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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1592404
log Bayes Factor = 42.0859
Chromosome 6   position 29,358,676  (GRCh37) Explore rs1592404 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.005 0.995
E10-E14 Diabetes mellitus
0.000 0.018 0.982
E10.1 With ketoacidosis
0.000 0.026 0.974
E10.2 With renal complications
0.000 0.039 0.961
E13 Other specified diabetes mellitus
0.000 0.041 0.959
E13.9 Without complications
0.000 0.057 0.943
E10.4 With neurological complications
0.000 0.095 0.905
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.156 0.844
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.164 0.836
E16 Other disorders of pancreatic internal secretion
0.000 0.170 0.830
E16.2 Hypoglycaemia, unspecified
0.000 0.178 0.822
E10.6 With other specified complications
0.000 0.181 0.819
E10.5 With peripheral circulatory complications
0.000 0.207 0.793
E14 Unspecified diabetes mellitus
0.000 0.213 0.787
E10.0 With coma
0.000 0.228 0.772
E00-E07 Disorders of thyroid gland
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E16.1 Other hypoglycaemia
0.000 0.285 0.715
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.287 0.713
E12 Malnutrition-related diabetes mellitus
0.000 0.296 0.704
E05.9 Thyrotoxicosis, unspecified
0.000 0.298 0.702
E13.8 With unspecified complications
0.000 0.312 0.687
E13.7 With multiple complications
0.000 0.312 0.687
E13.6 With other specified complications
0.000 0.312 0.687
E13.5 With peripheral circulatory complications
0.000 0.312 0.687
E13.4 With neurological complications
0.000 0.312 0.687
E13.3 With ophthalmic complications
0.000 0.312 0.687
E13.2 With renal complications
0.000 0.312 0.687
E13.1 With ketoacidosis
0.000 0.312 0.687
E13.0 With coma
0.000 0.312 0.687
E20-E35 Disorders of other endocrine glands
0.000 0.317 0.683
E10.8 With unspecified complications
0.000 0.353 0.647
E50-E64 Other nutritional deficiencies
0.000 0.365 0.635
E23 Hypofunction and other disorders of pituitary gland
0.000 0.368 0.632
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.370 0.630
E05.8 Other thyrotoxicosis
0.000 0.380 0.620
E14.9 Without complications
0.000 0.383 0.617
E15 Nondiabetic hypoglycaemic coma
0.000 0.401 0.599
E14.2 Withrenal complications
0.000 0.402 0.598
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.405 0.595
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.405 0.595
E16.4 Abnormal secretion of gastrin
0.000 0.405 0.595
E16.3 Increased secretion of glucagon
0.000 0.405 0.595
E14.4 With neurological complications
0.000 0.407 0.592
E23.0 Hypopituitarism
0.000 0.420 0.580
E14.8 With unspecified complications
0.000 0.423 0.577
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.426 0.573
E40-E46 Malnutrition
0.000 0.428 0.572
E14.1 With ketoacidosis
0.000 0.433 0.567
E14.7 With multiple complications
0.000 0.436 0.564
E14.6 With other specified complications
0.000 0.436 0.564
E14.5 With peripheral circulatory complications
0.000 0.436 0.564
E14.0 With coma
0.000 0.436 0.564
E24 Cushing's syndrome
0.000 0.440 0.560
E20 Hypoparathyroidism
0.000 0.451 0.549
E23.2 Diabetes insipidus
0.000 0.458 0.542
E55 Vitamin D deficiency
0.000 0.460 0.540
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.462 0.538
E11 Non-insulin-dependent diabetes mellitus
0.000 0.471 0.529
E22 Hyperfunction of pituitary gland
0.000 0.479 0.521
E29 Testicular dysfunction
0.000 0.480 0.520
E14.3 With ophthalmic complications
0.000 0.482 0.518
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.483 0.517
E00 Congenital iodine-deficiency syndrome
0.000 0.483 0.517
E05.5 Thyroid crisis or storm
0.000 0.489 0.511
E05.4 Thyrotoxicosis factitia
0.000 0.489 0.511
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.489 0.511
E12.9 Without complications
0.000 0.495 0.505
E12.8 With unspecified complications
0.000 0.495 0.505
E12.7 With multiple complications
0.000 0.495 0.505
E12.6 With other specified complications
0.000 0.495 0.505
E12.5 With peripheral circulatory complications
0.000 0.495 0.505
E12.4 With neurological complications
0.000 0.495 0.505
E12.3 With ophthalmic complications
0.000 0.495 0.505
E12.2 With renal complications
0.000 0.495 0.505
E12.1 With ketoacidosis
0.000 0.495 0.505
E12.0 With coma
0.000 0.495 0.505
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.510 0.490
E32 Diseases of thymus
0.000 0.510 0.490
E30 Disorders of puberty, not elsewhere classified
0.000 0.510 0.490
E25 Adrenogenital disorders
0.000 0.510 0.490
E27 Other disorders of adrenal gland
0.000 0.528 0.472
E55.9 Vitamin D deficiency, unspecified
0.000 0.529 0.471
E56 Other vitamin deficiencies
0.000 0.533 0.467
E23.7 Disorder of pituitary gland, unspecified
0.000 0.537 0.463
E28 Ovarian dysfunction
0.000 0.538 0.462
E53 Deficiency of other B group vitamins
0.000 0.540 0.460
E07 Other disorders of thyroid
0.000 0.540 0.459
E24.9 Cushing's syndrome, unspecified
0.000 0.541 0.459
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.544 0.456
E63 Other nutritional deficiencies
0.000 0.544 0.456
E51 Thiamine deficiency
0.000 0.544 0.456
E50 Vitamin A deficiency
0.000 0.544 0.456
E60 Dietary zinc deficiency
0.000 0.544 0.456
E59 Dietary selenium deficiency
0.000 0.544 0.456
E54 Ascorbic acid deficiency
0.000 0.544 0.456
E52 Niacin deficiency [pellagra]
0.000 0.544 0.456
E11.2 With renal complications
0.000 0.545 0.455
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.547 0.453
E23.1 Drug-induced hypopituitarism
0.000 0.547 0.453
E20.9 Hypoparathyroidism, unspecified
0.000 0.548 0.452
E11.6 With other specified complications
0.000 0.550 0.450
E31 Polyglandular dysfunction
0.000 0.558 0.441
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.571 0.429
E11.0 With coma
0.000 0.580 0.420
E24.2 Drug-induced Cushing's syndrome
0.000 0.580 0.419
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.590 0.410
E45 Retarded development following protein-energy malnutrition
0.000 0.590 0.410
E43 Unspecified severe protein-energy malnutrition
0.000 0.590 0.410
E42 Marasmic kwashiorkor
0.000 0.590 0.410
E41 Nutritional marasmus
0.000 0.590 0.410
E40 Kwashiorkor
0.000 0.590 0.410
E26 Hyperaldosteronism
0.000 0.591 0.409
E22.0 Acromegaly and pituitary gigantism
0.000 0.591 0.409
E53.9 Vitamin B deficiency, unspecified
0.000 0.592 0.408
E61 Deficiency of other nutrient elements
0.000 0.596 0.404
E27.1 Primary adrenocortical insufficiency
0.000 0.597 0.403
E29.1 Testicular hypofunction
0.000 0.598 0.402
E24.8 Other Cushing's syndrome
0.000 0.599 0.401
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.599 0.401
E24.3 Ectopic ACTH syndrome
0.000 0.599 0.401
E24.1 Nelson's syndrome
0.000 0.599 0.401
E24.0 Pituitary-dependent Cushing's disease
0.000 0.599 0.401
E34 Other endocrine disorders
0.000 0.601 0.399
E06 Thyroiditis
0.000 0.601 0.398
E58 Dietary calcium deficiency
0.000 0.604 0.396
E20.8 Other hypoparathyroidism
0.000 0.606 0.393
E20.1 Pseudohypoparathyroidism
0.000 0.606 0.393
E20.0 Idiopathic hypoparathyroidism
0.000 0.606 0.393
E11.1 With ketoacidosis
0.000 0.607 0.393
E55.0 Rickets, active
0.000 0.613 0.387
E11.8 With unspecified complications
0.000 0.613 0.387
E11.7 With multiple complications
0.000 0.621 0.379
E46 Unspecified protein-energy malnutrition
0.000 0.624 0.376
E22.1 Hyperprolactinaemia
0.000 0.626 0.374
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.626 0.374
E22.8 Other hyperfunction of pituitary gland
0.000 0.626 0.374
E29.9 Testicular dysfunction, unspecified
0.000 0.627 0.373
E29.8 Other testicular dysfunction
0.000 0.627 0.373
E29.0 Testicular hyperfunction
0.000 0.627 0.373
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.629 0.370
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.629 0.370
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.629 0.370
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.629 0.370
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.629 0.370
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.629 0.370
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.629 0.370
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.629 0.370
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.632 0.368
K90 Intestinal malabsorption
0.000 0.633 0.367
E23.6 Other disorders of pituitary gland
0.000 0.639 0.360
E28.3 Primary ovarian failure
0.000 0.646 0.353
E25.9 Adrenogenital disorder, unspecified
0.000 0.648 0.351
E25.8 Other adrenogenital disorders
0.000 0.648 0.351
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.648 0.351
E30.9 Disorder of puberty, unspecified
0.000 0.648 0.351
E30.8 Other disorders of puberty
0.000 0.648 0.351
E30.1 Precocious puberty
0.000 0.648 0.351
E30.0 Delayed puberty
0.000 0.648 0.351
E32.9 Disease of thymus, unspecified
0.000 0.648 0.351
E32.8 Other diseases of thymus
0.000 0.648 0.351
E32.1 Abscess of thymus
0.000 0.648 0.351
E32.0 Persistent hyperplasia of thymus
0.000 0.648 0.351
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.648 0.351
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.648 0.351
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.648 0.351
E11.5 With peripheral circulatory complications
0.000 0.651 0.349
E07.8 Other specified disorders of thyroid
0.000 0.653 0.347
E56.1 Deficiency of vitamin K
0.000 0.654 0.346
E27.5 Adrenomedullary hyperfunction
0.000 0.661 0.338
E27.0 Other adrenocortical overactivity
0.000 0.661 0.338
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.663 0.337
E27.9 Disorder of adrenal gland, unspecified
0.000 0.664 0.336
E56.9 Vitamin deficiency, unspecified
0.000 0.665 0.335
E56.8 Deficiency of other vitamins
0.000 0.665 0.335
E56.0 Deficiency of vitamin E
0.000 0.665 0.335
E27.8 Other specified disorders of adrenal gland
0.000 0.667 0.333
E28.9 Ovarian dysfunction, unspecified
0.000 0.668 0.331
E28.8 Other ovarian dysfunction
0.000 0.668 0.331
E28.1 Androgen excess
0.000 0.668 0.331
E28.0 Oestrogen excess
0.000 0.668 0.331
E53.1 Pyridoxine deficiency
0.000 0.670 0.330
E53.0 Riboflavin deficiency
0.000 0.670 0.330
E07.1 Dyshormogenetic goitre
0.000 0.670 0.329
E07.0 Hypersecretion of calcitonin
0.000 0.670 0.329
E50.9 Vitamin A deficiency, unspecified
0.000 0.673 0.327
E50.8 Other manifestations of vitamin A deficiency
0.000 0.673 0.327
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.673 0.327
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.673 0.327
E50.5 Vitamin A deficiency with night blindness
0.000 0.673 0.327
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.673 0.327
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.673 0.327
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.673 0.327
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.673 0.327
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.673 0.327
E51.9 Thiamine deficiency, unspecified
0.000 0.673 0.327
E51.8 Other manifestations of thiamine deficiency
0.000 0.673 0.327
E51.2 Wernicke's encephalopathy
0.000 0.673 0.327
E51.1 Beriberi
0.000 0.673 0.327
E63.9 Nutritional deficiency, unspecified
0.000 0.673 0.327
E63.8 Other specified nutritional deficiencies
0.000 0.673 0.327
E63.1 Imbalance of constituents of food intake
0.000 0.673 0.327
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.673 0.327
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.673 0.327
E64.8 Sequelae of other nutritional deficiencies
0.000 0.673 0.327
E64.3 Sequelae of rickets
0.000 0.673 0.327
E64.2 Sequelae of vitamin C deficiency
0.000 0.673 0.327
E64.1 Sequelae of vitamin A deficiency
0.000 0.673 0.327
E64.0 Sequelae of protein-energy malnutrition
0.000 0.673 0.327
E06.9 Thyroiditis, unspecified
0.000 0.677 0.323
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.677 0.322
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.682 0.318
E31.9 Polyglandular dysfunction, unspecified
0.000 0.683 0.316
E31.8 Other polyglandular dysfunction
0.000 0.683 0.316
E31.1 Polyglandular hyperfunction
0.000 0.683 0.316
E03 Other hypothyroidism
0.000 0.689 0.311
E83 Disorders of mineral metabolism
0.310 0.690 0.000
E11.4 With neurological complications
0.000 0.702 0.298
E44.1 Mild protein-energy malnutrition
0.000 0.706 0.294
E44.0 Moderate protein-energy malnutrition
0.000 0.706 0.294
E26.9 Hyperaldosteronism, unspecified
0.000 0.706 0.293
E26.8 Other hyperaldosteronism
0.000 0.706 0.293
E26.1 Secondary hyperaldosteronism
0.000 0.706 0.293
E34.8 Other specified endocrine disorders
0.000 0.709 0.290
E61.9 Deficiency of nutrient element, unspecified
0.000 0.710 0.290
E61.8 Deficiency of other specified nutrient elements
0.000 0.710 0.290
E61.7 Deficiency of multiple nutrient elements
0.000 0.710 0.290
E61.6 Vanadium deficiency
0.000 0.710 0.290
E61.5 Molybdenum deficiency
0.000 0.710 0.290
E61.4 Chromium deficiency
0.000 0.710 0.290
E61.3 Manganese deficiency
0.000 0.710 0.290
E61.0 Copper deficiency
0.000 0.710 0.290
E34.5 Androgen resistance syndrome
0.000 0.714 0.286
E34.4 Constitutional tall stature
0.000 0.714 0.286
E34.3 Short stature, not elsewhere classified
0.000 0.714 0.286
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.714 0.286
E34.1 Other hypersecretion of intestinal hormones
0.000 0.714 0.286
E06.4 Drug-induced thyroiditis
0.000 0.714 0.286
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.714 0.286
E06.1 Subacute thyroiditis
0.000 0.714 0.286
E06.0 Acute thyroiditis
0.000 0.714 0.286
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.720 0.280
E28.2 Polycystic ovarian syndrome
0.000 0.728 0.272
E61.1 Iron deficiency
0.000 0.729 0.271
E65-E68 Obesity and other hyperalimentation
0.000 0.730 0.270
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.732 0.268
E31.0 Autoimmune polyglandular failure
0.000 0.732 0.268
E34.9 Endocrine disorder, unspecified
0.000 0.732 0.268
K90.3 Pancreatic steatorrhoea
0.000 0.737 0.263
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.737 0.263
K90.1 Tropical sprue
0.000 0.737 0.263
E61.2 Magnesium deficiency
0.000 0.738 0.261
E83.3 Disorders of phosphorus metabolism
0.254 0.746 0.000
K90.8 Other intestinal malabsorption
0.000 0.756 0.244
E07.9 Disorder of thyroid, unspecified
0.000 0.757 0.243
E03.8 Other specified hypothyroidism
0.000 0.761 0.239
E27.2 Addisonian crisis
0.000 0.763 0.236
K90.9 Intestinal malabsorption, unspecified
0.000 0.770 0.230
E06.5 Other chronic thyroiditis
0.000 0.776 0.223
E03.5 Myxoedema coma
0.000 0.777 0.223
E03.4 Atrophy of thyroid (acquired)
0.000 0.777 0.223
E03.3 Postinfectious hypothyroidism
0.000 0.777 0.223
E03.1 Congenital hypothyroidism without goitre
0.000 0.777 0.223
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.777 0.223
E83.9 Disorder of mineral metabolism, unspecified
0.222 0.777 0.000
E83.8 Other disorders of mineral metabolism
0.222 0.777 0.000
E83.2 Disorders of zinc metabolism
0.222 0.777 0.000
E83.0 Disorders of copper metabolism
0.222 0.777 0.000
E34.0 Carcinoid syndrome
0.000 0.783 0.216
E83.4 Disorders of magnesium metabolism
0.216 0.784 0.000
E26.0 Primary hyperaldosteronism
0.000 0.787 0.213
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.790 0.210
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.794 0.206
E67 Other hyperalimentation
0.000 0.806 0.194
E68 Sequelae of hyperalimentation
0.000 0.806 0.194
E21.4 Other specified disorders of parathyroid gland
0.000 0.807 0.192
E21.2 Other hyperparathyroidism
0.000 0.807 0.192
E06.3 Autoimmune thyroiditis
0.000 0.822 0.178
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.828 0.172
E21.3 Hyperparathyroidism, unspecified
0.000 0.832 0.168
E04 Other non-toxic goitre
0.001 0.854 0.145
E53.8 Deficiency of other specified B group vitamins
0.000 0.856 0.144
E65 Localised adiposity
0.000 0.859 0.140
E67.8 Other specified hyperalimentation
0.000 0.861 0.139
E67.3 Hypervitaminosis D
0.000 0.861 0.139
E67.2 Megavitamin-B6 syndrome
0.000 0.861 0.139
E67.1 Hypercarotenaemia
0.000 0.861 0.139
E67.0 Hypervitaminosis A
0.000 0.861 0.139
E11.3 With ophthalmic complications
0.000 0.865 0.135
E04.9 Non-toxic goitre, unspecified
0.000 0.875 0.125
E11.9 Without complications
0.000 0.883 0.117
E04.8 Other specified non-toxic goitre
0.001 0.895 0.104
E83.5 Disorders of calcium metabolism
0.100 0.900 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.937 0.062
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.055 0.945 0.000
E21.0 Primary hyperparathyroidism
0.000 0.947 0.053
E66 Obesity
0.000 0.973 0.027
I83 Varicose veins of lower extremities
0.024 0.976 0.000
K90-K93 Other diseases of the digestive system
0.000 0.978 0.021
K51 Ulcerative colitis
0.021 0.979 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.021 0.979 0.000
K51.4 Pseudopolyposis of colon
0.020 0.980 0.000
K51.9 Ulcerative colitis, unspecified
0.020 0.980 0.000
E66.1 Drug-induced obesity
0.000 0.980 0.019
V18.0 Driver injured in nontraffic accident
0.019 0.981 0.000
K51.2 Ulcerative (chronic) proctitis
0.019 0.981 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.018 0.982 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.018 0.982 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.017 0.983 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.983 0.017
K51.5 Mucosal proctocolitis
0.017 0.983 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.984 0.015
H54.0 Blindness, both eyes
0.000 0.984 0.016
E66.0 Obesity due to excess calories
0.000 0.984 0.016
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.984 0.015
K51.1 Ulcerative (chronic) ileocolitis
0.015 0.984 0.000
H54 Blindness and low vision
0.000 0.986 0.014
H54.9 Unspecified visual impairment (binocular)
0.000 0.986 0.014
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.014
I83.0 Varicose veins of lower extremities with ulcer
0.014 0.986 0.000
F45.8 Other somatoform disorders
0.000 0.987 0.013
J38.4 Oedema of larynx
0.013 0.987 0.000
K51.8 Other ulcerative colitis
0.013 0.987 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.987 0.013
J38.7 Other diseases of larynx
0.012 0.988 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.988 0.012
E04.2 Non-toxic multinodular goitre
0.001 0.988 0.011
H54.5 Low vision, one eye
0.000 0.988 0.012
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.012 0.988 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.988 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.988 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.988 0.011
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.988 0.012
E70-E90 Metabolic disorders
0.004 0.989 0.008
J38.3 Other diseases of vocal cords
0.011 0.989 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.989 0.011
H54.7 Unspecified visual loss
0.000 0.989 0.011
H54.3 Unqualified visual loss, both eyes
0.000 0.989 0.010
V18 Pedal cyclist injured in noncollision transport accident
0.011 0.989 0.000
J38.2 Nodules of vocal cords
0.010 0.990 0.000
H54.2 Low vision, both eyes
0.000 0.990 0.010
N18.5 Chronic kidney disease, stage 5
0.000 0.990 0.010
J38.5 Laryngeal spasm
0.010 0.990 0.000
H54.4 Blindness, one eye
0.000 0.991 0.009
H54.1 Blindness, one eye, low vision, other eye
0.000 0.991 0.009
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.009 0.991 0.000
E73 Lactose intolerance
0.002 0.991 0.007
N18 Chronic renal failure
0.000 0.991 0.009
E79 Disorders of purine and pyrimidine metabolism
0.002 0.991 0.006
E74 Other disorders of carbohydrate metabolism
0.002 0.992 0.006
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.992 0.006
E77 Disorders of glycoprotein metabolism
0.003 0.992 0.006
E76 Disorders of glycosaminoglycan metabolism
0.003 0.992 0.006
E72 Other disorders of amino-acid metabolism
0.003 0.992 0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.992 0.006
E70 Disorders of aromatic amino-acid metabolism
0.003 0.992 0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.992 0.006
J38.1 Polyp of vocal cord and larynx
0.008 0.992 0.000
V18.5 Passenger injured in traffic accident
0.008 0.992 0.000
E84 Cystic fibrosis
0.003 0.992 0.005
V18.9 Unspecified pedal cyclist injured in traffic accident
0.008 0.992 0.000
V18.4 Driver injured in traffic accident
0.008 0.992 0.000
V18.1 Passenger injured in nontraffic accident
0.008 0.992 0.000
F45 Somatoform disorders
0.000 0.992 0.008
E85 Amyloidosis
0.002 0.992 0.006
N18.0 End-stage renal disease
0.000 0.992 0.008
J38.6 Stenosis of larynx
0.007 0.993 0.000
M79.0 Rheumatism, unspecified
0.000 0.993 0.007
C43.5 Malignant melanoma of trunk
0.000 0.993 0.007
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.007 0.993 0.000
V18.3 Person injured while boarding or alighting
0.007 0.993 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.993 0.006
M79.08 Rheumatism, unspecified (Other)
0.000 0.993 0.007
E66.8 Other obesity
0.000 0.993 0.007
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.993 0.007
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.993 0.005
E73.8 Other lactose intolerance
0.002 0.993 0.005
E73.1 Secondary lactase deficiency
0.002 0.993 0.005
E73.0 Congenital lactase deficiency
0.002 0.993 0.005
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.994 0.005
F45.9 Somatoform disorder, unspecified
0.000 0.994 0.006
E75.5 Other lipid storage disorders
0.002 0.994 0.005
N18.1 Chronic kidney disease, stage 1
0.000 0.994 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.994 0.005
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.994 0.005
E79.1 Lesch-Nyhan syndrome
0.002 0.994 0.005
J35.8 Other chronic diseases of tonsils and adenoids
0.006 0.994 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.994 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.994 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.994 0.005
E74.2 Disorders of galactose metabolism
0.002 0.994 0.005
E74.1 Disorders of fructose metabolism
0.002 0.994 0.005
E74.0 Glycogen storage disease
0.002 0.994 0.005
E75.6 Lipid storage disorder, unspecified
0.002 0.994 0.004
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.994 0.004
E75.3 Sphingolipidosis, unspecified
0.002 0.994 0.004
E75.2 Other sphingolipidosis
0.002 0.994 0.004
E75.1 Other gangliosidosis
0.002 0.994 0.004
E75.0 GM2 gangliosidosis
0.002 0.994 0.004
N18.9 Chronic renal failure, unspecified
0.000 0.994 0.006
K04.5 Chronic apical periodontitis
0.006 0.994 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.994 0.006
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.994 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.994 0.004
E70.3 Albinism
0.002 0.994 0.004
E70.2 Disorders of tyrosine metabolism
0.002 0.994 0.004
E70.1 Other hyperphenylalaninaemias
0.002 0.994 0.004
E70.0 Classical phenylketonuria
0.002 0.994 0.004
E71.3 Disorders of fatty-acid metabolism
0.002 0.994 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.994 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.994 0.004
E71.0 Maple-syrup-urine disease
0.002 0.994 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.994 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.994 0.004
E72.5 Disorders of glycine metabolism
0.002 0.994 0.004
E72.4 Disorders of ornithine metabolism
0.002 0.994 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.994 0.004
E72.2 Disorders of urea cycle metabolism
0.002 0.994 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.994 0.004
E72.0 Disorders of amino-acid transport
0.002 0.994 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.994 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.994 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.994 0.004
E76.2 Other mucopolysaccharidoses
0.002 0.994 0.004
E76.1 Mucopolysaccharidosis, type II
0.002 0.994 0.004
E76.0 Mucopolysaccharidosis, type I
0.002 0.994 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.994 0.004
E77.8 Other disorders of glycoprotein metabolism
0.002 0.994 0.004
E77.1 Defects in glycoprotein degradation
0.002 0.994 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.994 0.004
C50.8 Overlapping lesion of breast
0.000 0.994 0.006
D47.4 Osteomyelofibrosis
0.000 0.994 0.006
F45.0 Somatisation disorder
0.000 0.994 0.006
E88 Other metabolic disorders
0.002 0.994 0.004
E84.8 Cystic fibrosis with other manifestations
0.002 0.994 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.994 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.994 0.004
S42.10 Fracture of scapula (closed)
0.000 0.994 0.006
F45.2 Hypochondriacal disorder
0.000 0.994 0.006
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.006 0.994 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.006 0.994 0.000
C50.3 Lower-inner quadrant of breast
0.000 0.994 0.006
D47.2 Monoclonal gammopathy
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.002 0.994 0.004
F45.1 Undifferentiated somatoform disorder
0.000 0.994 0.006
E85.8 Other amyloidosis
0.002 0.994 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.994 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.994 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.994 0.004
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.994 0.006
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.994 0.006
N18.8 Other chronic renal failure
0.000 0.994 0.006
E85.4 Organ-limited amyloidosis
0.001 0.994 0.005
F45.3 Somatoform autonomic dysfunction
0.000 0.994 0.006
E85.3 Secondary systemic amyloidosis
0.001 0.994 0.004
F45.4 Persistent somatoform pain disorder
0.000 0.994 0.005
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.994 0.005
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.994 0.005
M79.04 Rheumatism, unspecified (Hand)
0.000 0.994 0.005
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.994 0.005
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.994 0.005
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.994 0.006
N18.2 Chronic kidney disease, stage 2
0.000 0.994 0.005
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.994 0.006
V10-V19 Pedal cyclist injured in transport accident
0.005 0.995 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.995 0.003
F41.1 Generalised anxiety disorder
0.000 0.995 0.005
K50-K52 Noninfective enteritis and colitis
0.005 0.995 0.000
E85.9 Amyloidosis, unspecified
0.002 0.995 0.004
H53.2 Diplopia
0.000 0.995 0.005
H53-H54 Visual disturbances and blindness
0.000 0.995 0.005
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.995 0.003
E88.9 Metabolic disorder, unspecified
0.002 0.995 0.003
V19 Pedal cyclist injured in other and unspecified transport accidents
0.005 0.995 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.995 0.005
C50 Malignant neoplasm of breast
0.000 0.995 0.005
N48.4 Impotence of organic origin
0.005 0.995 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.995 0.005
M79.06 Rheumatism, unspecified (Lower leg)
0.000 0.995 0.004
E88.2 Lipomatosis, not elsewhere classified
0.001 0.995 0.003
E88.3 Tumour lysis syndrome
0.002 0.996 0.003
J38.0 Paralysis of vocal cords and larynx
0.004 0.996 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.004 0.996 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.004 0.996 0.000
K50 Crohn's disease [regional enteritis]
0.004 0.996 0.000
E88.8 Other specified metabolic disorders
0.002 0.996 0.002
Z99.1 Dependence on respirator
0.000 0.996 0.004
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.996 0.004
C50.1 Central portion of breast
0.000 0.996 0.004
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.996 0.004
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.996 0.004
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.996 0.004
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident
0.004 0.996 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.004 0.996 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.004 0.996 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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