TreeWAS – Variant ID: rs1517352

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.414	0.586
E03 Other hypothyroidism	0.000	0.647	0.353
C18.7 Sigmoid colon	0.000	0.695	0.305
E03.1 Congenital hypothyroidism without goitre	0.000	0.720	0.280
E00-E07 Disorders of thyroid gland	0.000	0.746	0.254
E03.5 Myxoedema coma	0.000	0.747	0.253
E03.4 Atrophy of thyroid (acquired)	0.000	0.747	0.253
E03.3 Postinfectious hypothyroidism	0.000	0.747	0.253
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.753	0.247
E07 Other disorders of thyroid	0.000	0.768	0.232
E07.9 Disorder of thyroid, unspecified	0.000	0.777	0.223
E06 Thyroiditis	0.000	0.778	0.222
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.781	0.219
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.796	0.204
E03.8 Other specified hypothyroidism	0.000	0.810	0.190
E05.9 Thyrotoxicosis, unspecified	0.000	0.812	0.188
E06.3 Autoimmune thyroiditis	0.000	0.814	0.186
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.817	0.182
E00 Congenital iodine-deficiency syndrome	0.000	0.817	0.182
E06.9 Thyroiditis, unspecified	0.000	0.818	0.182
E06.1 Subacute thyroiditis	0.000	0.827	0.173
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.829	0.171
E07.1 Dyshormogenetic goitre	0.000	0.834	0.166
E07.0 Hypersecretion of calcitonin	0.000	0.834	0.166
E06.4 Drug-induced thyroiditis	0.000	0.840	0.159
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.840	0.159
E06.0 Acute thyroiditis	0.000	0.840	0.159
E05.8 Other thyrotoxicosis	0.000	0.851	0.149
E05.5 Thyroid crisis or storm	0.000	0.853	0.147
E05.4 Thyrotoxicosis factitia	0.000	0.853	0.147
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.853	0.147
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.853	0.147
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.855	0.145
E06.5 Other chronic thyroiditis	0.000	0.856	0.144
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.869	0.131
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.869	0.131
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.869	0.131
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.869	0.131
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.869	0.131
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.869	0.131
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.869	0.131
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.869	0.131
E07.8 Other specified disorders of thyroid	0.000	0.877	0.122
E04 Other non-toxic goitre	0.000	0.920	0.080
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.926	0.074
E04.0 Non-toxic diffuse goitre	0.000	0.927	0.073
J34.3 Hypertrophy of nasal turbinates	0.070	0.930	0.000
D86.0 Sarcoidosis of lung	0.068	0.932	0.000
C18 Malignant neoplasm of colon	0.000	0.935	0.065
D86 Sarcoidosis	0.063	0.937	0.000
D86.9 Sarcoidosis, unspecified	0.062	0.938	0.000
C18.3 Hepatic flexure	0.000	0.940	0.060
E04.8 Other specified non-toxic goitre	0.000	0.942	0.058
D86.8 Sarcoidosis of other and combined sites	0.055	0.945	0.000
C18.6 Descending colon	0.000	0.948	0.052
C18.5 Splenic flexure	0.000	0.951	0.049
D86.3 Sarcoidosis of skin	0.049	0.951	0.000
C18.8 Overlapping lesion of colon	0.000	0.951	0.048
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.044	0.955	0.000
C18.1 Appendix	0.000	0.958	0.042
C18.4 Transverse colon	0.000	0.960	0.040
C18.9 Colon, unspecified	0.000	0.963	0.037
E04.1 Non-toxic single thyroid nodule	0.000	0.964	0.036
D86.1 Sarcoidosis of lymph nodes	0.030	0.970	0.000
J34 Other disorders of nose and nasal sinuses	0.025	0.975	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.977	0.023
D80-D89 Certain disorders involving the immune mechanism	0.023	0.977	0.000
J34.2 Deviated nasal septum	0.021	0.979	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.021	0.979	0.000
C18.2 Ascending colon	0.000	0.982	0.018
D80 Immunodeficiency with predominantly antibody defects	0.018	0.982	0.000
D82 Immunodeficiency associated with other major defects	0.017	0.982	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.983	0.017
D81 Combined immunodeficiencies	0.016	0.983	0.000
D84 Other immunodeficiencies	0.016	0.984	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.016	0.984	0.000
E10.2 With renal complications	0.016	0.984	0.000
E10 Insulin-dependent diabetes mellitus	0.016	0.984	0.000
E10.1 With ketoacidosis	0.015	0.984	0.000
E10.5 With peripheral circulatory complications	0.015	0.985	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.015	0.985	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.015	0.985	0.000
E10.4 With neurological complications	0.015	0.985	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.014	0.986	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.986	0.014
D83 Common variable immunodeficiency	0.014	0.986	0.000
D82.1 Di George's syndrome	0.014	0.986	0.000
D84.9 Immunodeficiency, unspecified	0.014	0.986	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.013	0.986	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.013	0.987	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.013	0.987	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.013	0.987	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.013	0.987	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.013	0.987	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.013	0.987	0.000
E10.7 With multiple complications	0.013	0.987	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.013	0.987	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.013	0.987	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.013	0.987	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.013	0.987	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.013	0.987	0.000
D82.2 Immunodeficiency with short-limbed stature	0.013	0.987	0.000
D82.0 Wiskott-Aldrich syndrome	0.013	0.987	0.000
K92.0 Haematemesis	0.012	0.988	0.000
E10.8 With unspecified complications	0.012	0.988	0.000
D81.9 Combined immunodeficiency, unspecified	0.012	0.988	0.000
D81.8 Other combined immunodeficiencies	0.012	0.988	0.000
D81.7 Major histocompatibility complex class II deficiency	0.012	0.988	0.000
D81.6 Major histocompatibility complex class I deficiency	0.012	0.988	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.012	0.988	0.000
D81.4 Nezelof's syndrome	0.012	0.988	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.012	0.988	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.012	0.988	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.012	0.988	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.012	0.988	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.012	0.988	0.000
E10.6 With other specified complications	0.012	0.988	0.000
E10.0 With coma	0.012	0.988	0.000
L03.3 Cellulitis of trunk	0.000	0.988	0.012
C18.0 Caecum	0.000	0.989	0.011
D84.8 Other specified immunodeficiencies	0.011	0.989	0.000
G58.9 Mononeuropathy, unspecified	0.011	0.989	0.000
D84.1 Defects in the complement system	0.010	0.990	0.000
D83.8 Other common variable immunodeficiencies	0.010	0.990	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.010	0.990	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.010	0.990	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.010	0.990	0.000
D89.1 Cryoglobulinaemia	0.010	0.990	0.000
Q05.9 Spina bifida, unspecified	0.010	0.990	0.000
D89.3 Immune reconstitution syndrome	0.010	0.990	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.009	0.990	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.009	0.991	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.009	0.991	0.000
Q05 Spina bifida	0.009	0.991	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.008	0.991	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.992	0.008
G58.8 Other specified mononeuropathies	0.008	0.992	0.000
D83.9 Common variable immunodeficiency, unspecified	0.008	0.992	0.000
G58 Other mononeuropathies	0.008	0.992	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.008	0.992	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.008	0.992	0.000
Q00-Q07 Congenital malformations of the nervous system	0.008	0.992	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.007	0.993	0.000
Z85.6 Personal history of leukaemia	0.007	0.993	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.993	0.007
Q05.4 Unspecified spina bifida with hydrocephalus	0.007	0.993	0.000
Z33 Pregnant state, incidental	0.000	0.993	0.007
Q05.7 Lumbar spina bifida without hydrocephalus	0.006	0.993	0.000
Q53.1 Undescended testicle, unilateral	0.007	0.993	0.000
E10.3 With ophthalmic complications	0.007	0.993	0.000
Q53 Undescended testicle	0.007	0.993	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.006	0.993	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.006	0.993	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.006	0.993	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.006	0.993	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.006	0.993	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.006	0.993	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.006	0.993	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
Q07 Other congenital malformations of nervous system	0.006	0.994	0.000
Q06 Other congenital malformations of spinal cord	0.006	0.994	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.994	0.006
G58.7 Mononeuritis multiplex	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
Q04 Other congenital malformations of brain	0.006	0.994	0.000
Q03 Congenital hydrocephalus	0.006	0.994	0.000
A08.4 Viral intestinal infection, unspecified	0.006	0.994	0.000
Q01 Encephalocele	0.006	0.994	0.000
Q00 Anencephaly and similar malformations	0.006	0.994	0.000
Q02 Microcephaly	0.006	0.994	0.000
S79.9 Unspecified injury of hip and thigh	0.006	0.994	0.000
G58.0 Intercostal neuropathy	0.005	0.994	0.000
Q53.9 Undescended testicle, unspecified	0.005	0.994	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.995	0.005
Q07.0 Arnold-Chiari syndrome	0.005	0.995	0.000
Q53.2 Undescended testicle, bilateral	0.005	0.995	0.000
M35 Other systemic involvement of connective tissue	0.000	0.995	0.005
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
Q06.2 Diastematomyelia	0.005	0.995	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.005	0.995	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.995	0.005
M35.1 Other overlap syndromes	0.000	0.995	0.005
Q53.0 Ectopic testis	0.005	0.995	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.005	0.995	0.000
Q50.3 Other congenital malformations of ovary	0.005	0.995	0.000
Q50.2 Congenital torsion of ovary	0.005	0.995	0.000
Q50.1 Developmental ovarian cyst	0.005	0.995	0.000
Q50.0 Congenital absence of ovary	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
Q07.8 Other specified congenital malformations of nervous system	0.005	0.995	0.000
Q04.6 Congenital cerebral cysts	0.005	0.995	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.005	0.995	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.005	0.995	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.005	0.995	0.000
Q06.4 Hydromyelia	0.005	0.995	0.000
Q06.3 Other congenital cauda equina malformations	0.005	0.995	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.005	0.995	0.000
Q06.0 Amyelia	0.005	0.995	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.995	0.005
Q56 Indeterminate sex and pseudohermaphroditism	0.005	0.995	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.995	0.005
Q03.0 Malformations of aqueduct of Sylvius	0.004	0.995	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.995	0.005
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.995	0.000
Q04.9 Congenital malformation of brain, unspecified	0.004	0.995	0.000
Q04.5 Megalencephaly	0.004	0.995	0.000
Q04.4 Septo-optic dysplasia	0.004	0.995	0.000
Q04.3 Other reduction deformities of brain	0.004	0.995	0.000
Q04.2 Holoprosencephaly	0.004	0.995	0.000
Q04.1 Arhinencephaly	0.004	0.995	0.000
Q04.0 Congenital malformations of corpus callosum	0.004	0.995	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.004	0.996	0.000
Q03.8 Other congenital hydrocephalus	0.004	0.996	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q04.8 Other specified congenital malformations of brain	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
Q00.2 Iniencephaly	0.004	0.996	0.000
Q00.1 Craniorachischisis	0.004	0.996	0.000
Q00.0 Anencephaly	0.004	0.996	0.000
Q01.9 Encephalocele, unspecified	0.004	0.996	0.000
Q01.8 Encephalocele of other sites	0.004	0.996	0.000
Q01.2 Occipital encephalocele	0.004	0.996	0.000
Q01.1 Nasofrontal encephalocele	0.004	0.996	0.000
Q01.0 Frontal encephalocele	0.004	0.996	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.996	0.004
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q40 Other congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
M35.2 Behcet's disease	0.000	0.996	0.004
Q50.5 Embryonic cyst of broad ligament	0.004	0.996	0.000
D13.2 Duodenum	0.004	0.996	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.996	0.004
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.996	0.004
M35.5 Multifocal fibrosclerosis	0.000	0.996	0.004
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.996	0.004
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
Q18.1 Preauricular sinus and cyst	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q17 Other congenital malformations of ear	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.996	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.996	0.000
R30.9 Painful micturition, unspecified	0.004	0.996	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.004	0.996	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.996	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.996	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.996	0.000
Q73 Reduction defects of unspecified limb	0.003	0.996	0.000
Q72 Reduction defects of lower limb	0.003	0.996	0.000
Q71 Reduction defects of upper limb	0.003	0.996	0.000
Q69 Polydactyly	0.003	0.996	0.000
Q10.0 Congenital ptosis	0.003	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.996	0.000
Q30 Congenital malformations of nose	0.003	0.996	0.000
Q37 Cleft palate with cleft lip	0.003	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
D13.4 Liver	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
D13.5 Extrahepatic bile ducts	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
Q17.5 Prominent ear	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.997	0.003
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.997	0.003
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
Q90 Down's syndrome	0.003	0.997	0.000
D13.3 Other and unspecified parts of small intestine	0.003	0.997	0.000
Q10.7 Congenital malformation of orbit	0.003	0.997	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.003	0.997	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.003	0.997	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.003	0.997	0.000
Q10.3 Other congenital malformations of eyelid	0.003	0.997	0.000
Q10.2 Congenital entropion	0.003	0.997	0.000
Q10.1 Congenital ectropion	0.003	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
Q82.0 Hereditary lymphoedema	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
K29.1 Other acute gastritis	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.003	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.003	0.997	0.000
Q17.4 Misplaced ear	0.003	0.997	0.000
Q17.3 Other misshapen ear	0.003	0.997	0.000
Q17.2 Microtia	0.003	0.997	0.000
Q17.1 Macrotia	0.003	0.997	0.000
Q17.0 Accessory auricle	0.003	0.997	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q65.6 Unstable hip	0.003	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
Q30.3 Congenital perforated nasal septum	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q82.2 Mastocytosis	0.003	0.997	0.000
E24 Cushing's syndrome	0.000	0.997	0.003
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
D13.7 Endocrine pancreas	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.997	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q14.3 Congenital malformation of choroid	0.003	0.997	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.997	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.997	0.000
Q30.9 Congenital malformation of nose, unspecified	0.003	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.997	0.000
M89.98 Disorder of bone, unspecified (Other)	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.003	0.997	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q13.5 Blue sclera	0.003	0.997	0.000
Q13.4 Other congenital corneal malformations	0.003	0.997	0.000
Q13.3 Congenital corneal opacity	0.003	0.997	0.000
Q13.2 Other congenital malformations of iris	0.003	0.997	0.000
Q13.1 Absence of iris	0.003	0.997	0.000
Q13.0 Coloboma of iris	0.003	0.997	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.003	0.997	0.000
Q16.5 Congenital malformation of inner ear	0.003	0.997	0.000
Q16.4 Other congenital malformations of middle ear	0.003	0.997	0.000
Q16.3 Congenital malformation of ear ossicles	0.003	0.997	0.000
Q16.2 Absence of eustachian tube	0.003	0.997	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.003	0.997	0.000
Q16.0 Congenital absence of (ear) auricle	0.003	0.997	0.000
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.003	0.997	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.003	0.997	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.003	0.997	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.003	0.997	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.003	0.997	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations