TreeWAS – Variant ID: rs157580

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.000	1.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.000	1.000
F03 Unspecified dementia	0.000	0.000	1.000
G30.9 Alzheimer's disease, unspecified	0.000	0.000	1.000
F00 Dementia in Alzheimer's disease	0.000	0.000	1.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.002	0.998
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.004	0.996
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.012	0.988
F01 Vascular dementia	0.000	0.039	0.961
I25.2 Old myocardial infarction	0.000	0.050	0.950
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.053	0.947
I25.3 Aneurysm of heart	0.000	0.063	0.937
F02 Dementia in other diseases classified elsewhere	0.000	0.065	0.935
F01.9 Vascular dementia, unspecified	0.000	0.066	0.934
I20-I25 Ischaemic heart diseases	0.000	0.066	0.934
G30 Alzheimer's disease	0.000	0.071	0.929
E78.4 Other hyperlipidaemia	0.000	0.079	0.921
F05.9 Delirium, unspecified	0.000	0.086	0.914
I20 Angina pectoris	0.000	0.096	0.904
E78.2 Mixed hyperlipidaemia	0.000	0.103	0.897
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.111	0.889
I20.9 Angina pectoris, unspecified	0.000	0.123	0.877
F05.1 Delirium superimposed on dementia	0.000	0.130	0.870
I22 Subsequent myocardial infarction	0.000	0.135	0.865
I20.0 Unstable angina	0.000	0.150	0.850
F05.0 Delirium not superimposed on dementia, so described	0.000	0.153	0.847
F05.8 Other delirium	0.000	0.167	0.833
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.173	0.827
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.181	0.819
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.191	0.809
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.192	0.808
I25.5 Ischaemic cardiomyopathy	0.000	0.192	0.808
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.199	0.801
F02.3 Dementia in Parkinson's disease	0.000	0.200	0.800
R41.0 Disorientation, unspecified	0.000	0.219	0.781
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.223	0.777
G30.0 Alzheimer's disease with early onset	0.000	0.224	0.776
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.226	0.774
G30-G32 Other degenerative diseases of the nervous system	0.000	0.228	0.772
F02.0 Dementia in Pick's disease	0.000	0.257	0.743
G30.8 Other Alzheimer's disease	0.000	0.258	0.742
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.265	0.735
G30.1 Alzheimer's disease with late onset	0.000	0.277	0.723
F09 Unspecified organic or symptomatic mental disorder	0.000	0.283	0.717
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.283	0.717
E78.3 Hyperchylomicronaemia	0.000	0.283	0.717
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.283	0.717
G31.8 Other specified degenerative diseases of nervous system	0.000	0.284	0.716
I22.8 Subsequent myocardial infarction of other sites	0.000	0.289	0.711
E78.8 Other disorders of lipoprotein metabolism	0.000	0.291	0.709
F01.1 Multi-infarct dementia	0.000	0.310	0.690
F01.8 Other vascular dementia	0.000	0.311	0.689
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.311	0.689
F01.2 Subcortical vascular dementia	0.000	0.311	0.689
F01.0 Vascular dementia of acute onset	0.000	0.311	0.689
I23 Certain current complications following acute myocardial infarction	0.000	0.315	0.685
I21 Acute myocardial infarction	0.000	0.324	0.676
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.325	0.675
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.330	0.670
F02.2 Dementia in Huntington's disease	0.000	0.330	0.670
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.330	0.670
I25.6 Silent myocardial ischaemia	0.000	0.333	0.667
Z95.1 Presence of aortocoronary bypass graft	0.000	0.335	0.665
I21.9 Acute myocardial infarction, unspecified	0.000	0.359	0.641
Z95.0 Presence of cardiac pacemaker	0.000	0.360	0.640
E78.6 Lipoprotein deficiency	0.000	0.363	0.636
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.365	0.635
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.368	0.632
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.372	0.628
E78.1 Pure hyperglyceridaemia	0.000	0.394	0.605
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.400	0.600
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.412	0.588
G31.0 Circumscribed brain atrophy	0.000	0.438	0.562
R41.2 Retrograde amnesia	0.000	0.452	0.548
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.453	0.547
R41.3 Other amnesia	0.000	0.459	0.541
I20.8 Other forms of angina pectoris	0.000	0.462	0.538
F06.7 Mild cognitive disorder	0.000	0.463	0.537
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.473	0.527
I23.8 Other current complications following acute myocardial infarction	0.000	0.493	0.507
G31.2 Degeneration of nervous system due to alcohol	0.000	0.497	0.503
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.504	0.496
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.509	0.491
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.509	0.491
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.509	0.491
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.509	0.491
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.509	0.491
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.509	0.491
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.509	0.491
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.515	0.485
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.516	0.484
F06.5 Organic dissociative disorder	0.000	0.516	0.484
F06.4 Organic anxiety disorder	0.000	0.516	0.484
F06.3 Organic mood [affective] disorders	0.000	0.516	0.484
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.516	0.484
F06.1 Organic catatonic disorder	0.000	0.516	0.484
F06.0 Organic hallucinosis	0.000	0.516	0.484
I25.4 Coronary artery aneurysm	0.000	0.518	0.482
F07.2 Postconcussional syndrome	0.000	0.538	0.462
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.544	0.456
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.545	0.455
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.545	0.455
F07.1 Postencephalitic syndrome	0.000	0.545	0.455
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.547	0.453
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.553	0.447
Z95.3 Presence of xenogenic heart valve	0.000	0.558	0.442
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.576	0.424
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.578	0.422
Z95.4 Presence of other heart-valve replacement	0.000	0.583	0.417
R41.1 Anterograde amnesia	0.000	0.590	0.409
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.591	0.409
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.593	0.406
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.603	0.397
F07.0 Organic personality disorder	0.001	0.637	0.363
R44.3 Hallucinations, unspecified	0.000	0.639	0.361
R45 Symptoms and signs involving emotional state	0.000	0.652	0.348
R44.0 Auditory hallucinations	0.000	0.653	0.347
R46 Symptoms and signs involving appearance and behaviour	0.000	0.658	0.342
R44.1 Visual hallucinations	0.000	0.659	0.341
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.660	0.340
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.664	0.336
R45.1 Restlessness and agitation	0.000	0.669	0.331
I24 Other acute ischaemic heart diseases	0.000	0.672	0.328
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.691	0.308
I21.4 Acute subendocardial myocardial infarction	0.000	0.700	0.300
R44.2 Other hallucinations	0.000	0.705	0.295
R45.7 State of emotional shock and stress, unspecified	0.000	0.718	0.282
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.731	0.269
R46.2 Strange and inexplicable behaviour	0.000	0.734	0.266
R46.0 Very low level of personal hygiene	0.000	0.740	0.260
I24.1 Dressler's syndrome	0.000	0.741	0.259
R45.0 Nervousness	0.000	0.743	0.256
R45.5 Hostility	0.000	0.744	0.256
R45.6 Physical violence	0.000	0.745	0.255
R45.3 Demoralisation and apathy	0.000	0.751	0.249
R46.4 Slowness and poor responsiveness	0.000	0.754	0.246
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.755	0.245
R46.6 Undue concern and preoccupation with stressful events	0.000	0.755	0.245
R46.5 Suspiciousness and marked evasiveness	0.000	0.755	0.245
R46.3 Overactivity	0.000	0.755	0.245
R46.1 Bizarre personal appearance	0.000	0.755	0.245
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.759	0.241
I50 Heart failure	0.000	0.769	0.231
I50.0 Congestive heart failure	0.000	0.775	0.225
I20.1 Angina pectoris with documented spasm	0.001	0.778	0.221
I50.9 Heart failure, unspecified	0.000	0.780	0.220
I50.1 Left ventricular failure	0.000	0.781	0.219
I49 Other cardiac arrhythmias	0.000	0.793	0.207
I49.3 Ventricular premature depolarisation	0.000	0.795	0.205
I49.8 Other specified cardiac arrhythmias	0.000	0.795	0.205
I30-I52 Other forms of heart disease	0.000	0.795	0.205
I51 Complications and ill-defined descriptions of heart disease	0.000	0.797	0.203
R45.4 Irritability and anger	0.000	0.806	0.194
I51.6 Cardiovascular disease, unspecified	0.000	0.806	0.194
I46 Cardiac arrest	0.000	0.808	0.192
R43 Disturbances of smell and taste	0.000	0.813	0.187
I51.7 Cardiomegaly	0.000	0.816	0.184
R45.2 Unhappiness	0.000	0.821	0.179
I51.4 Myocarditis, unspecified	0.000	0.822	0.178
I33 Acute and subacute endocarditis	0.000	0.824	0.176
I46.0 Cardiac arrest with successful resuscitation	0.000	0.825	0.175
R45.8 Other symptoms and signs involving emotional state	0.000	0.828	0.172
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.833	0.167
Chapter IX Diseases of the circulatory system	0.000	0.836	0.164
I24.8 Other forms of acute ischaemic heart disease	0.000	0.837	0.163
I51.0 Cardiac septal defect, acquired	0.000	0.837	0.162
I46.9 Cardiac arrest, unspecified	0.000	0.839	0.161
I33.0 Acute and subacute infective endocarditis	0.000	0.844	0.156
I40 Acute myocarditis	0.000	0.846	0.154
I37 Pulmonary valve disorders	0.000	0.849	0.151
I49.1 Atrial premature depolarisation	0.000	0.849	0.151
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.850	0.150
I49.2 Junctional premature depolarisation	0.000	0.851	0.148
I31 Other diseases of pericardium	0.000	0.852	0.148
I52 Other heart disorders in diseases classified elsewhere	0.000	0.853	0.147
I48 Atrial fibrillation and flutter	0.000	0.853	0.147
I41 Myocarditis in diseases classified elsewhere	0.000	0.853	0.147
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.853	0.147
I32 Pericarditis in diseases classified elsewhere	0.000	0.853	0.147
I36 Nonrheumatic tricuspid valve disorders	0.000	0.853	0.147
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.854	0.146
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.855	0.145
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.858	0.142
I51.5 Myocardial degeneration	0.000	0.858	0.141
I49.0 Ventricular fibrillation and flutter	0.000	0.858	0.142
I46.1 Sudden cardiac death, so described	0.000	0.862	0.138
R43.2 Parageusia	0.000	0.866	0.134
I33.9 Acute endocarditis, unspecified	0.000	0.875	0.125
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.875	0.125
I51.8 Other ill-defined heart diseases	0.000	0.876	0.124
I31.1 Chronic constrictive pericarditis	0.000	0.879	0.121
I31.9 Disease of pericardium, unspecified	0.000	0.879	0.121
I49.4 Other and unspecified premature depolarisation	0.000	0.880	0.120
I38 Endocarditis, valve unspecified	0.000	0.880	0.120
I40.9 Acute myocarditis, unspecified	0.000	0.880	0.119
I51.9 Heart disease, unspecified	0.000	0.881	0.119
R43.8 Other and unspecified disturbances of smell and taste	0.000	0.882	0.118
R43.1 Parosmia	0.001	0.883	0.117
I37.1 Pulmonary valve insufficiency	0.000	0.883	0.117
I00-I02 Acute rheumatic fever	0.000	0.885	0.115
I40.8 Other acute myocarditis	0.000	0.889	0.111
I40.1 Isolated myocarditis	0.000	0.889	0.111
I40.0 Infective myocarditis	0.000	0.891	0.109
I37.9 Pulmonary valve disorder, unspecified	0.000	0.891	0.108
I37.8 Other pulmonary valve disorders	0.000	0.891	0.108
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.891	0.108
I49.5 Sick sinus syndrome	0.000	0.892	0.108
I31.8 Other specified diseases of pericardium	0.000	0.894	0.106
I31.2 Haemopericardium, not elsewhere classified	0.000	0.894	0.106
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.894	0.106
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.894	0.106
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.894	0.106
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.894	0.106
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.894	0.106
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.894	0.106
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.894	0.106
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.894	0.106
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.894	0.106
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.894	0.106
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.894	0.106
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.894	0.106
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.894	0.106
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.894	0.106
I48.4 Atypical atrial flutter	0.000	0.894	0.106
I48.3 Typical atrial flutter	0.000	0.894	0.106
I48.2 Chronic atrial fibrillation	0.000	0.894	0.106
I48.1 Persistent atrial fibrillation	0.000	0.894	0.106
I48.0 Paroxysmal atrial fibrillation	0.000	0.894	0.106
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.894	0.106
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.894	0.106
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.894	0.106
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.894	0.105
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.894	0.105
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.894	0.105
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.894	0.105
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.895	0.105
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.895	0.105
R40 Somnolence, stupor and coma	0.000	0.895	0.105
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.896	0.104
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.896	0.104
I37.0 Pulmonary valve stenosis	0.000	0.897	0.103
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.900	0.100
R43.0 Anosmia	0.001	0.905	0.094
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.908	0.092
I31.0 Chronic adhesive pericarditis	0.000	0.912	0.088
I02 Rheumatic chorea	0.000	0.917	0.082
I01 Rheumatic fever with heart involvement	0.000	0.917	0.082
I00 Rheumatic fever without mention of heart involvement	0.000	0.920	0.080
Z95.2 Presence of prosthetic heart valve	0.000	0.921	0.079
I47 Paroxysmal tachycardia	0.000	0.921	0.079
I31.3 Pericardial effusion (noninflammatory)	0.000	0.922	0.078
Chapter V Mental and behavioural disorders	0.000	0.923	0.077
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.923	0.077
I05-I09 Chronic rheumatic heart diseases	0.000	0.925	0.075
I49.9 Cardiac arrhythmia, unspecified	0.000	0.925	0.075
I45 Other conduction disorders	0.000	0.925	0.075
I30 Acute pericarditis	0.000	0.929	0.071
I10-I15 Hypertensive diseases	0.000	0.930	0.070
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.930	0.070
I45.5 Other specified heart block	0.000	0.931	0.069
R40.1 Stupor	0.000	0.932	0.068
F60-F69 Disorders of adult personality and behaviour	0.000	0.933	0.067
I11 Hypertensive heart disease	0.000	0.934	0.066
I47.2 Ventricular tachycardia	0.000	0.934	0.066
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.938	0.062
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.939	0.061
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.940	0.060
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.940	0.059
I01.8 Other acute rheumatic heart disease	0.000	0.940	0.059
I01.2 Acute rheumatic myocarditis	0.000	0.940	0.059
I01.1 Acute rheumatic endocarditis	0.000	0.940	0.059
I01.0 Acute rheumatic pericarditis	0.000	0.940	0.059
I02.9 Rheumatic chorea without heart involvement	0.000	0.940	0.059
I02.0 Rheumatic chorea with heart involvement	0.000	0.940	0.059
I45.8 Other specified conduction disorders	0.000	0.943	0.057
F22 Persistent delusional disorders	0.000	0.943	0.057
I08 Multiple valve diseases	0.000	0.944	0.056
I45.3 Trifascicular block	0.000	0.944	0.056
I09 Other rheumatic heart diseases	0.000	0.945	0.055
F50 Eating disorders	0.000	0.945	0.055
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.945	0.055
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.945	0.055
F70-F79 Mental retardation	0.000	0.946	0.054
F80-F89 Disorders of psychological development	0.000	0.946	0.054
F22.0 Delusional disorder	0.000	0.946	0.054
I45.6 Preexcitation syndrome	0.000	0.947	0.053
I28 Other diseases of pulmonary vessels	0.000	0.947	0.053
I45.0 Right fascicular block	0.000	0.947	0.053
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.947	0.053
F69 Unspecified disorder of adult personality and behaviour	0.000	0.947	0.053
F61 Mixed and other personality disorders	0.000	0.947	0.053
F64 Gender identity disorders	0.000	0.948	0.052
I27 Other pulmonary heart diseases	0.000	0.949	0.051
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.949	0.051
I47.0 Reentry ventricular arrhythmia	0.000	0.949	0.051
F50.0 Anorexia nervosa	0.000	0.949	0.051
F60 Specific personality disorders	0.000	0.950	0.050
I08.8 Other multiple valve diseases	0.000	0.950	0.050
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.950	0.050
I45.4 Nonspecific intraventricular block	0.000	0.952	0.048
F68 Other disorders of adult personality and behaviour	0.000	0.952	0.048
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.952	0.048
F65 Disorders of sexual preference	0.000	0.952	0.048
F63 Habit and impulse disorders	0.000	0.952	0.048
I07 Rheumatic tricuspid valve diseases	0.000	0.952	0.048
F99-F99 Unspecified mental disorder	0.000	0.953	0.047
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.953	0.047
I13 Hypertensive heart and renal disease	0.000	0.954	0.046
F22.9 Persistent delusional disorder, unspecified	0.000	0.954	0.046
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.954	0.046
I06 Rheumatic aortic valve diseases	0.000	0.955	0.045
F25 Schizoaffective disorders	0.000	0.955	0.045
F81 Specific developmental disorders of scholastic skills	0.000	0.955	0.045
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.955	0.044
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.956	0.044
F55 Abuse of non-dependence-producing substances	0.000	0.956	0.044
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.000	0.956	0.044
I15 Secondary hypertension	0.000	0.956	0.044
Z45.2 Adjustment and management of vascular access device	0.000	0.957	0.043
F28 Other nonorganic psychotic disorders	0.000	0.957	0.043
F24 Induced delusional disorder	0.000	0.957	0.043
F21 Schizotypal disorder	0.000	0.957	0.043
I30.8 Other forms of acute pericarditis	0.000	0.957	0.042
I27.0 Primary pulmonary hypertension	0.000	0.957	0.043
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.957	0.043
F51 Nonorganic sleep disorders	0.000	0.957	0.042
F23 Acute and transient psychotic disorders	0.000	0.958	0.042
F50.9 Eating disorder, unspecified	0.000	0.958	0.042
F64.0 Transsexualism	0.000	0.958	0.041
I09.9 Rheumatic heart disease, unspecified	0.000	0.959	0.041
I27.8 Other specified pulmonary heart diseases	0.000	0.959	0.041
Z45 Adjustment and management of implanted device	0.000	0.959	0.041
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.959	0.041
F60.8 Other specific personality disorders	0.000	0.959	0.041
F22.8 Other persistent delusional disorders	0.000	0.959	0.041
I34 Nonrheumatic mitral valve disorders	0.000	0.959	0.041
I09.8 Other specified rheumatic heart diseases	0.000	0.960	0.040
I09.2 Chronic rheumatic pericarditis	0.000	0.960	0.040
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.960	0.040
I09.0 Rheumatic myocarditis	0.000	0.960	0.040
R29.6 Tendency to fall, not elsewhere classified	0.000	0.960	0.040
F50.8 Other eating disorders	0.000	0.960	0.040
F50.5 Vomiting associated with other psychological disturbances	0.000	0.960	0.040
F50.4 Overeating associated with other psychological disturbances	0.000	0.960	0.040
F50.3 Atypical bulimia nervosa	0.000	0.960	0.040
F50.1 Atypical anorexia nervosa	0.000	0.960	0.040
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.960	0.040
F60.0 Paranoid personality disorder	0.000	0.960	0.040
F60.5 Anankastic personality disorder	0.000	0.960	0.039
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.961	0.039
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.000	0.961	0.039
F93 Emotional disorders with onset specific to childhood	0.000	0.961	0.039
F92 Mixed disorders of conduct and emotions	0.000	0.961	0.039
F91 Conduct disorders	0.000	0.961	0.039
F90 Hyperkinetic disorders	0.000	0.961	0.039
F78 Other mental retardation	0.000	0.961	0.039
F73 Profound mental retardation	0.000	0.961	0.039
F72 Severe mental retardation	0.000	0.961	0.039
F71 Moderate mental retardation	0.000	0.961	0.039
F70 Mild mental retardation	0.000	0.961	0.039
F89 Unspecified disorder of psychological development	0.000	0.961	0.039
F88 Other disorders of psychological development	0.000	0.961	0.039
F83 Mixed specific developmental disorders	0.000	0.961	0.039
F82 Specific developmental disorder of motor function	0.000	0.961	0.039
I08.9 Multiple valve disease, unspecified	0.000	0.961	0.039
M84 Disorders of continuity of bone	0.000	0.961	0.039
F60.7 Dependent personality disorder	0.000	0.961	0.039
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.961	0.039
F50.2 Bulimia nervosa	0.000	0.961	0.039
F84 Pervasive developmental disorders	0.000	0.961	0.038
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.962	0.038
I28.1 Aneurysm of pulmonary artery	0.000	0.962	0.038
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.962	0.038
F95 Tic disorders	0.000	0.962	0.038
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.962	0.038
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.962	0.038
F79 Unspecified mental retardation	0.000	0.962	0.038
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.962	0.038
F64.9 Gender identity disorder, unspecified	0.000	0.962	0.037
F64.8 Other gender identity disorders	0.000	0.962	0.037
F64.2 Gender identity disorder of childhood	0.000	0.962	0.037
F64.1 Dual-role transvestism	0.000	0.962	0.037
F25.1 Schizoaffective disorder, depressive type	0.000	0.963	0.037
I30.1 Infective pericarditis	0.000	0.963	0.037
I27.1 Kyphoscoliotic heart disease	0.000	0.963	0.037
F60.4 Histrionic personality disorder	0.000	0.964	0.036
F60.1 Schizoid personality disorder	0.000	0.964	0.036
M84.4 Pathological fracture, not elsewhere classified	0.000	0.964	0.036
F60.2 Dissocial personality disorder	0.000	0.964	0.036
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.964	0.036
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.964	0.036
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.964	0.036
I28.8 Other specified diseases of pulmonary vessels	0.000	0.964	0.036
R40.2 Coma, unspecified	0.000	0.964	0.036
I27.2 Other secondary pulmonary hypertension	0.000	0.964	0.036
I15.0 Renovascular hypertension	0.000	0.964	0.036
F63.9 Habit and impulse disorder, unspecified	0.000	0.965	0.035
F63.8 Other habit and impulse disorders	0.000	0.965	0.035
F63.3 Trichotillomania	0.000	0.965	0.035
F63.2 Pathological stealing [kleptomania]	0.000	0.965	0.035
F63.1 Pathological fire-setting [pyromania]	0.000	0.965	0.035
F63.0 Pathological gambling	0.000	0.965	0.035
F65.9 Disorder of sexual preference, unspecified	0.000	0.965	0.035
F65.8 Other disorders of sexual preference	0.000	0.965	0.035
F65.6 Multiple disorders of sexual preference	0.000	0.965	0.035
F65.5 Sadomasochism	0.000	0.965	0.035
F65.4 Paedophilia	0.000	0.965	0.035
F65.3 Voyeurism	0.000	0.965	0.035
F65.2 Exhibitionism	0.000	0.965	0.035
F65.1 Fetishistic transvestism	0.000	0.965	0.035
F65.0 Fetishism	0.000	0.965	0.035
F66.9 Psychosexual development disorder, unspecified	0.000	0.965	0.035
F66.8 Other psychosexual development disorders	0.000	0.965	0.035
F66.2 Sexual relationship disorder	0.000	0.965	0.035
F66.1 Egodystonic sexual orientation	0.000	0.965	0.035
F66.0 Sexual maturation disorder	0.000	0.965	0.035
F68.8 Other specified disorders of adult personality and behaviour	0.000	0.965	0.035
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.000	0.965	0.035
F68.0 Elaboration of physical symptoms for psychological reasons	0.000	0.965	0.035
F60.6 Anxious [avoidant] personality disorder	0.000	0.965	0.035
I07.9 Tricuspid valve disease, unspecified	0.000	0.965	0.034
I07.8 Other tricuspid valve diseases	0.000	0.965	0.034
I07.2 Tricuspid stenosis with insufficiency	0.000	0.965	0.034
I07.0 Tricuspid stenosis	0.000	0.965	0.034
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.966	0.034
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.966	0.034
F43 Reaction to severe stress, and adjustment disorders	0.000	0.966	0.034
F62.8 Other enduring personality changes	0.000	0.966	0.034
F62.1 Enduring personality change after psychiatric illness	0.000	0.966	0.034
F62.0 Enduring personality change after catastrophic experience	0.000	0.966	0.034
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.966	0.034
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.966	0.033
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.966	0.033
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.966	0.033
F60.3 Emotionally unstable personality disorder	0.000	0.967	0.033
I05 Rheumatic mitral valve diseases	0.000	0.967	0.033
I06.8 Other rheumatic aortic valve diseases	0.000	0.967	0.033
I06.1 Rheumatic aortic insufficiency	0.000	0.967	0.033
F25.0 Schizoaffective disorder, manic type	0.000	0.967	0.033
F51.5 Nightmares	0.000	0.967	0.032
F25.8 Other schizoaffective disorders	0.000	0.967	0.032
F25.2 Schizoaffective disorder, mixed type	0.000	0.967	0.032
F81.8 Other developmental disorders of scholastic skills	0.000	0.968	0.032
F81.3 Mixed disorder of scholastic skills	0.000	0.968	0.032
F81.2 Specific disorder of arithmetical skills	0.000	0.968	0.032
F81.1 Specific spelling disorder	0.000	0.968	0.032
F81.0 Specific reading disorder	0.000	0.968	0.032
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.968	0.032
F62.9 Enduring personality change, unspecified	0.000	0.968	0.032
I34.1 Mitral (valve) prolapse	0.000	0.968	0.032
F53.9 Puerperal mental disorder, unspecified	0.000	0.968	0.032
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.968	0.032
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.968	0.032
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.968	0.032
M84.3 Stress fracture, not elsewhere classified	0.000	0.968	0.032
I45.9 Conduction disorder, unspecified	0.000	0.968	0.032
I30.9 Acute pericarditis, unspecified	0.000	0.968	0.031
I15.8 Other secondary hypertension	0.000	0.968	0.031
I15.2 Hypertension secondary to endocrine disorders	0.000	0.968	0.031
F51.3 Sleepwalking [somnambulism]	0.000	0.968	0.031
I06.0 Rheumatic aortic stenosis	0.000	0.969	0.031
I45.2 Bifascicular block	0.000	0.969	0.031
Z45.8 Adjustment and management of other implanted devices	0.000	0.969	0.031
F51.9 Nonorganic sleep disorder, unspecified	0.000	0.969	0.030
F51.8 Other nonorganic sleep disorders	0.000	0.969	0.030
F51.4 Sleep terrors [night terrors]	0.000	0.969	0.030
F51.2 Nonorganic disorder of the sleep-wake schedule	0.000	0.969	0.030
F51.1 Nonorganic hypersomnia	0.000	0.969	0.030
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.969	0.030
F23.8 Other acute and transient psychotic disorders	0.000	0.969	0.031
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.969	0.031
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.969	0.031
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.969	0.031
I15.9 Seconday hypertension, unspecified	0.000	0.969	0.031
R40.0 Somnolence	0.000	0.969	0.031
F44 Dissociative [conversion] disorders	0.000	0.970	0.030
I60-I69 Cerebrovascular diseases	0.000	0.970	0.030
I26 Pulmonary embolism	0.000	0.970	0.030
F43.9 Reaction to severe stress, unspecified	0.000	0.970	0.030
F84.5 Asperger's syndrome	0.000	0.970	0.030
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.970	0.029
F29 Unspecified nonorganic psychosis	0.000	0.971	0.029
M84.0 Malunion of fracture	0.000	0.971	0.029
Z45.3 Adjustment and management of implanted hearing device	0.000	0.971	0.029
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.971	0.029
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.971	0.028
F43.1 Posttraumatic stress disorder	0.000	0.971	0.029
F90.9 Hyperkinetic disorder, unspecified	0.000	0.971	0.028
F90.8 Other hyperkinetic disorders	0.000	0.971	0.028
F90.1 Hyperkinetic conduct disorder	0.000	0.971	0.028
F90.0 Disturbance of activity and attention	0.000	0.971	0.028
F91.9 Conduct disorder, unspecified	0.000	0.971	0.028
F91.8 Other conduct disorders	0.000	0.971	0.028
F91.3 Oppositional defiant disorder	0.000	0.971	0.028
F91.2 Socialised conduct disorder	0.000	0.971	0.028
F91.1 Unsocialised conduct disorder	0.000	0.971	0.028

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations