TreeWAS – Variant ID: rs1494508

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H04.5 Stenosis and insufficiency of lachrymal passages	0.076	0.924	0.000
H04.1 Other disorders of lachrymal gland	0.073	0.927	0.000
H04 Disorders of lachrymal system	0.073	0.927	0.000
H04.4 Chronic inflammation of lachrymal passages	0.067	0.933	0.000
H04.2 Epiphora	0.059	0.941	0.000
H04.0 Dacryoadenitis	0.054	0.946	0.000
H04.6 Other changes in lachrymal passages	0.050	0.950	0.000
H04.8 Other disorders of lachrymal system	0.050	0.950	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.047	0.953	0.000
H04.9 Disorder of lachrymal system, unspecified	0.043	0.956	0.000
N50.1 Vascular disorders of male genital organs	0.017	0.983	0.000
N50.8 Other specified disorders of male genital organs	0.017	0.983	0.000
N50 Other disorders of male genital organs	0.016	0.984	0.000
D22.0 Melanocytic naevi of lip	0.000	0.984	0.016
T78.4 Allergy, unspecified	0.014	0.986	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.014	0.986	0.000
N50.0 Atrophy of testis	0.013	0.986	0.000
H05.2 Exophthalmic conditions	0.013	0.987	0.000
H05 Disorders of orbit	0.013	0.987	0.000
H05.4 Enophthalmos	0.012	0.988	0.000
Z93.0 Tracheostomy status	0.000	0.988	0.012
N50.9 Disorder of male genital organs, unspecified	0.011	0.989	0.000
E87.7 Fluid overload	0.000	0.990	0.010
Z04.3 Examination and observation following other accident	0.000	0.990	0.010
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.990	0.010
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.010	0.990	0.000
H05.3 Deformity of orbit	0.010	0.990	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.990	0.010
H05.9 Disorder of orbit, unspecified	0.009	0.991	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.009	0.991	0.000
H05.1 Chronic inflammatory disorders of orbit	0.009	0.991	0.000
H05.8 Other disorders of orbit	0.009	0.991	0.000
H01 Other inflammation of eyelid	0.009	0.991	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.991	0.009
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.992	0.008
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.992	0.008
H03 Disorders of eyelid in diseases classified elsewhere	0.008	0.992	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.008	0.992	0.000
Z04 Examination and observation for other reasons	0.000	0.992	0.008
D84 Other immunodeficiencies	0.000	0.992	0.008
H00 Hordeolum and chalazion	0.008	0.992	0.000
H05.0 Acute inflammation of orbit	0.008	0.992	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.992	0.008
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.993	0.007
D84.9 Immunodeficiency, unspecified	0.000	0.993	0.007
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.993	0.007
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.993	0.007
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.993	0.007
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.993	0.007
H01.9 Inflammation of eyelid, unspecified	0.007	0.993	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.993	0.007
H06.3 Other disorders of orbit in diseases classified elsewhere	0.007	0.993	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.007	0.993	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.007	0.993	0.000
D84.1 Defects in the complement system	0.000	0.993	0.007
H01.8 Other specified inflammation of eyelid	0.007	0.993	0.000
T17.2 Foreign body in pharynx	0.000	0.993	0.007
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.993	0.006
N23 Unspecified renal colic	0.007	0.993	0.000
D84.8 Other specified immunodeficiencies	0.000	0.994	0.006
K02.9 Dental caries, unspecified	0.000	0.994	0.006
H01.1 Non-infectious dermatoses of eyelid	0.006	0.994	0.000
D83 Common variable immunodeficiency	0.000	0.994	0.006
Z04.6 General psychiatric examination, requested by authority	0.000	0.994	0.006
H00.0 Hordeolum and other deep inflammation of eyelid	0.006	0.994	0.000
T94.1 Sequelae of injuries, not specified by body region	0.000	0.994	0.006
H06.2 Dysthyroid exophthalmos	0.006	0.994	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.006	0.994	0.000
H57.8 Other specified disorders of eye and adnexa	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.994	0.006
Z04.5 Examination and observation following other inflicted injury	0.000	0.994	0.006
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.994	0.006
Z04.0 Blood-alcohol and blood-drug test	0.000	0.994	0.006
Z04.2 Examination and observation following work accident	0.000	0.994	0.006
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.994	0.006
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.006	0.994	0.000
H57 Other disorders of eye and adnexa	0.006	0.994	0.000
D81 Combined immunodeficiencies	0.000	0.994	0.006
D83.9 Common variable immunodeficiency, unspecified	0.000	0.994	0.005
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.994	0.005
M47.86 Other spondylosis (Lumbar region)	0.000	0.995	0.005
D86 Sarcoidosis	0.000	0.995	0.005
Z89.4 Acquired absence of foot and ankle	0.000	0.995	0.005
D86.8 Sarcoidosis of other and combined sites	0.000	0.995	0.005
K86.3 Pseudocyst of pancreas	0.000	0.995	0.005
J81 Pulmonary oedema	0.000	0.995	0.005
D82 Immunodeficiency associated with other major defects	0.000	0.995	0.005
H01.0 Blepharitis	0.005	0.995	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.995	0.005
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.995	0.005
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.995	0.005
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.995	0.005
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.004	0.995	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.995	0.005
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.995	0.005
Z04.1 Examination and observation following transport accident	0.000	0.995	0.005
D89.3 Immune reconstitution syndrome	0.000	0.995	0.004
D89.1 Cryoglobulinaemia	0.000	0.995	0.004
D86.9 Sarcoidosis, unspecified	0.000	0.995	0.005
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.996	0.004
D81.8 Other combined immunodeficiencies	0.000	0.996	0.004
D81.7 Major histocompatibility complex class II deficiency	0.000	0.996	0.004
D81.6 Major histocompatibility complex class I deficiency	0.000	0.996	0.004
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.996	0.004
D81.4 Nezelof's syndrome	0.000	0.996	0.004
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.996	0.004
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.996	0.004
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.996	0.004
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.996	0.004
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.996	0.004
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.996	0.004
J32.2 Chronic ethmoidal sinusitis	0.000	0.996	0.004
H57.0 Anomalies of pupillary function	0.004	0.996	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.004	0.996	0.000
H57.1 Ocular pain	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.996	0.003
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.996	0.003
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.996	0.003
D82.2 Immunodeficiency with short-limbed stature	0.000	0.996	0.003
D82.0 Wiskott-Aldrich syndrome	0.000	0.996	0.003
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.996	0.003
S80.8 Other superficial injuries of lower leg	0.000	0.996	0.004
D86.3 Sarcoidosis of skin	0.000	0.996	0.003
L23 Allergic contact dermatitis	0.004	0.996	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.003	0.997	0.000
N21 Calculus of lower urinary tract	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.000	0.997	0.003
L23.9 Allergic contact dermatitis, unspecified cause	0.003	0.997	0.000
D82.1 Di George's syndrome	0.000	0.997	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.997	0.003
L23.0 Allergic contact dermatitis due to metals	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
L23.8 Allergic contact dermatitis due to other agents	0.003	0.997	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.997	0.003
J95.0 Tracheostomy malfunction	0.000	0.997	0.003
N21.1 Calculus in urethra	0.003	0.997	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.003	0.997	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.003	0.997	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.997	0.003
T78 Adverse effects, not elsewhere classified	0.003	0.997	0.000
N20-N23 Urolithiasis	0.003	0.997	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.000	0.997	0.003
L23.7 Allergic contact dermatitis due to plants, except food	0.003	0.997	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.003	0.997	0.000
L23.4 Allergic contact dermatitis due to dyes	0.003	0.997	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.003	0.997	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.003	0.997	0.000
K02 Dental caries	0.000	0.997	0.003
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
M54.22 Cervicalgia (Cervical region)	0.000	0.997	0.003
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
S62.51 Fracture of thumb (open)	0.000	0.997	0.003
N99.4 Postprocedural pelvic peritoneal adhesions	0.003	0.997	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.997	0.003
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.000	0.997	0.002
M66.4 Spontaneous rupture of other tendons	0.000	0.997	0.003
N21.8 Other lower urinary tract calculus	0.002	0.997	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.000	0.997	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
H00.1 Chalazion	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.998	0.002
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.998	0.002
M66 Spontaneous rupture of synovium and tendon	0.000	0.998	0.002
N22 Calculus of urinary tract in diseases classified elsewhere	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.000	0.998	0.002
S82.0 Fracture of patella	0.002	0.998	0.000
K02.5 Caries with pulp exposure	0.000	0.998	0.002
K02.4 Odontoclasia	0.000	0.998	0.002
K02.3 Arrested dental caries	0.000	0.998	0.002
K02.2 Caries of cementum	0.000	0.998	0.002
K02.0 Caries limited to enamel	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
K02.8 Other dental caries	0.000	0.998	0.002
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.998	0.002
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
K02.1 Caries of dentin	0.000	0.998	0.002
M66.2 Spontaneous rupture of extensor tendons	0.000	0.998	0.002
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
I82.2 Embolism and thrombosis of vena cava	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
M66.3 Spontaneous rupture of flexor tendons	0.000	0.998	0.002
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.000	0.998	0.002
M66.48 Spontaneous rupture of other tendons (Other)	0.000	0.998	0.002
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.000	0.998	0.002
M66.44 Spontaneous rupture of other tendons (Hand)	0.000	0.998	0.002
M66.43 Spontaneous rupture of other tendons (Forearm)	0.000	0.998	0.002
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.000	0.998	0.002
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.000	0.998	0.002
M66.5 Spontaneous rupture of unspecified tendon	0.000	0.998	0.002
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.002	0.998	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.000	0.998	0.002
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.000	0.998	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
S42.4 Fracture of lower end of humerus	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.002	0.998	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.000	0.998	0.002
M66.1 Rupture of synovium	0.000	0.998	0.002
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.002	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.000	0.998	0.002
M66.08 Rupture of popliteal cyst-Other	0.000	0.998	0.002
M66.07 Rupture of popliteal cyst-Ankle/foot	0.000	0.998	0.002
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.000	0.998	0.002
M66.04 Rupture of popliteal cyst-Hand	0.000	0.998	0.002
M66.03 Rupture of popliteal cyst-Forearm	0.000	0.998	0.002
M66.02 Rupture of popliteal cyst-Upper arm	0.000	0.998	0.002
M66.01 Rupture of popliteal cyst-Shldr region	0.000	0.998	0.002
M66.00 Rupture of popliteal cyst-Mult sites	0.000	0.998	0.002
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
S31.4 Open wound of vagina and vulva	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.000	0.998	0.002
M66.28 Spontaneous rupture of extensor tendons-Other	0.000	0.998	0.002
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.000	0.998	0.002
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.000	0.998	0.002
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.000	0.998	0.002
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.000	0.998	0.002
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.000	0.998	0.002
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.998	0.002
S31.0 Open wound of lower back and pelvis	0.000	0.998	0.002
Z11.5 Special screening examination for other viral diseases	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.002
S52.0 Fracture of upper end of ulna	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.002	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.000	0.998	0.002
M66.38 Spontaneous rupture of flexor tendons (Other)	0.000	0.998	0.002
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.000	0.998	0.002
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.000	0.998	0.002
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.000	0.998	0.002
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.000	0.998	0.002
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.000	0.998	0.002
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.000	0.998	0.002
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
N99.1 Postprocedural urethral stricture	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.000	0.998	0.002
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.000	0.998	0.002
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.000	0.998	0.002
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.000	0.998	0.002
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.000	0.998	0.002
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.000	0.998	0.002
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.000	0.998	0.002
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.000	0.998	0.002
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
W15.8 Other specified place	0.000	0.998	0.002
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.000	0.998	0.002
C50.5 Lower-outer quadrant of breast	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.998	0.002
S31 Open wound of abdomen, lower back and pelvis	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
S42.2 Fracture of upper end of humerus	0.000	0.998	0.002
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.000	0.998	0.001
S31.8 Open wound of other and unspecified parts of abdomen	0.000	0.998	0.002
S37.0 Injury of kidney	0.000	0.998	0.002
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.998	0.002
M66.19 Rupture of synovium (Site unspecified)	0.000	0.998	0.001
M66.18 Rupture of synovium (Other)	0.000	0.998	0.001
M66.17 Rupture of synovium (Ankle and foot)	0.000	0.998	0.001
M66.16 Rupture of synovium (Lower leg)	0.000	0.998	0.001
M66.15 Rupture of synovium (Pelvic region and thigh)	0.000	0.998	0.001
M66.14 Rupture of synovium (Hand)	0.000	0.998	0.001
M66.13 Rupture of synovium (Forearm)	0.000	0.998	0.001
M66.12 Rupture of synovium (Upper arm)	0.000	0.998	0.001
M66.11 Rupture of synovium (Shoulder region)	0.000	0.998	0.001
M66.10 Rupture of synovium (Multiple sites)	0.000	0.998	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
G11.1 Early-onset cerebellar ataxia	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.998	0.002
S42 Fracture of shoulder and upper arm	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.000	0.998	0.001
S31.3 Open wound of scrotum and testes	0.000	0.998	0.001
J46 Status asthmaticus	0.000	0.998	0.002
Z43.0 Attention to tracheostomy	0.000	0.998	0.002
S37 Injury of urinary and pelvic organs	0.000	0.998	0.002
S37.20 Injury of bladder (without open wound into cavity)	0.000	0.998	0.001
S30.0 Contusion of lower back and pelvis	0.000	0.998	0.001
S31.5 Open wound of other and unspecified external genital organs	0.000	0.998	0.001
S37.2 Injury of bladder	0.000	0.998	0.001
G11 Hereditary ataxia	0.001	0.998	0.000
Z89 Acquired absence of limb	0.000	0.998	0.002
S42.21 Fracture of upper end of humerus (open)	0.000	0.998	0.001
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.000	0.998	0.001
S31.2 Open wound of penis	0.000	0.998	0.001
S37.3 Injury of urethra	0.000	0.998	0.001
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.998	0.001
S37.01 Injury of kidney (with open wound into cavity)	0.000	0.998	0.001
S37.30 Injury of urethra (without open wound into cavity)	0.000	0.998	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.001	0.998	0.000
L60.9 Nail disorder, unspecified	0.001	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.001	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.000	0.998	0.001
C26.0 Intestinal tract, part unspecified	0.001	0.999	0.000
L27.2 Dermatitis due to ingested food	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.999	0.001
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.999	0.001
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
F32.1 Moderate depressive episode	0.001	0.999	0.000
G12.2 Motor neuron disease	0.001	0.999	0.000
J47 Bronchiectasis	0.000	0.999	0.001
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.999	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.000	0.999	0.001
Z63.8 Other specified problems related to primary support group	0.000	0.999	0.001
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.999	0.001
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
I78.8 Other diseases of capillaries	0.001	0.999	0.000
N99.0 Postprocedural renal failure	0.001	0.999	0.000
R61.1 Generalised hyperhidrosis	0.001	0.999	0.000
S37.9 Injury of unspecified pelvic organ	0.000	0.999	0.001
S37.8 Injury of other pelvic organs	0.000	0.999	0.001
S37.7 Injury of multiple pelvic organs	0.000	0.999	0.001
S37.6 Injury of uterus	0.000	0.999	0.001
S37.5 Injury of Fallopian tube	0.000	0.999	0.001
S37.4 Injury of ovary	0.000	0.999	0.001
S37.1 Injury of ureter	0.000	0.999	0.001
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.999	0.001
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.999	0.001
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.999	0.001
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.999	0.001
S37.21 Injury of bladder (with open wound into cavity)	0.000	0.999	0.001
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000
G11.2 Late-onset cerebellar ataxia	0.001	0.999	0.000
G11.0 Congenital nonprogressive ataxia	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.999	0.001
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.999	0.001
Z89.1 Acquired absence of hand and wrist	0.000	0.999	0.001
I85 Oesophageal varices	0.000	0.999	0.001
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.999	0.001
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.999	0.001
S37.31 Injury of urethra (with open wound into cavity)	0.000	0.999	0.001
J43.9 Emphysema, unspecified	0.000	0.999	0.001
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.001	0.999	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.999	0.001
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
S42.31 Fracture of shaft of humerus (open)	0.000	0.999	0.001
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.999	0.001
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.999	0.001
Y79.8 Miscellaneous devices, not elsewhere classified	0.000	0.999	0.001
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.000	0.999	0.001
Y79.0 Diagnostic and monitoring devices	0.000	0.999	0.001
T17 Foreign body in respiratory tract	0.000	0.999	0.001
M23.49 Loose body in knee-Unspec lig/men	0.000	0.999	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
S41.1 Open wound of upper arm	0.000	0.999	0.001
T51.9 Alcohol, unspecified	0.000	0.999	0.001
R61 Hyperhidrosis	0.001	0.999	0.000
M79.70 Fibromyalgia (Multiple sites)	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.999	0.001
A15.0 Tuberculosis of lung, confirmed by sputum microscopy with or without culture	0.001	0.999	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
W02.9 Unspecified place	0.000	0.999	0.001
I78 Diseases of capillaries	0.001	0.999	0.000
T66 Unspecified effects of radiation	0.001	0.999	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.999	0.001
N92.3 Ovulation bleeding	0.001	0.999	0.000
Q44.6 Cystic disease of liver	0.001	0.999	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.999	0.001
S37.11 Injury of ureter (with open wound into cavity)	0.000	0.999	0.001
S37.10 Injury of ureter (without open wound into cavity)	0.000	0.999	0.001
S37.41 Injury of ovary (with open wound into cavity)	0.000	0.999	0.001
S37.40 Injury of ovary (without open wound into cavity)	0.000	0.999	0.001
S37.51 Injury of fallopian tube (with open wound into cavity)	0.000	0.999	0.001
S37.50 Injury of fallopian tube (without open wound into cavity)	0.000	0.999	0.001
S37.61 Injury of uterus (with open wound into cavity)	0.000	0.999	0.001
S37.60 Injury of uterus (without open wound into cavity)	0.000	0.999	0.001
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.000	0.999	0.001
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.000	0.999	0.001
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.000	0.999	0.001
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.000	0.999	0.001
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.000	0.999	0.001
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.000	0.999	0.001
A15.2 Tuberculosis of lung, confirmed histologically	0.001	0.999	0.000
A18.1 Tuberculosis of genito-urinary system	0.001	0.999	0.000
J95.5 Postprocedural subglottic stenosis	0.000	0.999	0.001
S31.1 Open wound of abdominal wall	0.000	0.999	0.001
S42.3 Fracture of shaft of humerus	0.000	0.999	0.001
S62.5 Fracture of thumb	0.000	0.999	0.001
Z89.9 Acquired absence of limb, unspecified	0.000	0.999	0.001
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.999	0.001
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.999	0.001
J95.4 Mendelson's syndrome	0.000	0.999	0.001
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.999	0.001
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.999	0.001
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.000	0.999	0.001
R61.0 Localised hyperhidrosis	0.001	0.999	0.000
S30.2 Contusion of external genital organs	0.000	0.999	0.001
S30.1 Contusion of abdominal wall	0.000	0.999	0.001
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.999	0.001
Z89.6 Acquired absence of leg above knee	0.000	0.999	0.001
R02 Gangrene, not elsewhere classified	0.000	0.999	0.001
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.999	0.001
B17.1 Acute hepatitis C	0.000	0.999	0.001
G44.2 Tension-type headache	0.000	0.999	0.001
S62.4 Multiple fractures of metacarpal bones	0.000	0.999	0.001
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.999	0.001
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.999	0.001
K08.8 Other specified disorders of teeth and supporting structures	0.001	0.999	0.000
M21.8 Other specified acquired deformities of limbs	0.000	0.999	0.001
Q24.5 Malformation of coronary vessels	0.000	0.999	0.001
T17.4 Foreign body in trachea	0.000	0.999	0.001
T17.1 Foreign body in nostril	0.000	0.999	0.001
T17.0 Foreign body in nasal sinus	0.000	0.999	0.001
Z74.2 Need for assistance at home and no other household member able to render care	0.001	0.999	0.000
Z74.0 Reduced mobility	0.001	0.999	0.000
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.999	0.001
D43.2 Brain, unspecified	0.001	0.999	0.000
L27 Dermatitis due to substances taken internally	0.001	0.999	0.000
R58 Haemorrhage, not elsewhere classified	0.000	0.999	0.001
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
A18.0 Tuberculosis of bones and joints	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.001	0.999	0.000
T73.3 Exhaustion due to excessive exertion	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.999	0.001
T73 Effects of other deprivation	0.001	0.999	0.000
T66-T78 Other and unspecified effects of external causes	0.001	0.999	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.999	0.001
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.999	0.001
H47.1 Papilloedema, unspecified	0.000	0.999	0.001
M89.8 Other specified disorders of bone	0.001	0.999	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.999	0.001
T92.9 Sequelae of unspecified injury of upper limb	0.001	0.999	0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.001	0.999	0.000
G12 Spinal muscular atrophy and related syndromes	0.001	0.999	0.000
N25 Disorders resulting from impaired renal tubular function	0.001	0.999	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.999	0.001
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.999	0.001
T56.8 Other metals	0.000	0.999	0.001
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.999	0.001
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.999	0.001
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.999	0.001
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.999	0.001
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.999	0.001
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.999	0.001
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.999	0.001
C49.3 Connective and soft tissue of thorax	0.000	0.999	0.001
C77.1 Intrathoracic lymph nodes	0.001	0.999	0.000
D39.1 Ovary	0.001	0.999	0.000
D43.0 Brain, supratentorial	0.001	0.999	0.000
I78.9 Disease of capillaries, unspecified	0.001	0.999	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
L27.9 Dermatitis due to unspecified substance taken internally	0.001	0.999	0.000
L27.8 Dermatitis due to other substances taken internally	0.001	0.999	0.000
M00.9 Pyogenic arthritis, unspecified	0.000	0.999	0.001
N25.0 Renal osteodystrophy	0.001	0.999	0.000
O12.1 Gestational proteinuria	0.001	0.999	0.000
T17.3 Foreign body in larynx	0.000	0.999	0.001
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.001	0.999	0.000
A18 Tuberculosis of other organs	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations