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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs154989
log Bayes Factor = 122.33
Chromosome 6   position 32,877,173  (GRCh37) Explore rs154989 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
M35.3 Polymyalgia rheumatica
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.004 0.996
E10.2 With renal complications
0.000 0.010 0.990
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.014 0.986
E14.3 With ophthalmic complications
0.000 0.017 0.983
E10.8 With unspecified complications
0.000 0.017 0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.019 0.981
E10.5 With peripheral circulatory complications
0.000 0.032 0.968
E10.0 With coma
0.000 0.037 0.963
H36.0 Diabetic retinopathy
0.000 0.046 0.954
J33.0 Polyp of nasal cavity
0.000 0.052 0.948
E11 Non-insulin-dependent diabetes mellitus
0.000 0.055 0.945
J33 Nasal polyp
0.000 0.065 0.935
E06 Thyroiditis
0.000 0.073 0.927
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.073 0.927
J33.9 Nasal polyp, unspecified
0.000 0.075 0.925
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.102 0.898
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.107 0.893
E14.9 Without complications
0.000 0.113 0.887
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.115 0.885
M06 Other rheumatoid arthritis
0.000 0.148 0.852
J33.8 Other polyp of sinus
0.000 0.151 0.849
E10.6 With other specified complications
0.000 0.155 0.845
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.168 0.832
E11.2 With renal complications
0.000 0.169 0.831
E11.1 With ketoacidosis
0.000 0.178 0.822
E14.8 With unspecified complications
0.000 0.186 0.814
E06.3 Autoimmune thyroiditis
0.000 0.186 0.814
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.193 0.807
M05 Seropositive rheumatoid arthritis
0.000 0.196 0.804
M05-M14 Inflammatory polyarthropathies
0.000 0.196 0.804
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.199 0.801
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.204 0.796
E14.6 With other specified complications
0.000 0.204 0.796
E14.1 With ketoacidosis
0.000 0.208 0.792
E11.5 With peripheral circulatory complications
0.000 0.222 0.778
L40.9 Psoriasis, unspecified
0.775 0.225 0.000
E11.3 With ophthalmic complications
0.000 0.232 0.768
E06.9 Thyroiditis, unspecified
0.000 0.237 0.763
E11.9 Without complications
0.000 0.243 0.757
E11.6 With other specified complications
0.000 0.247 0.753
J33.1 Polypoid sinus degeneration
0.000 0.276 0.724
E06.5 Other chronic thyroiditis
0.000 0.277 0.723
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.285 0.714
E14.0 With coma
0.000 0.285 0.714
E14.5 With peripheral circulatory complications
0.000 0.286 0.714
E13 Other specified diabetes mellitus
0.000 0.292 0.707
M35 Other systemic involvement of connective tissue
0.000 0.296 0.704
M06.4 Inflammatory polyarthropathy
0.000 0.298 0.702
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.299 0.700
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.303 0.697
E03.1 Congenital hypothyroidism without goitre
0.000 0.303 0.696
K90 Intestinal malabsorption
0.000 0.304 0.696
E40-E46 Malnutrition
0.000 0.308 0.692
E03.8 Other specified hypothyroidism
0.000 0.313 0.687
E06.1 Subacute thyroiditis
0.000 0.322 0.678
E11.7 With multiple complications
0.000 0.322 0.677
J45 Asthma
0.000 0.325 0.675
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.329 0.671
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.330 0.670
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.333 0.667
E06.4 Drug-induced thyroiditis
0.000 0.335 0.665
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.335 0.665
E06.0 Acute thyroiditis
0.000 0.335 0.665
E14.2 Withrenal complications
0.000 0.339 0.661
E50-E64 Other nutritional deficiencies
0.000 0.348 0.652
E14.4 With neurological complications
0.000 0.355 0.645
E11.8 With unspecified complications
0.000 0.375 0.625
M05.8 Other seropositive rheumatoid arthritis
0.000 0.375 0.625
M20-M25 Other joint disorders
0.000 0.388 0.612
E05.8 Other thyrotoxicosis
0.000 0.389 0.611
M06.2 Rheumatoid bursitis
0.000 0.389 0.611
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.604 0.396 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.396 0.603
L40 Psoriasis
0.600 0.400 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.401 0.599
K90.9 Intestinal malabsorption, unspecified
0.000 0.401 0.599
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.405 0.595
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.408 0.592
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.409 0.591
M86-M90 Other osteopathies
0.000 0.415 0.585
E20-E35 Disorders of other endocrine glands
0.000 0.419 0.581
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.421 0.579
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.423 0.577
M05.1 Rheumatoid lung disease
0.000 0.423 0.577
M05.0 Felty's syndrome
0.000 0.423 0.577
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.423 0.577
M86 Osteomyelitis
0.000 0.423 0.577
E61 Deficiency of other nutrient elements
0.000 0.425 0.575
M34 Systemic sclerosis
0.000 0.427 0.573
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.428 0.571
M06.1 Adult-onset Still's disease
0.000 0.429 0.571
M86.9 Osteomyelitis, unspecified
0.000 0.430 0.570
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.431 0.569
M35.7 Hypermobility syndrome
0.000 0.431 0.568
L40.5 Arthropathic psoriasis
0.568 0.432 0.000
M32 Systemic lupus erythematosus
0.000 0.440 0.560
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.440 0.560
M08 Juvenile arthritis
0.000 0.440 0.560
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.443 0.557
M12 Other specific arthropathies
0.000 0.447 0.553
J40-J47 Chronic lower respiratory diseases
0.000 0.462 0.538
E07 Other disorders of thyroid
0.000 0.464 0.536
J44 Other chronic obstructive pulmonary disease
0.000 0.467 0.533
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.468 0.531
M06.8 Other specified rheumatoid arthritis
0.000 0.468 0.531
E13.9 Without complications
0.000 0.471 0.529
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.473 0.527
E61.1 Iron deficiency
0.000 0.473 0.527
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.483 0.517
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.485 0.515
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M35.0 Sicca syndrome [Sjogren]
0.000 0.486 0.514
J43 Emphysema
0.000 0.486 0.514
E16.1 Other hypoglycaemia
0.000 0.487 0.513
M34.1 CR(E)ST syndrome
0.000 0.491 0.509
J45.0 Predominantly allergic asthma
0.000 0.491 0.509
M90 Osteopathies in diseases classified elsewhere
0.000 0.492 0.507
E13.8 With unspecified complications
0.000 0.493 0.507
E13.7 With multiple complications
0.000 0.493 0.507
E13.6 With other specified complications
0.000 0.493 0.507
E13.5 With peripheral circulatory complications
0.000 0.493 0.507
E13.4 With neurological complications
0.000 0.493 0.507
E13.2 With renal complications
0.000 0.493 0.507
E13.1 With ketoacidosis
0.000 0.493 0.507
E13.0 With coma
0.000 0.493 0.507
M06.3 Rheumatoid nodule
0.000 0.493 0.507
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.506 0.494 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.495 0.505
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.495 0.505
M35.5 Multifocal fibrosclerosis
0.000 0.495 0.505
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.495 0.505
J43.9 Emphysema, unspecified
0.000 0.495 0.505
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.497 0.503
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.497 0.503
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.497 0.503
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.497 0.503
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.497 0.503
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.497 0.503
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.497 0.503
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.499 0.501
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.499 0.501
K90.3 Pancreatic steatorrhoea
0.000 0.501 0.499
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.501 0.499
K90.1 Tropical sprue
0.000 0.501 0.499
L40.1 Generalised pustular psoriasis
0.497 0.503 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.503 0.497
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.504 0.496
E45 Retarded development following protein-energy malnutrition
0.000 0.504 0.496
E43 Unspecified severe protein-energy malnutrition
0.000 0.504 0.496
E42 Marasmic kwashiorkor
0.000 0.504 0.496
E41 Nutritional marasmus
0.000 0.504 0.496
E40 Kwashiorkor
0.000 0.504 0.496
E54 Ascorbic acid deficiency
0.000 0.504 0.496
M14 Arthropathies in other diseases classified elsewhere
0.000 0.504 0.495
M05.2 Rheumatoid vasculitis
0.000 0.508 0.492
E53 Deficiency of other B group vitamins
0.000 0.510 0.490
E11.0 With coma
0.000 0.510 0.490
K90.8 Other intestinal malabsorption
0.000 0.510 0.490
M31 Other necrotising vasculopathies
0.000 0.517 0.483
M11 Other crystal arthropathies
0.000 0.518 0.482
M21 Other acquired deformities of limbs
0.000 0.520 0.480
E13.3 With ophthalmic complications
0.000 0.527 0.473
M90.7 Fracture of bone in neoplastic disease
0.000 0.528 0.472
E46 Unspecified protein-energy malnutrition
0.000 0.529 0.471
E04 Other non-toxic goitre
0.000 0.529 0.471
E51 Thiamine deficiency
0.000 0.530 0.469
C82.0 Small cleaved cell, follicular
0.468 0.532 0.000
M34.8 Other forms of systemic sclerosis
0.000 0.532 0.468
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.532 0.467
E50 Vitamin A deficiency
0.000 0.532 0.467
E60 Dietary zinc deficiency
0.000 0.532 0.467
E59 Dietary selenium deficiency
0.000 0.532 0.467
E52 Niacin deficiency [pellagra]
0.000 0.532 0.467
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.533 0.467
E11.4 With neurological complications
0.000 0.533 0.467
E28 Ovarian dysfunction
0.000 0.535 0.465
E23 Hypofunction and other disorders of pituitary gland
0.000 0.535 0.465
E63 Other nutritional deficiencies
0.000 0.536 0.463
M06.0 Seronegative rheumatoid arthritis
0.000 0.537 0.463
M91-M94 Chondropathies
0.000 0.539 0.461
M10 Gout
0.000 0.539 0.460
M22 Disorders of patella
0.000 0.541 0.459
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.547 0.453
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.549 0.450
M75 Shoulder lesions
0.000 0.550 0.450
M34.0 Progressive systemic sclerosis
0.000 0.551 0.449
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.552 0.448
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.552 0.448
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.552 0.448
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.552 0.448
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.552 0.448
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.552 0.448
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.552 0.448
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.552 0.448
H36 Retinal disorders in diseases classified elsewhere
0.000 0.552 0.447
E24 Cushing's syndrome
0.000 0.553 0.447
M75.3 Calcific tendinitis of shoulder
0.000 0.554 0.446
M70-M79 Other soft tissue disorders
0.000 0.554 0.446
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.556 0.444
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.559 0.441
M86.8 Other osteomyelitis
0.000 0.560 0.440
M86.6 Other chronic osteomyelitis
0.000 0.562 0.438
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.562 0.438
M06.28 Rheumatoid bursitis (Other)
0.000 0.562 0.438
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.562 0.438
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.562 0.438
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.562 0.438
M06.24 Rheumatoid bursitis (Hand)
0.000 0.562 0.438
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.562 0.438
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.562 0.438
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.562 0.438
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.562 0.438
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.563 0.437
M35.1 Other overlap syndromes
0.000 0.566 0.434
M21.4 Flat foot [pes planus] (acquired)
0.000 0.568 0.431
M34.9 Systemic sclerosis, unspecified
0.000 0.570 0.430
L40.2 Acrodermatitis continua
0.430 0.570 0.000
C82.3 Follicular lymphoma grade IIIa
0.430 0.570 0.000
M60-M63 Disorders of muscles
0.000 0.571 0.429
J45.1 Nonallergic asthma
0.000 0.574 0.426
L40.8 Other psoriasis
0.425 0.575 0.000
M32.8 Other forms of systemic lupus erythematosus
0.000 0.575 0.425
E29 Testicular dysfunction
0.000 0.576 0.424
L40.4 Guttate psoriasis
0.422 0.577 0.000
E28.3 Primary ovarian failure
0.000 0.578 0.422
M12.3 Palindromic rheumatism
0.000 0.578 0.422
M21.0 Valgus deformity, not elsewhere classified
0.000 0.579 0.421
E56 Other vitamin deficiencies
0.001 0.579 0.421
M90.78 Fracture of bone in neoplastic disease (Other)
0.000 0.581 0.419
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.583 0.416
E32 Diseases of thymus
0.000 0.583 0.416
E30 Disorders of puberty, not elsewhere classified
0.000 0.583 0.416
M12.5 Traumatic arthropathy
0.000 0.585 0.415
M88 Paget's disease of bone [osteitis deformans]
0.000 0.585 0.415
M05.09 Felty's syndrome (Site unspecified)
0.000 0.586 0.413
M05.08 Felty's syndrome (Other)
0.000 0.586 0.413
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.586 0.413
M05.06 Felty's syndrome (Lower leg)
0.000 0.586 0.413
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.586 0.413
M05.04 Felty's syndrome (Hand)
0.000 0.586 0.413
M05.03 Felty's syndrome (Forearm)
0.000 0.586 0.413
M05.02 Felty's syndrome (Upper arm)
0.000 0.586 0.413
M05.01 Felty's syndrome (Shoulder region)
0.000 0.586 0.413
M05.00 Felty's syndrome (Multiple sites)
0.000 0.586 0.413
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.586 0.413
M05.18 Rheumatoid lung disease (Other)
0.000 0.586 0.413
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.586 0.413
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.586 0.413
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.586 0.413
M05.14 Rheumatoid lung disease (Hand)
0.000 0.586 0.413
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.586 0.413
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.586 0.413
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.586 0.413
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.586 0.413
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.586 0.413
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.586 0.413
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.586 0.413
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.586 0.413
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.586 0.413
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.586 0.413
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.586 0.413
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.586 0.413
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.586 0.413
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.586 0.413
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.586 0.413
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.586 0.413
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.586 0.413
M09.0 Juvenile arthritis in psoriasis
0.000 0.586 0.413
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.586 0.413
M86.3 Chronic multifocal osteomyelitis
0.000 0.586 0.413
M86.2 Subacute osteomyelitis
0.000 0.586 0.413
M86.0 Acute haematogenous osteomyelitis
0.000 0.586 0.413
E61.9 Deficiency of nutrient element, unspecified
0.000 0.587 0.412
E61.8 Deficiency of other specified nutrient elements
0.000 0.587 0.412
E61.7 Deficiency of multiple nutrient elements
0.000 0.587 0.412
E61.6 Vanadium deficiency
0.000 0.587 0.412
E61.5 Molybdenum deficiency
0.000 0.587 0.412
E61.4 Chromium deficiency
0.000 0.587 0.412
E61.3 Manganese deficiency
0.000 0.587 0.412
E61.0 Copper deficiency
0.000 0.587 0.412
E20 Hypoparathyroidism
0.000 0.589 0.411
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.589 0.411
E26 Hyperaldosteronism
0.000 0.590 0.410
E23.2 Diabetes insipidus
0.000 0.590 0.410
M06.18 Adult-onset Still's disease (Other)
0.000 0.591 0.409
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.591 0.409
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.591 0.409
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.591 0.409
M06.14 Adult-onset Still's disease (Hand)
0.000 0.591 0.409
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.591 0.409
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.591 0.409
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.591 0.409
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.591 0.409
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.591 0.409
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.591 0.409
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.591 0.409
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.591 0.409
M75.9 Shoulder lesion, unspecified
0.000 0.592 0.408
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.593 0.407
M86.1 Other acute osteomyelitis
0.000 0.593 0.407
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.407 0.593 0.000
L40.3 Pustulosis palmaris et plantaris
0.405 0.595 0.000
E27 Other disorders of adrenal gland
0.000 0.596 0.404
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.598 0.402
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.598 0.402
M08.9 Juvenile arthritis, unspecified
0.000 0.598 0.401
M08.8 Other juvenile arthritis
0.000 0.598 0.401
M08.4 Pauciarticular juvenile arthritis
0.000 0.598 0.401
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.598 0.401
M08.2 Juvenile arthritis with systemic onset
0.000 0.598 0.401
M08.1 Juvenile ankylosing spondylitis
0.000 0.598 0.401
M21.1 Varus deformity, not elsewhere classified
0.000 0.601 0.399
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.601 0.399
M75.0 Adhesive capsulitis of shoulder
0.000 0.602 0.398
M35.8 Other specified systemic involvement of connective tissue
0.000 0.603 0.397
M12.4 Intermittent hydrarthrosis
0.000 0.603 0.397
M12.1 Kaschin-Beck disease
0.000 0.603 0.397
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.603 0.397
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.603 0.397
E25 Adrenogenital disorders
0.000 0.605 0.395
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.605 0.395
E53.9 Vitamin B deficiency, unspecified
0.000 0.606 0.394
E04.0 Non-toxic diffuse goitre
0.000 0.606 0.394
M75.2 Bicipital tendinitis
0.000 0.607 0.393
E61.2 Magnesium deficiency
0.000 0.608 0.392
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.610 0.390
E27.1 Primary adrenocortical insufficiency
0.000 0.612 0.388
E31 Polyglandular dysfunction
0.000 0.612 0.388
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.612 0.388
J45.8 Mixed asthma
0.000 0.614 0.386
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.614 0.386
J41 Simple and mucopurulent chronic bronchitis
0.000 0.614 0.386
M08.0 Juvenile rheumatoid arthritis
0.000 0.615 0.385
E07.1 Dyshormogenetic goitre
0.000 0.615 0.385
E07.0 Hypersecretion of calcitonin
0.000 0.615 0.385
M22.0 Recurrent dislocation of patella
0.000 0.617 0.383
E22 Hyperfunction of pituitary gland
0.000 0.617 0.383
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.618 0.382
M30 Polyarteritis nodosa and related conditions
0.000 0.618 0.382
M86.86 Other osteomyelitis (Lower leg)
0.000 0.619 0.381
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.619 0.381
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.619 0.381
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.619 0.381
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.619 0.381
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.619 0.381
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.619 0.381
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.619 0.381
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.619 0.381
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.000 0.619 0.381
M75.4 Impingement syndrome of shoulder
0.000 0.619 0.381
E23.7 Disorder of pituitary gland, unspecified
0.000 0.619 0.381
M13 Other arthritis
0.000 0.622 0.378
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.622 0.377
M22.9 Disorder of patella, unspecified
0.000 0.624 0.376
M35.2 Behcet's disease
0.000 0.627 0.372
C82.4 Follicular lymphoma grade IIIb
0.372 0.628 0.000
E07.8 Other specified disorders of thyroid
0.000 0.628 0.372
M00-M03 Infectious arthropathies
0.000 0.631 0.369
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.631 0.369
J43.1 Panlobular emphysema
0.000 0.631 0.368
J43.0 MacLeod's syndrome
0.000 0.631 0.368
M93 Other osteochondropathies
0.000 0.633 0.366
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.000 0.635 0.365
M89 Other disorders of bone
0.000 0.636 0.364
M90.8 Osteopathy in other diseases classified elsewhere
0.000 0.636 0.364
M90.5 Osteonecrosis in other diseases classified elsewhere
0.000 0.636 0.364
M90.4 Osteonecrosis due to heamoglobinopathy
0.000 0.636 0.364
M90.3 Osteonecrosis in caisson disease
0.000 0.636 0.364
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.000 0.636 0.364
M90.0 Tuberculosis of bone
0.000 0.636 0.364
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.636 0.364
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.636 0.364
M06.38 Rheumatoid nodule (Other)
0.000 0.636 0.364
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.636 0.364
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.636 0.364
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.636 0.364
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.000 0.637 0.363
C82.6 Cutaneous follicle centre lymphoma
0.362 0.637 0.000
C82.5 Diffuse follicle centre lymphoma
0.362 0.637 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.638 0.362
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.639 0.361
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.641 0.359
M10.0 Idiopathic gout
0.000 0.641 0.359
M14.6 Neuropathic arthropathy
0.000 0.641 0.358
M31.6 Other giant cell arteritis
0.000 0.642 0.358
M11.9 Crystal arthropathy, unspecified
0.000 0.644 0.356
E44.1 Mild protein-energy malnutrition
0.000 0.644 0.356
E44.0 Moderate protein-energy malnutrition
0.000 0.644 0.356
M22.4 Chondromalacia patellae
0.000 0.644 0.356
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.645 0.355
M14.4 Arthropathy in amyloidosis
0.000 0.645 0.355
M14.3 Lipoid dermatoarthritis
0.000 0.645 0.355
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.645 0.355
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.645 0.355
E24.2 Drug-induced Cushing's syndrome
0.000 0.645 0.355
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.000 0.645 0.355
M60 Myositis
0.000 0.646 0.354
M05.28 Rheumatoid vasculitis (Other)
0.000 0.647 0.353
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.647 0.353
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.647 0.353
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.647 0.353
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.647 0.353
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.647 0.353
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.647 0.353
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.647 0.353
E53.1 Pyridoxine deficiency
0.000 0.648 0.351
E53.0 Riboflavin deficiency
0.000 0.648 0.351
M31.7 Microscopic polyangiitis
0.000 0.648 0.352
C82.2 Large cell, follicular
0.350 0.650 0.000
M90.6 Osteitis deformans in neoplastic disease
0.000 0.651 0.349
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.651 0.349
M94 Other disorders of cartilage
0.000 0.653 0.347
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.653 0.346
M31.2 Lethal midline granuloma
0.000 0.653 0.346
M92 Other juvenile osteochondrosis
0.000 0.654 0.346
M11.1 Familial chondrocalcinosis
0.000 0.654 0.345
M11.0 Hydroxyapatite deposition disease
0.000 0.654 0.345
E23.6 Other disorders of pituitary gland
0.000 0.654 0.345
J42 Unspecified chronic bronchitis
0.000 0.656 0.344
M40-M43 Deforming dorsopathies
0.000 0.656 0.344
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.658 0.342
M07 Psoriatic and enteropathic arthropathies
0.001 0.661 0.338
E51.2 Wernicke's encephalopathy
0.000 0.661 0.339
J43.8 Other emphysema
0.000 0.661 0.338
M31.8 Other specified necrotising vasculopathies
0.000 0.661 0.338
M90.79 Fracture of bone in neoplastic disease (Site unspecified)
0.000 0.662 0.338
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)
0.000 0.662 0.338
M90.76 Fracture of bone in neoplastic disease (Lower leg)
0.000 0.662 0.338
M90.74 Fracture of bone in neoplastic disease (Hand)
0.000 0.662 0.338
M90.73 Fracture of bone in neoplastic disease (Forearm)
0.000 0.662 0.338
E04.8 Other specified non-toxic goitre
0.000 0.662 0.338
E51.9 Thiamine deficiency, unspecified
0.000 0.663 0.337
E51.8 Other manifestations of thiamine deficiency
0.000 0.663 0.337
E51.1 Beriberi
0.000 0.663 0.337
E50.9 Vitamin A deficiency, unspecified
0.000 0.664 0.335
E50.8 Other manifestations of vitamin A deficiency
0.000 0.664 0.335
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.664 0.335
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.664 0.335
E50.5 Vitamin A deficiency with night blindness
0.000 0.664 0.335
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.664 0.335
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.664 0.335
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.664 0.335
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.664 0.335

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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