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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs146131423
log Bayes Factor = 14.8119
Chromosome 7   position 75,896,741  (GRCh37) Explore rs146131423 on Ensembl!
Variant rs146131423 is part of Cluster X0204

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
M51 Other intervertebral disk disorders
0.988 0.012 0.000
I20 Angina pectoris
0.986 0.014 0.000
I50 Heart failure
0.983 0.017 0.000
M51.2 Other specified intervertebral disk displacement
0.981 0.019 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.976 0.024 0.000
I45 Other conduction disorders
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.971 0.029 0.000
M54 Dorsalgia
0.971 0.029 0.000
I25.1 Atherosclerotic heart disease
0.968 0.032 0.000
I20.9 Angina pectoris, unspecified
0.967 0.033 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.966 0.034 0.000
A00-A09 Intestinal infectious diseases
0.965 0.035 0.000
M45-M49 Spondylopathies
0.961 0.039 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.957 0.043 0.000
M54.9 Dorsalgia, unspecified
0.955 0.045 0.000
I50.1 Left ventricular failure
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.952 0.048 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.948 0.052 0.000
I42 Cardiomyopathy
0.946 0.054 0.000
C15-C26 Malignant neoplasms of digestive organs
0.945 0.055 0.000
Chapter X Diseases of the respiratory system
0.943 0.057 0.000
I45.1 Other and unspecified right bundle-branch block
0.943 0.057 0.000
I25.2 Old myocardial infarction
0.942 0.058 0.000
I47 Paroxysmal tachycardia
0.938 0.062 0.000
I21 Acute myocardial infarction
0.936 0.064 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.934 0.066 0.000
A04 Other bacterial intestinal infections
0.932 0.068 0.000
I22 Subsequent myocardial infarction
0.928 0.072 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.922 0.078 0.000
I47.2 Ventricular tachycardia
0.918 0.082 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.916 0.084 0.000
J40-J47 Chronic lower respiratory diseases
0.916 0.084 0.000
C15 Malignant neoplasm of oesophagus
0.915 0.085 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.914 0.086 0.000
S40-S49 Injuries to the shoulder and upper arm
0.907 0.093 0.000
I20.0 Unstable angina
0.901 0.099 0.000
A04.8 Other specified bacterial intestinal infections
0.901 0.099 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.893 0.107 0.000
I51 Complications and ill-defined descriptions of heart disease
0.890 0.110 0.000
C51-C58 Malignant neoplasms of female genital organs
0.889 0.111 0.000
A41 Other septicaemia
0.888 0.112 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.884 0.116 0.000
I05-I09 Chronic rheumatic heart diseases
0.882 0.118 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.882 0.118 0.000
O60-O75 Complications of labour and delivery
0.881 0.119 0.000
I21.9 Acute myocardial infarction, unspecified
0.879 0.121 0.000
Chapter XIV Diseases of the genitourinary system
0.872 0.128 0.000
J44 Other chronic obstructive pulmonary disease
0.871 0.129 0.000
C77.2 Intra-abdominal lymph nodes
0.867 0.133 0.000
I34 Nonrheumatic mitral valve disorders
0.866 0.134 0.000
L03 Cellulitis
0.866 0.134 0.000
C78.0 Secondary malignant neoplasm of lung
0.864 0.136 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.861 0.139 0.000
I24 Other acute ischaemic heart diseases
0.859 0.141 0.000
Chapter VI Diseases of the nervous system
0.858 0.142 0.000
M80-M85 Disorders of bone density and structure
0.855 0.145 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.854 0.146 0.000
E65-E68 Obesity and other hyperalimentation
0.853 0.147 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.852 0.148 0.000
I42.0 Dilated cardiomyopathy
0.851 0.149 0.000
M47 Spondylosis
0.846 0.154 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.842 0.158 0.000
C15.9 Oesophagus, unspecified
0.840 0.160 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.840 0.160 0.000
M48 Other spondylopathies
0.834 0.166 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.833 0.167 0.000
E66 Obesity
0.832 0.168 0.000
S60-S69 Injuries to the wrist and hand
0.832 0.168 0.000
M45 Ankylosing spondylitis
0.828 0.172 0.000
L91 Hypertrophic disorders of skin
0.827 0.173 0.000
Chapter V Mental and behavioural disorders
0.826 0.174 0.000
A49 Bacterial infection of unspecified site
0.824 0.176 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.823 0.177 0.000
I45.9 Conduction disorder, unspecified
0.820 0.180 0.000
L20-L30 Dermatitis and eczema
0.816 0.184 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.812 0.188 0.000
E66.9 Obesity, unspecified
0.812 0.188 0.000
Chapter XXII Codes for special purposes
0.811 0.189 0.000
I50.0 Congestive heart failure
0.808 0.192 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.808 0.192 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.807 0.193 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.806 0.194 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.804 0.196 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.803 0.197 0.000
I51.8 Other ill-defined heart diseases
0.801 0.199 0.000
J95-J99 Other diseases of the respiratory system
0.799 0.201 0.000
I50.9 Heart failure, unspecified
0.798 0.202 0.000
I08 Multiple valve diseases
0.795 0.205 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.794 0.206 0.000
L84 Corns and callosities
0.794 0.206 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.793 0.207 0.000
L91.8 Other hypertrophic disorders of skin
0.788 0.212 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.785 0.214 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.785 0.215 0.000
S50-S59 Injuries to the elbow and forearm
0.783 0.217 0.000
D50-D53 Nutritional anaemias
0.783 0.217 0.000
N40-N51 Diseases of male genital organs
0.783 0.217 0.000
L03.1 Cellulitis of other parts of limb
0.783 0.217 0.000
N73 Other female pelvic inflammatory diseases
0.782 0.218 0.000
C15.5 Lower third of oesophagus
0.782 0.218 0.000
J47 Bronchiectasis
0.781 0.219 0.000
M91-M94 Chondropathies
0.780 0.220 0.000
S00-S09 Injuries to the head
0.779 0.221 0.000
I31 Other diseases of pericardium
0.779 0.221 0.000
M47.9 Spondylosis, unspecified
0.778 0.222 0.000
M60-M63 Disorders of muscles
0.778 0.222 0.000
C77.1 Intrathoracic lymph nodes
0.776 0.224 0.000
I10-I15 Hypertensive diseases
0.775 0.225 0.000
C15.4 Middle third of oesophagus
0.774 0.226 0.000
C17 Malignant neoplasm of small intestine
0.773 0.227 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.772 0.228 0.000
S80-S89 Injuries to the knee and lower leg
0.771 0.229 0.000
Chapter XXI Factors influencing health status and contact with health services
0.771 0.229 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.767 0.233 0.000
S42 Fracture of shoulder and upper arm
0.767 0.233 0.000
I42.9 Cardiomyopathy, unspecified
0.766 0.233 0.000
D00-D09 In situ neoplasms
0.766 0.234 0.000
L40-L45 Papulosquamous disorders
0.764 0.236 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.764 0.236 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.762 0.237 0.000
C56 Malignant neoplasm of ovary
0.761 0.238 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.760 0.240 0.000
M84 Disorders of continuity of bone
0.760 0.240 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.760 0.240 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.760 0.240 0.000
N30-N39 Other diseases of urinary system
0.757 0.243 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.756 0.244 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.755 0.245 0.000
Chapter XX External causes of morbidity and mortality
0.753 0.247 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.752 0.248 0.000
N73.6 Female pelvic peritoneal adhesions
0.752 0.248 0.000
C78.2 Secondary malignant neoplasm of pleura
0.752 0.248 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.751 0.249 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.750 0.250 0.000
I42.8 Other cardiomyopathies
0.749 0.251 0.000
M51.8 Other specified intervertebral disk disorders
0.749 0.251 0.000
B25-B34 Other viral diseases
0.748 0.252 0.000
M65-M68 Disorders of synovium and tendon
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.747 0.253 0.000
I22.8 Subsequent myocardial infarction of other sites
0.744 0.256 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.742 0.258 0.000
C64-C68 Malignant neoplasms of urinary tract
0.741 0.259 0.000
J46 Status asthmaticus
0.739 0.261 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.738 0.262 0.000
C77.5 Intrapelvic lymph nodes
0.738 0.262 0.000
S43.0 Dislocation of shoulder joint
0.737 0.263 0.000
A41.8 Other specified septicaemia
0.736 0.264 0.000
C77.3 Axillary and upper limb lymph nodes
0.735 0.265 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.734 0.265 0.000
M54.1 Radiculopathy
0.734 0.266 0.000
C77.0 Lymph nodes of head, face and neck
0.733 0.267 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.733 0.267 0.000
N00-N08 Glomerular diseases
0.731 0.269 0.000
C77.9 Lymph node, unspecified
0.731 0.269 0.000
L30 Other dermatitis
0.730 0.270 0.000
M54.3 Sciatica
0.730 0.270 0.000
I95 Hypotension
0.729 0.271 0.000
S10-S19 Injuries to the neck
0.726 0.274 0.000
A41.9 Septicaemia, unspecified
0.726 0.274 0.000
M54.4 Lumbago with sciatica
0.725 0.275 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.725 0.275 0.000
I34.0 Mitral (valve) insufficiency
0.724 0.276 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.720 0.279 0.000
A80-A89 Viral infections of the central nervous system
0.718 0.282 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.717 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
C80 Malignant neoplasm without specification of site
0.715 0.285 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
B95-B98 Bacterial, viral and other infectious agents
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
J84 Other interstitial pulmonary diseases
0.715 0.285 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.287 0.000
B65-B83 Helminthiases
0.712 0.287 0.000
B50-B64 Protozoal diseases
0.712 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.287 0.000
A75-A79 Rickettsioses
0.712 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.287 0.000
A65-A69 Other spirochaetal diseases
0.712 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.287 0.000
A15-A19 Tuberculosis
0.712 0.287 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.712 0.288 0.000
E70-E90 Metabolic disorders
0.712 0.288 0.000
J40 Bronchitis, not specified as acute or chronic
0.711 0.289 0.000
M48.0 Spinal stenosis
0.711 0.289 0.000
G51 Facial nerve disorders
0.711 0.289 0.000
I45.6 Preexcitation syndrome
0.710 0.290 0.000
B15-B19 Viral hepatitis
0.708 0.291 0.000
M51.3 Other specified intervertebral disk degeneration
0.708 0.292 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.708 0.292 0.000
M51.9 Intervertebral disk disorder, unspecified
0.708 0.292 0.000
M51.4 Schmorl's nodes
0.708 0.292 0.000
S40 Superficial injury of shoulder and upper arm
0.706 0.294 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.705 0.295 0.000
C51 Malignant neoplasm of vulva
0.705 0.295 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.703 0.297 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.703 0.297 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.702 0.298 0.000
I08.0 Disorders of both mitral and aortic valves
0.702 0.298 0.000
I34.1 Mitral (valve) prolapse
0.701 0.298 0.000
I42.2 Other hypertrophic cardiomyopathy
0.701 0.299 0.000
S69 Other and unspecified injuries of wrist and hand
0.701 0.299 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.700 0.300 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.700 0.300 0.000
I45.8 Other specified conduction disorders
0.699 0.301 0.000
I45.5 Other specified heart block
0.699 0.301 0.000
I45.4 Nonspecific intraventricular block
0.699 0.301 0.000
I45.3 Trifascicular block
0.699 0.301 0.000
I45.2 Bifascicular block
0.699 0.301 0.000
I45.0 Right fascicular block
0.699 0.301 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.698 0.302 0.000
L03.0 Cellulitis of finger and toe
0.698 0.302 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.697 0.303 0.000
O61 Failed induction of labour
0.697 0.303 0.000
L10-L14 Bullous disorders
0.696 0.303 0.000
M54.8 Other dorsalgia
0.696 0.304 0.000
M54.6 Pain in thoracic spine
0.696 0.304 0.000
M54.0 Panniculitis affecting regions of neck and back
0.696 0.304 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.696 0.304 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.696 0.304 0.000
S60 Superficial injury of wrist and hand
0.696 0.304 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.695 0.305 0.000
O72 Postpartum haemorrhage
0.694 0.306 0.000
L85 Other epidermal thickening
0.693 0.307 0.000
J60-J70 Lung diseases due to external agents
0.693 0.307 0.000
T33-T35 Frostbite
0.693 0.307 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.693 0.307 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
T00-T07 Injuries involving multiple body regions
0.693 0.307 0.000
N48 Other disorders of penis
0.692 0.308 0.000
A07 Other protozoal intestinal diseases
0.692 0.308 0.000
A06 Amoebiasis
0.692 0.308 0.000
A05 Other bacterial foodborne intoxications
0.692 0.308 0.000
A03 Shigellosis
0.692 0.308 0.000
A02 Other Salmonella infections
0.692 0.308 0.000
A01 Typhoid and paratyphoid fevers
0.692 0.308 0.000
A00 Cholera
0.692 0.308 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.692 0.308 0.000
O63 Long labour
0.692 0.308 0.000
M49 Spondylopathies in diseases classified elsewhere
0.689 0.311 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.688 0.312 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.688 0.312 0.000
O00-O08 Pregnancy with abortive outcome
0.687 0.313 0.000
I51.7 Cardiomegaly
0.686 0.314 0.000
C77.8 Lymph nodes of multiple regions
0.686 0.314 0.000
C77.4 Inguinal and lower limb lymph nodes
0.686 0.314 0.000
L05 Pilonidal cyst
0.686 0.314 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.685 0.315 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.685 0.315 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.685 0.315 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.685 0.315 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.685 0.315 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.685 0.315 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.685 0.315 0.000
S90-S99 Injuries to the ankle and foot
0.685 0.315 0.000
M46 Other inflammatory spondylopathies
0.685 0.315 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.685 0.315 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.685 0.315 0.000
M20-M25 Other joint disorders
0.684 0.316 0.000
B35-B49 Mycoses
0.683 0.317 0.000
A48 Other bacterial diseases, not elsewhere classified
0.682 0.318 0.000
A44 Bartonellosis
0.682 0.318 0.000
A43 Nocardiosis
0.682 0.318 0.000
A42 Actinomycosis
0.682 0.318 0.000
A40 Streptococcal septicaemia
0.682 0.318 0.000
A39 Meningococcal infection
0.682 0.318 0.000
A37 Whooping cough
0.682 0.318 0.000
A36 Diphtheria
0.682 0.318 0.000
A32 Listeriosis
0.682 0.318 0.000
A31 Infection due to other mycobacteria
0.682 0.318 0.000
A30 Leprosy [Hansen's disease]
0.682 0.318 0.000
A46 Erysipelas
0.682 0.318 0.000
A38 Scarlet fever
0.682 0.318 0.000
A35 Other tetanus
0.682 0.318 0.000
A34 Obstetrical tetanus
0.682 0.318 0.000
A33 Tetanus neonatorum
0.682 0.318 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.682 0.318 0.000
L91.0 Keloid scar
0.681 0.319 0.000
I20.1 Angina pectoris with documented spasm
0.681 0.319 0.000
J80 Adult respiratory distress syndrome
0.681 0.319 0.000
N99-N99 Other disorders of the genitourinary system
0.681 0.319 0.000
O85-O92 Complications predominantly related to the puerperium
0.679 0.320 0.000
I05 Rheumatic mitral valve diseases
0.679 0.321 0.000
D80-D89 Certain disorders involving the immune mechanism
0.679 0.321 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.678 0.322 0.000
I42.6 Alcoholic cardiomyopathy
0.678 0.322 0.000
I42.5 Other restrictive cardiomyopathy
0.678 0.322 0.000
I42.4 Endocardial fibroelastosis
0.678 0.322 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.678 0.322 0.000
J30-J39 Other diseases of upper respiratory tract
0.678 0.322 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.677 0.323 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.677 0.323 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.677 0.323 0.000
C21 Malignant neoplasm of anus and anal canal
0.677 0.323 0.000
C23 Malignant neoplasm of gallbladder
0.677 0.323 0.000
N76 Other inflammation of vagina and vulva
0.676 0.324 0.000
I21.4 Acute subendocardial myocardial infarction
0.676 0.324 0.000
A49.8 Other bacterial infections of unspecified site
0.675 0.325 0.000
C16 Malignant neoplasm of stomach
0.675 0.325 0.000
D51 Vitamin B12 deficiency anaemia
0.675 0.325 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.673 0.326 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.672 0.328 0.000
I47.0 Reentry ventricular arrhythmia
0.672 0.328 0.000
L03.9 Cellulitis, unspecified
0.672 0.328 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.671 0.329 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.671 0.329 0.000
C79 Secondary malignant neoplasm of other sites
0.671 0.329 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.669 0.331 0.000
D60-D64 Aplastic and other anaemias
0.669 0.331 0.000
L30.9 Dermatitis, unspecified
0.669 0.331 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.669 0.331 0.000
A04.9 Bacterial intestinal infection, unspecified
0.668 0.332 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.668 0.332 0.000
A04.4 Other intestinal Escherichia coli infections
0.668 0.332 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.668 0.332 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.668 0.332 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.668 0.332 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.668 0.332 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.666 0.333 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
N45 Orchitis and epididymitis
0.665 0.335 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.665 0.335 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.665 0.335 0.000
N43 Hydrocele and spermatocele
0.665 0.335 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.664 0.336 0.000
N35 Urethral stricture
0.664 0.336 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.662 0.338 0.000
I25.5 Ischaemic cardiomyopathy
0.661 0.338 0.000
L03.2 Cellulitis of face
0.661 0.339 0.000
O23 Infections of genito-urinary tract in pregnancy
0.661 0.339 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
N75 Diseases of Bartholin's gland
0.660 0.340 0.000
I46 Cardiac arrest
0.659 0.341 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.659 0.341 0.000
M47.2 Other spondylosis with radiculopathy
0.658 0.342 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.658 0.342 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.657 0.343 0.000
A08 Viral and other specified intestinal infections
0.657 0.343 0.000
L04 Acute lymphadenitis
0.657 0.343 0.000
L01 Impetigo
0.657 0.343 0.000
L00 Staphylococcal scalded skin syndrome
0.657 0.343 0.000
J41 Simple and mucopurulent chronic bronchitis
0.657 0.343 0.000
C15.8 Overlapping lesion of oesophagus
0.656 0.344 0.000
C15.3 Upper third of oesophagus
0.656 0.344 0.000
C15.2 Abdominal part of oesophagus
0.656 0.344 0.000
C15.1 Thoracic part of oesophagus
0.656 0.344 0.000
C15.0 Cervical part of oesophagus
0.656 0.344 0.000
T92 Sequelae of injuries of upper limb
0.655 0.345 0.000
N02 Recurrent and persistent haematuria
0.655 0.345 0.000
A49.9 Bacterial infection, unspecified
0.654 0.345 0.000
F99-F99 Unspecified mental disorder
0.654 0.346 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.654 0.346 0.000
J43 Emphysema
0.653 0.347 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.651 0.349 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.650 0.349 0.000
S48 Traumatic amputation of shoulder and upper arm
0.650 0.349 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.650 0.349 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.650 0.349 0.000
S44 Injury of nerves at shoulder and upper arm level
0.650 0.349 0.000
S41 Open wound of shoulder and upper arm
0.650 0.349 0.000
S47 Crushing injury of shoulder and upper arm
0.650 0.349 0.000
C17.9 Small intestine, unspecified
0.650 0.350 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.650 0.350 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.649 0.350 0.000
S42.4 Fracture of lower end of humerus
0.649 0.351 0.000
O70 Perineal laceration during delivery
0.646 0.354 0.000
G20-G26 Extrapyramidal and movement disorders
0.645 0.355 0.000
I44 Atrioventricular and left bundle-branch block
0.645 0.355 0.000
C81 Hodgkin's disease
0.645 0.355 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.645 0.355 0.000
G51.0 Bell's palsy
0.644 0.356 0.000
L08 Other local infections of skin and subcutaneous tissue
0.644 0.356 0.000
E66.8 Other obesity
0.643 0.357 0.000
S09 Other and unspecified injuries of head
0.641 0.359 0.000
J09-J18 Influenza and pneumonia
0.641 0.359 0.000
C91 Lymphoid leukaemia
0.641 0.359 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.640 0.360 0.000
C95 Leukaemia of unspecified cell type
0.640 0.360 0.000
C94 Other leukaemias of specified cell type
0.640 0.360 0.000
C93 Monocytic leukaemia
0.640 0.360 0.000
C88 Malignant immunoproliferative diseases
0.640 0.360 0.000
C86 Other specified types of T/NK-cell lymphoma
0.640 0.360 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.640 0.360 0.000
G30-G32 Other degenerative diseases of the nervous system
0.640 0.360 0.000
L50-L54 Urticaria and erythema
0.640 0.360 0.000
G70-G73 Diseases of myoneural junction and muscle
0.639 0.361 0.000
I51.6 Cardiovascular disease, unspecified
0.638 0.361 0.000
I51.5 Myocardial degeneration
0.638 0.361 0.000
I51.4 Myocarditis, unspecified
0.638 0.361 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.638 0.361 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.638 0.361 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.638 0.361 0.000
I51.0 Cardiac septal defect, acquired
0.638 0.361 0.000
L03.3 Cellulitis of trunk
0.638 0.362 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.638 0.362 0.000
C53 Malignant neoplasm of cervix uteri
0.638 0.362 0.000
C58 Malignant neoplasm of placenta
0.638 0.362 0.000
C52 Malignant neoplasm of vagina
0.638 0.362 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.637 0.363 0.000
A41.4 Septicaemia due to anaerobes
0.637 0.363 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.637 0.363 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.637 0.363 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.637 0.363 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.637 0.363 0.000
D50 Iron deficiency anaemia
0.636 0.364 0.000
M47.1 Other spondylosis with myelopathy
0.636 0.364 0.000
C20 Malignant neoplasm of rectum
0.635 0.365 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.635 0.365 0.000
I09 Other rheumatic heart diseases
0.633 0.367 0.000
I06 Rheumatic aortic valve diseases
0.633 0.367 0.000
D55-D59 Haemolytic anaemias
0.632 0.367 0.000
I10 Essential (primary) hypertension
0.632 0.368 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.632 0.368 0.000
O74 Complications of anaesthesia during labour and delivery
0.631 0.369 0.000
O73 Retained placenta and membranes, without haemorrhage
0.631 0.369 0.000
O71 Other obstetric trauma
0.631 0.369 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.631 0.369 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.631 0.369 0.000
O60 Preterm delivery
0.631 0.369 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.631 0.369 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.631 0.369 0.000
I31.3 Pericardial effusion (noninflammatory)
0.629 0.371 0.000
A49.0 Staphylococcal infection, unspecified
0.627 0.373 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.627 0.373 0.000
S50 Superficial injury of forearm
0.627 0.373 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.626 0.373 0.000
N39 Other disorders of urinary system
0.625 0.375 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.625 0.375 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.625 0.375 0.000
C60-C63 Malignant neoplasms of male genital organs
0.624 0.375 0.000
M54.2 Cervicalgia
0.624 0.376 0.000
O66 Other obstructed labour
0.623 0.377 0.000
M94 Other disorders of cartilage
0.622 0.377 0.000
F60-F69 Disorders of adult personality and behaviour
0.622 0.378 0.000
N72 Inflammatory disease of cervix uteri
0.621 0.379 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.621 0.379 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.621 0.379 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.621 0.379 0.000
L03.8 Cellulitis of other sites
0.621 0.379 0.000
S02 Fracture of skull and facial bones
0.620 0.380 0.000
I95.9 Hypotension, unspecified
0.620 0.380 0.000
M62 Other disorders of muscle
0.620 0.380 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.619 0.381 0.000
Z43 Attention to artificial openings
0.618 0.382 0.000
L43 Lichen planus
0.618 0.382 0.000
C54 Malignant neoplasm of corpus uteri
0.617 0.383 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.617 0.383 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.617 0.383 0.000
L94 Other localised connective tissue disorders
0.617 0.383 0.000
L93 Lupus erythematosus
0.617 0.383 0.000
L87 Transepidermal elimination disorders
0.617 0.383 0.000
L88 Pyoderma gangrenosum
0.617 0.383 0.000
L86 Keratoderma in diseases classified elsewhere
0.617 0.383 0.000
L83 Acanthosis nigricans
0.617 0.383 0.000
L80 Vitiligo
0.617 0.383 0.000
I51.9 Heart disease, unspecified
0.616 0.383 0.000
I24.1 Dressler's syndrome
0.616 0.384 0.000
M81 Osteoporosis without pathological fracture
0.616 0.384 0.000
S05 Injury of eye and orbit
0.616 0.384 0.000
M48.09 Spinal stenosis (Site unspecified)
0.615 0.385 0.000
C25 Malignant neoplasm of pancreas
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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