TreeWAS – Variant ID: rs149808359

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XII Diseases of the skin and subcutaneous tissue	0.865	0.135	0.000
# Top node	0.863	0.137	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.855	0.145	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.852	0.148	0.000
Chapter VI Diseases of the nervous system	0.831	0.169	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.818	0.182	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.818	0.182	0.000
Chapter II Neoplasms	0.814	0.186	0.000
L82 Seborrhoeic keratosis	0.806	0.194	0.000
E10-E14 Diabetes mellitus	0.797	0.203	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.789	0.211	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.781	0.219	0.000
E65-E68 Obesity and other hyperalimentation	0.769	0.231	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.741	0.258	0.000
Chapter X Diseases of the respiratory system	0.737	0.263	0.000
S00-S09 Injuries to the head	0.733	0.267	0.000
L60-L75 Disorders of skin appendages	0.732	0.268	0.000
E11 Non-insulin-dependent diabetes mellitus	0.727	0.273	0.000
Chapter V Mental and behavioural disorders	0.725	0.275	0.000
S80-S89 Injuries to the knee and lower leg	0.716	0.284	0.000
C15-C26 Malignant neoplasms of digestive organs	0.715	0.285	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.712	0.288	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.709	0.291	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.709	0.291	0.000
E66 Obesity	0.709	0.291	0.000
L03 Cellulitis	0.703	0.297	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.702	0.298	0.000
E70-E90 Metabolic disorders	0.700	0.300	0.000
J30-J39 Other diseases of upper respiratory tract	0.696	0.304	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.691	0.309	0.000
E10 Insulin-dependent diabetes mellitus	0.689	0.311	0.000
G20-G26 Extrapyramidal and movement disorders	0.682	0.318	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.678	0.322	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.677	0.323	0.000
J33 Nasal polyp	0.675	0.325	0.000
E66.9 Obesity, unspecified	0.671	0.329	0.000
L50-L54 Urticaria and erythema	0.665	0.335	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.663	0.337	0.000
S60-S69 Injuries to the wrist and hand	0.661	0.339	0.000
T66-T78 Other and unspecified effects of external causes	0.659	0.341	0.000
J33.9 Nasal polyp, unspecified	0.658	0.342	0.000
J09-J18 Influenza and pneumonia	0.653	0.347	0.000
E20-E35 Disorders of other endocrine glands	0.652	0.348	0.000
G56 Mononeuropathies of upper limb	0.651	0.349	0.000
L98.0 Pyogenic granuloma	0.650	0.350	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.645	0.355	0.000
C44 Other malignant neoplasms of skin	0.642	0.358	0.000
S00 Superficial injury of head	0.641	0.359	0.000
D00-D09 In situ neoplasms	0.640	0.360	0.000
L85 Other epidermal thickening	0.638	0.362	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.637	0.363	0.000
E86 Volume depletion	0.635	0.365	0.000
O00-O08 Pregnancy with abortive outcome	0.631	0.369	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.631	0.369	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.629	0.371	0.000
C50-C50 Malignant neoplasm of breast	0.627	0.373	0.000
E11.9 Without complications	0.625	0.375	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.624	0.376	0.000
L89 Decubitus ulcer	0.624	0.376	0.000
G35 Multiple sclerosis	0.622	0.378	0.000
S90-S99 Injuries to the ankle and foot	0.621	0.378	0.000
L10-L14 Bullous disorders	0.620	0.380	0.000
C18 Malignant neoplasm of colon	0.620	0.380	0.000
Chapter XXII Codes for special purposes	0.619	0.381	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.619	0.381	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.619	0.381	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.619	0.381	0.000
G30-G32 Other degenerative diseases of the nervous system	0.619	0.381	0.000
L91 Hypertrophic disorders of skin	0.618	0.382	0.000
G40-G47 Episodic and paroxysmal disorders	0.616	0.384	0.000
L20-L30 Dermatitis and eczema	0.613	0.387	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.613	0.387	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.613	0.387	0.000
L94 Other localised connective tissue disorders	0.613	0.387	0.000
L93 Lupus erythematosus	0.613	0.387	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.613	0.387	0.000
L87 Transepidermal elimination disorders	0.613	0.387	0.000
L88 Pyoderma gangrenosum	0.613	0.387	0.000
L86 Keratoderma in diseases classified elsewhere	0.613	0.387	0.000
L84 Corns and callosities	0.613	0.387	0.000
L83 Acanthosis nigricans	0.613	0.387	0.000
L80 Vitiligo	0.613	0.387	0.000
Chapter VIII Diseases of the ear and mastoid process	0.612	0.388	0.000
E40-E46 Malnutrition	0.611	0.389	0.000
S70-S79 Injuries to the hip and thigh	0.610	0.390	0.000
S01 Open wound of head	0.610	0.390	0.000
E50-E64 Other nutritional deficiencies	0.609	0.391	0.000
S82 Fracture of lower leg, including ankle	0.606	0.394	0.000
J60-J70 Lung diseases due to external agents	0.604	0.396	0.000
L03.0 Cellulitis of finger and toe	0.604	0.396	0.000
C44.7 Skin of lower limb, including hip	0.600	0.400	0.000
G90-G99 Other disorders of the nervous system	0.600	0.400	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.599	0.400	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.599	0.401	0.000
E11.3 With ophthalmic complications	0.598	0.402	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.597	0.403	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.596	0.403	0.000
G70-G73 Diseases of myoneural junction and muscle	0.596	0.404	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.596	0.404	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.596	0.404	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.594	0.405	0.000
E16 Other disorders of pancreatic internal secretion	0.594	0.406	0.000
L08 Other local infections of skin and subcutaneous tissue	0.592	0.408	0.000
G51 Facial nerve disorders	0.591	0.409	0.000
M05-M14 Inflammatory polyarthropathies	0.587	0.413	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.586	0.413	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.586	0.413	0.000
L98.5 Mucinosis of skin	0.586	0.413	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.586	0.413	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.586	0.413	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.586	0.413	0.000
L98.1 Factitial dermatitis	0.586	0.413	0.000
T79-T79 Certain early complications of trauma	0.586	0.414	0.000
T33-T35 Frostbite	0.586	0.414	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.586	0.414	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.586	0.414	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.586	0.414	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.586	0.414	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.586	0.414	0.000
T00-T07 Injuries involving multiple body regions	0.586	0.414	0.000
S10-S19 Injuries to the neck	0.586	0.414	0.000
F30-F39 Mood [affective] disorders	0.585	0.415	0.000
L60 Nail disorders	0.585	0.415	0.000
L81 Other disorders of pigmentation	0.585	0.415	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.584	0.416	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.584	0.416	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.584	0.416	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.584	0.416	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.584	0.416	0.000
M70-M79 Other soft tissue disorders	0.583	0.417	0.000
S80 Superficial injury of lower leg	0.583	0.417	0.000
S20-S29 Injuries to the thorax	0.582	0.417	0.000
L03.9 Cellulitis, unspecified	0.582	0.418	0.000
J18 Pneumonia, organism unspecified	0.581	0.419	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.581	0.419	0.000
L40-L45 Papulosquamous disorders	0.575	0.425	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.574	0.426	0.000
E13 Other specified diabetes mellitus	0.571	0.429	0.000
E12 Malnutrition-related diabetes mellitus	0.571	0.429	0.000
G56.0 Carpal tunnel syndrome	0.570	0.430	0.000
C15 Malignant neoplasm of oesophagus	0.568	0.432	0.000
C60-C63 Malignant neoplasms of male genital organs	0.566	0.434	0.000
L05 Pilonidal cyst	0.566	0.434	0.000
L04 Acute lymphadenitis	0.566	0.434	0.000
L01 Impetigo	0.566	0.434	0.000
L00 Staphylococcal scalded skin syndrome	0.566	0.434	0.000
S00.8 Superficial injury of other parts of head	0.564	0.436	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.560	0.440	0.000
C16 Malignant neoplasm of stomach	0.560	0.440	0.000
S06 Intracranial injury	0.556	0.443	0.000
E10.4 With neurological complications	0.554	0.446	0.000
G24 Dystonia	0.552	0.448	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.552	0.448	0.000
L03.3 Cellulitis of trunk	0.552	0.448	0.000
E67 Other hyperalimentation	0.551	0.449	0.000
E68 Sequelae of hyperalimentation	0.551	0.449	0.000
E65 Localised adiposity	0.551	0.449	0.000
Chapter XX External causes of morbidity and mortality	0.551	0.449	0.000
E10.9 Without complications	0.551	0.449	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.550	0.450	0.000
E11.4 With neurological complications	0.545	0.455	0.000
T78 Adverse effects, not elsewhere classified	0.545	0.455	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.543	0.457	0.000
E11.5 With peripheral circulatory complications	0.543	0.457	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.542	0.458	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.542	0.458	0.000
J18.1 Lobar pneumonia, unspecified	0.541	0.459	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.538	0.462	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.537	0.463	0.000
O04 Medical abortion	0.536	0.464	0.000
J33.8 Other polyp of sinus	0.535	0.465	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.535	0.465	0.000
S40-S49 Injuries to the shoulder and upper arm	0.534	0.465	0.000
O60-O75 Complications of labour and delivery	0.534	0.466	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.534	0.466	0.000
E14 Unspecified diabetes mellitus	0.534	0.466	0.000
G58 Other mononeuropathies	0.532	0.468	0.000
G54 Nerve root and plexus disorders	0.532	0.468	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.532	0.468	0.000
G52 Disorders of other cranial nerves	0.532	0.468	0.000
G50 Disorders of trigeminal nerve	0.532	0.468	0.000
C51-C58 Malignant neoplasms of female genital organs	0.531	0.468	0.000
S02 Fracture of skull and facial bones	0.531	0.469	0.000
L72.1 Trichilemmal cyst	0.530	0.470	0.000
C44.6 Skin of upper limb, including shoulder	0.530	0.470	0.000
E10.3 With ophthalmic complications	0.529	0.470	0.000
M79.6 Pain in limb	0.529	0.471	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.528	0.472	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.528	0.472	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.527	0.473	0.000
S08 Traumatic amputation of part of head	0.526	0.474	0.000
S07 Crushing injury of head	0.526	0.474	0.000
S05 Injury of eye and orbit	0.526	0.474	0.000
S04 Injury of cranial nerves	0.526	0.474	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.526	0.474	0.000
C79 Secondary malignant neoplasm of other sites	0.525	0.475	0.000
L75 Apocrine sweat disorders	0.525	0.475	0.000
L74 Eccrine sweat disorders	0.525	0.475	0.000
L73 Other follicular disorders	0.525	0.475	0.000
L71 Rosacea	0.525	0.475	0.000
L70 Acne	0.525	0.475	0.000
L68 Hypertrichosis	0.525	0.475	0.000
L67 Hair colour and hair shaft abnormalities	0.525	0.475	0.000
L66 Cicatricial alopecia [scarring hair loss]	0.525	0.475	0.000
L65 Other nonscarring hair loss	0.525	0.475	0.000
L64 Androgenic alopecia	0.525	0.475	0.000
L63 Alopecia areata	0.525	0.475	0.000
L62 Nail disorders in diseases classified elsewhere	0.525	0.475	0.000
Chapter XIV Diseases of the genitourinary system	0.525	0.475	0.000
G20 Parkinson's disease	0.522	0.478	0.000
L53 Other erythematous conditions	0.522	0.478	0.000
T93 Sequelae of injuries of lower limb	0.522	0.478	0.000
J35 Chronic diseases of tonsils and adenoids	0.521	0.479	0.000
E11.8 With unspecified complications	0.521	0.479	0.000
E11.7 With multiple complications	0.521	0.479	0.000
E11.6 With other specified complications	0.521	0.479	0.000
E11.2 With renal complications	0.521	0.479	0.000
E11.1 With ketoacidosis	0.521	0.479	0.000
E11.0 With coma	0.521	0.479	0.000
C64-C68 Malignant neoplasms of urinary tract	0.521	0.479	0.000
F99-F99 Unspecified mental disorder	0.520	0.480	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.520	0.480	0.000
F80-F89 Disorders of psychological development	0.520	0.480	0.000
F70-F79 Mental retardation	0.520	0.480	0.000
F60-F69 Disorders of adult personality and behaviour	0.520	0.480	0.000
C44.4 Skin of scalp and neck	0.519	0.481	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.518	0.482	0.000
E00-E07 Disorders of thyroid gland	0.518	0.482	0.000
E16.2 Hypoglycaemia, unspecified	0.517	0.483	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.516	0.484	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.516	0.484	0.000
M10 Gout	0.515	0.485	0.000
S89 Other and unspecified injuries of lower leg	0.514	0.486	0.000
S88 Traumatic amputation of lower leg	0.514	0.486	0.000
S87 Crushing injury of lower leg	0.514	0.486	0.000
S86 Injury of muscle and tendon at lower leg level	0.514	0.486	0.000
S85 Injury of blood vessels at lower leg level	0.514	0.486	0.000
S84 Injury of nerves at lower leg level	0.514	0.486	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.514	0.486	0.000
S81 Open wound of lower leg	0.514	0.486	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.513	0.487	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.512	0.487	0.000
C25 Malignant neoplasm of pancreas	0.512	0.487	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.512	0.487	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.512	0.487	0.000
C21 Malignant neoplasm of anus and anal canal	0.512	0.487	0.000
C17 Malignant neoplasm of small intestine	0.512	0.487	0.000
C23 Malignant neoplasm of gallbladder	0.512	0.487	0.000
G57 Mononeuropathies of lower limb	0.511	0.489	0.000
N17-N19 Renal failure	0.511	0.489	0.000
S50-S59 Injuries to the elbow and forearm	0.509	0.490	0.001
D05 Carcinoma in situ of breast	0.509	0.491	0.000
J69 Pneumonitis due to solids and liquids	0.509	0.491	0.000
C18.0 Caecum	0.509	0.491	0.000
G37 Other demyelinating diseases of central nervous system	0.509	0.491	0.000
G36 Other acute disseminated demyelination	0.509	0.491	0.000
O85-O92 Complications predominantly related to the puerperium	0.508	0.491	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.508	0.492	0.000
E66.1 Drug-induced obesity	0.508	0.492	0.000
E66.0 Obesity due to excess calories	0.508	0.492	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.508	0.492	0.000
E83 Disorders of mineral metabolism	0.508	0.492	0.000
T51 Toxic effect of alcohol	0.507	0.492	0.000
M79.66 Pain in limb (Lower leg)	0.507	0.493	0.000
Chapter VII Diseases of the eye and adnexa	0.507	0.493	0.000
S01.1 Open wound of eyelid and periocular area	0.506	0.494	0.000
S61 Open wound of wrist and hand	0.505	0.495	0.000
L03.8 Cellulitis of other sites	0.504	0.496	0.000
L03.2 Cellulitis of face	0.504	0.496	0.000
E15 Nondiabetic hypoglycaemic coma	0.503	0.497	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.503	0.497	0.000
E88 Other metabolic disorders	0.502	0.498	0.000
E85 Amyloidosis	0.502	0.498	0.000
E84 Cystic fibrosis	0.502	0.498	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.502	0.498	0.000
E79 Disorders of purine and pyrimidine metabolism	0.502	0.498	0.000
E77 Disorders of glycoprotein metabolism	0.502	0.498	0.000
E76 Disorders of glycosaminoglycan metabolism	0.502	0.498	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.502	0.498	0.000
E74 Other disorders of carbohydrate metabolism	0.502	0.498	0.000
E73 Lactose intolerance	0.502	0.498	0.000
E72 Other disorders of amino-acid metabolism	0.502	0.498	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.502	0.498	0.000
E70 Disorders of aromatic amino-acid metabolism	0.502	0.498	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.502	0.498	0.000
G56.2 Lesion of ulnar nerve	0.502	0.498	0.000
J36 Peritonsillar abscess	0.502	0.498	0.000
M65-M68 Disorders of synovium and tendon	0.501	0.498	0.000
Chapter I Certain infectious and parasitic diseases	0.501	0.499	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.501	0.499	0.000
S00.1 Contusion of eyelid and periocular area	0.500	0.499	0.000
O03 Spontaneous abortion	0.500	0.500	0.000
C43 Malignant melanoma of skin	0.500	0.500	0.000
J37 Chronic laryngitis and laryngotracheitis	0.499	0.501	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.498	0.502	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.497	0.503	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.497	0.503	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.495	0.505	0.000
M91-M94 Chondropathies	0.495	0.505	0.000
M86-M90 Other osteopathies	0.495	0.505	0.000
M60-M63 Disorders of muscles	0.495	0.505	0.000
M00-M03 Infectious arthropathies	0.495	0.505	0.000
H60-H62 Diseases of external ear	0.494	0.506	0.000
E10.8 With unspecified complications	0.494	0.506	0.000
E10.7 With multiple complications	0.494	0.506	0.000
E10.6 With other specified complications	0.494	0.506	0.000
E10.5 With peripheral circulatory complications	0.494	0.506	0.000
E10.2 With renal complications	0.494	0.506	0.000
E10.1 With ketoacidosis	0.494	0.506	0.000
E10.0 With coma	0.494	0.506	0.000
F32 Depressive episode	0.494	0.506	0.000
C18.4 Transverse colon	0.493	0.507	0.000
C44.2 Skin of ear and external auricular canal	0.493	0.507	0.000
C50 Malignant neoplasm of breast	0.493	0.507	0.000
G59.0 Diabetic mononeuropathy	0.493	0.507	0.000
F11 Mental and behavioural disorders due to use of opioids	0.492	0.508	0.000
D10-D36 Benign neoplasms	0.491	0.509	0.000
M40-M43 Deforming dorsopathies	0.490	0.510	0.000
M80-M85 Disorders of bone density and structure	0.490	0.510	0.000
J00-J06 Acute upper respiratory infections	0.489	0.511	0.000
O02 Other abnormal products of conception	0.489	0.511	0.000
G25 Other extrapyramidal and movement disorders	0.489	0.511	0.000
G23 Other degenerative diseases of basal ganglia	0.489	0.511	0.000
G21 Secondary Parkinsonism	0.489	0.511	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.489	0.511	0.000
G22 Parkinsonism in diseases classified elsewhere	0.489	0.511	0.000
S68 Traumatic amputation of wrist and hand	0.489	0.511	0.000
E66.8 Other obesity	0.487	0.513	0.000
D41.4 Bladder	0.486	0.514	0.000
N17 Acute renal failure	0.485	0.515	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.485	0.515	0.000
L58 Radiodermatitis	0.485	0.515	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.485	0.515	0.000
L55 Sunburn	0.485	0.515	0.000
L90 Atrophic disorders of skin	0.485	0.515	0.000
S82.5 Fracture of medial malleolus	0.484	0.516	0.000
J33.1 Polypoid sinus degeneration	0.484	0.516	0.000
L85.9 Epidermal thickening, unspecified	0.483	0.517	0.000
S01.8 Open wound of other parts of head	0.483	0.517	0.000
G51.0 Bell's palsy	0.483	0.517	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.481	0.519	0.000
S64 Injury of nerves at wrist and hand level	0.481	0.519	0.000
S80.8 Other superficial injuries of lower leg	0.481	0.519	0.000
S92 Fracture of foot, except ankle	0.481	0.519	0.000
L60.0 Ingrowing nail	0.480	0.520	0.000
G61 Inflammatory polyneuropathy	0.479	0.521	0.000
C73 Malignant neoplasm of thyroid gland	0.479	0.521	0.000
J30 Vasomotor and allergic rhinitis	0.478	0.522	0.000
L54 Erythema in diseases classified elsewhere	0.477	0.523	0.000
L51 Erythema multiforme	0.477	0.523	0.000
L50 Urticaria	0.477	0.523	0.000
L52 Erythema nodosum	0.477	0.523	0.000
M50-M54 Other dorsopathies	0.477	0.523	0.000
J34 Other disorders of nose and nasal sinuses	0.476	0.524	0.000
S82.6 Fracture of lateral malleolus	0.476	0.524	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.475	0.525	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.475	0.525	0.000
D46 Myelodysplastic syndromes	0.475	0.525	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.475	0.525	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.475	0.525	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.475	0.525	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.475	0.525	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.475	0.525	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.475	0.525	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.475	0.525	0.000
G47 Sleep disorders	0.475	0.525	0.000
S69 Other and unspecified injuries of wrist and hand	0.474	0.526	0.000
S67 Crushing injury of wrist and hand	0.474	0.526	0.000
S65 Injury of blood vessels at wrist and hand level	0.474	0.526	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.474	0.526	0.000
S60 Superficial injury of wrist and hand	0.474	0.526	0.000
M45-M49 Spondylopathies	0.474	0.526	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.474	0.526	0.000
T75 Effects of other external causes	0.472	0.528	0.000
T74 Maltreatment syndromes	0.472	0.528	0.000
T73 Effects of other deprivation	0.472	0.528	0.000
T70 Effects of air pressure and water pressure	0.472	0.528	0.000
T69 Other effects of reduced temperature	0.472	0.528	0.000
T67 Effects of heat and light	0.472	0.528	0.000
T71 Asphyxiation	0.472	0.528	0.000
T68 Hypothermia	0.472	0.528	0.000
T66 Unspecified effects of radiation	0.472	0.528	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.472	0.528	0.000
S82.8 Fractures of other parts of lower leg	0.472	0.528	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.471	0.529	0.000
J39 Other diseases of upper respiratory tract	0.470	0.530	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.469	0.531	0.000
O80-O84 Delivery	0.469	0.531	0.000
J17 Pneumonia in diseases classified elsewhere	0.468	0.532	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.468	0.532	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.468	0.532	0.000
J12 Viral pneumonia, not elsewhere classified	0.468	0.532	0.000
J11 Influenza, virus not identified	0.468	0.532	0.000
J10 Influenza due to identified influenza virus	0.468	0.532	0.000
J14 Pneumonia due to Haemophilus influenzae	0.468	0.532	0.000
J09 Influenza due to certain identified influenza virus	0.468	0.532	0.000
O04.9 Complete or unspecified, without complication	0.468	0.532	0.000
N17.9 Acute renal failure, unspecified	0.468	0.532	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.467	0.533	0.000
E34 Other endocrine disorders	0.467	0.533	0.000
E32 Diseases of thymus	0.467	0.533	0.000
E31 Polyglandular dysfunction	0.467	0.533	0.000
E30 Disorders of puberty, not elsewhere classified	0.467	0.533	0.000
E29 Testicular dysfunction	0.467	0.533	0.000
E28 Ovarian dysfunction	0.467	0.533	0.000
E27 Other disorders of adrenal gland	0.467	0.533	0.000
E26 Hyperaldosteronism	0.467	0.533	0.000
E25 Adrenogenital disorders	0.467	0.533	0.000
E24 Cushing's syndrome	0.467	0.533	0.000
E23 Hypofunction and other disorders of pituitary gland	0.467	0.533	0.000
E22 Hyperfunction of pituitary gland	0.467	0.533	0.000
E20 Hypoparathyroidism	0.467	0.533	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.467	0.533	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.466	0.533	0.000
G56.8 Other mononeuropathies of upper limb	0.466	0.533	0.000
G56.4 Causalgia	0.466	0.533	0.000
G56.3 Lesion of radial nerve	0.466	0.533	0.000
G56.1 Other lesions of median nerve	0.466	0.533	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.466	0.534	0.000
J18.0 Bronchopneumonia, unspecified	0.465	0.535	0.000
D45 Polycythaemia vera	0.464	0.535	0.000
M15-M19 Arthrosis	0.464	0.536	0.000
S62 Fracture at wrist and hand level	0.463	0.537	0.000
M10.9 Gout, unspecified	0.463	0.537	0.000
T98 Sequelae of other and unspecified effects of external causes	0.463	0.537	0.000
T95 Sequelae of burns, corrosions and frostbite	0.463	0.537	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.463	0.537	0.000
T92 Sequelae of injuries of upper limb	0.463	0.537	0.000
T91 Sequelae of injuries of neck and trunk	0.463	0.537	0.000
T90 Sequelae of injuries of head	0.463	0.537	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.463	0.537	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.463	0.537	0.000
C18.2 Ascending colon	0.462	0.538	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.462	0.538	0.000
S72 Fracture of femur	0.461	0.539	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.460	0.540	0.000
C44.8 Overlapping lesion of skin	0.460	0.540	0.000
C44.0 Skin of lip	0.460	0.540	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.460	0.540	0.000
J32 Chronic sinusitis	0.460	0.540	0.000
S00.7 Multiple superficial injuries of head	0.460	0.540	0.000
S00.5 Superficial injury of lip and oral cavity	0.460	0.540	0.000
S00.4 Superficial injury of ear	0.460	0.540	0.000
S00.3 Superficial injury of nose	0.460	0.540	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.460	0.540	0.000
S00.0 Superficial injury of scalp	0.460	0.540	0.000
G24.9 Dystonia, unspecified	0.459	0.541	0.000
D09 Carcinoma in situ of other and unspecified sites	0.459	0.541	0.000
D04 Carcinoma in situ of skin	0.459	0.541	0.000
D03 Melanoma in situ	0.459	0.541	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.459	0.541	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.459	0.541	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.459	0.541	0.000
L89.1 Stage II decubitus ulcer	0.459	0.541	0.000
C91 Lymphoid leukaemia	0.458	0.542	0.000
L85.8 Other specified epidermal thickening	0.458	0.542	0.000
L85.3 Xerosis cutis	0.458	0.542	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.458	0.542	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.458	0.542	0.000
L85.0 Acquired ichthyosis	0.458	0.542	0.000
T65 Toxic effect of other and unspecified substances	0.457	0.543	0.000
T63 Toxic effect of contact with venomous animals	0.457	0.543	0.000
T62 Toxic effect of other noxious substances eaten as food	0.457	0.543	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.457	0.543	0.000
T60 Toxic effect of pesticides	0.457	0.543	0.000
T59 Toxic effect of other gases, fumes and vapours	0.457	0.543	0.000
T57 Toxic effect of other inorganic substances	0.457	0.543	0.000
T56 Toxic effect of metals	0.457	0.543	0.000
T54 Toxic effect of corrosive substances	0.457	0.543	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.457	0.543	0.000
T52 Toxic effect of organic solvents	0.457	0.543	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.457	0.543	0.000
T58 Toxic effect of carbon monoxide	0.457	0.543	0.000
T55 Toxic effect of soaps and detergents	0.457	0.543	0.000
S09 Other and unspecified injuries of head	0.457	0.543	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.457	0.543	0.000
N18 Chronic renal failure	0.456	0.544	0.000
C18.9 Colon, unspecified	0.456	0.544	0.000
F10.0 Acute intoxication	0.456	0.544	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.455	0.545	0.000
D06 Carcinoma in situ of cervix uteri	0.453	0.547	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.453	0.547	0.000
O07 Failed attempted abortion	0.453	0.547	0.000
O06 Unspecified abortion	0.453	0.547	0.000
O05 Other abortion	0.453	0.547	0.000
O01 Hydatidiform mole	0.453	0.547	0.000
O00 Ectopic pregnancy	0.453	0.547	0.000
M06 Other rheumatoid arthritis	0.452	0.547	0.000
C80 Malignant neoplasm without specification of site	0.452	0.548	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.452	0.548	0.000
J33.0 Polyp of nasal cavity	0.452	0.548	0.000
J95-J99 Other diseases of the respiratory system	0.451	0.548	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.451	0.549	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.451	0.549	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.451	0.549	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.451	0.549	0.000
C15.9 Oesophagus, unspecified	0.451	0.549	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.450	0.549	0.000
C16.0 Cardia	0.449	0.551	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.448	0.552	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations