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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1579219
log Bayes Factor = 8.68636
Chromosome 6   position 30,224,305  (GRCh37) Explore rs1579219 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10.9 Without complications
0.000 0.065 0.935
E10 Insulin-dependent diabetes mellitus
0.000 0.081 0.919
E10.3 With ophthalmic complications
0.000 0.121 0.879
E10.5 With peripheral circulatory complications
0.000 0.182 0.818
E10.1 With ketoacidosis
0.000 0.237 0.763
E10.6 With other specified complications
0.000 0.289 0.711
E10.0 With coma
0.000 0.296 0.704
E10.8 With unspecified complications
0.000 0.300 0.700
E10-E14 Diabetes mellitus
0.000 0.326 0.674
E10.7 With multiple complications
0.000 0.341 0.659
E10.4 With neurological complications
0.000 0.473 0.527
E13 Other specified diabetes mellitus
0.000 0.484 0.515
E14 Unspecified diabetes mellitus
0.000 0.497 0.503
E10.2 With renal complications
0.000 0.505 0.495
E05.9 Thyrotoxicosis, unspecified
0.000 0.517 0.483
E12 Malnutrition-related diabetes mellitus
0.000 0.517 0.483
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.519 0.481
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.531 0.469
E00-E07 Disorders of thyroid gland
0.000 0.532 0.468
E14.3 With ophthalmic complications
0.000 0.534 0.466
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.543 0.457
E11 Non-insulin-dependent diabetes mellitus
0.000 0.546 0.454
E11.5 With peripheral circulatory complications
0.000 0.594 0.406
E13.9 Without complications
0.000 0.598 0.402
E11.4 With neurological complications
0.000 0.607 0.393
E03 Other hypothyroidism
0.000 0.610 0.390
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.630 0.370
E13.8 With unspecified complications
0.000 0.630 0.370
E13.7 With multiple complications
0.000 0.630 0.370
E13.6 With other specified complications
0.000 0.630 0.370
E13.5 With peripheral circulatory complications
0.000 0.630 0.370
E13.4 With neurological complications
0.000 0.630 0.370
E13.3 With ophthalmic complications
0.000 0.630 0.370
E13.2 With renal complications
0.000 0.630 0.370
E13.1 With ketoacidosis
0.000 0.630 0.370
E13.0 With coma
0.000 0.630 0.370
E14.7 With multiple complications
0.000 0.639 0.360
E14.6 With other specified complications
0.000 0.639 0.360
E14.5 With peripheral circulatory complications
0.000 0.639 0.360
E14.4 With neurological complications
0.000 0.639 0.360
E14.2 Withrenal complications
0.000 0.639 0.360
E14.0 With coma
0.000 0.639 0.360
E11.1 With ketoacidosis
0.000 0.641 0.359
E07 Other disorders of thyroid
0.000 0.650 0.350
E12.9 Without complications
0.000 0.653 0.346
E12.8 With unspecified complications
0.000 0.653 0.346
E12.7 With multiple complications
0.000 0.653 0.346
E12.6 With other specified complications
0.000 0.653 0.346
E12.5 With peripheral circulatory complications
0.000 0.653 0.346
E12.4 With neurological complications
0.000 0.653 0.346
E12.3 With ophthalmic complications
0.000 0.653 0.346
E12.2 With renal complications
0.000 0.653 0.346
E12.1 With ketoacidosis
0.000 0.653 0.346
E12.0 With coma
0.000 0.653 0.346
E05.5 Thyroid crisis or storm
0.000 0.655 0.345
E05.4 Thyrotoxicosis factitia
0.000 0.655 0.345
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.655 0.345
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.655 0.345
E14.1 With ketoacidosis
0.000 0.661 0.339
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.664 0.336
E00 Congenital iodine-deficiency syndrome
0.000 0.664 0.336
E40-E46 Malnutrition
0.000 0.666 0.334
E11.3 With ophthalmic complications
0.000 0.666 0.334
E14.8 With unspecified complications
0.000 0.671 0.329
E11.0 With coma
0.000 0.673 0.326
E11.7 With multiple complications
0.000 0.674 0.326
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.682 0.317
E11.8 With unspecified complications
0.000 0.687 0.313
E05.8 Other thyrotoxicosis
0.000 0.691 0.309
E03.9 Hypothyroidism, unspecified
0.000 0.693 0.307
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.696 0.304
E03.8 Other specified hypothyroidism
0.000 0.697 0.303
E16 Other disorders of pancreatic internal secretion
0.000 0.701 0.299
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.705 0.294
E07.8 Other specified disorders of thyroid
0.000 0.708 0.292
E65-E68 Obesity and other hyperalimentation
0.000 0.719 0.281
E03.5 Myxoedema coma
0.000 0.720 0.279
E03.4 Atrophy of thyroid (acquired)
0.000 0.720 0.279
E03.3 Postinfectious hypothyroidism
0.000 0.720 0.279
E03.1 Congenital hypothyroidism without goitre
0.000 0.720 0.279
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.720 0.279
E15 Nondiabetic hypoglycaemic coma
0.000 0.735 0.265
K90 Intestinal malabsorption
0.000 0.741 0.259
E11.6 With other specified complications
0.000 0.744 0.256
E07.1 Dyshormogenetic goitre
0.000 0.749 0.251
E07.0 Hypersecretion of calcitonin
0.000 0.749 0.251
E50-E64 Other nutritional deficiencies
0.000 0.752 0.248
E16.2 Hypoglycaemia, unspecified
0.000 0.757 0.243
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.759 0.241
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.759 0.241
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.759 0.241
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.759 0.241
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.759 0.241
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.759 0.241
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.759 0.241
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.759 0.241
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.760 0.240
E45 Retarded development following protein-energy malnutrition
0.000 0.760 0.240
E43 Unspecified severe protein-energy malnutrition
0.000 0.760 0.240
E42 Marasmic kwashiorkor
0.000 0.760 0.240
E41 Nutritional marasmus
0.000 0.760 0.240
E40 Kwashiorkor
0.000 0.760 0.240
E46 Unspecified protein-energy malnutrition
0.000 0.762 0.238
E65 Localised adiposity
0.000 0.769 0.231
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.771 0.229
E04 Other non-toxic goitre
0.000 0.783 0.217
E20-E35 Disorders of other endocrine glands
0.000 0.785 0.215
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.785 0.214
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.785 0.214
E16.4 Abnormal secretion of gastrin
0.000 0.785 0.214
E16.3 Increased secretion of glucagon
0.000 0.785 0.214
E11.2 With renal complications
0.000 0.791 0.208
E16.1 Other hypoglycaemia
0.000 0.793 0.206
E07.9 Disorder of thyroid, unspecified
0.000 0.795 0.205
E67 Other hyperalimentation
0.000 0.798 0.202
E68 Sequelae of hyperalimentation
0.000 0.798 0.202
E53 Deficiency of other B group vitamins
0.000 0.812 0.188
K90.8 Other intestinal malabsorption
0.000 0.814 0.186
K90.3 Pancreatic steatorrhoea
0.000 0.814 0.186
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.814 0.186
K90.1 Tropical sprue
0.000 0.814 0.186
E34 Other endocrine disorders
0.000 0.821 0.179
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.822 0.178
E63 Other nutritional deficiencies
0.000 0.822 0.178
E56 Other vitamin deficiencies
0.000 0.822 0.178
E51 Thiamine deficiency
0.000 0.822 0.178
E50 Vitamin A deficiency
0.000 0.822 0.178
E60 Dietary zinc deficiency
0.000 0.822 0.178
E59 Dietary selenium deficiency
0.000 0.822 0.178
E58 Dietary calcium deficiency
0.000 0.822 0.178
E54 Ascorbic acid deficiency
0.000 0.822 0.178
E52 Niacin deficiency [pellagra]
0.000 0.822 0.178
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.825 0.175
E44.1 Mild protein-energy malnutrition
0.000 0.828 0.172
E44.0 Moderate protein-energy malnutrition
0.000 0.828 0.172
E27 Other disorders of adrenal gland
0.000 0.828 0.172
E24 Cushing's syndrome
0.000 0.834 0.166
E14.9 Without complications
0.000 0.837 0.163
E27.1 Primary adrenocortical insufficiency
0.000 0.839 0.161
E20 Hypoparathyroidism
0.000 0.840 0.160
E04.8 Other specified non-toxic goitre
0.000 0.844 0.156
E04.0 Non-toxic diffuse goitre
0.000 0.844 0.155
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.846 0.154
E32 Diseases of thymus
0.000 0.846 0.154
E31 Polyglandular dysfunction
0.000 0.846 0.154
E30 Disorders of puberty, not elsewhere classified
0.000 0.846 0.154
E25 Adrenogenital disorders
0.000 0.846 0.154
E04.2 Non-toxic multinodular goitre
0.000 0.851 0.149
E53.8 Deficiency of other specified B group vitamins
0.000 0.852 0.148
E67.8 Other specified hyperalimentation
0.000 0.855 0.145
E67.3 Hypervitaminosis D
0.000 0.855 0.145
E67.2 Megavitamin-B6 syndrome
0.000 0.855 0.145
E67.1 Hypercarotenaemia
0.000 0.855 0.145
E67.0 Hypervitaminosis A
0.000 0.855 0.145
E61 Deficiency of other nutrient elements
0.000 0.856 0.144
E34.8 Other specified endocrine disorders
0.000 0.857 0.143
E06 Thyroiditis
0.005 0.857 0.138
E28 Ovarian dysfunction
0.000 0.857 0.143
E26 Hyperaldosteronism
0.000 0.859 0.141
E34.0 Carcinoid syndrome
0.000 0.861 0.139
E29 Testicular dysfunction
0.000 0.863 0.137
N40 Hyperplasia of prostate
0.137 0.863 0.000
E53.1 Pyridoxine deficiency
0.000 0.865 0.135
E53.0 Riboflavin deficiency
0.000 0.865 0.135
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.865 0.135
E04.1 Non-toxic single thyroid nodule
0.000 0.866 0.134
E34.9 Endocrine disorder, unspecified
0.000 0.869 0.131
E24.9 Cushing's syndrome, unspecified
0.000 0.869 0.131
E53.9 Vitamin B deficiency, unspecified
0.000 0.870 0.130
E34.5 Androgen resistance syndrome
0.000 0.872 0.128
E34.4 Constitutional tall stature
0.000 0.872 0.128
E34.3 Short stature, not elsewhere classified
0.000 0.872 0.128
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.872 0.128
E34.1 Other hypersecretion of intestinal hormones
0.000 0.872 0.128
E50.9 Vitamin A deficiency, unspecified
0.000 0.872 0.128
E50.8 Other manifestations of vitamin A deficiency
0.000 0.872 0.128
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.872 0.128
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.872 0.128
E50.5 Vitamin A deficiency with night blindness
0.000 0.872 0.128
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.872 0.128
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.872 0.128
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.872 0.128
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.872 0.128
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.872 0.128
E51.9 Thiamine deficiency, unspecified
0.000 0.872 0.128
E51.8 Other manifestations of thiamine deficiency
0.000 0.872 0.128
E51.2 Wernicke's encephalopathy
0.000 0.872 0.128
E51.1 Beriberi
0.000 0.872 0.128
E56.9 Vitamin deficiency, unspecified
0.000 0.872 0.128
E56.8 Deficiency of other vitamins
0.000 0.872 0.128
E56.1 Deficiency of vitamin K
0.000 0.872 0.128
E56.0 Deficiency of vitamin E
0.000 0.872 0.128
E63.9 Nutritional deficiency, unspecified
0.000 0.872 0.128
E63.8 Other specified nutritional deficiencies
0.000 0.872 0.128
E63.1 Imbalance of constituents of food intake
0.000 0.872 0.128
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.872 0.128
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.872 0.128
E64.8 Sequelae of other nutritional deficiencies
0.000 0.872 0.128
E64.3 Sequelae of rickets
0.000 0.872 0.128
E64.2 Sequelae of vitamin C deficiency
0.000 0.872 0.128
E64.1 Sequelae of vitamin A deficiency
0.000 0.872 0.128
E64.0 Sequelae of protein-energy malnutrition
0.000 0.872 0.128
E55 Vitamin D deficiency
0.000 0.875 0.125
E22 Hyperfunction of pituitary gland
0.000 0.876 0.124
E27.5 Adrenomedullary hyperfunction
0.000 0.877 0.123
E27.0 Other adrenocortical overactivity
0.000 0.877 0.123
E20.9 Hypoparathyroidism, unspecified
0.000 0.879 0.121
K90.9 Intestinal malabsorption, unspecified
0.000 0.880 0.120
E24.2 Drug-induced Cushing's syndrome
0.000 0.880 0.120
E24.8 Other Cushing's syndrome
0.000 0.881 0.119
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.881 0.119
E24.3 Ectopic ACTH syndrome
0.000 0.881 0.119
E24.1 Nelson's syndrome
0.000 0.881 0.119
E24.0 Pituitary-dependent Cushing's disease
0.000 0.881 0.119
E20.8 Other hypoparathyroidism
0.000 0.885 0.115
E20.1 Pseudohypoparathyroidism
0.000 0.885 0.115
E20.0 Idiopathic hypoparathyroidism
0.000 0.885 0.115
E27.2 Addisonian crisis
0.000 0.886 0.114
E25.9 Adrenogenital disorder, unspecified
0.000 0.889 0.111
E25.8 Other adrenogenital disorders
0.000 0.889 0.111
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.889 0.111
E30.9 Disorder of puberty, unspecified
0.000 0.889 0.111
E30.8 Other disorders of puberty
0.000 0.889 0.111
E30.1 Precocious puberty
0.000 0.889 0.111
E30.0 Delayed puberty
0.000 0.889 0.111
E31.9 Polyglandular dysfunction, unspecified
0.000 0.889 0.111
E31.8 Other polyglandular dysfunction
0.000 0.889 0.111
E31.1 Polyglandular hyperfunction
0.000 0.889 0.111
E31.0 Autoimmune polyglandular failure
0.000 0.889 0.111
E32.9 Disease of thymus, unspecified
0.000 0.889 0.111
E32.8 Other diseases of thymus
0.000 0.889 0.111
E32.1 Abscess of thymus
0.000 0.889 0.111
E32.0 Persistent hyperplasia of thymus
0.000 0.889 0.111
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.889 0.111
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.889 0.111
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.889 0.111
E61.9 Deficiency of nutrient element, unspecified
0.000 0.897 0.103
E61.8 Deficiency of other specified nutrient elements
0.000 0.897 0.103
E61.7 Deficiency of multiple nutrient elements
0.000 0.897 0.103
E61.6 Vanadium deficiency
0.000 0.897 0.103
E61.5 Molybdenum deficiency
0.000 0.897 0.103
E61.4 Chromium deficiency
0.000 0.897 0.103
E61.3 Manganese deficiency
0.000 0.897 0.103
E61.0 Copper deficiency
0.000 0.897 0.103
E23 Hypofunction and other disorders of pituitary gland
0.000 0.897 0.103
E06.4 Drug-induced thyroiditis
0.004 0.897 0.099
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.004 0.897 0.099
E06.1 Subacute thyroiditis
0.004 0.897 0.099
E06.0 Acute thyroiditis
0.004 0.897 0.099
E28.9 Ovarian dysfunction, unspecified
0.000 0.897 0.102
E28.8 Other ovarian dysfunction
0.000 0.897 0.102
E28.1 Androgen excess
0.000 0.897 0.102
E28.0 Oestrogen excess
0.000 0.897 0.102
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.898 0.102
E27.8 Other specified disorders of adrenal gland
0.000 0.898 0.101
E26.9 Hyperaldosteronism, unspecified
0.000 0.899 0.101
E26.8 Other hyperaldosteronism
0.000 0.899 0.101
E26.1 Secondary hyperaldosteronism
0.000 0.899 0.101
E27.9 Disorder of adrenal gland, unspecified
0.000 0.899 0.100
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.900 0.100
E28.3 Primary ovarian failure
0.000 0.901 0.099
E29.9 Testicular dysfunction, unspecified
0.000 0.901 0.099
E29.8 Other testicular dysfunction
0.000 0.901 0.099
E29.0 Testicular hyperfunction
0.000 0.901 0.099
E04.9 Non-toxic goitre, unspecified
0.000 0.903 0.097
E22.1 Hyperprolactinaemia
0.000 0.903 0.097
E28.2 Polycystic ovarian syndrome
0.000 0.904 0.096
E06.5 Other chronic thyroiditis
0.004 0.908 0.088
E61.2 Magnesium deficiency
0.000 0.908 0.092
E55.0 Rickets, active
0.000 0.910 0.090
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.911 0.089
E22.8 Other hyperfunction of pituitary gland
0.000 0.911 0.089
E26.0 Primary hyperaldosteronism
0.000 0.912 0.088
E61.1 Iron deficiency
0.000 0.915 0.085
E21.3 Hyperparathyroidism, unspecified
0.000 0.918 0.082
E29.1 Testicular hypofunction
0.000 0.918 0.082
E06.9 Thyroiditis, unspecified
0.004 0.920 0.076
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.920 0.080
J34.8 Other specified disorders of nose and nasal sinuses
0.079 0.921 0.000
J34 Other disorders of nose and nasal sinuses
0.078 0.922 0.000
J34.2 Deviated nasal septum
0.077 0.923 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.926 0.074
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.926 0.074
E23.1 Drug-induced hypopituitarism
0.000 0.926 0.074
E23.2 Diabetes insipidus
0.000 0.926 0.073
E23.6 Other disorders of pituitary gland
0.000 0.927 0.073
J34.3 Hypertrophy of nasal turbinates
0.073 0.927 0.000
E70-E90 Metabolic disorders
0.000 0.928 0.072
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.928 0.072
E21.4 Other specified disorders of parathyroid gland
0.000 0.928 0.072
E21.2 Other hyperparathyroidism
0.000 0.928 0.072
E11.9 Without complications
0.000 0.931 0.069
E66 Obesity
0.000 0.933 0.067
E83.1 Disorders of iron metabolism
0.000 0.935 0.065
E83 Disorders of mineral metabolism
0.000 0.941 0.059
E73 Lactose intolerance
0.000 0.941 0.059
E88 Other metabolic disorders
0.000 0.942 0.058
E22.0 Acromegaly and pituitary gigantism
0.000 0.942 0.057
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.945 0.055
J34.1 Cyst and mucocele of nose and nasal sinus
0.055 0.945 0.000
J32 Chronic sinusitis
0.054 0.946 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.946 0.054
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.946 0.053
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.948 0.052
E84 Cystic fibrosis
0.000 0.948 0.052
E77 Disorders of glycoprotein metabolism
0.000 0.948 0.052
E76 Disorders of glycosaminoglycan metabolism
0.000 0.948 0.052
E72 Other disorders of amino-acid metabolism
0.000 0.948 0.052
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.948 0.052
E70 Disorders of aromatic amino-acid metabolism
0.000 0.948 0.052
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.948 0.052
J30-J39 Other diseases of upper respiratory tract
0.050 0.950 0.000
J32.9 Chronic sinusitis, unspecified
0.050 0.950 0.000
E85 Amyloidosis
0.000 0.950 0.050
J32.2 Chronic ethmoidal sinusitis
0.050 0.950 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.951 0.049
E73.9 Lactose intolerance, unspecified
0.000 0.951 0.049
E66.1 Drug-induced obesity
0.000 0.952 0.048
J32.8 Other chronic sinusitis
0.048 0.952 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.952 0.048
J32.4 Chronic pansinusitis
0.046 0.954 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.045 0.955 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.956 0.044
E88.2 Lipomatosis, not elsewhere classified
0.000 0.956 0.044
J32.1 Chronic frontal sinusitis
0.043 0.957 0.000
E80.4 Gilbert's syndrome
0.000 0.957 0.043
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.957 0.042
E83.8 Other disorders of mineral metabolism
0.000 0.957 0.042
E83.2 Disorders of zinc metabolism
0.000 0.957 0.042
E83.0 Disorders of copper metabolism
0.000 0.957 0.042
O34.2 Maternal care due to uterine scar from previous surgery
0.000 0.957 0.043
E73.8 Other lactose intolerance
0.000 0.958 0.042
E73.1 Secondary lactase deficiency
0.000 0.958 0.042
E73.0 Congenital lactase deficiency
0.000 0.958 0.042
E88.9 Metabolic disorder, unspecified
0.000 0.958 0.042
E88.3 Tumour lysis syndrome
0.000 0.958 0.042
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.958 0.042
J35 Chronic diseases of tonsils and adenoids
0.042 0.958 0.000
J31.0 Chronic rhinitis
0.042 0.958 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.041 0.958 0.000
R04.0 Epistaxis
0.042 0.958 0.000
E66.0 Obesity due to excess calories
0.000 0.959 0.041
J32.3 Chronic sphenoidal sinusitis
0.041 0.959 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.960 0.040
J34.0 Abscess, furuncle and carbuncle of nose
0.040 0.960 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.960 0.040
E80.6 Other disorders of bilirubin metabolism
0.000 0.960 0.040
E80.5 Crigler-Najjar syndrome
0.000 0.960 0.040
E80.3 Defects of catalase and peroxydase
0.000 0.960 0.040
E80.2 Other porphyria
0.000 0.960 0.040
E80.1 Porphyria cutanea tarda
0.000 0.960 0.040
E80.0 Hereditary erythropoietic porphyria
0.000 0.960 0.040
E85.9 Amyloidosis, unspecified
0.000 0.960 0.039
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.961 0.039
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.961 0.039
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.961 0.039
E74.2 Disorders of galactose metabolism
0.000 0.961 0.039
E74.1 Disorders of fructose metabolism
0.000 0.961 0.039
E74.0 Glycogen storage disease
0.000 0.961 0.039
E88.8 Other specified metabolic disorders
0.000 0.962 0.038
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.962 0.038
C34.3 Lower lobe, bronchus or lung
0.000 0.962 0.038
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.962 0.037
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.962 0.037
E70.3 Albinism
0.000 0.962 0.037
E70.2 Disorders of tyrosine metabolism
0.000 0.962 0.037
E70.1 Other hyperphenylalaninaemias
0.000 0.962 0.037
E70.0 Classical phenylketonuria
0.000 0.962 0.037
E71.3 Disorders of fatty-acid metabolism
0.000 0.962 0.037
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.962 0.037
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.962 0.037
E71.0 Maple-syrup-urine disease
0.000 0.962 0.037
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.962 0.037
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.962 0.037
E72.5 Disorders of glycine metabolism
0.000 0.962 0.037
E72.4 Disorders of ornithine metabolism
0.000 0.962 0.037
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.962 0.037
E72.2 Disorders of urea cycle metabolism
0.000 0.962 0.037
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.962 0.037
E72.0 Disorders of amino-acid transport
0.000 0.962 0.037
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.962 0.037
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.962 0.037
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.962 0.037
E76.2 Other mucopolysaccharidoses
0.000 0.962 0.037
E76.1 Mucopolysaccharidosis, type II
0.000 0.962 0.037
E76.0 Mucopolysaccharidosis, type I
0.000 0.962 0.037
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.962 0.037
E77.8 Other disorders of glycoprotein metabolism
0.000 0.962 0.037
E77.1 Defects in glycoprotein degradation
0.000 0.962 0.037
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.962 0.037
E84.9 Cystic fibrosis, unspecified
0.000 0.962 0.037
E84.8 Cystic fibrosis with other manifestations
0.000 0.962 0.037
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.962 0.037
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.962 0.037
E55.9 Vitamin D deficiency, unspecified
0.000 0.963 0.037
O34 Maternal care for known or suspected abnormality of pelvic organs
0.000 0.963 0.037
O42 Premature rupture of membranes
0.000 0.964 0.036
E85.8 Other amyloidosis
0.000 0.964 0.036
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.964 0.036
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.964 0.036
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.964 0.036
E75.6 Lipid storage disorder, unspecified
0.000 0.964 0.035
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.964 0.035
E75.3 Sphingolipidosis, unspecified
0.000 0.964 0.035
E75.2 Other sphingolipidosis
0.000 0.964 0.035
E75.1 Other gangliosidosis
0.000 0.964 0.035
E75.0 GM2 gangliosidosis
0.000 0.964 0.035
C34 Malignant neoplasm of bronchus and lung
0.000 0.964 0.036
J37 Chronic laryngitis and laryngotracheitis
0.035 0.965 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.000 0.965 0.035
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.000 0.965 0.035
E85.3 Secondary systemic amyloidosis
0.000 0.965 0.034
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.965 0.034
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.966 0.034
C34.1 Upper lobe, bronchus or lung
0.000 0.966 0.034
E87.3 Alkalosis
0.000 0.966 0.034
J31.2 Chronic pharyngitis
0.034 0.966 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.000 0.967 0.033
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.967 0.033
E75.5 Other lipid storage disorders
0.000 0.967 0.032
C34.0 Main bronchus
0.000 0.968 0.032
O32 Maternal care for known or suspected malpresentation of foetus
0.000 0.968 0.032
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.968 0.032
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.968 0.032
E79.1 Lesch-Nyhan syndrome
0.000 0.968 0.032
C34.2 Middle lobe, bronchus or lung
0.000 0.968 0.032
J31.1 Chronic nasopharyngitis
0.031 0.969 0.000
O32.1 Maternal care for breech presentation
0.000 0.969 0.031
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.030 0.970 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.970 0.030
O48 Prolonged pregnancy
0.000 0.971 0.029
E85.4 Organ-limited amyloidosis
0.000 0.971 0.029
J35.1 Hypertrophy of tonsils
0.029 0.971 0.000
E06.3 Autoimmune thyroiditis
0.008 0.971 0.021
D51 Vitamin B12 deficiency anaemia
0.000 0.971 0.029
O44 Placenta praevia
0.000 0.971 0.029
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.971 0.029
O34.8 Maternal care for other abnormalities of pelvic organs
0.000 0.972 0.028
E87.7 Fluid overload
0.000 0.972 0.028
J39 Other diseases of upper respiratory tract
0.028 0.972 0.000
L40.9 Psoriasis, unspecified
0.000 0.972 0.028
O34.3 Maternal care for cervical incompetence
0.000 0.972 0.028
O35 Maternal care for known or suspected foetal abnormality and damage
0.000 0.972 0.028
E87.4 Mixed disorder of acid-base balance
0.000 0.972 0.027
J47 Bronchiectasis
0.027 0.973 0.000
O32.2 Maternal care for transverse and oblique lie
0.000 0.973 0.027
E23.0 Hypopituitarism
0.001 0.973 0.026
O43 Placental disorders
0.000 0.973 0.027
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.000 0.973 0.026
O34.6 Maternal care for abnormality of vagina
0.000 0.973 0.026
O34.5 Maternal care for other abnormalities of gravid uterus
0.000 0.973 0.026
J35.2 Hypertrophy of adenoids
0.026 0.974 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.974 0.026
O45 Premature separation of placenta [abruptio placentae]
0.000 0.974 0.026
O34.7 Maternal care for abnormality of vulva and perineum
0.000 0.974 0.026
O42.2 Premature rupture of membranes, labour delayed by therapy
0.000 0.974 0.026
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.026 0.974 0.000
E21.0 Primary hyperparathyroidism
0.000 0.974 0.026
C34.8 Overlapping lesion of bronchus and lung
0.000 0.974 0.026
F06.7 Mild cognitive disorder
0.026 0.974 0.000
J37.1 Chronic laryngotracheitis
0.025 0.974 0.000
O31 Complications specific to multiple gestation
0.000 0.975 0.025
O40 Polyhydramnios
0.000 0.975 0.025
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.025 0.975 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.975 0.025
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.975 0.025
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.975 0.025
E89.5 Postprocedural testicular hypofunction
0.000 0.975 0.025
E89.4 Postprocedural ovarian failure
0.000 0.975 0.025
E89.1 Postprocedural hypoinsulinaemia
0.000 0.975 0.025
J37.0 Chronic laryngitis
0.025 0.975 0.000
J39.9 Disease of upper respiratory tract, unspecified
0.025 0.975 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.025 0.975 0.000
O33 Maternal care for known or suspected disproportion
0.000 0.975 0.025
O47 False labour
0.000 0.975 0.025
O32.0 Maternal care for unstable lie
0.000 0.976 0.024
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.000 0.976 0.024
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.976 0.024
O32.4 Maternal care for high head at term
0.000 0.976 0.024
O44.0 Placenta praevia specified as without haemorrhage
0.000 0.976 0.024
F00-F09 Organic, including symptomatic, mental disorders
0.024 0.976 0.000
O32.3 Maternal care for face, brow and chin presentation
0.000 0.977 0.023
O32.6 Maternal care for compound presentation
0.000 0.977 0.023
O30 Multiple gestation
0.000 0.977 0.023
O42.9 Premature rupture of membranes, unspecified
0.000 0.977 0.023
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.000 0.977 0.023
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.000 0.977 0.023
E66.8 Other obesity
0.000 0.977 0.023
O34.0 Maternal care for congenital malformation of uterus
0.000 0.977 0.023
O34.4 Maternal care for other abnormalities of cervix
0.000 0.977 0.023
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.977 0.022
J38.6 Stenosis of larynx
0.022 0.978 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.978 0.022
O34.1 Maternal care for tumour of corpus uteri
0.000 0.978 0.022
F02 Dementia in other diseases classified elsewhere
0.022 0.978 0.000
O44.1 Placenta praevia with haemorrhage
0.000 0.978 0.022
J32.0 Chronic maxillary sinusitis
0.022 0.978 0.000
O43.1 Malformation of placenta
0.000 0.978 0.022
J39.0 Retropharyngeal and parapharyngeal abscess
0.021 0.979 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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