TreeWAS – Variant ID: rs1569175

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y83.4 Other reconstructive surgery	0.000	0.987	0.013
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.987	0.013
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.988	0.012
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.988	0.012
H71 Cholesteatoma of middle ear	0.000	0.990	0.010
H65-H75 Diseases of middle ear and mastoid	0.000	0.991	0.009
H74 Other disorders of middle ear and mastoid	0.000	0.991	0.008
Y83.5 Amputation of limb(s)	0.000	0.992	0.008
Y83.0 Surgical operation with transplant of whole organ	0.000	0.992	0.008
I63.9 Cerebral infarction, unspecified	0.008	0.992	0.000
H74.4 Polyp of middle ear	0.000	0.992	0.008
S42.00 Fracture of clavicle (closed)	0.000	0.992	0.008
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.992	0.008
H72 Perforation of tympanic membrane	0.000	0.992	0.008
Y83.8 Other surgical procedures	0.000	0.992	0.008
H73 Other disorders of tympanic membrane	0.000	0.993	0.007
H72.0 Central perforation of tympanic membrane	0.000	0.993	0.007
H73.8 Other specified disorders of tympanic membrane	0.000	0.993	0.007
H74.1 Adhesive middle ear disease	0.000	0.993	0.007
H70 Mastoiditis and related conditions	0.000	0.993	0.007
H69 Other disorders of Eustachian tube	0.000	0.993	0.007
H66 Suppurative and unspecified otitis media	0.000	0.993	0.007
H74.0 Tympanosclerosis	0.000	0.993	0.007
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.993	0.006
H68 Eustachian salpingitis and obstruction	0.000	0.993	0.006
H67 Otitis media in diseases classified elsewhere	0.000	0.993	0.006
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.994	0.006
M54.59 Low back pain (Site unspecified)	0.006	0.994	0.000
Y83.9 Surgical procedure, unspecified	0.000	0.994	0.006
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.994	0.006
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.994	0.006
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.994	0.006
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.994	0.006
H72.1 Attic perforation of tympanic membrane	0.000	0.994	0.006
G57.6 Lesion of plantar nerve	0.000	0.994	0.006
I63 Cerebral infarction	0.006	0.994	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.994	0.005
H73.0 Acute myringitis	0.000	0.994	0.005
H73.1 Chronic myringitis	0.000	0.994	0.005
I63.8 Other cerebral infarction	0.006	0.994	0.000
G57 Mononeuropathies of lower limb	0.000	0.994	0.006
H66.9 Otitis media, unspecified	0.000	0.994	0.005
H69.9 Eustachian tube disorder, unspecified	0.000	0.995	0.005
H72.2 Other marginal perforations of tympanic membrane	0.000	0.995	0.005
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.995	0.005
H70.8 Other mastoiditis and related conditions	0.000	0.995	0.005
H70.9 Mastoiditis, unspecified	0.000	0.995	0.005
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
G57.1 Meralgia paraesthetica	0.000	0.995	0.005
H66.0 Acute suppurative otitis media	0.000	0.995	0.005
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.995	0.005
M54.56 Low back pain (Lumbar region)	0.005	0.995	0.000
Y43.3 Other antineoplastic drugs	0.005	0.995	0.000
M54.5 Low back pain	0.005	0.995	0.000
C78.7 Secondary malignant neoplasm of liver	0.005	0.995	0.000
H70.2 Petrositis	0.000	0.995	0.005
H69.0 Patulous Eustachian tube	0.000	0.995	0.005
H66.4 Suppurative otitis media, unspecified	0.000	0.995	0.005
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.995	0.005
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.995	0.005
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.995	0.005
H68.1 Obstruction of Eustachian tube	0.000	0.995	0.005
H68.0 Eustachian salpingitis	0.000	0.995	0.005
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.995	0.005
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
H70.0 Acute mastoiditis	0.000	0.995	0.005
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.995	0.005
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.995	0.005
H70.1 Chronic mastoiditis	0.000	0.995	0.005
H69.8 Other specified disorders of Eustachian tube	0.000	0.995	0.005
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.005	0.995	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.995	0.005
G50-G59 Nerve, nerve root and plexus disorders	0.000	0.995	0.005
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.004	0.995	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.995	0.005
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.004	0.996	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.996	0.004
Y43 Primarily systemic agents	0.004	0.996	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.004	0.996	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.004	0.996	0.000
G57.3 Lesion of lateral popliteal nerve	0.000	0.996	0.004
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
G57.4 Lesion of medial popliteal nerve	0.000	0.996	0.004
G57.2 Lesion of femoral nerve	0.000	0.996	0.004
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.996	0.004
M54.50 Low back pain (Multiple sites in spine)	0.004	0.996	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.004	0.996	0.000
M54.54 Low back pain-Thoracic	0.004	0.996	0.000
C78.0 Secondary malignant neoplasm of lung	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.996	0.004
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
G51 Facial nerve disorders	0.000	0.996	0.004
R25.3 Fasciculation	0.000	0.996	0.004
G57.5 Tarsal tunnel syndrome	0.000	0.996	0.004
R25 Abnormal involuntary movements	0.000	0.996	0.004
M54.52 Low back pain-Cervical	0.004	0.996	0.000
G57.0 Lesion of sciatic nerve	0.000	0.996	0.004
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
C78.2 Secondary malignant neoplasm of pleura	0.004	0.996	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.004	0.996	0.000
G52 Disorders of other cranial nerves	0.000	0.996	0.004
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.996	0.004
M54.53 Low back pain-Cervicothoracic	0.004	0.996	0.000
M54.51 Low back pain-Occipit-atl-axl	0.004	0.996	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.004	0.996	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.004	0.996	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.004	0.996	0.000
K83.1 Obstruction of bile duct	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.000	0.996	0.004
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
G54 Nerve root and plexus disorders	0.000	0.996	0.004
G50 Disorders of trigeminal nerve	0.000	0.996	0.004
S42.0 Fracture of clavicle	0.000	0.996	0.004
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.004	0.996	0.000
G51.0 Bell's palsy	0.000	0.996	0.004
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
C78.4 Secondary malignant neoplasm of small intestine	0.004	0.996	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.000	0.996	0.004
C78.1 Secondary malignant neoplasm of mediastinum	0.004	0.996	0.000
M54.55 Low back pain (Thoracolumbar region)	0.004	0.996	0.000
Y40 Systemic antibiotics	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
M54.57 Low back pain (Lumbosacral region)	0.004	0.996	0.000
R27.0 Ataxia, unspecified	0.000	0.996	0.003
R79.8 Other specified abnormal findings of blood chemistry	0.004	0.996	0.000
Y43.2 Antineoplastic natural products	0.003	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.996	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.003
R27 Other lack of coordination	0.000	0.996	0.003
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
G51.8 Other disorders of facial nerve	0.000	0.997	0.003
R29.2 Abnormal reflex	0.000	0.997	0.003
G53 Cranial nerve disorders in diseases classified elsewhere	0.000	0.997	0.003
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
G52.9 Cranial nerve disorder, unspecified	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
G52.8 Disorders of other specified cranial nerves	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.997	0.003
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.997	0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.997	0.003
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.003	0.997	0.000
G52.1 Disorders of glossopharyngeal nerve	0.000	0.997	0.003
R29.4 Clicking hip	0.000	0.997	0.003
R29.3 Abnormal posture	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
G50.1 Atypical facial pain	0.000	0.997	0.003
G51.9 Disorder of facial nerve, unspecified	0.000	0.997	0.003
G51.4 Facial myokymia	0.000	0.997	0.003
G51.2 Melkersson's syndrome	0.000	0.997	0.003
G51.1 Geniculate ganglionitis	0.000	0.997	0.003
R26 Abnormalities of gait and mobility	0.000	0.997	0.003
G58 Other mononeuropathies	0.000	0.997	0.003
R25.0 Abnormal head movements	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.997	0.003
G50.0 Trigeminal neuralgia	0.000	0.997	0.003
G52.2 Disorders of vagus nerve	0.000	0.997	0.003
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
G54.6 Phantom limb syndrome with pain	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
G52.0 Disorders of olfactory nerve	0.000	0.997	0.003
G54.2 Cervical root disorders, not elsewhere classified	0.000	0.997	0.003
R29.0 Tetany	0.000	0.997	0.003
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.000	0.997	0.003
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
G52.3 Disorders of hypoglossal nerve	0.000	0.997	0.003
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.997	0.003
G50.9 Disorder of trigeminal nerve, unspecified	0.000	0.997	0.003
G52.7 Disorders of multiple cranial nerves	0.000	0.997	0.003
G54.4 Lumbosacral root disorders, not elsewhere classified	0.000	0.997	0.003
G54.8 Other nerve root and plexus disorders	0.000	0.997	0.003
R26.0 Ataxic gait	0.000	0.997	0.003
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
G54.7 Phantom limb syndrome without pain	0.000	0.997	0.003
G54.3 Thoracic root disorders, not elsewhere classified	0.000	0.997	0.003
G54.1 Lumbosacral plexus disorders	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.000	0.997	0.003
R29.1 Meningismus	0.000	0.997	0.003
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
G50.8 Other disorders of trigeminal nerve	0.000	0.997	0.003
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.003	0.997	0.000
S42.01 Fracture of clavicle (open)	0.000	0.997	0.003
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.003	0.997	0.000
G54.5 Neuralgic amyotrophy	0.000	0.997	0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
G51.3 Clonic hemifacial spasm	0.000	0.997	0.003
Y40.2 Chloramphenicol group	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
G54.0 Brachial plexus disorders	0.000	0.997	0.003
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
Y40.6 Rifamycins	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.003	0.997	0.000
M17.0 Primary gonarthrosis, bilateral	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.000	0.997	0.003
Y40.0 Penicillins	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
C79 Secondary malignant neoplasm of other sites	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
H81 Disorders of vestibular function	0.000	0.997	0.003
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.000	0.997	0.003
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.000	0.997	0.003
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.000	0.997	0.003
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
E78.5 Hyperlipidaemia, unspecified	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
G56 Mononeuropathies of upper limb	0.000	0.997	0.003
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
R25.2 Cramp and spasm	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y53.2 Stimulant laxatives	0.002	0.997	0.000
Y48.3 Local anaesthetics	0.002	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.997	0.000
Y53.4 Other laxatives	0.002	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.997	0.000
Y52.7 Peripheral vasodilators	0.002	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y53.7 Emetics	0.002	0.997	0.000
Y53.5 Digestants	0.002	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.997	0.000
Y59.0 Viral vaccines	0.002	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.997	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.997	0.000
Y59.3 Immunoglobulin	0.002	0.997	0.000
H90-H95 Other disorders of ear	0.000	0.997	0.003
C77.8 Lymph nodes of multiple regions	0.003	0.997	0.000
G58.7 Mononeuritis multiplex	0.000	0.997	0.002
R26.1 Paralytic gait	0.000	0.997	0.002
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.000	0.997	0.002
Y41.1 Antimycobacterial drugs	0.002	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.997	0.000
G53.0 Postzoster neuralgia	0.000	0.997	0.002
R25.1 Tremor, unspecified	0.000	0.997	0.002
Y45.1 Salicylates	0.002	0.997	0.000
Y57.8 Other drugs and medicaments	0.002	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.997	0.002
R26.3 Immobility	0.000	0.997	0.002
Y41.5 Antiviral drugs	0.002	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.997	0.000
C77.9 Lymph node, unspecified	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.997	0.003
Y56.9 Topical agent, unspecified	0.002	0.997	0.000
Y56.8 Other topical agents	0.002	0.997	0.000
Y56.7 Dental drugs, topically applied	0.002	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
Y56.2 Local astringents and local detergents	0.002	0.997	0.000
Y56.1 Antipruritics	0.002	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.997	0.003
G58.9 Mononeuropathy, unspecified	0.000	0.997	0.002
J34.2 Deviated nasal septum	0.000	0.997	0.003
R79 Other abnormal findings of blood chemistry	0.002	0.997	0.000
G58.0 Intercostal neuropathy	0.000	0.997	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
Y41.4 Anthelminthics	0.002	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.997	0.000
Y48.5 Therapeutic gases	0.002	0.997	0.000
Y48.1 Parenteral anaesthetics	0.002	0.997	0.000
Y48.0 Inhaled anaesthetics	0.002	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.998	0.002
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.998	0.002
G56.9 Mononeuropathy of upper limb, unspecified	0.000	0.998	0.002
Y41.0 Sulphonamides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
G58.8 Other specified mononeuropathies	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.000	0.998	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.002	0.998	0.000
G56.8 Other mononeuropathies of upper limb	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
R10.2 Pelvic and perineal pain	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.998	0.002
G56.3 Lesion of radial nerve	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
T82.3 Mechanical complication of other vascular grafts	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
R79.0 Abnormal level of blood mineral	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
H83 Other diseases of inner ear	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.000	0.998	0.002
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.002	0.998	0.000
G56.4 Causalgia	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
R79.9 Abnormal finding of blood chemistry, unspecified	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.002	0.998	0.000
G59.0 Diabetic mononeuropathy	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.000	0.998	0.002
H81.2 Vestibular neuronitis	0.000	0.998	0.002
H93.1 Tinnitus	0.000	0.998	0.002
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.998	0.002
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.000	0.998	0.002
Y45.4 Antirheumatics	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.001	0.998	0.002
N90.7 Vulvar cyst	0.002	0.998	0.000
N63 Unspecified lump in breast	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
G56.2 Lesion of ulnar nerve	0.000	0.998	0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.998	0.002
H80 Otosclerosis	0.000	0.998	0.002
H60-H62 Diseases of external ear	0.000	0.998	0.002
G56.1 Other lesions of median nerve	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.001	0.998	0.001
L40.9 Psoriasis, unspecified	0.002	0.998	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.998	0.002
H83.8 Other specified diseases of inner ear	0.000	0.998	0.002
H83.3 Noise effects on inner ear	0.000	0.998	0.002
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.002
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.998	0.002
H83.2 Labyrinthine dysfunction	0.000	0.998	0.002
C76.2 Abdomen	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.000	0.998	0.002
H93.0 Degenerative and vascular disorders of ear	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
K83 Other diseases of biliary tract	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.002	0.998	0.000
C76.7 Other ill-defined sites	0.002	0.998	0.000
C76.5 Lower limb	0.002	0.998	0.000
C76.4 Upper limb	0.002	0.998	0.000
C76.3 Pelvis	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.001	0.998	0.001
C90.0 Multiple myeloma	0.000	0.998	0.002
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
C76.1 Thorax	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.998	0.002
H81.0 Meniere's disease	0.000	0.998	0.002
H93.8 Other specified disorders of ear	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations