TreeWAS – Variant ID: rs1476587

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G56.0 Carpal tunnel syndrome	0.043	0.957	0.000
G57.6 Lesion of plantar nerve	0.039	0.961	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.037	0.963	0.000
G57 Mononeuropathies of lower limb	0.036	0.964	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.036	0.964	0.000
T39.1 4-Aminophenol derivatives	0.035	0.965	0.000
T39.0 Salicylates	0.035	0.965	0.000
G56 Mononeuropathies of upper limb	0.034	0.966	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.033	0.967	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.029	0.971	0.000
G57.3 Lesion of lateral popliteal nerve	0.029	0.971	0.000
G57.1 Meralgia paraesthetica	0.029	0.971	0.000
G57.8 Other mononeuropathies of lower limb	0.029	0.971	0.000
G57.5 Tarsal tunnel syndrome	0.028	0.972	0.000
T39.4 Antirheumatics, not elsewhere classified	0.027	0.973	0.000
T39.2 Pyrazolone derivatives	0.027	0.973	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.026	0.974	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.026	0.974	0.000
G57.4 Lesion of medial popliteal nerve	0.026	0.974	0.000
G57.2 Lesion of femoral nerve	0.026	0.974	0.000
G57.0 Lesion of sciatic nerve	0.026	0.974	0.000
G56.1 Other lesions of median nerve	0.025	0.975	0.000
G56.4 Causalgia	0.024	0.976	0.000
G56.2 Lesion of ulnar nerve	0.024	0.976	0.000
G58 Other mononeuropathies	0.024	0.976	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.024	0.976	0.000
G50 Disorders of trigeminal nerve	0.023	0.977	0.000
G56.8 Other mononeuropathies of upper limb	0.023	0.977	0.000
G52 Disorders of other cranial nerves	0.023	0.977	0.000
G56.3 Lesion of radial nerve	0.023	0.977	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.020	0.980	0.000
G54 Nerve root and plexus disorders	0.020	0.980	0.000
G58.9 Mononeuropathy, unspecified	0.019	0.981	0.000
G50.0 Trigeminal neuralgia	0.018	0.982	0.000
G58.8 Other specified mononeuropathies	0.018	0.982	0.000
G52.9 Cranial nerve disorder, unspecified	0.018	0.982	0.000
G58.7 Mononeuritis multiplex	0.018	0.982	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.018	0.982	0.000
G58.0 Intercostal neuropathy	0.017	0.983	0.000
G50.1 Atypical facial pain	0.017	0.983	0.000
G50.8 Other disorders of trigeminal nerve	0.017	0.983	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.017	0.983	0.000
G52.7 Disorders of multiple cranial nerves	0.016	0.983	0.000
G52.3 Disorders of hypoglossal nerve	0.016	0.983	0.000
G52.2 Disorders of vagus nerve	0.016	0.983	0.000
G52.1 Disorders of glossopharyngeal nerve	0.016	0.983	0.000
G52.0 Disorders of olfactory nerve	0.016	0.983	0.000
G52.8 Disorders of other specified cranial nerves	0.016	0.983	0.000
G54.0 Brachial plexus disorders	0.016	0.983	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.016	0.984	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.014	0.985	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.014	0.985	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.014	0.985	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.014	0.985	0.000
G54.8 Other nerve root and plexus disorders	0.014	0.986	0.000
G54.7 Phantom limb syndrome without pain	0.014	0.986	0.000
G54.6 Phantom limb syndrome with pain	0.014	0.986	0.000
G54.5 Neuralgic amyotrophy	0.014	0.986	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.014	0.986	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.014	0.986	0.000
G54.1 Lumbosacral plexus disorders	0.014	0.986	0.000
G51 Facial nerve disorders	0.014	0.986	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.013	0.986	0.000
G53.0 Postzoster neuralgia	0.013	0.987	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.013	0.987	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.013	0.987	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.012	0.988	0.000
G51.4 Facial myokymia	0.010	0.990	0.000
G51.2 Melkersson's syndrome	0.010	0.990	0.000
G51.1 Geniculate ganglionitis	0.010	0.990	0.000
Y95 Nosocomial condition	0.010	0.990	0.000
G51.8 Other disorders of facial nerve	0.010	0.990	0.000
G51.3 Clonic hemifacial spasm	0.009	0.990	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.009	0.991	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.009	0.991	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.009	0.991	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.991	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.009	0.991	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.009	0.991	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.009	0.991	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.009	0.991	0.000
G51.0 Bell's palsy	0.008	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
G51.9 Disorder of facial nerve, unspecified	0.008	0.992	0.000
G59.0 Diabetic mononeuropathy	0.007	0.992	0.000
T36 Poisoning by systemic antibiotics	0.008	0.992	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.007	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.007	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.007	0.993	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.993	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.007	0.993	0.000
T36.0 Penicillins	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.993	0.000
J32.9 Chronic sinusitis, unspecified	0.007	0.993	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.993	0.000
T50.8 Diagnostic agents	0.006	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
T50.5 Appetite depressants	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.006	0.994	0.000
K81.9 Cholecystitis, unspecified	0.000	0.994	0.006
T40.4 Other synthetic narcotics	0.006	0.994	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.006	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
K81.0 Acute cholecystitis	0.000	0.994	0.006
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
T36.8 Other systemic antibiotics	0.006	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
T36.6 Rifamycins	0.006	0.994	0.000
T36.5 Aminoglycosides	0.006	0.994	0.000
T36.4 Tetracyclines	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T36.2 Chloramphenicol group	0.006	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
M80 Osteoporosis with pathological fracture	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T37.1 Antimycobacterial drugs	0.006	0.994	0.000
T37.0 Sulphonamides	0.006	0.994	0.000
J32 Chronic sinusitis	0.006	0.994	0.000
K81 Cholecystitis	0.000	0.994	0.006
J32.0 Chronic maxillary sinusitis	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.005	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.005	0.995	0.000
E04.1 Non-toxic single thyroid nodule	0.005	0.995	0.000
I42.0 Dilated cardiomyopathy	0.005	0.995	0.000
J32.1 Chronic frontal sinusitis	0.005	0.995	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.005	0.995	0.000
K81.1 Chronic cholecystitis	0.000	0.995	0.005
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.005	0.995	0.000
J32.4 Chronic pansinusitis	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
J32.2 Chronic ethmoidal sinusitis	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.995	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.005	0.995	0.000
M80.8 Other osteoporosis with pathological fracture	0.004	0.996	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.004	0.996	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.004	0.996	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.004	0.996	0.000
I42 Cardiomyopathy	0.004	0.996	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.004	0.996	0.000
J32.3 Chronic sphenoidal sinusitis	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
K81.8 Other cholecystitis	0.000	0.996	0.004
G55.2 Nerve root and plexus compressions in spondylosis	0.004	0.996	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.004	0.996	0.000
I42.8 Other cardiomyopathies	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.996	0.004
I42.6 Alcoholic cardiomyopathy	0.004	0.996	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.996	0.004
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.004	0.996	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.004	0.996	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.004	0.996	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.004	0.996	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.004	0.996	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.004	0.996	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.004	0.996	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
Q21.1 Atrial septal defect	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
R17 Unspecified jaundice	0.000	0.996	0.004
T40.2 Other opioids	0.004	0.996	0.000
J32.8 Other chronic sinusitis	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.996	0.000
I42.2 Other hypertrophic cardiomyopathy	0.004	0.996	0.000
T45.5 Anticoagulants	0.003	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
D68.8 Other specified coagulation defects	0.000	0.996	0.004
B07 Viral warts	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.996	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.003	0.996	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.003	0.997	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.003	0.997	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.003	0.997	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
I42.4 Endocardial fibroelastosis	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
D68 Other coagulation defects	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.003	0.997	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
N19 Unspecified renal failure	0.000	0.997	0.003
Z97 Presence of other devices	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q35.9 Cleft palate, unspecified	0.003	0.997	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.003	0.997	0.000
Y98 Lifestyle-related condition	0.003	0.997	0.000
Y97 Environmental-pollution-related condition	0.003	0.997	0.000
Y96 Work-related condition	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
I84.1 Internal haemorrhoids with other complications	0.003	0.997	0.000
Q24.6 Congenital heart block	0.002	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
Q24.0 Dextrocardia	0.002	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q04 Other congenital malformations of brain	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.997	0.000
Q27.4 Congenital phlebectasia	0.002	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.002
Q07 Other congenital malformations of nervous system	0.002	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.997	0.000
D68.5 Primary Thrombophilia	0.000	0.997	0.002
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.997	0.000
Q22.5 Ebstein's anomaly	0.002	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.997	0.000
Q22.0 Pulmonary valve atresia	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
E04.8 Other specified non-toxic goitre	0.002	0.997	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.003	0.997	0.000
Q96 Turner's syndrome	0.002	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
M79.62 Pain in limb (Upper arm)	0.002	0.998	0.000
Z97.3 Presence of spectacles and contact lenses	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations