TreeWAS – Variant ID: rs162298

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
C44.3 Skin of other and unspecified parts of face	0.974	0.026	0.000
C44 Other malignant neoplasms of skin	0.884	0.116	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.117	0.883
C44.5 Skin of trunk	0.850	0.150	0.000
E03.8 Other specified hypothyroidism	0.000	0.168	0.832
E07 Other disorders of thyroid	0.000	0.168	0.832
C44.6 Skin of upper limb, including shoulder	0.802	0.198	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.796	0.204	0.000
C43 Malignant melanoma of skin	0.779	0.221	0.000
C43.5 Malignant melanoma of trunk	0.765	0.235	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.260	0.740
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.263	0.737
E06 Thyroiditis	0.000	0.275	0.725
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.277	0.723
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.716
E10-E14 Diabetes mellitus	0.000	0.284	0.716
C43.9 Malignant melanoma of skin, unspecified	0.703	0.297	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.298	0.702
E14 Unspecified diabetes mellitus	0.000	0.303	0.697
E10.9 Without complications	0.000	0.326	0.674
E50-E64 Other nutritional deficiencies	0.000	0.329	0.671
E14.9 Without complications	0.000	0.332	0.668
C43.6 Malignant melanoma of upper limb, including shoulder	0.635	0.365	0.000
C44.8 Overlapping lesion of skin	0.634	0.366	0.000
E53 Deficiency of other B group vitamins	0.000	0.368	0.632
E10.4 With neurological complications	0.000	0.370	0.630
C44.9 Malignant neoplasm of skin, unspecified	0.618	0.382	0.000
E14.3 With ophthalmic complications	0.000	0.386	0.614
E10.1 With ketoacidosis	0.000	0.392	0.608
E53.8 Deficiency of other specified B group vitamins	0.000	0.401	0.599
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.402	0.598
E07.1 Dyshormogenetic goitre	0.000	0.404	0.596
E07.0 Hypersecretion of calcitonin	0.000	0.404	0.596
C43.4 Malignant melanoma of scalp and neck	0.592	0.408	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.582	0.418	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.420	0.580
E10.2 With renal complications	0.000	0.420	0.580
E05.8 Other thyrotoxicosis	0.000	0.422	0.578
E61 Deficiency of other nutrient elements	0.000	0.422	0.578
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.429	0.571
C44.0 Skin of lip	0.570	0.430	0.000
C43.8 Overlapping malignant melanoma of skin	0.558	0.442	0.000
C43.0 Malignant melanoma of lip	0.558	0.442	0.000
E10.0 With coma	0.000	0.444	0.556
E06.3 Autoimmune thyroiditis	0.000	0.460	0.540
E07.8 Other specified disorders of thyroid	0.000	0.476	0.524
E14.8 With unspecified complications	0.000	0.476	0.523
E06.5 Other chronic thyroiditis	0.000	0.480	0.520
E06.4 Drug-induced thyroiditis	0.000	0.480	0.520
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.480	0.520
E06.1 Subacute thyroiditis	0.000	0.480	0.520
E06.0 Acute thyroiditis	0.000	0.480	0.520
E14.2 Withrenal complications	0.000	0.484	0.516
C43.3 Malignant melanoma of other and unspecified parts of face	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12 Malnutrition-related diabetes mellitus	0.000	0.486	0.513
E61.1 Iron deficiency	0.000	0.490	0.510
E06.9 Thyroiditis, unspecified	0.000	0.493	0.507
E14.5 With peripheral circulatory complications	0.000	0.493	0.507
E10.7 With multiple complications	0.000	0.496	0.504
E14.7 With multiple complications	0.000	0.500	0.500
E14.4 With neurological complications	0.000	0.500	0.500
E14.0 With coma	0.000	0.500	0.500
E10.6 With other specified complications	0.000	0.501	0.499
E14.1 With ketoacidosis	0.000	0.506	0.494
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.519	0.481
E63 Other nutritional deficiencies	0.000	0.519	0.481
E56 Other vitamin deficiencies	0.000	0.519	0.481
E51 Thiamine deficiency	0.000	0.519	0.481
E50 Vitamin A deficiency	0.000	0.519	0.481
E60 Dietary zinc deficiency	0.000	0.519	0.481
E59 Dietary selenium deficiency	0.000	0.519	0.481
E58 Dietary calcium deficiency	0.000	0.519	0.481
E54 Ascorbic acid deficiency	0.000	0.519	0.481
E52 Niacin deficiency [pellagra]	0.000	0.519	0.481
E16 Other disorders of pancreatic internal secretion	0.000	0.522	0.478
E53.9 Vitamin B deficiency, unspecified	0.000	0.524	0.476
C44.2 Skin of ear and external auricular canal	0.472	0.528	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.470	0.530	0.000
E13 Other specified diabetes mellitus	0.000	0.535	0.464
E10.8 With unspecified complications	0.000	0.544	0.456
E53.1 Pyridoxine deficiency	0.000	0.547	0.453
E53.0 Riboflavin deficiency	0.000	0.547	0.453
C44.4 Skin of scalp and neck	0.434	0.566	0.000
C44.7 Skin of lower limb, including hip	0.417	0.583	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.584	0.416
E61.2 Magnesium deficiency	0.000	0.584	0.416
E61.9 Deficiency of nutrient element, unspecified	0.000	0.586	0.414
E61.8 Deficiency of other specified nutrient elements	0.000	0.586	0.414
E61.7 Deficiency of multiple nutrient elements	0.000	0.586	0.414
E61.6 Vanadium deficiency	0.000	0.586	0.414
E61.5 Molybdenum deficiency	0.000	0.586	0.414
E61.4 Chromium deficiency	0.000	0.586	0.414
E61.3 Manganese deficiency	0.000	0.586	0.414
E61.0 Copper deficiency	0.000	0.586	0.414
E14.6 With other specified complications	0.000	0.588	0.412
E40-E46 Malnutrition	0.000	0.597	0.403
E16.2 Hypoglycaemia, unspecified	0.000	0.616	0.384
E12.9 Without complications	0.000	0.632	0.368
E12.8 With unspecified complications	0.000	0.632	0.368
E12.7 With multiple complications	0.000	0.632	0.368
E12.6 With other specified complications	0.000	0.632	0.368
E12.5 With peripheral circulatory complications	0.000	0.632	0.368
E12.4 With neurological complications	0.000	0.632	0.368
E12.3 With ophthalmic complications	0.000	0.632	0.368
E12.2 With renal complications	0.000	0.632	0.368
E12.1 With ketoacidosis	0.000	0.632	0.368
E12.0 With coma	0.000	0.632	0.368
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.636	0.364
E16.1 Other hypoglycaemia	0.000	0.647	0.353
E50.9 Vitamin A deficiency, unspecified	0.000	0.655	0.345
E50.8 Other manifestations of vitamin A deficiency	0.000	0.655	0.345
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.655	0.345
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.655	0.345
E50.5 Vitamin A deficiency with night blindness	0.000	0.655	0.345
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.655	0.345
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.655	0.345
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.655	0.345
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.655	0.345
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.655	0.345
E51.9 Thiamine deficiency, unspecified	0.000	0.655	0.345
E51.8 Other manifestations of thiamine deficiency	0.000	0.655	0.345
E51.2 Wernicke's encephalopathy	0.000	0.655	0.345
E51.1 Beriberi	0.000	0.655	0.345
E56.9 Vitamin deficiency, unspecified	0.000	0.655	0.345
E56.8 Deficiency of other vitamins	0.000	0.655	0.345
E56.1 Deficiency of vitamin K	0.000	0.655	0.345
E56.0 Deficiency of vitamin E	0.000	0.655	0.345
E63.9 Nutritional deficiency, unspecified	0.000	0.655	0.345
E63.8 Other specified nutritional deficiencies	0.000	0.655	0.345
E63.1 Imbalance of constituents of food intake	0.000	0.655	0.345
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.655	0.345
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.655	0.345
E64.8 Sequelae of other nutritional deficiencies	0.000	0.655	0.345
E64.3 Sequelae of rickets	0.000	0.655	0.345
E64.2 Sequelae of vitamin C deficiency	0.000	0.655	0.345
E64.1 Sequelae of vitamin A deficiency	0.000	0.655	0.345
E64.0 Sequelae of protein-energy malnutrition	0.000	0.655	0.345
C44.1 Skin of eyelid, including canthus	0.344	0.656	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.657	0.343
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.657	0.343
E16.4 Abnormal secretion of gastrin	0.000	0.657	0.343
E16.3 Increased secretion of glucagon	0.000	0.657	0.343
E10.3 With ophthalmic complications	0.000	0.657	0.343
E13.8 With unspecified complications	0.000	0.667	0.333
E13.7 With multiple complications	0.000	0.667	0.333
E13.6 With other specified complications	0.000	0.667	0.333
E13.5 With peripheral circulatory complications	0.000	0.667	0.333
E13.4 With neurological complications	0.000	0.667	0.333
E13.2 With renal complications	0.000	0.667	0.333
E13.1 With ketoacidosis	0.000	0.667	0.333
E13.0 With coma	0.000	0.667	0.333
E13.9 Without complications	0.000	0.678	0.322
E10.5 With peripheral circulatory complications	0.000	0.688	0.311
E55 Vitamin D deficiency	0.001	0.694	0.305
E13.3 With ophthalmic complications	0.000	0.702	0.298
E04 Other non-toxic goitre	0.000	0.710	0.290
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.711	0.289
E45 Retarded development following protein-energy malnutrition	0.000	0.711	0.289
E43 Unspecified severe protein-energy malnutrition	0.000	0.711	0.289
E42 Marasmic kwashiorkor	0.000	0.711	0.289
E41 Nutritional marasmus	0.000	0.711	0.289
E40 Kwashiorkor	0.000	0.711	0.289
E65-E68 Obesity and other hyperalimentation	0.000	0.727	0.273
E04.0 Non-toxic diffuse goitre	0.000	0.754	0.246
E55.0 Rickets, active	0.001	0.781	0.219
E04.8 Other specified non-toxic goitre	0.000	0.792	0.208
E44.1 Mild protein-energy malnutrition	0.000	0.793	0.207
E44.0 Moderate protein-energy malnutrition	0.000	0.793	0.207
E67 Other hyperalimentation	0.000	0.804	0.196
E68 Sequelae of hyperalimentation	0.000	0.804	0.196
E46 Unspecified protein-energy malnutrition	0.000	0.827	0.173
E04.1 Non-toxic single thyroid nodule	0.000	0.858	0.142
E67.8 Other specified hyperalimentation	0.000	0.859	0.141
E67.3 Hypervitaminosis D	0.000	0.859	0.141
E67.2 Megavitamin-B6 syndrome	0.000	0.859	0.141
E67.1 Hypercarotenaemia	0.000	0.859	0.141
E67.0 Hypervitaminosis A	0.000	0.859	0.141
E66 Obesity	0.000	0.876	0.124
E65 Localised adiposity	0.001	0.893	0.106
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.894	0.106
E04.9 Non-toxic goitre, unspecified	0.000	0.898	0.102
C43.7 Malignant melanoma of lower limb, including hip	0.093	0.907	0.000
E66.1 Drug-induced obesity	0.000	0.911	0.089
E66.0 Obesity due to excess calories	0.000	0.912	0.088
E20-E35 Disorders of other endocrine glands	0.000	0.924	0.076
E66.8 Other obesity	0.000	0.934	0.066
E04.2 Non-toxic multinodular goitre	0.000	0.936	0.063
E28 Ovarian dysfunction	0.000	0.939	0.061
G12.2 Motor neuron disease	0.000	0.940	0.060
E26 Hyperaldosteronism	0.000	0.940	0.060
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.945	0.054
E32 Diseases of thymus	0.000	0.945	0.054
E31 Polyglandular dysfunction	0.000	0.945	0.054
E30 Disorders of puberty, not elsewhere classified	0.000	0.945	0.054
E25 Adrenogenital disorders	0.000	0.945	0.054
E28.3 Primary ovarian failure	0.000	0.948	0.052
E20 Hypoparathyroidism	0.000	0.949	0.050
E24 Cushing's syndrome	0.000	0.950	0.050
G12 Spinal muscular atrophy and related syndromes	0.000	0.950	0.049
E29 Testicular dysfunction	0.000	0.951	0.049
E26.0 Primary hyperaldosteronism	0.000	0.951	0.049
E23 Hypofunction and other disorders of pituitary gland	0.000	0.955	0.045
E55.9 Vitamin D deficiency, unspecified	0.001	0.956	0.043
E28.9 Ovarian dysfunction, unspecified	0.000	0.956	0.044
E28.8 Other ovarian dysfunction	0.000	0.956	0.044
E28.1 Androgen excess	0.000	0.956	0.044
E28.0 Oestrogen excess	0.000	0.956	0.044
E26.9 Hyperaldosteronism, unspecified	0.000	0.957	0.043
E26.8 Other hyperaldosteronism	0.000	0.957	0.043
E26.1 Secondary hyperaldosteronism	0.000	0.957	0.043
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.958	0.042
E22 Hyperfunction of pituitary gland	0.000	0.958	0.042
G11 Hereditary ataxia	0.000	0.959	0.041
G11.9 Hereditary ataxia, unspecified	0.000	0.959	0.041
E11 Non-insulin-dependent diabetes mellitus	0.039	0.960	0.002
E34 Other endocrine disorders	0.000	0.960	0.040
E25.9 Adrenogenital disorder, unspecified	0.000	0.961	0.039
E25.8 Other adrenogenital disorders	0.000	0.961	0.039
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.961	0.039
E30.9 Disorder of puberty, unspecified	0.000	0.961	0.039
E30.8 Other disorders of puberty	0.000	0.961	0.039
E30.1 Precocious puberty	0.000	0.961	0.039
E30.0 Delayed puberty	0.000	0.961	0.039
E31.9 Polyglandular dysfunction, unspecified	0.000	0.961	0.039
E31.8 Other polyglandular dysfunction	0.000	0.961	0.039
E31.1 Polyglandular hyperfunction	0.000	0.961	0.039
E31.0 Autoimmune polyglandular failure	0.000	0.961	0.039
E32.9 Disease of thymus, unspecified	0.000	0.961	0.039
E32.8 Other diseases of thymus	0.000	0.961	0.039
E32.1 Abscess of thymus	0.000	0.961	0.039
E32.0 Persistent hyperplasia of thymus	0.000	0.961	0.039
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.961	0.039
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.961	0.039
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.961	0.039
E11.5 With peripheral circulatory complications	0.039	0.961	0.000
E23.0 Hypopituitarism	0.000	0.961	0.039
E28.2 Polycystic ovarian syndrome	0.000	0.962	0.038
E11.4 With neurological complications	0.038	0.962	0.000
E11.1 With ketoacidosis	0.036	0.963	0.000
E20.8 Other hypoparathyroidism	0.000	0.963	0.036
E20.1 Pseudohypoparathyroidism	0.000	0.963	0.036
E20.0 Idiopathic hypoparathyroidism	0.000	0.963	0.036
E24.2 Drug-induced Cushing's syndrome	0.000	0.964	0.036
E24.8 Other Cushing's syndrome	0.000	0.964	0.036
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.964	0.036
E24.3 Ectopic ACTH syndrome	0.000	0.964	0.036
E24.1 Nelson's syndrome	0.000	0.964	0.036
G12.9 Spinal muscular atrophy, unspecified	0.000	0.964	0.036
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.964	0.036
G12.1 Other inherited spinal muscular atrophy	0.000	0.964	0.036
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.964	0.036
E29.9 Testicular dysfunction, unspecified	0.000	0.964	0.035
E29.8 Other testicular dysfunction	0.000	0.964	0.035
E29.0 Testicular hyperfunction	0.000	0.964	0.035
E11.6 With other specified complications	0.035	0.965	0.001
E24.9 Cushing's syndrome, unspecified	0.000	0.966	0.034
G11.4 Hereditary spastic paraplegia	0.000	0.967	0.033
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.967	0.032
E23.1 Drug-induced hypopituitarism	0.000	0.967	0.032
E24.0 Pituitary-dependent Cushing's disease	0.000	0.967	0.032
E11.2 With renal complications	0.032	0.968	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.968	0.032
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.968	0.032
E22.0 Acromegaly and pituitary gigantism	0.000	0.968	0.032
E29.1 Testicular hypofunction	0.000	0.970	0.030
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.970	0.030
G14 Postpolio syndrome	0.000	0.970	0.030
G10 Huntington's disease	0.000	0.970	0.030
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.970	0.030
E22.8 Other hyperfunction of pituitary gland	0.000	0.970	0.030
G11.8 Other hereditary ataxias	0.000	0.970	0.030
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.970	0.030
G11.2 Late-onset cerebellar ataxia	0.000	0.970	0.030
G11.1 Early-onset cerebellar ataxia	0.000	0.970	0.030
G11.0 Congenital nonprogressive ataxia	0.000	0.970	0.030
E23.7 Disorder of pituitary gland, unspecified	0.000	0.971	0.029
E11.7 With multiple complications	0.028	0.971	0.001
E34.5 Androgen resistance syndrome	0.000	0.971	0.029
E34.4 Constitutional tall stature	0.000	0.971	0.029
E34.3 Short stature, not elsewhere classified	0.000	0.971	0.029
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.971	0.029
E34.1 Other hypersecretion of intestinal hormones	0.000	0.971	0.029
E11.8 With unspecified complications	0.027	0.972	0.001
E34.8 Other specified endocrine disorders	0.000	0.972	0.027
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.973	0.027
E11.3 With ophthalmic complications	0.026	0.974	0.000
E23.2 Diabetes insipidus	0.000	0.975	0.025
E34.0 Carcinoid syndrome	0.000	0.975	0.025
E23.6 Other disorders of pituitary gland	0.000	0.976	0.024
E21.3 Hyperparathyroidism, unspecified	0.000	0.976	0.024
E34.9 Endocrine disorder, unspecified	0.000	0.976	0.023
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.977	0.023
E21.4 Other specified disorders of parathyroid gland	0.000	0.977	0.023
E21.2 Other hyperparathyroidism	0.000	0.978	0.022
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.000	0.978	0.022
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.000	0.978	0.022
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.000	0.978	0.022
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.000	0.978	0.022
Z95.0 Presence of cardiac pacemaker	0.000	0.979	0.021
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.980	0.020
E22.1 Hyperprolactinaemia	0.000	0.981	0.019
E11.0 With coma	0.017	0.982	0.002
L43.9 Lichen planus, unspecified	0.000	0.983	0.017
E27 Other disorders of adrenal gland	0.000	0.985	0.015
O47.1 False labour at or after 37 completed weeks of gestation	0.014	0.986	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.987	0.013
E70-E90 Metabolic disorders	0.000	0.988	0.012
E21.0 Primary hyperparathyroidism	0.000	0.988	0.012
E27.5 Adrenomedullary hyperfunction	0.000	0.989	0.011
E27.0 Other adrenocortical overactivity	0.000	0.989	0.011
L43 Lichen planus	0.000	0.989	0.011
I89.0 Lymphoedema, not elsewhere classified	0.000	0.990	0.010
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.990	0.010
N95.2 Postmenopausal atrophic vaginitis	0.010	0.990	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.990	0.009
E89.2 Postprocedural hypoparathyroidism	0.000	0.991	0.009
L43.8 Other lichen planus	0.000	0.991	0.009
E88 Other metabolic disorders	0.000	0.991	0.009
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.991	0.009
E27.9 Disorder of adrenal gland, unspecified	0.000	0.991	0.009
E89.0 Postprocedural hypothyroidism	0.000	0.991	0.009
H44.2 Degenerative myopia	0.009	0.991	0.000
E84 Cystic fibrosis	0.000	0.991	0.009
E79 Disorders of purine and pyrimidine metabolism	0.000	0.991	0.009
E77 Disorders of glycoprotein metabolism	0.000	0.991	0.009
E76 Disorders of glycosaminoglycan metabolism	0.000	0.991	0.009
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.991	0.009
E72 Other disorders of amino-acid metabolism	0.000	0.991	0.009
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.991	0.009
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.991	0.009
E27.8 Other specified disorders of adrenal gland	0.000	0.991	0.009
E70 Disorders of aromatic amino-acid metabolism	0.000	0.992	0.008
E83 Disorders of mineral metabolism	0.000	0.992	0.008
E27.1 Primary adrenocortical insufficiency	0.000	0.992	0.008
L43.3 Subacute (active) lichen planus	0.000	0.992	0.008
L43.2 Lichenoid drug reaction	0.000	0.992	0.008
L43.1 Bullous lichen planus	0.000	0.992	0.008
L43.0 Hypertrophic lichen planus	0.000	0.992	0.008
E74 Other disorders of carbohydrate metabolism	0.000	0.992	0.008
E88.8 Other specified metabolic disorders	0.000	0.992	0.008
E27.2 Addisonian crisis	0.000	0.992	0.007
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.992	0.007
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.992	0.007
E89.5 Postprocedural testicular hypofunction	0.000	0.992	0.007
E89.1 Postprocedural hypoinsulinaemia	0.000	0.992	0.007
E88.2 Lipomatosis, not elsewhere classified	0.000	0.993	0.007
E83.3 Disorders of phosphorus metabolism	0.000	0.993	0.007
M79.67 Pain in limb (Ankle and foot)	0.000	0.993	0.007
O47 False labour	0.007	0.993	0.000
E73 Lactose intolerance	0.000	0.993	0.007
E88.9 Metabolic disorder, unspecified	0.000	0.993	0.007
E78.2 Mixed hyperlipidaemia	0.000	0.993	0.007
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.993	0.007
E71.3 Disorders of fatty-acid metabolism	0.000	0.993	0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.993	0.006
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.993	0.006
E71.0 Maple-syrup-urine disease	0.000	0.993	0.006
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.993	0.006
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.993	0.006
E72.5 Disorders of glycine metabolism	0.000	0.993	0.006
E72.4 Disorders of ornithine metabolism	0.000	0.993	0.006
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.993	0.006
E72.2 Disorders of urea cycle metabolism	0.000	0.993	0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.993	0.006
E72.0 Disorders of amino-acid transport	0.000	0.993	0.006
E75.6 Lipid storage disorder, unspecified	0.000	0.993	0.006
E75.5 Other lipid storage disorders	0.000	0.993	0.006
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.993	0.006
E75.3 Sphingolipidosis, unspecified	0.000	0.993	0.006
E75.2 Other sphingolipidosis	0.000	0.993	0.006
E75.1 Other gangliosidosis	0.000	0.993	0.006
E75.0 GM2 gangliosidosis	0.000	0.993	0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.993	0.006
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.993	0.006
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.993	0.006
E76.2 Other mucopolysaccharidoses	0.000	0.993	0.006
E76.1 Mucopolysaccharidosis, type II	0.000	0.993	0.006
E76.0 Mucopolysaccharidosis, type I	0.000	0.993	0.006
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.993	0.006
E77.8 Other disorders of glycoprotein metabolism	0.000	0.993	0.006
E77.1 Defects in glycoprotein degradation	0.000	0.993	0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.993	0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.993	0.006
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.993	0.006
E79.1 Lesch-Nyhan syndrome	0.000	0.993	0.006
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.993	0.006
E84.9 Cystic fibrosis, unspecified	0.000	0.993	0.006
E84.8 Cystic fibrosis with other manifestations	0.000	0.993	0.006
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.993	0.006
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.993	0.006
E83.1 Disorders of iron metabolism	0.000	0.993	0.007
E89.3 Postprocedural hypopituitarism	0.000	0.993	0.006
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.994	0.006
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.994	0.006
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.994	0.006
O47.9 False labour, unspecified	0.006	0.994	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.006	0.994	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.006	0.994	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.994	0.006
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.994	0.006
E70.2 Disorders of tyrosine metabolism	0.000	0.994	0.006
E70.1 Other hyperphenylalaninaemias	0.000	0.994	0.006
E70.0 Classical phenylketonuria	0.000	0.994	0.006
E88.3 Tumour lysis syndrome	0.000	0.994	0.006
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.006	0.994	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.994	0.006
E83.8 Other disorders of mineral metabolism	0.000	0.994	0.006
E83.2 Disorders of zinc metabolism	0.000	0.994	0.006
E83.0 Disorders of copper metabolism	0.000	0.994	0.006
C48.2 Peritoneum, unspecified	0.006	0.994	0.000
C49.0 Connective and soft tissue of head, face and neck	0.006	0.994	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.994	0.006
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.994	0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.994	0.006
E74.2 Disorders of galactose metabolism	0.000	0.994	0.006
E74.1 Disorders of fructose metabolism	0.000	0.994	0.006
E74.0 Glycogen storage disease	0.000	0.994	0.006
E85 Amyloidosis	0.000	0.994	0.006
E70.3 Albinism	0.000	0.994	0.005
E78.8 Other disorders of lipoprotein metabolism	0.000	0.994	0.006
C48.1 Specified parts of peritoneum	0.006	0.994	0.000
E83.5 Disorders of calcium metabolism	0.000	0.994	0.006
C48.0 Retroperitoneum	0.005	0.994	0.000
E73.8 Other lactose intolerance	0.000	0.995	0.005
E73.1 Secondary lactase deficiency	0.000	0.995	0.005
E73.0 Congenital lactase deficiency	0.000	0.995	0.005
C49.5 Connective and soft tissue of pelvis	0.005	0.995	0.000
E89.4 Postprocedural ovarian failure	0.000	0.995	0.005
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.005	0.995	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.995	0.005
C49.1 Connective and soft tissue of upper limb, including shoulder	0.005	0.995	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.995	0.005
C49.9 Connective and soft tissue, unspecified	0.005	0.995	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
E78.3 Hyperchylomicronaemia	0.000	0.995	0.005
O47.0 False labour before 37 completed weeks of gestation	0.005	0.995	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.005	0.995	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.005	0.995	0.000
E78.6 Lipoprotein deficiency	0.000	0.995	0.005
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.995	0.004
Z04.3 Examination and observation following other accident	0.005	0.995	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.005	0.995	0.000
E78.4 Other hyperlipidaemia	0.000	0.995	0.005
S02.60 Fracture of mandible (closed)	0.000	0.995	0.005
S42.30 Fracture of shaft of humerus (closed)	0.000	0.995	0.005
E85.8 Other amyloidosis	0.000	0.996	0.004
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.996	0.004
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.996	0.004
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.996	0.004
C49.4 Connective and soft tissue of abdomen	0.004	0.996	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.996	0.004
Z45 Adjustment and management of implanted device	0.000	0.996	0.004
C49.3 Connective and soft tissue of thorax	0.004	0.996	0.000
E85.4 Organ-limited amyloidosis	0.000	0.996	0.004
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.004	0.996	0.000
C46 Kaposi's sarcoma	0.004	0.996	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.996	0.004
I08.0 Disorders of both mitral and aortic valves	0.004	0.996	0.000
Z39.1 Care and examination of lactating mother	0.000	0.996	0.004
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.996	0.004
Z45.3 Adjustment and management of implanted hearing device	0.000	0.996	0.004
Z45.1 Adjustment and management of infusion pump	0.000	0.996	0.004
E80 Disorders of porphyrin and bilirubin metabolism	0.001	0.996	0.003
C45 Mesothelioma	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.996	0.003
E85.3 Secondary systemic amyloidosis	0.000	0.996	0.003
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.996	0.004
E85.9 Amyloidosis, unspecified	0.000	0.997	0.003
Z45.8 Adjustment and management of other implanted devices	0.000	0.997	0.003
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
R05 Cough	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.003	0.997	0.000
Z39 Postpartum care and examination	0.000	0.997	0.003
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
C46.9 Kaposi's sarcoma, unspecified	0.003	0.997	0.000
C46.8 Kaposi's sarcoma of multiple organs	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations