TreeWAS – Variant ID: rs1610742

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10.9 Without complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
E05.0 Thyrotoxicosis with diffuse goitre	0.999	0.001	0.000
K51 Ulcerative colitis	0.000	0.001	0.999
E05.9 Thyrotoxicosis, unspecified	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
M25 Other joint disorders, not elsewhere classified	0.998	0.002	0.000
# Top node	0.998	0.002	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.998	0.002	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.003	0.997
E10.1 With ketoacidosis	0.997	0.003	0.000
L40 Psoriasis	0.996	0.004	0.000
L40.9 Psoriasis, unspecified	0.996	0.004	0.000
M35 Other systemic involvement of connective tissue	0.993	0.007	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.010	0.990
L40.5 Arthropathic psoriasis	0.989	0.011	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.012	0.988
M05-M14 Inflammatory polyarthropathies	0.986	0.014	0.000
M07 Psoriatic and enteropathic arthropathies	0.984	0.016	0.000
M25.5 Pain in joint	0.983	0.017	0.000
M35.0 Sicca syndrome [Sjogren]	0.983	0.017	0.000
M07.3 Other psoriatic arthropathies	0.982	0.018	0.000
L40-L45 Papulosquamous disorders	0.982	0.018	0.000
M25.56 Pain in joint (Lower leg)	0.978	0.022	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.976	0.024	0.000
D50-D53 Nutritional anaemias	0.975	0.025	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.971	0.029	0.000
D50 Iron deficiency anaemia	0.970	0.030	0.000
D50.9 Iron deficiency anaemia, unspecified	0.969	0.031	0.000
E14 Unspecified diabetes mellitus	0.968	0.032	0.000
M31 Other necrotising vasculopathies	0.967	0.033	0.000
M25.4 Effusion of joint	0.960	0.040	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.958	0.042	0.000
E10.3 With ophthalmic complications	0.951	0.049	0.000
E16 Other disorders of pancreatic internal secretion	0.951	0.049	0.000
M31.6 Other giant cell arteritis	0.948	0.052	0.000
K51.4 Pseudopolyposis of colon	0.000	0.059	0.941
E16.2 Hypoglycaemia, unspecified	0.939	0.061	0.000
M25.46 Effusion of joint (Lower leg)	0.937	0.063	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.937	0.063	0.000
K50-K52 Noninfective enteritis and colitis	0.020	0.064	0.916
K51.8 Other ulcerative colitis	0.000	0.067	0.933
M07.39 Other psoriatic arthropathies (Site unspecified)	0.931	0.069	0.000
E10.4 With neurological complications	0.922	0.078	0.000
M60-M63 Disorders of muscles	0.916	0.084	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.915	0.085	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.914	0.086	0.000
K50 Crohn's disease [regional enteritis]	0.001	0.086	0.913
K50.9 Crohn's disease, unspecified	0.000	0.089	0.911
E10.2 With renal complications	0.910	0.090	0.000
E14.3 With ophthalmic complications	0.907	0.093	0.000
D55-D59 Haemolytic anaemias	0.904	0.096	0.000
N00-N08 Glomerular diseases	0.902	0.098	0.000
D80-D89 Certain disorders involving the immune mechanism	0.902	0.098	0.000
N13 Obstructive and reflux uropathy	0.899	0.101	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.899	0.101	0.000
Chapter XIV Diseases of the genitourinary system	0.899	0.101	0.000
N10-N16 Renal tubulo-interstitial diseases	0.895	0.105	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.109	0.891
N08 Glomerular disorders in diseases classified elsewhere	0.889	0.111	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.881	0.119	0.000
M21 Other acquired deformities of limbs	0.879	0.121	0.000
K51.5 Mucosal proctocolitis	0.000	0.125	0.875
N04 Nephrotic syndrome	0.875	0.125	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.873	0.127	0.000
M35.7 Hypermobility syndrome	0.872	0.128	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.871	0.129	0.000
M62 Other disorders of muscle	0.867	0.133	0.000
E07 Other disorders of thyroid	0.864	0.136	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.860	0.140	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.853	0.147	0.000
M86-M90 Other osteopathies	0.852	0.148	0.000
Chapter VI Diseases of the nervous system	0.850	0.150	0.000
N04.9 Unspecified	0.845	0.155	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.841	0.159	0.000
M21.0 Valgus deformity, not elsewhere classified	0.838	0.162	0.000
M32 Systemic lupus erythematosus	0.834	0.165	0.000
D86 Sarcoidosis	0.833	0.167	0.000
E14.5 With peripheral circulatory complications	0.830	0.170	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.830	0.170	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.828	0.172	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.826	0.174	0.000
L40.0 Psoriasis vulgaris	0.824	0.176	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.824	0.176	0.000
G35 Multiple sclerosis	0.822	0.178	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.822	0.178	0.000
D59 Acquired haemolytic anaemia	0.819	0.181	0.000
G30-G32 Other degenerative diseases of the nervous system	0.818	0.182	0.000
M25.54 Pain in joint (Hand)	0.817	0.183	0.000
M62.8 Other specified disorders of muscle	0.815	0.185	0.000
E13 Other specified diabetes mellitus	0.814	0.186	0.000
M10 Gout	0.814	0.186	0.000
M25.9 Joint disorder, unspecified	0.812	0.188	0.000
D60-D64 Aplastic and other anaemias	0.801	0.199	0.000
Chapter I Certain infectious and parasitic diseases	0.801	0.199	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.799	0.201	0.000
E10.0 With coma	0.798	0.202	0.000
M15-M19 Arthrosis	0.798	0.202	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.798	0.202	0.000
L40.1 Generalised pustular psoriasis	0.796	0.204	0.000
M35.3 Polymyalgia rheumatica	0.791	0.209	0.000
M17 Gonarthrosis [arthrosis of knee]	0.787	0.213	0.000
D68 Other coagulation defects	0.787	0.213	0.000
L10-L14 Bullous disorders	0.786	0.214	0.000
L50-L54 Urticaria and erythema	0.786	0.214	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.785	0.215	0.000
M11 Other crystal arthropathies	0.784	0.216	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.783	0.217	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.782	0.218	0.000
N11 Chronic tubulo-interstitial nephritis	0.779	0.220	0.000
M25.47 Effusion of joint (Ankle and foot)	0.779	0.221	0.000
E14.2 Withrenal complications	0.778	0.221	0.000
M25.57 Pain in joint (Ankle and foot)	0.777	0.223	0.000
E07.8 Other specified disorders of thyroid	0.777	0.223	0.000
N05 Unspecified nephritic syndrome	0.776	0.224	0.000
Q76 Congenital malformations of spine and bony thorax	0.776	0.224	0.000
M89 Other disorders of bone	0.773	0.227	0.000
N25-N29 Other disorders of kidney and ureter	0.770	0.230	0.000
E50-E64 Other nutritional deficiencies	0.770	0.230	0.000
E10.7 With multiple complications	0.768	0.232	0.000
M17.9 Gonarthrosis, unspecified	0.767	0.233	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.763	0.237	0.000
M10.0 Idiopathic gout	0.758	0.242	0.000
M25.53 Pain in joint (Forearm)	0.756	0.244	0.000
B02 Zoster [herpes zoster]	0.754	0.246	0.000
G37 Other demyelinating diseases of central nervous system	0.751	0.249	0.000
M17.1 Other primary gonarthrosis	0.750	0.250	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.748	0.252	0.000
M34 Systemic sclerosis	0.748	0.252	0.000
M25.3 Other instability of joint	0.748	0.252	0.000
I83 Varicose veins of lower extremities	0.000	0.252	0.747
M91-M94 Chondropathies	0.747	0.253	0.000
E10.8 With unspecified complications	0.743	0.257	0.000
B35-B49 Mycoses	0.738	0.262	0.000
L42 Pityriasis rosea	0.738	0.262	0.000
M07.6 Other enteropathic arthropathies	0.736	0.264	0.000
M25.44 Effusion of joint (Hand)	0.735	0.265	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.734	0.266	0.000
B00 Herpesviral [herpes simplex] infections	0.734	0.266	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.734	0.266	0.000
G70-G73 Diseases of myoneural junction and muscle	0.734	0.266	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.733	0.267	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.732	0.268	0.000
M12 Other specific arthropathies	0.732	0.268	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.731	0.269	0.000
M25.42 Effusion of joint (Upper arm)	0.730	0.270	0.000
M00-M03 Infectious arthropathies	0.729	0.271	0.000
M25.51 Pain in joint (Shoulder region)	0.728	0.272	0.000
D66 Hereditary factor VIII deficiency	0.728	0.272	0.000
Q00-Q07 Congenital malformations of the nervous system	0.727	0.273	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.726	0.274	0.000
K50.8 Other Crohn's disease	0.000	0.274	0.725
E14.9 Without complications	0.725	0.275	0.000
M31.1 Thrombotic microangiopathy	0.725	0.275	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.723	0.277	0.000
E10.6 With other specified complications	0.723	0.277	0.000
D50.1 Sideropenic dysphagia	0.723	0.277	0.000
M31.0 Hypersensitivity angiitis	0.722	0.277	0.000
M31.9 Necrotising vasculopathy, unspecified	0.722	0.278	0.000
D86.0 Sarcoidosis of lung	0.721	0.279	0.000
M31.7 Microscopic polyangiitis	0.720	0.280	0.000
M25.58 Pain in joint (Other)	0.720	0.280	0.000
L40.3 Pustulosis palmaris et plantaris	0.720	0.280	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.720	0.280	0.000
E14.8 With unspecified complications	0.719	0.281	0.000
D59.1 Other autoimmune haemolytic anaemias	0.719	0.281	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.716	0.284	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.716	0.284	0.000
M25.2 Flail joint	0.716	0.284	0.000
M25.1 Fistula of joint	0.716	0.284	0.000
G31.8 Other specified degenerative diseases of nervous system	0.716	0.284	0.000
M25.43 Effusion of joint (Forearm)	0.716	0.284	0.000
M24 Other specific joint derangements	0.715	0.285	0.000
L40.4 Guttate psoriasis	0.714	0.286	0.000
L40.2 Acrodermatitis continua	0.714	0.286	0.000
N04.2 Diffuse membranous glomerulonephritis	0.714	0.286	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.712	0.288	0.000
M35.8 Other specified systemic involvement of connective tissue	0.712	0.288	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.712	0.288	0.000
M35.5 Multifocal fibrosclerosis	0.712	0.288	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.712	0.288	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.712	0.288	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.711	0.289	0.000
B02.9 Zoster without complication	0.710	0.290	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.292	0.708
M09 Juvenile arthritis in diseases classified elsewhere	0.707	0.293	0.000
M08 Juvenile arthritis	0.707	0.293	0.000
E14.1 With ketoacidosis	0.706	0.294	0.000
M07.5 Arthropathy in ulcerative colitis	0.705	0.295	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.705	0.295	0.000
M07.2 Psoriatic spondylitis	0.705	0.295	0.000
M07.1 Arthritis mutilans	0.705	0.295	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.705	0.295	0.000
M07.38 Other psoriatic arthropathies (Other)	0.704	0.296	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.704	0.296	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.704	0.296	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.704	0.296	0.000
L44 Other papulosquamous disorders	0.704	0.296	0.000
L41 Parapsoriasis	0.704	0.296	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.704	0.296	0.000
D58 Other hereditary haemolytic anaemias	0.700	0.300	0.000
G31.0 Circumscribed brain atrophy	0.700	0.300	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.697	0.303	0.000
E15 Nondiabetic hypoglycaemic coma	0.696	0.303	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.694	0.306	0.000
E14.7 With multiple complications	0.694	0.306	0.000
E14.0 With coma	0.694	0.306	0.000
D62 Acute posthaemorrhagic anaemia	0.694	0.306	0.000
D68.9 Coagulation defect, unspecified	0.693	0.307	0.000
M31.8 Other specified necrotising vasculopathies	0.693	0.307	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.693	0.307	0.000
M31.2 Lethal midline granuloma	0.693	0.307	0.000
A15-A19 Tuberculosis	0.693	0.307	0.000
D69 Purpura and other haemorrhagic conditions	0.692	0.308	0.000
D83 Common variable immunodeficiency	0.692	0.308	0.000
K90 Intestinal malabsorption	0.692	0.308	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.691	0.309	0.000
E05.8 Other thyrotoxicosis	0.690	0.310	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.311	0.689
M25.49 Effusion of joint (Site unspecified)	0.688	0.312	0.000
M25.48 Effusion of joint (Other)	0.688	0.312	0.000
M21.8 Other specified acquired deformities of limbs	0.688	0.312	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.687	0.313	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.687	0.313	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.687	0.313	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.314	0.686
N26 Unspecified contracted kidney	0.686	0.314	0.000
M35.1 Other overlap syndromes	0.685	0.315	0.000
M14 Arthropathies in other diseases classified elsewhere	0.683	0.317	0.000
M89.5 Osteolysis	0.683	0.317	0.000
D68.8 Other specified coagulation defects	0.682	0.318	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.682	0.318	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.682	0.318	0.000
E16.4 Abnormal secretion of gastrin	0.682	0.318	0.000
E16.3 Increased secretion of glucagon	0.682	0.318	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.681	0.319	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.681	0.319	0.000
D73 Diseases of spleen	0.680	0.320	0.000
E14.6 With other specified complications	0.680	0.320	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.679	0.321	0.000
D64 Other anaemias	0.679	0.321	0.000
M21.6 Other acquired deformities of ankle and foot	0.677	0.323	0.000
D80 Immunodeficiency with predominantly antibody defects	0.675	0.325	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.675	0.325	0.000
N02 Recurrent and persistent haematuria	0.674	0.325	0.000
N13.6 Pyonephrosis	0.673	0.327	0.000
Q65 Congenital deformities of hip	0.672	0.328	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.672	0.328	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.672	0.328	0.000
N25 Disorders resulting from impaired renal tubular function	0.672	0.328	0.000
B37 Candidiasis	0.670	0.330	0.000
M25.52 Pain in joint (Upper arm)	0.668	0.332	0.000
D86.9 Sarcoidosis, unspecified	0.668	0.332	0.000
N00 Acute nephritic syndrome	0.667	0.332	0.000
M21.1 Varus deformity, not elsewhere classified	0.666	0.334	0.000
Q76.0 Spina bifida occulta	0.665	0.335	0.000
B02.2 Zoster with other nervous system involvement	0.664	0.336	0.000
M86 Osteomyelitis	0.662	0.338	0.000
M25.59 Pain in joint (Site unspecified)	0.659	0.341	0.000
D86.3 Sarcoidosis of skin	0.659	0.341	0.000
D84 Other immunodeficiencies	0.659	0.341	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.658	0.342	0.000
E13.9 Without complications	0.658	0.342	0.000
D68.0 Von Willebrand's disease	0.657	0.343	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.657	0.343	0.000
M62.88 Other specified disorders of muscle (Other)	0.657	0.343	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.657	0.343	0.000
M61 Calcification and ossification of muscle	0.657	0.343	0.000
M33 Dermatopolymyositis	0.656	0.344	0.000
D67 Hereditary factor IX deficiency	0.655	0.345	0.000
Q78 Other osteochondrodysplasias	0.652	0.348	0.000
M25.7 Osteophyte	0.652	0.348	0.000
N05.2 Diffuse membranous glomerulonephritis	0.651	0.349	0.000
M25.41 Effusion of joint (Shoulder region)	0.650	0.349	0.000
E06 Thyroiditis	0.650	0.350	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.650	0.350	0.000
E40-E46 Malnutrition	0.648	0.352	0.000
D57 Sickle-cell disorders	0.648	0.352	0.000
D55 Anaemia due to enzyme disorders	0.648	0.352	0.000
M89.3 Hypertrophy of bone	0.648	0.352	0.000
G70 Myasthenia gravis and other myoneural disorders	0.647	0.353	0.000
D56 Thalassaemia	0.647	0.353	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.647	0.353	0.000
N06 Isolated proteinuria with specified morphological lesion	0.647	0.353	0.000
N01 Rapidly progressive nephritic syndrome	0.647	0.353	0.000
D82 Immunodeficiency associated with other major defects	0.647	0.353	0.000
D81 Combined immunodeficiencies	0.647	0.353	0.000
N04.1 Focal and segmental glomerular lesions	0.645	0.355	0.000
M30 Polyarteritis nodosa and related conditions	0.645	0.355	0.000
M11.2 Other chondrocalcinosis	0.644	0.356	0.000
L53 Other erythematous conditions	0.642	0.358	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.642	0.358	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.640	0.360	0.000
L40.8 Other psoriasis	0.639	0.361	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.639	0.361	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.637	0.363	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.637	0.363	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.637	0.363	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.637	0.363	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.637	0.363	0.000
M62.0 Diastasis of muscle	0.637	0.363	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.637	0.363	0.000
B00.9 Herpesviral infection, unspecified	0.637	0.363	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.636	0.364	0.000
A20-A28 Certain zoonotic bacterial diseases	0.635	0.365	0.000
Q74 Other congenital malformations of limb(s)	0.635	0.365	0.000
M93 Other osteochondropathies	0.634	0.366	0.000
E16.1 Other hypoglycaemia	0.633	0.366	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.633	0.367	0.000
M25.0 Haemarthrosis	0.632	0.367	0.000
M21.9 Acquired deformity of limb, unspecified	0.630	0.370	0.000
M25.76 Osteophyte (Lower leg)	0.630	0.370	0.000
Q35-Q37 Cleft lip and cleft palate	0.629	0.371	0.000
K50.1 Crohn's disease of large intestine	0.000	0.371	0.629
M17.5 Other secondary gonarthrosis	0.628	0.372	0.000
D86.1 Sarcoidosis of lymph nodes	0.628	0.372	0.000
N04.8 Other	0.627	0.373	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.627	0.373	0.000
N04.6 Dense deposit disease	0.627	0.373	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.627	0.373	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.627	0.373	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.627	0.373	0.000
M35.2 Behcet's disease	0.627	0.373	0.000
M89.0 Algoneurodystrophy	0.627	0.373	0.000
M25.36 Other instability of joint (Lower leg)	0.626	0.374	0.000
B00.5 Herpesviral ocular disease	0.625	0.375	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.625	0.375	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.625	0.375	0.000
Q50-Q56 Congenital malformations of genital organs	0.624	0.376	0.000
M10.00 Idiopathic gout (Multiple sites)	0.623	0.377	0.000
M24.1 Other articular cartilage disorders	0.623	0.377	0.000
E61 Deficiency of other nutrient elements	0.623	0.377	0.000
M62.6 Muscle strain	0.623	0.377	0.000
M62.9 Disorder of muscle, unspecified	0.622	0.378	0.000
M62.4 Contracture of muscle	0.622	0.378	0.000
M62.3 Immobility syndrome (paraplegic)	0.622	0.378	0.000
M62.2 Ischaemic infarction of muscle	0.622	0.378	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.622	0.378	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.622	0.378	0.000
D86.8 Sarcoidosis of other and combined sites	0.621	0.379	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.621	0.379	0.000
N11.1 Chronic obstructive pyelonephritis	0.620	0.380	0.000
E07.1 Dyshormogenetic goitre	0.619	0.381	0.000
E07.0 Hypersecretion of calcitonin	0.619	0.381	0.000
L12 Pemphigoid	0.619	0.381	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.618	0.382	0.000
L13 Other bullous disorders	0.618	0.382	0.000
N05.1 Focal and segmental glomerular lesions	0.618	0.382	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.618	0.382	0.000
E13.3 With ophthalmic complications	0.617	0.383	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.617	0.383	0.000
L52 Erythema nodosum	0.616	0.384	0.000
B37.8 Candidiasis of other sites	0.615	0.385	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.614	0.386	0.000
M10.02 Idiopathic gout (Upper arm)	0.614	0.386	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.613	0.387	0.000
A65-A69 Other spirochaetal diseases	0.613	0.387	0.000
N04.0 Minor glomerular abnormality	0.611	0.389	0.000
E14.4 With neurological complications	0.610	0.390	0.000
M10.06 Idiopathic gout (Lower leg)	0.610	0.390	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.609	0.391	0.000
D64.9 Anaemia, unspecified	0.608	0.392	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.392	0.608
D53 Other nutritional anaemias	0.608	0.392	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.607	0.393	0.000
D52 Folate deficiency anaemia	0.605	0.395	0.000
E10.5 With peripheral circulatory complications	0.605	0.395	0.000
B01 Varicella [chickenpox]	0.603	0.397	0.000
G36 Other acute disseminated demyelination	0.603	0.397	0.000
M60 Myositis	0.602	0.397	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.602	0.398	0.000
D73.5 Infarction of spleen	0.602	0.398	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.601	0.399	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.601	0.399	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.601	0.399	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.601	0.399	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.601	0.399	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.601	0.399	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.601	0.399	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.601	0.399	0.000
B00.1 Herpesviral vesicular dermatitis	0.600	0.400	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.600	0.400	0.000
Q68 Other congenital musculoskeletal deformities	0.599	0.401	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.598	0.402	0.000
M32.8 Other forms of systemic lupus erythematosus	0.598	0.402	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.598	0.402	0.000
Q76.1 Klippel-Feil syndrome	0.594	0.406	0.000
N15 Other renal tubulo-interstitial diseases	0.594	0.406	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.594	0.406	0.000
Q40 Other congenital malformations of upper alimentary tract	0.593	0.407	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.592	0.408	0.000
Q75 Other congenital malformations of skull and face bones	0.592	0.408	0.000
Q73 Reduction defects of unspecified limb	0.592	0.408	0.000
Q72 Reduction defects of lower limb	0.592	0.408	0.000
Q71 Reduction defects of upper limb	0.592	0.408	0.000
Q70 Syndactyly	0.592	0.408	0.000
Q69 Polydactyly	0.592	0.408	0.000
M90 Osteopathies in diseases classified elsewhere	0.590	0.410	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.589	0.410	0.000
E07.9 Disorder of thyroid, unspecified	0.589	0.411	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.588	0.412	0.000
D59.8 Other acquired haemolytic anaemias	0.587	0.412	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.587	0.412	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.587	0.412	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.587	0.412	0.000
D59.3 Haemolytic-uraemic syndrome	0.587	0.412	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.587	0.412	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.587	0.412	0.000
E51 Thiamine deficiency	0.587	0.413	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.584	0.415	0.000
M24.2 Disorder of ligament	0.584	0.416	0.000
E13.8 With unspecified complications	0.584	0.416	0.000
E13.7 With multiple complications	0.584	0.416	0.000
E13.6 With other specified complications	0.584	0.416	0.000
E13.5 With peripheral circulatory complications	0.584	0.416	0.000
E13.4 With neurological complications	0.584	0.416	0.000
E13.2 With renal complications	0.584	0.416	0.000
E13.1 With ketoacidosis	0.584	0.416	0.000
E13.0 With coma	0.584	0.416	0.000
M10.4 Other secondary gout	0.583	0.416	0.000
M10.3 Gout due to impairment of renal function	0.583	0.416	0.000
M10.2 Drug-induced gout	0.583	0.416	0.000
M10.1 Lead-induced gout	0.583	0.416	0.000
N05.8 Other	0.583	0.417	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.582	0.418	0.000
M25.98 Joint disorder, unspecified (Other)	0.582	0.418	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.582	0.418	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.582	0.418	0.000
E56 Other vitamin deficiencies	0.581	0.419	0.000
Q05 Spina bifida	0.580	0.419	0.000
M62.84 Other specified disorders of muscle (Hand)	0.580	0.419	0.000
G70.0 Myasthenia gravis	0.580	0.420	0.000
Q03 Congenital hydrocephalus	0.580	0.420	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.579	0.420	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.579	0.420	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.579	0.421	0.000
B36 Other superficial mycoses	0.579	0.421	0.000
B25-B34 Other viral diseases	0.578	0.422	0.000
M21.2 Flexion deformity	0.578	0.422	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.577	0.422	0.000
M88 Paget's disease of bone [osteitis deformans]	0.576	0.424	0.000
M25.33 Other instability of joint (Forearm)	0.576	0.424	0.000
K90.9 Intestinal malabsorption, unspecified	0.576	0.424	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.574	0.426	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.574	0.426	0.000
A75-A79 Rickettsioses	0.574	0.426	0.000
A70-A74 Other diseases caused by chlamydiae	0.574	0.426	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.573	0.427	0.000
M12.2 Villonodular synovitis (pigmented)	0.572	0.428	0.000
D61 Other aplastic anaemias	0.572	0.428	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.572	0.428	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.572	0.428	0.000
M25.50 Pain in joint (Multiple sites)	0.572	0.428	0.000
N02.9 Unspecified	0.572	0.428	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.572	0.428	0.000
D68.5 Primary Thrombophilia	0.571	0.429	0.000
M21.4 Flat foot [pes planus] (acquired)	0.570	0.429	0.000
D72 Other disorders of white blood cells	0.570	0.430	0.000
L53.8 Other specified erythematous conditions	0.570	0.430	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.570	0.430	0.000
N13.4 Hydroureter	0.568	0.431	0.000
B37.9 Candidiasis, unspecified	0.568	0.432	0.000
M11.8 Other specified crystal arthropathies	0.568	0.432	0.000
K50.0 Crohn's disease of small intestine	0.000	0.432	0.567
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.567	0.433	0.000
E11 Non-insulin-dependent diabetes mellitus	0.566	0.434	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.564	0.435	0.000
D69.4 Other primary thrombocytopenia	0.565	0.435	0.000
L10 Pemphigus	0.564	0.436	0.000
L14 Bullous disorders in diseases classified elsewhere	0.564	0.436	0.000
B99-B99 Other infectious diseases	0.564	0.436	0.000
L54 Erythema in diseases classified elsewhere	0.563	0.437	0.000
L50 Urticaria	0.563	0.437	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.563	0.437	0.000
M34.9 Systemic sclerosis, unspecified	0.562	0.437	0.000
M11.1 Familial chondrocalcinosis	0.562	0.438	0.000
M11.0 Hydroxyapatite deposition disease	0.562	0.438	0.000
Q65.8 Other congenital deformities of hip	0.562	0.438	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.562	0.438	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.561	0.439	0.000
B06 Rubella [German measles]	0.561	0.439	0.000
B05 Measles	0.561	0.439	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.561	0.439	0.000
B04 Monkeypox	0.561	0.439	0.000
B03 Smallpox	0.561	0.439	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations