TreeWAS – Variant ID: rs1509911

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.092	0.908	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.087	0.913	0.000
T36 Poisoning by systemic antibiotics	0.085	0.915	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.919	0.081
T40.2 Other opioids	0.079	0.921	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.078	0.922	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.077	0.923	0.000
T40.4 Other synthetic narcotics	0.076	0.924	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.074	0.926	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.073	0.927	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.073	0.927	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.073	0.927	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.073	0.927	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.071	0.929	0.000
T36.8 Other systemic antibiotics	0.071	0.929	0.000
T36.0 Penicillins	0.071	0.929	0.000
T46.1 Calcium-channel blockers	0.070	0.930	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.069	0.931	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.066	0.934	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.066	0.934	0.000
T36.3 Macrolides	0.066	0.934	0.000
T36.4 Tetracyclines	0.065	0.935	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.064	0.936	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.064	0.936	0.000
T39.1 4-Aminophenol derivatives	0.064	0.936	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.064	0.936	0.000
T40.6 Other and unspecified narcotics	0.063	0.937	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.063	0.937	0.000
T40.8 Lysergide [LSD]	0.063	0.937	0.000
T40.7 Cannabis (derivatives)	0.063	0.937	0.000
T40.5 Cocaine	0.063	0.937	0.000
T40.3 Methadone	0.063	0.937	0.000
T40.1 Heroin	0.063	0.937	0.000
T40.0 Opium	0.063	0.937	0.000
T45.5 Anticoagulants	0.062	0.938	0.000
T45.0 Antiallergic and antiemetic drugs	0.062	0.938	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.062	0.938	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.061	0.939	0.000
T36.9 Systemic antibiotic, unspecified	0.061	0.939	0.000
T36.7 Antifungal antibiotics, systemically used	0.061	0.939	0.000
T36.6 Rifamycins	0.061	0.939	0.000
T36.5 Aminoglycosides	0.061	0.939	0.000
T36.2 Chloramphenicol group	0.061	0.939	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.061	0.939	0.000
T47.2 Stimulant laxatives	0.061	0.939	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.060	0.940	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.060	0.940	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.060	0.940	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.059	0.941	0.000
T47.6 Antidiarrhoeal drugs	0.058	0.942	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.058	0.942	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.058	0.942	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.057	0.943	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.057	0.943	0.000
T51 Toxic effect of alcohol	0.057	0.943	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.057	0.943	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.056	0.944	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.056	0.944	0.000
T46.7 Peripheral vasodilators	0.056	0.944	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.056	0.944	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.056	0.944	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.056	0.944	0.000
T43.2 Other and unspecified antidepressants	0.056	0.944	0.000
T90 Sequelae of injuries of head	0.056	0.944	0.000
T90.4 Sequelae of injury of eye and orbit	0.056	0.944	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.055	0.945	0.000
T45.8 Other primarily systemic and haematological agents	0.055	0.945	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.055	0.945	0.000
T45.6 Fibrinolysis-affecting drugs	0.055	0.945	0.000
T45.4 Iron and its compounds	0.055	0.945	0.000
T45.3 Enzymes, not elsewhere classified	0.055	0.945	0.000
T51.0 Ethanol	0.055	0.945	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.055	0.945	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.055	0.945	0.000
T50.4 Drugs affecting uric acid metabolism	0.055	0.945	0.000
S06 Intracranial injury	0.055	0.945	0.000
S00-S09 Injuries to the head	0.054	0.946	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.054	0.946	0.000
T39.4 Antirheumatics, not elsewhere classified	0.053	0.947	0.000
T39.2 Pyrazolone derivatives	0.053	0.947	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.053	0.947	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.053	0.947	0.000
T47.7 Emetics	0.053	0.947	0.000
T47.5 Digestants	0.053	0.947	0.000
T47.4 Other laxatives	0.053	0.947	0.000
T47.3 Saline and osmotic laxatives	0.053	0.947	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.053	0.947	0.000
T48.5 Anti-common-cold drugs	0.053	0.947	0.000
T48.4 Expectorants	0.053	0.947	0.000
T48.3 Antitussives	0.053	0.947	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.053	0.947	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.053	0.947	0.000
T48.0 Oxytocic drugs	0.053	0.947	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.053	0.947	0.000
T37.5 Antiviral drugs	0.053	0.947	0.000
T37.4 Anthelminthics	0.053	0.947	0.000
T37.3 Other antiprotozoal drugs	0.053	0.947	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.053	0.947	0.000
T37.1 Antimycobacterial drugs	0.053	0.947	0.000
T37.0 Sulphonamides	0.053	0.947	0.000
T42.1 Iminostilbenes	0.053	0.947	0.000
T50.7 Analeptics and opioid receptor antagonists	0.052	0.947	0.000
T50.5 Appetite depressants	0.052	0.947	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.052	0.947	0.000
T50.1 Loop [high-ceiling] diuretics	0.052	0.947	0.000
T50.0 Mineralocorticoids and their antagonists	0.052	0.947	0.000
S06.5 Traumatic subdural haemorrhage	0.052	0.948	0.000
T63 Toxic effect of contact with venomous animals	0.052	0.948	0.000
T45.2 Vitamins, not elsewhere classified	0.052	0.948	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.052	0.948	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.051	0.949	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.051	0.949	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.051	0.949	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.051	0.949	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.051	0.949	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.051	0.949	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.051	0.949	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.051	0.949	0.000
T44.0 Anticholinesterase agents	0.051	0.949	0.000
S32 Fracture of lumbar spine and pelvis	0.051	0.949	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.051	0.949	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.051	0.949	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.050	0.949	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.050	0.950	0.000
T92 Sequelae of injuries of upper limb	0.050	0.950	0.000
T90.8 Sequelae of other specified injuries of head	0.050	0.950	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.050	0.950	0.000
S80-S89 Injuries to the knee and lower leg	0.050	0.950	0.000
T43.9 Psychotropic drug, unspecified	0.049	0.951	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.049	0.951	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.049	0.951	0.000
T43.6 Psychostimulants with abuse potential	0.049	0.951	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.049	0.951	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.049	0.951	0.000
S09 Other and unspecified injuries of head	0.049	0.951	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.048	0.952	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.048	0.952	0.000
T41.5 Therapeutic gases	0.047	0.952	0.000
T41.4 Anaesthetic, unspecified	0.047	0.952	0.000
T41.3 Local anaesthetics	0.047	0.952	0.000
T41.2 Other and unspecified general anaesthetics	0.047	0.952	0.000
T41.1 Intravenous anaesthetics	0.047	0.952	0.000
T41.0 Inhaled anaesthetics	0.047	0.952	0.000
T49.9 Topical agent, unspecified	0.047	0.952	0.000
T49.8 Other topical agents	0.047	0.952	0.000
T49.7 Dental drugs, topically applied	0.047	0.952	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.047	0.952	0.000
T49.5 Ophthalmological drugs and preparations	0.047	0.952	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.047	0.952	0.000
T49.3 Emollients, demulcents and protectants	0.047	0.952	0.000
T49.2 Local astringents and local detergents	0.047	0.952	0.000
T49.1 Antipruritics	0.047	0.952	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.047	0.952	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.047	0.952	0.000
T59 Toxic effect of other gases, fumes and vapours	0.047	0.952	0.000
S30.1 Contusion of abdominal wall	0.047	0.953	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.047	0.953	0.000
T63.4 Venom of other arthropods	0.047	0.953	0.000
T47.0 Histamine H(2)-receptor antagonists	0.047	0.953	0.000
S36 Injury of intra-abdominal organs	0.047	0.953	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.046	0.953	0.000
T50.8 Diagnostic agents	0.046	0.953	0.000
T38.9 Other and unspecified hormone antagonists	0.046	0.954	0.000
T38.7 Androgens and anabolic congeners	0.046	0.954	0.000
T38.5 Other oestrogens and progestogens	0.046	0.954	0.000
T38.4 Oral contraceptives	0.046	0.954	0.000
T38.2 Antithyroid drugs	0.046	0.954	0.000
T38.0 Glucocorticoids and synthetic analogues	0.046	0.954	0.000
M86-M90 Other osteopathies	0.046	0.954	0.000
T92.1 Sequelae of fracture of arm	0.046	0.954	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.046	0.954	0.000
T98 Sequelae of other and unspecified effects of external causes	0.045	0.955	0.000
M87 Osteonecrosis	0.045	0.955	0.000
M89 Other disorders of bone	0.045	0.955	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.045	0.955	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.045	0.955	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.045	0.955	0.000
T52 Toxic effect of organic solvents	0.045	0.955	0.000
M84 Disorders of continuity of bone	0.045	0.955	0.000
T13 Other injuries of lower limb, level unspecified	0.045	0.955	0.000
S06.0 Concussion	0.045	0.955	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.044	0.956	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.044	0.956	0.000
S86 Injury of muscle and tendon at lower leg level	0.044	0.956	0.000
T58 Toxic effect of carbon monoxide	0.044	0.956	0.000
T54 Toxic effect of corrosive substances	0.044	0.956	0.000
S06.1 Traumatic cerebral oedema	0.043	0.956	0.000
T38.1 Thyroid hormones and substitutes	0.043	0.957	0.000
T65 Toxic effect of other and unspecified substances	0.043	0.957	0.000
M89.0 Algoneurodystrophy	0.043	0.957	0.000
T91 Sequelae of injuries of neck and trunk	0.043	0.957	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.043	0.957	0.000
T92.0 Sequelae of open wound of upper limb	0.043	0.957	0.000
S06.2 Diffuse brain injury	0.043	0.957	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.043	0.957	0.000
T00-T07 Injuries involving multiple body regions	0.043	0.957	0.000
M87.9 Osteonecrosis, unspecified	0.043	0.957	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.043	0.957	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.043	0.957	0.000
S09.9 Unspecified injury of head	0.043	0.957	0.000
S32.4 Fracture of acetabulum	0.042	0.958	0.000
T51.9 Alcohol, unspecified	0.042	0.958	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.042	0.958	0.000
T60 Toxic effect of pesticides	0.042	0.958	0.000
T57 Toxic effect of other inorganic substances	0.042	0.958	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.042	0.958	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.042	0.958	0.000
T55 Toxic effect of soaps and detergents	0.042	0.958	0.000
S37 Injury of urinary and pelvic organs	0.042	0.958	0.000
S60-S69 Injuries to the wrist and hand	0.042	0.958	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.042	0.958	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.042	0.958	0.000
T42.3 Barbiturates	0.042	0.958	0.000
T42.2 Succinimides and oxazolidinediones	0.042	0.958	0.000
S03.1 Dislocation of septal cartilage of nose	0.042	0.958	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.042	0.958	0.000
M89.8 Other specified disorders of bone	0.042	0.958	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.041	0.959	0.000
S67 Crushing injury of wrist and hand	0.041	0.959	0.000
S60 Superficial injury of wrist and hand	0.041	0.959	0.000
M86 Osteomyelitis	0.041	0.959	0.000
T62 Toxic effect of other noxious substances eaten as food	0.041	0.959	0.000
T90.1 Sequelae of open wound of head	0.041	0.959	0.000
T09 Other injuries of spine and trunk, level unspecified	0.041	0.959	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.041	0.959	0.000
T42.0 Hydantoin derivatives	0.041	0.959	0.000
T51.8 Other alcohols	0.041	0.959	0.000
T51.3 Fusel oil	0.041	0.959	0.000
T51.2 2-Propanol	0.041	0.959	0.000
T51.1 Methanol	0.041	0.959	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.041	0.959	0.000
T33-T35 Frostbite	0.041	0.959	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.041	0.959	0.000
S36.1 Injury of liver or gallbladder	0.041	0.959	0.000
M80-M85 Disorders of bone density and structure	0.041	0.959	0.000
T59.9 Gases, fumes and vapours, unspecified	0.041	0.959	0.000
T90.3 Sequelae of injury of cranial nerves	0.040	0.960	0.000
M87.8 Other osteonecrosis	0.040	0.960	0.000
S81 Open wound of lower leg	0.040	0.960	0.000
S03.2 Dislocation of tooth	0.040	0.960	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.040	0.960	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.040	0.960	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.040	0.960	0.000
T93 Sequelae of injuries of lower limb	0.040	0.960	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.040	0.960	0.000
S06.7 Intracranial injury with prolonged coma	0.040	0.960	0.000
M84.4 Pathological fracture, not elsewhere classified	0.040	0.960	0.000
T90.0 Sequelae of superficial injury of head	0.039	0.960	0.000
S03.0 Dislocation of jaw	0.039	0.961	0.000
S80 Superficial injury of lower leg	0.039	0.961	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.039	0.961	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.039	0.961	0.000
S08 Traumatic amputation of part of head	0.039	0.961	0.000
S07 Crushing injury of head	0.039	0.961	0.000
S04 Injury of cranial nerves	0.039	0.961	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.039	0.961	0.000
T56 Toxic effect of metals	0.039	0.961	0.000
S02 Fracture of skull and facial bones	0.039	0.961	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.039	0.961	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.039	0.961	0.000
S81.8 Open wound of other parts of lower leg	0.039	0.961	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.038	0.961	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.038	0.962	0.000
S32.1 Fracture of sacrum	0.038	0.962	0.000
M84.3 Stress fracture, not elsewhere classified	0.038	0.962	0.000
S89 Other and unspecified injuries of lower leg	0.038	0.962	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.038	0.962	0.000
T63.8 Toxic effect of contact with other venomous animals	0.038	0.962	0.000
T63.6 Toxic effect of contact with other marine animals	0.038	0.962	0.000
T63.5 Toxic effect of contact with fish	0.038	0.962	0.000
T63.3 Venom of spider	0.038	0.962	0.000
T63.2 Venom of scorpion	0.038	0.962	0.000
T63.1 Venom of other reptiles	0.038	0.962	0.000
T63.0 Snake venom	0.038	0.962	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.038	0.962	0.000
S84 Injury of nerves at lower leg level	0.037	0.962	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.038	0.962	0.000
S09.7 Multiple injuries of head	0.037	0.963	0.000
T90.5 Sequelae of intracranial injury	0.037	0.963	0.000
S06.00 Concussion (without open intracranial wound)	0.037	0.963	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.037	0.963	0.000
S32.2 Fracture of coccyx	0.037	0.963	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.037	0.963	0.000
M89.04 Algoneurodystrophy (Hand)	0.037	0.963	0.000
S06.8 Other intracranial injuries	0.037	0.963	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.037	0.963	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.037	0.963	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.037	0.963	0.000
S32.3 Fracture of ilium	0.037	0.963	0.000
S06.9 Intracranial injury, unspecified	0.036	0.963	0.000
T02 Fractures involving multiple body regions	0.036	0.963	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.037	0.963	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.036	0.963	0.000
S34.1 Other injury of lumbar spinal cord	0.036	0.963	0.000
S06.3 Focal brain injury	0.036	0.964	0.000
S69 Other and unspecified injuries of wrist and hand	0.036	0.964	0.000
S02.1 Fracture of base of skull	0.036	0.964	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.036	0.964	0.000
S32.40 Fracture of acetabulum (closed)	0.036	0.964	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.036	0.964	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.036	0.964	0.000
S36.8 Injury of other intra-abdominal organs	0.036	0.964	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.036	0.964	0.000
S60.0 Contusion of finger(s) without damage to nail	0.036	0.964	0.000
S88 Traumatic amputation of lower leg	0.036	0.964	0.000
S87 Crushing injury of lower leg	0.036	0.964	0.000
S85 Injury of blood vessels at lower leg level	0.036	0.964	0.000
M91-M94 Chondropathies	0.036	0.964	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.036	0.964	0.000
T11 Other injuries of upper limb, level unspecified	0.036	0.964	0.000
M79.8 Other specified soft tissue disorders	0.036	0.964	0.000
T91.3 Sequelae of injury of spinal cord	0.036	0.964	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.035	0.964	0.000
S03.4 Sprain and strain of jaw	0.035	0.964	0.000
S03.3 Dislocation of other and unspecified parts of head	0.035	0.964	0.000
M84.0 Malunion of fracture	0.036	0.964	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.035	0.965	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.035	0.965	0.000
M25.76 Osteophyte (Lower leg)	0.035	0.965	0.000
T52.8 Other organic solvents	0.035	0.965	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.035	0.965	0.000
T79-T79 Certain early complications of trauma	0.035	0.965	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.035	0.965	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.035	0.965	0.000
T12 Fracture of lower limb, level unspecified	0.035	0.965	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.035	0.965	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.035	0.965	0.000
T10 Fracture of upper limb, level unspecified	0.035	0.965	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.035	0.965	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.035	0.965	0.000
T08 Fracture of spine, level unspecified	0.035	0.965	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.035	0.965	0.000
S09.2 Traumatic rupture of ear drum	0.035	0.965	0.000
S09.1 Injury of muscle and tendon of head	0.035	0.965	0.000
M86.6 Other chronic osteomyelitis	0.035	0.965	0.000
S06.4 Epidural haemorrhage	0.035	0.965	0.000
S09.8 Other specified injuries of head	0.035	0.965	0.000
T09.3 Injury of spinal cord, level unspecified	0.035	0.965	0.000
S32.5 Fracture of pubis	0.035	0.965	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.035	0.965	0.000
S60.2 Contusion of other parts of wrist and hand	0.035	0.965	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.035	0.965	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.035	0.965	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.034	0.965	0.000
M84.2 Delayed union of fracture	0.034	0.966	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.034	0.966	0.000
S02.10 Fracture of base of skull (closed)	0.034	0.966	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.034	0.966	0.000
T59.7 Carbon dioxide	0.034	0.966	0.000
T59.6 Hydrogen sulphide	0.034	0.966	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.034	0.966	0.000
T59.4 Chlorine gas	0.034	0.966	0.000
T59.3 Lachrymogenic gas	0.034	0.966	0.000
T59.2 Formaldehyde	0.034	0.966	0.000
T59.1 Sulphur dioxide	0.034	0.966	0.000
T59.0 Nitrogen oxides	0.034	0.966	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.034	0.966	0.000
M93 Other osteochondropathies	0.034	0.966	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.034	0.966	0.000
T93.1 Sequelae of fracture of femur	0.034	0.966	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.034	0.966	0.000
M87.86 Other osteonecrosis (Lower leg)	0.034	0.966	0.000
M70-M79 Other soft tissue disorders	0.034	0.966	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.034	0.966	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.034	0.966	0.000
S37.0 Injury of kidney	0.034	0.966	0.000
M82 Osteoporosis in diseases classified elsewhere	0.034	0.966	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.034	0.966	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.034	0.966	0.000
S36.7 Injury of multiple intra-abdominal organs	0.034	0.966	0.000
S36.6 Injury of rectum	0.034	0.966	0.000
S36.5 Injury of colon	0.034	0.966	0.000
S36.4 Injury of small intestine	0.034	0.966	0.000
S36.3 Injury of stomach	0.034	0.966	0.000
S36.2 Injury of pancreas	0.034	0.966	0.000
M80 Osteoporosis with pathological fracture	0.034	0.966	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.034	0.966	0.000
M87.1 Osteonecrosis due to drugs	0.033	0.966	0.000
M93.9 Osteochondropathy, unspecified	0.033	0.966	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.033	0.966	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.033	0.967	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.033	0.967	0.000
M89.5 Osteolysis	0.033	0.967	0.000
T95 Sequelae of burns, corrosions and frostbite	0.033	0.967	0.000
M89.84 Other specified disorders of bone (Hand)	0.033	0.967	0.000
T54.9 Corrosive substance, unspecified	0.033	0.967	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.033	0.967	0.000
S60.1 Contusion of finger(s) with damage to nail	0.033	0.967	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.033	0.967	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.033	0.967	0.000
T39.0 Salicylates	0.033	0.967	0.000
T09.0 Superficial injury of trunk, level unspecified	0.033	0.967	0.000
T98.2 Sequelae of certain early complications of trauma	0.033	0.967	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.033	0.967	0.000
M87.3 Other secondary osteonecrosis	0.033	0.967	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.033	0.967	0.000
M89.6 Osteopathy after poliomyelitis	0.033	0.967	0.000
M89.2 Other disorders of bone development and growth	0.033	0.967	0.000
M89.1 Epiphyseal arrest	0.033	0.967	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.033	0.967	0.000
T52.9 Organic solvent, unspecified	0.032	0.967	0.000
T52.4 Ketones	0.032	0.967	0.000
T52.3 Glycols	0.032	0.967	0.000
T52.2 Homologues of benzene	0.032	0.967	0.000
T52.1 Benzene	0.032	0.967	0.000
T52.0 Petroleum products	0.032	0.967	0.000
M84.9 Disorder of continuity of bone, unspecified	0.032	0.967	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.032	0.967	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.032	0.967	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.032	0.967	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.032	0.967	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.032	0.967	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.032	0.967	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.032	0.967	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.032	0.968	0.000
T65.9 Toxic effect of unspecified substance	0.032	0.968	0.000
T66-T78 Other and unspecified effects of external causes	0.032	0.968	0.000
S06.01 Concussion (with open intracranial wound)	0.032	0.968	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.032	0.968	0.000
T59.8 Other specified gases, fumes and vapours	0.032	0.968	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.032	0.968	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.032	0.968	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.032	0.968	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.032	0.968	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.032	0.968	0.000
S34.4 Injury of lumbosacral plexus	0.032	0.968	0.000
S34.3 Injury of cauda equina	0.032	0.968	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.032	0.968	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.032	0.968	0.000
M72 Fibroblastic disorders	0.032	0.968	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.032	0.968	0.000
T91.1 Sequelae of fracture of spine	0.032	0.968	0.000
M90 Osteopathies in diseases classified elsewhere	0.032	0.968	0.000
S86.0 Injury of Achilles tendon	0.032	0.968	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.032	0.968	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.032	0.968	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.032	0.968	0.000
T54.2 Corrosive acids and acid-like substances	0.032	0.968	0.000
T54.1 Other corrosive organic compounds	0.032	0.968	0.000
T54.0 Phenol and phenol homologues	0.032	0.968	0.000
M60-M63 Disorders of muscles	0.032	0.968	0.000
T93.0 Sequelae of open wound of lower limb	0.031	0.968	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.031	0.969	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.031	0.969	0.000
T65.8 Toxic effect of other specified substances	0.031	0.969	0.000
T65.6 Paints and dyes, not elsewhere classified	0.031	0.969	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.031	0.969	0.000
T65.4 Carbon disulphide	0.031	0.969	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.031	0.969	0.000
T65.2 Tobacco and nicotine	0.031	0.969	0.000
T65.1 Strychnine and its salts	0.031	0.969	0.000
T65.0 Cyanides	0.031	0.969	0.000
M89.08 Algoneurodystrophy (Other)	0.031	0.969	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.031	0.969	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.031	0.969	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.031	0.969	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.031	0.969	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.031	0.969	0.000
M86.9 Osteomyelitis, unspecified	0.031	0.969	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.031	0.969	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.031	0.969	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.031	0.969	0.000
M87.2 Osteonecrosis due to previous trauma	0.031	0.969	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.031	0.969	0.000
A08 Viral and other specified intestinal infections	0.000	0.969	0.031
T06 Other injuries involving multiple body regions, not elsewhere classified	0.031	0.969	0.000
T05 Traumatic amputations involving multiple body regions	0.031	0.969	0.000
T04 Crushing injuries involving multiple body regions	0.031	0.969	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.031	0.969	0.000
T07 Unspecified multiple injuries	0.031	0.969	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.031	0.969	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.031	0.969	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.031	0.969	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.031	0.969	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.031	0.969	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.031	0.969	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.031	0.969	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.031	0.969	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.031	0.969	0.000
S36.0 Injury of spleen	0.031	0.969	0.000
S32.41 Fracture of acetabulum (open)	0.030	0.969	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.030	0.969	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.030	0.969	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.030	0.969	0.000
T53.5 Chlorofluorocarbons	0.030	0.969	0.000
T53.4 Dichloromethane	0.030	0.969	0.000
T53.3 Tetrachloroethylene	0.030	0.969	0.000
T53.2 Trichloroethylene	0.030	0.969	0.000
T53.1 Chloroform	0.030	0.969	0.000
T53.0 Carbon tetrachloride	0.030	0.969	0.000
T57.9 Inorganic substance, unspecified	0.030	0.969	0.000
T57.8 Other specified inorganic substances	0.030	0.969	0.000
T57.3 Hydrogen cyanide	0.030	0.969	0.000
T57.2 Manganese and its compounds	0.030	0.969	0.000
T57.1 Phosphorus and its compounds	0.030	0.969	0.000
T57.0 Arsenic and its compounds	0.030	0.969	0.000
T60.9 Pesticide, unspecified	0.030	0.969	0.000
T60.8 Other pesticides	0.030	0.969	0.000
T60.4 Rodenticides	0.030	0.969	0.000
T60.3 Herbicides and fungicides	0.030	0.969	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations