TreeWAS – Variant ID: rs1564282

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.56 Pain in joint (Lower leg)	0.000	0.768	0.232
M25.5 Pain in joint	0.000	0.768	0.232
M25.57 Pain in joint (Ankle and foot)	0.000	0.770	0.230
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.780	0.220
M25 Other joint disorders, not elsewhere classified	0.000	0.801	0.199
M25.53 Pain in joint (Forearm)	0.000	0.804	0.196
M25.7 Osteophyte	0.000	0.809	0.191
M25.52 Pain in joint (Upper arm)	0.000	0.829	0.171
M25.78 Osteophyte (Other)	0.000	0.832	0.168
M25.72 Osteophyte (Upper arm)	0.000	0.835	0.165
M25.54 Pain in joint (Hand)	0.000	0.835	0.165
M25.9 Joint disorder, unspecified	0.000	0.836	0.164
M25.74 Osteophyte (Hand)	0.000	0.838	0.162
M25.0 Haemarthrosis	0.000	0.842	0.158
M25.8 Other specified joint disorders	0.000	0.845	0.155
M25.76 Osteophyte (Lower leg)	0.000	0.851	0.149
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.856	0.144
M25.2 Flail joint	0.000	0.857	0.142
M25.1 Fistula of joint	0.000	0.857	0.142
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.859	0.141
M25.58 Pain in joint (Other)	0.000	0.859	0.141
M25.79 Osteophyte (Site unspecified)	0.000	0.863	0.137
M25.73 Osteophyte (Forearm)	0.000	0.863	0.137
M25.70 Osteophyte (Multiple sites)	0.000	0.863	0.137
M25.77 Osteophyte (Ankle and foot)	0.000	0.864	0.136
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.866	0.133
M25.06 Haemarthrosis (Lower leg)	0.000	0.871	0.129
M25.4 Effusion of joint	0.000	0.873	0.127
M25.3 Other instability of joint	0.000	0.873	0.127
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.880	0.120
M25.84 Other specified joint disorders (Hand)	0.000	0.882	0.118
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.882	0.117
M25.98 Joint disorder, unspecified (Other)	0.000	0.882	0.117
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.882	0.117
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.882	0.117
M25.94 Joint disorder, unspecified (Hand)	0.000	0.882	0.117
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.882	0.117
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.882	0.117
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.882	0.117
M25.71 Osteophyte (Shoulder region)	0.000	0.884	0.116
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.886	0.114
M25.09 Haemarthrosis (Site unspecified)	0.000	0.887	0.113
M25.08 Haemarthrosis (Other)	0.000	0.887	0.113
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.887	0.113
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.887	0.113
M25.04 Haemarthrosis (Hand)	0.000	0.887	0.113
M25.03 Haemarthrosis (Forearm)	0.000	0.887	0.113
M25.02 Haemarthrosis (Upper arm)	0.000	0.887	0.113
M25.01 Haemarthrosis (Shoulder region)	0.000	0.887	0.113
M25.00 Haemarthrosis (Multiple sites)	0.000	0.887	0.113
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.887	0.113
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.889	0.111
M25.83 Other specified joint disorders (Forearm)	0.000	0.889	0.111
M25.82 Other specified joint disorders (Upper arm)	0.000	0.889	0.111
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.889	0.111
M25.50 Pain in joint (Multiple sites)	0.000	0.890	0.110
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.894	0.106
M25.88 Other specified joint disorders (Other)	0.000	0.894	0.106
M25.47 Effusion of joint (Ankle and foot)	0.000	0.895	0.105
M25.19 Fistula of joint (Site unspecified)	0.000	0.898	0.102
M25.18 Fistula of joint (Other)	0.000	0.898	0.102
M25.17 Fistula of joint (Ankle and foot)	0.000	0.898	0.102
M25.16 Fistula of joint (Lower leg)	0.000	0.898	0.102
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.898	0.102
M25.14 Fistula of joint (Hand)	0.000	0.898	0.102
M25.13 Fistula of joint (Forearm)	0.000	0.898	0.102
M25.12 Fistula of joint (Upper arm)	0.000	0.898	0.102
M25.11 Fistula of joint (Shoulder region)	0.000	0.898	0.102
M25.10 Fistula of joint (Multiple sites)	0.000	0.898	0.102
M25.29 Flail joint (Site unspecified)	0.000	0.898	0.102
M25.28 Flail joint (Other)	0.000	0.898	0.102
M25.27 Flail joint (Ankle and foot)	0.000	0.898	0.102
M25.26 Flail joint (Lower leg)	0.000	0.898	0.102
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.898	0.102
M25.24 Flail joint (Hand)	0.000	0.898	0.102
M25.23 Flail joint (Forearm)	0.000	0.898	0.102
M25.22 Flail joint (Upper arm)	0.000	0.898	0.102
M25.21 Flail joint (Shoulder region)	0.000	0.898	0.102
M25.20 Flail joint (Multiple sites)	0.000	0.898	0.102
M25.37 Other instability of joint (Ankle and foot)	0.000	0.902	0.098
M25.51 Pain in joint (Shoulder region)	0.000	0.905	0.095
M25.59 Pain in joint (Site unspecified)	0.001	0.908	0.092
M25.39 Other instability of joint (Site unspecified)	0.000	0.909	0.091
M25.38 Other instability of joint (Other)	0.000	0.909	0.091
M25.36 Other instability of joint (Lower leg)	0.000	0.909	0.091
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.909	0.091
M25.33 Other instability of joint (Forearm)	0.000	0.909	0.091
M25.32 Other instability of joint (Upper arm)	0.000	0.909	0.091
M25.30 Other instability of joint (Multiple sites)	0.000	0.909	0.091
M25.49 Effusion of joint (Site unspecified)	0.000	0.909	0.091
M25.48 Effusion of joint (Other)	0.000	0.909	0.091
M25.44 Effusion of joint (Hand)	0.000	0.909	0.091
M25.43 Effusion of joint (Forearm)	0.000	0.909	0.091
M25.42 Effusion of joint (Upper arm)	0.000	0.909	0.091
M25.41 Effusion of joint (Shoulder region)	0.000	0.909	0.091
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.911	0.089
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.912	0.088
M25.46 Effusion of joint (Lower leg)	0.000	0.913	0.087
M25.31 Other instability of joint (Shoulder region)	0.000	0.913	0.086
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.913	0.086
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.913	0.086
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.913	0.086
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.913	0.086
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.913	0.086
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.918	0.081
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.921	0.078
M25.86 Other specified joint disorders (Lower leg)	0.000	0.922	0.077
M25.40 Effusion of joint (Multiple sites)	0.000	0.924	0.076
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.924	0.076
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.925	0.075
M25.34 Other instability of joint (Hand)	0.000	0.928	0.071
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.990	0.010
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.991	0.009
M23.3 Other meniscus derangements	0.000	0.991	0.009
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.992	0.008
M23.37 Other meniscus derangements-Capsular lig	0.000	0.994	0.006
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.994	0.006
M23 Internal derangement of knee	0.000	0.994	0.006
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
M20-M25 Other joint disorders	0.000	0.994	0.006
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.994	0.006
C44.7 Skin of lower limb, including hip	0.000	0.994	0.006
K51.9 Ulcerative colitis, unspecified	0.000	0.994	0.006
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.995	0.005
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.995	0.005
M33 Dermatopolymyositis	0.000	0.995	0.005
M23.0 Cystic meniscus	0.000	0.995	0.005
M23.9 Internal derangement of knee, unspecified	0.000	0.995	0.005
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.995	0.005
M23.1 Discoid meniscus (congenital)	0.000	0.995	0.004
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.995	0.005
M32 Systemic lupus erythematosus	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
M22.4 Chondromalacia patellae	0.000	0.996	0.004
M22 Disorders of patella	0.000	0.996	0.004
M23.4 Loose body in knee	0.000	0.996	0.004
M30 Polyarteritis nodosa and related conditions	0.000	0.996	0.004
K51.8 Other ulcerative colitis	0.000	0.996	0.004
M31 Other necrotising vasculopathies	0.000	0.996	0.004
M23.5 Chronic instability of knee	0.000	0.996	0.004
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.996	0.004
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.004	0.996	0.000
K51 Ulcerative colitis	0.000	0.996	0.004
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
K60.2 Anal fissure, unspecified	0.000	0.996	0.004
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.996	0.004
M33.2 Polymyositis	0.000	0.996	0.004
K51.2 Ulcerative (chronic) proctitis	0.000	0.996	0.004
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.996	0.004
M33.1 Other dermatomyositis	0.000	0.996	0.004
M21 Other acquired deformities of limbs	0.000	0.996	0.004
M33.9 Dermatopolymyositis, unspecified	0.000	0.996	0.003
M33.0 Juvenile dermatomyositis	0.000	0.996	0.003
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.003
M23.07 Cystic meniscus-Capsular lig	0.000	0.996	0.003
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.996	0.003
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.003
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.996	0.003
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.996	0.003
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.003
M23.00 Cystic meniscus (Multiple sites)	0.000	0.996	0.003
E07.9 Disorder of thyroid, unspecified	0.000	0.996	0.004
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.003
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.996	0.003
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.996	0.003
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.996	0.003
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.003
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.996	0.003
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.996	0.003
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.003
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.996	0.003
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.996	0.003
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.996	0.003
M36.3 Arthropathy in other blood disorders	0.000	0.996	0.003
M36.2 Haemophilic arthropathy	0.000	0.996	0.003
M36.1 Arthropathy in neoplastic disease	0.000	0.996	0.003
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.996	0.003
N43.3 Hydrocele, unspecified	0.000	0.996	0.004
M22.3 Other derangements of patella	0.000	0.996	0.003
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.003
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.996	0.003
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.996	0.003
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.003
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.996	0.003
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.996	0.003
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.003
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.996	0.003
M34 Systemic sclerosis	0.000	0.996	0.003
M31.3 Wegener's granulomatosis	0.000	0.996	0.003
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.996	0.004
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.003	0.996	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.996	0.003
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.997	0.003
M32.8 Other forms of systemic lupus erythematosus	0.000	0.997	0.003
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.997	0.003
M22.1 Recurrent subluxation of patella	0.000	0.997	0.003
M22.0 Recurrent dislocation of patella	0.000	0.997	0.003
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M23.47 Loose body in knee-Capsular lig	0.000	0.997	0.003
M23.46 Loose body in knee-O/unsp lat men	0.000	0.997	0.003
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.997	0.003
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.997	0.003
M23.43 Loose body in knee-Med lig/oth men	0.000	0.997	0.003
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.997	0.003
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.997	0.003
M23.40 Loose body in knee-Mult sites	0.000	0.997	0.003
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.997	0.003
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.997	0.003
M30.2 Juvenile polyarteritis	0.000	0.997	0.003
M30.0 Polyarteritis nodosa	0.000	0.997	0.003
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.997	0.003
M31.9 Necrotising vasculopathy, unspecified	0.000	0.997	0.003
M31.8 Other specified necrotising vasculopathies	0.000	0.997	0.003
M31.7 Microscopic polyangiitis	0.000	0.997	0.003
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.997	0.003
M31.2 Lethal midline granuloma	0.000	0.997	0.003
M31.1 Thrombotic microangiopathy	0.000	0.997	0.003
M31.0 Hypersensitivity angiitis	0.000	0.997	0.003
Z86.0 Personal history of other neoplasms	0.003	0.997	0.000
M23.8 Other internal derangements of knee	0.000	0.997	0.003
N92.1 Excessive and frequent menstruation with irregular cycle	0.003	0.997	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.997	0.003
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.003
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.997	0.003
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.997	0.003
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.997	0.003
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.997	0.003
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.997	0.003
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.997	0.003
H93.1 Tinnitus	0.003	0.997	0.000
M22.9 Disorder of patella, unspecified	0.000	0.997	0.003
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.997	0.003
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.997	0.003
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
M21.9 Acquired deformity of limb, unspecified	0.000	0.997	0.003
M21.8 Other specified acquired deformities of limbs	0.000	0.997	0.003
M21.7 Unequal limb length (acquired)	0.000	0.997	0.003
M21.0 Valgus deformity, not elsewhere classified	0.000	0.997	0.003
M23.49 Loose body in knee-Unspec lig/men	0.000	0.997	0.003
M21.6 Other acquired deformities of ankle and foot	0.000	0.997	0.003
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.997	0.003
N94.1 Dyspareunia	0.003	0.997	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.997	0.003
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
M21.3 Wrist or foot drop (acquired)	0.000	0.997	0.003
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M21.2 Flexion deformity	0.000	0.997	0.003
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.997	0.003
M34.0 Progressive systemic sclerosis	0.000	0.997	0.003
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.997	0.003
K51.5 Mucosal proctocolitis	0.000	0.997	0.003
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.997	0.002
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.003	0.997	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.997	0.003
M21.4 Flat foot [pes planus] (acquired)	0.000	0.997	0.003
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.997	0.002
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
M31.6 Other giant cell arteritis	0.000	0.997	0.003
G04 Encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.997	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.997	0.002
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.002
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
N94.6 Dysmenorrhoea, unspecified	0.003	0.997	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.997	0.003
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.002
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.002
T40.2 Other opioids	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.000	0.998	0.002
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.998	0.002
M22.2 Patellofemoral disorders	0.000	0.998	0.002
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.998	0.002
M21.78 Unequal limb length (acquired)-Other	0.000	0.998	0.002
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.998	0.002
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.998	0.002
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.998	0.002
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.998	0.002
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.998	0.002
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.998	0.002
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.998	0.002
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.998	0.002
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.998	0.002
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.998	0.002
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.998	0.002
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.998	0.002
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.998	0.002
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.998	0.002
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.998	0.002
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.998	0.002
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.998	0.002
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.998	0.002
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.998	0.002
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.998	0.002
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.998	0.002
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.998	0.002
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.998	0.002
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.998	0.002
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.998	0.002
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.998	0.002
M34.9 Systemic sclerosis, unspecified	0.000	0.998	0.002
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.998	0.002
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.998	0.002
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.998	0.002
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.998	0.002
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.998	0.002
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.998	0.002
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.998	0.002
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.998	0.002
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.998	0.002
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
N94.3 Premenstrual tension syndrome	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
M24 Other specific joint derangements	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.998	0.002
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.998	0.002
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.998	0.002
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.998	0.002
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.998	0.002
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.998	0.002
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.998	0.002
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.998	0.002
Z88.2 Personal history of allergy to sulphonamides	0.000	0.998	0.002
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.998	0.002
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.998	0.002
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.998	0.002
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.998	0.002
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.998	0.002
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.998	0.002
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.998	0.002
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.998	0.002
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.998	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
M22.8 Other disorders of patella	0.000	0.998	0.002
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.998	0.002
N94.2 Vaginismus	0.002	0.998	0.000
N94.0 Mittelschmerz	0.002	0.998	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.998	0.002
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.998	0.002
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.998	0.002
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.998	0.002
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.998	0.002
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.998	0.002
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.998	0.002
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.998	0.002
R12 Heartburn	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.998	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.002	0.998	0.000
G04.1 Tropical spastic paraplegia	0.002	0.998	0.000
G04.0 Acute disseminated encephalitis	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.002	0.998	0.000
N94.5 Secondary dysmenorrhoea	0.002	0.998	0.000
N94.4 Primary dysmenorrhoea	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
H02.9 Disorder of eyelid, unspecified	0.000	0.998	0.002
L50.9 Urticaria, unspecified	0.000	0.998	0.002
M35 Other systemic involvement of connective tissue	0.000	0.998	0.002
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
M24.5 Contracture of joint	0.000	0.998	0.002
H93.8 Other specified disorders of ear	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
D39.1 Ovary	0.000	0.998	0.002
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.998	0.002
H92.1 Otorrhoea	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
C32.9 Larynx, unspecified	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.000	0.998	0.002
M24.6 Ankylosis of joint	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.998	0.002
M35.1 Other overlap syndromes	0.000	0.998	0.002
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.998	0.002
M24.0 Loose body in joint	0.000	0.998	0.002
E10.1 With ketoacidosis	0.000	0.998	0.002
M24.7 Protrusio acetabuli	0.000	0.998	0.002
E07 Other disorders of thyroid	0.000	0.998	0.002
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.998	0.002
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.998	0.002
M35.5 Multifocal fibrosclerosis	0.000	0.998	0.002
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.998	0.002
M35.2 Behcet's disease	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.000	0.998	0.002
M24.58 Contracture of joint (Other)	0.000	0.998	0.002
M24.57 Contracture of joint (Ankle and foot)	0.000	0.998	0.002
M24.56 Contracture of joint (Lower leg)	0.000	0.998	0.002
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.998	0.002
M24.53 Contracture of joint (Forearm)	0.000	0.998	0.002
M24.52 Contracture of joint (Upper arm)	0.000	0.998	0.002
M24.50 Contracture of joint (Multiple sites)	0.000	0.998	0.002
C09.9 Tonsil, unspecified	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
C06.9 Mouth, unspecified	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.998	0.001
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.002	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
W05.0 Home	0.002	0.998	0.000
G40.8 Other epilepsy	0.000	0.998	0.002
H92.0 Otalgia	0.002	0.998	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.998	0.002
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.998	0.001
M24.68 Ankylosis of joint (Other)	0.000	0.998	0.001
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.998	0.001
M24.66 Ankylosis of joint (Lower leg)	0.000	0.998	0.001
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.998	0.001
M24.64 Ankylosis of joint (Hand)	0.000	0.998	0.001
M24.63 Ankylosis of joint (Forearm)	0.000	0.998	0.001
M24.62 Ankylosis of joint (Upper arm)	0.000	0.998	0.001
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.998	0.001
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.998	0.001
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.998	0.001
M24.98 Joint derangement, unspecified (Other)	0.000	0.998	0.001
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.998	0.001
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.998	0.001
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M24.94 Joint derangement, unspecified (Hand)	0.000	0.998	0.001
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.998	0.001
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.998	0.001
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.998	0.001
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.998	0.001
H92.2 Otorrhagia	0.002	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.000	0.998	0.002
G06 Intracranial and intraspinal abscess and granuloma	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations