overlapping lesion of biliary tract	0.481	0.519	0.000
C25.7 Other parts of pancreas	0.472	0.528	0.000
C17.2 Ileum	0.463	0.536	0.000
C15.0 Cervical part of oesophagus	0.453	0.547	0.000
C24.1 Ampulla of Vater	0.438	0.562	0.000
C17.8 Overlapping lesion of small intestine	0.436	0.563	0.000
C17.3 Meckel's diverticulum	0.436	0.563	0.000
C15.4 Middle third of oesophagus	0.428	0.572	0.000
C21.2 Cloacogenic zone	0.424	0.576	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.423	0.577	0.000
C15.8 Overlapping lesion of oesophagus	0.421	0.579	0.000
C15.2 Abdominal part of oesophagus	0.421	0.579	0.000
C15.1 Thoracic part of oesophagus	0.414	0.586	0.000
C15.3 Upper third of oesophagus	0.411	0.589	0.000
C21.1 Anal canal	0.400	0.599	0.000
C21.0 Anus, unspecified	0.385	0.615	0.000
C15.9 Oesophagus, unspecified	0.382	0.618	0.000
C15.5 Lower third of oesophagus	0.364	0.636	0.000
C16 Malignant neoplasm of stomach	0.364	0.636	0.000
C17.1 Jejunum	0.357	0.643	0.000
C16.6 Greater curvature of stomach, unspecified	0.309	0.691	0.000
C17.0 Duodenum	0.298	0.702	0.000
C16.2 Body of stomach	0.274	0.726	0.000
C16.8 Overlapping lesion of stomach	0.265	0.734	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.259	0.741	0.000
C16.1 Fundus of stomach	0.253	0.747	0.000
C16.3 Pyloric antrum	0.235	0.765	0.000
C16.5 Lesser curvature of stomach, unspecified	0.233	0.767	0.000
C16.4 Pylorus	0.223	0.777	0.000
C22.7 Other specified carcinomas of liver	0.186	0.814	0.000
C22.4 Other sarcomas of liver	0.186	0.814	0.000
C22.3 Angiosarcoma of liver	0.186	0.814	0.000
C22.2 Hepatoblastoma	0.186	0.814	0.000
C16.0 Cardia	0.174	0.826	0.000
C16.9 Stomach, unspecified	0.157	0.843	0.000
C22.9 Liver, unspecified	0.154	0.846	0.000
C22.0 Liver cell carcinoma	0.107	0.893	0.000
C22.1 Intrahepatic bile duct carcinoma	0.101	0.899	0.000
C18 Malignant neoplasm of colon	0.084	0.916	0.000
C18.9 Colon, unspecified	0.071	0.929	0.000
C18.8 Overlapping lesion of colon	0.070	0.930	0.000
C18.7 Sigmoid colon	0.065	0.935	0.000
C18.4 Transverse colon	0.063	0.937	0.000
C62.9 Testis, unspecified	0.000	0.942	0.058
C61 Malignant neoplasm of prostate	0.000	0.947	0.053
C62 Malignant neoplasm of testis	0.000	0.947	0.053
C18.1 Appendix	0.052	0.948	0.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.952	0.048
C18.6 Descending colon	0.047	0.953	0.000
C62.1 Descended testis	0.000	0.959	0.041
R61.9 Hyperhidrosis, unspecified	0.040	0.960	0.000
C62.0 Undescended testis	0.000	0.962	0.038
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.965	0.034
C18.3 Hepatic flexure	0.029	0.971	0.000
C18.5 Splenic flexure	0.027	0.973	0.000
C63.9 Male genital organ, unspecified	0.000	0.975	0.025
C63.8 Overlapping lesion of male genital organs	0.000	0.975	0.025
C63.7 Other specified male genital organs	0.000	0.975	0.025
C63.1 Spermatic cord	0.000	0.975	0.025
C63.0 Epididymis	0.000	0.975	0.025
C63.2 Scrotum	0.000	0.975	0.024
R06.0 Dyspnoea	0.023	0.977	0.000
C60 Malignant neoplasm of penis	0.001	0.979	0.020
C18.0 Caecum	0.019	0.981	0.000
R61 Hyperhidrosis	0.018	0.982	0.000
C60.8 Overlapping lesion of penis	0.001	0.985	0.015
C60.2 Body of penis	0.001	0.985	0.015
C60.0 Prepuce	0.001	0.986	0.013
M41.99 Scoliosis, unspecified (Site unspecified)	0.014	0.986	0.000
R61.1 Generalised hyperhidrosis	0.013	0.986	0.000
K22.7 Barrett's oesophagus	0.013	0.987	0.000
R61.0 Localised hyperhidrosis	0.013	0.987	0.000
C60.1 Glans penis	0.001	0.987	0.012
R06.4 Hyperventilation	0.012	0.988	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.012	0.988	0.000
M41.9 Scoliosis, unspecified	0.012	0.988	0.000
I42.0 Dilated cardiomyopathy	0.000	0.988	0.012
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.011	0.989	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.011	0.989	0.000
R06 Abnormalities of breathing	0.011	0.989	0.000
Q43.0 Meckel's diverticulum	0.011	0.989	0.000
E16.2 Hypoglycaemia, unspecified	0.010	0.990	0.000
C60.9 Penis, unspecified	0.001	0.990	0.009
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.009	0.991	0.000
E55.9 Vitamin D deficiency, unspecified	0.009	0.991	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.009	0.991	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.009	0.991	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.009	0.991	0.000
R06.6 Hiccough	0.009	0.991	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.009	0.991	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.009	0.991	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.009	0.991	0.000
R06.1 Stridor	0.009	0.991	0.000
R06.7 Sneezing	0.008	0.992	0.000
R06.3 Periodic breathing	0.008	0.992	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.008	0.992	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.008	0.992	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.008	0.992	0.000
C18.2 Ascending colon	0.007	0.992	0.001
B17.1 Acute hepatitis C	0.000	0.993	0.007
Q43 Other congenital malformations of intestine	0.007	0.993	0.000
I42.8 Other cardiomyopathies	0.000	0.993	0.007
R06.2 Wheezing	0.007	0.993	0.000
I42 Cardiomyopathy	0.000	0.993	0.007
Q43.3 Congenital malformations of intestinal fixation	0.007	0.993	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.993	0.007
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.006	0.994	0.000
T82.3 Mechanical complication of other vascular grafts	0.006	0.994	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.006	0.994	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.994	0.006
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.994	0.006
T82.0 Mechanical complication of heart valve prosthesis	0.006	0.994	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.994	0.006
Z93.1 Gastrostomy status	0.006	0.994	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.006	0.994	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.006	0.994	0.000
B17 Other acute viral hepatitis	0.000	0.994	0.006
M41 Scoliosis	0.006	0.994	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.995	0.005
Q43.7 Persistent cloaca	0.005	0.995	0.000
Q43.6 Congenital fistula of rectum and anus	0.005	0.995	0.000
Q43.5 Ectopic anus	0.005	0.995	0.000
Q43.4 Duplication of intestine	0.005	0.995	0.000
Q43.2 Other congenital functional disorders of colon	0.005	0.995	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.995	0.005
H92.1 Otorrhoea	0.005	0.995	0.000
Q43.8 Other specified congenital malformations of intestine	0.005	0.995	0.000
E55 Vitamin D deficiency	0.005	0.995	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.995	0.005
I42.5 Other restrictive cardiomyopathy	0.000	0.995	0.005
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.995	0.005
Q43.1 Hirschsprung's disease	0.005	0.995	0.000
E16 Other disorders of pancreatic internal secretion	0.005	0.995	0.000
B18 Chronic viral hepatitis	0.000	0.995	0.005
Z93.3 Colostomy status	0.005	0.995	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.995	0.005
Z93.2 Ileostomy status	0.005	0.995	0.000
B17.8 Other specified acute viral hepatitis	0.000	0.995	0.005
D35.0 Adrenal gland	0.000	0.995	0.005
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.995	0.005
B17.2 Acute hepatitis E	0.000	0.996	0.004
M41.5 Other secondary scoliosis	0.004	0.996	0.000
K91.4 Colostomy and enterostomy malfunction	0.004	0.996	0.000
B15-B19 Viral hepatitis	0.000	0.996	0.004
I42.4 Endocardial fibroelastosis	0.000	0.996	0.004
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.996	0.004
M41.3 Thoracogenic scoliosis	0.004	0.996	0.000
M41.2 Other idiopathic scoliosis	0.004	0.996	0.000
M41.1 Juvenile idiopathic scoliosis	0.004	0.996	0.000
M41.0 Infantile idiopathic scoliosis	0.004	0.996	0.000
M41.4 Neuromuscular scoliosis	0.004	0.996	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.996	0.004
Q76.0 Spina bifida occulta	0.004	0.996	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.996	0.004
B17.9 Acute viral hepatitis, unspecified	0.000	0.996	0.004
Z93 Artificial opening status	0.004	0.996	0.000
M41.8 Other forms of scoliosis	0.004	0.996	0.000
E55.0 Rickets, active	0.004	0.996	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.996	0.004
S61.8 Open wound of other parts of wrist and hand	0.000	0.996	0.004
E16.1 Other hypoglycaemia	0.004	0.996	0.000
S70.0 Contusion of hip	0.004	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.996	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.996	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.996	0.000
E16.3 Increased secretion of glucagon	0.004	0.996	0.000
B18.8 Other chronic viral hepatitis	0.000	0.996	0.004
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.996	0.004
T86.1 Kidney transplant failure and rejection	0.004	0.996	0.000
B18.2 Chronic viral hepatitis C	0.000	0.996	0.004
B16 Acute hepatitis B	0.000	0.996	0.004
B18.9 Chronic viral hepatitis, unspecified	0.000	0.996	0.003
I42.6 Alcoholic cardiomyopathy	0.000	0.996	0.003
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.996	0.004
K09.2 Other cysts of jaw	0.000	0.996	0.004
M41.56 Other secondary scoliosis (Lumbar region)	0.003	0.996	0.000
S46.3 Injury of muscle and tendon of triceps	0.000	0.996	0.003
M41.59 Other secondary scoliosis (Site unspecified)	0.003	0.997	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.003	0.997	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.003	0.997	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.003	0.997	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.003	0.997	0.000
O62.2 Other uterine inertia	0.003	0.997	0.000
B19 Unspecified viral hepatitis	0.000	0.997	0.003
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.003	0.997	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.003	0.997	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.003	0.997	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.003	0.997	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.003	0.997	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.003	0.997	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.003	0.997	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.003	0.997	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.003	0.997	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.003	0.997	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.003	0.997	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.003	0.997	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.003	0.997	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.003	0.997	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.003	0.997	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.003	0.997	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.003	0.997	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.003	0.997	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.003	0.997	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.003	0.997	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.003	0.997	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.003	0.997	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.003	0.997	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.003	0.997	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.003	0.997	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.003	0.997	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.003	0.997	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.003	0.997	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.003	0.997	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.003	0.997	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.003	0.997	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.003	0.997	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.997	0.003
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.997	0.003
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.997	0.003
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.997	0.003
S70.1 Contusion of thigh	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.003	0.997	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.003	0.997	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.003	0.997	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.003	0.997	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.003	0.997	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.003	0.997	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.003	0.997	0.000
F50.0 Anorexia nervosa	0.003	0.997	0.000
R06.8 Other and unspecified abnormalities of breathing	0.003	0.997	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.997	0.003
D34 Benign neoplasm of thyroid gland	0.000	0.997	0.003
F50.9 Eating disorder, unspecified	0.003	0.997	0.000
Z93.9 Artificial opening status, unspecified	0.003	0.997	0.000
Z93.6 Other artificial openings of urinary tract status	0.003	0.997	0.000
F50 Eating disorders	0.003	0.997	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.997	0.003
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.997	0.003
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.997	0.003
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.003	0.997	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.003	0.997	0.000
B15 Acute hepatitis A	0.000	0.997	0.003
Z93.8 Other artificial opening status	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.997	0.003
M24.07 Loose body in joint (Ankle and foot)	0.000	0.997	0.003
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
S70.8 Other superficial injuries of hip and thigh	0.003	0.997	0.000
O62.1 Secondary uterine inertia	0.003	0.997	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.997	0.002
F50.2 Bulimia nervosa	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.000	0.997	0.003
D59 Acquired haemolytic anaemia	0.000	0.997	0.003
S62.60 Fracture of other finger (closed)	0.003	0.997	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.997	0.003
B19.9 Unspecified viral hepatitis without coma	0.000	0.997	0.002
F52.2 Failure of genital response	0.003	0.997	0.000
Z04.1 Examination and observation following transport accident	0.003	0.997	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.003	0.997	0.000
O62 Abnormalities of forces of labour	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
G12.2 Motor neuron disease	0.000	0.998	0.002
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
F50.8 Other eating disorders	0.002	0.998	0.000
F50.5 Vomiting associated with other psychological disturbances	0.002	0.998	0.000
F50.4 Overeating associated with other psychological disturbances	0.002	0.998	0.000
F50.3 Atypical bulimia nervosa	0.002	0.998	0.000
F50.1 Atypical anorexia nervosa	0.002	0.998	0.000
M48.0 Spinal stenosis	0.000	0.998	0.002
Z93.4 Other artificial openings of gastro-intestinal tract status	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
B15.0 Hepatitis A with hepatic coma	0.000	0.998	0.002
I45.9 Conduction disorder, unspecified	0.000	0.998	0.002
K09 Cysts of oral region, not elsewhere classified	0.000	0.998	0.002
O62.3 Precipitate labour	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.998	0.002
G55.0 Nerve root and plexus compressions in neoplastic disease	0.002	0.998	0.000
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.998	0.002
D59.8 Other acquired haemolytic anaemias	0.000	0.998	0.002
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.998	0.002
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.002
D59.3 Haemolytic-uraemic syndrome	0.000	0.998	0.002
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.998	0.002
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
K09.9 Cyst of oral region, unspecified	0.000	0.998	0.002
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.998	0.002
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.998	0.002
T82.1 Mechanical complication of cardiac electronic device	0.002	0.998	0.000
K91.1 Postgastric surgery syndromes	0.002	0.998	0.000
C04.9 Floor of mouth, unspecified	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
G44.2 Tension-type headache	0.000	0.998	0.002
M24.0 Loose body in joint	0.000	0.998	0.002
O62.0 Primary inadequate contractions	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.002
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
J67 Hypersensitivity pneumonitis due to organic dust	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.000	0.998	0.002
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
D11.9 Major salivary gland, unspecified	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.000	0.998	0.002
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.002
E63 Other nutritional deficiencies	0.002	0.998	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.998	0.000
Y83.0 Surgical operation with transplant of whole organ	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
Z93.0 Tracheostomy status	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.998	0.002
S49.7 Multiple injuries of shoulder and upper arm	0.000	0.998	0.002
H00.1 Chalazion	0.000	0.998	0.002
L73.8 Other specified follicular disorders	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.002	0.998	0.000
Z51.8 Other specified medical care	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.002
B15.9 Hepatitis A without hepatic coma	0.000	0.998	0.001
C79.2 Secondary malignant neoplasm of skin	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.000	0.998	0.002
M24.08 Loose body in joint (Other)	0.000	0.998	0.002
M24.00 Loose body in joint (Multiple sites)	0.000	0.998	0.002
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
H92.2 Otorrhagia	0.002	0.998	0.000
I84.8 Unspecified haemorrhoids with other complications	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
C02.8 Overlapping lesion of tongue	0.002	0.998	0.000
E54 Ascorbic acid deficiency	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.002	0.998	0.000
J67.7 Air-conditioner and humidifier lung	0.002	0.998	0.000
J67.6 Maple-bark-stripper's lung	0.002	0.998	0.000
J67.5 Mushroom-worker's lung	0.002	0.998	0.000
J67.4 Maltworker's lung	0.002	0.998	0.000
J67.3 Suberosis	0.002	0.998	0.000
J67.1 Bagassosis	0.002	0.998	0.000
J67.0 Farmer's lung	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
E51 Thiamine deficiency	0.002	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.000	0.998	0.002
G25.0 Essential tremor	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.002	0.998	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.001	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.001	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.001	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.002	0.998	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.998	0.002
S40-S49 Injuries to the shoulder and upper arm	0.000	0.998	0.002
C04.0 Anterior floor of mouth	0.002	0.998	0.000
E61.2 Magnesium deficiency	0.002	0.998	0.000
O81.0 Low forceps delivery	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.001	0.998	0.000
E53.1 Pyridoxine deficiency	0.001	0.998	0.000
E53.0 Riboflavin deficiency	0.001	0.998	0.000
Z93.5 Cystostomy status	0.001	0.998	0.000
C04 Malignant neoplasm of floor of mouth	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.001	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.001	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.001	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.001	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.001	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.001	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.001	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.001	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.001	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.001	0.998	0.000
E64.3 Sequelae of rickets	0.001	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.001	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.001	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.001	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.001	0.998	0.000
F55 Abuse of non-dependence-producing substances	0.001	0.998	0.000
C67.4 Posterior wall of bladder	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.001	0.998	0.000
E56.8 Deficiency of other vitamins	0.001	0.998	0.000
E56.0 Deficiency of vitamin E	0.001	0.998	0.000
J67.2 Bird fancier's lung	0.001	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
H00 Hordeolum and chalazion	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.001	0.998	0.000
E56.1 Deficiency of vitamin K	0.001	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
K13.0 Diseases of lips	0.000	0.998	0.002
Q45 Other congenital malformations of digestive system	0.001	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.001	0.998	0.000
C67.5 Bladder neck	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations