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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1610585
log Bayes Factor = 36.9144
Chromosome 6   position 29,675,676  (GRCh37) Explore rs1610585 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
L40 Psoriasis
0.000 0.005 0.995
L40.5 Arthropathic psoriasis
0.000 0.007 0.993
E10.1 With ketoacidosis
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.026 0.974
E10.0 With coma
0.000 0.120 0.880
G35 Multiple sclerosis
0.849 0.151 0.000
L40.8 Other psoriasis
0.000 0.203 0.797
E10.2 With renal complications
0.000 0.221 0.779
L40.0 Psoriasis vulgaris
0.000 0.231 0.769
E10.6 With other specified complications
0.000 0.271 0.729
L40.2 Acrodermatitis continua
0.000 0.287 0.713
L40.1 Generalised pustular psoriasis
0.000 0.287 0.713
E10.8 With unspecified complications
0.000 0.320 0.680
E10.7 With multiple complications
0.000 0.345 0.655
L40.3 Pustulosis palmaris et plantaris
0.000 0.359 0.641
L40.4 Guttate psoriasis
0.000 0.360 0.640
E10.4 With neurological complications
0.000 0.384 0.616
E10.5 With peripheral circulatory complications
0.000 0.401 0.599
K90 Intestinal malabsorption
0.000 0.519 0.481
G35-G37 Demyelinating diseases of the central nervous system
0.445 0.555 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.604 0.396
G37 Other demyelinating diseases of central nervous system
0.353 0.647 0.000
K90.8 Other intestinal malabsorption
0.000 0.652 0.347
K90.3 Pancreatic steatorrhoea
0.000 0.655 0.345
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.655 0.345
K90.1 Tropical sprue
0.000 0.655 0.345
G36 Other acute disseminated demyelination
0.332 0.668 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.306 0.694 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.705 0.295
G37.8 Other specified demyelinating diseases of central nervous system
0.258 0.742 0.000
E10-E14 Diabetes mellitus
0.000 0.743 0.257
G37.5 Concentric sclerosis [Balo]
0.253 0.746 0.000
G37.4 Subacute necrotising myelitis
0.253 0.746 0.000
G37.2 Central pontine myelinolysis
0.253 0.746 0.000
G37.1 Central demyelination of corpus callosum
0.253 0.746 0.000
G37.0 Diffuse sclerosis
0.253 0.746 0.000
G36.0 Neuromyelitis optica [Devic]
0.251 0.748 0.000
E83 Disorders of mineral metabolism
0.245 0.755 0.000
L40-L45 Papulosquamous disorders
0.011 0.760 0.229
G36.9 Acute disseminated demyelination, unspecified
0.238 0.761 0.000
G36.8 Other specified acute disseminated demyelination
0.238 0.761 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.238 0.761 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.221 0.779 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.208 0.792 0.000
E83.3 Disorders of phosphorus metabolism
0.208 0.792 0.000
E14 Unspecified diabetes mellitus
0.000 0.799 0.201
M06.9 Rheumatoid arthritis, unspecified
0.000 0.799 0.201
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.802 0.198
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.804 0.196
I71 Aortic aneurysm and dissection
0.185 0.815 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.816 0.184
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.820 0.180
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.822 0.178
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.824 0.176
E83.9 Disorder of mineral metabolism, unspecified
0.176 0.824 0.000
E83.8 Other disorders of mineral metabolism
0.176 0.824 0.000
E83.2 Disorders of zinc metabolism
0.176 0.824 0.000
E83.0 Disorders of copper metabolism
0.176 0.824 0.000
L44 Other papulosquamous disorders
0.008 0.828 0.164
L41 Parapsoriasis
0.008 0.828 0.164
L45 Papulosquamous disorders in diseases classified elsewhere
0.008 0.828 0.164
E14.3 With ophthalmic complications
0.000 0.829 0.171
I71.3 Abdominal aortic aneurysm, ruptured
0.169 0.831 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.831 0.169
L42 Pityriasis rosea
0.007 0.831 0.161
E13 Other specified diabetes mellitus
0.000 0.835 0.165
E14.4 With neurological complications
0.000 0.836 0.164
I71.0 Dissection of aorta [any part]
0.161 0.839 0.000
E14.5 With peripheral circulatory complications
0.000 0.840 0.160
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.845 0.155
E14.1 With ketoacidosis
0.000 0.853 0.147
E14.7 With multiple complications
0.000 0.855 0.144
E14.2 Withrenal complications
0.000 0.855 0.144
E14.0 With coma
0.000 0.855 0.144
E14.8 With unspecified complications
0.000 0.856 0.144
I71.1 Thoracic aortic aneurysm, ruptured
0.141 0.859 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.135 0.865 0.000
E14.6 With other specified complications
0.000 0.865 0.135
I71.8 Aortic aneurysm of unspecified site, ruptured
0.133 0.867 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.133 0.867 0.000
E12.9 Without complications
0.000 0.868 0.132
E12.8 With unspecified complications
0.000 0.868 0.132
E12.7 With multiple complications
0.000 0.868 0.132
E12.6 With other specified complications
0.000 0.868 0.132
E12.5 With peripheral circulatory complications
0.000 0.868 0.132
E12.4 With neurological complications
0.000 0.868 0.132
E12.3 With ophthalmic complications
0.000 0.868 0.132
E12.2 With renal complications
0.000 0.868 0.132
E12.1 With ketoacidosis
0.000 0.868 0.132
E12.0 With coma
0.000 0.868 0.132
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.126 0.873 0.000
L41.9 Parapsoriasis, unspecified
0.006 0.876 0.118
L41.8 Other parapsoriasis
0.006 0.876 0.118
L41.5 Retiform parapsoriasis
0.006 0.876 0.118
L41.4 Large plaque parapsoriasis
0.006 0.876 0.118
L41.3 Small plaque parapsoriasis
0.006 0.876 0.118
L41.2 Lymphomatoid papulosis
0.006 0.876 0.118
L41.1 Pityriasis lichenoides chronica
0.006 0.876 0.118
L41.0 Pityriasis lichenoides et varioliformis acuta
0.006 0.876 0.118
L44.9 Papulosquamous disorder, unspecified
0.006 0.876 0.118
L44.8 Other specified papulosquamous disorders
0.006 0.876 0.118
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.006 0.876 0.118
L44.3 Lichen ruber moniliformis
0.006 0.876 0.118
L44.2 Lichen striatus
0.006 0.876 0.118
L44.1 Lichen nitidus
0.006 0.876 0.118
L44.0 Pityriasis rubra pilaris
0.006 0.876 0.118
E13.3 With ophthalmic complications
0.000 0.879 0.121
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.880 0.120
E13.8 With unspecified complications
0.000 0.882 0.118
E13.7 With multiple complications
0.000 0.882 0.118
E13.6 With other specified complications
0.000 0.882 0.118
E13.5 With peripheral circulatory complications
0.000 0.882 0.118
E13.4 With neurological complications
0.000 0.882 0.118
E13.2 With renal complications
0.000 0.882 0.118
E13.1 With ketoacidosis
0.000 0.882 0.118
E13.0 With coma
0.000 0.882 0.118
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.883 0.117
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.116 0.884 0.000
L43 Lichen planus
0.036 0.891 0.074
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.893 0.107
E83.5 Disorders of calcium metabolism
0.098 0.902 0.000
E13.9 Without complications
0.000 0.905 0.095
M06 Other rheumatoid arthritis
0.000 0.907 0.093
L43.3 Subacute (active) lichen planus
0.026 0.922 0.053
L43.2 Lichenoid drug reaction
0.026 0.922 0.053
L43.1 Bullous lichen planus
0.026 0.922 0.053
L43.0 Hypertrophic lichen planus
0.026 0.922 0.053
E83.4 Disorders of magnesium metabolism
0.074 0.926 0.000
E89.0 Postprocedural hypothyroidism
0.073 0.927 0.000
M06.3 Rheumatoid nodule
0.000 0.927 0.073
L43.8 Other lichen planus
0.028 0.931 0.042
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.068 0.932 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.933 0.067
M06.2 Rheumatoid bursitis
0.000 0.933 0.067
M06.1 Adult-onset Still's disease
0.000 0.933 0.067
M06.4 Inflammatory polyarthropathy
0.000 0.936 0.064
E14.9 Without complications
0.000 0.937 0.063
L43.9 Lichen planus, unspecified
0.060 0.938 0.002
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.938 0.061
E89.2 Postprocedural hypoparathyroidism
0.061 0.939 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.061 0.939 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.940 0.060
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.941 0.059
N13 Obstructive and reflux uropathy
0.000 0.943 0.057
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.944 0.056
Chapter IV Endocrine, nutritional and metabolic diseases
0.004 0.944 0.052
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.944 0.056
E89.4 Postprocedural ovarian failure
0.054 0.945 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.946 0.054
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.946 0.054
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.946 0.053
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.002 0.946 0.052
E89.1 Postprocedural hypoinsulinaemia
0.053 0.947 0.000
E11.0 With coma
0.000 0.947 0.053
E16 Other disorders of pancreatic internal secretion
0.000 0.948 0.052
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.948 0.052
M06.38 Rheumatoid nodule (Other)
0.000 0.948 0.052
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.948 0.052
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.948 0.052
M06.33 Rheumatoid nodule (Forearm)
0.000 0.948 0.052
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.948 0.052
E70-E90 Metabolic disorders
0.051 0.948 0.001
E11.6 With other specified complications
0.000 0.949 0.051
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.950 0.050
E16.2 Hypoglycaemia, unspecified
0.000 0.950 0.050
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.049 0.951 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.049 0.951 0.000
E89.5 Postprocedural testicular hypofunction
0.049 0.951 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.952 0.048
M06.18 Adult-onset Still's disease (Other)
0.000 0.952 0.048
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.952 0.048
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.952 0.048
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.952 0.048
M06.14 Adult-onset Still's disease (Hand)
0.000 0.952 0.048
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.952 0.048
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.952 0.048
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.952 0.048
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.952 0.048
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.952 0.048
M06.28 Rheumatoid bursitis (Other)
0.000 0.952 0.048
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.952 0.048
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.952 0.048
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.952 0.048
M06.24 Rheumatoid bursitis (Hand)
0.000 0.952 0.048
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.952 0.048
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.952 0.048
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.952 0.048
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.952 0.048
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.952 0.048
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.952 0.048
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.952 0.048
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.952 0.048
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.952 0.048
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.952 0.048
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.952 0.048
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.952 0.048
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.952 0.048
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.952 0.048
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.952 0.048
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.953 0.047
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.953 0.047
M06.0 Seronegative rheumatoid arthritis
0.000 0.953 0.047
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.954 0.046
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.954 0.046
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.954 0.046
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.954 0.046
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.954 0.046
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.954 0.046
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.954 0.046
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.954 0.046
E11.8 With unspecified complications
0.000 0.954 0.046
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.954 0.045
E20-E35 Disorders of other endocrine glands
0.000 0.954 0.045
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.956 0.044
E16.1 Other hypoglycaemia
0.000 0.956 0.044
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.956 0.044
E11.7 With multiple complications
0.000 0.957 0.043
K90-K93 Other diseases of the digestive system
0.000 0.957 0.043
M06.34 Rheumatoid nodule (Hand)
0.000 0.957 0.043
M07.3 Other psoriatic arthropathies
0.000 0.958 0.042
M07 Psoriatic and enteropathic arthropathies
0.000 0.959 0.041
M05-M14 Inflammatory polyarthropathies
0.000 0.959 0.041
E50-E64 Other nutritional deficiencies
0.001 0.960 0.039
E84 Cystic fibrosis
0.039 0.960 0.001
E11.2 With renal complications
0.000 0.960 0.039
E24 Cushing's syndrome
0.000 0.961 0.039
E74 Other disorders of carbohydrate metabolism
0.038 0.961 0.001
E15 Nondiabetic hypoglycaemic coma
0.001 0.961 0.037
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.038 0.961 0.001
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.962 0.038
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.962 0.037
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.962 0.037
E16.4 Abnormal secretion of gastrin
0.000 0.962 0.037
E16.3 Increased secretion of glucagon
0.000 0.962 0.037
E11.4 With neurological complications
0.000 0.962 0.038
E11.1 With ketoacidosis
0.000 0.962 0.038
E77 Disorders of glycoprotein metabolism
0.037 0.962 0.001
E76 Disorders of glycosaminoglycan metabolism
0.037 0.962 0.001
E72 Other disorders of amino-acid metabolism
0.037 0.962 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.037 0.962 0.001
E70 Disorders of aromatic amino-acid metabolism
0.037 0.962 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.037 0.962 0.001
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.963 0.037
E61 Deficiency of other nutrient elements
0.000 0.963 0.037
E28 Ovarian dysfunction
0.000 0.963 0.036
E21.0 Primary hyperparathyroidism
0.000 0.964 0.036
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.964 0.036
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.964 0.035
E79 Disorders of purine and pyrimidine metabolism
0.034 0.965 0.001
E21.4 Other specified disorders of parathyroid gland
0.000 0.965 0.034
E61.1 Iron deficiency
0.000 0.965 0.034
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.966 0.034
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.966 0.034
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.966 0.034
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.966 0.034
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.966 0.034
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.966 0.034
N13.6 Pyonephrosis
0.000 0.966 0.034
E29 Testicular dysfunction
0.000 0.966 0.034
M12 Other specific arthropathies
0.000 0.966 0.034
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.967 0.033
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.967 0.033
E32 Diseases of thymus
0.000 0.967 0.033
E31 Polyglandular dysfunction
0.000 0.967 0.033
E30 Disorders of puberty, not elsewhere classified
0.000 0.967 0.033
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.967 0.033
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.967 0.033
E73 Lactose intolerance
0.031 0.968 0.001
E25 Adrenogenital disorders
0.000 0.968 0.032
E28.2 Polycystic ovarian syndrome
0.000 0.968 0.032
E24.2 Drug-induced Cushing's syndrome
0.000 0.968 0.032
E24.0 Pituitary-dependent Cushing's disease
0.000 0.968 0.032
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.969 0.031
E84.9 Cystic fibrosis, unspecified
0.031 0.969 0.001
E40-E46 Malnutrition
0.003 0.969 0.028
E21.2 Other hyperparathyroidism
0.000 0.969 0.031
E80 Disorders of porphyrin and bilirubin metabolism
0.030 0.969 0.001
M07.38 Other psoriatic arthropathies (Other)
0.000 0.970 0.030
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.970 0.030
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.970 0.030
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.970 0.030
M11 Other crystal arthropathies
0.000 0.970 0.030
M07.5 Arthropathy in ulcerative colitis
0.000 0.970 0.029
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.970 0.029
M07.2 Psoriatic spondylitis
0.000 0.970 0.029
M07.1 Arthritis mutilans
0.000 0.970 0.029
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.970 0.029
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.970 0.029
M07.6 Other enteropathic arthropathies
0.000 0.971 0.029
E74.3 Other disorders of intestinal carbohydrate absorption
0.029 0.971 0.001
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.971 0.028
E63 Other nutritional deficiencies
0.001 0.971 0.028
E56 Other vitamin deficiencies
0.001 0.971 0.028
E50 Vitamin A deficiency
0.001 0.971 0.028
E60 Dietary zinc deficiency
0.001 0.971 0.028
E59 Dietary selenium deficiency
0.001 0.971 0.028
E54 Ascorbic acid deficiency
0.001 0.971 0.028
E52 Niacin deficiency [pellagra]
0.001 0.971 0.028
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.971 0.029
E84.8 Cystic fibrosis with other manifestations
0.028 0.971 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.028 0.971 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.028 0.971 0.001
E61.2 Magnesium deficiency
0.000 0.971 0.029
N13.3 Other and unspecified hydronephrosis
0.000 0.971 0.029
E51 Thiamine deficiency
0.001 0.971 0.028
E75.5 Other lipid storage disorders
0.028 0.971 0.001
E20 Hypoparathyroidism
0.000 0.971 0.028
M08 Juvenile arthritis
0.000 0.971 0.028
E24.9 Cushing's syndrome, unspecified
0.000 0.972 0.028
E24.8 Other Cushing's syndrome
0.000 0.972 0.028
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.972 0.028
E24.3 Ectopic ACTH syndrome
0.000 0.972 0.028
E24.1 Nelson's syndrome
0.000 0.972 0.028
E74.9 Disorder of carbohydrate metabolism, unspecified
0.027 0.972 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.027 0.972 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.027 0.972 0.001
E74.2 Disorders of galactose metabolism
0.027 0.972 0.001
E74.1 Disorders of fructose metabolism
0.027 0.972 0.001
E74.0 Glycogen storage disease
0.027 0.972 0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.972 0.028
E75.6 Lipid storage disorder, unspecified
0.027 0.972 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.027 0.972 0.001
E75.3 Sphingolipidosis, unspecified
0.027 0.972 0.001
E75.2 Other sphingolipidosis
0.027 0.972 0.001
E75.1 Other gangliosidosis
0.027 0.972 0.001
E75.0 GM2 gangliosidosis
0.027 0.972 0.001
E11.5 With peripheral circulatory complications
0.000 0.973 0.027
C73 Malignant neoplasm of thyroid gland
0.027 0.973 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.026 0.973 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.026 0.973 0.001
E70.3 Albinism
0.026 0.973 0.001
E70.2 Disorders of tyrosine metabolism
0.026 0.973 0.001
E70.1 Other hyperphenylalaninaemias
0.026 0.973 0.001
E70.0 Classical phenylketonuria
0.026 0.973 0.001
E71.3 Disorders of fatty-acid metabolism
0.026 0.973 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.026 0.973 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.026 0.973 0.001
E71.0 Maple-syrup-urine disease
0.026 0.973 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.026 0.973 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.026 0.973 0.001
E72.5 Disorders of glycine metabolism
0.026 0.973 0.001
E72.4 Disorders of ornithine metabolism
0.026 0.973 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.026 0.973 0.001
E72.2 Disorders of urea cycle metabolism
0.026 0.973 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.026 0.973 0.001
E72.0 Disorders of amino-acid transport
0.026 0.973 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.026 0.973 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.026 0.973 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.026 0.973 0.001
E76.2 Other mucopolysaccharidoses
0.026 0.973 0.001
E76.1 Mucopolysaccharidosis, type II
0.026 0.973 0.001
E76.0 Mucopolysaccharidosis, type I
0.026 0.973 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.026 0.973 0.001
E77.8 Other disorders of glycoprotein metabolism
0.026 0.973 0.001
E77.1 Defects in glycoprotein degradation
0.026 0.973 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.026 0.973 0.001
E34 Other endocrine disorders
0.000 0.973 0.027
M12.3 Palindromic rheumatism
0.000 0.973 0.027
E61.9 Deficiency of nutrient element, unspecified
0.001 0.973 0.026
E61.8 Deficiency of other specified nutrient elements
0.001 0.973 0.026
E61.7 Deficiency of multiple nutrient elements
0.001 0.973 0.026
E61.6 Vanadium deficiency
0.001 0.973 0.026
E61.5 Molybdenum deficiency
0.001 0.973 0.026
E61.4 Chromium deficiency
0.001 0.973 0.026
E61.3 Manganese deficiency
0.001 0.973 0.026
E61.0 Copper deficiency
0.001 0.973 0.026
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.973 0.026
E28.9 Ovarian dysfunction, unspecified
0.000 0.974 0.026
E28.8 Other ovarian dysfunction
0.000 0.974 0.026
E28.1 Androgen excess
0.000 0.974 0.026
E28.0 Oestrogen excess
0.000 0.974 0.026
M14 Arthropathies in other diseases classified elsewhere
0.000 0.974 0.026
M12.2 Villonodular synovitis (pigmented)
0.000 0.974 0.026
E55 Vitamin D deficiency
0.001 0.974 0.025
E22 Hyperfunction of pituitary gland
0.000 0.974 0.026
E58 Dietary calcium deficiency
0.001 0.974 0.025
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.025 0.975 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.025 0.975 0.001
E79.1 Lesch-Nyhan syndrome
0.025 0.975 0.001
E29.1 Testicular hypofunction
0.000 0.975 0.025
E80.1 Porphyria cutanea tarda
0.024 0.975 0.001
E23 Hypofunction and other disorders of pituitary gland
0.000 0.975 0.025
E29.9 Testicular dysfunction, unspecified
0.000 0.976 0.024
E29.8 Other testicular dysfunction
0.000 0.976 0.024
E29.0 Testicular hyperfunction
0.000 0.976 0.024
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.976 0.024
M12.5 Traumatic arthropathy
0.000 0.976 0.024
M12.4 Intermittent hydrarthrosis
0.000 0.976 0.024
M12.1 Kaschin-Beck disease
0.000 0.976 0.024
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.976 0.024
E30.9 Disorder of puberty, unspecified
0.000 0.976 0.024
E30.8 Other disorders of puberty
0.000 0.976 0.024
E30.1 Precocious puberty
0.000 0.976 0.024
E30.0 Delayed puberty
0.000 0.976 0.024
E31.9 Polyglandular dysfunction, unspecified
0.000 0.976 0.024
E31.8 Other polyglandular dysfunction
0.000 0.976 0.024
E31.1 Polyglandular hyperfunction
0.000 0.976 0.024
E31.0 Autoimmune polyglandular failure
0.000 0.976 0.024
E32.9 Disease of thymus, unspecified
0.000 0.976 0.024
E32.8 Other diseases of thymus
0.000 0.976 0.024
E32.1 Abscess of thymus
0.000 0.976 0.024
E32.0 Persistent hyperplasia of thymus
0.000 0.976 0.024
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.976 0.024
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.976 0.024
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.976 0.024
E89.3 Postprocedural hypopituitarism
0.023 0.976 0.001
E73.8 Other lactose intolerance
0.023 0.977 0.001
E73.1 Secondary lactase deficiency
0.023 0.977 0.001
E73.0 Congenital lactase deficiency
0.023 0.977 0.001
E80.6 Other disorders of bilirubin metabolism
0.023 0.977 0.001
E25.9 Adrenogenital disorder, unspecified
0.000 0.977 0.023
E25.8 Other adrenogenital disorders
0.000 0.977 0.023
E26 Hyperaldosteronism
0.000 0.977 0.023
I70-I79 Diseases of arteries, arterioles and capillaries
0.023 0.977 0.000
M11.2 Other chondrocalcinosis
0.000 0.977 0.023
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.977 0.022
K93.1 Megacolon in Chagas' disease
0.000 0.977 0.022
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.977 0.022
E28.3 Primary ovarian failure
0.000 0.977 0.023
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.022 0.977 0.001
E44 Protein-energy malnutrition of moderate and mild degree
0.002 0.977 0.020
E45 Retarded development following protein-energy malnutrition
0.002 0.977 0.020
E43 Unspecified severe protein-energy malnutrition
0.002 0.977 0.020
E42 Marasmic kwashiorkor
0.002 0.977 0.020
E41 Nutritional marasmus
0.002 0.977 0.020
E40 Kwashiorkor
0.002 0.977 0.020
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.978 0.022
E80.7 Disorder of bilirubin metabolism, unspecified
0.022 0.978 0.001
E80.5 Crigler-Najjar syndrome
0.022 0.978 0.001
E80.3 Defects of catalase and peroxydase
0.022 0.978 0.001
E80.0 Hereditary erythropoietic porphyria
0.022 0.978 0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.978 0.022
M11.1 Familial chondrocalcinosis
0.000 0.978 0.022
M11.0 Hydroxyapatite deposition disease
0.000 0.978 0.022
I72 Other aneurysm
0.022 0.978 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.000 0.978 0.022
M11.9 Crystal arthropathy, unspecified
0.000 0.978 0.022
E88 Other metabolic disorders
0.021 0.978 0.001
M11.8 Other specified crystal arthropathies
0.000 0.978 0.022
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.978 0.022
I72.4 Aneurysm of artery of lower extremity
0.022 0.978 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.979 0.021
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.979 0.021
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.979 0.021
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.979 0.021
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.979 0.021
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.979 0.021
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.979 0.021
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.979 0.021
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.979 0.021
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.979 0.021
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.979 0.021
M07.18 Arthritis mutilans (Other)
0.000 0.979 0.021
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.979 0.021
M07.16 Arthritis mutilans (Lower leg)
0.000 0.979 0.021
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.979 0.021
M07.14 Arthritis mutilans (Hand)
0.000 0.979 0.021
M07.13 Arthritis mutilans (Forearm)
0.000 0.979 0.021
M07.12 Arthritis mutilans (Upper arm)
0.000 0.979 0.021
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.979 0.021
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.979 0.021
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.979 0.021
M07.28 Psoriatic spondylitis (Other)
0.000 0.979 0.021
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.979 0.021
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.979 0.021
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.979 0.021
M07.24 Psoriatic spondylitis (Hand)
0.000 0.979 0.021
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.979 0.021
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.979 0.021
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.979 0.021
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.979 0.021
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.979 0.021
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.979 0.021
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.979 0.021
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.979 0.021
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.979 0.021
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.979 0.021
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.979 0.021
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.979 0.021
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.979 0.021
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.979 0.021
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.979 0.021
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.979 0.021
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.979 0.021
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.979 0.021
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.979 0.021
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.979 0.021
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.979 0.021
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.000 0.979 0.021
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.000 0.979 0.021
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.000 0.979 0.021
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.979 0.021
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.979 0.021
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.979 0.021
M09.0 Juvenile arthritis in psoriasis
0.000 0.979 0.021

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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