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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs154988
log Bayes Factor = 122.937
Chromosome 6   position 32,877,266  (GRCh37) Explore rs154988 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
E10.2 With renal complications
0.000 0.012 0.988
E14.3 With ophthalmic complications
0.000 0.014 0.986
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.015 0.985
E10.8 With unspecified complications
0.000 0.017 0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.021 0.979
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
E11 Non-insulin-dependent diabetes mellitus
0.000 0.031 0.969
H36.0 Diabetic retinopathy
0.000 0.035 0.965
E10.0 With coma
0.000 0.036 0.964
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.067 0.933
M06 Other rheumatoid arthritis
0.000 0.075 0.925
J33.0 Polyp of nasal cavity
0.000 0.078 0.922
E06 Thyroiditis
0.000 0.084 0.916
J33 Nasal polyp
0.000 0.095 0.905
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.098 0.902
M05-M14 Inflammatory polyarthropathies
0.000 0.099 0.901
M05 Seropositive rheumatoid arthritis
0.000 0.099 0.901
E14.9 Without complications
0.000 0.100 0.900
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.100 0.900
J33.9 Nasal polyp, unspecified
0.000 0.102 0.898
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.105 0.895
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.111 0.889
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.122 0.878
E11.2 With renal complications
0.000 0.140 0.860
E11.1 With ketoacidosis
0.000 0.153 0.847
M35 Other systemic involvement of connective tissue
0.000 0.153 0.847
E10.6 With other specified complications
0.000 0.154 0.846
E11.9 Without complications
0.000 0.182 0.818
E14.8 With unspecified complications
0.000 0.183 0.816
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.184 0.816
E11.3 With ophthalmic complications
0.000 0.187 0.813
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.192 0.808
E06.3 Autoimmune thyroiditis
0.000 0.201 0.799
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.202 0.798
E14.6 With other specified complications
0.000 0.202 0.798
E14.1 With ketoacidosis
0.000 0.206 0.794
E11.5 With peripheral circulatory complications
0.000 0.207 0.793
M20-M25 Other joint disorders
0.000 0.214 0.786
E11.6 With other specified complications
0.000 0.222 0.778
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.226 0.774
J33.8 Other polyp of sinus
0.000 0.227 0.773
M06.4 Inflammatory polyarthropathy
0.000 0.234 0.766
M86-M90 Other osteopathies
0.000 0.246 0.754
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.250 0.750
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.254 0.746
M86 Osteomyelitis
0.000 0.257 0.743
L40.9 Psoriasis, unspecified
0.741 0.259 0.000
M34 Systemic sclerosis
0.000 0.260 0.740
E06.9 Thyroiditis, unspecified
0.000 0.264 0.736
M86.9 Osteomyelitis, unspecified
0.000 0.264 0.736
M32 Systemic lupus erythematosus
0.000 0.279 0.721
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.716
E06.5 Other chronic thyroiditis
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.709 0.291 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.299 0.701
M05.8 Other seropositive rheumatoid arthritis
0.000 0.299 0.701
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.300 0.700
E03.1 Congenital hypothyroidism without goitre
0.000 0.302 0.698
E13 Other specified diabetes mellitus
0.000 0.303 0.697
E11.7 With multiple complications
0.000 0.305 0.694
J45 Asthma
0.000 0.306 0.694
M35.7 Hypermobility syndrome
0.000 0.313 0.687
E40-E46 Malnutrition
0.000 0.318 0.682
J33.1 Polypoid sinus degeneration
0.000 0.322 0.677
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.324 0.676
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.324 0.676
E06.1 Subacute thyroiditis
0.000 0.329 0.671
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.333 0.667
E03.8 Other specified hypothyroidism
0.000 0.334 0.666
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.334 0.666
K90 Intestinal malabsorption
0.000 0.335 0.665
E14.2 Withrenal complications
0.000 0.337 0.663
M06.2 Rheumatoid bursitis
0.000 0.337 0.663
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.339 0.660
M35.0 Sicca syndrome [Sjogren]
0.000 0.340 0.660
M34.1 CR(E)ST syndrome
0.000 0.341 0.659
E06.4 Drug-induced thyroiditis
0.000 0.343 0.657
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.343 0.657
E06.0 Acute thyroiditis
0.000 0.343 0.657
M90 Osteopathies in diseases classified elsewhere
0.000 0.348 0.652
E14.4 With neurological complications
0.000 0.352 0.648
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.353 0.647
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.354 0.646
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.354 0.646
M05.1 Rheumatoid lung disease
0.000 0.354 0.646
M05.0 Felty's syndrome
0.000 0.354 0.646
E11.8 With unspecified complications
0.000 0.355 0.645
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.358 0.642
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.361 0.639
M08 Juvenile arthritis
0.000 0.372 0.628
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.376 0.624
M12 Other specific arthropathies
0.000 0.377 0.623
M21 Other acquired deformities of limbs
0.000 0.378 0.622
M22 Disorders of patella
0.000 0.380 0.620
M31 Other necrotising vasculopathies
0.000 0.380 0.620
M06.1 Adult-onset Still's disease
0.000 0.380 0.620
E05.8 Other thyrotoxicosis
0.000 0.386 0.614
E50-E64 Other nutritional deficiencies
0.000 0.386 0.613
M91-M94 Chondropathies
0.000 0.386 0.614
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.393 0.607
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.393 0.607
M35.5 Multifocal fibrosclerosis
0.000 0.393 0.607
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.393 0.607
M34.8 Other forms of systemic sclerosis
0.000 0.393 0.607
M90.7 Fracture of bone in neoplastic disease
0.000 0.396 0.604
M75 Shoulder lesions
0.000 0.397 0.603
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.399 0.601
M70-M79 Other soft tissue disorders
0.000 0.400 0.600
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.599 0.401 0.000
L40 Psoriasis
0.597 0.403 0.000
M75.3 Calcific tendinitis of shoulder
0.000 0.405 0.595
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.406 0.594
J40-J47 Chronic lower respiratory diseases
0.000 0.412 0.588
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.414 0.586
J44 Other chronic obstructive pulmonary disease
0.000 0.415 0.585
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.417 0.583
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.419 0.581
M34.0 Progressive systemic sclerosis
0.000 0.420 0.580
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.421 0.579
M06.8 Other specified rheumatoid arthritis
0.000 0.422 0.578
L40.5 Arthropathic psoriasis
0.572 0.428 0.000
M86.8 Other osteomyelitis
0.000 0.431 0.569
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.432 0.568
M86.6 Other chronic osteomyelitis
0.000 0.432 0.568
K90.9 Intestinal malabsorption, unspecified
0.000 0.433 0.567
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.435 0.565
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.437 0.563
M34.9 Systemic sclerosis, unspecified
0.000 0.438 0.562
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.438 0.562
J43 Emphysema
0.000 0.438 0.562
E07 Other disorders of thyroid
0.000 0.438 0.562
M14 Arthropathies in other diseases classified elsewhere
0.000 0.439 0.560
M21.4 Flat foot [pes planus] (acquired)
0.000 0.440 0.560
C82.0 Small cleaved cell, follicular
0.554 0.446 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.447 0.553
J43.9 Emphysema, unspecified
0.000 0.448 0.552
M05.2 Rheumatoid vasculitis
0.000 0.448 0.551
M75.0 Adhesive capsulitis of shoulder
0.000 0.448 0.552
M75.9 Shoulder lesion, unspecified
0.000 0.449 0.551
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.450 0.549
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.450 0.549
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.450 0.549
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.450 0.549
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.450 0.549
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.450 0.549
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.450 0.549
M60-M63 Disorders of muscles
0.000 0.451 0.549
M32.8 Other forms of systemic lupus erythematosus
0.000 0.453 0.547
M06.3 Rheumatoid nodule
0.000 0.458 0.542
M21.0 Valgus deformity, not elsewhere classified
0.000 0.458 0.542
M90.78 Fracture of bone in neoplastic disease (Other)
0.000 0.460 0.540
E61 Deficiency of other nutrient elements
0.000 0.463 0.537
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.467 0.533
M86.3 Chronic multifocal osteomyelitis
0.000 0.467 0.533
M86.2 Subacute osteomyelitis
0.000 0.467 0.533
M86.0 Acute haematogenous osteomyelitis
0.000 0.467 0.533
M75.2 Bicipital tendinitis
0.000 0.469 0.531
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.469 0.530
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.472 0.527
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.472 0.527
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.472 0.527
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.472 0.527
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.474 0.526
M35.1 Other overlap syndromes
0.000 0.474 0.525
M86.1 Other acute osteomyelitis
0.000 0.475 0.525
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.476 0.524
M11 Other crystal arthropathies
0.000 0.477 0.523
M21.1 Varus deformity, not elsewhere classified
0.000 0.477 0.523
M10 Gout
0.000 0.481 0.519
M22.0 Recurrent dislocation of patella
0.000 0.482 0.518
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.483 0.517
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.483 0.517
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.484 0.516
E16.1 Other hypoglycaemia
0.000 0.484 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13.9 Without complications
0.000 0.489 0.510
M88 Paget's disease of bone [osteitis deformans]
0.000 0.490 0.510
E11.4 With neurological complications
0.000 0.491 0.509
M22.9 Disorder of patella, unspecified
0.000 0.491 0.509
C82.3 Follicular lymphoma grade IIIa
0.508 0.492 0.000
E11.0 With coma
0.000 0.492 0.508
M75.4 Impingement syndrome of shoulder
0.000 0.495 0.505
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.497 0.502
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.497 0.502
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.497 0.502
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.497 0.502
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.497 0.502
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.497 0.502
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.497 0.502
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.497 0.502
E13.8 With unspecified complications
0.000 0.500 0.499
E13.7 With multiple complications
0.000 0.500 0.499
E13.6 With other specified complications
0.000 0.500 0.499
E13.5 With peripheral circulatory complications
0.000 0.500 0.499
E13.4 With neurological complications
0.000 0.500 0.499
E13.2 With renal complications
0.000 0.500 0.499
E13.1 With ketoacidosis
0.000 0.500 0.499
E13.0 With coma
0.000 0.500 0.499
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.503 0.496
M06.0 Seronegative rheumatoid arthritis
0.000 0.503 0.496
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.505 0.495
M30 Polyarteritis nodosa and related conditions
0.000 0.505 0.494
L40.1 Generalised pustular psoriasis
0.494 0.506 0.000
M22.4 Chondromalacia patellae
0.000 0.506 0.494
M86.86 Other osteomyelitis (Lower leg)
0.000 0.506 0.494
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.493 0.507 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.508 0.492
E04 Other non-toxic goitre
0.000 0.509 0.491
M93 Other osteochondropathies
0.000 0.509 0.491
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.511 0.489
E45 Retarded development following protein-energy malnutrition
0.000 0.511 0.489
E43 Unspecified severe protein-energy malnutrition
0.000 0.511 0.489
E42 Marasmic kwashiorkor
0.000 0.511 0.489
E41 Nutritional marasmus
0.000 0.511 0.489
E40 Kwashiorkor
0.000 0.511 0.489
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.000 0.511 0.489
E61.1 Iron deficiency
0.000 0.511 0.489
J45.0 Predominantly allergic asthma
0.000 0.512 0.488
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.512 0.487
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.516 0.484
M35.8 Other specified systemic involvement of connective tissue
0.000 0.521 0.479
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.000 0.522 0.478
K90.3 Pancreatic steatorrhoea
0.000 0.523 0.477
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.523 0.477
K90.1 Tropical sprue
0.000 0.523 0.477
M12.3 Palindromic rheumatism
0.000 0.524 0.476
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.524 0.476
M06.28 Rheumatoid bursitis (Other)
0.000 0.524 0.476
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.524 0.476
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.524 0.476
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.524 0.476
M06.24 Rheumatoid bursitis (Hand)
0.000 0.524 0.476
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.524 0.476
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.524 0.476
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.524 0.476
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.524 0.476
M00-M03 Infectious arthropathies
0.000 0.526 0.474
M94 Other disorders of cartilage
0.000 0.527 0.473
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.000 0.529 0.470
K90.8 Other intestinal malabsorption
0.000 0.530 0.470
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.531 0.469
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.531 0.469
M12.5 Traumatic arthropathy
0.000 0.532 0.468
M90.8 Osteopathy in other diseases classified elsewhere
0.000 0.533 0.467
M90.5 Osteonecrosis in other diseases classified elsewhere
0.000 0.533 0.467
M90.4 Osteonecrosis due to heamoglobinopathy
0.000 0.533 0.467
M90.3 Osteonecrosis in caisson disease
0.000 0.533 0.467
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.000 0.533 0.467
M90.0 Tuberculosis of bone
0.000 0.533 0.467
E54 Ascorbic acid deficiency
0.000 0.533 0.467
E13.3 With ophthalmic complications
0.000 0.534 0.466
M40-M43 Deforming dorsopathies
0.000 0.534 0.466
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.536 0.463
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.536 0.463
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.536 0.463
M09.0 Juvenile arthritis in psoriasis
0.000 0.536 0.463
M05.09 Felty's syndrome (Site unspecified)
0.000 0.537 0.463
M05.08 Felty's syndrome (Other)
0.000 0.537 0.463
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.537 0.463
M05.06 Felty's syndrome (Lower leg)
0.000 0.537 0.463
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.537 0.463
M05.04 Felty's syndrome (Hand)
0.000 0.537 0.463
M05.03 Felty's syndrome (Forearm)
0.000 0.537 0.463
M05.02 Felty's syndrome (Upper arm)
0.000 0.537 0.463
M05.01 Felty's syndrome (Shoulder region)
0.000 0.537 0.463
M05.00 Felty's syndrome (Multiple sites)
0.000 0.537 0.463
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.537 0.463
M05.18 Rheumatoid lung disease (Other)
0.000 0.537 0.463
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.537 0.463
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.537 0.463
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.537 0.463
M05.14 Rheumatoid lung disease (Hand)
0.000 0.537 0.463
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.537 0.463
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.537 0.463
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.537 0.463
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.537 0.463
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.537 0.463
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.537 0.463
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.537 0.463
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.537 0.463
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.537 0.463
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.537 0.463
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.537 0.463
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.537 0.463
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.537 0.463
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.537 0.463
M92 Other juvenile osteochondrosis
0.000 0.537 0.463
M31.6 Other giant cell arteritis
0.000 0.541 0.459
M89 Other disorders of bone
0.000 0.542 0.458
E23 Hypofunction and other disorders of pituitary gland
0.000 0.545 0.455
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.000 0.545 0.455
E46 Unspecified protein-energy malnutrition
0.000 0.546 0.454
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.547 0.452
M31.7 Microscopic polyangiitis
0.000 0.548 0.452
M08.9 Juvenile arthritis, unspecified
0.000 0.550 0.450
M08.8 Other juvenile arthritis
0.000 0.550 0.450
M08.4 Pauciarticular juvenile arthritis
0.000 0.550 0.450
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.550 0.450
M08.2 Juvenile arthritis with systemic onset
0.000 0.550 0.450
M08.1 Juvenile ankylosing spondylitis
0.000 0.550 0.450
M35.2 Behcet's disease
0.000 0.550 0.449
M90.6 Osteitis deformans in neoplastic disease
0.000 0.551 0.449
M60 Myositis
0.000 0.552 0.448
M12.4 Intermittent hydrarthrosis
0.000 0.553 0.447
M12.1 Kaschin-Beck disease
0.000 0.553 0.447
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.553 0.447
E28 Ovarian dysfunction
0.000 0.553 0.447
M22.1 Recurrent subluxation of patella
0.000 0.555 0.445
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.555 0.445
M31.2 Lethal midline granuloma
0.000 0.555 0.445
M06.18 Adult-onset Still's disease (Other)
0.000 0.555 0.444
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.555 0.444
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.555 0.444
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.555 0.444
M06.14 Adult-onset Still's disease (Hand)
0.000 0.555 0.444
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.555 0.444
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.555 0.444
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.555 0.444
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.555 0.444
E51 Thiamine deficiency
0.000 0.557 0.442
E53 Deficiency of other B group vitamins
0.000 0.559 0.441
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.560 0.440
E50 Vitamin A deficiency
0.000 0.560 0.440
E60 Dietary zinc deficiency
0.000 0.560 0.440
E59 Dietary selenium deficiency
0.000 0.560 0.440
E52 Niacin deficiency [pellagra]
0.000 0.560 0.440
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.560 0.440
C82.4 Follicular lymphoma grade IIIb
0.440 0.560 0.000
J45.1 Nonallergic asthma
0.000 0.560 0.440
H36 Retinal disorders in diseases classified elsewhere
0.000 0.560 0.439
E63 Other nutritional deficiencies
0.000 0.564 0.436
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.564 0.435
M31.8 Other specified necrotising vasculopathies
0.000 0.565 0.435
M90.79 Fracture of bone in neoplastic disease (Site unspecified)
0.000 0.567 0.433
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)
0.000 0.567 0.433
M90.76 Fracture of bone in neoplastic disease (Lower leg)
0.000 0.567 0.433
M90.74 Fracture of bone in neoplastic disease (Hand)
0.000 0.567 0.433
M90.73 Fracture of bone in neoplastic disease (Forearm)
0.000 0.567 0.433
M08.0 Juvenile rheumatoid arthritis
0.000 0.568 0.431
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.569 0.431
M36.3 Arthropathy in other blood disorders
0.000 0.569 0.431
M36.2 Haemophilic arthropathy
0.000 0.569 0.431
M36.1 Arthropathy in neoplastic disease
0.000 0.569 0.431
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.569 0.431
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.569 0.430
M22.2 Patellofemoral disorders
0.000 0.570 0.430
C82.6 Cutaneous follicle centre lymphoma
0.429 0.571 0.000
C82.5 Diffuse follicle centre lymphoma
0.429 0.571 0.000
E24 Cushing's syndrome
0.000 0.571 0.429
M13 Other arthritis
0.000 0.571 0.429
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.571 0.429
M70.2 Olecranon bursitis
0.000 0.571 0.429
L40.2 Acrodermatitis continua
0.428 0.572 0.000
M75.8 Other shoulder lesions
0.000 0.575 0.425
M94.8 Other specified disorders of cartilage
0.000 0.576 0.424
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.577 0.423
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.577 0.422
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.578 0.422
M70.4 Prepatellar bursitis
0.000 0.578 0.422
L40.8 Other psoriasis
0.421 0.579 0.000
M21.6 Other acquired deformities of ankle and foot
0.000 0.579 0.421
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.000 0.579 0.421
L40.4 Guttate psoriasis
0.420 0.580 0.000
E29 Testicular dysfunction
0.000 0.583 0.417
M21.8 Other specified acquired deformities of limbs
0.000 0.585 0.415
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.585 0.414
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.585 0.414
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.585 0.414
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.585 0.414
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.585 0.414
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.585 0.414
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.585 0.414
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.585 0.414
C82.2 Large cell, follicular
0.413 0.587 0.000
M31.0 Hypersensitivity angiitis
0.000 0.587 0.413
E04.0 Non-toxic diffuse goitre
0.000 0.588 0.412
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.000 0.590 0.410
M31.9 Necrotising vasculopathy, unspecified
0.000 0.590 0.410
J41 Simple and mucopurulent chronic bronchitis
0.000 0.590 0.410
M94.86 Other specified disorders of cartilage (Lower leg)
0.000 0.590 0.410
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.591 0.409
M14.6 Neuropathic arthropathy
0.000 0.592 0.408
M86.89 Other osteomyelitis (Site unspecified)
0.000 0.592 0.408
M86.88 Other osteomyelitis (Other)
0.000 0.592 0.408
M86.84 Other osteomyelitis (Hand)
0.000 0.592 0.408
M86.83 Other osteomyelitis (Forearm)
0.000 0.592 0.408
M86.82 Other osteomyelitis (Upper arm)
0.000 0.592 0.408
M86.81 Other osteomyelitis (Shoulder region)
0.000 0.592 0.408
M86.80 Other osteomyelitis (Multiple sites)
0.000 0.592 0.408
M86.69 Other chronic osteomyelitis (Site unspecified)
0.000 0.593 0.407
M86.68 Other chronic osteomyelitis (Other)
0.000 0.593 0.407
M86.64 Other chronic osteomyelitis (Hand)
0.000 0.593 0.407
M86.63 Other chronic osteomyelitis (Forearm)
0.000 0.593 0.407
M86.62 Other chronic osteomyelitis (Upper arm)
0.000 0.593 0.407
M86.61 Other chronic osteomyelitis (Shoulder region)
0.000 0.593 0.407
M86.60 Other chronic osteomyelitis (Multiple sites)
0.000 0.593 0.407
M10.0 Idiopathic gout
0.000 0.593 0.407
E28.3 Primary ovarian failure
0.000 0.594 0.406
M21.9 Acquired deformity of limb, unspecified
0.000 0.596 0.404
J43.1 Panlobular emphysema
0.000 0.597 0.403
J43.0 MacLeod's syndrome
0.000 0.597 0.403
E23.2 Diabetes insipidus
0.000 0.597 0.403
E07.1 Dyshormogenetic goitre
0.000 0.597 0.403
E07.0 Hypersecretion of calcitonin
0.000 0.597 0.403
M93.9 Osteochondropathy, unspecified
0.000 0.597 0.403
L40.3 Pustulosis palmaris et plantaris
0.402 0.598 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.598 0.402
M14.4 Arthropathy in amyloidosis
0.000 0.598 0.402
M14.3 Lipoid dermatoarthritis
0.000 0.598 0.402
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.598 0.402
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.598 0.402
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.000 0.598 0.402
M21.48 Flat foot [pes planus] (acquired)-Other
0.000 0.598 0.402
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.000 0.598 0.402
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.000 0.598 0.402
M21.44 Flat foot [pes planus] (acquired)-Hand
0.000 0.598 0.402
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.000 0.598 0.402
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.000 0.598 0.402
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.000 0.598 0.402
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.000 0.598 0.402
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.599 0.401
J45.8 Mixed asthma
0.000 0.602 0.398
M89.8 Other specified disorders of bone
0.000 0.602 0.398
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.602 0.398
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)
0.000 0.603 0.397
E56 Other vitamin deficiencies
0.001 0.603 0.396
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.604 0.396
E32 Diseases of thymus
0.000 0.604 0.396
E30 Disorders of puberty, not elsewhere classified
0.000 0.604 0.396
M05.28 Rheumatoid vasculitis (Other)
0.000 0.604 0.395
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.604 0.395
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.604 0.395
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.604 0.395
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.604 0.395
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.604 0.395
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.604 0.395
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.604 0.395
M90.1 Periostitis in other infectious diseases classified elsewhere
0.000 0.605 0.394
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.607 0.393
M61 Calcification and ossification of muscle
0.000 0.607 0.393
E07.8 Other specified disorders of thyroid
0.000 0.608 0.392

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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