TreeWAS – Variant ID: rs1476029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.129	0.871	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.128	0.872	0.000
Y52 Agents primarily affecting the cardiovascular system	0.126	0.874	0.000
Y42.5 Other oestrogens and progestogens	0.126	0.874	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.125	0.875	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.119	0.881	0.000
Y45.8 Other analgesics and antipyretics	0.119	0.881	0.000
Y44 Agents primarily affecting blood constituents	0.118	0.882	0.000
Y45.1 Salicylates	0.117	0.883	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.117	0.883	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.114	0.886	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.111	0.889	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.108	0.892	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.106	0.894	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.104	0.896	0.000
Y44.2 Anticoagulants	0.104	0.896	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.100	0.900	0.000
Y42.2 Antithyroid drugs	0.099	0.900	0.000
Y58 Bacterial vaccines	0.099	0.901	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.096	0.904	0.000
Y44.5 Thrombolytic drugs	0.095	0.905	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.094	0.905	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.094	0.906	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.094	0.906	0.000
Y42.9 Other and unspecified hormone antagonists	0.093	0.907	0.000
Y42.4 Oral contraceptives	0.093	0.907	0.000
Y42.1 Thyroid hormones and substitutes	0.093	0.907	0.000
Y59 Other and unspecified vaccines and biological substances	0.092	0.908	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.092	0.908	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.092	0.908	0.000
Y45.0 Opioids and related analgesics	0.092	0.908	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.092	0.908	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.091	0.909	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.090	0.909	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.090	0.909	0.000
Y52.7 Peripheral vasodilators	0.090	0.909	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.090	0.910	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.090	0.910	0.000
Y45.4 Antirheumatics	0.089	0.910	0.000
Y52.1 Calcium-channel blockers	0.088	0.911	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.087	0.913	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.085	0.915	0.000
Y44.7 Plasma substitutes	0.085	0.915	0.000
Y44.6 Natural blood and blood products	0.085	0.915	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.085	0.915	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.085	0.915	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.085	0.915	0.000
Y45.5 4-Aminophenol derivatives	0.084	0.915	0.000
Y48 Anaesthetics and therapeutic gases	0.084	0.916	0.000
Y40 Systemic antibiotics	0.080	0.920	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.079	0.920	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.079	0.920	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.079	0.920	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.079	0.920	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.079	0.920	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.079	0.920	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.079	0.920	0.000
Y51.0 Anticholinesterase agents	0.079	0.920	0.000
Y58.0 BCG vaccine	0.078	0.922	0.000
Y57 Other and unspecified drugs and medicaments	0.078	0.922	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.077	0.923	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.076	0.924	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.076	0.924	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.076	0.924	0.000
Y40.8 Other systemic antibiotics	0.074	0.926	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.072	0.927	0.000
Y43 Primarily systemic agents	0.072	0.928	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.071	0.929	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.071	0.929	0.000
Y58.9 Other and unspecified bacterial vaccines	0.071	0.929	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.071	0.929	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.071	0.929	0.000
Y58.5 Diphtheria vaccine	0.071	0.929	0.000
Y58.4 Tetanus vaccine	0.071	0.929	0.000
Y58.3 Plague vaccine	0.071	0.929	0.000
Y58.2 Cholera vaccine	0.071	0.929	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.071	0.929	0.000
Y46.2 Hydantoin derivatives	0.071	0.929	0.000
Y47.1 Benzodiazepines	0.071	0.929	0.000
Y56.9 Topical agent, unspecified	0.069	0.931	0.000
Y56.8 Other topical agents	0.069	0.931	0.000
Y56.7 Dental drugs, topically applied	0.069	0.931	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.069	0.931	0.000
Y56.5 Ophthalmological drugs and preparations	0.069	0.931	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.069	0.931	0.000
Y56.3 Emollients, demulcents and protectants	0.069	0.931	0.000
Y56.2 Local astringents and local detergents	0.069	0.931	0.000
Y56.1 Antipruritics	0.069	0.931	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.068	0.932	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.068	0.932	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.068	0.932	0.000
Y47.4 Bromine compounds	0.068	0.932	0.000
Y47.3 Paraldehyde	0.068	0.932	0.000
Y47.2 Chloral derivatives	0.068	0.932	0.000
Y47.0 Barbiturates, not elsewhere classified	0.068	0.932	0.000
Y49.2 Other and unspecified antidepressants	0.066	0.933	0.000
Y50.9 Central nervous system stimulant, unspecified	0.066	0.934	0.000
Y50.8 Other central nervous system stimulants	0.066	0.934	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.066	0.934	0.000
Y50.1 Opioid receptor antagonists	0.066	0.934	0.000
Y50.0 Analeptics	0.066	0.934	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.066	0.934	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.066	0.934	0.000
Y55.5 Anticommon cold drugs	0.066	0.934	0.000
Y55.4 Expectorants	0.066	0.934	0.000
Y55.3 Antitussives	0.066	0.934	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.066	0.934	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.066	0.934	0.000
Y55.0 Oxytocic drugs	0.066	0.934	0.000
Y59.9 Vaccine or biological substance, unspecified	0.066	0.934	0.000
Y59.8 Other specified vaccines and biological substances	0.066	0.934	0.000
Y59.3 Immunoglobulin	0.066	0.934	0.000
Y59.2 Protozoal vaccines	0.066	0.934	0.000
Y59.1 Rickettsial vaccines	0.066	0.934	0.000
Y59.0 Viral vaccines	0.066	0.934	0.000
Y49.9 Psychotropic drug, unspecified	0.065	0.935	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.065	0.935	0.000
Y49.7 Psychostimulants with abuse potential	0.065	0.935	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.065	0.935	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.065	0.935	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.065	0.935	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.065	0.935	0.000
Y46.8 Antispasticity drugs	0.064	0.935	0.000
Y46.7 Anti-Parkinsonism drugs	0.064	0.935	0.000
Y46.5 Valproic acid	0.064	0.935	0.000
Y46.3 Deoxybarbiturates	0.064	0.935	0.000
Y46.1 Oxazolidinediones	0.064	0.935	0.000
Y46.0 Succinimides	0.064	0.935	0.000
Y57.6 Other diagnostic agents	0.064	0.936	0.000
I71 Aortic aneurysm and dissection	0.063	0.937	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.062	0.938	0.000
Y46.6 Other and unspecified antiepileptics	0.061	0.939	0.000
Y48.5 Therapeutic gases	0.060	0.939	0.000
Y48.4 Anaesthetic, unspecified	0.060	0.939	0.000
Y48.1 Parenteral anaesthetics	0.060	0.939	0.000
Y48.0 Inhaled anaesthetics	0.060	0.939	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.060	0.940	0.000
Y43.4 Immunosuppressive agents	0.060	0.940	0.000
Y43.0 Antiallergic and antiemetic drugs	0.058	0.942	0.000
Y40.7 Antifungal antibiotics, systemically used	0.058	0.942	0.000
Y40.6 Rifamycins	0.058	0.942	0.000
Y40.5 Aminoglycosides	0.058	0.942	0.000
Y40.4 Tetracyclines	0.058	0.942	0.000
Y40.2 Chloramphenicol group	0.058	0.942	0.000
Y46.4 Iminostilbenes	0.058	0.942	0.000
Y40.0 Penicillins	0.058	0.942	0.000
Y48.3 Local anaesthetics	0.057	0.942	0.000
Y57.5 X-ray contrast media	0.057	0.942	0.000
I71.0 Dissection of aorta [any part]	0.057	0.943	0.000
Y41.0 Sulphonamides	0.057	0.943	0.000
Y48.2 Other and unspecified general anaesthetics	0.056	0.943	0.000
Y57.7 Vitamins, not elsewhere classified	0.056	0.944	0.000
Y57.4 Pharmaceutical excipients	0.056	0.944	0.000
Y57.3 Alcohol deterrents	0.056	0.944	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.056	0.944	0.000
Y57.1 Lipotropic drugs	0.056	0.944	0.000
Y57.0 Appetite depressants [anorectics]	0.056	0.944	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.056	0.944	0.000
Y45.2 Propionic acid derivatives	0.055	0.945	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.055	0.945	0.000
Y41.4 Anthelminthics	0.055	0.945	0.000
Y41.3 Other antiprotozoal drugs	0.055	0.945	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.055	0.945	0.000
Y41.1 Antimycobacterial drugs	0.055	0.945	0.000
Y49.5 Other antipsychotics and neuroleptics	0.053	0.947	0.000
Y43.9 Primarily systemic agent, unspecified	0.052	0.948	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.052	0.948	0.000
Y43.6 Enzymes, not elsewhere classified	0.052	0.948	0.000
Y43.5 Acidifying and alkalising agents	0.052	0.948	0.000
Y43.2 Antineoplastic natural products	0.052	0.948	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.051	0.948	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.051	0.949	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.051	0.949	0.000
Y53.7 Emetics	0.051	0.949	0.000
Y53.6 Antidiarrhoeal drugs	0.051	0.949	0.000
Y53.5 Digestants	0.051	0.949	0.000
Y53.3 Saline and osmotic laxatives	0.051	0.949	0.000
Y53.2 Stimulant laxatives	0.051	0.949	0.000
Y53.0 Histamine H2-receptor antagonists	0.051	0.949	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.051	0.949	0.000
Y57.8 Other drugs and medicaments	0.050	0.950	0.000
Y41.5 Antiviral drugs	0.049	0.950	0.000
Y42.7 Androgens and anabolic congeners	0.048	0.952	0.000
Y53.4 Other laxatives	0.047	0.953	0.000
Q21.1 Atrial septal defect	0.000	0.954	0.046
I71.8 Aortic aneurysm of unspecified site, ruptured	0.045	0.955	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.045	0.955	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.045	0.955	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.043	0.957	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.043	0.957	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.043	0.957	0.000
Y40.3 Macrolides	0.042	0.957	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.042	0.958	0.000
Y54.7 Agents affecting calcification	0.041	0.958	0.000
Y43.1 Antineoplastic antimetabolites	0.040	0.959	0.000
I74 Arterial embolism and thrombosis	0.041	0.959	0.000
Y54.9 Mineral salts, not elsewhere classified	0.040	0.960	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.040	0.960	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.040	0.960	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.040	0.960	0.000
Y54.0 Mineralocorticoids	0.040	0.960	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.039	0.961	0.000
Y54.4 Loop [high-ceiling] diuretics	0.039	0.961	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.039	0.961	0.000
Y54.8 Agents affecting uric acid metabolism	0.039	0.961	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.039	0.961	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.037	0.962	0.001
I74.5 Embolism and thrombosis of iliac artery	0.036	0.964	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.036	0.964	0.000
Y54.5 Other diuretics	0.033	0.966	0.000
Y57.9 Drug or medicament, unspecified	0.033	0.967	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.032	0.968	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.032	0.968	0.000
Y40.9 Systemic antibiotic, unspecified	0.031	0.969	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.029	0.970	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.028	0.972	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.027	0.973	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.027	0.973	0.000
I72 Other aneurysm	0.026	0.974	0.000
I78 Diseases of capillaries	0.026	0.974	0.000
I74.8 Embolism and thrombosis of other arteries	0.024	0.976	0.000
R22.2 Localised swelling, mass and lump, trunk	0.024	0.976	0.000
I77 Other disorders of arteries and arterioles	0.023	0.977	0.000
S01.8 Open wound of other parts of head	0.000	0.977	0.023
R22.0 Localised swelling, mass and lump, head	0.023	0.977	0.000
I70 Atherosclerosis	0.023	0.977	0.000
Y54.3 Benzothiadiazine derivatives	0.022	0.978	0.001
Q21 Congenital malformations of cardiac septa	0.000	0.978	0.022
R22.9 Localised swelling, mass and lump, unspecified	0.022	0.978	0.000
I72.9 Aneurysm of unspecified site	0.022	0.978	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.021	0.979	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.021	0.979	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.021	0.979	0.000
I72.4 Aneurysm of artery of lower extremity	0.021	0.979	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.020	0.980	0.000
I79.1 Aortitis in diseases classified elsewhere	0.020	0.980	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.020	0.980	0.000
I72.3 Aneurysm of iliac artery	0.020	0.980	0.000
I77.1 Stricture of artery	0.020	0.980	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.019	0.981	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.019	0.981	0.000
I72.1 Aneurysm of artery of upper extremity	0.019	0.981	0.000
I78.9 Disease of capillaries, unspecified	0.019	0.981	0.000
I78.8 Other diseases of capillaries	0.019	0.981	0.000
I77.2 Rupture of artery	0.018	0.982	0.000
I77.8 Other specified disorders of arteries and arterioles	0.017	0.983	0.000
I72.8 Aneurysm of other specified arteries	0.017	0.983	0.000
I72.2 Aneurysm of renal artery	0.017	0.983	0.000
I70.1 Atherosclerosis of renal artery	0.017	0.983	0.000
I77.5 Necrosis of artery	0.017	0.983	0.000
I77.4 Coeliac artery compression syndrome	0.017	0.983	0.000
I77.3 Arterial fibromuscular dysplasia	0.017	0.983	0.000
Y43.3 Other antineoplastic drugs	0.017	0.983	0.000
I70.9 Generalised and unspecified atherosclerosis	0.016	0.984	0.000
I70.8 Atherosclerosis of other arteries	0.016	0.984	0.000
Q21.0 Ventricular septal defect	0.000	0.984	0.016
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.984	0.016
Q21.8 Other congenital malformations of cardiac septa	0.000	0.984	0.016
Q21.4 Aortopulmonary septal defect	0.000	0.984	0.016
Q21.3 Tetralogy of Fallot	0.000	0.984	0.016
Q21.2 Atrioventricular septal defect	0.000	0.984	0.016
R22.3 Localised swelling, mass and lump, upper limb	0.016	0.984	0.000
I70.0 Atherosclerosis of aorta	0.015	0.985	0.000
R22.1 Localised swelling, mass and lump, neck	0.015	0.985	0.000
I72.0 Aneurysm of carotid artery	0.014	0.985	0.000
I78.1 Naevus, nonneoplastic	0.014	0.986	0.000
Z48.8 Other specified surgical follow-up care	0.014	0.986	0.000
I77.0 Arteriovenous fistula, acquired	0.014	0.986	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.014	0.986	0.000
J33.0 Polyp of nasal cavity	0.014	0.986	0.000
I77.6 Arteritis, unspecified	0.014	0.986	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.013	0.987	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.012	0.988	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.012	0.988	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.012	0.988	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.012	0.988	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.012	0.988	0.000
M84.03 Malunion of fracture (Forearm)	0.012	0.988	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.012	0.988	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.012	0.988	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.011	0.989	0.000
M84.0 Malunion of fracture	0.011	0.989	0.000
I73 Other peripheral vascular diseases	0.010	0.990	0.000
M84.02 Malunion of fracture (Upper arm)	0.010	0.990	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.010	0.990	0.000
M84.01 Malunion of fracture (Shoulder region)	0.010	0.990	0.000
I80 Phlebitis and thrombophlebitis	0.009	0.991	0.000
Z48 Other surgical follow-up care	0.009	0.991	0.000
Z48.9 Surgical follow-up care, unspecified	0.009	0.991	0.000
C67 Malignant neoplasm of bladder	0.009	0.991	0.000
I73.8 Other specified peripheral vascular diseases	0.008	0.992	0.000
G91.9 Hydrocephalus, unspecified	0.008	0.992	0.000
C67.5 Bladder neck	0.008	0.992	0.000
M84.09 Malunion of fracture (Site unspecified)	0.008	0.992	0.000
M84.08 Malunion of fracture (Other)	0.008	0.992	0.000
M84.06 Malunion of fracture (Lower leg)	0.008	0.992	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.008	0.992	0.000
M84.00 Malunion of fracture (Multiple sites)	0.008	0.992	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.008	0.992	0.000
M84.04 Malunion of fracture (Hand)	0.008	0.992	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.008	0.992	0.000
C67.8 Overlapping lesion of bladder	0.008	0.992	0.000
C67.2 Lateral wall of bladder	0.008	0.992	0.000
M84 Disorders of continuity of bone	0.008	0.992	0.000
C67.0 Trigone of bladder	0.008	0.992	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.008	0.992	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.007	0.992	0.000
C67.4 Posterior wall of bladder	0.007	0.993	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.007	0.993	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.007	0.993	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.007	0.993	0.000
K56.6 Other and unspecified intestinal obstruction	0.007	0.993	0.000
C67.6 Ureteric orifice	0.007	0.993	0.000
G91 Hydrocephalus	0.007	0.993	0.000
C67.3 Anterior wall of bladder	0.007	0.993	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.007	0.993	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.007	0.993	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.006	0.994	0.000
C67.7 Urachus	0.006	0.994	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.006	0.994	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.006	0.994	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.006	0.994	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.006	0.994	0.000
G90-G99 Other disorders of the nervous system	0.006	0.994	0.000
M84.9 Disorder of continuity of bone, unspecified	0.006	0.994	0.000
M84.8 Other disorders of continuity of bone	0.006	0.994	0.000
M84.3 Stress fracture, not elsewhere classified	0.006	0.994	0.000
M84.2 Delayed union of fracture	0.006	0.994	0.000
G94.1 Hydrocephalus in neoplastic disease	0.006	0.994	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.006	0.994	0.000
G91.1 Obstructive hydrocephalus	0.006	0.994	0.000
M84.4 Pathological fracture, not elsewhere classified	0.006	0.994	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.006	0.994	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.006	0.994	0.000
G91.2 Normal-pressure hydrocephalus	0.006	0.994	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.005	0.994	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.005	0.994	0.000
Z43.2 Attention to ileostomy	0.005	0.995	0.000
G90 Disorders of autonomic nervous system	0.005	0.995	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.005	0.995	0.000
C67.1 Dome of bladder	0.005	0.995	0.000
Chapter XX External causes of morbidity and mortality	0.005	0.995	0.000
I86.1 Scrotal varices	0.005	0.995	0.000
G91.8 Other hydrocephalus	0.005	0.995	0.000
G96 Other disorders of central nervous system	0.005	0.995	0.000
Z48.0 Attention to surgical dressings and sutures	0.005	0.995	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.005	0.995	0.000
G93.2 Benign intracranial hypertension	0.005	0.995	0.000
G93 Other disorders of brain	0.005	0.995	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.005	0.995	0.000
W50-W64 Exposure to animate mechanical forces	0.005	0.995	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.005	0.995	0.000
G96.8 Other specified disorders of central nervous system	0.005	0.995	0.000
G90.2 Horner's syndrome	0.005	0.995	0.000
G91.0 Communicating hydrocephalus	0.005	0.995	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.005	0.995	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.005	0.995	0.000
J33 Nasal polyp	0.005	0.995	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.995	0.005
D23.5 Skin of trunk	0.005	0.995	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.005	0.995	0.000
G93.6 Cerebral oedema	0.005	0.995	0.000
G93.5 Compression of brain	0.004	0.995	0.000
G97.8 Other postprocedural disorders of nervous system	0.004	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.004	0.995	0.000
G92 Toxic encephalopathy	0.004	0.995	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.004	0.996	0.000
M84.28 Delayed union of fracture (Other)	0.004	0.996	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.004	0.996	0.000
M84.26 Delayed union of fracture (Lower leg)	0.004	0.996	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M84.24 Delayed union of fracture (Hand)	0.004	0.996	0.000
M84.23 Delayed union of fracture (Forearm)	0.004	0.996	0.000
M84.22 Delayed union of fracture (Upper arm)	0.004	0.996	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.004	0.996	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.004	0.996	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.004	0.996	0.000
M84.88 Other disorders of continuity of bone (Other)	0.004	0.996	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.004	0.996	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.004	0.996	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.004	0.996	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.004	0.996	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.004	0.996	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.004	0.996	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.004	0.996	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.004	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.996	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.996	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.996	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.996	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.996	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.996	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.996	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.004	0.996	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.004	0.996	0.000
V01-V09 Pedestrian injured in transport accident	0.004	0.996	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
G90.3 Multisystem degeneration	0.004	0.996	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.004	0.996	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.004	0.996	0.000
G93.8 Other specified disorders of brain	0.004	0.996	0.000
X50-X57 Overexertion, travel and privation	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.004	0.996	0.000
X60-X84 Intentional self-harm	0.004	0.996	0.000
S22.3 Fracture of rib	0.004	0.996	0.000
X20-X29 Contact with venomous animals and plants	0.004	0.996	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.004	0.996	0.000
W20-W49 Exposure to inanimate mechanical forces	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.004	0.996	0.000
G90.8 Other disorders of autonomic nervous system	0.004	0.996	0.000
G90.4 Autonomic dysreflexia	0.004	0.996	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.004	0.996	0.000
V20-V29 Motorcycle rider injured in transport accident	0.004	0.996	0.000
V95-V97 Air and space transport accidents	0.004	0.996	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.004	0.996	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.004	0.996	0.000
W51 Striking against or bumped into by another person	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
W50.2 School, other institution and public administrative area	0.004	0.996	0.000
Y35-Y36 Legal intervention and operations of war	0.004	0.996	0.000
Y10-Y34 Event of undetermined intent	0.004	0.996	0.000
X85-X99 Assault	0.004	0.996	0.000
X30-X39 Exposure to forces of nature	0.004	0.996	0.000
X00-X09 Exposure to smoke, fire and flames	0.004	0.996	0.000
W65-W74 Accidental drowning and submersion	0.004	0.996	0.000
V90-V94 Water transport accidents	0.004	0.996	0.000
V70-V79 Bus occupant injured in transport accident	0.004	0.996	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.004	0.996	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.004	0.996	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.004	0.996	0.000
S22.1 Multiple fractures of thoracic spine	0.004	0.996	0.000
W75-W84 Other accidental threats to breathing	0.004	0.996	0.000
G96.9 Disorder of central nervous system, unspecified	0.004	0.996	0.000
H93.1 Tinnitus	0.000	0.996	0.004
Y89.9 Sequelae of unspecified external cause	0.004	0.996	0.000
Y89 Sequelae of other external causes	0.004	0.996	0.000
S22.4 Multiple fractures of ribs	0.004	0.996	0.000
X10-X19 Contact with heat and hot substances	0.004	0.996	0.000
T18.1 Foreign body in oesophagus	0.000	0.996	0.004
Y00-Y09 Assault	0.004	0.996	0.000
V40-V49 Car occupant injured in transport accident	0.004	0.996	0.000
V09 Pedestrian injured in other and unspecified transport accidents	0.004	0.996	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.004	0.996	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.004	0.996	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.004	0.996	0.000
G93.7 Reye's syndrome	0.004	0.996	0.000
V98-V99 Other and unspecified transport accidents	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.004	0.996	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.004	0.996	0.000
C67.9 Bladder, unspecified	0.004	0.996	0.000
S27.3 Other injuries of lung	0.004	0.996	0.000
W55 Bitten or struck by other mammals	0.004	0.996	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.004	0.996	0.000
G93.3 Postviral fatigue syndrome	0.004	0.996	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.004	0.996	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.004	0.996	0.000
W59 Bitten or crushed by other reptiles	0.004	0.996	0.000
W58 Bitten or struck by crocodile or alligator	0.004	0.996	0.000
W56 Contact with marine animal	0.004	0.996	0.000
W54 Bitten or struck by dog	0.004	0.996	0.000
W53 Bitten by rat	0.004	0.996	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.004	0.996	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.004	0.996	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.004	0.996	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.004	0.996	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.996	0.000
W20 Struck by thrown, projected or falling object	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.996	0.003
J33.8 Other polyp of sinus	0.004	0.996	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.004	0.996	0.000
V48 Car occupant injured in noncollision transport accident	0.004	0.996	0.000
S20-S29 Injuries to the thorax	0.004	0.996	0.000
G93.0 Cerebral cysts	0.004	0.996	0.000
Y87.0 Sequelae of intentional self-harm	0.004	0.996	0.000
S22.40 Multiple fractures of ribs (closed)	0.004	0.996	0.000
S22.2 Fracture of sternum	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations