TreeWAS – Variant ID: rs1584468

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Z72 Problems related to lifestyle	0.659	0.341
Z72.0 Tobacco use	0.657	0.343
Z70-Z76 Persons encountering health services in other circumstances	0.657	0.343
Chapter XXI Factors influencing health status and contact with health services	0.653	0.347
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.636	0.364
# Top node	0.628	0.372
Chapter XV Pregnancy, childbirth and the puerperium	0.625	0.375
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.615	0.385
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.614	0.386
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.608	0.392
R47-R49 Symptoms and signs involving speech and voice	0.603	0.397
Z60 Problems related to social environment	0.602	0.398
R47 Speech disturbances, not elsewhere classified	0.601	0.399
Chapter VIII Diseases of the ear and mastoid process	0.597	0.403
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.594	0.406
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.591	0.409
Z22 Carrier of infectious disease	0.588	0.412
O42 Premature rupture of membranes	0.587	0.413
Z72.1 Alcohol use	0.585	0.415
Z60.2 Living alone	0.577	0.423
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.570	0.430
R47.0 Dysphasia and aphasia	0.564	0.436
Z74 Problems related to care-provider dependency	0.561	0.438
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.559	0.441
O42.9 Premature rupture of membranes, unspecified	0.558	0.442
Z22.3 Carrier of other specified bacterial diseases	0.557	0.443
Z35 Supervision of high-risk pregnancy	0.555	0.445
H90-H95 Other disorders of ear	0.549	0.451
R47.1 Dysarthria and anarthria	0.549	0.451
R47.8 Other and unspecified speech disturbances	0.545	0.455
O20-O29 Other maternal disorders predominantly related to pregnancy	0.541	0.458
O36 Maternal care for other known or suspected foetal problems	0.537	0.463
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.537	0.463
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.536	0.464
Q20-Q28 Congenital malformations of the circulatory system	0.534	0.466
Chapter IV Endocrine, nutritional and metabolic diseases	0.530	0.470
R26 Abnormalities of gait and mobility	0.527	0.473
R41 Other symptoms and signs involving cognitive functions and awareness	0.527	0.473
O94-O99 Other obstetric conditions, not elsewhere classified	0.523	0.477
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.518	0.482
Chapter XX External causes of morbidity and mortality	0.515	0.485
H90 Conductive and sensorineural hearing loss	0.515	0.485
Z63 Other problems related to primary support group, including family circumstances	0.514	0.486
Z39 Postpartum care and examination	0.510	0.490
Z59 Problems related to housing and economic circumstances	0.509	0.490
Q00-Q07 Congenital malformations of the nervous system	0.509	0.491
O47 False labour	0.507	0.493
Z57 Occupational exposure to risk-factors	0.504	0.496
R41.0 Disorientation, unspecified	0.504	0.496
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.503	0.497
Chapter I Certain infectious and parasitic diseases	0.501	0.499
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.501	0.499
Q21 Congenital malformations of cardiac septa	0.500	0.500
H60-H62 Diseases of external ear	0.498	0.502
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.494	0.506
Z74.0 Reduced mobility	0.493	0.507
R26.8 Other and unspecified abnormalities of gait and mobility	0.492	0.508
H90.3 Sensorineural hearing loss, bilateral	0.490	0.510
R27 Other lack of coordination	0.489	0.510
O85-O92 Complications predominantly related to the puerperium	0.482	0.518
Z22.5 Carrier of viral hepatitis	0.481	0.518
O32 Maternal care for known or suspected malpresentation of foetus	0.481	0.519
Z72.2 Drug use	0.479	0.521
E00-E07 Disorders of thyroid gland	0.478	0.522
H65-H75 Diseases of middle ear and mastoid	0.477	0.523
S20-S29 Injuries to the thorax	0.476	0.523
Z72.9 Problem related to lifestyle, unspecified	0.473	0.527
Z72.8 Other problems related to lifestyle	0.473	0.527
Z72.6 Gambling and betting	0.473	0.527
Z72.5 High-risk sexual behaviour	0.473	0.527
Z72.4 Inappropriate diet and eating habits	0.473	0.527
Z72.3 Lack of physical exercise	0.473	0.527
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.473	0.527
Z75 Problems related to medical facilities and other health care	0.472	0.528
S10-S19 Injuries to the neck	0.471	0.529
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.471	0.529
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.471	0.529
Z76 Persons encountering health services in other circumstances	0.471	0.529
Z70 Counselling related to sexual attitude, behaviour and orientation	0.471	0.529
B35-B49 Mycoses	0.471	0.529
Q21.1 Atrial septal defect	0.462	0.538
Chapter XXII Codes for special purposes	0.460	0.540
Z33 Pregnant state, incidental	0.458	0.542
Q80-Q89 Other congenital malformations	0.456	0.543
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.456	0.543
Z65 Problems related to other psychosocial circumstances	0.456	0.544
Z64 Problems related to certain psychosocial circumstances	0.456	0.544
Z62 Other problems related to upbringing	0.456	0.544
Z61 Problems related to negative life events in childhood	0.456	0.544
Z58 Problems related to physical environment	0.456	0.544
Z56 Problems related to employment and unemployment	0.456	0.544
Z55 Problems related to education and literacy	0.456	0.544
R49 Voice disturbances	0.455	0.545
Z36 Antenatal screening	0.455	0.545
O40 Polyhydramnios	0.455	0.545
E04 Other non-toxic goitre	0.453	0.547
S90-S99 Injuries to the ankle and foot	0.453	0.547
O43 Placental disorders	0.453	0.547
O23 Infections of genito-urinary tract in pregnancy	0.452	0.548
Chapter XVI Certain conditions originating in the perinatal period	0.450	0.549
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.450	0.550
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.450	0.550
Z35.1 Supervision of pregnancy with history of abortive outcome	0.449	0.551
B37 Candidiasis	0.449	0.551
Q05 Spina bifida	0.448	0.552
Z35.5 Supervision of elderly primigravida	0.447	0.553
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.446	0.554
Z37 Outcome of delivery	0.446	0.554
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.445	0.555
O34 Maternal care for known or suspected abnormality of pelvic organs	0.445	0.555
Z35.8 Supervision of other high-risk pregnancies	0.444	0.556
O21 Excessive vomiting in pregnancy	0.443	0.557
S70-S79 Injuries to the hip and thigh	0.442	0.558
Z29 Need for other prophylactic measures	0.441	0.559
Z28 Immunisation not carried out	0.441	0.559
Z27 Need for immunisation against combinations of infectious diseases	0.441	0.559
Z26 Need for immunisation against other single infectious diseases	0.441	0.559
Z25 Need for immunisation against other single viral diseases	0.441	0.559
Z24 Need for immunisation against certain single viral diseases	0.441	0.559
Z23 Need for immunisation against single bacterial diseases	0.441	0.559
Z20 Contact with and exposure to communicable diseases	0.441	0.559
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.441	0.559
O45 Premature separation of placenta [abruptio placentae]	0.440	0.560
O44 Placenta praevia	0.440	0.560
O41 Other disorders of amniotic fluid and membranes	0.440	0.560
O35 Maternal care for known or suspected foetal abnormality and damage	0.440	0.560
O33 Maternal care for known or suspected disproportion	0.440	0.560
O31 Complications specific to multiple gestation	0.440	0.560
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.440	0.560
Z35.0 Supervision of pregnancy with history of infertility	0.439	0.560
Q38-Q45 Other congenital malformations of the digestive system	0.438	0.562
R76 Other abnormal immunological findings in serum	0.437	0.563
R20 Disturbances of skin sensation	0.436	0.564
R95-R99 Ill-defined and unknown causes of mortality	0.436	0.564
Chapter VII Diseases of the eye and adnexa	0.436	0.564
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.433	0.567
E20-E35 Disorders of other endocrine glands	0.433	0.567
Z71.1 Person with feared complaint in whom no diagnosis is made	0.433	0.567
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.433	0.567
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.433	0.567
R25 Abnormal involuntary movements	0.432	0.568
Z60.9 Problem related to social environment, unspecified	0.432	0.568
Z60.8 Other problems related to social environment	0.432	0.568
Z60.5 Target of perceived adverse discrimination and persecution	0.432	0.568
Z60.4 Social exclusion and rejection	0.432	0.568
Z60.3 Acculturation difficulty	0.432	0.568
Z60.1 Atypical parenting situation	0.432	0.568
Z60.0 Problems of adjustment to life-cycle transitions	0.432	0.568
O36.3 Maternal care for signs of foetal hypoxia	0.431	0.569
R01 Cardiac murmurs and other cardiac sounds	0.429	0.571
S80-S89 Injuries to the knee and lower leg	0.428	0.572
R41.2 Retrograde amnesia	0.427	0.573
Z63.4 Disappearance and death of family member	0.426	0.574
O46 Antepartum haemorrhage, not elsewhere classified	0.426	0.574
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.426	0.574
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.426	0.574
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.426	0.574
Q35-Q37 Cleft lip and cleft palate	0.426	0.574
Q30-Q34 Congenital malformations of the respiratory system	0.426	0.574
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.426	0.574
W00-W19 Falls	0.426	0.574
T20-T25 Burns and corrosions of external body surface, specified by site	0.425	0.575
Q50-Q56 Congenital malformations of genital organs	0.425	0.575
Z38 Liveborn infants according to place of birth	0.424	0.576
Z32 Pregnancy examination and test	0.424	0.576
Z31 Procreative management	0.424	0.576
H93 Other disorders of ear, not elsewhere classified	0.423	0.577
S60-S69 Injuries to the wrist and hand	0.422	0.578
Z22.9 Carrier of infectious disease, unspecified	0.421	0.578
Z22.8 Carrier of other infectious diseases	0.421	0.578
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.421	0.578
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.421	0.578
Z22.2 Carrier of diphtheria	0.421	0.578
Z22.1 Carrier of other intestinal infectious diseases	0.421	0.578
Z22.0 Carrier of typhoid	0.421	0.578
O36.6 Maternal care for excessive foetal growth	0.421	0.578
E10-E14 Diabetes mellitus	0.421	0.579
O42.2 Premature rupture of membranes, labour delayed by therapy	0.421	0.579
O47.0 False labour before 37 completed weeks of gestation	0.420	0.580
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.420	0.580
Z57.3 Occupational exposure to other air contaminants	0.420	0.580
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.420	0.580
Z39.1 Care and examination of lactating mother	0.420	0.580
H61 Other disorders of external ear	0.419	0.581
Z59.8 Other problems relating to housing and economic circumstances	0.418	0.581
Z39.0 Care and examination immediately after delivery	0.418	0.582
E04.2 Non-toxic multinodular goitre	0.418	0.582
R71 Abnormality of red blood cells	0.418	0.582
O36.0 Maternal care for rhesus isoimmunisation	0.417	0.583
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.417	0.583
Q60-Q64 Congenital malformations of the urinary system	0.417	0.583
H92 Otalgia and effusion of ear	0.416	0.584
R26.0 Ataxic gait	0.416	0.584
O30 Multiple gestation	0.415	0.584
O24 Diabetes mellitus in pregnancy	0.415	0.585
Y86 Sequelae of other accidents	0.414	0.586
H90.5 Sensorineural hearing loss, unspecified	0.414	0.586
B15-B19 Viral hepatitis	0.413	0.587
Q21.0 Ventricular septal defect	0.412	0.588
O36.5 Maternal care for poor foetal growth	0.411	0.589
B37.0 Candidal stomatitis	0.410	0.590
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.409	0.591
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.408	0.591
A80-A89 Viral infections of the central nervous system	0.406	0.594
H80-H83 Diseases of inner ear	0.405	0.594
O20 Haemorrhage in early pregnancy	0.405	0.595
R82 Other abnormal findings in urine	0.404	0.595
Q05.9 Spina bifida, unspecified	0.404	0.596
Z74.9 Problem related to care-provider dependency, unspecified	0.403	0.597
Z74.8 Other problems related to care-provider dependency	0.403	0.597
Z74.3 Need for continuous supervision	0.403	0.597
Z74.2 Need for assistance at home and no other household member able to render care	0.403	0.597
Z74.1 Need for assistance with personal care	0.403	0.597
R27.0 Ataxia, unspecified	0.402	0.598
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.402	0.598
R05 Cough	0.401	0.599
O47.9 False labour, unspecified	0.401	0.599
R41.3 Other amnesia	0.401	0.599
T33-T35 Frostbite	0.401	0.599
T26-T28 Burns and corrosions confined to eye and internal organs	0.401	0.599
T00-T07 Injuries involving multiple body regions	0.401	0.599
S40-S49 Injuries to the shoulder and upper arm	0.399	0.601
R27.8 Other and unspecified lack of coordination	0.398	0.602
Z35.9 Supervision of high-risk pregnancy, unspecified	0.398	0.602
Z35.7 Supervision of high-risk pregnancy due to social problems	0.398	0.602
Z35.6 Supervision of very young primigravida	0.398	0.602
Z35.4 Supervision of pregnancy with grand multiparity	0.398	0.602
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.398	0.602
Z71.3 Dietary counselling and surveillance	0.398	0.602
T79-T79 Certain early complications of trauma	0.396	0.604
Z73 Problems related to life-management difficulty	0.395	0.604
R02 Gangrene, not elsewhere classified	0.396	0.604
R01.1 Cardiac murmur, unspecified	0.395	0.605
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.394	0.606
H94 Other disorders of ear in diseases classified elsewhere	0.394	0.606
E40-E46 Malnutrition	0.390	0.610
Z36.8 Other antenatal screening	0.389	0.611
R45 Symptoms and signs involving emotional state	0.389	0.611
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.389	0.611
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.389	0.611
B37.8 Candidiasis of other sites	0.388	0.611
O29 Complications of anaesthesia during pregnancy	0.388	0.612
O28 Abnormal findings on antenatal screening of mother	0.388	0.612
O22 Venous complications in pregnancy	0.388	0.612
O25 Malnutrition in pregnancy	0.388	0.612
E04.1 Non-toxic single thyroid nodule	0.388	0.612
R72 Abnormality of white blood cells, not elsewhere classified	0.388	0.612
S32 Fracture of lumbar spine and pelvis	0.388	0.612
V80-V89 Other land transport accidents	0.387	0.613
X20-X29 Contact with venomous animals and plants	0.386	0.614
O36.9 Maternal care for foetal problem, unspecified	0.385	0.614
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.385	0.614
O36.4 Maternal care for intra-uterine death	0.385	0.614
O36.2 Maternal care for hydrops foetalis	0.385	0.614
O36.1 Maternal care for other isoimmunisation	0.385	0.614
O32.1 Maternal care for breech presentation	0.385	0.615
R46 Symptoms and signs involving appearance and behaviour	0.385	0.615
R43 Disturbances of smell and taste	0.385	0.615
O15 Eclampsia	0.385	0.615
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.385	0.615
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.385	0.615
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.385	0.615
H74 Other disorders of middle ear and mastoid	0.385	0.615
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.383	0.617
Q28 Other congenital malformations of circulatory system	0.383	0.617
Q27 Other congenital malformations of peripheral vascular system	0.383	0.617
Q26 Congenital malformations of great veins	0.383	0.617
Q25 Congenital malformations of great arteries	0.383	0.617
Q24 Other congenital malformations of heart	0.383	0.617
Q22 Congenital malformations of pulmonary and tricuspid valves	0.383	0.617
Q20 Congenital malformations of cardiac chambers and connexions	0.383	0.617
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.382	0.618
S27 Injury of other and unspecified intrathoracic organs	0.382	0.618
S19 Other and unspecified injuries of neck	0.382	0.618
T84.1 Mechanical complication of internal fixation device of bones of limb	0.381	0.619
O36.8 Maternal care for other specified foetal problems	0.380	0.620
O90 Complications of the puerperium, not elsewhere classified	0.379	0.620
R20.2 Paraesthesia of skin	0.379	0.621
R76.8 Other specified abnormal immunological findings in serum	0.379	0.621
H30-H36 Disorders of choroid and retina	0.379	0.621
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.379	0.621
R26.3 Immobility	0.378	0.622
R26.1 Paralytic gait	0.378	0.622
V10-V19 Pedal cyclist injured in transport accident	0.378	0.622
R41.1 Anterograde amnesia	0.378	0.622
R21 Rash and other nonspecific skin eruption	0.377	0.623
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.377	0.623
S30 Superficial injury of abdomen, lower back and pelvis	0.377	0.623
X60-X84 Intentional self-harm	0.376	0.624
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.375	0.625
O97 Death from sequelae of direct obstetric causes	0.375	0.625
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.375	0.625
O95 Obstetric death of unspecified cause	0.375	0.625
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.375	0.625
X40-X49 Accidental poisoning by and exposure to noxious substances	0.373	0.626
A50-A64 Infections with a predominantly sexual mode of transmission	0.373	0.627
E05 Thyrotoxicosis [hyperthyroidism]	0.373	0.627
S20 Superficial injury of thorax	0.373	0.627
H60 Otitis externa	0.373	0.627
R78 Findings of drugs and other substances, not normally found in blood	0.372	0.628
R77 Other abnormalities of plasma proteins	0.372	0.628
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.372	0.628
H73 Other disorders of tympanic membrane	0.371	0.629
O60-O75 Complications of labour and delivery	0.371	0.629
Y35-Y36 Legal intervention and operations of war	0.370	0.630
Y10-Y34 Event of undetermined intent	0.370	0.630
Y00-Y09 Assault	0.370	0.630
X85-X99 Assault	0.370	0.630
X58-X59 Accidental exposure to other and unspecified factors	0.370	0.630
X50-X57 Overexertion, travel and privation	0.370	0.630
X30-X39 Exposure to forces of nature	0.370	0.630
X10-X19 Contact with heat and hot substances	0.370	0.630
X00-X09 Exposure to smoke, fire and flames	0.370	0.630
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.370	0.630
W75-W84 Other accidental threats to breathing	0.370	0.630
W65-W74 Accidental drowning and submersion	0.370	0.630
W50-W64 Exposure to animate mechanical forces	0.370	0.630
V98-V99 Other and unspecified transport accidents	0.370	0.630
V95-V97 Air and space transport accidents	0.370	0.630
V90-V94 Water transport accidents	0.370	0.630
V70-V79 Bus occupant injured in transport accident	0.370	0.630
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.370	0.630
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.370	0.630
V40-V49 Car occupant injured in transport accident	0.370	0.630
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.370	0.630
V01-V09 Pedestrian injured in transport accident	0.370	0.630
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.370	0.630
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.370	0.630
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.370	0.630
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.370	0.630
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.370	0.630
H90.0 Conductive hearing loss, bilateral	0.370	0.630
T92 Sequelae of injuries of upper limb	0.369	0.630
Z63.9 Problem related to primary support group, unspecified	0.369	0.631
Z63.8 Other specified problems related to primary support group	0.369	0.631
Z63.7 Other stressful life events affecting family and household	0.369	0.631
Z63.6 Dependent relative needing care at home	0.369	0.631
Z63.5 Disruption of family by separation and divorce	0.369	0.631
Z63.3 Absence of family member	0.369	0.631
Z63.2 Inadequate family support	0.369	0.631
Z63.1 Problems in relationship with parents and in-laws	0.369	0.631
Z63.0 Problems in relationship with spouse or partner	0.369	0.631
O48 Prolonged pregnancy	0.368	0.632
S80 Superficial injury of lower leg	0.368	0.632
Y52 Agents primarily affecting the cardiovascular system	0.368	0.632
S22 Fracture of rib(s), sternum and thoracic spine	0.367	0.633
O00-O08 Pregnancy with abortive outcome	0.367	0.633
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.367	0.633
R74 Abnormal serum enzyme levels	0.366	0.634
Z39.2 Routine postpartum follow-up	0.366	0.634
E11 Non-insulin-dependent diabetes mellitus	0.366	0.634
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.365	0.634
Z59.7 Insufficient social insurance and welfare support	0.365	0.634
Z59.6 Low income	0.365	0.634
Z59.5 Extreme poverty	0.365	0.634
Z59.4 Lack of adequate food	0.365	0.634
Z59.3 Problems related to living in residential institution	0.365	0.634
Z59.2 Discord with neighbours, lodgers and landlord	0.365	0.634
Z59.1 Inadequate housing	0.365	0.634
Z59.0 Homelessness	0.365	0.634
Q07 Other congenital malformations of nervous system	0.365	0.635
Q06 Other congenital malformations of spinal cord	0.365	0.635
Q04 Other congenital malformations of brain	0.365	0.635
Q03 Congenital hydrocephalus	0.365	0.635
Q01 Encephalocele	0.365	0.635
Q00 Anencephaly and similar malformations	0.365	0.635
Q02 Microcephaly	0.365	0.635
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.363	0.636
O23.4 Unspecified infection of urinary tract in pregnancy	0.363	0.637
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.362	0.638
Z57.9 Occupational exposure to unspecified risk-factor	0.362	0.638
Z57.8 Occupational exposure to other risk-factors	0.362	0.638
Z57.7 Occupational exposure to vibration	0.362	0.638
Z57.6 Occupational exposure to extreme temperature	0.362	0.638
Z57.5 Occupational exposure to toxic agents in other industries	0.362	0.638
Z57.4 Occupational exposure to toxic agents in agriculture	0.362	0.638
Z57.1 Occupational exposure to radiation	0.362	0.638
Z57.0 Occupational exposure to noise	0.362	0.638
Z71.7 Human immunodeficiency virus [HIV] counselling	0.361	0.639
Z71.6 Tobacco abuse counselling	0.361	0.639
Z71.5 Drug abuse counselling and surveillance	0.361	0.639
Z71.4 Alcohol abuse counselling and surveillance	0.361	0.639
Z71.2 Person consulting for explanation of investigation findings	0.361	0.639
Z71.0 Person consulting on behalf of another person	0.361	0.639
O23.5 Infections of the genital tract in pregnancy	0.361	0.639
E23 Hypofunction and other disorders of pituitary gland	0.361	0.639
W20-W49 Exposure to inanimate mechanical forces	0.360	0.640
B37.3 Candidiasis of vulva and vagina	0.359	0.641
B99-B99 Other infectious diseases	0.359	0.641
B90-B94 Sequelae of infectious and parasitic diseases	0.359	0.641
B85-B89 Pediculosis, acariasis and other infestations	0.359	0.641
B65-B83 Helminthiases	0.359	0.641
B50-B64 Protozoal diseases	0.359	0.641
B20-B24 Human immunodeficiency virus [HIV] disease	0.359	0.641
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.359	0.641
A75-A79 Rickettsioses	0.359	0.641
A70-A74 Other diseases caused by chlamydiae	0.359	0.641
A65-A69 Other spirochaetal diseases	0.359	0.641
A20-A28 Certain zoonotic bacterial diseases	0.359	0.641
A15-A19 Tuberculosis	0.359	0.641
Q21.9 Congenital malformation of cardiac septum, unspecified	0.359	0.641
Q21.8 Other congenital malformations of cardiac septa	0.359	0.641
Q21.4 Aortopulmonary septal defect	0.359	0.641
Q21.3 Tetralogy of Fallot	0.359	0.641
Q21.2 Atrioventricular septal defect	0.359	0.641
Q82 Other congenital malformations of skin	0.358	0.642
E29 Testicular dysfunction	0.358	0.642
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.357	0.642
W10 Fall on and from stairs and steps	0.357	0.643
H62 Disorders of external ear in diseases classified elsewhere	0.357	0.643
R25.8 Other and unspecified abnormal involuntary movements	0.357	0.643
T66-T78 Other and unspecified effects of external causes	0.357	0.643
H69 Other disorders of Eustachian tube	0.356	0.643
S12 Fracture of neck	0.356	0.644
Z37.0 Single live birth	0.356	0.644
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.354	0.646
S37 Injury of urinary and pelvic organs	0.354	0.646
S36 Injury of intra-abdominal organs	0.354	0.646
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.354	0.646
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.354	0.646
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.354	0.646
S31 Open wound of abdomen, lower back and pelvis	0.354	0.646
Y40 Systemic antibiotics	0.353	0.647
R26.2 Difficulty in walking, not elsewhere classified	0.352	0.648
S81 Open wound of lower leg	0.352	0.648
T15-T19 Effects of foreign body entering through natural orifice	0.352	0.648
O80-O84 Delivery	0.351	0.649
Y48 Anaesthetics and therapeutic gases	0.350	0.650
O16 Unspecified maternal hypertension	0.349	0.650
R49.0 Dysphonia	0.349	0.651
Z71.9 Counselling, unspecified	0.349	0.651
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.346	0.654
H72 Perforation of tympanic membrane	0.346	0.654
S50-S59 Injuries to the elbow and forearm	0.346	0.654
O92 Other disorders of breast and lactation associated with childbirth	0.345	0.654
O91 Infections of breast associated with childbirth	0.345	0.654
O89 Complications of anaesthesia during the puerperium	0.345	0.654
O88 Obstetric embolism	0.345	0.654
O87 Venous complications in the puerperium	0.345	0.654
O86 Other puerperal infections	0.345	0.654
O85 Puerperal sepsis	0.345	0.654
O32.9 Maternal care for malpresentation of foetus, unspecified	0.345	0.655
O32.8 Maternal care for other malpresentation of foetus	0.345	0.655
O32.6 Maternal care for compound presentation	0.345	0.655
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.345	0.655
O32.4 Maternal care for high head at term	0.345	0.655
O32.3 Maternal care for face, brow and chin presentation	0.345	0.655
O32.2 Maternal care for transverse and oblique lie	0.345	0.655
O32.0 Maternal care for unstable lie	0.345	0.655
R73 Elevated blood glucose level	0.344	0.655
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.344	0.656
Z57.2 Occupational exposure to dust	0.344	0.656
E27 Other disorders of adrenal gland	0.343	0.656
Y60-Y69 Misadventures to patients during surgical and medical care	0.343	0.657
H61.9 Disorder of external ear, unspecified	0.343	0.657
T94 Sequelae of injuries involving multiple and unspecified body regions	0.343	0.657
S72 Fracture of femur	0.342	0.657
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.343	0.657
E00 Congenital iodine-deficiency syndrome	0.343	0.657
E02 Subclinical iodine-deficiency hypothyroidism	0.343	0.657
T14 Injury of unspecified body region	0.342	0.658
H55-H59 Other disorders of eye and adnexa	0.342	0.658
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.342	0.658
H70 Mastoiditis and related conditions	0.342	0.658
H68 Eustachian salpingitis and obstruction	0.342	0.658
H67 Otitis media in diseases classified elsewhere	0.342	0.658
S29 Other and unspecified injuries of thorax	0.342	0.658
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.342	0.658
S26 Injury of heart	0.342	0.658
S25 Injury of blood vessels of thorax	0.342	0.658
S24 Injury of nerves and spinal cord at thorax level	0.342	0.658
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.342	0.658
S21 Open wound of thorax	0.342	0.658
Q23 Congenital malformations of aortic and mitral valves	0.342	0.658
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.341	0.659
E50-E64 Other nutritional deficiencies	0.341	0.659
S91 Open wound of ankle and foot	0.341	0.659
Z75.1 Person awaiting admission to adequate facility elsewhere	0.340	0.660
R44 Other symptoms and signs involving general sensations and perceptions	0.339	0.661
H65 Nonsuppurative otitis media	0.339	0.661
Z75.9 Unspecified problem related to medical facilities and other health care	0.339	0.661
Z75.8 Other problems related to medical facilities and other health care	0.339	0.661
Z75.5 Holiday relief care	0.339	0.661
Z75.4 Unavailability and inaccessibility of other helping agencies	0.339	0.661
Z75.3 Unavailability and inaccessibility of health-care facilities	0.339	0.661
Z75.2 Other waiting period for investigation and treatment	0.339	0.661
Z75.0 Medical services not available in home	0.339	0.661
B35 Dermatophytosis	0.339	0.661
S70 Superficial injury of hip and thigh	0.339	0.661
A87 Viral meningitis	0.338	0.661
T85 Complications of other internal prosthetic devices, implants and grafts	0.338	0.662
S17 Crushing injury of neck	0.338	0.662
S15 Injury of blood vessels at neck level	0.338	0.662
S14 Injury of nerves and spinal cord at neck level	0.338	0.662
S11 Open wound of neck	0.338	0.662
S10 Superficial injury of neck	0.338	0.662
S18 Traumatic amputation at neck level	0.338	0.662
S16 Injury of muscle and tendon at neck level	0.338	0.662
Z34 Supervision of normal pregnancy	0.338	0.662
R81 Glycosuria	0.338	0.662

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations