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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1628578
log Bayes Factor = 85.1639
Chromosome 6   position 29,695,502  (GRCh37) Explore rs1628578 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.999 0.001 0.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E10.1 With ketoacidosis
0.993 0.007 0.000
K51 Ulcerative colitis
0.000 0.008 0.992
K51.9 Ulcerative colitis, unspecified
0.000 0.013 0.987
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.984 0.016 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.018 0.982
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.974 0.026 0.000
# Top node
0.974 0.026 0.000
M25 Other joint disorders, not elsewhere classified
0.972 0.028 0.000
M20-M25 Other joint disorders
0.972 0.028 0.000
L40-L45 Papulosquamous disorders
0.971 0.029 0.000
M07.3 Other psoriatic arthropathies
0.969 0.031 0.000
M07 Psoriatic and enteropathic arthropathies
0.968 0.032 0.000
M05-M14 Inflammatory polyarthropathies
0.967 0.033 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.034 0.966
Chapter XII Diseases of the skin and subcutaneous tissue
0.961 0.039 0.000
E10.3 With ophthalmic complications
0.960 0.040 0.000
M25.5 Pain in joint
0.955 0.045 0.000
D50-D53 Nutritional anaemias
0.953 0.047 0.000
M25.56 Pain in joint (Lower leg)
0.950 0.050 0.000
D50 Iron deficiency anaemia
0.946 0.054 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.944 0.056 0.000
K50-K52 Noninfective enteritis and colitis
0.022 0.056 0.922
E14 Unspecified diabetes mellitus
0.944 0.056 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.944 0.056 0.000
D50.9 Iron deficiency anaemia, unspecified
0.943 0.057 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.943 0.057 0.000
M25.4 Effusion of joint
0.942 0.058 0.000
D80-D89 Certain disorders involving the immune mechanism
0.937 0.063 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.937 0.063 0.000
D60-D64 Aplastic and other anaemias
0.932 0.068 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.921 0.079 0.000
K50 Crohn's disease [regional enteritis]
0.001 0.079 0.920
M07.36 Other psoriatic arthropathies (Lower leg)
0.919 0.081 0.000
K50.9 Crohn's disease, unspecified
0.000 0.082 0.918
M07.30 Other psoriatic arthropathies (Multiple sites)
0.912 0.088 0.000
M25.46 Effusion of joint (Lower leg)
0.912 0.088 0.000
M31 Other necrotising vasculopathies
0.911 0.089 0.000
K51.4 Pseudopolyposis of colon
0.000 0.089 0.911
E10.2 With renal complications
0.905 0.095 0.000
K51.8 Other ulcerative colitis
0.000 0.097 0.903
D64 Other anaemias
0.900 0.100 0.000
D86 Sarcoidosis
0.898 0.102 0.000
E16 Other disorders of pancreatic internal secretion
0.891 0.109 0.000
M35 Other systemic involvement of connective tissue
0.890 0.110 0.000
D64.9 Anaemia, unspecified
0.883 0.117 0.000
E10.4 With neurological complications
0.882 0.118 0.000
M60-M63 Disorders of muscles
0.882 0.118 0.000
M31.6 Other giant cell arteritis
0.878 0.122 0.000
D55-D59 Haemolytic anaemias
0.872 0.128 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.133 0.867
E16.2 Hypoglycaemia, unspecified
0.865 0.135 0.000
M35.0 Sicca syndrome [Sjogren]
0.864 0.136 0.000
K51.5 Mucosal proctocolitis
0.000 0.141 0.859
E50-E64 Other nutritional deficiencies
0.858 0.142 0.000
E13 Other specified diabetes mellitus
0.850 0.150 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.844 0.156 0.000
D68 Other coagulation defects
0.833 0.167 0.000
L40.0 Psoriasis vulgaris
0.831 0.169 0.000
E14.3 With ophthalmic complications
0.831 0.169 0.000
E14.5 With peripheral circulatory complications
0.829 0.170 0.000
M62 Other disorders of muscle
0.827 0.173 0.000
D69 Purpura and other haemorrhagic conditions
0.826 0.174 0.000
D86.0 Sarcoidosis of lung
0.819 0.181 0.000
L50-L54 Urticaria and erythema
0.818 0.182 0.000
E10.0 With coma
0.817 0.183 0.000
M91-M94 Chondropathies
0.815 0.185 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.812 0.188 0.000
E07 Other disorders of thyroid
0.812 0.188 0.000
L10-L14 Bullous disorders
0.807 0.193 0.000
M25.57 Pain in joint (Ankle and foot)
0.807 0.193 0.000
D62 Acute posthaemorrhagic anaemia
0.804 0.196 0.000
M32 Systemic lupus erythematosus
0.798 0.202 0.000
M86-M90 Other osteopathies
0.794 0.206 0.000
D59 Acquired haemolytic anaemia
0.789 0.211 0.000
M25.9 Joint disorder, unspecified
0.788 0.212 0.000
L40.1 Generalised pustular psoriasis
0.780 0.220 0.000
M25.42 Effusion of joint (Upper arm)
0.774 0.226 0.000
M25.54 Pain in joint (Hand)
0.771 0.229 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.766 0.234 0.000
E10.8 With unspecified complications
0.766 0.234 0.000
D86.9 Sarcoidosis, unspecified
0.764 0.236 0.000
M12 Other specific arthropathies
0.763 0.237 0.000
E10.7 With multiple complications
0.763 0.237 0.000
M35.7 Hypermobility syndrome
0.762 0.238 0.000
E14.9 Without complications
0.757 0.243 0.000
Chapter VI Diseases of the nervous system
0.752 0.248 0.000
M10 Gout
0.750 0.250 0.000
M11 Other crystal arthropathies
0.750 0.250 0.000
D83 Common variable immunodeficiency
0.749 0.251 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.749 0.251 0.000
M62.8 Other specified disorders of muscle
0.745 0.255 0.000
D68.9 Coagulation defect, unspecified
0.744 0.256 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.744 0.256 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.743 0.257 0.000
K50.8 Other Crohn's disease
0.000 0.257 0.743
D66 Hereditary factor VIII deficiency
0.738 0.262 0.000
M25.47 Effusion of joint (Ankle and foot)
0.738 0.262 0.000
M25.59 Pain in joint (Site unspecified)
0.737 0.263 0.000
M25.53 Pain in joint (Forearm)
0.736 0.264 0.000
M25.44 Effusion of joint (Hand)
0.735 0.265 0.000
E10.6 With other specified complications
0.734 0.266 0.000
L40.3 Pustulosis palmaris et plantaris
0.732 0.268 0.000
D68.0 Von Willebrand's disease
0.732 0.268 0.000
K50.1 Crohn's disease of large intestine
0.000 0.270 0.730
D69.6 Thrombocytopenia, unspecified
0.729 0.271 0.000
E13.9 Without complications
0.727 0.273 0.000
G35 Multiple sclerosis
0.726 0.274 0.000
D68.8 Other specified coagulation defects
0.726 0.274 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.726 0.274 0.000
M07.6 Other enteropathic arthropathies
0.721 0.279 0.000
E55 Vitamin D deficiency
0.721 0.279 0.000
E07.8 Other specified disorders of thyroid
0.718 0.282 0.000
E14.2 Withrenal complications
0.718 0.282 0.000
M15-M19 Arthrosis
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.283 0.000
M25.43 Effusion of joint (Forearm)
0.715 0.285 0.000
G30-G32 Other degenerative diseases of the nervous system
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
D80 Immunodeficiency with predominantly antibody defects
0.712 0.288 0.000
M17 Gonarthrosis [arthrosis of knee]
0.707 0.293 0.000
M93 Other osteochondropathies
0.705 0.295 0.000
M25.58 Pain in joint (Other)
0.703 0.297 0.000
E06 Thyroiditis
0.702 0.298 0.000
D86.1 Sarcoidosis of lymph nodes
0.702 0.298 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
D50.1 Sideropenic dysphagia
0.701 0.299 0.000
D86.3 Sarcoidosis of skin
0.701 0.299 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.698 0.302 0.000
M25.2 Flail joint
0.697 0.303 0.000
M25.1 Fistula of joint
0.697 0.303 0.000
D59.1 Other autoimmune haemolytic anaemias
0.697 0.303 0.000
M21 Other acquired deformities of limbs
0.696 0.304 0.000
L44 Other papulosquamous disorders
0.696 0.304 0.000
L41 Parapsoriasis
0.696 0.304 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.696 0.304 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.695 0.305 0.000
M07.38 Other psoriatic arthropathies (Other)
0.695 0.305 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.695 0.305 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.695 0.305 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.695 0.305 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.694 0.306 0.000
M07.5 Arthropathy in ulcerative colitis
0.694 0.306 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.694 0.306 0.000
M07.2 Psoriatic spondylitis
0.694 0.306 0.000
M07.1 Arthritis mutilans
0.694 0.306 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.694 0.306 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.306 0.000
M08 Juvenile arthritis
0.694 0.306 0.000
E05.8 Other thyrotoxicosis
0.692 0.308 0.000
L53 Other erythematous conditions
0.692 0.308 0.000
E14.8 With unspecified complications
0.691 0.309 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.690 0.310 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.687 0.313 0.000
D61 Other aplastic anaemias
0.687 0.313 0.000
M17.9 Gonarthrosis, unspecified
0.687 0.313 0.000
M33 Dermatopolymyositis
0.686 0.314 0.000
E61 Deficiency of other nutrient elements
0.683 0.317 0.000
E14.1 With ketoacidosis
0.679 0.321 0.000
D86.8 Sarcoidosis of other and combined sites
0.678 0.322 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.677 0.323 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.677 0.323 0.000
E14.7 With multiple complications
0.677 0.323 0.000
E14.0 With coma
0.677 0.323 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.677 0.323 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.323 0.677
M31.1 Thrombotic microangiopathy
0.676 0.324 0.000
D67 Hereditary factor IX deficiency
0.676 0.324 0.000
M25.49 Effusion of joint (Site unspecified)
0.675 0.325 0.000
M25.48 Effusion of joint (Other)
0.675 0.325 0.000
M10.0 Idiopathic gout
0.675 0.325 0.000
M31.0 Hypersensitivity angiitis
0.674 0.326 0.000
M31.7 Microscopic polyangiitis
0.674 0.326 0.000
L42 Pityriasis rosea
0.673 0.326 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.673 0.327 0.000
M31.9 Necrotising vasculopathy, unspecified
0.673 0.327 0.000
E15 Nondiabetic hypoglycaemic coma
0.671 0.328 0.000
D82 Immunodeficiency associated with other major defects
0.671 0.328 0.000
D81 Combined immunodeficiencies
0.671 0.328 0.000
D84 Other immunodeficiencies
0.671 0.329 0.000
M89 Other disorders of bone
0.670 0.330 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.331 0.668
D58 Other hereditary haemolytic anaemias
0.668 0.331 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.668 0.332 0.000
I83 Varicose veins of lower extremities
0.000 0.332 0.668
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.667 0.333 0.000
G37 Other demyelinating diseases of central nervous system
0.663 0.337 0.000
D69.4 Other primary thrombocytopenia
0.663 0.337 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.662 0.338 0.000
M30 Polyarteritis nodosa and related conditions
0.658 0.342 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.658 0.342 0.000
L13 Other bullous disorders
0.657 0.343 0.000
M14 Arthropathies in other diseases classified elsewhere
0.656 0.344 0.000
L12 Pemphigoid
0.656 0.344 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.655 0.345 0.000
E14.6 With other specified complications
0.654 0.346 0.000
M25.3 Other instability of joint
0.654 0.346 0.000
M31.8 Other specified necrotising vasculopathies
0.653 0.347 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.653 0.347 0.000
M31.2 Lethal midline granuloma
0.653 0.347 0.000
M17.1 Other primary gonarthrosis
0.653 0.347 0.000
L40.8 Other psoriasis
0.652 0.348 0.000
M25.50 Pain in joint (Multiple sites)
0.652 0.348 0.000
E51 Thiamine deficiency
0.649 0.351 0.000
M34 Systemic sclerosis
0.648 0.351 0.000
M25.41 Effusion of joint (Shoulder region)
0.646 0.354 0.000
D64.4 Congenital dyserythropoietic anaemia
0.645 0.355 0.000
D64.3 Other sideroblastic anaemias
0.645 0.355 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.645 0.355 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.645 0.355 0.000
D64.0 Hereditary sideroblastic anaemia
0.645 0.355 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.643 0.356 0.000
E56 Other vitamin deficiencies
0.643 0.357 0.000
N13 Obstructive and reflux uropathy
0.643 0.357 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.642 0.357 0.000
M86 Osteomyelitis
0.642 0.358 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.640 0.360 0.000
Chapter XX External causes of morbidity and mortality
0.640 0.360 0.000
E13.3 With ophthalmic complications
0.640 0.360 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.639 0.361 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.639 0.361 0.000
E16.4 Abnormal secretion of gastrin
0.639 0.361 0.000
E16.3 Increased secretion of glucagon
0.639 0.361 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.638 0.362 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.638 0.362 0.000
M35.5 Multifocal fibrosclerosis
0.638 0.362 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.638 0.362 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.638 0.362 0.000
M21.0 Valgus deformity, not elsewhere classified
0.637 0.363 0.000
L52 Erythema nodosum
0.637 0.363 0.000
Chapter I Certain infectious and parasitic diseases
0.633 0.367 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.633 0.367 0.000
M61 Calcification and ossification of muscle
0.633 0.367 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.633 0.367 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.632 0.367 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.630 0.370 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.629 0.371 0.000
L53.8 Other specified erythematous conditions
0.626 0.374 0.000
D57 Sickle-cell disorders
0.625 0.374 0.000
D55 Anaemia due to enzyme disorders
0.625 0.374 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.625 0.375 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.625 0.375 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.624 0.376 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.624 0.376 0.000
E55.9 Vitamin D deficiency, unspecified
0.623 0.377 0.000
M62.0 Diastasis of muscle
0.621 0.379 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.379 0.621
E16.0 Drug-induced hypoglycaemia without coma
0.620 0.380 0.000
M25.7 Osteophyte
0.620 0.380 0.000
N10-N16 Renal tubulo-interstitial diseases
0.619 0.381 0.000
E40-E46 Malnutrition
0.617 0.383 0.000
Chapter XIV Diseases of the genitourinary system
0.616 0.384 0.000
L50 Urticaria
0.616 0.384 0.000
D69.0 Allergic purpura
0.616 0.384 0.000
D50.8 Other iron deficiency anaemias
0.616 0.384 0.000
D83.9 Common variable immunodeficiency, unspecified
0.615 0.385 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.615 0.385 0.000
E63 Other nutritional deficiencies
0.615 0.385 0.000
E50 Vitamin A deficiency
0.615 0.385 0.000
E60 Dietary zinc deficiency
0.615 0.385 0.000
E59 Dietary selenium deficiency
0.615 0.385 0.000
E58 Dietary calcium deficiency
0.615 0.385 0.000
E54 Ascorbic acid deficiency
0.615 0.385 0.000
E52 Niacin deficiency [pellagra]
0.615 0.385 0.000
G31.8 Other specified degenerative diseases of nervous system
0.613 0.387 0.000
N00-N08 Glomerular diseases
0.612 0.388 0.000
D69.2 Other nonthrombocytopenic purpura
0.610 0.390 0.000
E13.8 With unspecified complications
0.609 0.391 0.000
E13.7 With multiple complications
0.609 0.391 0.000
E13.6 With other specified complications
0.609 0.391 0.000
E13.5 With peripheral circulatory complications
0.609 0.391 0.000
E13.4 With neurological complications
0.609 0.391 0.000
E13.2 With renal complications
0.609 0.391 0.000
E13.1 With ketoacidosis
0.609 0.391 0.000
E13.0 With coma
0.609 0.391 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.609 0.391 0.000
M25.0 Haemarthrosis
0.608 0.391 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.608 0.392 0.000
B02 Zoster [herpes zoster]
0.605 0.395 0.000
D53 Other nutritional anaemias
0.605 0.395 0.000
E16.1 Other hypoglycaemia
0.604 0.396 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.604 0.396 0.000
Q76 Congenital malformations of spine and bony thorax
0.604 0.396 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.603 0.397 0.000
M62.6 Muscle strain
0.603 0.397 0.000
G70-G73 Diseases of myoneural junction and muscle
0.601 0.399 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.600 0.400 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.598 0.402 0.000
M25.76 Osteophyte (Lower leg)
0.594 0.406 0.000
G31.0 Circumscribed brain atrophy
0.594 0.406 0.000
M62.9 Disorder of muscle, unspecified
0.593 0.407 0.000
M62.4 Contracture of muscle
0.593 0.407 0.000
M62.3 Immobility syndrome (paraplegic)
0.593 0.407 0.000
M62.2 Ischaemic infarction of muscle
0.593 0.407 0.000
M11.2 Other chondrocalcinosis
0.593 0.407 0.000
D69.8 Other specified haemorrhagic conditions
0.592 0.408 0.000
D69.1 Qualitative platelet defects
0.592 0.408 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.592 0.408 0.000
M12.2 Villonodular synovitis (pigmented)
0.591 0.409 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.591 0.409 0.000
M17.5 Other secondary gonarthrosis
0.591 0.409 0.000
D68.5 Primary Thrombophilia
0.590 0.410 0.000
M80-M85 Disorders of bone density and structure
0.588 0.412 0.000
E06.9 Thyroiditis, unspecified
0.587 0.412 0.000
M24 Other specific joint derangements
0.587 0.413 0.000
I73.9 Peripheral vascular disease, unspecified
0.587 0.413 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.587 0.413 0.000
L54 Erythema in diseases classified elsewhere
0.586 0.414 0.000
D56 Thalassaemia
0.586 0.414 0.000
M25.52 Pain in joint (Upper arm)
0.585 0.414 0.000
M60 Myositis
0.585 0.414 0.000
W00-W19 Falls
0.585 0.415 0.000
B00 Herpesviral [herpes simplex] infections
0.585 0.415 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.584 0.416 0.000
M93.9 Osteochondropathy, unspecified
0.583 0.417 0.000
E10.5 With peripheral circulatory complications
0.583 0.417 0.000
E07.1 Dyshormogenetic goitre
0.582 0.418 0.000
E07.0 Hypersecretion of calcitonin
0.582 0.418 0.000
N04 Nephrotic syndrome
0.581 0.419 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.581 0.419 0.000
M35.1 Other overlap syndromes
0.581 0.419 0.000
E14.4 With neurological complications
0.581 0.419 0.000
D73 Diseases of spleen
0.581 0.419 0.000
B02.9 Zoster without complication
0.579 0.421 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.579 0.421 0.000
L10 Pemphigus
0.579 0.421 0.000
L14 Bullous disorders in diseases classified elsewhere
0.579 0.421 0.000
W20-W49 Exposure to inanimate mechanical forces
0.579 0.421 0.000
M93.1 Kienbock's disease of adults
0.577 0.423 0.000
E61.1 Iron deficiency
0.577 0.423 0.000
M89.5 Osteolysis
0.577 0.423 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.577 0.423 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.576 0.424 0.000
D52 Folate deficiency anaemia
0.574 0.425 0.000
M89.3 Hypertrophy of bone
0.574 0.426 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.573 0.427 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.572 0.428 0.000
M32.8 Other forms of systemic lupus erythematosus
0.572 0.428 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.572 0.428 0.000
M65-M68 Disorders of synovium and tendon
0.571 0.429 0.000
K50.0 Crohn's disease of small intestine
0.000 0.429 0.570
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.570 0.430 0.000
M62.88 Other specified disorders of muscle (Other)
0.569 0.431 0.000
M90 Osteopathies in diseases classified elsewhere
0.569 0.431 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.567 0.432 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.567 0.433 0.000
D59.8 Other acquired haemolytic anaemias
0.565 0.434 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.565 0.434 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.565 0.434 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.565 0.434 0.000
D59.3 Haemolytic-uraemic syndrome
0.565 0.434 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.565 0.434 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.565 0.434 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.565 0.435 0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.565 0.435 0.000
M25.98 Joint disorder, unspecified (Other)
0.565 0.435 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.565 0.435 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.565 0.435 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.564 0.436 0.000
L53.0 Toxic erythema
0.562 0.437 0.000
D68.6 Other Thrombophilia
0.562 0.438 0.000
D68.4 Acquired coagulation factor deficiency
0.561 0.439 0.000
M94 Other disorders of cartilage
0.561 0.439 0.000
D64.8 Other specified anaemias
0.561 0.439 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.561 0.439 0.000
Q00-Q07 Congenital malformations of the nervous system
0.560 0.440 0.000
X60-X84 Intentional self-harm
0.559 0.441 0.000
A15-A19 Tuberculosis
0.559 0.441 0.000
M88 Paget's disease of bone [osteitis deformans]
0.556 0.444 0.000
L11 Other acantholytic disorders
0.555 0.445 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.554 0.446 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.554 0.446 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.554 0.446 0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.552 0.448 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.551 0.449 0.000
N04.9 Unspecified
0.550 0.450 0.000
M35.2 Behcet's disease
0.550 0.450 0.000
L13.0 Dermatitis herpetiformis
0.549 0.451 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.549 0.451 0.000
D69.9 Haemorrhagic condition, unspecified
0.548 0.452 0.000
M12.5 Traumatic arthropathy
0.547 0.453 0.000
M12.4 Intermittent hydrarthrosis
0.547 0.453 0.000
M12.1 Kaschin-Beck disease
0.547 0.453 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.547 0.453 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.546 0.454 0.000
M10.02 Idiopathic gout (Upper arm)
0.545 0.455 0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)
0.545 0.455 0.000
N25-N29 Other disorders of kidney and ureter
0.545 0.455 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.544 0.456 0.000
M80 Osteoporosis with pathological fracture
0.544 0.456 0.000
M92 Other juvenile osteochondrosis
0.543 0.457 0.000
K90 Intestinal malabsorption
0.542 0.458 0.000
W50-W64 Exposure to animate mechanical forces
0.542 0.458 0.000
M12.3 Palindromic rheumatism
0.541 0.458 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.459 0.541
L51 Erythema multiforme
0.540 0.460 0.000
M11.8 Other specified crystal arthropathies
0.539 0.461 0.000
D72 Other disorders of white blood cells
0.539 0.461 0.000
M21.8 Other specified acquired deformities of limbs
0.539 0.461 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.538 0.462 0.000
M86.6 Other chronic osteomyelitis
0.538 0.462 0.000
M10.4 Other secondary gout
0.538 0.462 0.000
M10.3 Gout due to impairment of renal function
0.538 0.462 0.000
M10.2 Drug-induced gout
0.538 0.462 0.000
M10.1 Lead-induced gout
0.538 0.462 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.538 0.462 0.000
M11.9 Crystal arthropathy, unspecified
0.538 0.462 0.000
M11.1 Familial chondrocalcinosis
0.538 0.462 0.000
M11.0 Hydroxyapatite deposition disease
0.538 0.462 0.000
D83.8 Other common variable immunodeficiencies
0.537 0.463 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.537 0.463 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.537 0.463 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.537 0.463 0.000
L12.1 Cicatricial pemphigoid
0.537 0.463 0.000
M10.00 Idiopathic gout (Multiple sites)
0.537 0.463 0.000
I73 Other peripheral vascular diseases
0.535 0.465 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.534 0.466 0.000
M25.94 Joint disorder, unspecified (Hand)
0.533 0.467 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.533 0.467 0.000
G36 Other acute disseminated demyelination
0.533 0.467 0.000
M25.40 Effusion of joint (Multiple sites)
0.533 0.467 0.000
L50.0 Allergic urticaria
0.532 0.468 0.000
V20-V29 Motorcycle rider injured in transport accident
0.531 0.469 0.000
B02.2 Zoster with other nervous system involvement
0.531 0.469 0.000
Q40 Other congenital malformations of upper alimentary tract
0.531 0.469 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.531 0.469 0.000
D58.0 Hereditary spherocytosis
0.529 0.470 0.000
N11 Chronic tubulo-interstitial nephritis
0.529 0.471 0.000
Q76.0 Spina bifida occulta
0.527 0.473 0.000
E53 Deficiency of other B group vitamins
0.527 0.473 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.527 0.473 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.526 0.474 0.000
D69.5 Secondary thrombocytopenia
0.526 0.474 0.000
P10-P15 Birth trauma
0.525 0.475 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.525 0.475 0.000
W19 Unspecified fall
0.523 0.477 0.000
M10.06 Idiopathic gout (Lower leg)
0.523 0.477 0.000
D68.1 Hereditary factor XI deficiency
0.523 0.477 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.522 0.478 0.000
Q65 Congenital deformities of hip
0.522 0.478 0.000
N05 Unspecified nephritic syndrome
0.521 0.479 0.000
D61.1 Drug-induced aplastic anaemia
0.521 0.479 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.520 0.480 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.519 0.481 0.000
M00 Pyogenic arthritis
0.518 0.482 0.000
M07.68 Other enteropathic arthropathies (Other)
0.517 0.483 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.517 0.483 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.517 0.483 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.517 0.483 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.517 0.483 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.517 0.483 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.517 0.483 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.517 0.483 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.517 0.483 0.000
E55.0 Rickets, active
0.517 0.483 0.000
E03 Other hypothyroidism
0.517 0.483 0.000
M25.36 Other instability of joint (Lower leg)
0.517 0.483 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.516 0.484 0.000
Q74 Other congenital malformations of limb(s)
0.514 0.485 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
W17 Other fall from one level to another
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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