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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1571878
log Bayes Factor = 7.40574
Chromosome 6   position 167,540,842  (GRCh37) Explore rs1571878 on Ensembl!
Variant rs1571878 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.017 0.983
E00-E07 Disorders of thyroid gland
0.000 0.034 0.966
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.039 0.961
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.048 0.952
E03.8 Other specified hypothyroidism
0.000 0.108 0.892
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.149 0.850
E05.9 Thyrotoxicosis, unspecified
0.000 0.177 0.823
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.191 0.809
E07 Other disorders of thyroid
0.000 0.279 0.721
E03.1 Congenital hypothyroidism without goitre
0.000 0.295 0.705
E03.5 Myxoedema coma
0.000 0.295 0.704
E03.4 Atrophy of thyroid (acquired)
0.000 0.295 0.704
E03.3 Postinfectious hypothyroidism
0.000 0.295 0.704
E04 Other non-toxic goitre
0.000 0.305 0.695
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.307 0.692
E00 Congenital iodine-deficiency syndrome
0.000 0.307 0.692
E05.5 Thyroid crisis or storm
0.000 0.311 0.689
E05.4 Thyrotoxicosis factitia
0.000 0.311 0.689
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.311 0.689
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.311 0.689
E04.9 Non-toxic goitre, unspecified
0.000 0.369 0.631
E07.9 Disorder of thyroid, unspecified
0.000 0.391 0.609
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.417 0.583
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.458 0.542
E07.1 Dyshormogenetic goitre
0.000 0.483 0.517
E07.0 Hypersecretion of calcitonin
0.000 0.483 0.517
E04.0 Non-toxic diffuse goitre
0.000 0.483 0.517
E04.8 Other specified non-toxic goitre
0.000 0.501 0.499
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.503 0.496
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.503 0.496
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.503 0.496
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.503 0.496
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.503 0.496
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.503 0.496
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.503 0.496
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.503 0.496
E05.8 Other thyrotoxicosis
0.001 0.526 0.474
E04.2 Non-toxic multinodular goitre
0.000 0.565 0.435
E06 Thyroiditis
0.000 0.597 0.402
E07.8 Other specified disorders of thyroid
0.000 0.599 0.401
E14.9 Without complications
0.000 0.645 0.355
E14 Unspecified diabetes mellitus
0.000 0.646 0.354
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.655 0.345
E10-E14 Diabetes mellitus
0.000 0.660 0.340
E06.1 Subacute thyroiditis
0.000 0.680 0.320
E14.3 With ophthalmic complications
0.000 0.684 0.316
E14.1 With ketoacidosis
0.000 0.703 0.297
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.704 0.296
E06.4 Drug-induced thyroiditis
0.000 0.711 0.288
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.711 0.288
E06.0 Acute thyroiditis
0.000 0.711 0.288
E06.5 Other chronic thyroiditis
0.000 0.711 0.288
E13 Other specified diabetes mellitus
0.000 0.715 0.285
E14.5 With peripheral circulatory complications
0.000 0.731 0.269
E14.4 With neurological complications
0.000 0.733 0.267
E16 Other disorders of pancreatic internal secretion
0.000 0.739 0.261
E14.6 With other specified complications
0.000 0.739 0.261
E14.7 With multiple complications
0.000 0.746 0.254
E14.0 With coma
0.000 0.746 0.254
E13.9 Without complications
0.000 0.751 0.249
E14.2 Withrenal complications
0.000 0.753 0.247
E16.2 Hypoglycaemia, unspecified
0.000 0.755 0.245
E12 Malnutrition-related diabetes mellitus
0.000 0.756 0.244
E14.8 With unspecified complications
0.000 0.768 0.232
E40-E46 Malnutrition
0.000 0.768 0.232
E15 Nondiabetic hypoglycaemic coma
0.000 0.788 0.212
E04.1 Non-toxic single thyroid nodule
0.000 0.795 0.205
E13.8 With unspecified complications
0.000 0.796 0.204
E13.7 With multiple complications
0.000 0.796 0.204
E13.6 With other specified complications
0.000 0.796 0.204
E13.5 With peripheral circulatory complications
0.000 0.796 0.204
E13.4 With neurological complications
0.000 0.796 0.204
E13.2 With renal complications
0.000 0.796 0.204
E13.1 With ketoacidosis
0.000 0.796 0.204
E13.0 With coma
0.000 0.796 0.204
E13.3 With ophthalmic complications
0.000 0.804 0.196
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.812 0.187
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.812 0.187
E16.4 Abnormal secretion of gastrin
0.000 0.812 0.187
E16.3 Increased secretion of glucagon
0.000 0.812 0.187
E16.1 Other hypoglycaemia
0.000 0.813 0.187
E12.9 Without complications
0.000 0.825 0.175
E12.8 With unspecified complications
0.000 0.825 0.175
E12.7 With multiple complications
0.000 0.825 0.175
E12.6 With other specified complications
0.000 0.825 0.175
E12.5 With peripheral circulatory complications
0.000 0.825 0.175
E12.4 With neurological complications
0.000 0.825 0.175
E12.3 With ophthalmic complications
0.000 0.825 0.175
E12.2 With renal complications
0.000 0.825 0.175
E12.1 With ketoacidosis
0.000 0.825 0.175
E12.0 With coma
0.000 0.825 0.175
E50-E64 Other nutritional deficiencies
0.000 0.826 0.174
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.834 0.166
E45 Retarded development following protein-energy malnutrition
0.000 0.834 0.166
E43 Unspecified severe protein-energy malnutrition
0.000 0.834 0.166
E42 Marasmic kwashiorkor
0.000 0.834 0.166
E41 Nutritional marasmus
0.000 0.834 0.166
E40 Kwashiorkor
0.000 0.834 0.166
E06.9 Thyroiditis, unspecified
0.001 0.838 0.162
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.847 0.153
E46 Unspecified protein-energy malnutrition
0.000 0.849 0.151
E61 Deficiency of other nutrient elements
0.000 0.856 0.144
E58 Dietary calcium deficiency
0.000 0.860 0.140
E06.3 Autoimmune thyroiditis
0.000 0.861 0.139
E51 Thiamine deficiency
0.000 0.866 0.134
E61.1 Iron deficiency
0.000 0.871 0.129
E89.0 Postprocedural hypothyroidism
0.000 0.873 0.127
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.875 0.125
E50 Vitamin A deficiency
0.000 0.875 0.125
E60 Dietary zinc deficiency
0.000 0.875 0.125
E59 Dietary selenium deficiency
0.000 0.875 0.125
E52 Niacin deficiency [pellagra]
0.000 0.875 0.125
K55.2 Angiodysplasia of colon
0.122 0.878 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.880 0.119
E44.0 Moderate protein-energy malnutrition
0.000 0.880 0.119
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.881 0.119
E63 Other nutritional deficiencies
0.000 0.883 0.116
E56 Other vitamin deficiencies
0.000 0.885 0.115
E70-E90 Metabolic disorders
0.000 0.887 0.113
E65-E68 Obesity and other hyperalimentation
0.000 0.892 0.108
E54 Ascorbic acid deficiency
0.000 0.892 0.108
E51.2 Wernicke's encephalopathy
0.000 0.895 0.105
K55 Vascular disorders of intestine
0.105 0.895 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.897 0.103
E61.8 Deficiency of other specified nutrient elements
0.000 0.897 0.103
E61.7 Deficiency of multiple nutrient elements
0.000 0.897 0.103
E61.6 Vanadium deficiency
0.000 0.897 0.103
E61.5 Molybdenum deficiency
0.000 0.897 0.103
E61.4 Chromium deficiency
0.000 0.897 0.103
E61.3 Manganese deficiency
0.000 0.897 0.103
E61.0 Copper deficiency
0.000 0.897 0.103
E89.2 Postprocedural hypoparathyroidism
0.000 0.899 0.101
K55.9 Vascular disorder of intestine, unspecified
0.097 0.903 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.904 0.096
E51.8 Other manifestations of thiamine deficiency
0.000 0.904 0.096
E51.1 Beriberi
0.000 0.904 0.096
K55.0 Acute vascular disorders of intestine
0.094 0.906 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.910 0.089
E50.8 Other manifestations of vitamin A deficiency
0.000 0.910 0.089
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.910 0.089
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.910 0.089
E50.5 Vitamin A deficiency with night blindness
0.000 0.910 0.089
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.910 0.089
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.910 0.089
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.910 0.089
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.910 0.089
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.910 0.089
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.910 0.089
E64.8 Sequelae of other nutritional deficiencies
0.000 0.910 0.089
E64.3 Sequelae of rickets
0.000 0.910 0.089
E64.2 Sequelae of vitamin C deficiency
0.000 0.910 0.089
E64.1 Sequelae of vitamin A deficiency
0.000 0.910 0.089
E64.0 Sequelae of protein-energy malnutrition
0.000 0.910 0.089
E89.5 Postprocedural testicular hypofunction
0.000 0.913 0.087
E61.2 Magnesium deficiency
0.000 0.914 0.086
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.915 0.085
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.915 0.085
E89.1 Postprocedural hypoinsulinaemia
0.000 0.915 0.085
E63.8 Other specified nutritional deficiencies
0.000 0.916 0.084
E63.1 Imbalance of constituents of food intake
0.000 0.916 0.084
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.916 0.084
E79 Disorders of purine and pyrimidine metabolism
0.000 0.917 0.083
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.917 0.083
E56.9 Vitamin deficiency, unspecified
0.000 0.917 0.082
E56.8 Deficiency of other vitamins
0.000 0.917 0.082
E56.0 Deficiency of vitamin E
0.000 0.917 0.082
E84 Cystic fibrosis
0.000 0.918 0.081
E76 Disorders of glycosaminoglycan metabolism
0.000 0.919 0.081
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.919 0.081
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.919 0.081
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.919 0.081
E72 Other disorders of amino-acid metabolism
0.000 0.919 0.080
E53 Deficiency of other B group vitamins
0.000 0.920 0.080
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.920 0.079
E70 Disorders of aromatic amino-acid metabolism
0.000 0.921 0.079
E67 Other hyperalimentation
0.000 0.922 0.078
E68 Sequelae of hyperalimentation
0.000 0.922 0.078
E77 Disorders of glycoprotein metabolism
0.000 0.922 0.078
E55 Vitamin D deficiency
0.001 0.923 0.077
E89.4 Postprocedural ovarian failure
0.000 0.924 0.076
E89.3 Postprocedural hypopituitarism
0.000 0.924 0.076
E63.9 Nutritional deficiency, unspecified
0.000 0.924 0.075
E74 Other disorders of carbohydrate metabolism
0.000 0.925 0.075
K55.1 Chronic vascular disorders of intestine
0.075 0.925 0.000
E85 Amyloidosis
0.000 0.927 0.073
E80.2 Other porphyria
0.000 0.927 0.073
E56.1 Deficiency of vitamin K
0.000 0.927 0.072
K55.8 Other vascular disorders of intestine
0.071 0.929 0.000
E83 Disorders of mineral metabolism
0.000 0.930 0.070
E10 Insulin-dependent diabetes mellitus
0.000 0.932 0.068
E80.6 Other disorders of bilirubin metabolism
0.000 0.937 0.063
E10.9 Without complications
0.000 0.937 0.063
E72.0 Disorders of amino-acid transport
0.000 0.938 0.062
E80.5 Crigler-Najjar syndrome
0.000 0.939 0.061
E80.3 Defects of catalase and peroxydase
0.000 0.939 0.061
E80.0 Hereditary erythropoietic porphyria
0.000 0.939 0.061
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.939 0.061
E75.5 Other lipid storage disorders
0.000 0.940 0.060
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.940 0.060
E73 Lactose intolerance
0.000 0.940 0.060
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.940 0.059
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.940 0.059
E79.1 Lesch-Nyhan syndrome
0.000 0.940 0.059
E84.8 Cystic fibrosis with other manifestations
0.000 0.941 0.059
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.941 0.059
E71.3 Disorders of fatty-acid metabolism
0.000 0.941 0.058
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.941 0.058
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.941 0.058
E71.0 Maple-syrup-urine disease
0.000 0.941 0.058
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.941 0.058
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.941 0.058
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.941 0.058
E76.2 Other mucopolysaccharidoses
0.000 0.941 0.058
E76.1 Mucopolysaccharidosis, type II
0.000 0.941 0.058
E76.0 Mucopolysaccharidosis, type I
0.000 0.941 0.058
E85.4 Organ-limited amyloidosis
0.000 0.941 0.058
E80.4 Gilbert's syndrome
0.000 0.942 0.058
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.942 0.058
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.942 0.058
E72.5 Disorders of glycine metabolism
0.000 0.942 0.058
E72.4 Disorders of ornithine metabolism
0.000 0.942 0.058
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.942 0.058
E72.2 Disorders of urea cycle metabolism
0.000 0.942 0.058
E88 Other metabolic disorders
0.000 0.943 0.057
E53.1 Pyridoxine deficiency
0.000 0.943 0.057
E53.0 Riboflavin deficiency
0.000 0.943 0.057
E84.9 Cystic fibrosis, unspecified
0.000 0.943 0.057
E75.6 Lipid storage disorder, unspecified
0.000 0.943 0.057
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.943 0.057
E75.3 Sphingolipidosis, unspecified
0.000 0.943 0.057
E75.1 Other gangliosidosis
0.000 0.943 0.057
E75.0 GM2 gangliosidosis
0.000 0.943 0.057
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.943 0.057
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.943 0.057
E70.2 Disorders of tyrosine metabolism
0.000 0.943 0.057
E70.1 Other hyperphenylalaninaemias
0.000 0.943 0.057
E70.0 Classical phenylketonuria
0.000 0.943 0.057
E80.1 Porphyria cutanea tarda
0.000 0.943 0.057
E67.8 Other specified hyperalimentation
0.000 0.944 0.056
E67.3 Hypervitaminosis D
0.000 0.944 0.056
E67.2 Megavitamin-B6 syndrome
0.000 0.944 0.056
E67.1 Hypercarotenaemia
0.000 0.944 0.056
E67.0 Hypervitaminosis A
0.000 0.944 0.056
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.944 0.056
E77.1 Defects in glycoprotein degradation
0.000 0.944 0.056
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.944 0.056
E55.0 Rickets, active
0.001 0.944 0.055
E70.3 Albinism
0.000 0.945 0.054
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.946 0.054
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.946 0.054
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.946 0.054
E74.2 Disorders of galactose metabolism
0.000 0.946 0.054
E74.1 Disorders of fructose metabolism
0.000 0.946 0.054
E53.9 Vitamin B deficiency, unspecified
0.000 0.946 0.054
E74.0 Glycogen storage disease
0.000 0.946 0.054
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.947 0.053
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.947 0.053
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.947 0.053
E85.8 Other amyloidosis
0.000 0.947 0.052
E83.1 Disorders of iron metabolism
0.000 0.947 0.053
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.947 0.052
E77.8 Other disorders of glycoprotein metabolism
0.000 0.948 0.052
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.948 0.052
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.948 0.052
E75.2 Other sphingolipidosis
0.000 0.948 0.052
E83.5 Disorders of calcium metabolism
0.000 0.948 0.052
E10.7 With multiple complications
0.000 0.949 0.051
E83.8 Other disorders of mineral metabolism
0.000 0.950 0.050
E83.2 Disorders of zinc metabolism
0.000 0.950 0.050
E83.0 Disorders of copper metabolism
0.000 0.950 0.050
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.952 0.048
E10.1 With ketoacidosis
0.000 0.952 0.048
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.953 0.046
E85.3 Secondary systemic amyloidosis
0.000 0.954 0.046
E88.8 Other specified metabolic disorders
0.000 0.954 0.045
E10.0 With coma
0.000 0.954 0.045
E85.9 Amyloidosis, unspecified
0.000 0.957 0.043
E88.9 Metabolic disorder, unspecified
0.000 0.957 0.043
E73.8 Other lactose intolerance
0.000 0.957 0.043
E73.1 Secondary lactase deficiency
0.000 0.957 0.043
E73.0 Congenital lactase deficiency
0.000 0.957 0.043
E10.2 With renal complications
0.000 0.958 0.042
E83.3 Disorders of phosphorus metabolism
0.000 0.958 0.042
E65 Localised adiposity
0.000 0.958 0.041
E83.4 Disorders of magnesium metabolism
0.000 0.959 0.041
E10.6 With other specified complications
0.000 0.959 0.041
E10.8 With unspecified complications
0.000 0.962 0.038
E10.4 With neurological complications
0.000 0.963 0.037
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.966 0.034
E88.2 Lipomatosis, not elsewhere classified
0.000 0.969 0.031
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.970 0.030
E66 Obesity
0.000 0.970 0.030
M06.9 Rheumatoid arthritis, unspecified
0.000 0.970 0.030
E78.1 Pure hyperglyceridaemia
0.000 0.971 0.029
E78.4 Other hyperlipidaemia
0.000 0.971 0.029
E88.3 Tumour lysis syndrome
0.000 0.972 0.028
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.972 0.027
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.973 0.027
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.974 0.026
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.974 0.026
M06.34 Rheumatoid nodule (Hand)
0.000 0.975 0.025
E78.6 Lipoprotein deficiency
0.000 0.975 0.025
E78.3 Hyperchylomicronaemia
0.000 0.975 0.025
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.975 0.025
E20-E35 Disorders of other endocrine glands
0.000 0.975 0.025
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.976 0.024
E66.0 Obesity due to excess calories
0.000 0.976 0.024
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.976 0.024
M06.3 Rheumatoid nodule
0.000 0.976 0.024
M06 Other rheumatoid arthritis
0.000 0.977 0.023
E78.2 Mixed hyperlipidaemia
0.000 0.977 0.023
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.978 0.022
E66.1 Drug-induced obesity
0.000 0.978 0.022
E73.9 Lactose intolerance, unspecified
0.001 0.978 0.021
E10.5 With peripheral circulatory complications
0.000 0.978 0.021
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.978 0.022
E78.8 Other disorders of lipoprotein metabolism
0.000 0.978 0.022
E53.8 Deficiency of other specified B group vitamins
0.000 0.980 0.020
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.980 0.020
E10.3 With ophthalmic complications
0.000 0.980 0.020
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.980 0.020
E24 Cushing's syndrome
0.000 0.980 0.020
M06.8 Other specified rheumatoid arthritis
0.000 0.981 0.019
C43.5 Malignant melanoma of trunk
0.019 0.981 0.000
E26 Hyperaldosteronism
0.000 0.981 0.019
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.982 0.018
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.982 0.018
E32 Diseases of thymus
0.000 0.982 0.018
E30 Disorders of puberty, not elsewhere classified
0.000 0.982 0.018
E29 Testicular dysfunction
0.000 0.982 0.018
E25 Adrenogenital disorders
0.000 0.982 0.017
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.983 0.017
E24.9 Cushing's syndrome, unspecified
0.000 0.983 0.017
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.983 0.017
M06.38 Rheumatoid nodule (Other)
0.000 0.983 0.017
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.983 0.017
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.983 0.017
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.983 0.017
M06.33 Rheumatoid nodule (Forearm)
0.000 0.983 0.017
E31 Polyglandular dysfunction
0.000 0.983 0.017
M06.2 Rheumatoid bursitis
0.000 0.983 0.017
M06.1 Adult-onset Still's disease
0.000 0.983 0.017
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.984 0.016
E28 Ovarian dysfunction
0.000 0.984 0.016
E20 Hypoparathyroidism
0.000 0.984 0.016
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.985 0.015
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.985 0.015
E24.0 Pituitary-dependent Cushing's disease
0.000 0.985 0.015
E26.9 Hyperaldosteronism, unspecified
0.000 0.985 0.015
M06.4 Inflammatory polyarthropathy
0.000 0.985 0.014
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.985 0.014
E24.3 Ectopic ACTH syndrome
0.000 0.985 0.014
E24.1 Nelson's syndrome
0.000 0.985 0.014
E24.2 Drug-induced Cushing's syndrome
0.000 0.986 0.014
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.986 0.014
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.986 0.014
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.986 0.014
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.986 0.014
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.986 0.014
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.986 0.014
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.986 0.014
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.986 0.014
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.986 0.014
E26.8 Other hyperaldosteronism
0.000 0.986 0.014
E26.1 Secondary hyperaldosteronism
0.000 0.986 0.014
E26.0 Primary hyperaldosteronism
0.000 0.987 0.013
E30.9 Disorder of puberty, unspecified
0.000 0.987 0.013
E30.8 Other disorders of puberty
0.000 0.987 0.013
E30.1 Precocious puberty
0.000 0.987 0.013
E30.0 Delayed puberty
0.000 0.987 0.013
E32.9 Disease of thymus, unspecified
0.000 0.987 0.013
E32.8 Other diseases of thymus
0.000 0.987 0.013
E32.1 Abscess of thymus
0.000 0.987 0.013
E32.0 Persistent hyperplasia of thymus
0.000 0.987 0.013
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.987 0.013
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.987 0.013
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.987 0.013
E29.1 Testicular hypofunction
0.000 0.987 0.013
E29.8 Other testicular dysfunction
0.000 0.987 0.013
E29.0 Testicular hyperfunction
0.000 0.987 0.013
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.987 0.013
E29.9 Testicular dysfunction, unspecified
0.000 0.987 0.013
E25.9 Adrenogenital disorder, unspecified
0.000 0.987 0.013
E25.8 Other adrenogenital disorders
0.000 0.987 0.013
E27 Other disorders of adrenal gland
0.000 0.987 0.013
E24.8 Other Cushing's syndrome
0.000 0.987 0.012
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.988 0.012
E31.9 Polyglandular dysfunction, unspecified
0.000 0.988 0.012
E31.8 Other polyglandular dysfunction
0.000 0.988 0.012
E31.1 Polyglandular hyperfunction
0.000 0.988 0.012
E28.3 Primary ovarian failure
0.000 0.988 0.012
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.988 0.012
M06.18 Adult-onset Still's disease (Other)
0.000 0.988 0.012
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.988 0.012
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.988 0.012
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.988 0.012
M06.14 Adult-onset Still's disease (Hand)
0.000 0.988 0.012
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.988 0.012
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.988 0.012
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.988 0.012
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.988 0.012
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.988 0.012
M06.28 Rheumatoid bursitis (Other)
0.000 0.988 0.012
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.988 0.012
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.988 0.012
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.988 0.012
M06.24 Rheumatoid bursitis (Hand)
0.000 0.988 0.012
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.988 0.012
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.988 0.012
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.988 0.012
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.988 0.012
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.988 0.012
E21.2 Other hyperparathyroidism
0.000 0.988 0.012
E28.9 Ovarian dysfunction, unspecified
0.000 0.988 0.011
E28.8 Other ovarian dysfunction
0.000 0.988 0.011
E28.1 Androgen excess
0.000 0.988 0.011
E28.0 Oestrogen excess
0.000 0.988 0.011
E20.8 Other hypoparathyroidism
0.000 0.988 0.011
E20.1 Pseudohypoparathyroidism
0.000 0.988 0.011
E20.0 Idiopathic hypoparathyroidism
0.000 0.988 0.011
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.989 0.011
E31.0 Autoimmune polyglandular failure
0.000 0.989 0.011
E23 Hypofunction and other disorders of pituitary gland
0.000 0.989 0.011
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.989 0.011
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.989 0.011
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.989 0.011
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.989 0.011
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.989 0.011
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.989 0.011
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.989 0.011
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.989 0.011
E34 Other endocrine disorders
0.000 0.989 0.010
E21.4 Other specified disorders of parathyroid gland
0.000 0.990 0.010
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.990 0.010
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.991 0.009
M79.67 Pain in limb (Ankle and foot)
0.000 0.991 0.009
E27.5 Adrenomedullary hyperfunction
0.000 0.991 0.009
E27.0 Other adrenocortical overactivity
0.000 0.991 0.009
E20.9 Hypoparathyroidism, unspecified
0.000 0.991 0.009
E23.7 Disorder of pituitary gland, unspecified
0.000 0.991 0.009
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.991 0.009
E21.0 Primary hyperparathyroidism
0.000 0.991 0.009
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.991 0.009
D43.2 Brain, unspecified
0.009 0.991 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.992 0.008
E55.9 Vitamin D deficiency, unspecified
0.001 0.992 0.007
E23.1 Drug-induced hypopituitarism
0.000 0.992 0.008
E27.2 Addisonian crisis
0.000 0.992 0.008
E22 Hyperfunction of pituitary gland
0.000 0.992 0.008
E66.8 Other obesity
0.000 0.992 0.008
E23.0 Hypopituitarism
0.000 0.992 0.008
E27.1 Primary adrenocortical insufficiency
0.000 0.992 0.008
E28.2 Polycystic ovarian syndrome
0.000 0.992 0.008
E34.5 Androgen resistance syndrome
0.000 0.992 0.007
E34.4 Constitutional tall stature
0.000 0.992 0.007
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.992 0.007
E34.1 Other hypersecretion of intestinal hormones
0.000 0.992 0.007
K70.3 Alcoholic cirrhosis of liver
0.008 0.992 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.993 0.007
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.993 0.007
E27.8 Other specified disorders of adrenal gland
0.000 0.993 0.007
E34.3 Short stature, not elsewhere classified
0.001 0.993 0.006
E27.9 Disorder of adrenal gland, unspecified
0.000 0.993 0.006
D46.9 Myelodysplastic syndrome, unspecified
0.007 0.993 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.007 0.993 0.000
H10.9 Conjunctivitis, unspecified
0.007 0.993 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.994 0.006
D46 Myelodysplastic syndromes
0.006 0.994 0.000
E34.8 Other specified endocrine disorders
0.001 0.994 0.005
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.994 0.006
E23.2 Diabetes insipidus
0.000 0.994 0.006
E23.6 Other disorders of pituitary gland
0.000 0.994 0.006
Q27.3 Peripheral arteriovenous malformation
0.006 0.994 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.994 0.005
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.994 0.005
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.994 0.005
E22.0 Acromegaly and pituitary gigantism
0.000 0.994 0.005
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.994 0.005
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.994 0.005
D43.1 Brain, infratentorial
0.005 0.994 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.995 0.005
D46.4 Refractory anaemia, unspecified
0.005 0.995 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.995 0.005
J35.0 Chronic tonsillitis
0.000 0.995 0.005
D37-D48 Neoplasms of uncertain or unknown behaviour
0.005 0.995 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.995 0.005
D43.9 Central nervous system, unspecified
0.005 0.995 0.000
D43.7 Other parts of central nervous system
0.005 0.995 0.000
D43.3 Cranial nerves
0.005 0.995 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.995 0.005
D46.5 Refractory anaemia with multi-lineage dysplasia
0.005 0.995 0.000
C44.3 Skin of other and unspecified parts of face
0.005 0.995 0.000
D43.4 Spinal cord
0.005 0.995 0.000
D46.7 Other myelodysplastic syndromes
0.005 0.995 0.000
E34.0 Carcinoid syndrome
0.001 0.995 0.004
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.005 0.995 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.005 0.995 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.005 0.995 0.000
E22.1 Hyperprolactinaemia
0.000 0.995 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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