TreeWAS – Variant ID: rs148200221

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J43.9 Emphysema, unspecified	0.000	0.645	0.355
J43 Emphysema	0.000	0.656	0.344
J44 Other chronic obstructive pulmonary disease	0.000	0.662	0.338
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.663	0.337
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.671	0.329
J40-J47 Chronic lower respiratory diseases	0.000	0.684	0.316
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.686	0.314
J43.2 Centrilobular emphysema	0.000	0.699	0.301
J43.8 Other emphysema	0.000	0.720	0.280
J42 Unspecified chronic bronchitis	0.000	0.724	0.276
J43.1 Panlobular emphysema	0.000	0.753	0.247
J43.0 MacLeod's syndrome	0.000	0.753	0.247
J41 Simple and mucopurulent chronic bronchitis	0.000	0.787	0.212
J46 Status asthmaticus	0.000	0.815	0.184
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.847	0.152
J41.1 Mucopurulent chronic bronchitis	0.000	0.847	0.152
J41.0 Simple chronic bronchitis	0.000	0.861	0.139
J40 Bronchitis, not specified as acute or chronic	0.000	0.871	0.129
J45 Asthma	0.000	0.894	0.106
J45.0 Predominantly allergic asthma	0.000	0.923	0.077
J45.1 Nonallergic asthma	0.000	0.928	0.072
J45.8 Mixed asthma	0.000	0.934	0.066
J47 Bronchiectasis	0.000	0.958	0.042
Y42.5 Other oestrogens and progestogens	0.000	0.966	0.034
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.973	0.026
K65 Peritonitis	0.000	0.976	0.024
K65.8 Other peritonitis	0.000	0.977	0.023
K65.0 Acute peritonitis	0.000	0.977	0.023
M54.16 Radiculopathy (Lumbar region)	0.000	0.978	0.022
S82.20 Fracture of shaft of tibia (closed)	0.021	0.979	0.000
K66.8 Other specified disorders of peritoneum	0.000	0.979	0.021
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.979	0.021
K66 Other disorders of peritoneum	0.000	0.980	0.020
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.980	0.020
K65.9 Peritonitis, unspecified	0.000	0.980	0.020
K65-K67 Diseases of peritoneum	0.000	0.980	0.020
Y42.7 Androgens and anabolic congeners	0.000	0.981	0.019
R60.0 Localised oedema	0.000	0.982	0.018
K66.1 Haemoperitoneum	0.000	0.982	0.018
I35.9 Aortic valve disorder, unspecified	0.000	0.982	0.018
I35.1 Aortic (valve) insufficiency	0.000	0.983	0.017
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.983	0.017
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.983	0.017
K66.9 Disorder of peritoneum, unspecified	0.000	0.983	0.017
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.984	0.016
Y42.2 Antithyroid drugs	0.000	0.984	0.016
O32.0 Maternal care for unstable lie	0.000	0.984	0.016
I35 Nonrheumatic aortic valve disorders	0.000	0.984	0.016
O32.4 Maternal care for high head at term	0.000	0.984	0.016
Y42.9 Other and unspecified hormone antagonists	0.000	0.985	0.015
Y42.4 Oral contraceptives	0.000	0.985	0.015
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.985	0.015
Y42.1 Thyroid hormones and substitutes	0.000	0.985	0.015
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.985	0.015
O32.2 Maternal care for transverse and oblique lie	0.000	0.986	0.014
L93.0 Discoid lupus erythematosus	0.000	0.986	0.013
O32.6 Maternal care for compound presentation	0.000	0.987	0.013
O32.8 Maternal care for other malpresentation of foetus	0.000	0.988	0.012
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.989	0.011
S82.2 Fracture of shaft of tibia	0.011	0.989	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.989	0.011
K67.3 Tuberculous peritonitis	0.000	0.989	0.011
K67.2 Syphilitic peritonitis	0.000	0.989	0.011
K67.1 Gonococcal peritonitis	0.000	0.989	0.011
K67.0 Chlamydial peritonitis	0.000	0.989	0.011
O32.3 Maternal care for face, brow and chin presentation	0.000	0.989	0.010
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.990	0.009
O32.1 Maternal care for breech presentation	0.000	0.991	0.009
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.009	0.991	0.000
S20 Superficial injury of thorax	0.009	0.991	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.008	0.992	0.000
S27.0 Traumatic pneumothorax	0.008	0.992	0.000
S82.21 Fracture of shaft of tibia (open)	0.008	0.992	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.992	0.008
S27 Injury of other and unspecified intrathoracic organs	0.008	0.992	0.000
S20.1 Other and unspecified superficial injuries of breast	0.007	0.992	0.000
S20.4 Other superficial injuries of back wall of thorax	0.007	0.993	0.000
I35.8 Other aortic valve disorders	0.000	0.993	0.007
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.993	0.007
O47 False labour	0.000	0.993	0.007
S27.3 Other injuries of lung	0.007	0.993	0.000
J92.9 Pleural plaque without asbestos	0.000	0.993	0.007
O47.0 False labour before 37 completed weeks of gestation	0.000	0.993	0.007
S20.2 Contusion of thorax	0.007	0.993	0.000
S20-S29 Injuries to the thorax	0.007	0.993	0.000
S20.0 Contusion of breast	0.007	0.993	0.000
H53.0 Amblyopia ex anopsia	0.007	0.993	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.007	0.993	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.007	0.993	0.000
M54.1 Radiculopathy	0.000	0.993	0.007
S27.1 Traumatic haemothorax	0.007	0.993	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.993	0.006
S20.7 Multiple superficial injuries of thorax	0.006	0.994	0.000
J92 Pleural plaque	0.000	0.994	0.006
J92.0 Pleural plaque with presence of asbestos	0.000	0.994	0.006
L93 Lupus erythematosus	0.000	0.994	0.006
O46.9 Antepartum haemorrhage, unspecified	0.000	0.994	0.006
S22.50 Flail chest (closed)	0.006	0.994	0.000
S27.9 Injury of unspecified intrathoracic organ	0.006	0.994	0.000
S27.7 Multiple injuries of intrathoracic organs	0.006	0.994	0.000
S27.6 Injury of pleura	0.006	0.994	0.000
S27.5 Injury of thoracic trachea	0.006	0.994	0.000
S27.4 Injury of bronchus	0.006	0.994	0.000
K66.0 Peritoneal adhesions	0.000	0.994	0.006
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.994	0.006
S20.3 Other superficial injuries of front wall of thorax	0.006	0.994	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.994	0.006
M54.19 Radiculopathy (Site unspecified)	0.000	0.994	0.006
A40.8 Other streptococcal septicaemia	0.006	0.994	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.006	0.994	0.000
S27.2 Traumatic heamopneumothorax	0.006	0.994	0.000
K62.7 Radiation proctitis	0.006	0.994	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.006	0.994	0.000
S27.8 Injury of other specified intrathoracic organs	0.005	0.994	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.005	0.995	0.000
L93.2 Other local lupus erythematosus	0.000	0.995	0.005
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.005	0.995	0.000
S26 Injury of heart	0.005	0.995	0.000
S25 Injury of blood vessels of thorax	0.005	0.995	0.000
S24 Injury of nerves and spinal cord at thorax level	0.005	0.995	0.000
S22.5 Flail chest	0.005	0.995	0.000
M54.14 Radiculopathy (Thoracic region)	0.000	0.995	0.005
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.005	0.995	0.000
O40 Polyhydramnios	0.000	0.995	0.005
S21 Open wound of thorax	0.005	0.995	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.995	0.005
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.995	0.005
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.005	0.995	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.995	0.005
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.995	0.005
O36.5 Maternal care for poor foetal growth	0.000	0.995	0.005
S23.4 Sprain and strain of ribs and sternum	0.005	0.995	0.000
O43 Placental disorders	0.000	0.995	0.005
Z80.8 Family history of malignant neoplasm of other organs or systems	0.005	0.995	0.000
O42 Premature rupture of membranes	0.000	0.995	0.005
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.995	0.005
A40.0 Septicaemia due to streptococcus, group A	0.005	0.995	0.000
S29 Other and unspecified injuries of thorax	0.005	0.995	0.000
O31 Complications specific to multiple gestation	0.000	0.995	0.005
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.995	0.005
O41 Other disorders of amniotic fluid and membranes	0.000	0.995	0.005
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.004	0.995	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.004	0.995	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.004	0.995	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.004	0.995	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.004	0.995	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.004	0.995	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.004	0.995	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.004	0.995	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.004	0.995	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.004	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.995	0.005
L93.1 Subacute cutaneous lupus erythematosus	0.000	0.995	0.004
J93 Pneumothorax	0.000	0.995	0.005
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.995	0.004
S21.2 Open wound of back wall of thorax	0.004	0.995	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
O33 Maternal care for known or suspected disproportion	0.000	0.996	0.004
S23.5 Sprain and strain of other and unspecified parts of thorax	0.004	0.996	0.000
S23.3 Sprain and strain of thoracic spine	0.004	0.996	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.004	0.996	0.000
S23.1 Dislocation of thoracic vertebra	0.004	0.996	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.004	0.996	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
A40 Streptococcal septicaemia	0.004	0.996	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.996	0.004
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.004	0.996	0.000
O43.0 Placental transfusion syndromes	0.000	0.996	0.004
O46.8 Other antepartum haemorrhage	0.000	0.996	0.004
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.996	0.004
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.004	0.996	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.004	0.996	0.000
S25.8 Injury of other blood vessels of thorax	0.004	0.996	0.000
S25.7 Injury of multiple blood vessels of thorax	0.004	0.996	0.000
S25.5 Injury of intercostal blood vessels	0.004	0.996	0.000
S25.4 Injury of pulmonary blood vessels	0.004	0.996	0.000
S25.3 Injury of innominate or subclavian vein	0.004	0.996	0.000
S25.2 Injury of superior vena cava	0.004	0.996	0.000
S25.1 Injury of innominate or subclavian artery	0.004	0.996	0.000
S25.0 Injury of thoracic aorta	0.004	0.996	0.000
S26.9 Injury of heart, unspecified	0.004	0.996	0.000
S26.8 Other injuries of heart	0.004	0.996	0.000
S26.0 Injury of heart with haemopericardium	0.004	0.996	0.000
S28.1 Traumatic amputation of part of thorax	0.004	0.996	0.000
S28.0 Crushed chest	0.004	0.996	0.000
O43.9 Placental disorder, unspecified	0.000	0.996	0.004
S24.6 Injury of unspecified nerve of thorax	0.004	0.996	0.000
S24.5 Injury of other nerves of thorax	0.004	0.996	0.000
S24.4 Injury of thoracic sympathetic nerves	0.004	0.996	0.000
S24.3 Injury of peripheral nerves of thorax	0.004	0.996	0.000
S24.2 Injury of nerve root of thoracic spine	0.004	0.996	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.004	0.996	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.004	0.996	0.000
O30 Multiple gestation	0.000	0.996	0.004
S22.51 Flail chest (open)	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
J90-J94 Other diseases of pleura	0.000	0.996	0.004
R29.6 Tendency to fall, not elsewhere classified	0.000	0.996	0.004
C50.3 Lower-inner quadrant of breast	0.004	0.996	0.000
S21.8 Open wound of other parts of thorax	0.004	0.996	0.000
S21.7 Multiple open wounds of thoracic wall	0.004	0.996	0.000
S21.0 Open wound of breast	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.996	0.004
O43.2 Morbidly adherent placenta	0.000	0.996	0.004
M54.12 Radiculopathy (Cervical region)	0.000	0.996	0.004
S29.8 Other specified injuries of thorax	0.004	0.996	0.000
O45 Premature separation of placenta [abruptio placentae]	0.000	0.996	0.004
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.996	0.000
O43.1 Malformation of placenta	0.000	0.996	0.004
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.996	0.004
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.996	0.004
A40.2 Septicaemia due to streptococcus, group D	0.004	0.996	0.000
S29.7 Multiple injuries of thorax	0.003	0.996	0.000
R60 Oedema, not elsewhere classified	0.000	0.996	0.004
J94 Other pleural conditions	0.000	0.996	0.004
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.996	0.003
O31.0 Papyraceous foetus	0.000	0.996	0.003
O31.8 Other complications specific to multiple gestation	0.000	0.996	0.003
O41.0 Oligohydramnios	0.000	0.996	0.004
O47.9 False labour, unspecified	0.000	0.996	0.004
O43.8 Other placental disorders	0.000	0.996	0.003
S29.0 Injury of muscle and tendon at thorax level	0.003	0.996	0.000
O41.1 Infection of amniotic sac and membranes	0.000	0.996	0.003
S21.1 Open wound of front wall of thorax	0.003	0.996	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.004	0.996	0.000
O33.9 Maternal care for disproportion, unspecified	0.000	0.996	0.003
O36.9 Maternal care for foetal problem, unspecified	0.000	0.996	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.003
Q61.3 Polycystic kidney, unspecified	0.003	0.996	0.000
C77.9 Lymph node, unspecified	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.000	0.997	0.003
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.997	0.003
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.997	0.003
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.997	0.003
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.997	0.003
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.997	0.003
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.997	0.003
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
J94.1 Fibrothorax	0.000	0.997	0.003
A40.1 Septicaemia due to streptococcus, group B	0.003	0.997	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.997	0.003
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.997	0.003
A40.3 Septicaemia due to Streptococcus pneumoniae	0.003	0.997	0.000
J93.9 Pneumothorax, unspecified	0.000	0.997	0.003
O36.2 Maternal care for hydrops foetalis	0.000	0.997	0.003
I35.0 Aortic (valve) stenosis	0.000	0.997	0.003
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.997	0.003
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.997	0.003
S82.6 Fracture of lateral malleolus	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.003
C24.0 Extrahepatic bile duct	0.000	0.997	0.003
S21.9 Open wound of thorax, part unspecified	0.003	0.997	0.000
O30.1 Triplet pregnancy	0.000	0.997	0.003
J93.0 Spontaneous tension pneumothorax	0.000	0.997	0.003
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.003	0.997	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.003	0.997	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.003	0.997	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.003	0.997	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.003	0.997	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.003	0.997	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.000	0.997	0.003
O30.8 Other multiple gestation	0.000	0.997	0.003
O30.2 Quadruplet pregnancy	0.000	0.997	0.003
J94.2 Haemothorax	0.000	0.997	0.003
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.997	0.003
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.997	0.003
S22.1 Multiple fractures of thoracic spine	0.003	0.997	0.000
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
O44 Placenta praevia	0.000	0.997	0.003
O45.8 Other premature separation of placenta	0.000	0.997	0.003
O45.0 Premature separation of placenta with coagulation defect	0.000	0.997	0.003
S22.4 Multiple fractures of ribs	0.003	0.997	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.997	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.997	0.003
C18.3 Hepatic flexure	0.000	0.997	0.003
G83.4 Cauda equina syndrome	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.997	0.003
O36.1 Maternal care for other isoimmunisation	0.000	0.997	0.003
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
J94.0 Chylous effusion	0.000	0.997	0.003
J94.9 Pleural condition, unspecified	0.000	0.997	0.003
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
S59.9 Unspecified injury of forearm	0.000	0.997	0.003
S22.81 Fracture of other parts of bony thorax (open)	0.003	0.997	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.003	0.997	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.003	0.997	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.997	0.003
J93.8 Other pneumothorax	0.000	0.997	0.003
R60.1 Generalised oedema	0.000	0.997	0.003
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.997	0.003
K22.9 Disease of oesophagus, unspecified	0.000	0.997	0.003
S82.61 Fracture of lateral malleolus (open)	0.003	0.997	0.000
K29.0 Acute haemorrhagic gastritis	0.003	0.997	0.000
S22.2 Fracture of sternum	0.002	0.997	0.000
Y47.1 Benzodiazepines	0.000	0.997	0.003
Y48.4 Anaesthetic, unspecified	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.000	0.997	0.003
Q85.9 Phakomatosis, unspecified	0.003	0.997	0.000
Chapter X Diseases of the respiratory system	0.000	0.997	0.003
J94.8 Other specified pleural conditions	0.000	0.997	0.003
S22.3 Fracture of rib	0.002	0.997	0.000
E83.1 Disorders of iron metabolism	0.003	0.997	0.000
S82.7 Multiple fractures of lower leg	0.002	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.000	0.997	0.003
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.997	0.002
D12.8 Rectum	0.000	0.998	0.002
J38.4 Oedema of larynx	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.998	0.002
S22.11 Multiple fractures of thoracic spine (open)	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.002	0.998	0.000
O30.0 Twin pregnancy	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.998	0.002
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.998	0.002
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.998	0.002
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.998	0.002
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.998	0.002
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.998	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.998	0.002
O45.9 Premature separation of placenta, unspecified	0.001	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.998	0.002
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.998	0.002
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.000	0.998	0.002
Y48.1 Parenteral anaesthetics	0.000	0.998	0.002
Y48.0 Inhaled anaesthetics	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.998	0.002
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.998	0.002
Y47.4 Bromine compounds	0.000	0.998	0.002
Y47.3 Paraldehyde	0.000	0.998	0.002
Y47.2 Chloral derivatives	0.000	0.998	0.002
Y47.0 Barbiturates, not elsewhere classified	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.998	0.002
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.998	0.002
C24.9 Biliary tract, unspecified	0.000	0.998	0.002
Y48.3 Local anaesthetics	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
Y58 Bacterial vaccines	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
J45.9 Asthma, unspecified	0.000	0.998	0.002
N81.5 Vaginal enterocele	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.000	0.998	0.002
J15.5 Pneumonia due to Escherichia coli	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.998	0.002
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.000	0.998	0.002
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.998	0.002
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
C24.8 Overlapping lesion of biliary tract	0.000	0.998	0.002
J15.8 Other bacterial pneumonia	0.000	0.998	0.002
Y41.1 Antimycobacterial drugs	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.000	0.998	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
C24.1 Ampulla of Vater	0.000	0.998	0.002
J15.9 Bacterial pneumonia, unspecified	0.000	0.998	0.002
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.998	0.002
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.998	0.002
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.998	0.002
Q61 Cystic kidney disease	0.002	0.998	0.000
S59 Other and unspecified injuries of forearm	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.002
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.998	0.002
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.001
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.001
Y55.5 Anticommon cold drugs	0.000	0.998	0.001
Y55.3 Antitussives	0.000	0.998	0.001
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
Y55.0 Oxytocic drugs	0.000	0.998	0.001
Y58.9 Other and unspecified bacterial vaccines	0.000	0.998	0.001
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.998	0.001
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.998	0.001
Y58.5 Diphtheria vaccine	0.000	0.998	0.001
Y58.4 Tetanus vaccine	0.000	0.998	0.001
Y58.3 Plague vaccine	0.000	0.998	0.001
Y58.2 Cholera vaccine	0.000	0.998	0.001
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.998	0.001
F45.8 Other somatoform disorders	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.000	0.998	0.001
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
S54.0 Injury of ulnar nerve at forearm level	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.998	0.001
Y58.0 BCG vaccine	0.000	0.998	0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.998	0.002
S82.0 Fracture of patella	0.001	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.000	0.998	0.001
Y50.8 Other central nervous system stimulants	0.000	0.998	0.001
Y50.1 Opioid receptor antagonists	0.000	0.998	0.001
Y50.0 Analeptics	0.000	0.998	0.001
Y44 Agents primarily affecting blood constituents	0.000	0.998	0.002
D68.0 Von Willebrand's disease	0.000	0.998	0.002
G83.9 Paralytic syndrome, unspecified	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.001
O92.1 Cracked nipple associated with childbirth	0.000	0.998	0.001
Q61.9 Cystic kidney disease, unspecified	0.001	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.001	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.998	0.001
J98.6 Disorders of diaphragm	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.000	0.998	0.001
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
Y41.0 Sulphonamides	0.000	0.998	0.001
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.001
S82.1 Fracture of upper end of tibia	0.001	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.000	0.998	0.001
Y46.5 Valproic acid	0.000	0.998	0.001
Y46.3 Deoxybarbiturates	0.000	0.998	0.001
Y46.1 Oxazolidinediones	0.000	0.998	0.001
Y46.0 Succinimides	0.000	0.998	0.001
G96 Other disorders of central nervous system	0.000	0.998	0.001
J85 Abscess of lung and mediastinum	0.000	0.998	0.001
J95-J99 Other diseases of the respiratory system	0.000	0.998	0.001
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations