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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs148793625
log Bayes Factor = 14.7971
Chromosome 2   position 118,117,059  (GRCh37) Explore rs148793625 on Ensembl!
Variant rs148793625 is part of Cluster X0029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
R00 Abnormalities of heart beat
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
R07 Pain in throat and chest
0.987 0.013 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.987 0.013 0.000
Chapter X Diseases of the respiratory system
0.984 0.016 0.000
R00.1 Bradycardia, unspecified
0.983 0.017 0.000
R07.3 Other chest pain
0.979 0.021 0.000
M80-M85 Disorders of bone density and structure
0.970 0.030 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.968 0.032 0.000
S60-S69 Injuries to the wrist and hand
0.965 0.035 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.961 0.039 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.958 0.042 0.000
R11 Nausea and vomiting
0.956 0.044 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.943 0.057 0.000
J30-J39 Other diseases of upper respiratory tract
0.941 0.059 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.940 0.060 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.939 0.061 0.000
M05-M14 Inflammatory polyarthropathies
0.936 0.064 0.000
M81 Osteoporosis without pathological fracture
0.936 0.064 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
S70-S79 Injuries to the hip and thigh
0.932 0.068 0.000
Chapter XI Diseases of the digestive system
0.931 0.069 0.000
M20-M25 Other joint disorders
0.929 0.071 0.000
R00.0 Tachycardia, unspecified
0.927 0.073 0.000
F10.1 Harmful use
0.922 0.078 0.000
J09-J18 Influenza and pneumonia
0.921 0.079 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.913 0.087 0.000
M81.9 Osteoporosis, unspecified
0.912 0.088 0.000
M50-M54 Other dorsopathies
0.907 0.093 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.907 0.093 0.000
R00.2 Palpitations
0.904 0.096 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.904 0.096 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.901 0.099 0.000
E20-E35 Disorders of other endocrine glands
0.900 0.100 0.000
S50-S59 Injuries to the elbow and forearm
0.894 0.106 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.890 0.110 0.000
S61 Open wound of wrist and hand
0.890 0.110 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.890 0.110 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.888 0.112 0.000
J34 Other disorders of nose and nasal sinuses
0.886 0.114 0.000
M15-M19 Arthrosis
0.885 0.115 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.880 0.120 0.000
Chapter I Certain infectious and parasitic diseases
0.879 0.121 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.874 0.126 0.000
D60-D64 Aplastic and other anaemias
0.870 0.130 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.869 0.131 0.000
Chapter VI Diseases of the nervous system
0.865 0.135 0.000
S72 Fracture of femur
0.862 0.138 0.000
J33 Nasal polyp
0.859 0.141 0.000
R10 Abdominal and pelvic pain
0.857 0.143 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.857 0.143 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.856 0.144 0.000
S61.0 Open wound of finger(s) without damage to nail
0.850 0.150 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.850 0.150 0.000
J18 Pneumonia, organism unspecified
0.849 0.151 0.000
S20-S29 Injuries to the thorax
0.840 0.160 0.000
K30 Dyspepsia
0.839 0.161 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.839 0.161 0.000
S62 Fracture at wrist and hand level
0.837 0.163 0.000
R05 Cough
0.837 0.163 0.000
F30-F39 Mood [affective] disorders
0.834 0.166 0.000
M23 Internal derangement of knee
0.832 0.168 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.830 0.170 0.000
F10.4 Withdrawal state with delirium
0.827 0.173 0.000
M54 Dorsalgia
0.825 0.175 0.000
J00-J06 Acute upper respiratory infections
0.824 0.176 0.000
S80-S89 Injuries to the knee and lower leg
0.822 0.178 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.821 0.179 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.820 0.180 0.000
M13 Other arthritis
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
F10.3 Withdrawal state
0.813 0.187 0.000
M17 Gonarthrosis [arthrosis of knee]
0.811 0.189 0.000
T86 Failure and rejection of transplanted organs and tissues
0.811 0.189 0.000
S72.1 Pertrochanteric fracture
0.810 0.190 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.809 0.191 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.809 0.191 0.000
J95-J99 Other diseases of the respiratory system
0.807 0.193 0.000
J60-J70 Lung diseases due to external agents
0.806 0.194 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.804 0.196 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.802 0.198 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.802 0.198 0.000
R01 Cardiac murmurs and other cardiac sounds
0.799 0.201 0.000
R07.2 Precordial pain
0.799 0.201 0.000
K70-K77 Diseases of liver
0.799 0.201 0.000
M25 Other joint disorders, not elsewhere classified
0.796 0.204 0.000
D64 Other anaemias
0.795 0.205 0.000
S52 Fracture of forearm
0.795 0.205 0.000
S00-S09 Injuries to the head
0.792 0.208 0.000
F10.2 Dependence syndrome
0.792 0.208 0.000
J39 Other diseases of upper respiratory tract
0.791 0.209 0.000
Y40 Systemic antibiotics
0.788 0.212 0.000
B95-B98 Bacterial, viral and other infectious agents
0.787 0.213 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.785 0.215 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.783 0.217 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.783 0.217 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.783 0.217 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.782 0.218 0.000
R42 Dizziness and giddiness
0.781 0.219 0.000
K31 Other diseases of stomach and duodenum
0.779 0.221 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.778 0.222 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
R02 Gangrene, not elsewhere classified
0.776 0.224 0.000
J33.9 Nasal polyp, unspecified
0.774 0.226 0.000
S72.10 Pertrochanteric fracture (closed)
0.772 0.228 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.768 0.232 0.000
R94 Abnormal results of function studies
0.767 0.233 0.000
J34.3 Hypertrophy of nasal turbinates
0.764 0.236 0.000
E22 Hyperfunction of pituitary gland
0.763 0.237 0.000
D50-D53 Nutritional anaemias
0.763 0.237 0.000
O60-O75 Complications of labour and delivery
0.762 0.238 0.000
E10-E14 Diabetes mellitus
0.760 0.240 0.000
M85 Other disorders of bone density and structure
0.760 0.240 0.000
Y86 Sequelae of other accidents
0.760 0.240 0.000
Y83.8 Other surgical procedures
0.759 0.241 0.000
M84 Disorders of continuity of bone
0.758 0.242 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.758 0.242 0.000
T66-T78 Other and unspecified effects of external causes
0.757 0.243 0.000
K14 Diseases of tongue
0.757 0.243 0.000
G20-G26 Extrapyramidal and movement disorders
0.757 0.243 0.000
K27 Peptic ulcer, site unspecified
0.756 0.244 0.000
R10.4 Other and unspecified abdominal pain
0.756 0.244 0.000
M21 Other acquired deformities of limbs
0.755 0.244 0.000
M05 Seropositive rheumatoid arthritis
0.753 0.246 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.751 0.249 0.000
Chapter IX Diseases of the circulatory system
0.750 0.250 0.000
M06 Other rheumatoid arthritis
0.749 0.251 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.748 0.252 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.748 0.252 0.000
R18 Ascites
0.747 0.253 0.000
J11 Influenza, virus not identified
0.745 0.255 0.000
T90 Sequelae of injuries of head
0.743 0.257 0.000
M86-M90 Other osteopathies
0.742 0.258 0.000
D64.9 Anaemia, unspecified
0.742 0.258 0.000
J18.0 Bronchopneumonia, unspecified
0.741 0.259 0.000
J34.2 Deviated nasal septum
0.740 0.260 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.738 0.262 0.000
J03 Acute tonsillitis
0.736 0.264 0.000
M11 Other crystal arthropathies
0.736 0.264 0.000
M18 Arthrosis of first carpometacarpal joint
0.736 0.264 0.000
R07.1 Chest pain on breathing
0.736 0.264 0.000
F60-F69 Disorders of adult personality and behaviour
0.734 0.266 0.000
J18.1 Lobar pneumonia, unspecified
0.731 0.269 0.000
S79 Other and unspecified injuries of hip and thigh
0.731 0.269 0.000
M13.9 Arthritis, unspecified
0.730 0.270 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.729 0.270 0.000
M23.3 Other meniscus derangements
0.729 0.271 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.725 0.275 0.000
Y83.4 Other reconstructive surgery
0.724 0.276 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.723 0.277 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.721 0.279 0.000
D80-D89 Certain disorders involving the immune mechanism
0.721 0.279 0.000
F41 Other anxiety disorders
0.721 0.279 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.720 0.280 0.000
K11 Diseases of salivary glands
0.719 0.281 0.000
F31 Bipolar affective disorder
0.719 0.281 0.000
S67 Crushing injury of wrist and hand
0.718 0.282 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.718 0.282 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.716 0.284 0.000
T91 Sequelae of injuries of neck and trunk
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.285 0.000
M20 Acquired deformities of fingers and toes
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X60-X84 Intentional self-harm
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V80-V89 Other land transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
R26 Abnormalities of gait and mobility
0.711 0.289 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.710 0.290 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.708 0.292 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.708 0.292 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.708 0.292 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.708 0.292 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.708 0.292 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.706 0.293 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.706 0.294 0.000
V20-V29 Motorcycle rider injured in transport accident
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
A30-A49 Other bacterial diseases
0.702 0.298 0.000
J32 Chronic sinusitis
0.702 0.298 0.000
S00 Superficial injury of head
0.701 0.299 0.000
J33.0 Polyp of nasal cavity
0.701 0.299 0.000
S51 Open wound of forearm
0.700 0.300 0.000
W20-W49 Exposure to inanimate mechanical forces
0.700 0.300 0.000
K05 Gingivitis and periodontal diseases
0.699 0.300 0.000
M65-M68 Disorders of synovium and tendon
0.698 0.302 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.697 0.302 0.000
S81 Open wound of lower leg
0.697 0.303 0.000
M51 Other intervertebral disk disorders
0.697 0.303 0.000
E21.3 Hyperparathyroidism, unspecified
0.696 0.304 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.695 0.304 0.000
W00-W19 Falls
0.695 0.305 0.000
M83 Adult osteomalacia
0.695 0.305 0.000
M82 Osteoporosis in diseases classified elsewhere
0.695 0.305 0.000
M17.9 Gonarthrosis, unspecified
0.694 0.306 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.694 0.306 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.694 0.306 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.694 0.306 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.694 0.306 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.694 0.306 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.694 0.306 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.694 0.306 0.000
F11 Mental and behavioural disorders due to use of opioids
0.694 0.306 0.000
K35-K38 Diseases of appendix
0.693 0.307 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.692 0.307 0.000
E23 Hypofunction and other disorders of pituitary gland
0.692 0.308 0.000
S69 Other and unspecified injuries of wrist and hand
0.692 0.308 0.000
S65 Injury of blood vessels at wrist and hand level
0.692 0.308 0.000
S60 Superficial injury of wrist and hand
0.692 0.308 0.000
K74 Fibrosis and cirrhosis of liver
0.692 0.308 0.000
Y83.0 Surgical operation with transplant of whole organ
0.691 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.690 0.309 0.000
M19 Other arthrosis
0.691 0.309 0.000
S70 Superficial injury of hip and thigh
0.690 0.310 0.000
E29 Testicular dysfunction
0.690 0.310 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.689 0.311 0.000
E10 Insulin-dependent diabetes mellitus
0.688 0.312 0.000
S64 Injury of nerves at wrist and hand level
0.688 0.312 0.000
D51 Vitamin B12 deficiency anaemia
0.687 0.313 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.687 0.313 0.000
F10.9 Unspecified mental and behavioural disorder
0.687 0.313 0.000
F10.8 Other mental and behavioural disorders
0.687 0.313 0.000
F10.7 Residual and late-onset psychotic disorder
0.687 0.313 0.000
F10.6 Amnesic syndrome
0.687 0.313 0.000
F10.5 Psychotic disorder
0.687 0.313 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.687 0.313 0.000
R10.1 Pain localised to upper abdomen
0.686 0.314 0.000
R10.0 Acute abdomen
0.685 0.315 0.000
Y44 Agents primarily affecting blood constituents
0.684 0.316 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.684 0.316 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.682 0.318 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.682 0.318 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.681 0.319 0.000
K01 Embedded and impacted teeth
0.681 0.319 0.000
J98 Other respiratory disorders
0.680 0.320 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.680 0.320 0.000
M81.98 Osteoporosis, unspecified (Other)
0.680 0.320 0.000
Chapter VIII Diseases of the ear and mastoid process
0.680 0.320 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.679 0.320 0.000
T81 Complications of procedures, not elsewhere classified
0.679 0.321 0.000
Y40.9 Systemic antibiotic, unspecified
0.679 0.321 0.000
E00-E07 Disorders of thyroid gland
0.679 0.321 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.679 0.321 0.000
K04 Diseases of pulp and periapical tissues
0.678 0.322 0.000
S62.3 Fracture of other metacarpal bone
0.678 0.322 0.000
J69 Pneumonitis due to solids and liquids
0.678 0.322 0.000
S62.6 Fracture of other finger
0.678 0.322 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.677 0.323 0.000
Y95 Nosocomial condition
0.677 0.323 0.000
M17.3 Other posttraumatic gonarthrosis
0.677 0.323 0.000
M80 Osteoporosis with pathological fracture
0.677 0.323 0.000
E40-E46 Malnutrition
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
S72.3 Fracture of shaft of femur
0.675 0.325 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.675 0.325 0.000
J37 Chronic laryngitis and laryngotracheitis
0.674 0.325 0.000
J03.9 Acute tonsillitis, unspecified
0.674 0.326 0.000
M54.5 Low back pain
0.674 0.326 0.000
M07 Psoriatic and enteropathic arthropathies
0.673 0.327 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.673 0.327 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.672 0.328 0.000
M14 Arthropathies in other diseases classified elsewhere
0.671 0.329 0.000
M12 Other specific arthropathies
0.671 0.329 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.671 0.329 0.000
M08 Juvenile arthritis
0.671 0.329 0.000
M81.8 Other osteoporosis
0.671 0.329 0.000
M81.6 Localised osteoporosis [Lequesne]
0.671 0.329 0.000
M81.5 Idiopathic osteoporosis
0.671 0.329 0.000
M81.4 Drug-induced osteoporosis
0.671 0.329 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.671 0.329 0.000
M81.2 Osteoporosis of disuse
0.671 0.329 0.000
M81.1 Postoophorectomy osteoporosis
0.671 0.329 0.000
M81.0 Postmenopausal osteoporosis
0.671 0.329 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
M54.2 Cervicalgia
0.671 0.329 0.000
K09 Cysts of oral region, not elsewhere classified
0.670 0.330 0.000
Y85 Sequelae of transport accidents
0.670 0.330 0.000
T58 Toxic effect of carbon monoxide
0.669 0.330 0.000
K02 Dental caries
0.669 0.331 0.000
E16 Other disorders of pancreatic internal secretion
0.668 0.332 0.000
S52.5 Fracture of lower end of radius
0.668 0.332 0.000
S78 Traumatic amputation of hip and thigh
0.668 0.332 0.000
S77 Crushing injury of hip and thigh
0.668 0.332 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.668 0.332 0.000
S75 Injury of blood vessels at hip and thigh level
0.668 0.332 0.000
S74 Injury of nerves at hip and thigh level
0.668 0.332 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.668 0.332 0.000
S71 Open wound of hip and thigh
0.668 0.332 0.000
E28 Ovarian dysfunction
0.668 0.332 0.000
J39.2 Other diseases of pharynx
0.667 0.333 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.666 0.334 0.000
M34 Systemic sclerosis
0.666 0.334 0.000
M33 Dermatopolymyositis
0.666 0.334 0.000
M32 Systemic lupus erythematosus
0.666 0.334 0.000
M31 Other necrotising vasculopathies
0.666 0.334 0.000
M30 Polyarteritis nodosa and related conditions
0.666 0.334 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.665 0.335 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.665 0.335 0.000
S68 Traumatic amputation of wrist and hand
0.665 0.335 0.000
V10-V19 Pedal cyclist injured in transport accident
0.664 0.336 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.664 0.336 0.000
T93 Sequelae of injuries of lower limb
0.664 0.336 0.000
M10 Gout
0.664 0.336 0.000
M22 Disorders of patella
0.664 0.336 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.663 0.337 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.662 0.337 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.662 0.338 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.660 0.340 0.000
J17 Pneumonia in diseases classified elsewhere
0.660 0.340 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.660 0.340 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.660 0.340 0.000
J12 Viral pneumonia, not elsewhere classified
0.660 0.340 0.000
J10 Influenza due to identified influenza virus
0.660 0.340 0.000
J14 Pneumonia due to Haemophilus influenzae
0.660 0.340 0.000
J09 Influenza due to certain identified influenza virus
0.660 0.340 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.660 0.340 0.000
T92 Sequelae of injuries of upper limb
0.659 0.341 0.000
E21.0 Primary hyperparathyroidism
0.659 0.341 0.000
M54.9 Dorsalgia, unspecified
0.658 0.342 0.000
K26 Duodenal ulcer
0.658 0.342 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.657 0.343 0.000
L20-L30 Dermatitis and eczema
0.656 0.344 0.000
R07.0 Pain in throat
0.656 0.344 0.000
M23.8 Other internal derangements of knee
0.656 0.344 0.000
M50 Cervical disk disorders
0.655 0.344 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.655 0.345 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.655 0.345 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.655 0.345 0.000
T82.3 Mechanical complication of other vascular grafts
0.655 0.345 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.655 0.345 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.655 0.345 0.000
B35-B49 Mycoses
0.654 0.346 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.654 0.346 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.654 0.346 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.654 0.346 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.654 0.346 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.654 0.346 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.654 0.346 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.654 0.346 0.000
G25 Other extrapyramidal and movement disorders
0.653 0.347 0.000
S61.1 Open wound of finger(s) with damage to nail
0.653 0.347 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.652 0.348 0.000
D62 Acute posthaemorrhagic anaemia
0.652 0.348 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.651 0.349 0.000
M53 Other dorsopathies, not elsewhere classified
0.651 0.349 0.000
T82.1 Mechanical complication of cardiac electronic device
0.651 0.349 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.651 0.349 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.650 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.650 0.350 0.000
Y58 Bacterial vaccines
0.650 0.350 0.000
Y57 Other and unspecified drugs and medicaments
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.650 0.350 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.650 0.350 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.650 0.350 0.000
Y52 Agents primarily affecting the cardiovascular system
0.650 0.350 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.650 0.350 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.650 0.350 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.650 0.350 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.650 0.350 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.650 0.350 0.000
Y42.7 Androgens and anabolic congeners
0.649 0.351 0.000
Y83.5 Amputation of limb(s)
0.648 0.352 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.647 0.353 0.000
S42 Fracture of shoulder and upper arm
0.647 0.353 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.647 0.353 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.647 0.353 0.000
R17 Unspecified jaundice
0.646 0.354 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.645 0.355 0.000
E34 Other endocrine disorders
0.645 0.355 0.000
E32 Diseases of thymus
0.645 0.355 0.000
E31 Polyglandular dysfunction
0.645 0.355 0.000
E30 Disorders of puberty, not elsewhere classified
0.645 0.355 0.000
E27 Other disorders of adrenal gland
0.645 0.355 0.000
E26 Hyperaldosteronism
0.645 0.355 0.000
E25 Adrenogenital disorders
0.645 0.355 0.000
E24 Cushing's syndrome
0.645 0.355 0.000
E20 Hypoparathyroidism
0.645 0.355 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.644 0.356 0.000
M23.5 Chronic instability of knee
0.644 0.356 0.000
K25 Gastric ulcer
0.643 0.357 0.000
K12 Stomatitis and related lesions
0.643 0.357 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.642 0.358 0.000
S59 Other and unspecified injuries of forearm
0.641 0.359 0.000
S58 Traumatic amputation of forearm
0.641 0.359 0.000
S57 Crushing injury of forearm
0.641 0.359 0.000
S56 Injury of muscle and tendon at forearm level
0.641 0.359 0.000
S55 Injury of blood vessels at forearm level
0.641 0.359 0.000
S54 Injury of nerves at forearm level
0.641 0.359 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.641 0.359 0.000
S50 Superficial injury of forearm
0.641 0.359 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.641 0.359 0.000
G30-G32 Other degenerative diseases of the nervous system
0.640 0.360 0.000
F33 Recurrent depressive disorder
0.639 0.361 0.000
E50-E64 Other nutritional deficiencies
0.639 0.361 0.000
K70 Alcoholic liver disease
0.639 0.361 0.000
K14.9 Disease of tongue, unspecified
0.639 0.361 0.000
M25.5 Pain in joint
0.639 0.361 0.000
K31.5 Obstruction of duodenum
0.638 0.361 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.638 0.362 0.000
S61.7 Multiple open wounds of wrist and hand
0.638 0.362 0.000
F31.9 Bipolar affective disorder, unspecified
0.637 0.363 0.000
T98 Sequelae of other and unspecified effects of external causes
0.636 0.363 0.000
T95 Sequelae of burns, corrosions and frostbite
0.636 0.363 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.636 0.363 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.636 0.363 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.636 0.363 0.000
T17 Foreign body in respiratory tract
0.636 0.364 0.000
S61.8 Open wound of other parts of wrist and hand
0.635 0.365 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.635 0.365 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.635 0.365 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.635 0.365 0.000
R01.0 Benign and innocent cardiac murmurs
0.635 0.365 0.000
M15 Polyarthrosis
0.634 0.365 0.000
Q60-Q64 Congenital malformations of the urinary system
0.634 0.366 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.634 0.366 0.000
S62.5 Fracture of thumb
0.633 0.366 0.000
I78 Diseases of capillaries
0.633 0.367 0.000
R45 Symptoms and signs involving emotional state
0.633 0.367 0.000
E70-E90 Metabolic disorders
0.633 0.367 0.000
R94.5 Abnormal results of liver function studies
0.633 0.367 0.000
M21.3 Wrist or foot drop (acquired)
0.631 0.369 0.000
M54.6 Pain in thoracic spine
0.631 0.369 0.000
K10 Other diseases of jaws
0.631 0.369 0.000
K07 Dentofacial anomalies [including malocclusion]
0.631 0.369 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.631 0.369 0.000
K03 Other diseases of hard tissues of teeth
0.631 0.369 0.000
K00 Disorders of tooth development and eruption
0.631 0.369 0.000
K65-K67 Diseases of peritoneum
0.631 0.369 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.630 0.369 0.000
M25.8 Other specified joint disorders
0.630 0.370 0.000
M54.57 Low back pain (Lumbosacral region)
0.630 0.370 0.000
B99-B99 Other infectious diseases
0.630 0.370 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.630 0.370 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.630 0.370 0.000
B65-B83 Helminthiases
0.630 0.370 0.000
B50-B64 Protozoal diseases
0.630 0.370 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.630 0.370 0.000
B15-B19 Viral hepatitis
0.630 0.370 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.630 0.370 0.000
A80-A89 Viral infections of the central nervous system
0.630 0.370 0.000
A75-A79 Rickettsioses
0.630 0.370 0.000
A70-A74 Other diseases caused by chlamydiae
0.630 0.370 0.000
A65-A69 Other spirochaetal diseases
0.630 0.370 0.000
A20-A28 Certain zoonotic bacterial diseases
0.630 0.370 0.000
A15-A19 Tuberculosis
0.630 0.370 0.000
O73 Retained placenta and membranes, without haemorrhage
0.629 0.371 0.000
K13 Other diseases of lip and oral mucosa
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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