TreeWAS – Variant ID: rs1464510

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	0.000	0.001	0.999
C44.3 Skin of other and unspecified parts of face	0.000	0.002	0.998
C44.4 Skin of scalp and neck	0.000	0.013	0.987
C44.2 Skin of ear and external auricular canal	0.000	0.028	0.972
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.029	0.971
C44.5 Skin of trunk	0.000	0.066	0.934
C44.7 Skin of lower limb, including hip	0.000	0.094	0.906
C44.6 Skin of upper limb, including shoulder	0.000	0.180	0.820
E03 Other hypothyroidism	0.776	0.224	0.000
C44.0 Skin of lip	0.000	0.249	0.751
C44.8 Overlapping lesion of skin	0.000	0.283	0.716
J45.9 Asthma, unspecified	0.000	0.299	0.701
J45 Asthma	0.000	0.320	0.680
E03.8 Other specified hypothyroidism	0.679	0.321	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.327	0.673
J40 Bronchitis, not specified as acute or chronic	0.000	0.354	0.646
J45.0 Predominantly allergic asthma	0.000	0.372	0.628
J40-J47 Chronic lower respiratory diseases	0.000	0.377	0.623
E03.0 Congenital hypothyroidism with diffuse goitre	0.571	0.429	0.000
E03.5 Myxoedema coma	0.556	0.444	0.000
E03.4 Atrophy of thyroid (acquired)	0.556	0.444	0.000
E03.3 Postinfectious hypothyroidism	0.556	0.444	0.000
J45.8 Mixed asthma	0.000	0.453	0.547
E00-E07 Disorders of thyroid gland	0.534	0.466	0.000
J46 Status asthmaticus	0.000	0.471	0.529
E06 Thyroiditis	0.501	0.499	0.000
E03.1 Congenital hypothyroidism without goitre	0.500	0.499	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.493	0.507	0.000
E06.3 Autoimmune thyroiditis	0.457	0.543	0.000
E07 Other disorders of thyroid	0.452	0.548	0.000
E07.8 Other specified disorders of thyroid	0.422	0.578	0.000
J45.1 Nonallergic asthma	0.000	0.594	0.406
E06.9 Thyroiditis, unspecified	0.404	0.596	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.399	0.600	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.605	0.395
E06.5 Other chronic thyroiditis	0.384	0.616	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.383	0.617	0.000
E00 Congenital iodine-deficiency syndrome	0.383	0.617	0.000
E06.1 Subacute thyroiditis	0.368	0.632	0.000
E06.4 Drug-induced thyroiditis	0.359	0.641	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.359	0.641	0.000
E06.0 Acute thyroiditis	0.359	0.641	0.000
J42 Unspecified chronic bronchitis	0.000	0.656	0.344
E07.1 Dyshormogenetic goitre	0.324	0.676	0.000
E07.0 Hypersecretion of calcitonin	0.324	0.676	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.318	0.682	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.299	0.701	0.000
K90 Intestinal malabsorption	0.294	0.706	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.717	0.283
J41.1 Mucopurulent chronic bronchitis	0.000	0.717	0.283
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.274	0.725	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.274	0.725	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.274	0.725	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.274	0.725	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.274	0.725	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.274	0.725	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.274	0.725	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.274	0.725	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.761	0.239
J41.0 Simple chronic bronchitis	0.000	0.769	0.231
J43 Emphysema	0.000	0.769	0.231
K90.8 Other intestinal malabsorption	0.231	0.769	0.000
E05.5 Thyroid crisis or storm	0.228	0.771	0.000
E05.4 Thyrotoxicosis factitia	0.228	0.771	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.228	0.771	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.214	0.786	0.000
K90.3 Pancreatic steatorrhoea	0.211	0.789	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.211	0.789	0.000
K90.1 Tropical sprue	0.211	0.789	0.000
E07.9 Disorder of thyroid, unspecified	0.200	0.799	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.183	0.817	0.000
E05.9 Thyrotoxicosis, unspecified	0.168	0.832	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.168	0.832	0.000
J43.1 Panlobular emphysema	0.000	0.834	0.166
J43.0 MacLeod's syndrome	0.000	0.834	0.166
Chapter IV Endocrine, nutritional and metabolic diseases	0.157	0.843	0.000
J43.8 Other emphysema	0.000	0.844	0.156
E50-E64 Other nutritional deficiencies	0.149	0.851	0.000
E55 Vitamin D deficiency	0.147	0.853	0.000
E55.9 Vitamin D deficiency, unspecified	0.146	0.854	0.000
K90.9 Intestinal malabsorption, unspecified	0.142	0.858	0.000
E27 Other disorders of adrenal gland	0.135	0.865	0.000
E20-E35 Disorders of other endocrine glands	0.129	0.871	0.000
E27.1 Primary adrenocortical insufficiency	0.129	0.871	0.000
J43.2 Centrilobular emphysema	0.000	0.871	0.129
J47 Bronchiectasis	0.000	0.876	0.124
E27.4 Other and unspecified adrenocortical insufficiency	0.120	0.880	0.000
E54 Ascorbic acid deficiency	0.117	0.883	0.000
E40-E46 Malnutrition	0.117	0.883	0.000
E63 Other nutritional deficiencies	0.115	0.885	0.000
E51 Thiamine deficiency	0.113	0.887	0.000
E56 Other vitamin deficiencies	0.113	0.887	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.888	0.112
E27.3 Drug-induced adrenocortical insufficiency	0.112	0.888	0.000
E27.2 Addisonian crisis	0.110	0.890	0.000
E27.8 Other specified disorders of adrenal gland	0.109	0.891	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.107	0.893	0.000
E50 Vitamin A deficiency	0.107	0.893	0.000
E60 Dietary zinc deficiency	0.107	0.893	0.000
E59 Dietary selenium deficiency	0.107	0.893	0.000
E52 Niacin deficiency [pellagra]	0.107	0.893	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.893	0.107
E58 Dietary calcium deficiency	0.107	0.893	0.000
E55.0 Rickets, active	0.105	0.894	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.896	0.104
E28 Ovarian dysfunction	0.101	0.899	0.000
E65-E68 Obesity and other hyperalimentation	0.101	0.899	0.000
E05.8 Other thyrotoxicosis	0.100	0.899	0.002
E27.9 Disorder of adrenal gland, unspecified	0.101	0.899	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.100	0.900	0.000
E31 Polyglandular dysfunction	0.097	0.903	0.000
E27.5 Adrenomedullary hyperfunction	0.097	0.903	0.000
E27.0 Other adrenocortical overactivity	0.097	0.903	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.093	0.907	0.000
E32 Diseases of thymus	0.093	0.907	0.000
E30 Disorders of puberty, not elsewhere classified	0.093	0.907	0.000
E63.9 Nutritional deficiency, unspecified	0.090	0.910	0.000
E65 Localised adiposity	0.088	0.912	0.000
E46 Unspecified protein-energy malnutrition	0.088	0.912	0.000
E51.2 Wernicke's encephalopathy	0.088	0.912	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.912	0.088
E56.1 Deficiency of vitamin K	0.086	0.913	0.000
E26 Hyperaldosteronism	0.086	0.914	0.000
C43 Malignant melanoma of skin	0.000	0.915	0.085
J44 Other chronic obstructive pulmonary disease	0.000	0.916	0.084
E44 Protein-energy malnutrition of moderate and mild degree	0.084	0.916	0.000
E45 Retarded development following protein-energy malnutrition	0.084	0.916	0.000
E43 Unspecified severe protein-energy malnutrition	0.084	0.916	0.000
E42 Marasmic kwashiorkor	0.084	0.916	0.000
E41 Nutritional marasmus	0.084	0.916	0.000
E40 Kwashiorkor	0.084	0.916	0.000
E34 Other endocrine disorders	0.083	0.917	0.000
E29 Testicular dysfunction	0.083	0.917	0.000
E63.8 Other specified nutritional deficiencies	0.082	0.917	0.000
E63.1 Imbalance of constituents of food intake	0.082	0.917	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.082	0.917	0.000
E25 Adrenogenital disorders	0.082	0.918	0.000
E28.3 Primary ovarian failure	0.082	0.918	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.918	0.082
E51.9 Thiamine deficiency, unspecified	0.081	0.918	0.000
E51.8 Other manifestations of thiamine deficiency	0.081	0.918	0.000
E51.1 Beriberi	0.081	0.918	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.919	0.081
E56.9 Vitamin deficiency, unspecified	0.081	0.919	0.000
E56.8 Deficiency of other vitamins	0.081	0.919	0.000
E56.0 Deficiency of vitamin E	0.081	0.919	0.000
E23 Hypofunction and other disorders of pituitary gland	0.079	0.921	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.922	0.078
E61 Deficiency of other nutrient elements	0.078	0.922	0.000
E50.9 Vitamin A deficiency, unspecified	0.077	0.923	0.000
E50.8 Other manifestations of vitamin A deficiency	0.077	0.923	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.077	0.923	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.077	0.923	0.000
E50.5 Vitamin A deficiency with night blindness	0.077	0.923	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.077	0.923	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.077	0.923	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.077	0.923	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.077	0.923	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.077	0.923	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.077	0.923	0.000
E64.8 Sequelae of other nutritional deficiencies	0.077	0.923	0.000
E64.3 Sequelae of rickets	0.077	0.923	0.000
E64.2 Sequelae of vitamin C deficiency	0.077	0.923	0.000
E64.1 Sequelae of vitamin A deficiency	0.077	0.923	0.000
E64.0 Sequelae of protein-energy malnutrition	0.077	0.923	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.923	0.077
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.923	0.077
J43.9 Emphysema, unspecified	0.000	0.923	0.077
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.925	0.075
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.925	0.075
E31.0 Autoimmune polyglandular failure	0.074	0.926	0.000
E20 Hypoparathyroidism	0.073	0.927	0.000
E28.9 Ovarian dysfunction, unspecified	0.073	0.927	0.000
E28.8 Other ovarian dysfunction	0.073	0.927	0.000
E28.1 Androgen excess	0.073	0.927	0.000
E28.0 Oestrogen excess	0.073	0.927	0.000
E67 Other hyperalimentation	0.073	0.927	0.000
E68 Sequelae of hyperalimentation	0.073	0.927	0.000
E04 Other non-toxic goitre	0.072	0.928	0.000
E22 Hyperfunction of pituitary gland	0.072	0.928	0.000
E15 Nondiabetic hypoglycaemic coma	0.072	0.928	0.000
E28.2 Polycystic ovarian syndrome	0.072	0.928	0.000
E53 Deficiency of other B group vitamins	0.071	0.929	0.000
E31.9 Polyglandular dysfunction, unspecified	0.070	0.930	0.000
E31.8 Other polyglandular dysfunction	0.070	0.930	0.000
E31.1 Polyglandular hyperfunction	0.070	0.930	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.932	0.068
E30.9 Disorder of puberty, unspecified	0.067	0.933	0.000
E30.8 Other disorders of puberty	0.067	0.933	0.000
E30.1 Precocious puberty	0.067	0.933	0.000
E30.0 Delayed puberty	0.067	0.933	0.000
E32.9 Disease of thymus, unspecified	0.067	0.933	0.000
E32.8 Other diseases of thymus	0.067	0.933	0.000
E32.1 Abscess of thymus	0.067	0.933	0.000
E32.0 Persistent hyperplasia of thymus	0.067	0.933	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.067	0.933	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.067	0.933	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.067	0.933	0.000
E34.8 Other specified endocrine disorders	0.066	0.934	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.934	0.066
E34.3 Short stature, not elsewhere classified	0.065	0.935	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.936	0.064
E23.0 Hypopituitarism	0.064	0.936	0.000
E29.9 Testicular dysfunction, unspecified	0.063	0.937	0.000
E26.8 Other hyperaldosteronism	0.062	0.938	0.000
E26.1 Secondary hyperaldosteronism	0.062	0.938	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.939	0.061
C43.0 Malignant melanoma of lip	0.000	0.939	0.061
E26.9 Hyperaldosteronism, unspecified	0.061	0.939	0.000
E44.1 Mild protein-energy malnutrition	0.060	0.939	0.000
E44.0 Moderate protein-energy malnutrition	0.060	0.939	0.000
E23.7 Disorder of pituitary gland, unspecified	0.060	0.940	0.000
E34.5 Androgen resistance syndrome	0.060	0.940	0.000
E34.4 Constitutional tall stature	0.060	0.940	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.060	0.940	0.000
E34.1 Other hypersecretion of intestinal hormones	0.060	0.940	0.000
E29.8 Other testicular dysfunction	0.060	0.940	0.000
E29.0 Testicular hyperfunction	0.060	0.940	0.000
E25.9 Adrenogenital disorder, unspecified	0.059	0.941	0.000
E25.8 Other adrenogenital disorders	0.059	0.941	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.941	0.059
E16 Other disorders of pancreatic internal secretion	0.058	0.942	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.942	0.058
E24 Cushing's syndrome	0.057	0.942	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.057	0.943	0.000
E23.1 Drug-induced hypopituitarism	0.057	0.943	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.057	0.943	0.000
E34.9 Endocrine disorder, unspecified	0.057	0.943	0.000
E61.2 Magnesium deficiency	0.057	0.943	0.000
E61.9 Deficiency of nutrient element, unspecified	0.056	0.944	0.000
E61.8 Deficiency of other specified nutrient elements	0.056	0.944	0.000
E61.7 Deficiency of multiple nutrient elements	0.056	0.944	0.000
E61.6 Vanadium deficiency	0.056	0.944	0.000
E61.5 Molybdenum deficiency	0.056	0.944	0.000
E61.4 Chromium deficiency	0.056	0.944	0.000
E61.3 Manganese deficiency	0.056	0.944	0.000
E61.0 Copper deficiency	0.056	0.944	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.944	0.056
E26.0 Primary hyperaldosteronism	0.056	0.944	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.946	0.054
E20.8 Other hypoparathyroidism	0.053	0.947	0.000
E20.1 Pseudohypoparathyroidism	0.053	0.947	0.000
E20.0 Idiopathic hypoparathyroidism	0.053	0.947	0.000
E04.0 Non-toxic diffuse goitre	0.053	0.947	0.000
E67.8 Other specified hyperalimentation	0.052	0.947	0.000
E67.3 Hypervitaminosis D	0.052	0.947	0.000
E67.2 Megavitamin-B6 syndrome	0.052	0.947	0.000
E67.1 Hypercarotenaemia	0.052	0.947	0.000
E67.0 Hypervitaminosis A	0.052	0.947	0.000
E53.9 Vitamin B deficiency, unspecified	0.052	0.948	0.000
E04.8 Other specified non-toxic goitre	0.052	0.948	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.052	0.948	0.000
E22.8 Other hyperfunction of pituitary gland	0.052	0.948	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.052	0.948	0.000
E53.1 Pyridoxine deficiency	0.051	0.949	0.000
E53.0 Riboflavin deficiency	0.051	0.949	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.048	0.951	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.049	0.951	0.000
E23.6 Other disorders of pituitary gland	0.048	0.952	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.952	0.048
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.952	0.048
E22.1 Hyperprolactinaemia	0.046	0.954	0.000
E16.1 Other hypoglycaemia	0.045	0.955	0.000
E29.1 Testicular hypofunction	0.044	0.956	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.044	0.956	0.000
E22.0 Acromegaly and pituitary gigantism	0.044	0.956	0.000
E21.4 Other specified disorders of parathyroid gland	0.043	0.956	0.000
E24.0 Pituitary-dependent Cushing's disease	0.043	0.957	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.957	0.043
M05.1 Rheumatoid lung disease	0.000	0.957	0.043
E21.2 Other hyperparathyroidism	0.042	0.958	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.042	0.958	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.042	0.958	0.000
E16.4 Abnormal secretion of gastrin	0.042	0.958	0.000
E16.3 Increased secretion of glucagon	0.042	0.958	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.958	0.042
M05.0 Felty's syndrome	0.000	0.958	0.042
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.041	0.958	0.000
E24.3 Ectopic ACTH syndrome	0.041	0.958	0.000
E24.1 Nelson's syndrome	0.041	0.958	0.000
M05.2 Rheumatoid vasculitis	0.000	0.959	0.041
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.959	0.041
E24.8 Other Cushing's syndrome	0.037	0.963	0.000
E23.2 Diabetes insipidus	0.037	0.963	0.000
N75.0 Cyst of Bartholin's gland	0.036	0.964	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.965	0.035
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.965	0.035
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.965	0.035
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.965	0.035
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.965	0.035
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.965	0.035
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.965	0.035
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.965	0.035
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.965	0.035
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.965	0.035
E20.9 Hypoparathyroidism, unspecified	0.033	0.967	0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.032	0.968	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.968	0.032
E24.2 Drug-induced Cushing's syndrome	0.031	0.968	0.000
M05.18 Rheumatoid lung disease (Other)	0.000	0.969	0.031
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.969	0.031
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.969	0.031
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.969	0.031
M05.14 Rheumatoid lung disease (Hand)	0.000	0.969	0.031
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.969	0.031
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.969	0.031
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.969	0.031
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.969	0.031
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.969	0.030
M05.09 Felty's syndrome (Site unspecified)	0.000	0.970	0.030
M05.08 Felty's syndrome (Other)	0.000	0.970	0.030
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.970	0.030
M05.06 Felty's syndrome (Lower leg)	0.000	0.970	0.030
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.970	0.030
M05.04 Felty's syndrome (Hand)	0.000	0.970	0.030
M05.03 Felty's syndrome (Forearm)	0.000	0.970	0.030
M05.02 Felty's syndrome (Upper arm)	0.000	0.970	0.030
M05.01 Felty's syndrome (Shoulder region)	0.000	0.970	0.030
M05.00 Felty's syndrome (Multiple sites)	0.000	0.970	0.030
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.970	0.030
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.970	0.030
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.970	0.030
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.970	0.030
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.970	0.030
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.970	0.030
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.970	0.030
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.970	0.030
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.970	0.030
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.970	0.030
M05.28 Rheumatoid vasculitis (Other)	0.000	0.970	0.030
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.970	0.030
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.970	0.030
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.970	0.030
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.970	0.030
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.970	0.030
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.970	0.030
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.970	0.030
E04.2 Non-toxic multinodular goitre	0.030	0.970	0.000
E24.9 Cushing's syndrome, unspecified	0.029	0.971	0.000
E34.0 Carcinoid syndrome	0.028	0.971	0.001
N75 Diseases of Bartholin's gland	0.029	0.971	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.971	0.028
N75.1 Abscess of Bartholin's gland	0.026	0.974	0.000
E10-E14 Diabetes mellitus	0.025	0.975	0.000
N75.8 Other diseases of Bartholin's gland	0.025	0.975	0.000
E61.1 Iron deficiency	0.025	0.975	0.000
K90-K93 Other diseases of the digestive system	0.022	0.978	0.000
E21.3 Hyperparathyroidism, unspecified	0.022	0.978	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.021	0.979	0.000
E12 Malnutrition-related diabetes mellitus	0.018	0.981	0.000
E10.4 With neurological complications	0.018	0.982	0.000
E16.2 Hypoglycaemia, unspecified	0.017	0.983	0.000
E10 Insulin-dependent diabetes mellitus	0.017	0.983	0.000
E04.1 Non-toxic single thyroid nodule	0.017	0.983	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.983	0.017
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.983	0.017
K93 Disorders of other digestive organs in diseases classified elsewhere	0.016	0.984	0.000
E10.2 With renal complications	0.015	0.985	0.000
E66 Obesity	0.015	0.985	0.000
E10.0 With coma	0.014	0.986	0.000
I38 Endocarditis, valve unspecified	0.000	0.986	0.014
E10.7 With multiple complications	0.014	0.986	0.000
E12.9 Without complications	0.013	0.986	0.000
E12.8 With unspecified complications	0.013	0.986	0.000
E12.7 With multiple complications	0.013	0.986	0.000
E12.6 With other specified complications	0.013	0.986	0.000
E12.5 With peripheral circulatory complications	0.013	0.986	0.000
E12.4 With neurological complications	0.013	0.986	0.000
E12.3 With ophthalmic complications	0.013	0.986	0.000
E12.2 With renal complications	0.013	0.986	0.000
E12.1 With ketoacidosis	0.013	0.986	0.000
E12.0 With coma	0.013	0.986	0.000
E70-E90 Metabolic disorders	0.013	0.987	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.013	0.987	0.000
E10.5 With peripheral circulatory complications	0.013	0.987	0.000
E13 Other specified diabetes mellitus	0.012	0.987	0.000
E04.9 Non-toxic goitre, unspecified	0.012	0.988	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.988	0.012
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.012	0.988	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.012	0.988	0.000
K93.1 Megacolon in Chagas' disease	0.012	0.988	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.012	0.988	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.988	0.012
E80 Disorders of porphyrin and bilirubin metabolism	0.012	0.988	0.000
E73 Lactose intolerance	0.011	0.989	0.000
E89.4 Postprocedural ovarian failure	0.011	0.989	0.000
E84 Cystic fibrosis	0.011	0.989	0.000
E10.6 With other specified complications	0.011	0.989	0.000
E53.8 Deficiency of other specified B group vitamins	0.011	0.989	0.000
O43.8 Other placental disorders	0.011	0.989	0.000
O43.1 Malformation of placenta	0.011	0.989	0.000
E66.1 Drug-induced obesity	0.011	0.989	0.000
E74 Other disorders of carbohydrate metabolism	0.011	0.989	0.000
E80.4 Gilbert's syndrome	0.011	0.989	0.000
E89.0 Postprocedural hypothyroidism	0.011	0.989	0.000
N81.8 Other female genital prolapse	0.000	0.989	0.011
O43 Placental disorders	0.010	0.990	0.000
E89.2 Postprocedural hypoparathyroidism	0.010	0.990	0.000
E66.0 Obesity due to excess calories	0.010	0.990	0.000
E10.8 With unspecified complications	0.010	0.990	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.010	0.990	0.000
E73.9 Lactose intolerance, unspecified	0.010	0.990	0.000
O43.0 Placental transfusion syndromes	0.010	0.990	0.000
E84.9 Cystic fibrosis, unspecified	0.010	0.990	0.000
C43.5 Malignant melanoma of trunk	0.000	0.990	0.010
E77 Disorders of glycoprotein metabolism	0.010	0.990	0.000
E76 Disorders of glycosaminoglycan metabolism	0.010	0.990	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.010	0.990	0.000
E70 Disorders of aromatic amino-acid metabolism	0.010	0.990	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.010	0.990	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.010	0.990	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.010	0.990	0.000
E89.5 Postprocedural testicular hypofunction	0.010	0.990	0.000
E89.1 Postprocedural hypoinsulinaemia	0.009	0.990	0.000
E79 Disorders of purine and pyrimidine metabolism	0.009	0.990	0.000
E13.8 With unspecified complications	0.009	0.991	0.000
E13.7 With multiple complications	0.009	0.991	0.000
E13.6 With other specified complications	0.009	0.991	0.000
E13.5 With peripheral circulatory complications	0.009	0.991	0.000
E13.4 With neurological complications	0.009	0.991	0.000
E13.3 With ophthalmic complications	0.009	0.991	0.000
E13.2 With renal complications	0.009	0.991	0.000
E13.1 With ketoacidosis	0.009	0.991	0.000
E13.0 With coma	0.009	0.991	0.000
E72 Other disorders of amino-acid metabolism	0.009	0.991	0.000
T93 Sequelae of injuries of lower limb	0.000	0.991	0.009
E89.3 Postprocedural hypopituitarism	0.009	0.991	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.009	0.991	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.009	0.991	0.000
E80.6 Other disorders of bilirubin metabolism	0.009	0.991	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.991	0.009
E80.7 Disorder of bilirubin metabolism, unspecified	0.008	0.991	0.000
E80.5 Crigler-Najjar syndrome	0.008	0.991	0.000
E80.3 Defects of catalase and peroxydase	0.008	0.991	0.000
E80.2 Other porphyria	0.008	0.991	0.000
E80.0 Hereditary erythropoietic porphyria	0.008	0.991	0.000
E73.8 Other lactose intolerance	0.008	0.991	0.000
E73.1 Secondary lactase deficiency	0.008	0.991	0.000
E73.0 Congenital lactase deficiency	0.008	0.991	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.008	0.992	0.000
E84.8 Cystic fibrosis with other manifestations	0.008	0.992	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.008	0.992	0.000
E14 Unspecified diabetes mellitus	0.008	0.992	0.000
T93.1 Sequelae of fracture of femur	0.000	0.992	0.008
A49.8 Other bacterial infections of unspecified site	0.000	0.992	0.008
Z57.5 Occupational exposure to toxic agents in other industries	0.008	0.992	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.008	0.992	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.008	0.992	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.008	0.992	0.000
E74.2 Disorders of galactose metabolism	0.008	0.992	0.000
E74.1 Disorders of fructose metabolism	0.008	0.992	0.000
E10.1 With ketoacidosis	0.008	0.992	0.000
E74.0 Glycogen storage disease	0.008	0.992	0.000
O43.2 Morbidly adherent placenta	0.008	0.992	0.000
E14.2 Withrenal complications	0.008	0.992	0.000
E80.1 Porphyria cutanea tarda	0.007	0.993	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.007	0.993	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.007	0.993	0.000
E70.3 Albinism	0.007	0.993	0.000
E70.2 Disorders of tyrosine metabolism	0.007	0.993	0.000
E70.1 Other hyperphenylalaninaemias	0.007	0.993	0.000
E70.0 Classical phenylketonuria	0.007	0.993	0.000
E71.3 Disorders of fatty-acid metabolism	0.007	0.993	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.007	0.993	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.007	0.993	0.000
E71.0 Maple-syrup-urine disease	0.007	0.993	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.007	0.993	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.007	0.993	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.007	0.993	0.000
E76.2 Other mucopolysaccharidoses	0.007	0.993	0.000
E76.1 Mucopolysaccharidosis, type II	0.007	0.993	0.000
E76.0 Mucopolysaccharidosis, type I	0.007	0.993	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.007	0.993	0.000
E77.8 Other disorders of glycoprotein metabolism	0.007	0.993	0.000
E77.1 Defects in glycoprotein degradation	0.007	0.993	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.007	0.993	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.993	0.007
T91 Sequelae of injuries of neck and trunk	0.000	0.993	0.007
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.993	0.007
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.007	0.993	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.007	0.993	0.000
E79.1 Lesch-Nyhan syndrome	0.007	0.993	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.007	0.993	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.007	0.993	0.000
E72.5 Disorders of glycine metabolism	0.007	0.993	0.000
E72.4 Disorders of ornithine metabolism	0.007	0.993	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.007	0.993	0.000
E72.2 Disorders of urea cycle metabolism	0.007	0.993	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.007	0.993	0.000
E11.2 With renal complications	0.007	0.993	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.993	0.007
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.993	0.007
K91.3 Postoperative intestinal obstruction	0.000	0.993	0.007
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.993	0.007
E85 Amyloidosis	0.007	0.993	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.007	0.993	0.000
W22.9 Unspecified place	0.007	0.993	0.000
E75.6 Lipid storage disorder, unspecified	0.006	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations