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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1476573
log Bayes Factor = 36.5998
Chromosome 6   position 29,674,648  (GRCh37) Explore rs1476573 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
L40 Psoriasis
0.000 0.007 0.993
L40.5 Arthropathic psoriasis
0.000 0.008 0.992
E10.1 With ketoacidosis
0.000 0.011 0.989
E10.3 With ophthalmic complications
0.000 0.029 0.971
E10.0 With coma
0.000 0.121 0.879
G35 Multiple sclerosis
0.816 0.184 0.000
L40.8 Other psoriasis
0.000 0.205 0.795
E10.2 With renal complications
0.000 0.224 0.776
L40.0 Psoriasis vulgaris
0.000 0.235 0.765
E10.6 With other specified complications
0.000 0.273 0.727
L40.2 Acrodermatitis continua
0.000 0.288 0.712
L40.1 Generalised pustular psoriasis
0.000 0.288 0.712
E10.8 With unspecified complications
0.000 0.321 0.679
E10.7 With multiple complications
0.000 0.346 0.654
E10.4 With neurological complications
0.000 0.348 0.652
L40.3 Pustulosis palmaris et plantaris
0.000 0.360 0.640
L40.4 Guttate psoriasis
0.000 0.361 0.639
E10.5 With peripheral circulatory complications
0.000 0.388 0.612
K90 Intestinal malabsorption
0.000 0.504 0.496
G35-G37 Demyelinating diseases of the central nervous system
0.435 0.565 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.593 0.407
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.407 0.593 0.000
K90.8 Other intestinal malabsorption
0.000 0.634 0.365
I71 Aortic aneurysm and dissection
0.365 0.635 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.644 0.356
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.644 0.356
K90.1 Tropical sprue
0.000 0.644 0.356
G37 Other demyelinating diseases of central nervous system
0.349 0.651 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.335 0.665 0.000
G36 Other acute disseminated demyelination
0.325 0.675 0.000
I71.0 Dissection of aorta [any part]
0.322 0.678 0.000
E83 Disorders of mineral metabolism
0.316 0.684 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.691 0.309
G37.9 Demyelinating disease of central nervous system, unspecified
0.303 0.697 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.279 0.721 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.275 0.725 0.000
E83.3 Disorders of phosphorus metabolism
0.275 0.725 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.262 0.738 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.262 0.738 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.262 0.738 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.255 0.745 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.252 0.748 0.000
G37.5 Concentric sclerosis [Balo]
0.250 0.750 0.000
G37.4 Subacute necrotising myelitis
0.250 0.750 0.000
G37.2 Central pontine myelinolysis
0.250 0.750 0.000
G37.1 Central demyelination of corpus callosum
0.250 0.750 0.000
G37.0 Diffuse sclerosis
0.250 0.750 0.000
G36.0 Neuromyelitis optica [Devic]
0.246 0.754 0.000
L40-L45 Papulosquamous disorders
0.013 0.758 0.229
G36.9 Acute disseminated demyelination, unspecified
0.233 0.767 0.000
G36.8 Other specified acute disseminated demyelination
0.233 0.767 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.233 0.767 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.227 0.773 0.000
E83.8 Other disorders of mineral metabolism
0.227 0.773 0.000
E83.2 Disorders of zinc metabolism
0.227 0.773 0.000
E83.0 Disorders of copper metabolism
0.227 0.773 0.000
E10-E14 Diabetes mellitus
0.001 0.780 0.220
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.207 0.793 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.809 0.191
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.811 0.189
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.814 0.186
L44 Other papulosquamous disorders
0.010 0.826 0.164
L41 Parapsoriasis
0.010 0.826 0.164
L45 Papulosquamous disorders in diseases classified elsewhere
0.010 0.826 0.164
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.830 0.170
L42 Pityriasis rosea
0.009 0.830 0.161
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.831 0.169
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.832 0.168
E14 Unspecified diabetes mellitus
0.000 0.833 0.167
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.838 0.162
E12 Malnutrition-related diabetes mellitus
0.001 0.842 0.158
E89.0 Postprocedural hypothyroidism
0.151 0.849 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.143 0.857 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.859 0.141
E13 Other specified diabetes mellitus
0.001 0.859 0.140
E14.3 With ophthalmic complications
0.000 0.861 0.139
E14.4 With neurological complications
0.000 0.866 0.134
E14.5 With peripheral circulatory complications
0.000 0.868 0.132
E83.5 Disorders of calcium metabolism
0.130 0.870 0.000
E89.2 Postprocedural hypoparathyroidism
0.128 0.872 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.126 0.874 0.000
L41.9 Parapsoriasis, unspecified
0.007 0.875 0.118
L41.8 Other parapsoriasis
0.007 0.875 0.118
L41.5 Retiform parapsoriasis
0.007 0.875 0.118
L41.4 Large plaque parapsoriasis
0.007 0.875 0.118
L41.3 Small plaque parapsoriasis
0.007 0.875 0.118
L41.2 Lymphomatoid papulosis
0.007 0.875 0.118
L41.1 Pityriasis lichenoides chronica
0.007 0.875 0.118
L41.0 Pityriasis lichenoides et varioliformis acuta
0.007 0.875 0.118
L44.9 Papulosquamous disorder, unspecified
0.007 0.875 0.118
L44.8 Other specified papulosquamous disorders
0.007 0.875 0.118
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.007 0.875 0.118
L44.3 Lichen ruber moniliformis
0.007 0.875 0.118
L44.2 Lichen striatus
0.007 0.875 0.118
L44.1 Lichen nitidus
0.007 0.875 0.118
L44.0 Pityriasis rubra pilaris
0.007 0.875 0.118
E14.1 With ketoacidosis
0.000 0.878 0.122
E14.7 With multiple complications
0.000 0.880 0.120
E14.2 Withrenal complications
0.000 0.880 0.120
E14.0 With coma
0.000 0.880 0.120
E14.8 With unspecified complications
0.000 0.881 0.119
L43 Lichen planus
0.044 0.883 0.073
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.886 0.114
E89.4 Postprocedural ovarian failure
0.114 0.886 0.000
E12.9 Without complications
0.001 0.886 0.113
E12.8 With unspecified complications
0.001 0.886 0.113
E12.7 With multiple complications
0.001 0.886 0.113
E12.6 With other specified complications
0.001 0.886 0.113
E12.5 With peripheral circulatory complications
0.001 0.886 0.113
E12.4 With neurological complications
0.001 0.886 0.113
E12.3 With ophthalmic complications
0.001 0.886 0.113
E12.2 With renal complications
0.001 0.886 0.113
E12.1 With ketoacidosis
0.001 0.886 0.113
E12.0 With coma
0.001 0.886 0.113
E70-E90 Metabolic disorders
0.111 0.888 0.001
E14.6 With other specified complications
0.000 0.888 0.111
E89.1 Postprocedural hypoinsulinaemia
0.110 0.890 0.000
E13.3 With ophthalmic complications
0.000 0.897 0.103
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.102 0.897 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.102 0.897 0.000
E89.5 Postprocedural testicular hypofunction
0.102 0.897 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.898 0.102
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.898 0.102
E13.8 With unspecified complications
0.001 0.899 0.101
E13.7 With multiple complications
0.001 0.899 0.101
E13.6 With other specified complications
0.001 0.899 0.101
E13.5 With peripheral circulatory complications
0.001 0.899 0.101
E13.4 With neurological complications
0.001 0.899 0.101
E13.2 With renal complications
0.001 0.899 0.101
E13.1 With ketoacidosis
0.001 0.899 0.101
E13.0 With coma
0.001 0.899 0.101
E83.4 Disorders of magnesium metabolism
0.092 0.908 0.000
M06 Other rheumatoid arthritis
0.000 0.914 0.086
E84 Cystic fibrosis
0.085 0.915 0.001
L43.3 Subacute (active) lichen planus
0.032 0.916 0.053
L43.2 Lichenoid drug reaction
0.032 0.916 0.053
L43.1 Bullous lichen planus
0.032 0.916 0.053
L43.0 Hypertrophic lichen planus
0.032 0.916 0.053
E74 Other disorders of carbohydrate metabolism
0.083 0.917 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.082 0.918 0.001
E13.9 Without complications
0.000 0.920 0.080
E77 Disorders of glycoprotein metabolism
0.080 0.920 0.001
E76 Disorders of glycosaminoglycan metabolism
0.080 0.920 0.001
E72 Other disorders of amino-acid metabolism
0.080 0.920 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.080 0.920 0.001
E70 Disorders of aromatic amino-acid metabolism
0.080 0.920 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.080 0.920 0.001
L43.9 Lichen planus, unspecified
0.074 0.924 0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.924 0.076
L43.8 Other lichen planus
0.034 0.924 0.041
E79 Disorders of purine and pyrimidine metabolism
0.074 0.925 0.001
N13 Obstructive and reflux uropathy
0.000 0.927 0.073
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.927 0.073
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.929 0.071
E73 Lactose intolerance
0.068 0.931 0.001
M06.3 Rheumatoid nodule
0.000 0.933 0.067
E84.9 Cystic fibrosis, unspecified
0.066 0.933 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.064 0.935 0.001
E74.3 Other disorders of intestinal carbohydrate absorption
0.062 0.938 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.938 0.061
M06.2 Rheumatoid bursitis
0.000 0.938 0.061
M06.1 Adult-onset Still's disease
0.000 0.938 0.061
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.938 0.061
E84.8 Cystic fibrosis with other manifestations
0.061 0.938 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.061 0.938 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.061 0.938 0.001
E75.5 Other lipid storage disorders
0.061 0.939 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.939 0.061
E74.9 Disorder of carbohydrate metabolism, unspecified
0.059 0.940 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.059 0.940 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.059 0.940 0.001
E74.2 Disorders of galactose metabolism
0.059 0.940 0.001
E74.1 Disorders of fructose metabolism
0.059 0.940 0.001
E74.0 Glycogen storage disease
0.059 0.940 0.001
E75.6 Lipid storage disorder, unspecified
0.059 0.941 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.059 0.941 0.001
E75.3 Sphingolipidosis, unspecified
0.059 0.941 0.001
E75.2 Other sphingolipidosis
0.059 0.941 0.001
E75.1 Other gangliosidosis
0.059 0.941 0.001
E75.0 GM2 gangliosidosis
0.059 0.941 0.001
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.942 0.058
M06.4 Inflammatory polyarthropathy
0.000 0.942 0.058
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.057 0.942 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.057 0.942 0.001
E70.3 Albinism
0.057 0.942 0.001
E70.2 Disorders of tyrosine metabolism
0.057 0.942 0.001
E70.1 Other hyperphenylalaninaemias
0.057 0.942 0.001
E70.0 Classical phenylketonuria
0.057 0.942 0.001
E71.3 Disorders of fatty-acid metabolism
0.057 0.942 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.057 0.942 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.057 0.942 0.001
E71.0 Maple-syrup-urine disease
0.057 0.942 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.057 0.942 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.057 0.942 0.001
E72.5 Disorders of glycine metabolism
0.057 0.942 0.001
E72.4 Disorders of ornithine metabolism
0.057 0.942 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.057 0.942 0.001
E72.2 Disorders of urea cycle metabolism
0.057 0.942 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.057 0.942 0.001
E72.0 Disorders of amino-acid transport
0.057 0.942 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.057 0.942 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.057 0.942 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.057 0.942 0.001
E76.2 Other mucopolysaccharidoses
0.057 0.942 0.001
E76.1 Mucopolysaccharidosis, type II
0.057 0.942 0.001
E76.0 Mucopolysaccharidosis, type I
0.057 0.942 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.057 0.942 0.001
E77.8 Other disorders of glycoprotein metabolism
0.057 0.942 0.001
E77.1 Defects in glycoprotein degradation
0.057 0.942 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.057 0.942 0.001
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.943 0.057
E14.9 Without complications
0.000 0.945 0.055
I70-I79 Diseases of arteries, arterioles and capillaries
0.055 0.945 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.053 0.946 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.053 0.946 0.001
E79.1 Lesch-Nyhan syndrome
0.053 0.946 0.001
E80.1 Porphyria cutanea tarda
0.052 0.947 0.000
I72 Other aneurysm
0.052 0.948 0.000
I72.4 Aneurysm of artery of lower extremity
0.050 0.950 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.950 0.050
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.950 0.050
E73.8 Other lactose intolerance
0.049 0.950 0.001
E73.1 Secondary lactase deficiency
0.049 0.950 0.001
E73.0 Congenital lactase deficiency
0.049 0.950 0.001
E80.6 Other disorders of bilirubin metabolism
0.049 0.951 0.000
E89.3 Postprocedural hypopituitarism
0.048 0.951 0.001
E88 Other metabolic disorders
0.048 0.951 0.001
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.951 0.048
M06.38 Rheumatoid nodule (Other)
0.000 0.951 0.048
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.951 0.048
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.951 0.048
M06.33 Rheumatoid nodule (Forearm)
0.000 0.951 0.048
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.951 0.048
I70 Atherosclerosis
0.048 0.952 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.047 0.952 0.001
E80.7 Disorder of bilirubin metabolism, unspecified
0.046 0.953 0.001
E80.5 Crigler-Najjar syndrome
0.046 0.953 0.001
E80.3 Defects of catalase and peroxydase
0.046 0.953 0.001
E80.0 Hereditary erythropoietic porphyria
0.046 0.953 0.001
Chapter IV Endocrine, nutritional and metabolic diseases
0.008 0.954 0.037
M06.0 Seronegative rheumatoid arthritis
0.000 0.955 0.045
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.955 0.045
E80.2 Other porphyria
0.044 0.955 0.001
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.956 0.044
M06.18 Adult-onset Still's disease (Other)
0.000 0.956 0.044
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.956 0.044
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.956 0.044
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.956 0.044
M06.14 Adult-onset Still's disease (Hand)
0.000 0.956 0.044
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.956 0.044
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.956 0.044
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.956 0.044
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.956 0.044
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.956 0.044
M06.28 Rheumatoid bursitis (Other)
0.000 0.956 0.044
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.956 0.044
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.956 0.044
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.956 0.044
M06.24 Rheumatoid bursitis (Hand)
0.000 0.956 0.044
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.956 0.044
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.956 0.044
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.956 0.044
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.956 0.044
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.956 0.044
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.956 0.044
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.956 0.044
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.956 0.044
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.956 0.044
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.956 0.044
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.956 0.044
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.956 0.044
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.956 0.044
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.956 0.044
I70.2 Atherosclerosis of arteries of the extremities
0.044 0.956 0.000
N13.6 Pyonephrosis
0.000 0.957 0.043
E11 Non-insulin-dependent diabetes mellitus
0.000 0.957 0.043
K90-K93 Other diseases of the digestive system
0.000 0.958 0.042
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.958 0.042
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.958 0.042
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.958 0.042
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.958 0.042
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.958 0.042
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.958 0.042
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.958 0.042
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.958 0.042
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.004 0.959 0.037
E85 Amyloidosis
0.040 0.959 0.001
M06.34 Rheumatoid nodule (Hand)
0.000 0.959 0.040
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.040 0.960 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.960 0.040
I72.0 Aneurysm of carotid artery
0.039 0.961 0.000
I70.8 Atherosclerosis of other arteries
0.039 0.961 0.000
I72.9 Aneurysm of unspecified site
0.039 0.961 0.000
E73.9 Lactose intolerance, unspecified
0.038 0.962 0.001
E16 Other disorders of pancreatic internal secretion
0.001 0.962 0.037
E11.0 With coma
0.000 0.962 0.038
I72.6 Aneurysm and dissection of vertebral artery
0.037 0.963 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.037 0.963 0.000
I72.2 Aneurysm of renal artery
0.037 0.963 0.000
E88.3 Tumour lysis syndrome
0.036 0.963 0.001
I72.1 Aneurysm of artery of upper extremity
0.037 0.963 0.000
E11.6 With other specified complications
0.000 0.964 0.036
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.964 0.036
E88.9 Metabolic disorder, unspecified
0.035 0.964 0.001
N13.3 Other and unspecified hydronephrosis
0.000 0.964 0.036
E16.2 Hypoglycaemia, unspecified
0.000 0.965 0.035
E88.1 Lipodystrophy, not elsewhere classified
0.034 0.965 0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.035 0.965 0.000
I72.3 Aneurysm of iliac artery
0.035 0.965 0.000
I70.9 Generalised and unspecified atherosclerosis
0.035 0.965 0.000
I70.1 Atherosclerosis of renal artery
0.034 0.965 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.966 0.034
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.966 0.034
M07.3 Other psoriatic arthropathies
0.000 0.966 0.034
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.966 0.034
I72.8 Aneurysm of other specified arteries
0.034 0.966 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.034 0.966 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.966 0.033
M05-M14 Inflammatory polyarthropathies
0.000 0.966 0.034
M07 Psoriatic and enteropathic arthropathies
0.000 0.967 0.033
E88.8 Other specified metabolic disorders
0.032 0.967 0.001
E11.8 With unspecified complications
0.000 0.967 0.033
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.967 0.033
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.967 0.033
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.967 0.033
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.967 0.033
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.967 0.033
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.967 0.033
I70.80 Atherosclerosis of other arteries (without gangrene)
0.032 0.968 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.968 0.032
E20-E35 Disorders of other endocrine glands
0.000 0.968 0.032
E16.1 Other hypoglycaemia
0.000 0.968 0.031
E88.2 Lipomatosis, not elsewhere classified
0.031 0.968 0.001
E11.7 With multiple complications
0.000 0.969 0.031
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.969 0.030
E50-E64 Other nutritional deficiencies
0.003 0.970 0.027
C73 Malignant neoplasm of thyroid gland
0.030 0.970 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.970 0.030
E15 Nondiabetic hypoglycaemic coma
0.003 0.970 0.027
E85.2 Heredofamilial amyloidosis, unspecified
0.028 0.971 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.028 0.971 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.028 0.971 0.001
E85.8 Other amyloidosis
0.028 0.971 0.001
I70.0 Atherosclerosis of aorta
0.029 0.971 0.000
E85.3 Secondary systemic amyloidosis
0.027 0.972 0.001
I70.81 Atherosclerosis of other arteries (with gangrene)
0.028 0.972 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.972 0.028
M12 Other specific arthropathies
0.000 0.972 0.028
E16.9 Disorder of pancreatic internal secretion, unspecified
0.001 0.972 0.027
E16.8 Other specified disorders of pancreatic internal secretion
0.001 0.972 0.027
E16.4 Abnormal secretion of gastrin
0.001 0.972 0.027
E16.3 Increased secretion of glucagon
0.001 0.972 0.027
E11.2 With renal complications
0.000 0.972 0.027
E24 Cushing's syndrome
0.000 0.973 0.027
E11.1 With ketoacidosis
0.000 0.973 0.027
E61 Deficiency of other nutrient elements
0.001 0.973 0.026
N13.8 Other obstructive and reflux uropathy
0.000 0.974 0.026
E40-E46 Malnutrition
0.007 0.974 0.020
I74 Arterial embolism and thrombosis
0.026 0.974 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.974 0.026
E21.0 Primary hyperparathyroidism
0.000 0.974 0.026
E11.4 With neurological complications
0.000 0.975 0.025
E28 Ovarian dysfunction
0.000 0.975 0.025
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.025 0.975 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.025 0.975 0.000
M11 Other crystal arthropathies
0.000 0.975 0.025
N13.4 Hydroureter
0.000 0.975 0.025
E21.4 Other specified disorders of parathyroid gland
0.000 0.975 0.025
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.025 0.975 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.975 0.025
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.975 0.025
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.975 0.025
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.975 0.025
I70.10 Atherosclerosis of renal artery (without gangrene)
0.024 0.975 0.000
N10-N16 Renal tubulo-interstitial diseases
0.000 0.975 0.025
E61.1 Iron deficiency
0.000 0.975 0.024
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.024 0.976 0.000
I79.1 Aortitis in diseases classified elsewhere
0.024 0.976 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.024 0.976 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.976 0.024
M07.5 Arthropathy in ulcerative colitis
0.000 0.976 0.024
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.976 0.024
M07.2 Psoriatic spondylitis
0.000 0.976 0.024
M07.1 Arthritis mutilans
0.000 0.976 0.024
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.976 0.024
M07.6 Other enteropathic arthropathies
0.000 0.976 0.024
E29 Testicular dysfunction
0.000 0.976 0.023
M08 Juvenile arthritis
0.000 0.976 0.023
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.976 0.023
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.977 0.023
N11 Chronic tubulo-interstitial nephritis
0.000 0.977 0.023
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.977 0.023
E32 Diseases of thymus
0.000 0.977 0.023
E31 Polyglandular dysfunction
0.000 0.977 0.023
E30 Disorders of puberty, not elsewhere classified
0.000 0.977 0.023
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.977 0.023
E25 Adrenogenital disorders
0.000 0.977 0.022
E24.2 Drug-induced Cushing's syndrome
0.000 0.977 0.022
E24.0 Pituitary-dependent Cushing's disease
0.000 0.978 0.022
E21.2 Other hyperparathyroidism
0.000 0.978 0.022
M12.3 Palindromic rheumatism
0.000 0.978 0.022
I78 Diseases of capillaries
0.022 0.978 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.978 0.022
K93.1 Megacolon in Chagas' disease
0.000 0.978 0.022
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.978 0.022
E28.2 Polycystic ovarian syndrome
0.000 0.978 0.022
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.000 0.978 0.022
I74.0 Embolism and thrombosis of abdominal aorta
0.022 0.978 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.002 0.978 0.020
E63 Other nutritional deficiencies
0.002 0.978 0.020
E56 Other vitamin deficiencies
0.002 0.978 0.020
E50 Vitamin A deficiency
0.002 0.978 0.020
E60 Dietary zinc deficiency
0.002 0.978 0.020
E59 Dietary selenium deficiency
0.002 0.978 0.020
E54 Ascorbic acid deficiency
0.002 0.978 0.020
E52 Niacin deficiency [pellagra]
0.002 0.978 0.020
E51 Thiamine deficiency
0.002 0.978 0.020
M12.2 Villonodular synovitis (pigmented)
0.000 0.978 0.022
I77 Other disorders of arteries and arterioles
0.022 0.978 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.978 0.021
M14 Arthropathies in other diseases classified elsewhere
0.000 0.979 0.021
I70.01 Atherosclerosis of aorta (with gangrene)
0.021 0.979 0.000
I74.8 Embolism and thrombosis of other arteries
0.021 0.979 0.000
E61.2 Magnesium deficiency
0.001 0.979 0.020
E11.5 With peripheral circulatory complications
0.000 0.979 0.020
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.020 0.980 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.980 0.020
I74.9 Embolism and thrombosis of unspecified artery
0.020 0.980 0.000
E20 Hypoparathyroidism
0.000 0.980 0.020
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.980 0.020
M12.5 Traumatic arthropathy
0.000 0.980 0.020
M12.4 Intermittent hydrarthrosis
0.000 0.980 0.020
M12.1 Kaschin-Beck disease
0.000 0.980 0.020
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.980 0.020
E24.8 Other Cushing's syndrome
0.000 0.980 0.020
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.980 0.020
E24.3 Ectopic ACTH syndrome
0.000 0.980 0.020
E24.1 Nelson's syndrome
0.000 0.980 0.020
I77.2 Rupture of artery
0.020 0.980 0.000
E61.9 Deficiency of nutrient element, unspecified
0.001 0.981 0.019
E61.8 Deficiency of other specified nutrient elements
0.001 0.981 0.019
E61.7 Deficiency of multiple nutrient elements
0.001 0.981 0.019
E61.6 Vanadium deficiency
0.001 0.981 0.019
E61.5 Molybdenum deficiency
0.001 0.981 0.019
E61.4 Chromium deficiency
0.001 0.981 0.019
E61.3 Manganese deficiency
0.001 0.981 0.019
E61.0 Copper deficiency
0.001 0.981 0.019
E58 Dietary calcium deficiency
0.002 0.981 0.017
E86 Volume depletion
0.019 0.981 0.000
M11.2 Other chondrocalcinosis
0.000 0.981 0.019
E44 Protein-energy malnutrition of moderate and mild degree
0.005 0.981 0.014
E45 Retarded development following protein-energy malnutrition
0.005 0.981 0.014
E43 Unspecified severe protein-energy malnutrition
0.005 0.981 0.014
E42 Marasmic kwashiorkor
0.005 0.981 0.014
E41 Nutritional marasmus
0.005 0.981 0.014
E40 Kwashiorkor
0.005 0.981 0.014
E85.4 Organ-limited amyloidosis
0.018 0.981 0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.019 0.981 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.000 0.981 0.019
E55 Vitamin D deficiency
0.001 0.981 0.017
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.018 0.981 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.982 0.018
E28.8 Other ovarian dysfunction
0.000 0.982 0.018
E28.1 Androgen excess
0.000 0.982 0.018
E28.0 Oestrogen excess
0.000 0.982 0.018
E34 Other endocrine disorders
0.000 0.982 0.018
M11.1 Familial chondrocalcinosis
0.000 0.982 0.018
M11.0 Hydroxyapatite deposition disease
0.000 0.982 0.018
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.018 0.982 0.000
N11.1 Chronic obstructive pyelonephritis
0.000 0.982 0.018
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.982 0.018
M11.9 Crystal arthropathy, unspecified
0.000 0.982 0.018
M11.8 Other specified crystal arthropathies
0.000 0.982 0.018
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.000 0.982 0.018
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.982 0.018
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.000 0.982 0.018
I77.0 Arteriovenous fistula, acquired
0.018 0.982 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.982 0.018
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.982 0.017
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.982 0.017
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.982 0.017
M09.0 Juvenile arthritis in psoriasis
0.000 0.982 0.017
E85.9 Amyloidosis, unspecified
0.016 0.982 0.001
E22 Hyperfunction of pituitary gland
0.000 0.982 0.017
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.982 0.017
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.982 0.017
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.982 0.017
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.982 0.017
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.982 0.017
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.982 0.017
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.982 0.017
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.982 0.017
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.982 0.017
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.982 0.017
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.982 0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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