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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1543796
log Bayes Factor = 54.0095
Chromosome 6   position 28,990,618  (GRCh37) Explore rs1543796 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.035 0.965
E10.2 With renal complications
0.000 0.052 0.948
E10.4 With neurological complications
0.000 0.131 0.869
E10.1 With ketoacidosis
0.000 0.174 0.826
E16.1 Other hypoglycaemia
0.000 0.182 0.818
E05.8 Other thyrotoxicosis
0.000 0.197 0.803
E13 Other specified diabetes mellitus
0.000 0.211 0.789
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.216 0.784
E10.7 With multiple complications
0.000 0.246 0.754
E40-E46 Malnutrition
0.000 0.258 0.742
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.715
E16.3 Increased secretion of glucagon
0.000 0.284 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.289 0.711
E10.6 With other specified complications
0.000 0.312 0.688
E14 Unspecified diabetes mellitus
0.000 0.320 0.680
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.358 0.642
E10.5 With peripheral circulatory complications
0.000 0.361 0.639
E06 Thyroiditis
0.000 0.364 0.636
E13.9 Without complications
0.000 0.368 0.632
E07 Other disorders of thyroid
0.000 0.387 0.613
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.587
E03 Other hypothyroidism
0.000 0.421 0.579
E14.3 With ophthalmic complications
0.000 0.423 0.577
E13.3 With ophthalmic complications
0.000 0.424 0.576
E13.8 With unspecified complications
0.000 0.434 0.566
E13.7 With multiple complications
0.000 0.434 0.566
E13.6 With other specified complications
0.000 0.434 0.566
E13.5 With peripheral circulatory complications
0.000 0.434 0.566
E13.4 With neurological complications
0.000 0.434 0.566
E13.2 With renal complications
0.000 0.434 0.566
E13.1 With ketoacidosis
0.000 0.434 0.566
E13.0 With coma
0.000 0.434 0.566
E46 Unspecified protein-energy malnutrition
0.000 0.442 0.558
E14.1 With ketoacidosis
0.000 0.462 0.538
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.468 0.532
E45 Retarded development following protein-energy malnutrition
0.000 0.468 0.532
E43 Unspecified severe protein-energy malnutrition
0.000 0.468 0.532
E42 Marasmic kwashiorkor
0.000 0.468 0.532
E41 Nutritional marasmus
0.000 0.468 0.532
E40 Kwashiorkor
0.000 0.468 0.532
E06.9 Thyroiditis, unspecified
0.000 0.471 0.529
E10.8 With unspecified complications
0.000 0.471 0.528
E14.6 With other specified complications
0.000 0.476 0.524
E14.8 With unspecified complications
0.000 0.481 0.519
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512
E14.4 With neurological complications
0.000 0.503 0.497
E14.7 With multiple complications
0.000 0.513 0.487
E07.8 Other specified disorders of thyroid
0.000 0.515 0.485
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.484 0.516 0.000
E06.1 Subacute thyroiditis
0.000 0.519 0.481
E14.5 With peripheral circulatory complications
0.000 0.533 0.467
K90 Intestinal malabsorption
0.000 0.535 0.465
E14.0 With coma
0.000 0.541 0.459
E06.4 Drug-induced thyroiditis
0.000 0.544 0.456
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.544 0.456
E06.0 Acute thyroiditis
0.000 0.544 0.456
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.545 0.454
E14.2 Withrenal complications
0.000 0.549 0.451
E06.5 Other chronic thyroiditis
0.000 0.558 0.442
E07.1 Dyshormogenetic goitre
0.000 0.560 0.440
E07.0 Hypersecretion of calcitonin
0.000 0.560 0.440
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.564 0.436
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.574 0.426
E03.5 Myxoedema coma
0.000 0.585 0.415
E03.4 Atrophy of thyroid (acquired)
0.000 0.585 0.415
E03.3 Postinfectious hypothyroidism
0.000 0.585 0.415
E03.1 Congenital hypothyroidism without goitre
0.000 0.596 0.404
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.609 0.391
E44.1 Mild protein-energy malnutrition
0.000 0.618 0.381
E44.0 Moderate protein-energy malnutrition
0.000 0.618 0.381
E65-E68 Obesity and other hyperalimentation
0.000 0.620 0.380
E03.8 Other specified hypothyroidism
0.000 0.640 0.360
E50-E64 Other nutritional deficiencies
0.000 0.646 0.354
K90.3 Pancreatic steatorrhoea
0.000 0.666 0.333
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.666 0.333
K90.1 Tropical sprue
0.000 0.666 0.333
K90.8 Other intestinal malabsorption
0.000 0.675 0.325
E03.9 Hypothyroidism, unspecified
0.000 0.680 0.320
E67 Other hyperalimentation
0.000 0.727 0.273
E68 Sequelae of hyperalimentation
0.000 0.727 0.273
K90.9 Intestinal malabsorption, unspecified
0.000 0.729 0.271
E11 Non-insulin-dependent diabetes mellitus
0.000 0.738 0.262
E51 Thiamine deficiency
0.000 0.746 0.254
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.746 0.254
E50 Vitamin A deficiency
0.000 0.746 0.254
E60 Dietary zinc deficiency
0.000 0.746 0.254
E59 Dietary selenium deficiency
0.000 0.746 0.254
E52 Niacin deficiency [pellagra]
0.000 0.746 0.254
E54 Ascorbic acid deficiency
0.000 0.751 0.249
E65 Localised adiposity
0.000 0.755 0.245
E56 Other vitamin deficiencies
0.000 0.759 0.241
E55 Vitamin D deficiency
0.000 0.759 0.241
E11.6 With other specified complications
0.000 0.759 0.241
E07.9 Disorder of thyroid, unspecified
0.000 0.759 0.241
E20-E35 Disorders of other endocrine glands
0.000 0.761 0.239
E58 Dietary calcium deficiency
0.000 0.766 0.234
E63 Other nutritional deficiencies
0.000 0.770 0.230
R31 Unspecified haematuria
0.225 0.775 0.000
E24 Cushing's syndrome
0.000 0.779 0.221
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.784 0.216
E11.1 With ketoacidosis
0.000 0.786 0.214
E61 Deficiency of other nutrient elements
0.000 0.787 0.213
E21.3 Hyperparathyroidism, unspecified
0.000 0.792 0.208
E11.0 With coma
0.000 0.799 0.201
E11.2 With renal complications
0.000 0.800 0.200
M45.X9 Ankylosing spondylitis (Site unspecified)
0.199 0.801 0.000
E67.8 Other specified hyperalimentation
0.000 0.804 0.196
E67.3 Hypervitaminosis D
0.000 0.804 0.196
E67.2 Megavitamin-B6 syndrome
0.000 0.804 0.196
E67.1 Hypercarotenaemia
0.000 0.804 0.196
E67.0 Hypervitaminosis A
0.000 0.804 0.196
E24.9 Cushing's syndrome, unspecified
0.000 0.808 0.192
E11.7 With multiple complications
0.000 0.812 0.188
E53 Deficiency of other B group vitamins
0.000 0.813 0.187
E24.0 Pituitary-dependent Cushing's disease
0.000 0.814 0.186
E51.2 Wernicke's encephalopathy
0.000 0.817 0.183
E51.9 Thiamine deficiency, unspecified
0.000 0.817 0.182
E51.8 Other manifestations of thiamine deficiency
0.000 0.817 0.182
E51.1 Beriberi
0.000 0.817 0.182
E50.9 Vitamin A deficiency, unspecified
0.000 0.818 0.182
E50.8 Other manifestations of vitamin A deficiency
0.000 0.818 0.182
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.818 0.182
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.818 0.182
E50.5 Vitamin A deficiency with night blindness
0.000 0.818 0.182
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.818 0.182
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.818 0.182
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.818 0.182
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.818 0.182
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.818 0.182
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.818 0.182
E64.8 Sequelae of other nutritional deficiencies
0.000 0.818 0.182
E64.3 Sequelae of rickets
0.000 0.818 0.182
E64.2 Sequelae of vitamin C deficiency
0.000 0.818 0.182
E64.1 Sequelae of vitamin A deficiency
0.000 0.818 0.182
E64.0 Sequelae of protein-energy malnutrition
0.000 0.818 0.182
E24.2 Drug-induced Cushing's syndrome
0.000 0.825 0.175
E20 Hypoparathyroidism
0.000 0.826 0.173
E56.9 Vitamin deficiency, unspecified
0.000 0.827 0.173
E56.8 Deficiency of other vitamins
0.000 0.827 0.173
E56.0 Deficiency of vitamin E
0.000 0.827 0.173
E55.0 Rickets, active
0.000 0.827 0.173
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.828 0.171
E32 Diseases of thymus
0.000 0.828 0.171
E30 Disorders of puberty, not elsewhere classified
0.000 0.828 0.171
E06.3 Autoimmune thyroiditis
0.000 0.829 0.171
E21.4 Other specified disorders of parathyroid gland
0.000 0.831 0.169
E25 Adrenogenital disorders
0.000 0.833 0.167
E63.8 Other specified nutritional deficiencies
0.000 0.835 0.165
E63.1 Imbalance of constituents of food intake
0.000 0.835 0.165
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.835 0.165
E31 Polyglandular dysfunction
0.000 0.836 0.164
E56.1 Deficiency of vitamin K
0.000 0.839 0.160
E55.9 Vitamin D deficiency, unspecified
0.000 0.840 0.160
E24.8 Other Cushing's syndrome
0.000 0.841 0.159
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.841 0.159
E24.3 Ectopic ACTH syndrome
0.000 0.841 0.159
E24.1 Nelson's syndrome
0.000 0.841 0.159
E28 Ovarian dysfunction
0.000 0.843 0.157
E21.2 Other hyperparathyroidism
0.000 0.843 0.157
E11.8 With unspecified complications
0.000 0.845 0.155
E61.9 Deficiency of nutrient element, unspecified
0.000 0.847 0.153
E61.8 Deficiency of other specified nutrient elements
0.000 0.847 0.153
E61.7 Deficiency of multiple nutrient elements
0.000 0.847 0.153
E61.6 Vanadium deficiency
0.000 0.847 0.153
E61.5 Molybdenum deficiency
0.000 0.847 0.153
E61.4 Chromium deficiency
0.000 0.847 0.153
E61.3 Manganese deficiency
0.000 0.847 0.153
E61.0 Copper deficiency
0.000 0.847 0.153
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.849 0.151
E53.9 Vitamin B deficiency, unspecified
0.000 0.854 0.145
E29 Testicular dysfunction
0.000 0.856 0.144
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.858 0.142
E63.9 Nutritional deficiency, unspecified
0.000 0.858 0.141
E61.1 Iron deficiency
0.000 0.861 0.139
E53.1 Pyridoxine deficiency
0.000 0.866 0.134
E53.0 Riboflavin deficiency
0.000 0.866 0.134
E34 Other endocrine disorders
0.000 0.868 0.132
E61.2 Magnesium deficiency
0.000 0.869 0.131
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.872 0.128
E20.9 Hypoparathyroidism, unspecified
0.000 0.873 0.127
E20.8 Other hypoparathyroidism
0.000 0.875 0.124
E20.1 Pseudohypoparathyroidism
0.000 0.875 0.124
E20.0 Idiopathic hypoparathyroidism
0.000 0.875 0.124
E30.9 Disorder of puberty, unspecified
0.000 0.877 0.123
E30.8 Other disorders of puberty
0.000 0.877 0.123
E30.1 Precocious puberty
0.000 0.877 0.123
E30.0 Delayed puberty
0.000 0.877 0.123
E32.9 Disease of thymus, unspecified
0.000 0.877 0.123
E32.8 Other diseases of thymus
0.000 0.877 0.123
E32.1 Abscess of thymus
0.000 0.877 0.123
E32.0 Persistent hyperplasia of thymus
0.000 0.877 0.123
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.877 0.123
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.877 0.123
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.877 0.123
E25.9 Adrenogenital disorder, unspecified
0.000 0.880 0.120
E25.8 Other adrenogenital disorders
0.000 0.880 0.120
E31.9 Polyglandular dysfunction, unspecified
0.000 0.882 0.118
E31.8 Other polyglandular dysfunction
0.000 0.882 0.118
E31.1 Polyglandular hyperfunction
0.000 0.882 0.118
E83 Disorders of mineral metabolism
0.111 0.883 0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.884 0.115
E28.2 Polycystic ovarian syndrome
0.000 0.886 0.114
E26 Hyperaldosteronism
0.000 0.886 0.113
E11.3 With ophthalmic complications
0.000 0.887 0.113
E28.9 Ovarian dysfunction, unspecified
0.000 0.887 0.113
E28.8 Other ovarian dysfunction
0.000 0.887 0.113
E28.1 Androgen excess
0.000 0.887 0.113
E28.0 Oestrogen excess
0.000 0.887 0.113
E21.0 Primary hyperparathyroidism
0.000 0.887 0.113
E31.0 Autoimmune polyglandular failure
0.000 0.889 0.111
E29.9 Testicular dysfunction, unspecified
0.000 0.894 0.106
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.896 0.104
E29.8 Other testicular dysfunction
0.000 0.896 0.103
E29.0 Testicular hyperfunction
0.000 0.896 0.103
E11.5 With peripheral circulatory complications
0.000 0.898 0.102
E22 Hyperfunction of pituitary gland
0.000 0.899 0.101
E34.3 Short stature, not elsewhere classified
0.000 0.903 0.097
E28.3 Primary ovarian failure
0.000 0.904 0.096
M45 Ankylosing spondylitis
0.095 0.905 0.000
C15-C26 Malignant neoplasms of digestive organs
0.000 0.905 0.095
E34.5 Androgen resistance syndrome
0.000 0.905 0.095
E34.4 Constitutional tall stature
0.000 0.905 0.095
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.905 0.095
E34.1 Other hypersecretion of intestinal hormones
0.000 0.905 0.095
C20 Malignant neoplasm of rectum
0.000 0.905 0.095
C15 Malignant neoplasm of oesophagus
0.000 0.906 0.094
S02.4 Fracture of malar and maxillary bones
0.000 0.909 0.091
E83.3 Disorders of phosphorus metabolism
0.089 0.910 0.002
E34.9 Endocrine disorder, unspecified
0.000 0.912 0.087
C15.5 Lower third of oesophagus
0.000 0.913 0.087
I83 Varicose veins of lower extremities
0.086 0.914 0.000
E83.8 Other disorders of mineral metabolism
0.080 0.916 0.005
E83.2 Disorders of zinc metabolism
0.080 0.916 0.005
E83.0 Disorders of copper metabolism
0.080 0.916 0.005
E14.9 Without complications
0.000 0.916 0.084
E34.8 Other specified endocrine disorders
0.000 0.917 0.083
E83.9 Disorder of mineral metabolism, unspecified
0.079 0.917 0.004
S02 Fracture of skull and facial bones
0.000 0.918 0.082
E26.8 Other hyperaldosteronism
0.000 0.918 0.081
E26.1 Secondary hyperaldosteronism
0.000 0.918 0.081
E34.0 Carcinoid syndrome
0.000 0.918 0.081
C15.4 Middle third of oesophagus
0.000 0.918 0.082
C25 Malignant neoplasm of pancreas
0.000 0.919 0.081
C15.9 Oesophagus, unspecified
0.000 0.922 0.078
M45.X2 Ankylosing spondylitis (Cervical region)
0.076 0.924 0.000
C15.0 Cervical part of oesophagus
0.000 0.927 0.073
S02.0 Fracture of vault of skull
0.000 0.927 0.073
M45.X6 Ankylosing spondylitis (Lumbar region)
0.073 0.927 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.927 0.072
E22.8 Other hyperfunction of pituitary gland
0.000 0.928 0.072
E29.1 Testicular hypofunction
0.000 0.928 0.072
S02.8 Fractures of other skull and facial bones
0.000 0.928 0.072
E22.1 Hyperprolactinaemia
0.000 0.929 0.071
C17 Malignant neoplasm of small intestine
0.000 0.929 0.071
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.930 0.070
S02.3 Fracture of orbital floor
0.000 0.931 0.069
C25.1 Body of pancreas
0.000 0.931 0.069
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.069 0.931 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.069 0.931 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.069 0.931 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.069 0.931 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.069 0.931 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.069 0.931 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.932 0.068
C25.3 Pancreatic duct
0.000 0.932 0.068
E23 Hypofunction and other disorders of pituitary gland
0.000 0.932 0.068
C15.8 Overlapping lesion of oesophagus
0.000 0.932 0.068
C15.2 Abdominal part of oesophagus
0.000 0.932 0.068
C17.0 Duodenum
0.000 0.933 0.067
S02.00 Fracture of vault of skull (closed)
0.000 0.933 0.067
C25.2 Tail of pancreas
0.000 0.933 0.066
C15.1 Thoracic part of oesophagus
0.000 0.934 0.066
Z71.8 Other specified counselling
0.066 0.934 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.935 0.065
S02.6 Fracture of mandible
0.000 0.935 0.065
C15.3 Upper third of oesophagus
0.000 0.935 0.064
S02.7 Multiple fractures involving skull and facial bones
0.000 0.936 0.064
S02.5 Fracture of tooth
0.000 0.936 0.064
C25.4 Endocrine pancreas
0.000 0.937 0.063
C24.0 Extrahepatic bile duct
0.000 0.937 0.063
C25.8 Overlapping lesion of pancreas
0.000 0.939 0.061
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.939 0.061
S02.30 Fracture of orbital floor (closed)
0.000 0.940 0.060
I83.0 Varicose veins of lower extremities with ulcer
0.059 0.941 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.943 0.057
S02.2 Fracture of nasal bones
0.000 0.944 0.056
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.056 0.944 0.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.945 0.055
C25.7 Other parts of pancreas
0.000 0.946 0.053
E23.7 Disorder of pituitary gland, unspecified
0.000 0.946 0.053
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.053 0.947 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.947 0.053
C25.9 Pancreas, unspecified
0.000 0.947 0.053
S02.60 Fracture of mandible (closed)
0.000 0.947 0.053
S02.01 Fracture of vault of skull (open)
0.000 0.947 0.053
S02.81 Fractures of other skull and facial bones (open)
0.000 0.948 0.052
C17.8 Overlapping lesion of small intestine
0.000 0.949 0.051
C17.3 Meckel's diverticulum
0.000 0.949 0.051
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.949 0.051
E22.0 Acromegaly and pituitary gigantism
0.000 0.949 0.051
C24.8 Overlapping lesion of biliary tract
0.000 0.950 0.050
E11.4 With neurological complications
0.000 0.950 0.050
S02.50 Fracture of tooth (closed)
0.000 0.950 0.050
S02.31 Fracture of orbital floor (open)
0.000 0.950 0.050
C17.1 Jejunum
0.000 0.951 0.049
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.951 0.049
E23.1 Drug-induced hypopituitarism
0.000 0.951 0.049
C24.9 Biliary tract, unspecified
0.000 0.951 0.049
S02.1 Fracture of base of skull
0.000 0.952 0.048
S02.61 Fracture of mandible (open)
0.000 0.953 0.047
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.953 0.046
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.954 0.046
S02.51 Fracture of tooth (open)
0.000 0.954 0.046
E04 Other non-toxic goitre
0.005 0.955 0.041
S02.21 Fracture of nasal bones (open)
0.000 0.955 0.045
C23 Malignant neoplasm of gallbladder
0.000 0.955 0.044
E26.0 Primary hyperaldosteronism
0.001 0.956 0.043
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.956 0.044
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.959 0.041
C21.2 Cloacogenic zone
0.000 0.960 0.040
E11.9 Without complications
0.000 0.961 0.039
E27 Other disorders of adrenal gland
0.000 0.962 0.038
C17.9 Small intestine, unspecified
0.000 0.962 0.038
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.962 0.038
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.962 0.038
E83.4 Disorders of magnesium metabolism
0.034 0.963 0.003
E53.8 Deficiency of other specified B group vitamins
0.000 0.964 0.036
E23.6 Other disorders of pituitary gland
0.000 0.966 0.034
C17.2 Ileum
0.000 0.966 0.034
C26.8 Overlapping lesion of digestive system
0.000 0.966 0.033
C26.1 Spleen
0.000 0.966 0.033
S02.11 Fracture of base of skull (open)
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.003 0.967 0.029
C21.0 Anus, unspecified
0.000 0.967 0.032
E70-E90 Metabolic disorders
0.002 0.968 0.030
C21.1 Anal canal
0.000 0.970 0.030
E23.2 Diabetes insipidus
0.000 0.971 0.029
E66 Obesity
0.000 0.971 0.029
S02.20 Fracture of nasal bones (closed)
0.000 0.971 0.029
K90-K93 Other diseases of the digestive system
0.000 0.971 0.029
C22.9 Liver, unspecified
0.000 0.972 0.028
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.972 0.028
E27.5 Adrenomedullary hyperfunction
0.000 0.972 0.028
E27.0 Other adrenocortical overactivity
0.000 0.972 0.028
E27.1 Primary adrenocortical insufficiency
0.000 0.972 0.028
C22.7 Other specified carcinomas of liver
0.000 0.972 0.027
C22.4 Other sarcomas of liver
0.000 0.972 0.027
C22.3 Angiosarcoma of liver
0.000 0.972 0.027
C22.2 Hepatoblastoma
0.000 0.972 0.027
E78.2 Mixed hyperlipidaemia
0.000 0.972 0.028
C25.0 Head of pancreas
0.000 0.973 0.027
C24.1 Ampulla of Vater
0.001 0.974 0.026
C26.0 Intestinal tract, part unspecified
0.000 0.974 0.026
E78.5 Hyperlipidaemia, unspecified
0.000 0.974 0.026
C26.9 Ill-defined sites within the digestive system
0.000 0.975 0.024
E27.9 Disorder of adrenal gland, unspecified
0.000 0.975 0.024
E73 Lactose intolerance
0.001 0.975 0.024
S02.10 Fracture of base of skull (closed)
0.000 0.976 0.024
E74 Other disorders of carbohydrate metabolism
0.001 0.976 0.023
E78.1 Pure hyperglyceridaemia
0.000 0.976 0.024
E04.0 Non-toxic diffuse goitre
0.004 0.977 0.019
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.977 0.022
E77 Disorders of glycoprotein metabolism
0.001 0.977 0.022
E76 Disorders of glycosaminoglycan metabolism
0.001 0.977 0.022
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.977 0.022
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.977 0.022
C18 Malignant neoplasm of colon
0.000 0.977 0.023
C18.9 Colon, unspecified
0.000 0.977 0.023
E27.2 Addisonian crisis
0.000 0.977 0.022
E78.6 Lipoprotein deficiency
0.000 0.978 0.022
E70 Disorders of aromatic amino-acid metabolism
0.001 0.978 0.021
E78.3 Hyperchylomicronaemia
0.000 0.978 0.021
E23.0 Hypopituitarism
0.000 0.978 0.021
E85 Amyloidosis
0.001 0.979 0.020
I83.1 Varicose veins of lower extremities with inflammation
0.021 0.979 0.000
C18.1 Appendix
0.000 0.979 0.021
E66.1 Drug-induced obesity
0.000 0.979 0.021
E72 Other disorders of amino-acid metabolism
0.001 0.979 0.020
E88 Other metabolic disorders
0.001 0.979 0.021
E79 Disorders of purine and pyrimidine metabolism
0.001 0.979 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.021
C22.1 Intrahepatic bile duct carcinoma
0.000 0.979 0.021
S00-S09 Injuries to the head
0.000 0.979 0.021
E84 Cystic fibrosis
0.001 0.980 0.019
E73.9 Lactose intolerance, unspecified
0.000 0.980 0.019
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.980 0.019
S05 Injury of eye and orbit
0.000 0.981 0.019
C16 Malignant neoplasm of stomach
0.000 0.981 0.019
I77 Other disorders of arteries and arterioles
0.000 0.981 0.019
E27.8 Other specified disorders of adrenal gland
0.000 0.982 0.018
E78.4 Other hyperlipidaemia
0.000 0.982 0.018
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.982 0.018
I77.6 Arteritis, unspecified
0.000 0.982 0.018
E73.8 Other lactose intolerance
0.001 0.982 0.017
E73.1 Secondary lactase deficiency
0.001 0.982 0.017
E73.0 Congenital lactase deficiency
0.001 0.982 0.017
E88.9 Metabolic disorder, unspecified
0.000 0.982 0.017
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.982 0.018
E75.5 Other lipid storage disorders
0.001 0.983 0.017
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.983 0.017
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.983 0.017
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.983 0.017
E74.2 Disorders of galactose metabolism
0.001 0.983 0.017
E74.1 Disorders of fructose metabolism
0.001 0.983 0.017
E74.0 Glycogen storage disease
0.001 0.983 0.017
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.983 0.017
C18.8 Overlapping lesion of colon
0.000 0.983 0.017
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.983 0.017
I77.8 Other specified disorders of arteries and arterioles
0.000 0.983 0.017
E66.0 Obesity due to excess calories
0.000 0.983 0.017
E75.6 Lipid storage disorder, unspecified
0.001 0.983 0.016
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.983 0.016
E75.3 Sphingolipidosis, unspecified
0.001 0.983 0.016
E75.1 Other gangliosidosis
0.001 0.983 0.016
E75.0 GM2 gangliosidosis
0.001 0.983 0.016
E85.4 Organ-limited amyloidosis
0.001 0.983 0.016
E71.3 Disorders of fatty-acid metabolism
0.001 0.983 0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.983 0.016
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.983 0.016
E71.0 Maple-syrup-urine disease
0.001 0.983 0.016
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.983 0.016
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.983 0.016
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.983 0.016
E76.2 Other mucopolysaccharidoses
0.001 0.983 0.016
E76.1 Mucopolysaccharidosis, type II
0.001 0.983 0.016
E76.0 Mucopolysaccharidosis, type I
0.001 0.983 0.016
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.983 0.016
E77.8 Other disorders of glycoprotein metabolism
0.001 0.983 0.016
E77.1 Defects in glycoprotein degradation
0.001 0.983 0.016
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.983 0.016
S00 Superficial injury of head
0.000 0.983 0.017
E75.2 Other sphingolipidosis
0.001 0.983 0.016
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.983 0.016
I77.1 Stricture of artery
0.000 0.984 0.016
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.984 0.016
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.984 0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.984 0.015
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.984 0.015
E70.2 Disorders of tyrosine metabolism
0.001 0.984 0.015
E70.1 Other hyperphenylalaninaemias
0.001 0.984 0.015
E70.0 Classical phenylketonuria
0.001 0.984 0.015
E88.2 Lipomatosis, not elsewhere classified
0.000 0.984 0.015
E85.3 Secondary systemic amyloidosis
0.001 0.984 0.015
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.984 0.015
S05.8 Other injuries of eye and orbit
0.000 0.984 0.016
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.984 0.016
E85.8 Other amyloidosis
0.001 0.984 0.015
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.984 0.015
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.984 0.015
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.984 0.015
S00.0 Superficial injury of scalp
0.000 0.984 0.016
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.985 0.014
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.985 0.014
E72.5 Disorders of glycine metabolism
0.001 0.985 0.014
E72.4 Disorders of ornithine metabolism
0.001 0.985 0.014
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.985 0.014
E72.2 Disorders of urea cycle metabolism
0.001 0.985 0.014
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.985 0.014
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.985 0.014
E79.1 Lesch-Nyhan syndrome
0.001 0.985 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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