TreeWAS – Variant ID: rs1611350

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	0.999	0.001	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.999	0.001	0.000
E10.3 With ophthalmic complications	0.999	0.001	0.000
E10.1 With ketoacidosis	0.998	0.002	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.993	0.007	0.000
E16 Other disorders of pancreatic internal secretion	0.988	0.012	0.000
E16.2 Hypoglycaemia, unspecified	0.986	0.014	0.000
E10.4 With neurological complications	0.977	0.023	0.000
E14 Unspecified diabetes mellitus	0.968	0.032	0.000
E10.2 With renal complications	0.965	0.035	0.000
E11 Non-insulin-dependent diabetes mellitus	0.945	0.055	0.000
E50-E64 Other nutritional deficiencies	0.913	0.087	0.000
E14.3 With ophthalmic complications	0.902	0.098	0.000
L40.0 Psoriasis vulgaris	0.899	0.101	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.888	0.112	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.883	0.117	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.882	0.118	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.881	0.119	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.874	0.126	0.000
E13 Other specified diabetes mellitus	0.867	0.133	0.000
C81 Hodgkin's disease	0.852	0.148	0.000
E10.0 With coma	0.842	0.158	0.000
E14.5 With peripheral circulatory complications	0.824	0.176	0.000
E61 Deficiency of other nutrient elements	0.821	0.179	0.000
E07 Other disorders of thyroid	0.820	0.180	0.000
E11.9 Without complications	0.813	0.187	0.000
E14.8 With unspecified complications	0.812	0.188	0.000
C84.5 Other and unspecified T-cell lymphomas	0.808	0.192	0.000
E55 Vitamin D deficiency	0.806	0.194	0.000
E11.1 With ketoacidosis	0.804	0.196	0.000
E11.5 With peripheral circulatory complications	0.802	0.198	0.000
E06 Thyroiditis	0.800	0.200	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.797	0.203	0.000
E10.6 With other specified complications	0.796	0.204	0.000
C81.9 Hodgkin's disease, unspecified	0.792	0.208	0.000
C85.1 B-cell lymphoma, unspecified	0.787	0.213	0.000
E14.1 With ketoacidosis	0.781	0.219	0.000
L40.1 Generalised pustular psoriasis	0.780	0.220	0.000
C84.4 Peripheral T-cell lymphoma	0.778	0.222	0.000
E10.7 With multiple complications	0.768	0.232	0.000
E14.4 With neurological complications	0.759	0.241	0.000
E61.1 Iron deficiency	0.758	0.242	0.000
C84.0 Mycosis fungoides	0.757	0.243	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.755	0.245	0.000
C95 Leukaemia of unspecified cell type	0.752	0.248	0.000
E11.8 With unspecified complications	0.748	0.252	0.000
E13.9 Without complications	0.745	0.255	0.000
E11.7 With multiple complications	0.743	0.257	0.000
E11.2 With renal complications	0.743	0.257	0.000
E14.6 With other specified complications	0.739	0.261	0.000
C90.2 Plasmacytoma, extramedullary	0.734	0.266	0.000
E55.9 Vitamin D deficiency, unspecified	0.729	0.271	0.000
E10.8 With unspecified complications	0.720	0.279	0.000
C81.2 Mixed cellularity	0.719	0.281	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
L40.8 Other psoriasis	0.715	0.285	0.000
E15 Nondiabetic hypoglycaemic coma	0.712	0.288	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.709	0.291	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.709	0.291	0.000
E16.4 Abnormal secretion of gastrin	0.709	0.291	0.000
E16.3 Increased secretion of glucagon	0.709	0.291	0.000
C81.0 Lymphocytic predominance	0.706	0.294	0.000
E14.7 With multiple complications	0.694	0.306	0.000
E14.0 With coma	0.694	0.306	0.000
E06.9 Thyroiditis, unspecified	0.694	0.306	0.000
E11.6 With other specified complications	0.693	0.307	0.000
E07.8 Other specified disorders of thyroid	0.691	0.309	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.684	0.315	0.000
L40.3 Pustulosis palmaris et plantaris	0.684	0.316	0.000
E11.0 With coma	0.681	0.319	0.000
E13.3 With ophthalmic complications	0.677	0.323	0.000
E14.2 Withrenal complications	0.675	0.325	0.000
C86 Other specified types of T/NK-cell lymphoma	0.675	0.325	0.000
C88 Malignant immunoproliferative diseases	0.670	0.330	0.000
E51 Thiamine deficiency	0.667	0.333	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.666	0.334	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.655	0.345	0.000
E63 Other nutritional deficiencies	0.655	0.345	0.000
E50 Vitamin A deficiency	0.655	0.345	0.000
E60 Dietary zinc deficiency	0.655	0.345	0.000
E59 Dietary selenium deficiency	0.655	0.345	0.000
E58 Dietary calcium deficiency	0.655	0.345	0.000
E54 Ascorbic acid deficiency	0.655	0.345	0.000
E52 Niacin deficiency [pellagra]	0.655	0.345	0.000
D50 Iron deficiency anaemia	0.649	0.351	0.000
E10.5 With peripheral circulatory complications	0.647	0.353	0.000
D50.9 Iron deficiency anaemia, unspecified	0.647	0.353	0.000
D50-D53 Nutritional anaemias	0.642	0.358	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.638	0.362	0.000
E05.8 Other thyrotoxicosis	0.637	0.363	0.000
C93 Monocytic leukaemia	0.636	0.364	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.633	0.367	0.000
C85.0 Lymphosarcoma	0.633	0.367	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.632	0.367	0.000
C94 Other leukaemias of specified cell type	0.632	0.367	0.000
E40-E46 Malnutrition	0.629	0.371	0.000
K90 Intestinal malabsorption	0.628	0.372	0.000
E56 Other vitamin deficiencies	0.628	0.372	0.000
D60-D64 Aplastic and other anaemias	0.628	0.372	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.627	0.373	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.627	0.373	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.627	0.373	0.000
C84.3 Lymphoepithelioid lymphoma	0.627	0.373	0.000
C84.2 T-zone lymphoma	0.627	0.373	0.000
C84.1 Sezary's diease	0.627	0.373	0.000
E13.8 With unspecified complications	0.622	0.378	0.000
E13.7 With multiple complications	0.622	0.378	0.000
E13.6 With other specified complications	0.622	0.378	0.000
E13.5 With peripheral circulatory complications	0.622	0.378	0.000
E13.4 With neurological complications	0.622	0.378	0.000
E13.2 With renal complications	0.622	0.378	0.000
E13.1 With ketoacidosis	0.622	0.378	0.000
E13.0 With coma	0.622	0.378	0.000
D50.8 Other iron deficiency anaemias	0.622	0.378	0.000
E16.1 Other hypoglycaemia	0.621	0.379	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.615	0.384	0.000
C81.7 Other Hodgkin's disease	0.611	0.389	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.611	0.389	0.000
C81.3 Lymphocytic depletion	0.611	0.389	0.000
D61 Other aplastic anaemias	0.610	0.390	0.000
C95.9 Leukaemia, unspecified	0.606	0.394	0.000
C90.3 Solitary plasmacytoma	0.603	0.397	0.000
L40-L45 Papulosquamous disorders	0.601	0.399	0.000
C81.1 Nodular sclerosis	0.597	0.403	0.000
D61.9 Aplastic anaemia, unspecified	0.594	0.406	0.000
E03 Other hypothyroidism	0.594	0.406	0.000
C91 Lymphoid leukaemia	0.590	0.410	0.000
E07.9 Disorder of thyroid, unspecified	0.589	0.411	0.000
E61.9 Deficiency of nutrient element, unspecified	0.588	0.412	0.000
E61.8 Deficiency of other specified nutrient elements	0.588	0.412	0.000
E61.7 Deficiency of multiple nutrient elements	0.588	0.412	0.000
E61.6 Vanadium deficiency	0.588	0.412	0.000
E61.5 Molybdenum deficiency	0.588	0.412	0.000
E61.4 Chromium deficiency	0.588	0.412	0.000
E61.3 Manganese deficiency	0.588	0.412	0.000
E61.0 Copper deficiency	0.588	0.412	0.000
E07.1 Dyshormogenetic goitre	0.588	0.412	0.000
E07.0 Hypersecretion of calcitonin	0.588	0.412	0.000
E06.5 Other chronic thyroiditis	0.586	0.413	0.000
E11.3 With ophthalmic complications	0.585	0.415	0.000
E55.0 Rickets, active	0.578	0.422	0.000
E61.2 Magnesium deficiency	0.574	0.425	0.000
E06.4 Drug-induced thyroiditis	0.574	0.426	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.574	0.426	0.000
E06.1 Subacute thyroiditis	0.574	0.426	0.000
E06.0 Acute thyroiditis	0.574	0.426	0.000
D55-D59 Haemolytic anaemias	0.572	0.428	0.000
D80-D89 Certain disorders involving the immune mechanism	0.565	0.435	0.000
C90.1 Plasma cell leukaemia	0.564	0.435	0.000
D51 Vitamin B12 deficiency anaemia	0.560	0.439	0.000
D62 Acute posthaemorrhagic anaemia	0.555	0.445	0.000
C90.0 Multiple myeloma	0.553	0.447	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.548	0.451	0.000
C95.7 Other leukaemia of unspecified cell type	0.539	0.461	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.539	0.461	0.000
C95.0 Acute leukaemia of unspecified cell type	0.539	0.461	0.000
D64 Other anaemias	0.535	0.465	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.527	0.473	0.000
D86 Sarcoidosis	0.520	0.480	0.000
C77.1 Intrathoracic lymph nodes	0.519	0.481	0.000
E53 Deficiency of other B group vitamins	0.516	0.484	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.509	0.491	0.000
D59 Acquired haemolytic anaemia	0.496	0.504	0.000
K90.8 Other intestinal malabsorption	0.493	0.507	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.492	0.508	0.000
E51.2 Wernicke's encephalopathy	0.491	0.509	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.484	0.516	0.000
C86.4 Blastic NK-cell lymphoma	0.484	0.516	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.484	0.516	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.484	0.516	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.484	0.516	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.484	0.516	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.481	0.519	0.000
C88.7 Other malignant immunoproliferative diseases	0.481	0.519	0.000
C88.3 Immunoproliferative small intestinal disease	0.481	0.519	0.000
C88.2 Gamma heavy chain disease	0.481	0.519	0.000
C88.1 Alpha heavy chain disease	0.481	0.519	0.000
E06.3 Autoimmune thyroiditis	0.480	0.520	0.000
D86.0 Sarcoidosis of lung	0.479	0.521	0.000
E51.9 Thiamine deficiency, unspecified	0.478	0.521	0.000
E51.8 Other manifestations of thiamine deficiency	0.478	0.521	0.000
E51.1 Beriberi	0.478	0.521	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.476	0.524	0.000
C91.4 Hairy-cell leukaemia	0.473	0.527	0.000
D64.9 Anaemia, unspecified	0.472	0.528	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.472	0.528	0.000
D58 Other hereditary haemolytic anaemias	0.471	0.529	0.000
R53 Malaise and fatigue	0.470	0.530	0.000
E50.9 Vitamin A deficiency, unspecified	0.469	0.530	0.000
E50.8 Other manifestations of vitamin A deficiency	0.469	0.530	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.469	0.530	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.469	0.530	0.000
E50.5 Vitamin A deficiency with night blindness	0.469	0.530	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.469	0.530	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.469	0.530	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.469	0.530	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.469	0.530	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.469	0.530	0.000
E63.9 Nutritional deficiency, unspecified	0.469	0.530	0.000
E63.8 Other specified nutritional deficiencies	0.469	0.530	0.000
E63.1 Imbalance of constituents of food intake	0.469	0.530	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.469	0.530	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.469	0.530	0.000
E64.8 Sequelae of other nutritional deficiencies	0.469	0.530	0.000
E64.3 Sequelae of rickets	0.469	0.530	0.000
E64.2 Sequelae of vitamin C deficiency	0.469	0.530	0.000
E64.1 Sequelae of vitamin A deficiency	0.469	0.530	0.000
E64.0 Sequelae of protein-energy malnutrition	0.469	0.530	0.000
D50.1 Sideropenic dysphagia	0.468	0.532	0.000
D61.1 Drug-induced aplastic anaemia	0.467	0.533	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.465	0.535	0.000
C93.1 Chronic monocytic leukaemia	0.459	0.540	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.456	0.544	0.000
C93.9 Monocytic leukaemia, unspecified	0.456	0.544	0.000
C93.7 Other monocytic leukaemia	0.456	0.544	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.456	0.544	0.000
C93.2 Subacute monocytic leukaemia	0.456	0.544	0.000
C93.0 Acute monocytic leukaemia	0.456	0.544	0.000
L42 Pityriasis rosea	0.455	0.545	0.000
C94.7 Other specified leukaemias	0.453	0.546	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.453	0.546	0.000
C94.5 Acute myelofibrosis	0.453	0.546	0.000
C94.4 Acute panmyelosis	0.453	0.546	0.000
C94.3 Mast cell leukaemia	0.453	0.546	0.000
C94.2 Acute megakaryoblastic leukaemia	0.453	0.546	0.000
C94.1 Chronic erythraemia	0.453	0.546	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.453	0.546	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.453	0.546	0.000
C96.8 Histiocytic sarcoma	0.453	0.546	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.453	0.546	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.453	0.546	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.453	0.546	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.453	0.546	0.000
C96.3 True histiocytic lymphoma	0.453	0.546	0.000
C96.2 Malignant mast cell tumour	0.453	0.546	0.000
C96.1 Malignant histiocytosis	0.453	0.546	0.000
C96.0 Letterer-Siwe disease	0.453	0.546	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.452	0.548	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.451	0.549	0.000
E45 Retarded development following protein-energy malnutrition	0.451	0.549	0.000
E43 Unspecified severe protein-energy malnutrition	0.451	0.549	0.000
E42 Marasmic kwashiorkor	0.451	0.549	0.000
E41 Nutritional marasmus	0.451	0.549	0.000
E40 Kwashiorkor	0.451	0.549	0.000
K90.3 Pancreatic steatorrhoea	0.450	0.549	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.450	0.549	0.000
K90.1 Tropical sprue	0.450	0.549	0.000
E56.9 Vitamin deficiency, unspecified	0.450	0.550	0.000
E56.8 Deficiency of other vitamins	0.450	0.550	0.000
E56.0 Deficiency of vitamin E	0.450	0.550	0.000
D80 Immunodeficiency with predominantly antibody defects	0.450	0.550	0.000
K90.9 Intestinal malabsorption, unspecified	0.447	0.553	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.446	0.554	0.000
D61.0 Constitutional aplastic anaemia	0.443	0.557	0.000
C91.9 Lymphoid leukaemia, unspecified	0.440	0.560	0.000
D86.9 Sarcoidosis, unspecified	0.439	0.561	0.000
Chapter II Neoplasms	0.439	0.561	0.000
D61.8 Other specified aplastic anaemias	0.437	0.563	0.000
D61.3 Idiopathic aplastic anaemia	0.437	0.563	0.000
D61.2 Aplastic anaemia due to other external agents	0.437	0.563	0.000
# Top node	0.436	0.564	0.000
D59.1 Other autoimmune haemolytic anaemias	0.434	0.566	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.434	0.566	0.000
D83 Common variable immunodeficiency	0.431	0.569	0.000
L44 Other papulosquamous disorders	0.431	0.569	0.000
L41 Parapsoriasis	0.431	0.569	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.431	0.569	0.000
E03.8 Other specified hypothyroidism	0.431	0.569	0.000
E03.5 Myxoedema coma	0.426	0.574	0.000
E03.4 Atrophy of thyroid (acquired)	0.426	0.574	0.000
E03.3 Postinfectious hypothyroidism	0.426	0.574	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.425	0.575	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.425	0.575	0.000
C91.5 Adult T-cell leukaemia	0.423	0.576	0.000
E56.1 Deficiency of vitamin K	0.423	0.577	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.423	0.577	0.000
C91.7 Other lymphoid leukaemia	0.423	0.577	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.423	0.577	0.000
C91.3 Prolymphocytic leukaemia	0.423	0.577	0.000
C91.2 Subacute lymphocytic leukaemia	0.423	0.577	0.000
D56 Thalassaemia	0.411	0.589	0.000
D57 Sickle-cell disorders	0.410	0.589	0.000
D55 Anaemia due to enzyme disorders	0.410	0.589	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.406	0.594	0.000
D81 Combined immunodeficiencies	0.405	0.595	0.000
E03.1 Congenital hypothyroidism without goitre	0.402	0.598	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.402	0.598	0.000
D51.2 Transcobalamin II deficiency	0.402	0.598	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.402	0.598	0.000
D53 Other nutritional anaemias	0.400	0.600	0.000
E11.4 With neurological complications	0.399	0.601	0.000
C60-C63 Malignant neoplasms of male genital organs	0.398	0.602	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.397	0.603	0.000
D82 Immunodeficiency associated with other major defects	0.394	0.606	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.391	0.609	0.000
C34 Malignant neoplasm of bronchus and lung	0.390	0.610	0.000
C62 Malignant neoplasm of testis	0.388	0.612	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.385	0.614	0.000
D64.4 Congenital dyserythropoietic anaemia	0.384	0.616	0.000
D64.3 Other sideroblastic anaemias	0.384	0.616	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.384	0.616	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.384	0.616	0.000
D64.0 Hereditary sideroblastic anaemia	0.384	0.616	0.000
D58.2 Other haemoglobinopathies	0.384	0.616	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.383	0.617	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.381	0.619	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.381	0.619	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.380	0.620	0.000
D86.3 Sarcoidosis of skin	0.380	0.620	0.000
C34.0 Main bronchus	0.378	0.622	0.000
D64.8 Other specified anaemias	0.375	0.625	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.374	0.626	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.374	0.626	0.000
C62.9 Testis, unspecified	0.372	0.628	0.000
E53.1 Pyridoxine deficiency	0.370	0.630	0.000
E53.0 Riboflavin deficiency	0.370	0.630	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.366	0.634	0.000
C92 Myeloid leukaemia	0.365	0.635	0.000
C02.9 Tongue, unspecified	0.363	0.637	0.000
E46 Unspecified protein-energy malnutrition	0.363	0.637	0.000
D58.0 Hereditary spherocytosis	0.361	0.639	0.000
C34.3 Lower lobe, bronchus or lung	0.359	0.641	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.357	0.643	0.000
D66 Hereditary factor VIII deficiency	0.356	0.643	0.000
D59.8 Other acquired haemolytic anaemias	0.356	0.644	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.356	0.644	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.356	0.644	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.356	0.644	0.000
D59.3 Haemolytic-uraemic syndrome	0.356	0.644	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.356	0.644	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.356	0.644	0.000
E53.9 Vitamin B deficiency, unspecified	0.355	0.645	0.000
C91.0 Acute lymphoblastic leukaemia	0.353	0.647	0.000
C91.1 Chronic lymphocytic leukaemia	0.353	0.647	0.000
D86.8 Sarcoidosis of other and combined sites	0.353	0.647	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.352	0.648	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.352	0.648	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.351	0.649	0.000
L10-L14 Bullous disorders	0.351	0.649	0.000
C04 Malignant neoplasm of floor of mouth	0.351	0.649	0.000
C80 Malignant neoplasm without specification of site	0.349	0.651	0.000
D86.1 Sarcoidosis of lymph nodes	0.349	0.651	0.000
D52 Folate deficiency anaemia	0.348	0.652	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.347	0.653	0.000
N13 Obstructive and reflux uropathy	0.344	0.656	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.342	0.658	0.000
C78.0 Secondary malignant neoplasm of lung	0.342	0.658	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.340	0.660	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.339	0.661	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.339	0.661	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.338	0.662	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.338	0.662	0.000
D58.1 Hereditary elliptocytosis	0.338	0.662	0.000
C62.1 Descended testis	0.337	0.662	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.336	0.664	0.000
D83.9 Common variable immunodeficiency, unspecified	0.335	0.665	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.334	0.666	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.331	0.669	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.331	0.669	0.000
L50-L54 Urticaria and erythema	0.330	0.670	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.672	0.328
D60.8 Other acquired pure red cell aplasias	0.327	0.673	0.000
D60.1 Transient acquired pure red cell aplasia	0.327	0.673	0.000
D60.0 Chronic acquired pure red cell aplasia	0.327	0.673	0.000
D67 Hereditary factor IX deficiency	0.324	0.675	0.000
C31 Malignant neoplasm of accessory sinuses	0.324	0.676	0.000
E44.1 Mild protein-energy malnutrition	0.323	0.676	0.000
E44.0 Moderate protein-energy malnutrition	0.323	0.676	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.323	0.677	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.323	0.677	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.323	0.677	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.323	0.677	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.323	0.677	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.322	0.678	0.000
D84 Other immunodeficiencies	0.319	0.681	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.316	0.684	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.315	0.685	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.313	0.687	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.313	0.687	0.000
D69 Purpura and other haemorrhagic conditions	0.312	0.688	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.311	0.688	0.000
D56.1 Beta thalassaemia	0.310	0.690	0.000
D83.8 Other common variable immunodeficiencies	0.309	0.691	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.309	0.691	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.309	0.691	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.309	0.691	0.000
L41.9 Parapsoriasis, unspecified	0.309	0.691	0.000
L41.8 Other parapsoriasis	0.309	0.691	0.000
L41.5 Retiform parapsoriasis	0.309	0.691	0.000
L41.4 Large plaque parapsoriasis	0.309	0.691	0.000
L41.3 Small plaque parapsoriasis	0.309	0.691	0.000
L41.2 Lymphomatoid papulosis	0.309	0.691	0.000
L41.1 Pityriasis lichenoides chronica	0.309	0.691	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.309	0.691	0.000
L44.9 Papulosquamous disorder, unspecified	0.309	0.691	0.000
L44.8 Other specified papulosquamous disorders	0.309	0.691	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.309	0.691	0.000
L44.3 Lichen ruber moniliformis	0.309	0.691	0.000
L44.2 Lichen striatus	0.309	0.691	0.000
L44.1 Lichen nitidus	0.309	0.691	0.000
L44.0 Pityriasis rubra pilaris	0.309	0.691	0.000
C03 Malignant neoplasm of gum	0.309	0.691	0.000
C13 Malignant neoplasm of hypopharynx	0.309	0.691	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.307	0.693	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.306	0.694	0.000
N84.1 Polyp of cervix uteri	0.000	0.694	0.306
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.305	0.695	0.000
N13.6 Pyonephrosis	0.304	0.696	0.000
C76.0 Head, face and neck	0.303	0.697	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.303	0.697	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.303	0.697	0.000
E03.9 Hypothyroidism, unspecified	0.302	0.698	0.000
C10 Malignant neoplasm of oropharynx	0.301	0.699	0.000
C38.4 Pleura	0.296	0.704	0.000
C60 Malignant neoplasm of penis	0.296	0.704	0.000
C04.0 Anterior floor of mouth	0.295	0.705	0.000
D56.9 Thalassaemia, unspecified	0.294	0.705	0.000
D56.8 Other thalassaemias	0.294	0.705	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.294	0.705	0.000
D56.2 Delta-beta thalassaemia	0.294	0.705	0.000
D56.0 Alpha thalassaemia	0.294	0.705	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.294	0.705	0.000
D55.8 Other anaemias due to enzyme disorders	0.294	0.705	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.294	0.705	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.294	0.705	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.294	0.705	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.294	0.705	0.000
D57.8 Other sickle-cell disorders	0.294	0.705	0.000
D57.3 Sickle-cell trait	0.294	0.705	0.000
D57.2 Double heterozygous sickling disorders	0.294	0.705	0.000
D57.1 Sickle-cell anaemia without crisis	0.294	0.705	0.000
D57.0 Sickle-cell anaemia with crisis	0.294	0.705	0.000
Q65 Congenital deformities of hip	0.293	0.707	0.000
C04.9 Floor of mouth, unspecified	0.292	0.708	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.291	0.709	0.000
C33 Malignant neoplasm of trachea	0.291	0.709	0.000
D81.9 Combined immunodeficiency, unspecified	0.291	0.709	0.000
D81.8 Other combined immunodeficiencies	0.291	0.709	0.000
D81.7 Major histocompatibility complex class II deficiency	0.291	0.709	0.000
D81.6 Major histocompatibility complex class I deficiency	0.291	0.709	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.291	0.709	0.000
D81.4 Nezelof's syndrome	0.291	0.709	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.291	0.709	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.291	0.709	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.291	0.709	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.291	0.709	0.000
C83.0 Small cell (diffuse)	0.291	0.709	0.000
C11 Malignant neoplasm of nasopharynx	0.289	0.711	0.000
Q76 Congenital malformations of spine and bony thorax	0.289	0.711	0.000
C02.4 Lingual tonsil	0.288	0.712	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.288	0.712	0.000
C02.1 Border of tongue	0.288	0.712	0.000
E20-E35 Disorders of other endocrine glands	0.288	0.712	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.287	0.713	0.000
D53.8 Other specified nutritional anaemias	0.287	0.713	0.000
D53.2 Scorbutic anaemia	0.287	0.713	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.287	0.713	0.000
D53.0 Protein deficiency anaemia	0.287	0.713	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.284	0.716	0.000
C34.2 Middle lobe, bronchus or lung	0.283	0.716	0.000
C34.8 Overlapping lesion of bronchus and lung	0.283	0.717	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.283	0.717	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations