TreeWAS – Variant ID: rs1533106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G40.9 Epilepsy, unspecified	0.000	0.627	0.373
G40 Epilepsy	0.000	0.651	0.349
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.671	0.329
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.680	0.320
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.681	0.319
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.744	0.256
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.751	0.249
G40.8 Other epilepsy	0.000	0.758	0.242
G40.5 Special epileptic syndromes	0.000	0.784	0.216
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.785	0.214
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.791	0.209
R45.8 Other symptoms and signs involving emotional state	0.000	0.980	0.020
N85.4 Malposition of uterus	0.013	0.987	0.000
R45 Symptoms and signs involving emotional state	0.000	0.989	0.011
G40-G47 Episodic and paroxysmal disorders	0.000	0.989	0.011
R45.1 Restlessness and agitation	0.000	0.990	0.010
O32.1 Maternal care for breech presentation	0.010	0.990	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.010	0.990	0.000
O03.9 Complete or unspecified, without complication	0.000	0.990	0.010
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.991	0.009
D86.0 Sarcoidosis of lung	0.009	0.991	0.000
R45.0 Nervousness	0.000	0.991	0.009
R45.4 Irritability and anger	0.000	0.991	0.008
G41 Status epilepticus	0.000	0.991	0.009
R45.2 Unhappiness	0.000	0.992	0.008
R45.3 Demoralisation and apathy	0.000	0.992	0.008
G44 Other headache syndromes	0.000	0.992	0.008
R45.5 Hostility	0.000	0.992	0.008
D86.1 Sarcoidosis of lymph nodes	0.008	0.992	0.000
G41.2 Complex partial status epilepticus	0.000	0.992	0.008
Z82.3 Family history of stroke	0.000	0.992	0.008
D86 Sarcoidosis	0.007	0.993	0.000
R45.6 Physical violence	0.000	0.993	0.007
G44.3 Chronic posttraumatic headache	0.000	0.993	0.007
R45.7 State of emotional shock and stress, unspecified	0.000	0.993	0.007
G41.9 Status epilepticus, unspecified	0.000	0.993	0.007
G44.0 Cluster headache syndrome	0.000	0.993	0.007
K43 Ventral hernia	0.000	0.993	0.007
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.994	0.006
G41.1 Petit mal status epilepticus	0.000	0.994	0.006
D86.8 Sarcoidosis of other and combined sites	0.006	0.994	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.994	0.006
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.994	0.006
G41.8 Other status epilepticus	0.000	0.994	0.005
S63.6 Sprain and strain of finger(s)	0.000	0.994	0.006
G44.1 Vascular headache, not elsewhere classified	0.000	0.994	0.005
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
D86.3 Sarcoidosis of skin	0.005	0.995	0.000
G41.0 Grand mal status epilepticus	0.000	0.995	0.005
Z87.8 Personal history of other specified conditions	0.000	0.995	0.005
G43 Migraine	0.000	0.995	0.005
N36.2 Urethral caruncle	0.005	0.995	0.000
K43.1 Ventral hernia with gangrene	0.000	0.995	0.005
G44.8 Other specified headache syndromes	0.000	0.995	0.005
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.995	0.005
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.995	0.005
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.995	0.005
K43.4 Parastomal hernia with gangrene	0.000	0.995	0.005
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.995	0.005
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.995	0.005
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
Y83.8 Other surgical procedures	0.000	0.995	0.005
G46.2 Posterior cerebral artery syndrome	0.000	0.995	0.004
Q89.2 Congenital malformations of other endocrine glands	0.000	0.995	0.005
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.995	0.004
G46.6 Pure sensory lacunar syndrome	0.000	0.995	0.004
G46.5 Pure motor lacunar syndrome	0.000	0.995	0.004
G46.1 Anterior cerebral artery syndrome	0.000	0.995	0.004
G46.0 Middle cerebral artery syndrome	0.000	0.995	0.004
G43.3 Complicated migraine	0.000	0.996	0.004
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.996	0.004
G44.2 Tension-type headache	0.000	0.996	0.004
N92.6 Irregular menstruation, unspecified	0.000	0.996	0.004
G43.8 Other migraine	0.000	0.996	0.004
O03 Spontaneous abortion	0.000	0.996	0.004
G43.2 Status migrainosus	0.000	0.996	0.004
N87.9 Dysplasia of cervix uteri, unspecified	0.004	0.996	0.000
G46.4 Cerebellar stroke syndrome	0.000	0.996	0.004
N36 Other disorders of urethra	0.004	0.996	0.000
G46.7 Other lacunar syndromes	0.000	0.996	0.004
G43.0 Migraine without aura [common migraine]	0.000	0.996	0.004
G46.3 Brain stem stroke syndrome	0.000	0.996	0.003
O26.9 Pregnancy-related condition, unspecified	0.004	0.996	0.000
N36.8 Other specified disorders of urethra	0.004	0.996	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.996	0.004
N36.9 Urethral disorder, unspecified	0.004	0.996	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.996	0.004
Z03.8 Observation for other suspected diseases and conditions	0.004	0.996	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.996	0.004
K26.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.996	0.004
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.996	0.004
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.996	0.003
N36.3 Prolapsed urethral mucosa	0.003	0.996	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.997	0.003
Z90.0 Acquired absence of part of head and neck	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.997	0.003
K22.5 Diverticulum of oesophagus, acquired	0.000	0.997	0.003
N36.1 Urethral diverticulum	0.003	0.997	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.997	0.003
O03.7 Complete or unspecified, complicated by embolism	0.000	0.997	0.003
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.997	0.003
O03.2 Incomplete, complicated by embolism	0.000	0.997	0.003
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.997	0.003
G43.9 Migraine, unspecified	0.000	0.997	0.003
Z82.2 Family history of deafness and hearing loss	0.000	0.997	0.003
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.000	0.997	0.003
O03.3 Incomplete, with other and unspecified complications	0.000	0.997	0.003
R52.9 Pain, unspecified	0.000	0.997	0.003
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.997	0.003
F05.9 Delirium, unspecified	0.000	0.997	0.003
S63.5 Sprain and strain of wrist	0.000	0.997	0.003
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
G45.0 Vertebro-basilar artery syndrome	0.000	0.997	0.003
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.003	0.997	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.003	0.997	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.997	0.003
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.997	0.003
O32.9 Maternal care for malpresentation of foetus, unspecified	0.003	0.997	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.997	0.003
Q82.5 Congenital nonneoplastic naevus	0.000	0.997	0.003
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.997	0.003
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.997	0.003
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.997	0.003
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.997	0.003
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.997	0.003
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.997	0.003
Y40.0 Penicillins	0.003	0.997	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.997	0.003
O32.6 Maternal care for compound presentation	0.003	0.997	0.000
Z82.1 Family history of blindness and visual loss	0.000	0.997	0.002
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.997	0.003
Q89.9 Congenital malformation, unspecified	0.000	0.997	0.002
Q89.8 Other specified congenital malformations	0.000	0.997	0.002
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.997	0.002
Q89.4 Conjoined twins	0.000	0.997	0.002
Q89.1 Congenital malformations of adrenal gland	0.000	0.997	0.002
Q89.0 Congenital malformations of spleen	0.000	0.997	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.997	0.002
S00.0 Superficial injury of scalp	0.000	0.997	0.003
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.997	0.003
G43.1 Migraine with aura [classical migraine]	0.000	0.997	0.002
O32.0 Maternal care for unstable lie	0.002	0.997	0.000
Q89.3 Situs inversus	0.000	0.997	0.002
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
R77.8 Other specified abnormalities of plasma proteins	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
K60.0 Acute anal fissure	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
D16.3 Short bones of lower limb	0.000	0.998	0.002
R77 Other abnormalities of plasma proteins	0.002	0.998	0.000
S63.0 Dislocation of wrist	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.998	0.002
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.000	0.998	0.002
R76 Other abnormal immunological findings in serum	0.002	0.998	0.000
R76.0 Raised antibody titer	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
R77.1 Abnormality of globulin	0.002	0.998	0.000
S63.1 Dislocation finger	0.000	0.998	0.002
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.998	0.002
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
G45.3 Amaurosis fugax	0.000	0.998	0.002
R78.0 Finding of alcohol in blood	0.002	0.998	0.000
S63.2 Multiple dislocations of fingers	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
N87.0 Mild cervical dysplasia	0.002	0.998	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
R78 Findings of drugs and other substances, not normally found in blood	0.002	0.998	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
R77.9 Abnormality of plasma protein, unspecified	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.998	0.002
N87 Dysplasia of cervix uteri	0.002	0.998	0.000
R71 Abnormality of red blood cells	0.002	0.998	0.000
R77.2 Abnormality of alphafetoprotein	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.998	0.002
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.998	0.002
K61.0 Anal abscess	0.000	0.998	0.002
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.000	0.998	0.002
Q82.4 Ectodermal dysplasia (anhidrotic)	0.000	0.998	0.002
Q82.3 Incontinentia pigmenti	0.000	0.998	0.002
Q82.1 Xeroderma pigmentosum	0.000	0.998	0.002
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.998	0.002
R76.2 False-positive serological test for syphilis	0.002	0.998	0.000
R76.1 Abnormal reaction to tuberculin test	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
N36.0 Urethral fistula	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.000	0.998	0.002
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.998	0.002
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
Q82.2 Mastocytosis	0.000	0.998	0.002
W55.0 Home	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.998	0.002
Q84 Other congenital malformations of integument	0.000	0.998	0.002
Q81 Epidermolysis bullosa	0.000	0.998	0.002
M06.32 Rheumatoid nodule (Upper arm)	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.998	0.002
I22 Subsequent myocardial infarction	0.002	0.998	0.000
O32.4 Maternal care for high head at term	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.998	0.002
Q83.1 Accessory breast	0.000	0.998	0.002
R70.1 Abnormal plasma viscosity	0.002	0.998	0.000
R77.0 Abnormality of albumin	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.998	0.002
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.998	0.002
R78.9 Finding of unspecified substance, not normally found in blood	0.002	0.998	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.002	0.998	0.000
R78.6 Finding of steroid agent in blood	0.002	0.998	0.000
R78.5 Finding of psychotropic drug in blood	0.002	0.998	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.002	0.998	0.000
R78.3 Finding of hallucinogen in blood	0.002	0.998	0.000
R78.2 Finding of cocaine in blood	0.002	0.998	0.000
R78.1 Finding of opiate drug in blood	0.002	0.998	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.002	0.998	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
Q80 Congenital ichthyosis	0.000	0.998	0.002
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
R78.8 Finding of other specified substances, not normally found in blood	0.002	0.998	0.000
W13.9 Unspecified place	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.000	0.998	0.002
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.002
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.998	0.001
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.998	0.002
Q85.9 Phakomatosis, unspecified	0.000	0.998	0.001
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.998	0.001
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.000	0.998	0.001
Q83.2 Absent nipple	0.000	0.998	0.001
Q83.0 Congenital absence of breast with absent nipple	0.000	0.998	0.001
S12.1 Fracture of second cervical vertebra	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.000	0.998	0.001
Q81.8 Other epidermolysis bullosa	0.000	0.998	0.001
Q81.2 Epidermolysis bullosa dystrophica	0.000	0.998	0.001
Q81.1 Epidermolysis bullosa letalis	0.000	0.998	0.001
Q81.0 Epidermolysis bullosa simplex	0.000	0.998	0.001
Q84.9 Congenital malformation of integument, unspecified	0.000	0.998	0.001
Q84.8 Other specified congenital malformations of integument	0.000	0.998	0.001
Q84.6 Other congenital malformations of nails	0.000	0.998	0.001
Q84.5 Enlarged and hypertrophic nails	0.000	0.998	0.001
Q84.4 Congenital leukonychia	0.000	0.998	0.001
Q84.3 Anonychia	0.000	0.998	0.001
Q84.2 Other congenital malformations of hair	0.000	0.998	0.001
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.000	0.998	0.001
Q84.0 Congenital alopecia	0.000	0.998	0.001
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.000	0.998	0.001
Q86.2 Dysmorphism due to warfarin	0.000	0.998	0.001
Q86.1 Foetal hydantoin syndrome	0.000	0.998	0.001
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.000	0.998	0.001
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.001	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.998	0.002
Q83.3 Accessory nipple	0.000	0.998	0.001
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.001	0.998	0.000
K09.2 Other cysts of jaw	0.000	0.998	0.002
M05.0 Felty's syndrome	0.001	0.998	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.001	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.001	0.998	0.000
M06.38 Rheumatoid nodule (Other)	0.001	0.998	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.001	0.998	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.001	0.998	0.000
Q80.8 Other congenital ichthyosis	0.000	0.998	0.001
Q80.4 Harlequin foetus	0.000	0.998	0.001
Q80.3 Congenital bullous ichthyosiform erythroderma	0.000	0.998	0.001
Q80.2 Lamellar ichthyosis	0.000	0.998	0.001
Q80.1 X-linked ichthyosis	0.000	0.998	0.001
Q80.0 Ichthyosis vulgaris	0.000	0.998	0.001
D81 Combined immunodeficiencies	0.001	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.998	0.001
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
M05.8 Other seropositive rheumatoid arthritis	0.001	0.998	0.000
M05.09 Felty's syndrome (Site unspecified)	0.001	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.001	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.002	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
M79.69 Pain in limb (Site unspecified)	0.002	0.998	0.000
D16.0 Scapula and long bones of upper limb	0.000	0.998	0.001
D73.8 Other diseases of spleen	0.000	0.998	0.001
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.001	0.999	0.000
D73.5 Infarction of spleen	0.000	0.999	0.001
Q80.9 Congenital ichthyosis, unspecified	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
T92.4 Sequelae of injury of nerve of upper limb	0.001	0.999	0.000
D16.4 Bones of skull and face	0.000	0.999	0.001
Q85.1 Tuberous sclerosis	0.000	0.999	0.001
M05.18 Rheumatoid lung disease (Other)	0.001	0.999	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.001	0.999	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.001	0.999	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.001	0.999	0.000
M05.14 Rheumatoid lung disease (Hand)	0.001	0.999	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.001	0.999	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.001	0.999	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.001	0.999	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.000	0.999	0.001
C21.0 Anus, unspecified	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.999	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.001	0.999	0.000
K81.9 Cholecystitis, unspecified	0.000	0.999	0.001
Q83.8 Other congenital malformations of breast	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
N61 Inflammatory disorders of breast	0.001	0.999	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
F05.8 Other delirium	0.000	0.999	0.001
F12.1 Harmful use	0.000	0.999	0.001
O26.0 Excessive weight gain in pregnancy	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.000	0.999	0.001
D16 Benign neoplasm of bone and articular cartilage	0.000	0.999	0.001
D84 Other immunodeficiencies	0.001	0.999	0.000
M05.08 Felty's syndrome (Other)	0.001	0.999	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.001	0.999	0.000
M05.06 Felty's syndrome (Lower leg)	0.001	0.999	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.001	0.999	0.000
M05.04 Felty's syndrome (Hand)	0.001	0.999	0.000
M05.03 Felty's syndrome (Forearm)	0.001	0.999	0.000
M05.02 Felty's syndrome (Upper arm)	0.001	0.999	0.000
M05.01 Felty's syndrome (Shoulder region)	0.001	0.999	0.000
M05.00 Felty's syndrome (Multiple sites)	0.001	0.999	0.000
O26.5 Maternal hypotension syndrome	0.001	0.999	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
D16.2 Long bones of lower limb	0.000	0.999	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
J39.2 Other diseases of pharynx	0.001	0.999	0.000
M05.2 Rheumatoid vasculitis	0.001	0.999	0.000
N70.1 Chronic salpingitis and oophoritis	0.001	0.999	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.001	0.999	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.001	0.999	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.001	0.999	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.999	0.000
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999	0.000
K63.3 Ulcer of intestine	0.000	0.999	0.001
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.999	0.001
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.001	0.999	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.001	0.999	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.001	0.999	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.001	0.999	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.001	0.999	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.001	0.999	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.001	0.999	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.001	0.999	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.001	0.999	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
G37.5 Concentric sclerosis [Balo]	0.001	0.999	0.000
G37.4 Subacute necrotising myelitis	0.001	0.999	0.000
G37.2 Central pontine myelinolysis	0.001	0.999	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.999	0.000
G37.0 Diffuse sclerosis	0.001	0.999	0.000
S00.7 Multiple superficial injuries of head	0.000	0.999	0.001
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.999	0.001
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
I12.9 Hypertensive renal disease without renal failure	0.001	0.999	0.000
M06.9 Rheumatoid arthritis, unspecified	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.000	0.999	0.001
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.001	0.999	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.001	0.999	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.000	0.999	0.001
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.999	0.001
D16.7 Ribs, sternum and clavicle	0.000	0.999	0.001
D73.4 Cyst of spleen	0.000	0.999	0.001
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
Q64 Other congenital malformations of urinary system	0.000	0.999	0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
E80.4 Gilbert's syndrome	0.000	0.999	0.001
H61.8 Other specified disorders of external ear	0.001	0.999	0.000
I44.1 Atrioventricular block, second degree	0.000	0.999	0.001
I68.0 Cerebral amyloid angiopathy	0.000	0.999	0.001
K22.0 Achalasia of cardia	0.000	0.999	0.001
U89.8 Agent resistant to other single specified antibiotic	0.000	0.999	0.001
O26 Maternal care for other conditions predominantly related to pregnancy	0.001	0.999	0.000
M05.28 Rheumatoid vasculitis (Other)	0.001	0.999	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.999	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.999	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.999	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.999	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.999	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.999	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.999	0.001
D16.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
D36.7 Other specified sites	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.999	0.001
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
D16.1 Short bones of upper limb	0.000	0.999	0.001
M94.8 Other specified disorders of cartilage	0.000	0.999	0.001
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.000	0.999	0.001
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.999	0.000
C32.1 Supraglottis	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.001	0.999	0.000
Q64.4 Malformation of urachus	0.000	0.999	0.001
S12 Fracture of neck	0.000	0.999	0.001
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
D16.6 Vertebral column	0.000	0.999	0.001
Q63.2 Ectopic kidney	0.000	0.999	0.001
H31.8 Other specified disorders of choroid	0.000	0.999	0.001
K09.9 Cyst of oral region, unspecified	0.000	0.999	0.001
N03.9 Unspecified	0.001	0.999	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.999	0.001
Q64.8 Other specified congenital malformations of urinary system	0.000	0.999	0.001
Q64.6 Congenital diverticulum of bladder	0.000	0.999	0.001
Q64.5 Congenital absence of bladder and urethra	0.000	0.999	0.001
Q64.2 Congenital posterior urethral valves	0.000	0.999	0.001
Q64.1 Exstrophy of urinary bladder	0.000	0.999	0.001
Q64.0 Epispadias	0.000	0.999	0.001
S00.9 Superficial injury of head, part unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations