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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1459148
log Bayes Factor = 10.3063
Chromosome 14   position 98,840,443  (GRCh37) Explore rs1459148 on Ensembl!
Variant rs1459148 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.997 0.003 0.000
M06 Other rheumatoid arthritis
0.996 0.004 0.000
M15-M19 Arthrosis
0.996 0.004 0.000
M17.9 Gonarthrosis, unspecified
0.995 0.005 0.000
M17 Gonarthrosis [arthrosis of knee]
0.995 0.005 0.000
M06.9 Rheumatoid arthritis, unspecified
0.995 0.005 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.993 0.007 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.989 0.011 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.985 0.015 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.981 0.019 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.979 0.021 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.977 0.023 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.975 0.025 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.975 0.025 0.000
E00-E07 Disorders of thyroid gland
0.972 0.028 0.000
R29.6 Tendency to fall, not elsewhere classified
0.971 0.029 0.000
S80-S89 Injuries to the knee and lower leg
0.961 0.039 0.000
S00-S09 Injuries to the head
0.957 0.043 0.000
Chapter XIV Diseases of the genitourinary system
0.956 0.044 0.000
L20-L30 Dermatitis and eczema
0.951 0.049 0.000
F10.2 Dependence syndrome
0.944 0.056 0.000
Chapter VII Diseases of the eye and adnexa
0.944 0.056 0.000
N20-N23 Urolithiasis
0.932 0.068 0.000
M45-M49 Spondylopathies
0.932 0.068 0.000
S01 Open wound of head
0.931 0.069 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.931 0.069 0.000
F10.3 Withdrawal state
0.925 0.075 0.000
M65-M68 Disorders of synovium and tendon
0.923 0.077 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.918 0.082 0.000
L30 Other dermatitis
0.918 0.082 0.000
N40-N51 Diseases of male genital organs
0.915 0.085 0.000
M79.8 Other specified soft tissue disorders
0.913 0.087 0.000
S20-S29 Injuries to the thorax
0.911 0.089 0.000
E04 Other non-toxic goitre
0.903 0.097 0.000
T66-T78 Other and unspecified effects of external causes
0.900 0.100 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.899 0.101 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.895 0.105 0.000
L30.9 Dermatitis, unspecified
0.894 0.106 0.000
R26 Abnormalities of gait and mobility
0.894 0.106 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.893 0.107 0.000
N40 Hyperplasia of prostate
0.892 0.108 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.891 0.109 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.884 0.116 0.000
M45 Ankylosing spondylitis
0.880 0.120 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.880 0.120 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.878 0.122 0.000
M65 Synovitis and tenosynovitis
0.877 0.123 0.000
N20 Calculus of kidney and ureter
0.877 0.123 0.000
N10-N16 Renal tubulo-interstitial diseases
0.872 0.128 0.000
S83.2 Tear of meniscus, current
0.871 0.129 0.000
F10.1 Harmful use
0.868 0.132 0.000
R25 Abnormal involuntary movements
0.867 0.133 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.862 0.138 0.000
M72 Fibroblastic disorders
0.860 0.140 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.859 0.141 0.000
H43-H45 Disorders of vitreous body and globe
0.857 0.143 0.000
M06.4 Inflammatory polyarthropathy
0.854 0.146 0.000
R94 Abnormal results of function studies
0.852 0.148 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.851 0.149 0.000
R47-R49 Symptoms and signs involving speech and voice
0.847 0.153 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.846 0.154 0.000
E04.9 Non-toxic goitre, unspecified
0.846 0.154 0.000
M80-M85 Disorders of bone density and structure
0.844 0.156 0.000
N23 Unspecified renal colic
0.844 0.156 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.835 0.165 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.833 0.167 0.000
H18 Other disorders of cornea
0.833 0.167 0.000
N13 Obstructive and reflux uropathy
0.832 0.168 0.000
R94.5 Abnormal results of liver function studies
0.829 0.171 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.829 0.171 0.000
E05.9 Thyrotoxicosis, unspecified
0.828 0.172 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.825 0.175 0.000
D70 Agranulocytosis
0.823 0.177 0.000
M79.6 Pain in limb
0.823 0.177 0.000
M48 Other spondylopathies
0.821 0.179 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.819 0.181 0.000
T78 Adverse effects, not elsewhere classified
0.818 0.182 0.000
S40-S49 Injuries to the shoulder and upper arm
0.816 0.183 0.000
R23 Other skin changes
0.816 0.184 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.815 0.185 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.815 0.185 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.813 0.187 0.000
S01.1 Open wound of eyelid and periocular area
0.810 0.190 0.000
L40-L45 Papulosquamous disorders
0.810 0.190 0.000
S01.8 Open wound of other parts of head
0.810 0.190 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.809 0.191 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.809 0.191 0.000
M79.66 Pain in limb (Lower leg)
0.801 0.199 0.000
Chapter XX External causes of morbidity and mortality
0.801 0.199 0.000
M71 Other bursopathies
0.799 0.201 0.000
M79.1 Myalgia
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.797 0.203 0.000
N13.3 Other and unspecified hydronephrosis
0.796 0.204 0.000
M91-M94 Chondropathies
0.793 0.207 0.000
H43 Disorders of vitreous body
0.793 0.207 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.790 0.210 0.000
M86-M90 Other osteopathies
0.788 0.212 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.788 0.212 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.787 0.213 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.786 0.214 0.000
F11 Mental and behavioural disorders due to use of opioids
0.785 0.215 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.783 0.217 0.000
R76 Other abnormal immunological findings in serum
0.782 0.218 0.000
N73 Other female pelvic inflammatory diseases
0.780 0.220 0.000
N20.2 Calculus of kidney with calculus of ureter
0.778 0.222 0.000
M79.2 Neuralgia and neuritis, unspecified
0.777 0.223 0.000
L50-L54 Urticaria and erythema
0.777 0.223 0.000
N20.1 Calculus of ureter
0.775 0.225 0.000
F10.4 Withdrawal state with delirium
0.773 0.227 0.000
E06 Thyroiditis
0.773 0.227 0.000
M17.1 Other primary gonarthrosis
0.772 0.228 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.770 0.230 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.769 0.231 0.000
S27 Injury of other and unspecified intrathoracic organs
0.769 0.231 0.000
R27 Other lack of coordination
0.767 0.233 0.000
S81 Open wound of lower leg
0.765 0.234 0.000
R47 Speech disturbances, not elsewhere classified
0.765 0.235 0.000
L91 Hypertrophic disorders of skin
0.765 0.235 0.000
H40-H42 Glaucoma
0.764 0.236 0.000
Chapter XXII Codes for special purposes
0.761 0.239 0.000
H25-H28 Disorders of lens
0.758 0.242 0.000
S00 Superficial injury of head
0.756 0.243 0.000
S01.5 Open wound of lip and oral cavity
0.756 0.244 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.753 0.247 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.753 0.247 0.000
N73.6 Female pelvic peritoneal adhesions
0.752 0.248 0.000
M77 Other enthesopathies
0.752 0.248 0.000
S01.2 Open wound of nose
0.751 0.249 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.746 0.254 0.000
S89 Other and unspecified injuries of lower leg
0.744 0.256 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.743 0.257 0.000
S80 Superficial injury of lower leg
0.742 0.258 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.741 0.259 0.000
M75 Shoulder lesions
0.741 0.259 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.740 0.259 0.000
E07 Other disorders of thyroid
0.739 0.261 0.000
M18 Arthrosis of first carpometacarpal joint
0.738 0.262 0.000
N45 Orchitis and epididymitis
0.737 0.263 0.000
E40-E46 Malnutrition
0.736 0.264 0.000
H20 Iridocyclitis
0.736 0.264 0.000
M07 Psoriatic and enteropathic arthropathies
0.735 0.265 0.000
M79.5 Residual foreign body in soft tissue
0.735 0.265 0.000
M79.0 Rheumatism, unspecified
0.735 0.265 0.000
E03 Other hypothyroidism
0.734 0.266 0.000
M20-M25 Other joint disorders
0.734 0.266 0.000
E04.2 Non-toxic multinodular goitre
0.733 0.267 0.000
N99-N99 Other disorders of the genitourinary system
0.733 0.267 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.732 0.268 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.731 0.268 0.000
R25.1 Tremor, unspecified
0.731 0.269 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.730 0.270 0.000
L27 Dermatitis due to substances taken internally
0.730 0.270 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.728 0.272 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.726 0.273 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.726 0.274 0.000
M11 Other crystal arthropathies
0.725 0.275 0.000
S01.3 Open wound of ear
0.723 0.277 0.000
M84 Disorders of continuity of bone
0.722 0.278 0.000
R71 Abnormality of red blood cells
0.721 0.279 0.000
S02 Fracture of skull and facial bones
0.720 0.280 0.000
S20 Superficial injury of thorax
0.719 0.281 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
D75 Other diseases of blood and blood-forming organs
0.717 0.283 0.000
T78.2 Anaphylactic shock, unspecified
0.716 0.283 0.000
N48 Other disorders of penis
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.715 0.285 0.000
M12 Other specific arthropathies
0.715 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M08 Juvenile arthritis
0.715 0.285 0.000
M06.8 Other specified rheumatoid arthritis
0.714 0.286 0.000
M06.3 Rheumatoid nodule
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.714 0.286 0.000
M06.1 Adult-onset Still's disease
0.714 0.286 0.000
M15 Polyarthrosis
0.714 0.286 0.000
M17.5 Other secondary gonarthrosis
0.714 0.286 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.714 0.286 0.000
M17.3 Other posttraumatic gonarthrosis
0.714 0.286 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.714 0.286 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.713 0.286 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.713 0.286 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.713 0.286 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.713 0.286 0.000
R29.4 Clicking hip
0.713 0.287 0.000
R29.3 Abnormal posture
0.713 0.287 0.000
R29.2 Abnormal reflex
0.713 0.287 0.000
R29.1 Meningismus
0.713 0.287 0.000
R29.0 Tetany
0.713 0.287 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.713 0.287 0.000
M40-M43 Deforming dorsopathies
0.713 0.287 0.000
E70-E90 Metabolic disorders
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.712 0.288 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.712 0.288 0.000
N13.6 Pyonephrosis
0.710 0.290 0.000
H18.5 Hereditary corneal dystrophies
0.709 0.291 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
R76.8 Other specified abnormal immunological findings in serum
0.708 0.292 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
H16 Keratitis
0.706 0.294 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.706 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.295 0.000
F80-F89 Disorders of psychological development
0.705 0.295 0.000
F70-F79 Mental retardation
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
N41 Inflammatory diseases of prostate
0.704 0.295 0.000
L81 Other disorders of pigmentation
0.703 0.297 0.000
S42 Fracture of shoulder and upper arm
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.298 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.298 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.298 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.298 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.298 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.298 0.000
M66 Spontaneous rupture of synovium and tendon
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
F10.9 Unspecified mental and behavioural disorder
0.700 0.300 0.000
F10.8 Other mental and behavioural disorders
0.700 0.300 0.000
F10.7 Residual and late-onset psychotic disorder
0.700 0.300 0.000
F10.6 Amnesic syndrome
0.700 0.300 0.000
F10.5 Psychotic disorder
0.700 0.300 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.700 0.300 0.000
M79.9 Soft tissue disorder, unspecified
0.699 0.301 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.699 0.301 0.000
M79.3 Panniculitis, unspecified
0.699 0.301 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.698 0.302 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.697 0.303 0.000
E00 Congenital iodine-deficiency syndrome
0.697 0.303 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.697 0.303 0.000
E16 Other disorders of pancreatic internal secretion
0.696 0.303 0.000
H43.1 Vitreous haemorrhage
0.696 0.304 0.000
S90-S99 Injuries to the ankle and foot
0.695 0.305 0.000
R26.3 Immobility
0.695 0.305 0.000
S29 Other and unspecified injuries of thorax
0.694 0.306 0.000
Q60-Q64 Congenital malformations of the urinary system
0.694 0.306 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.693 0.307 0.000
L29 Pruritus
0.692 0.307 0.000
R47.1 Dysarthria and anarthria
0.691 0.309 0.000
M48.0 Spinal stenosis
0.691 0.309 0.000
Q00-Q07 Congenital malformations of the nervous system
0.691 0.309 0.000
T14 Injury of unspecified body region
0.690 0.310 0.000
H18.8 Other specified disorders of cornea
0.689 0.311 0.000
S88 Traumatic amputation of lower leg
0.689 0.311 0.000
S87 Crushing injury of lower leg
0.689 0.311 0.000
S86 Injury of muscle and tendon at lower leg level
0.689 0.311 0.000
S85 Injury of blood vessels at lower leg level
0.689 0.311 0.000
S84 Injury of nerves at lower leg level
0.689 0.311 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.688 0.312 0.000
H55-H59 Other disorders of eye and adnexa
0.688 0.312 0.000
M85 Other disorders of bone density and structure
0.687 0.313 0.000
S08 Traumatic amputation of part of head
0.686 0.314 0.000
S07 Crushing injury of head
0.686 0.314 0.000
S05 Injury of eye and orbit
0.686 0.314 0.000
S04 Injury of cranial nerves
0.686 0.314 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.686 0.314 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.686 0.314 0.000
W00-W19 Falls
0.686 0.314 0.000
S32 Fracture of lumbar spine and pelvis
0.685 0.315 0.000
H18.6 Keratoconus
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.316 0.000
F10.0 Acute intoxication
0.683 0.317 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.683 0.317 0.000
L03 Cellulitis
0.683 0.317 0.000
R23.4 Changes in skin texture
0.682 0.318 0.000
L25 Unspecified contact dermatitis
0.682 0.318 0.000
L24 Irritant contact dermatitis
0.682 0.318 0.000
L23 Allergic contact dermatitis
0.682 0.318 0.000
L21 Seborrhoeic dermatitis
0.682 0.318 0.000
L20 Atopic dermatitis
0.682 0.318 0.000
L26 Exfoliative dermatitis
0.682 0.318 0.000
L22 Diaper [napkin] dermatitis
0.682 0.318 0.000
T68 Hypothermia
0.681 0.319 0.000
T91 Sequelae of injuries of neck and trunk
0.681 0.319 0.000
S01.9 Open wound of head, part unspecified
0.681 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.680 0.320 0.000
M79.7 Fibromyalgia
0.680 0.320 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.679 0.321 0.000
M10 Gout
0.679 0.321 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.678 0.321 0.000
L28 Lichen simplex chronicus and prurigo
0.678 0.322 0.000
D72 Other disorders of white blood cells
0.678 0.322 0.000
N21 Calculus of lower urinary tract
0.677 0.323 0.000
M05 Seropositive rheumatoid arthritis
0.677 0.323 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.674 0.326 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.674 0.326 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.674 0.326 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.673 0.327 0.000
L43 Lichen planus
0.673 0.327 0.000
M46 Other inflammatory spondylopathies
0.672 0.328 0.000
F99-F99 Unspecified mental disorder
0.672 0.328 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.672 0.328 0.000
M79.19 Myalgia (Site unspecified)
0.671 0.329 0.000
E20-E35 Disorders of other endocrine glands
0.670 0.330 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.670 0.330 0.000
E50-E64 Other nutritional deficiencies
0.670 0.330 0.000
L91.8 Other hypertrophic disorders of skin
0.669 0.331 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.669 0.331 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.668 0.332 0.000
M49 Spondylopathies in diseases classified elsewhere
0.668 0.332 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.668 0.332 0.000
S01.7 Multiple open wounds of head
0.667 0.333 0.000
S01.4 Open wound of cheek and temporomandibular area
0.667 0.333 0.000
S83.7 Injury to multiple structures of knee
0.667 0.333 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.667 0.333 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.667 0.333 0.000
S83.3 Tear of articular cartilage of knee, current
0.667 0.333 0.000
S83.1 Dislocation of knee
0.667 0.333 0.000
S83.0 Dislocation of patella
0.667 0.333 0.000
S27.0 Traumatic pneumothorax
0.666 0.334 0.000
T93 Sequelae of injuries of lower limb
0.666 0.334 0.000
M06.0 Seronegative rheumatoid arthritis
0.665 0.335 0.000
S01.0 Open wound of scalp
0.665 0.335 0.000
R25.3 Fasciculation
0.664 0.336 0.000
H43.2 Crystalline deposits in vitreous body
0.664 0.336 0.000
T86 Failure and rejection of transplanted organs and tissues
0.663 0.337 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.662 0.338 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.661 0.339 0.000
T78.3 Angioneurotic oedema
0.661 0.339 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.661 0.339 0.000
H43.8 Other disorders of vitreous body
0.660 0.340 0.000
E05.8 Other thyrotoxicosis
0.658 0.342 0.000
E05.5 Thyroid crisis or storm
0.658 0.342 0.000
E05.4 Thyrotoxicosis factitia
0.658 0.342 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.658 0.342 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.658 0.342 0.000
L30.8 Other specified dermatitis
0.658 0.342 0.000
L30.5 Pityriasis alba
0.658 0.342 0.000
L30.4 Erythema intertrigo
0.658 0.342 0.000
L30.3 Infective dermatitis
0.658 0.342 0.000
L30.2 Cutaneous autosensitisation
0.658 0.342 0.000
L30.1 Dyshidrosis [pompholyx]
0.658 0.342 0.000
L30.0 Nummular dermatitis
0.658 0.342 0.000
M65.3 Trigger finger
0.658 0.342 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.657 0.343 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.656 0.344 0.000
N46 Male infertility
0.656 0.344 0.000
N44 Torsion of testis
0.656 0.344 0.000
L83 Acanthosis nigricans
0.656 0.344 0.000
M79.88 Other specified soft tissue disorders (Other)
0.654 0.346 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.654 0.346 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.654 0.346 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.654 0.346 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.654 0.346 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.654 0.346 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.654 0.346 0.000
L53 Other erythematous conditions
0.654 0.346 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.653 0.346 0.000
S26 Injury of heart
0.653 0.346 0.000
S25 Injury of blood vessels of thorax
0.653 0.346 0.000
S24 Injury of nerves and spinal cord at thorax level
0.653 0.346 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.653 0.346 0.000
S21 Open wound of thorax
0.653 0.346 0.000
S70 Superficial injury of hip and thigh
0.652 0.348 0.000
H25 Senile cataract
0.652 0.348 0.000
M75.1 Rotator cuff syndrome
0.650 0.350 0.000
R23.2 Flushing
0.649 0.351 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.648 0.352 0.000
F30-F39 Mood [affective] disorders
0.648 0.352 0.000
E04.8 Other specified non-toxic goitre
0.648 0.352 0.000
E04.0 Non-toxic diffuse goitre
0.648 0.352 0.000
R23.3 Spontaneous ecchymoses
0.647 0.353 0.000
F11.2 Dependence syndrome
0.646 0.354 0.000
T75 Effects of other external causes
0.646 0.354 0.000
T74 Maltreatment syndromes
0.646 0.354 0.000
T73 Effects of other deprivation
0.646 0.354 0.000
T70 Effects of air pressure and water pressure
0.646 0.354 0.000
T69 Other effects of reduced temperature
0.646 0.354 0.000
T67 Effects of heat and light
0.646 0.354 0.000
T71 Asphyxiation
0.646 0.354 0.000
T66 Unspecified effects of radiation
0.646 0.354 0.000
M94 Other disorders of cartilage
0.645 0.355 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.644 0.356 0.000
H21 Other disorders of iris and ciliary body
0.644 0.356 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.644 0.356 0.000
H17 Corneal scars and opacities
0.644 0.356 0.000
H15 Disorders of sclera
0.644 0.356 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.644 0.356 0.000
F12.1 Harmful use
0.643 0.357 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.643 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.641 0.358 0.000
N25-N29 Other disorders of kidney and ureter
0.641 0.359 0.000
R26.1 Paralytic gait
0.641 0.359 0.000
R26.0 Ataxic gait
0.641 0.359 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.641 0.359 0.000
E78.0 Pure hypercholesterolaemia
0.640 0.360 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.639 0.361 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.639 0.361 0.000
R70.0 Elevated erythrocyte sedimentation rate
0.638 0.362 0.000
N20.0 Calculus of kidney
0.638 0.362 0.000
R23.8 Other and unspecified skin changes
0.638 0.362 0.000
M22 Disorders of patella
0.638 0.362 0.000
N13.8 Other obstructive and reflux uropathy
0.636 0.364 0.000
H40 Glaucoma
0.636 0.364 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.636 0.364 0.000
H10-H13 Disorders of conjunctiva
0.635 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.635 0.365 0.000
R20 Disturbances of skin sensation
0.634 0.366 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.634 0.366 0.000
R77 Other abnormalities of plasma proteins
0.634 0.366 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.634 0.366 0.000
S22.3 Fracture of rib
0.632 0.368 0.000
H53-H54 Visual disturbances and blindness
0.631 0.368 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.631 0.369 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.631 0.369 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.631 0.369 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.631 0.369 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.631 0.369 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.631 0.369 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.631 0.369 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.631 0.369 0.000
E06.3 Autoimmune thyroiditis
0.630 0.370 0.000
N41.0 Acute prostatitis
0.629 0.371 0.000
M65.8 Other synovitis and tenosynovitis
0.629 0.371 0.000
M65.2 Calcific tendinitis
0.629 0.371 0.000
M65.1 Other infective (teno)synovitis
0.629 0.371 0.000
M65.0 Abscess of tendon sheath
0.629 0.371 0.000
N20.9 Urinary calculus, unspecified
0.629 0.371 0.000
N42 Other disorders of prostate
0.628 0.372 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.628 0.372 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.628 0.372 0.000
R74 Abnormal serum enzyme levels
0.627 0.373 0.000
M86 Osteomyelitis
0.627 0.373 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.625 0.374 0.000
N15 Other renal tubulo-interstitial diseases
0.625 0.374 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.625 0.374 0.000
N11 Chronic tubulo-interstitial nephritis
0.625 0.374 0.000
N10 Acute tubulo-interstitial nephritis
0.625 0.374 0.000
L91.0 Keloid scar
0.625 0.375 0.000
S00.1 Contusion of eyelid and periocular area
0.625 0.375 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.622 0.378 0.000
R25.0 Abnormal head movements
0.622 0.378 0.000
M31 Other necrotising vasculopathies
0.622 0.378 0.000
H44 Disorders of globe
0.621 0.379 0.000
L85 Other epidermal thickening
0.621 0.379 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.620 0.380 0.000
Q80-Q89 Other congenital malformations
0.620 0.380 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.620 0.380 0.000
Q35-Q37 Cleft lip and cleft palate
0.620 0.380 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.620 0.380 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.620 0.380 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.620 0.380 0.000
L89 Decubitus ulcer
0.620 0.380 0.000
H20.9 Iridocyclitis, unspecified
0.619 0.381 0.000
T87 Complications peculiar to reattachment and amputation
0.618 0.382 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.617 0.382 0.000
M72.9 Fibroblastic disorder, unspecified
0.617 0.383 0.000
M72.8 Other fibroblastic disorders
0.617 0.383 0.000
M72.6 Necrotizing fasciitis
0.617 0.383 0.000
M72.5 Fasciitis, not elsewhere classified
0.617 0.383 0.000
M72.4 Pseudosarcomatous fibromatosis
0.617 0.383 0.000
M72.3 Nodular fasciitis
0.617 0.383 0.000
M72.1 Knuckle pads
0.617 0.383 0.000
D55-D59 Haemolytic anaemias
0.616 0.384 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.616 0.384 0.000
R25.2 Cramp and spasm
0.615 0.385 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.614 0.386 0.000
L60-L75 Disorders of skin appendages
0.613 0.387 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.613 0.387 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.613 0.387 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.613 0.387 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.613 0.387 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.613 0.387 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.613 0.387 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.613 0.387 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.613 0.387 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.613 0.387 0.000
E16.2 Hypoglycaemia, unspecified
0.611 0.389 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.611 0.389 0.000
R94.7 Abnormal results of other endocrine function studies
0.611 0.389 0.000
R94.6 Abnormal results of thyroid function studies
0.611 0.389 0.000
R94.4 Abnormal results of kidney function studies
0.611 0.389 0.000
R94.2 Abnormal results of pulmonary function studies
0.611 0.389 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.611 0.389 0.000
R94.0 Abnormal results of function studies of central nervous system
0.611 0.389 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.611 0.389 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.610 0.390 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.610 0.390 0.000
L94 Other localised connective tissue disorders
0.610 0.390 0.000
L93 Lupus erythematosus
0.610 0.390 0.000
L87 Transepidermal elimination disorders
0.610 0.390 0.000
L88 Pyoderma gangrenosum
0.610 0.390 0.000
L86 Keratoderma in diseases classified elsewhere
0.610 0.390 0.000
L80 Vitiligo
0.610 0.390 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.610 0.390 0.000
N13.4 Hydroureter
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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