TreeWAS – Variant ID: rs1528580

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
J40-J47 Chronic lower respiratory diseases	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
J44 Other chronic obstructive pulmonary disease	0.999	0.001
# Top node	0.999	0.001
I30-I52 Other forms of heart disease	0.999	0.001
I51 Complications and ill-defined descriptions of heart disease	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.996	0.004
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.996	0.004
J45 Asthma	0.993	0.007
J43 Emphysema	0.987	0.013
Chapter XX External causes of morbidity and mortality	0.987	0.013
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.983	0.017
I51.8 Other ill-defined heart diseases	0.983	0.017
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.981	0.019
I60-I69 Cerebrovascular diseases	0.978	0.022
I71 Aortic aneurysm and dissection	0.975	0.025
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.972	0.028
J90-J94 Other diseases of pleura	0.971	0.029
J45.0 Predominantly allergic asthma	0.970	0.030
J43.9 Emphysema, unspecified	0.970	0.030
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.957	0.043
J90 Pleural effusion, not elsewhere classified	0.953	0.047
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.946	0.054
I51.7 Cardiomegaly	0.945	0.055
S40-S49 Injuries to the shoulder and upper arm	0.938	0.062
Y95 Nosocomial condition	0.934	0.066
J45.9 Asthma, unspecified	0.929	0.071
S60-S69 Injuries to the wrist and hand	0.926	0.074
Chapter V Mental and behavioural disorders	0.919	0.081
J95-J99 Other diseases of the respiratory system	0.919	0.081
I31 Other diseases of pericardium	0.910	0.090
J30-J39 Other diseases of upper respiratory tract	0.909	0.091
I05-I09 Chronic rheumatic heart diseases	0.906	0.094
I45 Other conduction disorders	0.902	0.098
F00-F09 Organic, including symptomatic, mental disorders	0.896	0.104
S10-S19 Injuries to the neck	0.890	0.110
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.880	0.120
J40 Bronchitis, not specified as acute or chronic	0.878	0.122
S49 Other and unspecified injuries of shoulder and upper arm	0.877	0.123
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.874	0.126
Y52 Agents primarily affecting the cardiovascular system	0.873	0.127
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.869	0.131
I74 Arterial embolism and thrombosis	0.868	0.132
J09-J18 Influenza and pneumonia	0.867	0.133
I70 Atherosclerosis	0.865	0.135
I63 Cerebral infarction	0.861	0.139
I69 Sequelae of cerebrovascular disease	0.861	0.139
I60 Subarachnoid haemorrhage	0.860	0.140
I42 Cardiomyopathy	0.855	0.145
S20-S29 Injuries to the thorax	0.854	0.146
T15-T19 Effects of foreign body entering through natural orifice	0.848	0.152
Y41 Other systemic anti-infectives and antiparasitics	0.843	0.157
I71.3 Abdominal aortic aneurysm, ruptured	0.843	0.157
Y44 Agents primarily affecting blood constituents	0.843	0.157
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.841	0.159
Chapter VIII Diseases of the ear and mastoid process	0.841	0.159
I72 Other aneurysm	0.840	0.160
J43.2 Centrilobular emphysema	0.840	0.160
I08 Multiple valve diseases	0.840	0.160
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.839	0.161
I33 Acute and subacute endocarditis	0.839	0.161
S66 Injury of muscle and tendon at wrist and hand level	0.837	0.163
I46 Cardiac arrest	0.835	0.165
S49.9 Unspecified injury of shoulder and upper arm	0.833	0.167
Chapter I Certain infectious and parasitic diseases	0.833	0.167
S60 Superficial injury of wrist and hand	0.831	0.169
J36 Peritonsillar abscess	0.827	0.172
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.827	0.173
Y40 Systemic antibiotics	0.827	0.173
Q20-Q28 Congenital malformations of the circulatory system	0.822	0.178
Y83.2 Surgical operation with anastomosis, bypass or graft	0.822	0.178
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.820	0.180
T79-T79 Certain early complications of trauma	0.820	0.180
I31.3 Pericardial effusion (noninflammatory)	0.817	0.183
J30 Vasomotor and allergic rhinitis	0.816	0.184
T20-T25 Burns and corrosions of external body surface, specified by site	0.815	0.185
H80-H83 Diseases of inner ear	0.813	0.187
I45.1 Other and unspecified right bundle-branch block	0.812	0.188
J35 Chronic diseases of tonsils and adenoids	0.811	0.189
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.809	0.191
J95 Postprocedural respiratory disorders, not elsewhere classified	0.806	0.194
I73 Other peripheral vascular diseases	0.805	0.195
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.804	0.196
S80-S89 Injuries to the knee and lower leg	0.803	0.197
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.802	0.198
B25-B34 Other viral diseases	0.800	0.200
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.799	0.201
F06.7 Mild cognitive disorder	0.799	0.201
J93 Pneumothorax	0.797	0.203
Y48 Anaesthetics and therapeutic gases	0.796	0.204
I51.3 Intracardiac thrombosis, not elsewhere classified	0.796	0.204
Y46 Antiepileptics and anti-Parkinsonism drugs	0.795	0.205
I51.4 Myocarditis, unspecified	0.794	0.206
S20 Superficial injury of thorax	0.793	0.207
I27 Other pulmonary heart diseases	0.792	0.208
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.791	0.209
I70.2 Atherosclerosis of arteries of the extremities	0.789	0.211
S19 Other and unspecified injuries of neck	0.789	0.211
I67 Other cerebrovascular diseases	0.789	0.211
I61 Intracerebral haemorrhage	0.788	0.211
H83 Other diseases of inner ear	0.786	0.213
S69 Other and unspecified injuries of wrist and hand	0.779	0.221
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.778	0.222
I51.9 Heart disease, unspecified	0.773	0.227
J15 Bacterial pneumonia, not elsewhere classified	0.772	0.228
J94 Other pleural conditions	0.771	0.229
H83.0 Labyrinthitis	0.768	0.232
I69.3 Sequelae of cerebral infarction	0.764	0.235
S50-S59 Injuries to the elbow and forearm	0.764	0.236
Q50-Q56 Congenital malformations of genital organs	0.764	0.236
F00 Dementia in Alzheimer's disease	0.763	0.236
T00-T07 Injuries involving multiple body regions	0.762	0.237
S80 Superficial injury of lower leg	0.761	0.239
B34 Viral infection of unspecified site	0.761	0.239
I78 Diseases of capillaries	0.761	0.239
I46.0 Cardiac arrest with successful resuscitation	0.761	0.239
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.759	0.240
T18 Foreign body in alimentary tract	0.758	0.242
J98 Other respiratory disorders	0.757	0.243
W50-W64 Exposure to animate mechanical forces	0.754	0.246
Y52.4 Angiotensin-converting-enzyme inhibitors	0.754	0.246
J44.9 Chronic obstructive pulmonary disease, unspecified	0.753	0.247
J35.1 Hypertrophy of tonsils	0.752	0.248
Y53 Agents primarily affecting the gastro-intestinal system	0.752	0.248
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.751	0.249
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.750	0.250
J10 Influenza due to identified influenza virus	0.749	0.251
I27.9 Pulmonary heart disease, unspecified	0.748	0.252
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.747	0.253
I71.0 Dissection of aorta [any part]	0.747	0.253
F99-F99 Unspecified mental disorder	0.744	0.256
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.742	0.258
I37 Pulmonary valve disorders	0.741	0.259
Q80-Q89 Other congenital malformations	0.740	0.259
Y49 Psychotropic drugs, not elsewhere classified	0.736	0.264
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.736	0.264
I73.9 Peripheral vascular disease, unspecified	0.736	0.264
J14 Pneumonia due to Haemophilus influenzae	0.735	0.265
I31.9 Disease of pericardium, unspecified	0.734	0.266
Y00-Y09 Assault	0.733	0.267
I30 Acute pericarditis	0.732	0.268
S46 Injury of muscle and tendon at shoulder and upper arm level	0.731	0.269
S65 Injury of blood vessels at wrist and hand level	0.730	0.270
Y57 Other and unspecified drugs and medicaments	0.730	0.270
S60.8 Other superficial injuries of wrist and hand	0.729	0.271
S20.2 Contusion of thorax	0.727	0.273
I49 Other cardiac arrhythmias	0.725	0.275
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.725	0.275
I08.1 Disorders of both mitral and tricuspid valves	0.725	0.275
I33.0 Acute and subacute infective endocarditis	0.724	0.276
J39 Other diseases of upper respiratory tract	0.724	0.276
X50-X57 Overexertion, travel and privation	0.722	0.278
X40-X49 Accidental poisoning by and exposure to noxious substances	0.721	0.279
J32 Chronic sinusitis	0.720	0.280
S43.1 Dislocation of acromioclavicular joint	0.719	0.281
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.718	0.282
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284
I48 Atrial fibrillation and flutter	0.716	0.284
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.284
I41 Myocarditis in diseases classified elsewhere	0.716	0.284
I40 Acute myocarditis	0.716	0.284
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284
I32 Pericarditis in diseases classified elsewhere	0.716	0.284
S90-S99 Injuries to the ankle and foot	0.715	0.284
J30.1 Allergic rhinitis due to pollen	0.716	0.284
I51.6 Cardiovascular disease, unspecified	0.715	0.285
I51.5 Myocardial degeneration	0.715	0.285
I51.2 Rupture of papillary muscle, not elsewhere classified	0.715	0.285
Q00-Q07 Congenital malformations of the nervous system	0.714	0.285
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.714	0.286
S68 Traumatic amputation of wrist and hand	0.714	0.286
I42.1 Obstructive hypertrophic cardiomyopathy	0.714	0.286
I69.1 Sequelae of intracerebral haemorrhage	0.712	0.288
J45.8 Mixed asthma	0.712	0.288
J45.1 Nonallergic asthma	0.712	0.288
S41 Open wound of shoulder and upper arm	0.711	0.289
F80-F89 Disorders of psychological development	0.710	0.290
X10-X19 Contact with heat and hot substances	0.708	0.291
S80.9 Superficial injury of lower leg, unspecified	0.708	0.292
I72.3 Aneurysm of iliac artery	0.708	0.292
J43.8 Other emphysema	0.708	0.292
J43.1 Panlobular emphysema	0.708	0.292
J43.0 MacLeod's syndrome	0.708	0.292
Y35-Y36 Legal intervention and operations of war	0.707	0.293
Y10-Y34 Event of undetermined intent	0.707	0.293
X85-X99 Assault	0.707	0.293
X30-X39 Exposure to forces of nature	0.707	0.293
X00-X09 Exposure to smoke, fire and flames	0.707	0.293
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293
W75-W84 Other accidental threats to breathing	0.707	0.293
W65-W74 Accidental drowning and submersion	0.707	0.293
V98-V99 Other and unspecified transport accidents	0.707	0.293
V95-V97 Air and space transport accidents	0.707	0.293
V90-V94 Water transport accidents	0.707	0.293
V70-V79 Bus occupant injured in transport accident	0.707	0.293
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293
V01-V09 Pedestrian injured in transport accident	0.707	0.293
Y91 Evidence of alcohol involvement determined by level of intoxication	0.707	0.293
S43.0 Dislocation of shoulder joint	0.705	0.295
I45.3 Trifascicular block	0.705	0.295
J99 Respiratory disorders in diseases classified elsewhere	0.705	0.295
I05 Rheumatic mitral valve diseases	0.705	0.295
T33-T35 Frostbite	0.705	0.295
T26-T28 Burns and corrosions confined to eye and internal organs	0.705	0.295
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.704	0.296
Y60-Y69 Misadventures to patients during surgical and medical care	0.703	0.297
T79 Certain early complications of trauma, not elsewhere classified	0.703	0.297
I60.9 Subarachnoid haemorrhage, unspecified	0.703	0.297
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.703	0.297
I68 Cerebrovascular disorders in diseases classified elsewhere	0.701	0.299
J95.8 Other postprocedural respiratory disorders	0.701	0.299
Y44.2 Anticoagulants	0.699	0.301
I71.8 Aortic aneurysm of unspecified site, ruptured	0.699	0.301
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.699	0.301
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.699	0.301
I71.1 Thoracic aortic aneurysm, ruptured	0.699	0.301
I74.5 Embolism and thrombosis of iliac artery	0.698	0.302
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.697	0.303
X58-X59 Accidental exposure to other and unspecified factors	0.697	0.303
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.697	0.303
Y59 Other and unspecified vaccines and biological substances	0.696	0.303
Y58 Bacterial vaccines	0.696	0.303
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.696	0.303
Y50 Central nervous system stimulants, not elsewhere classified	0.696	0.303
Y47 Sedatives, hypnotics and antianxiety drugs	0.696	0.303
I45.6 Preexcitation syndrome	0.696	0.304
Y54.3 Benzothiadiazine derivatives	0.696	0.304
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.696	0.304
Y40.1 Cefalosporins and other -lactam antibiotics	0.695	0.305
W20-W49 Exposure to inanimate mechanical forces	0.694	0.306
S19.9 Unspecified injury of neck	0.694	0.306
S27 Injury of other and unspecified intrathoracic organs	0.692	0.308
I42.2 Other hypertrophic cardiomyopathy	0.692	0.308
Y44.5 Thrombolytic drugs	0.689	0.311
I61.8 Other intracerebral haemorrhage	0.689	0.311
X20-X29 Contact with venomous animals and plants	0.689	0.311
J37 Chronic laryngitis and laryngotracheitis	0.688	0.311
J98.1 Pulmonary collapse	0.688	0.312
F03 Unspecified dementia	0.687	0.313
F05 Delirium, not induced by alcohol and other psychoactive substances	0.686	0.314
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.686	0.314
Y98 Lifestyle-related condition	0.686	0.314
Y97 Environmental-pollution-related condition	0.686	0.314
Y96 Work-related condition	0.686	0.314
Y83.3 Surgical operation with formation of external stoma	0.686	0.314
F01 Vascular dementia	0.683	0.317
I51.0 Cardiac septal defect, acquired	0.681	0.318
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.680	0.319
J93.9 Pneumothorax, unspecified	0.681	0.319
B15-B19 Viral hepatitis	0.680	0.320
I74.9 Embolism and thrombosis of unspecified artery	0.680	0.320
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.680	0.320
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.678	0.322
Q35-Q37 Cleft lip and cleft palate	0.678	0.322
Q30-Q34 Congenital malformations of the respiratory system	0.678	0.322
B35-B49 Mycoses	0.678	0.322
B34.9 Viral infection, unspecified	0.678	0.322
Q21 Congenital malformations of cardiac septa	0.678	0.322
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.678	0.322
S69.9 Unspecified injury of wrist and hand	0.674	0.326
Y52.1 Calcium-channel blockers	0.674	0.326
S48 Traumatic amputation of shoulder and upper arm	0.672	0.328
S45 Injury of blood vessels at shoulder and upper arm level	0.672	0.328
S44 Injury of nerves at shoulder and upper arm level	0.672	0.328
S47 Crushing injury of shoulder and upper arm	0.672	0.328
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.672	0.328
V40-V49 Car occupant injured in transport accident	0.671	0.328
J00-J06 Acute upper respiratory infections	0.671	0.329
Y48.3 Local anaesthetics	0.671	0.329
V20-V29 Motorcycle rider injured in transport accident	0.671	0.329
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.670	0.330
Q38-Q45 Other congenital malformations of the digestive system	0.669	0.331
Y46.2 Hydantoin derivatives	0.668	0.332
I67.2 Cerebral atherosclerosis	0.668	0.332
Q25 Congenital malformations of great arteries	0.667	0.333
S60.2 Contusion of other parts of wrist and hand	0.666	0.334
I72.8 Aneurysm of other specified arteries	0.664	0.335
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.664	0.336
I42.9 Cardiomyopathy, unspecified	0.664	0.336
S67 Crushing injury of wrist and hand	0.663	0.337
T18.1 Foreign body in oesophagus	0.663	0.337
I08.0 Disorders of both mitral and aortic valves	0.662	0.338
S10 Superficial injury of neck	0.662	0.338
I45.8 Other specified conduction disorders	0.660	0.340
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.659	0.341
F70-F79 Mental retardation	0.659	0.341
J96 Respiratory failure, not elsewhere classified	0.659	0.341
B34.8 Other viral infections of unspecified site	0.659	0.341
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.659	0.341
V80-V89 Other land transport accidents	0.658	0.342
I69.0 Sequelae of subarachnoid haemorrhage	0.658	0.342
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.655	0.345
Q66 Congenital deformities of feet	0.655	0.345
S66.8 Injury of other muscles and tendons at wrist and hand level	0.653	0.347
I31.8 Other specified diseases of pericardium	0.652	0.347
I31.2 Haemopericardium, not elsewhere classified	0.652	0.347
I31.1 Chronic constrictive pericarditis	0.652	0.347
I31.0 Chronic adhesive pericarditis	0.652	0.347
Y40.0 Penicillins	0.653	0.347
I45.9 Conduction disorder, unspecified	0.652	0.348
Q65 Congenital deformities of hip	0.651	0.349
I64 Stroke, not specified as haemorrhage or infarction	0.651	0.349
I09 Other rheumatic heart diseases	0.650	0.350
I06 Rheumatic aortic valve diseases	0.650	0.350
S13.4 Sprain and strain of cervical spine	0.650	0.350
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.649	0.351
F30-F39 Mood [affective] disorders	0.648	0.352
J30.3 Other allergic rhinitis	0.647	0.353
I45.4 Nonspecific intraventricular block	0.647	0.353
I45.0 Right fascicular block	0.647	0.353
I34 Nonrheumatic mitral valve disorders	0.645	0.355
X60-X84 Intentional self-harm	0.645	0.355
I67.9 Cerebrovascular disease, unspecified	0.644	0.356
F02 Dementia in other diseases classified elsewhere	0.643	0.357
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.642	0.358
F09 Unspecified organic or symptomatic mental disorder	0.642	0.358
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.642	0.358
F00.9 Dementia in Alzheimer's disease, unspecified	0.642	0.358
Q24 Other congenital malformations of heart	0.641	0.359
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.641	0.359
B50-B64 Protozoal diseases	0.639	0.361
S17 Crushing injury of neck	0.638	0.362
S15 Injury of blood vessels at neck level	0.638	0.362
S14 Injury of nerves and spinal cord at neck level	0.638	0.362
S11 Open wound of neck	0.638	0.362
S18 Traumatic amputation at neck level	0.638	0.362
S16 Injury of muscle and tendon at neck level	0.638	0.362
Chapter VI Diseases of the nervous system	0.637	0.363
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.637	0.363
I67.1 Cerebral aneurysm, nonruptured	0.634	0.365
H80 Otosclerosis	0.634	0.366
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.632	0.368
J95.0 Tracheostomy malfunction	0.630	0.370
S20.8 Superficial injuries of other and unspecified parts of thorax	0.629	0.371
I36 Nonrheumatic tricuspid valve disorders	0.629	0.371
S49.8 Other specified injuries of shoulder and upper arm	0.629	0.371
S49.7 Multiple injuries of shoulder and upper arm	0.629	0.371
B27 Infectious mononucleosis	0.628	0.372
B95-B98 Bacterial, viral and other infectious agents	0.628	0.372
S80.8 Other superficial injuries of lower leg	0.627	0.373
J32.4 Chronic pansinusitis	0.627	0.373
I28 Other diseases of pulmonary vessels	0.626	0.374
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.626	0.374
Y52.8 Antivaricose drugs, including sclerosing agents	0.626	0.374
Y52.7 Peripheral vasodilators	0.626	0.374
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.626	0.374
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.626	0.374
Y40.9 Systemic antibiotic, unspecified	0.626	0.374
S50 Superficial injury of forearm	0.625	0.375
I72.0 Aneurysm of carotid artery	0.625	0.375
Y52.3 Coronary vasodilators, not elsewhere classified	0.624	0.375
T23 Burn and corrosion of wrist and hand	0.624	0.376
T21 Burn and corrosion of trunk	0.623	0.377
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.622	0.377
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.622	0.378
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.622	0.378
I74.0 Embolism and thrombosis of abdominal aorta	0.622	0.378
J17 Pneumonia in diseases classified elsewhere	0.622	0.378
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.622	0.378
J12 Viral pneumonia, not elsewhere classified	0.622	0.378
J09 Influenza due to certain identified influenza virus	0.622	0.378
B25 Cytomegaloviral disease	0.621	0.379
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.621	0.379
I70.9 Generalised and unspecified atherosclerosis	0.620	0.380
I70.8 Atherosclerosis of other arteries	0.620	0.380
I70.1 Atherosclerosis of renal artery	0.620	0.380
S19.8 Other specified injuries of neck	0.620	0.380
I74.8 Embolism and thrombosis of other arteries	0.620	0.380
I49.0 Ventricular fibrillation and flutter	0.619	0.381
S86 Injury of muscle and tendon at lower leg level	0.619	0.381
Chapter XXII Codes for special purposes	0.618	0.382
F99 Mental disorder, not otherwise specified	0.618	0.382
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.617	0.382
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.617	0.382
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.617	0.382
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.617	0.383
J15.2 Pneumonia due to staphylococcus	0.617	0.383
I60.8 Other subarachnoid haemorrhage	0.617	0.383
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.617	0.383
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.617	0.383
I60.5 Subarachnoid haemorrhage from vertebral artery	0.617	0.383
I60.4 Subarachnoid haemorrhage from basilar artery	0.617	0.383
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.617	0.383
J15.0 Pneumonia due to Klebsiella pneumoniae	0.616	0.384
I45.5 Other specified heart block	0.615	0.385
S80.1 Contusion of other and unspecified parts of lower leg	0.614	0.386
J46 Status asthmaticus	0.614	0.386
S56 Injury of muscle and tendon at forearm level	0.614	0.386
J35.2 Hypertrophy of adenoids	0.613	0.386
I42.8 Other cardiomyopathies	0.613	0.387
I42.7 Cardiomyopathy due to drugs and other external agents	0.613	0.387
I42.6 Alcoholic cardiomyopathy	0.613	0.387
I42.5 Other restrictive cardiomyopathy	0.613	0.387
I42.4 Endocardial fibroelastosis	0.613	0.387
I42.3 Endomyocardial (eosinophilic) disease	0.613	0.387
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.612	0.388
S26 Injury of heart	0.612	0.388
S25 Injury of blood vessels of thorax	0.612	0.388
S24 Injury of nerves and spinal cord at thorax level	0.612	0.388
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.612	0.388
S21 Open wound of thorax	0.612	0.388
T18.0 Foreign body in mouth	0.612	0.388
F29 Unspecified nonorganic psychosis	0.610	0.390
J94.1 Fibrothorax	0.610	0.390
I73.8 Other specified peripheral vascular diseases	0.609	0.391
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.608	0.392
T19 Foreign body in genito-urinary tract	0.608	0.392
T15 Foreign body on external eye	0.608	0.392
T16 Foreign body in ear	0.608	0.392
A80-A89 Viral infections of the central nervous system	0.608	0.392
B34.4 Papovirus infection, unspecified	0.607	0.393
S89 Other and unspecified injuries of lower leg	0.606	0.393
J15.1 Pneumonia due to Pseudomonas	0.606	0.394
S60.9 Superficial injury of wrist and hand, unspecified	0.606	0.394
S54 Injury of nerves at forearm level	0.606	0.394
J30.4 Allergic rhinitis, unspecified	0.605	0.395
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.605	0.395
Y41.5 Antiviral drugs	0.605	0.395
Y41.4 Anthelminthics	0.605	0.395
Y41.3 Other antiprotozoal drugs	0.605	0.395
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.605	0.395
Y41.1 Antimycobacterial drugs	0.605	0.395
Y41.0 Sulphonamides	0.605	0.395
T79.7 Traumatic subcutaneous emphysema	0.604	0.396
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.604	0.396
T00 Superficial injuries involving multiple body regions	0.604	0.396
Y44.9 Other and unspecified agents affecting blood constituents	0.604	0.396
Y44.7 Plasma substitutes	0.604	0.396
Y44.6 Natural blood and blood products	0.604	0.396
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.604	0.396
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.604	0.396
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.604	0.396
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.604	0.396
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.603	0.397
S43.6 Sprain and strain of sternoclavicular joint	0.603	0.397
S43.5 Sprain and strain of acromioclavicular joint	0.603	0.397
S43.4 Sprain and strain of shoulder joint	0.603	0.397
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.603	0.397
S43.2 Dislocation of sternoclavicular joint	0.603	0.397
Y51 Drugs primarily affecting the autonomic nervous system	0.603	0.397
I72.9 Aneurysm of unspecified site	0.602	0.398
I72.6 Aneurysm and dissection of vertebral artery	0.602	0.398
I72.5 Aneurysm and dissection of other precerebral arteries	0.602	0.398
I72.2 Aneurysm of renal artery	0.602	0.398
I72.1 Aneurysm of artery of upper extremity	0.602	0.398
I08.9 Multiple valve disease, unspecified	0.602	0.398
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.602	0.398
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.602	0.398
F06.6 Organic emotionally labile [asthenic] disorder	0.602	0.398
F06.5 Organic dissociative disorder	0.602	0.398
F06.4 Organic anxiety disorder	0.602	0.398
F06.3 Organic mood [affective] disorders	0.602	0.398
F06.2 Organic delusional [schizophrenia-like] disorder	0.602	0.398
F06.1 Organic catatonic disorder	0.602	0.398
F06.0 Organic hallucinosis	0.602	0.398
I33.9 Acute endocarditis, unspecified	0.601	0.399
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.600	0.400
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.600	0.400
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.600	0.400
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.600	0.400
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.600	0.400
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.600	0.400
I26 Pulmonary embolism	0.600	0.400
Q27 Other congenital malformations of peripheral vascular system	0.600	0.400
J94.2 Haemothorax	0.599	0.401
S62 Fracture at wrist and hand level	0.599	0.401
I46.1 Sudden cardiac death, so described	0.598	0.401
B85-B89 Pediculosis, acariasis and other infestations	0.597	0.402
B65-B83 Helminthiases	0.597	0.402
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.597	0.402
A75-A79 Rickettsioses	0.597	0.402
A70-A74 Other diseases caused by chlamydiae	0.597	0.402
A65-A69 Other spirochaetal diseases	0.597	0.402
A20-A28 Certain zoonotic bacterial diseases	0.597	0.402
A15-A19 Tuberculosis	0.597	0.402
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.596	0.403
I45.2 Bifascicular block	0.596	0.404
I63.8 Other cerebral infarction	0.596	0.404
S60.7 Multiple superficial injuries of wrist and hand	0.596	0.404
S60.1 Contusion of finger(s) with damage to nail	0.596	0.404
S60.0 Contusion of finger(s) without damage to nail	0.596	0.404
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.595	0.405
F00.0 Dementia in Alzheimer's disease with early onset	0.595	0.405
J93.0 Spontaneous tension pneumothorax	0.594	0.406
Y53.1 Other antacids and anti-gastric-secretion drugs	0.594	0.406
Y40.7 Antifungal antibiotics, systemically used	0.593	0.407
Y40.6 Rifamycins	0.593	0.407
Y40.5 Aminoglycosides	0.593	0.407
Y40.4 Tetracyclines	0.593	0.407
Y40.3 Macrolides	0.593	0.407
Y40.2 Chloramphenicol group	0.593	0.407
F60-F69 Disorders of adult personality and behaviour	0.591	0.408
H81 Disorders of vestibular function	0.591	0.409
S20.3 Other superficial injuries of front wall of thorax	0.591	0.409

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations